CN102483416A - 诊断前列腺癌的工具和方法 - Google Patents

诊断前列腺癌的工具和方法 Download PDF

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Publication number
CN102483416A
CN102483416A CN2010800345524A CN201080034552A CN102483416A CN 102483416 A CN102483416 A CN 102483416A CN 2010800345524 A CN2010800345524 A CN 2010800345524A CN 201080034552 A CN201080034552 A CN 201080034552A CN 102483416 A CN102483416 A CN 102483416A
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CN
China
Prior art keywords
acid
sphingol
metid
phosphatid ylcholine
prostate cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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CN2010800345524A
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English (en)
Chinese (zh)
Inventor
B·卡姆朗格
B·贝唐
R·雷兹卡
E·莱博尔德
K·容
M·莱恩
G·克里斯蒂安森
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Charite Universitaetsmedizin Berlin
Metanomics Health GmbH
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Charite Universitaetsmedizin Berlin
Metanomics Health GmbH
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Application filed by Charite Universitaetsmedizin Berlin, Metanomics Health GmbH filed Critical Charite Universitaetsmedizin Berlin
Publication of CN102483416A publication Critical patent/CN102483416A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57555—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the prostate

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
CN2010800345524A 2009-06-04 2010-06-02 诊断前列腺癌的工具和方法 Pending CN102483416A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09161956.9 2009-06-04
EP09161956 2009-06-04
PCT/EP2010/057680 WO2010139711A1 (en) 2009-06-04 2010-06-02 Means and methods for diagnosing prostate carcinomas

Publications (1)

Publication Number Publication Date
CN102483416A true CN102483416A (zh) 2012-05-30

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CN2010800345524A Pending CN102483416A (zh) 2009-06-04 2010-06-02 诊断前列腺癌的工具和方法

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US (1) US20120122243A1 (https=)
EP (3) EP2804001B1 (https=)
JP (2) JP5933432B2 (https=)
CN (1) CN102483416A (https=)
CA (1) CA2764049A1 (https=)
DE (1) DE112010002253T5 (https=)
ES (1) ES2516866T3 (https=)
PL (1) PL2438445T3 (https=)
WO (1) WO2010139711A1 (https=)

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CN104034658A (zh) * 2013-03-05 2014-09-10 精工爱普生株式会社 分析装置及方法、光学元件及其设计方法以及电子设备
CN104076021A (zh) * 2013-03-28 2014-10-01 精工爱普生株式会社 光学器件、检测装置及电子设备
CN104422683A (zh) * 2013-09-10 2015-03-18 精工爱普生株式会社 分析装置、分析方法、光学元件及电子设备
CN104614462A (zh) * 2015-02-11 2015-05-13 中国人民解放军第四军医大学 一种高原肺水肿诊断标志物及其应用和诊断试剂盒
CN105572109A (zh) * 2014-10-31 2016-05-11 山田节郎 肿瘤检查用组合物及肿瘤检查用试纸
CN106415274A (zh) * 2014-03-26 2017-02-15 梅坦诺米克斯保健有限公司 基于代谢物组的血液样本质量的测定方法和手段
CN107589196A (zh) * 2017-11-02 2018-01-16 南京拓睿谱基因科技有限公司 一种预示肺癌脑转移的小分子标志物及在诊断方面的应用
CN109564207A (zh) * 2016-06-02 2019-04-02 梅塔博隆股份有限公司 用于检测和定量代谢物的质谱方法
CN110749732A (zh) * 2019-11-27 2020-02-04 中南大学 诊断多发性骨髓瘤的血液代谢物标志物及应用
CN111721751A (zh) * 2020-06-30 2020-09-29 四川大学华西医院 一种检测结直肠恶性肿瘤的装置
CN111999404A (zh) * 2020-08-14 2020-11-27 中元伯瑞生物科技(珠海横琴)有限公司 神经酸在制备甲状腺恶性肿瘤的检测试剂中的应用
CN112748195A (zh) * 2020-12-23 2021-05-04 沈阳农业大学 一种利用gc-nci-ms对脂肪酸、氨基酸和多官能团有机酸同时检测的方法
CN114527222A (zh) * 2022-02-22 2022-05-24 广州市番禺区中心医院 前列腺癌相关标志物及其应用
CN118604356A (zh) * 2024-06-06 2024-09-06 温州医科大学 用于前列腺癌风险分层的无创诊断生物标志物组合及其应用
CN119269471A (zh) * 2024-09-19 2025-01-07 青岛大学 基于拉曼光谱的肿瘤细胞转移能力检测方法
WO2025054293A1 (en) * 2023-09-05 2025-03-13 National Taiwan University Biomarker for prostate cancer

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KR101821551B1 (ko) 2008-06-20 2018-01-25 아지노모토 가부시키가이샤 전립선 질환의 평가 방법
US9285378B2 (en) 2010-01-29 2016-03-15 Metanomics Gmbh Means and methods for diagnosing heart failure in a subject
TWI596494B (zh) 2012-03-05 2017-08-21 Ｏｐｋｏ診斷法有限責任公司 預測前列腺癌風險及前列腺腺體體積之方法及裝置
ES2688121T3 (es) 2012-10-02 2018-10-31 Metanomics Health Gmbh Medios y procedimientos de diagnóstico de la reaparición de cáncer de próstata después de prostatectomía
ES2534732B1 (es) * 2013-08-05 2016-04-21 Servicio Andaluz De Salud Método de clasificación, diagnóstico y seguimiento de individuos con riesgo de padecer cáncer de pulmón mediante el análisis de sudor
JP6222629B2 (ja) * 2013-08-29 2017-11-01 花王株式会社 排尿障害のバイオマーカー
KR101838133B1 (ko) 2013-10-04 2018-03-14 주식회사 씨스퀘어 사르코신 대사산물 중 포름알데히드를 이용한 전립선암 진단 시험지, 그 제조 방법 및 이를 이용한 전립선암 진단에 필요한 정보를 제공하는 방법
GB201322034D0 (en) 2013-12-12 2014-01-29 Almac Diagnostics Ltd Prostate cancer classification
US10274496B2 (en) 2014-01-17 2019-04-30 University Of Washington Biomarkers for detecting and monitoring colon cancer
US12326453B2 (en) 2014-03-28 2025-06-10 Opko Diagnostics, Llc Compositions and methods for active surveillance of prostate cancer
KR102505543B1 (ko) * 2014-03-28 2023-03-02 옵코 다이어그노스틱스, 엘엘씨 전립선암 진단에 관한 조성물 및 방법
PT3253800T (pt) 2015-03-27 2021-04-28 Opko Diagnostics Llc Padrões de antigénio da próstata e suas utilizações
EP3229026A1 (en) * 2016-04-06 2017-10-11 Universite De Bordeaux Biomarkers for the diagnosis of inflammation-related diseases
CN116148481A (zh) * 2017-03-31 2023-05-23 学校法人庆应义塾 并用抗癌剂的感受性判定标记
CN108362804B (zh) * 2018-02-27 2019-01-29 山东英盛生物技术有限公司 一种检测血液样品中dha含量的方法及试剂盒
EP4045905A4 (en) * 2019-10-17 2023-10-11 Biomark Cancer Systems Inc. METHOD OF DIAGNOSING EARLY STAGE NON-SMALL CELL LUNG CANCER
WO2021213494A1 (en) * 2020-04-23 2021-10-28 YatHing Biotechnology Company Limited Methods related to the diagnosis of prostate cancer
JP2023533959A (ja) * 2020-07-08 2023-08-07 ボード オブ レジェンツ，ザ ユニバーシティ オブ テキサス システム 前立腺がんの検出及び治療方法
CN112630363A (zh) * 2020-12-31 2021-04-09 四川大学华西医院 一种MXene生物响应特性代谢组学分析方法
US20250369973A1 (en) * 2022-09-02 2025-12-04 Baker Heart and Diabetes Institute Prognostic markers
CN118091155B (zh) * 2024-02-29 2025-02-18 汕头大学医学院第二附属医院 大肠癌代谢标志物及其在诊断大肠癌中的应用

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US4540884A (en) 1982-12-29 1985-09-10 Finnigan Corporation Method of mass analyzing a sample by use of a quadrupole ion trap
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JP2005526962A (ja) 2002-02-28 2005-09-08 メタノミクス ゲーエムベーハー ウント ツェーオー．カーゲーアーアー 物質の混合物を分析する質量分析方法
EP1862797A4 (en) * 2005-03-16 2009-09-16 Ajinomoto Kk DEVICE, METHOD, SYSTEM AND PROGRAM FOR EVALUATING BIOLOGICAL STATES, DEVICE, METHOD AND PROGRAM FOR GENERATING AN EVALUATION FUNCTION AND RECORDING MEDIUM
US20070231822A1 (en) * 2006-02-28 2007-10-04 Michael Mitas Methods for the detection and treatment of cancer
EP2339346B1 (en) * 2006-03-24 2014-09-03 Metanomics GmbH Methods for predicting diabetes type II
CN101454331A (zh) * 2006-03-24 2009-06-10 菲诺梅诺米发现公司 有效用于诊断前列腺癌的生物标记，及其方法
US20090075284A1 (en) * 2006-09-19 2009-03-19 The Regents Of The University Of Michigan Metabolomic profiling of prostate cancer
EP2657705A3 (en) * 2006-09-19 2013-12-25 Metabolon Inc. Biomarkers for prostate cancer and methods using the same
EP2597464B1 (en) * 2007-08-16 2015-02-25 The Regents of the University of Michigan Metabolomic profiling of prostate cancer
US7989630B2 (en) * 2008-04-30 2011-08-02 National Institutes Of Health Represented By The Secretary Of The Department Of Health And Human Services, National Institutes Of Health Radiotracers for imaging P-glycoprotein function
US20120004854A1 (en) * 2008-05-28 2012-01-05 Georgia Tech Research Corporation Metabolic biomarkers for ovarian cancer and methods of use thereof

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104034658A (zh) * 2013-03-05 2014-09-10 精工爱普生株式会社 分析装置及方法、光学元件及其设计方法以及电子设备
CN104076021A (zh) * 2013-03-28 2014-10-01 精工爱普生株式会社 光学器件、检测装置及电子设备
CN104422683A (zh) * 2013-09-10 2015-03-18 精工爱普生株式会社 分析装置、分析方法、光学元件及电子设备
CN106415274A (zh) * 2014-03-26 2017-02-15 梅坦诺米克斯保健有限公司 基于代谢物组的血液样本质量的测定方法和手段
CN105572109A (zh) * 2014-10-31 2016-05-11 山田节郎 肿瘤检查用组合物及肿瘤检查用试纸
CN104614462A (zh) * 2015-02-11 2015-05-13 中国人民解放军第四军医大学 一种高原肺水肿诊断标志物及其应用和诊断试剂盒
CN109564207B (zh) * 2016-06-02 2021-07-02 梅塔博隆股份有限公司 用于检测和定量代谢物的质谱方法
CN109564207A (zh) * 2016-06-02 2019-04-02 梅塔博隆股份有限公司 用于检测和定量代谢物的质谱方法
CN107589196B (zh) * 2017-11-02 2019-09-20 浙江高美生物科技有限公司 一种预示肺癌脑转移的小分子标志物及在诊断方面的应用
CN107589196A (zh) * 2017-11-02 2018-01-16 南京拓睿谱基因科技有限公司 一种预示肺癌脑转移的小分子标志物及在诊断方面的应用
CN110749732A (zh) * 2019-11-27 2020-02-04 中南大学 诊断多发性骨髓瘤的血液代谢物标志物及应用
CN111721751A (zh) * 2020-06-30 2020-09-29 四川大学华西医院 一种检测结直肠恶性肿瘤的装置
CN111999404A (zh) * 2020-08-14 2020-11-27 中元伯瑞生物科技(珠海横琴)有限公司 神经酸在制备甲状腺恶性肿瘤的检测试剂中的应用
CN112748195A (zh) * 2020-12-23 2021-05-04 沈阳农业大学 一种利用gc-nci-ms对脂肪酸、氨基酸和多官能团有机酸同时检测的方法
CN114527222A (zh) * 2022-02-22 2022-05-24 广州市番禺区中心医院 前列腺癌相关标志物及其应用
WO2025054293A1 (en) * 2023-09-05 2025-03-13 National Taiwan University Biomarker for prostate cancer
CN118604356A (zh) * 2024-06-06 2024-09-06 温州医科大学 用于前列腺癌风险分层的无创诊断生物标志物组合及其应用
CN119269471A (zh) * 2024-09-19 2025-01-07 青岛大学 基于拉曼光谱的肿瘤细胞转移能力检测方法
CN119269471B (zh) * 2024-09-19 2026-03-20 青岛大学 基于拉曼光谱的肿瘤细胞转移能力检测方法

Also Published As

Publication number Publication date
JP2012529021A (ja) 2012-11-15
EP2804001A3 (en) 2015-01-14
ES2516866T3 (es) 2014-10-31
EP2438445B1 (en) 2014-07-16
EP2804001B1 (en) 2017-08-09
JP2016153808A (ja) 2016-08-25
EP2438445A1 (en) 2012-04-11
PL2438445T3 (pl) 2014-12-31
US20120122243A1 (en) 2012-05-17
JP5933432B2 (ja) 2016-06-08
WO2010139711A1 (en) 2010-12-09
DE112010002253T5 (de) 2013-01-03
CA2764049A1 (en) 2010-12-09
JP6427137B2 (ja) 2018-11-21
EP3296743A1 (en) 2018-03-21
EP2804001A2 (en) 2014-11-19

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Application publication date: 20120530