CN102526304A - Chinese herbal medicament for treating dermatomycosis of rabbits and treatment method thereof - Google Patents
Chinese herbal medicament for treating dermatomycosis of rabbits and treatment method thereof Download PDFInfo
- Publication number
- CN102526304A CN102526304A CN201210016879XA CN201210016879A CN102526304A CN 102526304 A CN102526304 A CN 102526304A CN 201210016879X A CN201210016879X A CN 201210016879XA CN 201210016879 A CN201210016879 A CN 201210016879A CN 102526304 A CN102526304 A CN 102526304A
- Authority
- CN
- China
- Prior art keywords
- vaseline
- parts
- rabbit
- rabbits
- medicament
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a Chinese herbal medicament for treating dermatomycosis of rabbits and a treatment method thereof. The medicament is prepared from 5-15 parts of phellodendron bark as a bulk drug and 5-15 parts of vaseline as an auxiliary drug by pulverizing and mixing uniformly. According to the treatment method, the raw materials are mixed uniformly and then applied to an affected part once per day continuously for 5-7 days, so that dermatomycosis can be healed. The medicament disclosed by the invention selects phellodendron bark as the bulk drug combined with vaseline, and has a good therapeutic effect on dermatomycosis of rabbits clinically; the phellodendron bark has bacteriostatic and antifungal effects, and the vaseline as a chemical raw material has viscosity and an effect of adhering to skin, so that the phellodendron bark and the vaseline after being mixed can continuously play drug effects on the affected part, thereby achieving the healing effect. In treating sick rabbits, the effective rate of treatment is above 90%, and the medicament has the characteristics of being lower in cost, convenient to prepare, simple to use, obvious in effect and the like.
Description
Technical field
The present invention relates to poultry medicament manufacturing technology field, relate in particular to a kind of mycotic Chinese herb medicine of treatment rabbit skin and Therapeutic Method thereof.
Background technology
Rabbit skin mycosis is claimed the tinea of losing hair or feathers again, is one type of infecting both domestic animals and human contact dermatosis that infectiousness is extremely strong, is to be caused by fungal infection such as Trichophyton mentagrophytes and little spore mycetes.This disease is bigger for the harm of meat rabbit, each at age rabbit all can take place, wherein the sickness rate of young rabbit is higher than young rabbit and adult rabbit.Symptoms such as folliculitis and gargalesthesia appear that scurf increases, forms a scab, loses hair or feathers, oozes out, in main infringement Corii seu pilus Leporis; Can cause that rabbit malnutrition, growth retardation, the price of deed reduce even death, directly influence the rabbit quality, reduce fertility performance of kind of rabbit and the survival rate of young rabbit, cause serious economic loss to rabbit keeping production.Rabbit skin mycosis is worldwide distribution, distributes or popular generation.In some morbidity warrens, the young rabbit speed of growth descends 20%～30%, sickness rate 30%～100%, and mortality rate can reach 20%～40%, and wean back incubation rate descends 25%～50%.
Domestic many scholars investigate rabbit skin mycosis popularity, and the prevalence of report Heilongjiang Province Yichun rabbit warren kind rabbit skin infection tinea bacterium such as Pang Shuhua reaches more than 50%; Dermatosis is broken out in Dinghai District rex rabbit fields, Zhoushan city, report Zhejiang Province such as Dong Shiyi, causes the survival rate of young rabbit to be lower than 70%, and the hide defect ware that produces accounts for more than 60%.People set about studying medicine for this reason, use chemical medicine (comprise azole, propylene amine, chain rate ketoamine class, amorolfine class etc.) and the Chinese herbal medicine Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) inuncts of clotrimazole as primary raw material.Yet in the process of long-term treatment and repeat administration, fungus is also as the easy drug resistance that causes for medicine of antibacterial.Therefore, developing the mycotic Chinese medicine preparation of a kind of treatment rabbit skin has great importance.
Summary of the invention
The present invention is directed to and be used to treat the existing defective of rabbit skin mycosis medicine in the market, provide a kind of effective preparation convenient, the cheap mycotic Chinese medicine inuncts of treatment rabbit skin.
Technical scheme of the present invention is achieved in that
The mycotic Chinese herb medicine of a kind of treatment rabbit skin is characterized in that: it is to be pulverized the back mix homogeneously according to following weight proportion and formed by crude drug Cortex Phellodendri, adjuvant medicine vaseline: 5～15 parts of Cortex Phellodendris, 5～15 parts in vaseline.
As preferably, the consumption of crude drug Cortex Phellodendri, adjuvant medicine vaseline is: 10 parts of Cortex Phellodendris, 10 parts in vaseline.
The mycotic Therapeutic Method of a kind of rabbit skin is characterized in that: get after 5～15 parts of Cortex Phellodendris, 5～15 parts of pulverizing of vaseline and mix homogeneously, then affected part is embrocated, embrocated continuously 5～7 days, once a day, just can fully recover.
Adopted the principle of the present invention and the beneficial effect of technique scheme to be:
1. medicine of the present invention select Cortex Phellodendri be crude drug in addition vaseline make up, clinician rabbit skin mycosis is had good therapeutic effect; Cortex Phellodendri itself has antibacterial, antifungic action; Vaseline has viscosity as a kind of industrial chemicals, has Dermallly affixed effect, can continue after two kinds of mixing to bring into play drug effect at affected part, thereby reach the effect of healing.
Through the treatment to ill rabbit, the treatment effective percentage is more than 90%; And this medicine has characteristics such as cost is lower, easy to make, and use is simple, and effect is remarkable.Medicine of the present invention is used for producing, and rabbit is had no side effect, and does not have problems such as drug residue.
2. the former medicine of medicine of the present invention is sufficient, and preparation is simple, and cheap, the medical expense of every rabbit is merely 0.1 yuan, and uses antibiolics treatment cost to be approximately 0.3 yuan.
Description of drawings
Fig. 1 is for carrying out the sketch map of first kind of graininess bacterium colony that sections observation arrives to the rabbit pars affecta skin;
Fig. 2 is for carrying out the sketch map of second kind of graininess bacterium colony that sections observation arrives to the rabbit pars affecta skin;
Fig. 3 is the electrophoresis pattern of fungal DNA after extracting;
Fig. 4 is a fungus G ACA amplified production electrophoretogram;
Fig. 5 is fungus ITS district amplified production electrophoretogram;
Fig. 6 is the sketch map of rabbit ear when ill;
Fig. 7 is the design sketch of rabbit ear after process Drug therapy of the present invention;
Fig. 8 is the sketch map of lagophthalmos eyeball when ill;
Fig. 9 is the design sketch of lagophthalmos eyeball after process Drug therapy of the present invention.
The specific embodiment
The specific embodiment of the present invention is following:
Embodiment:
1, material and method
1.1 material
1.1.1 Cortex Phellodendri is available from the big ways for education of Hangzhou Zhejiang College Of Traditional Chinese Medicine second out-patient department.
1.1.2 experimental rabbit
Picking suffer from dermatomycosis 3 the monthly age New Zealand meat rabbit, provide by Zhejiang Academy of Agricultural Science experiment warren, feeding does not contain the mixed feed of any medicated premix., Zhejiang Academy of Agricultural Science animal and veterinary institute laboratory (to call this laboratory in the following text) Animal House is used for experiment after adapting to 3 days.
1.2 method
1.2.1 Chinese medicine prepares, and Cortex Phellodendri 10g clays into power, vaseline 10g, mix homogeneously gets final product.
1.2.2 every rabbit of experimental rabbit all suffers from dermatomycosis, totally 10, is divided into 2 groups at random, 5 every group.
1.2.3 pathogen separation is identified
Through observed result behind 28 ℃ of cultivations of TSA plate 48h.
1.2.4PCR identify
Extract fungal DNA according to list of references, utilization random primer (GACA) 4; The Molecular Identification of pathomycete has been accomplished in universal primer ITS amplification order-checking.
1.2.5 therapeutic test
Every rabbit of experimental rabbit all suffers from dermatomycosis, totally 10, is divided into 2 groups at random, 5 every group.First group is matched group, does not use any medicine to treat.Second group is the treatment by Chinese herbs group, and affected part is embrocated, and embrocates continuously 5 days, once a day.Before test and embrocate after 5 days and carry out Taking Pictures recording.Carry out that tissue slice is observed HE dyeing and silver dyes embrocating the pars affecta skin of getting two groups of rabbits on the 6th day in the back, compare.
2 results
2.1.1 grow powder on the visible flat board to the graininess bacterium colony, the edge is whole, Fig. 1 shows has milky, and what Fig. 2 showed be yellow-white, bacterium back side yellow.
The visible first kind of bacterium colony of cotton blue dyeing back microscopic examination examined under a microscope and is ring shape weevil form, with a large amount of conidium.Second kind of bacterium is to divide dendritic form at microscopically, with a large amount of conidium.
2.1.2 can get like Fig. 3～5, be accredited as Trichophyton mentagrophytes through PCR.
2.1.3 therapeutic test result
5 rabbit affected parts of Chinese drug-treated group are existing after embrocating 3 days significantly to take a turn for the better, and cures basically after 5 days.The result specifically sees accompanying drawing 6～9 before and after the treatment.
The tissue slice result, through to treatment group and matched group skin histology sections observation, the result finds that treatment organizes rarely seen a spot of inflammatory cell infiltration, the visible significantly granuloma of matched group, part is visible downright bad.
2.1.4 clinical test results
Use this medicine in Hebei adhesion agricultural development company limited and source, Hangzhou Hang Seng attitude culture the company limited rabbit warren and carry out the clinical treatment test, use 240 of meat rabbits altogether, after embrocating 4 days continuously, 216 rabbits are cured fully, the treatment effective percentage reaches 90%.
List of references
1.2.4 JIESHEN is examined document: the author: Zheng Long; Time: 2004; Title: the foundation of laboratory animal dermatosis fungal pathogens nucleic acid detection method, Hebei Medical University's master thesis.
Claims (3)
1. treat the mycotic Chinese herb medicine of rabbit skin for one kind, it is characterized in that: it is to be pulverized the back mix homogeneously according to following weight proportion and formed by crude drug Cortex Phellodendri, adjuvant medicine vaseline: 5～15 parts of Cortex Phellodendris, 5～15 parts in vaseline.
2. treat the mycotic Chinese herb medicine of rabbit skin for one kind, it is characterized in that: the consumption of crude drug Cortex Phellodendri, adjuvant medicine vaseline is: 10 parts of Cortex Phellodendris, 10 parts in vaseline.
3. the mycotic Therapeutic Method of rabbit skin is characterized in that: get after 5～15 parts of Cortex Phellodendris, 5～15 parts of pulverizing of vaseline and mix homogeneously, then affected part is embrocated, embrocated continuously 5～7 days, once a day, just can fully recover.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210016879XA CN102526304A (en) | 2012-01-19 | 2012-01-19 | Chinese herbal medicament for treating dermatomycosis of rabbits and treatment method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210016879XA CN102526304A (en) | 2012-01-19 | 2012-01-19 | Chinese herbal medicament for treating dermatomycosis of rabbits and treatment method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102526304A true CN102526304A (en) | 2012-07-04 |
Family
ID=46335124
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210016879XA Pending CN102526304A (en) | 2012-01-19 | 2012-01-19 | Chinese herbal medicament for treating dermatomycosis of rabbits and treatment method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102526304A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104431406A (en) * | 2014-09-30 | 2015-03-25 | 全椒县大地种植专业合作社 | Feed additive capable of preventing rabbit foot dermatitis |
| CN105284964A (en) * | 2015-11-20 | 2016-02-03 | 湖南惠龙兔业发展有限公司 | Formula for controlling rabbit fungi and application method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003099110A2 (en) * | 2002-05-28 | 2003-12-04 | The Regents Of The University Of California | Herbs and herbal combinations useful for the treatment of microbial infections |
| CN1709466A (en) * | 2005-07-21 | 2005-12-21 | 周国庆 | Combined Chinese-Western medicine mixture for treating mycotic skin disease, and its use method |
| KR20100043438A (en) * | 2008-10-20 | 2010-04-29 | 김중배 | A natural external skin remedy and its production method |
| KR20100072865A (en) * | 2008-12-22 | 2010-07-01 | 한국원자력연구원 | A composition for the prevention, improvement or treatment of acne vulgaris comprising the mixture of extract of phellodendron amurense rupr, houttuynia cordata, paeonia lactiflora pall, agrimonia pilosa ledeb, and glycyrrhiza uralensis fisch as an effective ingredient |
| WO2011105839A2 (en) * | 2010-02-24 | 2011-09-01 | Yang Gean Yung | External skin composition and a production method therefor |
-
2012
- 2012-01-19 CN CN201210016879XA patent/CN102526304A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003099110A2 (en) * | 2002-05-28 | 2003-12-04 | The Regents Of The University Of California | Herbs and herbal combinations useful for the treatment of microbial infections |
| CN1709466A (en) * | 2005-07-21 | 2005-12-21 | 周国庆 | Combined Chinese-Western medicine mixture for treating mycotic skin disease, and its use method |
| KR20100043438A (en) * | 2008-10-20 | 2010-04-29 | 김중배 | A natural external skin remedy and its production method |
| KR20100072865A (en) * | 2008-12-22 | 2010-07-01 | 한국원자력연구원 | A composition for the prevention, improvement or treatment of acne vulgaris comprising the mixture of extract of phellodendron amurense rupr, houttuynia cordata, paeonia lactiflora pall, agrimonia pilosa ledeb, and glycyrrhiza uralensis fisch as an effective ingredient |
| WO2011105839A2 (en) * | 2010-02-24 | 2011-09-01 | Yang Gean Yung | External skin composition and a production method therefor |
Non-Patent Citations (1)
| Title |
|---|
| 周汛等: "23种中药对皮肤浅部真菌感染的体外抗真菌活性研究", 《重庆医科大学学报》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104431406A (en) * | 2014-09-30 | 2015-03-25 | 全椒县大地种植专业合作社 | Feed additive capable of preventing rabbit foot dermatitis |
| CN105284964A (en) * | 2015-11-20 | 2016-02-03 | 湖南惠龙兔业发展有限公司 | Formula for controlling rabbit fungi and application method thereof |
| CN105284964B (en) * | 2015-11-20 | 2018-01-02 | 湖南惠龙兔业发展有限公司 | A kind of rabbit fungus control formula and its application method |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103349180B (en) | Traditional Chinese medicine additive for ram and using method thereof | |
| CN104000014B (en) | A kind of alternative antibiotic feed addictive and preparation method thereof and application | |
| CN103168965B (en) | Anti-stress synbiotics traditional Chinese medicine composition applicable to chicken and preparation method of anti-stress synbiotics traditional Chinese medicine composition | |
| CN101357223A (en) | Preparation method of anti-stress agent for fishing | |
| CN103320365B (en) | Fish-sourced aeromonas hydrophila disease antagonistic strain and application thereof | |
| CN102838389A (en) | Fertilizer-and-drug double-effect bio-organic fertilizer for preventing and treating crop soil-borne diseases and manufacturing method of bio-organic fertilizer | |
| CN104208240A (en) | Traditional Chinese herbal microecological preparation for preventing and treating piglet bacterial dysentery and preparation method thereof | |
| CN103815205B (en) | Feed additive manufactured from orange peel and rice bran for beta-xanthophyll-rich and VE-rich eggs | |
| CN102552411A (en) | Chinese herbal medicine immunopotentiator for sturgeon fingerling | |
| CN102726605A (en) | Micro-ecological synbiotic Chinese herbal medicine feed addictive, preparation method and application thereof | |
| CN104171350B (en) | A kind of duckling cultivation feed additive special | |
| CN104431488A (en) | Preparation process of grass carp feed additive containing eucommia bark powder | |
| CN102273567A (en) | Method for preparing pig feed additive | |
| CN102077928A (en) | Tilapia immune potentiator and preparation method thereof | |
| CN103319617A (en) | Method for extracting purple potato polysaccharide by utilizing ultrasonic wave synergistic with enzymatic method and application | |
| CN102526304A (en) | Chinese herbal medicament for treating dermatomycosis of rabbits and treatment method thereof | |
| CN104642800A (en) | Chinese herbal medicine fermenting preparation for promoting piglet growth | |
| CN101933981A (en) | Traditional Chinese medicinal composition for treating syndrome of liver and gall of aquatic animals and preparation method thereof | |
| CN103497901B (en) | Novel fermentation bed to raise pig composite probiotics preparations | |
| CN103773690A (en) | Open-type culture method of microalgae | |
| CN101874812A (en) | Composite bacteria preparation and application thereof in weight increment of immature livestock and control of diarrhea | |
| CN104171349A (en) | Feed additive for improving reproductive performance of boar | |
| CN105795116A (en) | Immune enhancer used by macrobrachium rosenbergii and application thereof | |
| CN106107215A (en) | Feed additive of Aquatic product and preparation method thereof | |
| CN104257784A (en) | Chinese herbal medicine formula for preventing and treating European foul brood of Apis cerana |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20120704 |