CN102458684B - 用于液体雾化的微流体设备 - Google Patents
用于液体雾化的微流体设备 Download PDFInfo
- Publication number
- CN102458684B CN102458684B CN201080026065.3A CN201080026065A CN102458684B CN 102458684 B CN102458684 B CN 102458684B CN 201080026065 A CN201080026065 A CN 201080026065A CN 102458684 B CN102458684 B CN 102458684B
- Authority
- CN
- China
- Prior art keywords
- liquid
- working surface
- equipment
- electrode
- saw
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/005—Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0085—Inhalators using ultrasonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
- A61M15/025—Bubble jet droplet ejection devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0653—Details
- B05B17/0661—Transducer materials
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
- B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
- B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
- B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers
- B05B17/0653—Details
- B05B17/0676—Feeding means
- B05B17/0684—Wicks or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
- A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
- A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
- A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
- A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Preparation (AREA)
- Special Spraying Apparatus (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2009902063 | 2009-05-11 | ||
| AU2009902063A AU2009902063A0 (en) | 2009-05-11 | Microfluidic Apparatus for the Atomisation of a Liquid | |
| PCT/AU2010/000548 WO2010129994A1 (en) | 2009-05-11 | 2010-05-11 | Microfluidic apparatus for the atomisation of a liquid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102458684A CN102458684A (zh) | 2012-05-16 |
| CN102458684B true CN102458684B (zh) | 2016-02-10 |
Family
ID=43084541
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201080026065.3A Expired - Fee Related CN102458684B (zh) | 2009-05-11 | 2010-05-11 | 用于液体雾化的微流体设备 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8991722B2 (enExample) |
| EP (1) | EP2459319B1 (enExample) |
| JP (2) | JP5860395B2 (enExample) |
| CN (1) | CN102458684B (enExample) |
| AU (1) | AU2010246904B2 (enExample) |
| WO (1) | WO2010129994A1 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010129994A1 (en) * | 2009-05-11 | 2010-11-18 | Monash University | Microfluidic apparatus for the atomisation of a liquid |
| WO2013166542A1 (en) * | 2012-05-11 | 2013-11-14 | Monash University | Microfluidic apparatus for the atomisation of a liquid using surface acoustic waves |
| AU2013201383B2 (en) * | 2013-03-01 | 2015-07-02 | Royal Melbourne Institute Of Technology | Atomisation apparatus using surface acoustic wave generaton |
| AU2014336971B2 (en) * | 2013-10-17 | 2020-03-26 | Royal Melbourne Institute Of Technology | Piezoelectric actuation platform |
| US10052431B2 (en) | 2014-06-09 | 2018-08-21 | Ascent Bio-Nano Technologies, Inc. | System for manipulation and sorting of particles |
| GB201420061D0 (en) | 2014-11-11 | 2014-12-24 | Univ Glasgow | Nebulisation of liquids |
| KR20170108057A (ko) * | 2015-01-23 | 2017-09-26 | 윌리엄 탄 | 초음파 증발 요소 |
| GB2536261A (en) * | 2015-03-11 | 2016-09-14 | Linde Ag | An ultrasonic piezo nebuliser |
| GB201509820D0 (en) * | 2015-05-06 | 2015-07-22 | Nicoventures Holdings Ltd | Aerosol delivery device |
| CA2985216C (en) * | 2015-05-13 | 2023-05-09 | Royal Melbourne Institute Of Technology | Acoustic wave microfluidic devices with increased acoustic wave energy utilisation |
| SG10201509280YA (en) * | 2015-11-11 | 2017-06-29 | Singapore Univ Of Tech And Design | Microfluidic particle manipulation |
| GB2548071B (en) * | 2015-12-18 | 2018-05-02 | Thermo Fisher Scient Bremen Gmbh | Liquid sample introduction system and method, for analytical plasma spectrometer |
| AU2017243763B2 (en) * | 2016-03-30 | 2022-10-06 | Philip Morris Products S.A. | Smoking device and method for aerosol-generation |
| US11717845B2 (en) | 2016-03-30 | 2023-08-08 | Altria Client Services Llc | Vaping device and method for aerosol-generation |
| CN111601667B (zh) | 2017-10-26 | 2022-09-16 | 皇家墨尔本理工大学 | 用于声介导的胞内递送的方法和装置 |
| US12275039B2 (en) | 2017-12-11 | 2025-04-15 | Royal Melbourne Institute Of Technology | Apparatus for addressing wells within a microarray plate |
| EP3774073A4 (en) * | 2018-04-05 | 2021-12-22 | Royal Melbourne Institute of Technology | MULTI-SURFACE ACOUSTIC NEBULIZER |
| ES2741373B2 (es) | 2018-08-10 | 2020-10-01 | Inentia Aro Sl | Dispositivo electrónico vestible dispensador de sustancias con elementos intercambiables y método de funcionamiento |
| CN109127180A (zh) * | 2018-09-10 | 2019-01-04 | 河北工业大学 | 一种基于c切铌酸锂晶片实时可控溶胶喷射的装置及方法 |
| CN109781810B (zh) * | 2019-02-26 | 2020-04-10 | 西安交通大学 | 快速检测重金属离子浓度的阵列声表面波纸基微流控系统 |
| CN110093245B (zh) * | 2019-04-28 | 2021-07-16 | 武汉大学 | 一种声表面波液滴激发装置及定点释放肿瘤单细胞的方法 |
| HUE070175T2 (hu) | 2019-06-20 | 2025-05-28 | Shaheen Innovations Holding Ltd | Személyi ultrahangos porlasztó készülék |
| JP7396824B2 (ja) * | 2019-07-02 | 2023-12-12 | 株式会社ディスコ | 超音波水噴射装置 |
| US12233207B2 (en) | 2019-12-15 | 2025-02-25 | Shaheen Innovations Holding Limited | Mist inhaler devices |
| WO2021123869A1 (en) | 2019-12-15 | 2021-06-24 | Shaheen Innovations Holding Limited | Ultrasonic mist inhaler |
| US11730193B2 (en) | 2019-12-15 | 2023-08-22 | Shaheen Innovations Holding Limited | Hookah device |
| US12201144B2 (en) | 2019-12-15 | 2025-01-21 | Shaheen Innovations Holding Limited | Hookah device |
| US11589610B2 (en) | 2019-12-15 | 2023-02-28 | Shaheen Innovations Holding Limited | Nicotine delivery device having a mist generator device and a driver device |
| US12121056B2 (en) | 2019-12-15 | 2024-10-22 | Shaheen Innovations Holding Limited | Hookah device |
| CA3231968A1 (en) | 2019-12-15 | 2021-06-24 | Shaheen Innovations Holding Limited | Mist inhaler devices |
| US11730191B2 (en) | 2019-12-15 | 2023-08-22 | Shaheen Innovations Holding Limited | Hookah device |
| WO2021123866A1 (en) | 2019-12-15 | 2021-06-24 | Shaheen Innovations Holding Limited | Ultrasonic mist inhaler |
| EP3855949B1 (en) | 2019-12-15 | 2025-05-07 | Shaheen Innovations Holding Limited | Ultrasonic mist inhaler |
| JP7583061B2 (ja) | 2019-12-15 | 2024-11-13 | シャヒーン イノベーションズ ホールディング リミテッド | 超音波ミスト吸入器 |
| US11666713B2 (en) | 2019-12-15 | 2023-06-06 | Shaheen Innovations Holding Limited | Mist inhaler devices |
| WO2021123871A1 (en) | 2019-12-15 | 2021-06-24 | Shaheen Innovations Holding Limited | Ultrasonic mist inhaler |
| JP2023508344A (ja) * | 2019-12-23 | 2023-03-02 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | 収束エアロゾル発生器 |
| JP7646668B2 (ja) * | 2019-12-23 | 2025-03-17 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | 複数の供給要素を備えるエアロゾル発生器 |
| IL298682B1 (en) | 2020-06-01 | 2025-10-01 | Shaheen Innovations Holding Ltd | Infectious disease scanning device |
| KR20230034986A (ko) | 2020-06-01 | 2023-03-10 | 샤힌 이노베이션즈 홀딩 리미티드 | 감염증 스크리닝 시스템 |
| WO2023108316A1 (zh) * | 2021-12-13 | 2023-06-22 | 中国科学院深圳先进技术研究院 | 基于声表面波技术的便携式精准可视化雾化递送设备 |
| US20230188901A1 (en) | 2021-12-15 | 2023-06-15 | Shaheen Innovations Holding Limited | Apparatus for transmitting ultrasonic waves |
| CN119608477A (zh) * | 2023-09-12 | 2025-03-14 | 天津大学 | 基于高频声波的液体处理装置 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030173867A1 (en) * | 2001-03-20 | 2003-09-18 | Pascal Mauchamp | Ultrasonic transducer apparatus |
| US20080084134A1 (en) * | 2004-12-03 | 2008-04-10 | Epson Toyocom Corporation | Surface acoustic wave device |
| JP2008104966A (ja) * | 2006-10-26 | 2008-05-08 | Seiko Epson Corp | 霧化装置、吸引装置 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4049982A (en) * | 1976-08-18 | 1977-09-20 | The United States Of America As Represented By The Secretary Of The Air Force | Elliptical, interdigital transducer |
| DE2811248C3 (de) * | 1978-03-15 | 1981-11-26 | Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart | Flüssigkeitszerstäuber |
| JPS5832618A (ja) | 1981-08-19 | 1983-02-25 | Sony Corp | 電子線硬化性樹脂 |
| US5894841A (en) | 1993-06-29 | 1999-04-20 | Ponwell Enterprises Limited | Dispenser |
| DE69637458T2 (de) * | 1995-08-07 | 2009-03-05 | Omron Healthcare Co., Ltd. | Zerstäubungsvorrichtung und Verfahren die akustische Oberflächenwellen anwenden |
| DE19533297A1 (de) * | 1995-09-08 | 1997-03-13 | Siemens Ag | Dispersiver Unidirektionalwandler für mit akustischen Oberflächenwellen arbeitende Bauelemente |
| US5831492A (en) * | 1995-09-15 | 1998-11-03 | Sawtek Inc. | Weighted tapered spudt saw device |
| US6325475B1 (en) * | 1996-09-06 | 2001-12-04 | Microfab Technologies Inc. | Devices for presenting airborne materials to the nose |
| AU738838B2 (en) | 1996-09-12 | 2001-09-27 | Valentis, Inc. | Compositions and methods for pulmonary gene delivery |
| JP2000233158A (ja) * | 1999-02-12 | 2000-08-29 | Omron Corp | 噴霧装置 |
| US6407650B1 (en) * | 1999-08-27 | 2002-06-18 | Board Of Regents The University Of Texas System | Surface acoustic wave shaping system |
| US6480076B2 (en) * | 2000-12-21 | 2002-11-12 | Trw Inc. | Recessed reflector single phase unidirectional transducer |
| JP2004266632A (ja) * | 2003-03-03 | 2004-09-24 | Murata Mfg Co Ltd | 弾性表面波装置 |
| JP2006087815A (ja) * | 2004-09-27 | 2006-04-06 | Canon Inc | 噴霧方法および該方法に基づく噴霧装置 |
| CN101137446B (zh) * | 2005-02-11 | 2010-06-09 | 巴特尔纪念研究所 | 电流体动力气雾剂分配装置及喷射方法 |
| US7954730B2 (en) * | 2005-05-02 | 2011-06-07 | Hong Kong Piezo Co. Ltd. | Piezoelectric fluid atomizer apparatuses and methods |
| GB0610090D0 (en) * | 2006-05-20 | 2006-06-28 | Price Robert | Particulate drug compositions and their uses |
| JP4898566B2 (ja) * | 2006-07-13 | 2012-03-14 | キヤノン株式会社 | 薬剤吐出制御方法および薬剤吐出装置 |
| JP2008073570A (ja) * | 2006-09-19 | 2008-04-03 | Seiko Epson Corp | 霧化器、吸引装置 |
| JP4915567B2 (ja) * | 2006-10-26 | 2012-04-11 | パナソニック株式会社 | 弾性表面波霧化装置 |
| EP1952896B1 (en) * | 2007-02-01 | 2012-11-07 | EP Systems SA | Droplet dispenser |
| US7891580B2 (en) * | 2008-04-30 | 2011-02-22 | S.C. Johnson & Son, Inc. | High volume atomizer for common consumer spray products |
| WO2010129994A1 (en) | 2009-05-11 | 2010-11-18 | Monash University | Microfluidic apparatus for the atomisation of a liquid |
-
2010
- 2010-05-11 WO PCT/AU2010/000548 patent/WO2010129994A1/en not_active Ceased
- 2010-05-11 EP EP10774423.7A patent/EP2459319B1/en not_active Not-in-force
- 2010-05-11 AU AU2010246904A patent/AU2010246904B2/en not_active Ceased
- 2010-05-11 CN CN201080026065.3A patent/CN102458684B/zh not_active Expired - Fee Related
- 2010-05-11 US US13/318,976 patent/US8991722B2/en not_active Expired - Fee Related
- 2010-05-11 JP JP2012510069A patent/JP5860395B2/ja not_active Expired - Fee Related
-
2015
- 2015-07-24 JP JP2015146931A patent/JP2016000209A/ja active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030173867A1 (en) * | 2001-03-20 | 2003-09-18 | Pascal Mauchamp | Ultrasonic transducer apparatus |
| US20080084134A1 (en) * | 2004-12-03 | 2008-04-10 | Epson Toyocom Corporation | Surface acoustic wave device |
| JP2008104966A (ja) * | 2006-10-26 | 2008-05-08 | Seiko Epson Corp | 霧化装置、吸引装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010246904B2 (en) | 2015-08-20 |
| EP2459319A4 (en) | 2013-12-04 |
| JP2016000209A (ja) | 2016-01-07 |
| WO2010129994A1 (en) | 2010-11-18 |
| JP5860395B2 (ja) | 2016-02-16 |
| CN102458684A (zh) | 2012-05-16 |
| EP2459319B1 (en) | 2015-01-21 |
| AU2010246904A1 (en) | 2011-12-01 |
| JP2012525944A (ja) | 2012-10-25 |
| US20120187209A1 (en) | 2012-07-26 |
| EP2459319A1 (en) | 2012-06-06 |
| US8991722B2 (en) | 2015-03-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102458684B (zh) | 用于液体雾化的微流体设备 | |
| Alvarez et al. | Rapid generation of protein aerosols and nanoparticles via surface acoustic waveatomization | |
| RU2446895C2 (ru) | Ультразвуковой распылитель жидкости | |
| JP6537982B2 (ja) | 表面弾性波生成を用いた霧化装置 | |
| US11771846B2 (en) | Nebulisation of liquids | |
| US6601581B1 (en) | Method and device for ultrasound drug delivery | |
| JP2008168222A (ja) | 超音波霧化装置 | |
| AU2019248020B2 (en) | Multi surface acoustic nebuliser | |
| JP2008168223A (ja) | 液体霧化装置及び液体霧化方法 | |
| Tsai et al. | Faraday instability-based micro droplet ejection for inhalation drug delivery | |
| CA3153497A1 (en) | Acoustic nebuliser for delivery of active agents | |
| Vu et al. | Charge-reduced particles via self-propelled electrohydrodynamic atomization for drug delivery applications | |
| WO2013166542A1 (en) | Microfluidic apparatus for the atomisation of a liquid using surface acoustic waves | |
| Greenspan | Ultrasonic and electrohydrodynamic methods for aerosol generation | |
| Tsai et al. | Pocket-sized ultrasonic nebulizer for inhalation drug delivery | |
| Tsai et al. | Ultrasound-driven megahertz Faraday waves for generation of monodisperse micro droplets and applications | |
| Alan et al. | PALM: Integrated Ultrasonically-Actuated platform to deliver uniform aerosol droplets with tuneable diameters | |
| KR20250117401A (ko) | 분무 방법 및 장치 | |
| AU2024261993A1 (en) | Nebulisation method | |
| Yeo et al. | Surface acoustic waves: a new paradigm for driving ultrafast biomicrofluidics | |
| Tsai et al. | MEMS-based multiple fourier-horn silicon ultrasonic atomizer for inhalation drug delivery | |
| Qi | Fundamentals and biomicrofluidic applications of surface acoustic wave atomization |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160210 Termination date: 20170511 |