CN102526222A - Traditional Chinese medicine complex prescription for preventing or treating cold and influenza as well as preparation method and application thereof - Google Patents
Traditional Chinese medicine complex prescription for preventing or treating cold and influenza as well as preparation method and application thereof Download PDFInfo
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Abstract
The invention belongs to the technical field of a traditional Chinese medicine complex prescription preparation for preventing or treating cold and influenza. The traditional Chinese medicine complex prescription provided by the invention comprises traditional Chinese medicine ingredients according to the weight mixture ratio: 1 to 40 parts of notopterygium root, 1 to 50 parts of folium isatidis, 1 to 50 parts of dandelion and 1 to 30 parts of dayflower. The traditional Chinese medicine complex prescription preparation adopts the four kinds of traditional Chinese medicine and the proper weight mixture ratio, the exopathogens dispelling, the cold-pungent diaphoresis, the heat clearing and the toxicity removal are fully integrated, the recipe is creative, the antipyretic effect is good, and the traditional Chinese medicine complex prescription preparation is clinically used for preventing or treating upper respiratory tract infection patients with symptoms of cold aversion with fever, headache without sweat, heavy and painful limbs, nasal obstruction and running nose, scratchy or sore throat, epigastric distension and depression, red tongue and sticky greasy coating and the like during the cold syndrome occurrence caused by upper respiratory tract infection diseases such as cold, influenza and the like.
Description
Technical field
The invention belongs to field of medicaments.Be specifically related to a kind ofly be used to prevent and/or treat upper respiratory diseases such as flu, influenza and the compound Chinese medicinal preparation of the syndrome that occurs catching a cold.
Background technology
" flu " traditional Chinese medical science is commonly called as cold.The traditional Chinese medical science thinks that flu is a kind of exogenous diseases that is caused by the ailment said due to cold or exposure invasion and attack, and its morbidity accounts for the first place in exterior syndrome, be modal a kind of.Clinical is primary symptom with headache, nasal obstruction, watery nasal discharge, sneeze, aversion to cold, heating, floating pulse etc.
Ancient Chinese medicine doctor is quite dark to primary disease understanding, and " interior warp " at first proposes flu mainly is due to the affection due to external wind and heat, and " element is asked the bone empty talk " said: " pathogenic wind being the primary pathogen in causing exogenous diseases ... wind from outside go into, make us cold with shivering, heavy sensation of the body, aversion to cold are had a headache in sweating." " element ask beautiful machine really hide opinion " meaning again: " and wind being the first pathogen in causing exogenous disases hereat, modern the person being invaded by wind-cold makes people's vellus hair erecting, and skin closes and is heat, in being, khan and sending out also." treatise on Febrile Diseases has recognized that flu has weight not, and point out the different method of treatment of weight two cards.Say like " Treatise on Febrile Diseases TAI YANG syndrome ": " TAI YANG syndrome, the headache, the heating, sweating, aversion to wind, the guizhi decoction master it." " TAI YANG syndrome, headache, heating, body is painful, lumbago, arthralgia, aversion to wind, the no perspiration but asthma person, the Ephedrae Decoction master it." from " General Treatise on the Cause and Symptoms of Diseases ", the heresy of the row argument of causing a disease when advocating again, " General Treatise on the Cause and Symptoms of Diseases " meaning: " time row patient; Should warm up when being the spring and anti-cold, should heat during the summer and anti-cold, should be cool during the autumn and anti-heat; Should tremble with fear during the winter and anti-temperature, at that time non-and its gas is arranged, be with among one-year-old; Sick do not have long few, the similar person of rate, then seasonal pathogen is also for this." to " all wind of Renzhai Zhi Zhi Fang, Effective Recipes from Renzhai House " at first proposition flu of piece of writing name of disease in the Northern Song Dynasty, the offspring cures house and continues to use this name now, and will catch a cold and claim with cold is mutual.Unit's " danxi's experiential therapy cold " spells out the disease position and belongs to lung, according to dialectical routine, has established the promptly hot temperature of principle of treatment of primary disease, hot cool two big method of treatment, thereafter empty body flu has been replenished again to set upright to reach evil treatment principle.Traditional Chinese medical science great master professor Yan Dexin thinks that the pathogenesis of respiratory system acute infectious diseases such as influenza is attacked inhibited pulmonary QI for " cold epidemic disease " is outer; Wei Yang is by strongly fragrant, and clear sun is not opened up, strongly fragrant and heat-transformation; The cause of disease is for cold, and the disease folder is warm, and it is main that this type of disease treatment reaches heresy with suffering temperature lung qi dispersing; Using corrigent has been founded the novelty academic thought that acute calenture is controlled from " trembling with fear " opinion with clearing up internal heat by using drugs of bitter in taste and cold in nature.
On forefathers' basis, flu is summed up as four pattern of syndrome, the one, wind-cold syndrome; The 2nd, wind-heat syndrome; The 3rd, syndrome of summer-heat-dampness; The 4th, syndrome of superficies cold and interior heat often adopts relieving the exterior syndrome by diaphoresis, heat-clearing and toxic substances removing, and on behalf of prescription, method such as clearing away summer-heat damp eliminating and controlling Antiphlogistic Powder of Schizonepetae and Ledebouriellae is arranged, Lonicerae and Forsythiae Powder, Xiangru Xin etc.But variation along with weather; The change of living environment; The trend of global warming, and the change of people's dietetic life custom, these are single to induce sweat or the medicine of heat clearing away is difficult to therapeutical effect is preferably played in protean virogenetic acute upper respiratory tract infection.
Summary of the invention
The object of the present invention is to provide a kind of compound Chinese medicinal preparation and application in above-mentioned sign thereof that prevents and/or treats flu (cold), influenza upper respiratory diseases such as (influenzas) appearance flu syndrome; Experimentation shows that this medicine has significantly analgesic, antibiotic, antivirus action.
Though prescription involved in the present invention all has part to embody many pieces of professors Yan Dexin in about the fever caused by exogenous pathogenic factors bibliographical information, and concrete prescription all is not provided, and does not promptly disclose the concrete compatibility of each raw material of Chinese medicine, can't obtain practical application.The present inventor is through research and a large amount of weight proportions of having found said compound Chinese medicinal preparation raw material of Chinese medicine of testing repeatedly; Make the Chinese medicine compound theory of the symptoms such as treatment flu that available data is mentioned become a kind of enforceable technical scheme; Be applied to the field of Chinese medicines, and demonstrate good preventing and therapeutic effect.
For reaching above-mentioned purpose, the technical scheme that the present invention takes is following:
A kind of Chinese medicine compound, the weight proportion of its raw material of Chinese medicine is: Rhizoma Et Radix Notopterygii 1-40 part, Folium Isatidis 1-50 part, Herba Taraxaci 1-50 part, Herba Commelinae 1-30 part.
Above-mentioned Chinese medicine compound, preferred scheme is: Rhizoma Et Radix Notopterygii 4-35 part, Folium Isatidis 5-40 part, Herba Taraxaci 5-40 part, Herba Commelinae 2-20 part.Most preferably: 10 parts of Rhizoma Et Radix Notopterygiis, 15 parts of Folium Isatidiss, 15 parts of Herba Taraxacis, 10 parts of Herba Commelinaes.
Above weight portion can manufacture preparation with gram, kilogram, ton or other unit of weights, as: Rhizoma Et Radix Notopterygii 100g, Folium Isatidis 150g, Herba Taraxaci 150g, Herba Commelinae 100g.Can be made into the pharmaceutical preparation of 500-2000 agent, can be made into 1000 capsules like capsule, tablet can be made into 1000 tablets of tablets, wherein contains in each capsules or each sheet: Rhizoma Et Radix Notopterygii 0.1g, Folium Isatidis 0.15g, Herba Taraxaci 0.15g, Herba Commelinae 0.1g.
Rhizoma Et Radix Notopterygii, latin name: Notopterygium incisum Ting ex H.T.Chang or Notopterygium franchetii H.de Boiss.Another name: river Qiang, silkworm Qiang, RHIZOMA SEU RADIX NOTOPTERYGII, RHIZOMA SEU RADIX NOTOPTERYGII.Medicinal part: rhizome and root.
Folium Isatidis, latin name: Isatis indigotica Fort. another name: Folium Isatidis, roadside Folium Isatidis, Isatis indigotica Fort. leaf, Folium acanthaceous indigo, careless Folium Isatidis, polygonum tinctorium ait. leaf etc.Medicinal part: leaf.
Herba Taraxaci, latin name: Taraxacum mongolicum Hand.Mazz, alkali ground Herba Taraxaci Taraxacumborealisinense Kitam. another name: Pu Gongcao, edible Herba Taraxaci, wet the bed grass, Western Herba Taraxaci etc.Medicinal part: flower, leaf, stem, root.
Herba Commelinae, latin name: Commelina communis L. another name: chicken SHECAO, nose are hacked grass, green bamboo etc.Medicinal part: herb.
One of method for preparing of above-mentioned Chinese medicine compound comprises the following steps:
(1) prepares each crude drug by weight ratio;
(2), be condensed into extractum after the filtration decoction liquor with active constituents of medicine with ready crude drug decocte with water.
Above-mentioned step (2), preferably scheme is decocte with water 1-3 time, each 6-10 times of water gaging decocted 0.5-2 hour, merged decoction liquor, crossed and filtered filtrating, was condensed into the extractum that proportion is 1.0-1.3 after the filtration decoction liquor.
Chinese medicine compound of the present invention also can adopt in the existing pharmaceutical field other conventional method preparation, can add various pharmaceutically acceptable carriers when needing, and can be made into any pharmaceutically acceptable dosage form.Described carrier comprises the conventional diluent of pharmaceutical field, excipient, binding agent, disintegrating agent, wetting agent, lubricant, surfactant etc., as: starch, sucrose, dextrin, lactose, magnesium stearate, cellulose family and derivant thereof, gelatin, polyvinylpyrrolidone etc.Traditional Chinese compound medicine of the present invention is preferably processed oral formulations, as: granule, tablet, capsule, ointment, oral liquid, soft extract, pill etc.; Also can be made into injection, as: liquid drugs injection, freeze-dried powder, aseptic powder injection, transfusion etc.
Compound Chinese medicinal preparation of the present invention, its active ingredient be by Rhizoma Et Radix Notopterygii, Folium Isatidis, and Herba Taraxaci, Herba Commelinae 4 flavor Chinese medicines are processed; Take suitable weight proportion, full side integrates that hot temperature is dispersed, relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, heat-clearing and toxic substances removing, and prescription has much intention; It is effective to bring down a fever, and clinically is used for upper respiratory diseases such as preventing/treating flu, influenza and the syndrome that occurs catching a cold, and disease is seen fever with aversion to cold; Lossless headache, heavy limbs pain, nasal obstruction watery nasal discharge; Throat is itched bitterly, oppression sensation over the epigastrium and anorexia, upper respiratory tract infection persons such as red tongue greasy fur.
The specific embodiment
In order to understand the present invention better, below Chinese medicine preparation feasibility of the present invention is described, is proved pharmacology result of the present invention through Test Example through embodiment.
Embodiment 1: the preparation of the active component of medicine of the present invention
(1) takes by weighing raw material of Chinese medicine (is example with 10 times of material proportional quantities) by following weight proportion: 100 parts of Rhizoma Et Radix Notopterygiis, 150 parts of Folium Isatidiss, 150 parts of Herba Taraxacis, 100 parts of Herba Commelinaes.
(2) take by weighing the Rhizoma Et Radix Notopterygii of above-mentioned weight proportion, Folium Isatidis, Herba Taraxaci; Herba Commelinae, the decocte with water secondary, 10 times of water gagings decocted 2 hours for the first time; For the second time 8 times of water gagings decocted 1 hour, and decocting liquid filters, merging filtrate and to be concentrated into relative density be 1.25 (about 60 ℃); Get extractum, be the active component of this invention medicine.
Embodiment 2: the preparation of the active component of medicine of the present invention
(1) takes by weighing raw material of Chinese medicine (is example with 10 times of material proportional quantities) by following weight proportion: 200 parts of Rhizoma Et Radix Notopterygiis, 300 parts of Folium Isatidiss, 300 parts of Herba Taraxacis, 200 parts of Herba Commelinaes.
(2) take by weighing the Rhizoma Et Radix Notopterygii of above-mentioned weight proportion, Folium Isatidis, Herba Taraxaci, Herba Commelinae, preparation process makes extractum with embodiment 1, must be somebody's turn to do the active component of invention medicine.
Embodiment 3: the preparation of the active component of medicine of the present invention
(1) takes by weighing raw material of Chinese medicine (is example with 10 times of material proportional quantities) by following weight proportion: 400 parts of Rhizoma Et Radix Notopterygiis, 600 parts of Folium Isatidiss, 600 parts of Herba Taraxacis, 400 parts of Herba Commelinaes.
(2) take by weighing the Rhizoma Et Radix Notopterygii of above-mentioned weight proportion, Folium Isatidis, Herba Taraxaci, Herba Commelinae, preparation process makes extractum with embodiment 1, must be somebody's turn to do the active component of invention medicine.
The preparation of the active component of embodiment 4 medicines of the present invention
(1) takes by weighing raw material of Chinese medicine (is example with 10 times of material proportional quantities) by following weight proportion: 350 parts of Rhizoma Et Radix Notopterygiis, 500 parts of Folium Isatidiss, 500 parts of Herba Taraxacis, 350 parts of Herba Commelinaes.
(2) take by weighing the Rhizoma Et Radix Notopterygii of above-mentioned weight proportion, Folium Isatidis, Herba Taraxaci, Herba Commelinae, preparation process makes extractum with embodiment 1, must be somebody's turn to do the active component of invention medicine.
Embodiment 5: the preparation of tablet
(1) get 60 parts of the active components that prepare by method among the embodiment 1, add 40 parts in dextrin, mix thoroughly, vacuum drying (40-60 ℃) is ground into fine powder (crossing 100 mesh sieves) after do.
(2) get the said medicine fine powder, mix with 60 parts of dextrin and 30 parts of starch again, add 5 part of 10% starch slurry and process soft material, granulate, place 70 ℃ of dry backs in 12 mesh sieve granulate with 14 mesh sieves, add 0.8 part of magnesium stearate mixing after, tabletting promptly gets tablet.
Embodiment 6: the preparation of granule
Get 60 parts of the active components that prepare by method among the embodiment 1, with 120 parts of sucrose, 80 parts in dextrin, mixing.Add 75% ethanol mixing again, process soft material, granulate with 14 mesh sieves, place 75 ℃ of dry backs in 12 mesh sieve granulate, behind the mixing, packing promptly gets granule.
Embodiment 7: the preparation of oral liquid
Get the active component 60ml for preparing by method among the embodiment 1, add an amount of sodium benzoate solution, add the 500ml purified water, filter.Add purified water to 1000ml, promptly get oral liquid.
Embodiment 8: the preparation of capsule
(1) get 60 parts of the active components that prepare by method among the embodiment 1, add 40 parts in dextrin, mix thoroughly, vacuum drying (40-60 ℃) is ground into fine powder (crossing 100 mesh sieves) after do.
(2) get the said medicine fine powder, mix with 60 parts of dextrin and 30 parts of starch, add 5 part of 10% starch slurry and process soft material, granulate with 14 mesh sieves, place 80 ℃ of dry backs in 12 mesh sieve granulate, behind the mixing, the snap fit capsule of packing into promptly gets capsule.
The experimentation of Test Example 1 antiviral, bacteriostasis
Receive the reagent thing to make active component by experimental example 1.
Dosage design in vivo test according to people's clinical application amount, is converted out mice in vivo test dosage according to animals and human beings kilogram dose,equivalent, is decided to be middle dosage, is equivalent to clinical equivalent dosage.Other establishes high dose is 2 times of middle dosage, and low dosage is 1/2 times of middle dosage; In vitro tests is mixed with 1g crude drug/ml with tri-distilled water, and water proof boils sterilization in 20 minutes.
The positive control drug ribavirin granule, Pharmaceutical Co Ltd, China Univ. of Pharmacy produces, and lot number is 091210; Clinical consumption 0.45g granule/sky; Be calculated as 0.075g crude drug/kg by 60 kg body weight, 2 times of clinical equivalent dosage are selected in vivo test for use, and mice is with 0.165g granule/kg.Benzylpenicillin sodium for injection, lot number: 110369024, produce by promise pharmaceutcal corporation, Ltd in the stone medicine group, as positive control drug, be used for bacteriostatic test.
Animal CD-(ICR)/SPF mice, 13-15g, male and female half and half.Raise in barrier environment.
Virus influenza virus A-prime Mus lung adapted strain FM1.
Antibacterial type strain: staphylococcus aureus 26112 (ATCC25923), escherichia coli 4413 (ATCC25922), Pseudomonas aeruginosa 10211 (ATCC27853), each 1 strain of Klebsiella pneumonia.Clinical separation strain: staphylococcus aureus 361, escherichia coli 178, bacillus pyocyaneus 109, Klebsiella pneumonia 160.
The bacteria culture media nutrient agar, nutrient broth medium.
One, interior resisting virus effect (to the influence of mice influenza property pneumonia)
1, test method
Get the 13-15g mice,, be respectively the normal control group, virus control group, high, medium and low three dose groups of test sample of the present invention, 10 every group by the body weight random packet.Except that the normal control group, mice is slightly anaesthetized with ether, infects every 0.05ml with 15LD50 influenza virus liquid (FM1) collunarium.Begin administration after the infection, every day 1 time, continuous 5 days.After taking by weighing the mice body weight on the 6th day, fixing, blood-letting, dissection are won full lung and are weighed, and calculate the lung ponderal index one by one, and obtain lung index suppression ratio.
Lung ponderal index=[heavy (the g)/body weight (g) of lung] * 100
Lung ponderal index value is big, and expression pneumonopathy range degree is serious.Each group lung exponential quantity is carried out t check, comparable group differences property.
2, result of the test
Test shows; Irritate stomach with high, medium and low three dose groups of test sample of the present invention and give mice; Institute's amount of reagent all has inhibitory action in various degree to the pneumonia that the influenza virus infecting mouse causes, high, middle dose groups mice weight increase, lung ponderal index value reduce obviously.Result of the test is seen table 1.
Two, extracorporeal bacteria inhibitor test (agar dilution)
1, test method
Reagent is added in the Nutrient agar that has melted with 1/8 ratio, and do serial doubling dilution, pour into the plating medium that becomes to contain different liquor strengths.In addition use turbidimetry, each strain that will increase bacterium 16h than turbid to the Maxwell No. 1 pipe (300,000,000 bacterium/ml), again each bacterium is cooked suitable dilution, each is drawn 5 μ l and drips on flat board, establishes the antibacterial contrast simultaneously, positive drug contrasts.The plate of having inoculated is placed 37 ℃ of incubators, and observed result behind the 24h writes down each bacteria growing and minimum inhibitory concentration MIC.
2, result of the test
Test sample of the present invention all has inhibitory action in various degree to 4 kind of 8 strain antibacterial of try.Result of the test is seen table 2.
The influence of the susceptible toxicity pneumonia of each sample convection current of table 1 mice (X ± SD)
Compare * P＜0.05 with the virus control group, * * P＜0.01
Each medicine appearance of table 2 is to the inhibitory action of antibacterial
Annotate: "-" asepsis growth, "+" has bacteria growing.The penicillin contrast all suppresses the examination bacterium.
Claims (9)
1. Chinese medicine compound, the weight proportion of its raw material of Chinese medicine is: Rhizoma Et Radix Notopterygii 1-40 part, Folium Isatidis 1-50 part, Herba Taraxaci 1-50 part, Herba Commelinae 1-30 part.
2. Chinese medicine compound as claimed in claim 1 is characterized in that: the weight proportion of raw material of Chinese medicine is: Rhizoma Et Radix Notopterygii 4-35 part, Folium Isatidis 5-40 part, Herba Taraxaci 5-40 part, Herba Commelinae 2-20 part.
3. Chinese medicine compound as claimed in claim 2 is characterized in that: the weight proportion of raw material of Chinese medicine is: 10 parts of Rhizoma Et Radix Notopterygiis, 15 parts of Folium Isatidiss, 15 parts of Herba Taraxacis, 10 parts of Herba Commelinaes.
4. the method for preparing of the described arbitrary Chinese medicine compound of claim 1-3, it comprises the following steps:
(1) prepares each crude drug by weight ratio;
(2), be condensed into extractum after the filtration decoction liquor with active constituents of medicine with ready crude drug decocte with water.
5. the method for preparing of Chinese medicine compound as claimed in claim 4; It is characterized in that: step (2) decocte with water 1-3 time, each 6-10 times of water gaging decocted 0.5-2 hour, merged decoction liquor; Cross and filter filtrating, be condensed into the extractum that proportion is 1.0-1.3 after the filtration decoction liquor.
6. compound Chinese medicinal preparation, its effective ingredient is the described arbitrary Chinese medicine compound of claim 1-3, its dosage form is any pharmaceutically said dosage form.
7. compound Chinese medicinal preparation as claimed in claim 6 is characterized in that: its dosage form is granule, tablet, capsule, powder, pill, syrup, oral liquid or injection.
8. the described arbitrary Chinese medicine compound of claim 1-3 shows the application in the flu syndrome medicine preventing and/or treating upper respiratory tract infection such as flu, influenza.
9. claim 6 or 7 described compound Chinese medicinal preparation are preventing and/or treating upper respiratory diseases such as flu, influenza and application in the syndrome medicine that occurs catching a cold.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1088591C (en) * | 1999-07-12 | 2002-08-07 | 蔡祺源 | Medicine for curing and preventing upper respiratory infection and its preparing method |
| CN100355451C (en) * | 2006-01-17 | 2007-12-19 | 何天乐 | Cold-treating influenza-preventing medicine |
| KR20100028190A (en) * | 2008-09-04 | 2010-03-12 | 김종심 | Dandelion processing method and dandelion juice |
| CN101874843A (en) * | 2009-12-10 | 2010-11-03 | 陈爱中 | Medicament for treating influenza |
| CN102018750A (en) * | 2009-09-09 | 2011-04-20 | 景玲 | Traditional Chinese medicine for treating cold and parotitis |
-
2012
- 2012-02-03 CN CN2012100247594A patent/CN102526222A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1088591C (en) * | 1999-07-12 | 2002-08-07 | 蔡祺源 | Medicine for curing and preventing upper respiratory infection and its preparing method |
| CN100355451C (en) * | 2006-01-17 | 2007-12-19 | 何天乐 | Cold-treating influenza-preventing medicine |
| KR20100028190A (en) * | 2008-09-04 | 2010-03-12 | 김종심 | Dandelion processing method and dandelion juice |
| CN102018750A (en) * | 2009-09-09 | 2011-04-20 | 景玲 | Traditional Chinese medicine for treating cold and parotitis |
| CN101874843A (en) * | 2009-12-10 | 2010-11-03 | 陈爱中 | Medicament for treating influenza |
Non-Patent Citations (1)
| Title |
|---|
| 胡晓贞等: "青英颗粒治疗急性上呼吸道感染临床观察", 《上海中医药大学学报》 * |
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Application publication date: 20120704 |