CN102480969A - 伤口愈合和瘢痕调制方法 - Google Patents

伤口愈合和瘢痕调制方法 Download PDF

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Publication number
CN102480969A
CN102480969A CN2010800392366A CN201080039236A CN102480969A CN 102480969 A CN102480969 A CN 102480969A CN 2010800392366 A CN2010800392366 A CN 2010800392366A CN 201080039236 A CN201080039236 A CN 201080039236A CN 102480969 A CN102480969 A CN 102480969A
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CN
China
Prior art keywords
wound
scar
pharmaceutical composition
corticosteroid
silicone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2010800392366A
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English (en)
Chinese (zh)
Inventor
B·C·凯勒
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Crescendo Therapeutics LLC
Original Assignee
Crescendo Therapeutics LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crescendo Therapeutics LLC filed Critical Crescendo Therapeutics LLC
Publication of CN102480969A publication Critical patent/CN102480969A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN2010800392366A 2009-07-09 2010-07-09 伤口愈合和瘢痕调制方法 Pending CN102480969A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22440809P 2009-07-09 2009-07-09
US61/224,408 2009-07-09
US22621609P 2009-07-16 2009-07-16
US61/226,216 2009-07-16
PCT/US2010/041576 WO2011006100A1 (en) 2009-07-09 2010-07-09 Method of wound healing and scar modulation

Publications (1)

Publication Number Publication Date
CN102480969A true CN102480969A (zh) 2012-05-30

Family

ID=43427950

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010800392366A Pending CN102480969A (zh) 2009-07-09 2010-07-09 伤口愈合和瘢痕调制方法

Country Status (10)

Country Link
US (1) US20110009374A1 (cg-RX-API-DMAC7.html)
EP (1) EP2451280A4 (cg-RX-API-DMAC7.html)
JP (1) JP2012532889A (cg-RX-API-DMAC7.html)
CN (1) CN102480969A (cg-RX-API-DMAC7.html)
AR (1) AR077410A1 (cg-RX-API-DMAC7.html)
AU (1) AU2010271205A1 (cg-RX-API-DMAC7.html)
BR (1) BR112012001098A2 (cg-RX-API-DMAC7.html)
CA (1) CA2767661A1 (cg-RX-API-DMAC7.html)
MX (1) MX2012000434A (cg-RX-API-DMAC7.html)
WO (1) WO2011006100A1 (cg-RX-API-DMAC7.html)

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Publication number Priority date Publication date Assignee Title
CN106573055A (zh) * 2014-06-09 2017-04-19 克洛克斯科技公司 基于硅酮的生物光子组合物及其用途
CN110368498A (zh) * 2019-08-26 2019-10-25 瑞希(重庆)生物科技有限公司 一种促进伤口愈合的制剂及其制备方法
CN113453670A (zh) * 2018-09-28 2021-09-28 乔·斯图丁 类固醇和大分子的透孔递送

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US10258505B2 (en) 2010-09-17 2019-04-16 Alcon Research, Ltd. Balanced phacoemulsification tip
ITMI20111050A1 (it) * 2011-06-10 2012-12-11 Sevecom Spa Uso di emulsionanti in associazione con oleine vegetali in un alimento per animali.
CN103648483A (zh) 2011-06-24 2014-03-19 莫茨制药有限及两合公司 包含洋葱提取物和脂质体的组合物
US9364510B2 (en) 2011-07-19 2016-06-14 Marvphyt Development Llc Botanical composition and methods of manufacture and use
LT2736887T (lt) 2011-07-29 2018-02-12 Karyopharm Therapeutics, Inc. Hidrazidą turintys branduolių transporto moduliatoriai ir jų panaudojimas
WO2013040265A1 (en) * 2011-09-13 2013-03-21 Brigham Young University Technology Commercialization Office Compositions for treating bone diseases and broken bones
US9474685B2 (en) 2011-09-28 2016-10-25 Sure-Shot Medical Device Inc. Apparatus for localized dermatological treatment
GB201120724D0 (en) * 2011-12-01 2012-01-11 Gauthier Rene System and method for alleviating the appearance of scars and/or scar tissue
FR2985064B1 (fr) * 2011-12-23 2016-02-26 Oreal Procede pour delivrer un conseil cosmetique
JP6093007B2 (ja) * 2012-04-27 2017-03-08 ダウ コーニング コーポレーションＤｏｗ Ｃｏｒｎｉｎｇ Ｃｏｒｐｏｒａｔｉｏｎ 基質に有効成分を送達するためのシリコーン系賦形剤を含有する局所用製剤組成物
HUE040427T2 (hu) 2012-05-09 2019-03-28 Biogen Ma Inc Nukleáris transzportmodulátorok és felhasználásuk
US11458199B2 (en) * 2012-08-21 2022-10-04 Opko Pharmaceuticals, Llc Liposome formulations
US9808654B2 (en) * 2013-02-11 2017-11-07 Jan Marini Skin Research Post procedure skin care gel and methods of use thereof
EP2968278B8 (en) * 2013-03-15 2019-05-22 Karyopharm Therapeutics Inc. Methods of promoting wound healing using crm1 inhibitors
CN105122261B (zh) * 2013-04-23 2020-04-24 惠普发展公司，有限责任合伙企业 从遭到破坏的系统启动代码中恢复的方法以及计算装置
EP3492455B1 (en) 2013-06-21 2023-05-17 Karyopharm Therapeutics Inc. 1,2,4-triazoles as nuclear transport modulators and use in the treatment of specific forms of cancer
US11432990B2 (en) 2013-08-30 2022-09-06 ISOS Solutions, LLC Textured apparatus with therapeutic material incorporated therein and methods of manufacturing same
US9226890B1 (en) 2013-12-10 2016-01-05 Englewood Lab, Llc Polysilicone base for scar treatment
EP3087495A4 (en) * 2013-12-23 2017-08-23 Intel Corporation Integrated component interconnect
MA40433A (fr) 2014-07-21 2017-06-14 Sevecom Spa Émulsion en poudre pour aliments pour animaux
EA201790384A1 (ru) 2014-08-15 2017-08-31 Кариофарм Терапевтикс, Инк. Полиморфы селинексора
MA43529A (fr) 2015-12-31 2018-11-07 Karyopharm Therapeutics Inc Modulateurs de transport nucléaire et leurs utilisations
WO2017117535A1 (en) 2015-12-31 2017-07-06 Karyopharm Therapeutics Inc. Nuclear transport modulators and uses thereof
WO2018098472A1 (en) 2016-11-28 2018-05-31 Karyopharm Therapeutics Inc. Crm1 inhibitors for treating epilepsy
JP7595413B2 (ja) 2016-11-30 2024-12-06 ケース ウエスタン リザーブ ユニバーシティ １５－ｐｇｄｈ阻害剤とコルチコステロイドおよび／またはｔｎｆ阻害剤との組み合わせならびにその使用
EP3576737A4 (en) 2017-02-06 2021-04-21 Case Western Reserve University COMPOSITIONS AND METHODS OF MODULATING THE ACTIVITY OF SHORT CHAIN DEHYDROGENASE
EP3883577A4 (en) 2018-11-21 2022-06-15 Case Western Reserve University COMPOSITIONS AND METHODS FOR MODULATION OF SHORT CHAIN DEHYDROGENASE ACTIVITY
US20200397720A1 (en) * 2019-06-23 2020-12-24 Charles Huntington Gallina Method and formulation for treatment of wounds by new tissue regeneration with reduced trauma and scar tissue formation

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CN1668345A (zh) * 2002-07-16 2005-09-14 先进生物技术公司 创伤敷料
WO2008109887A1 (en) * 2007-03-08 2008-09-12 Biozone Laboratories Inc. Dressing formulations to prevent and reduce scarring

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KR20080016612A (ko) * 2005-06-10 2008-02-21 갈데르마 소시에떼아노님 약물, 필름형성 실리콘 및 하나 이상의 휘발성 용매를포함하는 국소조성물을 기초로 하는 피부를 통한 약물의조절된 방출
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106573055A (zh) * 2014-06-09 2017-04-19 克洛克斯科技公司 基于硅酮的生物光子组合物及其用途
CN106573055B (zh) * 2014-06-09 2021-03-23 广东科洛克生物医药集团有限公司 基于硅酮的生物光子组合物及其用途
US11266685B2 (en) 2014-06-09 2022-03-08 Klox Technologies Inc. Silicone-based biophotonic compositions and uses thereof
CN113453670A (zh) * 2018-09-28 2021-09-28 乔·斯图丁 类固醇和大分子的透孔递送
CN110368498A (zh) * 2019-08-26 2019-10-25 瑞希(重庆)生物科技有限公司 一种促进伤口愈合的制剂及其制备方法

Also Published As

Publication number Publication date
EP2451280A1 (en) 2012-05-16
BR112012001098A2 (pt) 2015-09-01
AU2010271205A1 (en) 2012-02-09
CA2767661A1 (en) 2011-01-13
EP2451280A4 (en) 2012-12-26
WO2011006100A1 (en) 2011-01-13
AR077410A1 (es) 2011-08-24
MX2012000434A (es) 2012-04-11
JP2012532889A (ja) 2012-12-20
US20110009374A1 (en) 2011-01-13

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C53 Correction of patent of invention or patent application
CB02 Change of applicant information

Address after: American California

Applicant after: Moko Therapeutics LLC

Address before: American California

Applicant before: Crescendo Therapeutics LLC

COR Change of bibliographic data

Free format text: CORRECT: APPLICANT; FROM: BIOZONE LAB INC TO: MOKO THERAPEUTICS LLC

C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20120530