CN102448493B - 胰岛素抗性疾病的治疗 - Google Patents

胰岛素抗性疾病的治疗 Download PDF

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Publication number
CN102448493B
CN102448493B CN201080023924.3A CN201080023924A CN102448493B CN 102448493 B CN102448493 B CN 102448493B CN 201080023924 A CN201080023924 A CN 201080023924A CN 102448493 B CN102448493 B CN 102448493B
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antibody
antibodies
insulin
human
insulin resistance
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Chinese (zh)
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CN102448493A (zh
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G·A·科卢玛姆
Y·(H)·胡
W·欧阳
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Reproductive Health (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201080023924.3A 2009-04-01 2010-03-30 胰岛素抗性疾病的治疗 Active CN102448493B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16567709P 2009-04-01 2009-04-01
US61/165,677 2009-04-01
PCT/US2010/029280 WO2010114859A1 (en) 2009-04-01 2010-03-30 Treatment of insulin-resistant disorders

Publications (2)

Publication Number Publication Date
CN102448493A CN102448493A (zh) 2012-05-09
CN102448493B true CN102448493B (zh) 2014-04-30

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ID=42229822

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CN201080023924.3A Active CN102448493B (zh) 2009-04-01 2010-03-30 胰岛素抗性疾病的治疗

Country Status (24)

Country Link
US (1) US20100266595A1 (https=)
EP (1) EP2413967A1 (https=)
JP (1) JP5795306B2 (https=)
KR (1) KR101766927B1 (https=)
CN (1) CN102448493B (https=)
AR (1) AR075998A1 (https=)
AU (1) AU2010232692C1 (https=)
BR (1) BRPI1011535A2 (https=)
CA (1) CA2752908A1 (https=)
CL (1) CL2011002416A1 (https=)
CO (1) CO6410313A2 (https=)
CR (1) CR20110552A (https=)
EC (1) ECSP11011429A (https=)
IL (1) IL214745A0 (https=)
MA (1) MA33248B1 (https=)
MX (1) MX347978B (https=)
NZ (1) NZ595005A (https=)
PE (1) PE20120628A1 (https=)
RU (1) RU2537142C2 (https=)
SG (1) SG174891A1 (https=)
TW (1) TWI474833B (https=)
UA (1) UA105384C2 (https=)
WO (1) WO2010114859A1 (https=)
ZA (1) ZA201106076B (https=)

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RU2474588C2 (ru) 2008-05-05 2013-02-10 Новиммун Са Перекрестно-реактивные антитела анти-il-17a/il-17f и способы их применения
US8790642B2 (en) 2008-08-29 2014-07-29 Genentech, Inc. Cross-reactive and bispecific anti-IL-17A/F antibodies
US20120201821A1 (en) 2010-10-25 2012-08-09 Gonzalez Jr Lino Treatment of Gastrointestinal Inflammation and Psoriasis and Asthma
US9117641B2 (en) 2012-10-29 2015-08-25 Perkinelmer Health Sciences, Inc. Direct sample analysis device adapters and methods of using them
ES2804719T3 (es) * 2013-02-04 2021-02-09 Sanofi Sa Formulaciones farmacéuticas estabilizadas de análogos de insulina y/o derivados de insulina
TWI780236B (zh) * 2013-02-04 2022-10-11 法商賽諾菲公司 胰島素類似物及/或胰島素衍生物之穩定化醫藥調配物
MX2016008979A (es) 2014-01-09 2016-10-04 Sanofi Sa Formulaciones farmaceuticas estabilizadas de analogos de insulina y/o derivados de insulina.
AR103173A1 (es) 2014-12-22 2017-04-19 Novarits Ag Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17
US10858427B2 (en) 2017-03-10 2020-12-08 Suzhou Kanova Biopharmaceutical Co., Ltd. Monoclonal antibody against both IL-17A and IL-17F and use of the same

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Also Published As

Publication number Publication date
CL2011002416A1 (es) 2012-04-20
CN102448493A (zh) 2012-05-09
MX347978B (es) 2017-05-22
KR101766927B1 (ko) 2017-08-09
SG174891A1 (en) 2011-11-28
TW201038284A (en) 2010-11-01
JP2012522788A (ja) 2012-09-27
KR20120005483A (ko) 2012-01-16
RU2011144122A (ru) 2013-05-10
MA33248B1 (fr) 2012-05-02
BRPI1011535A2 (pt) 2016-03-29
CA2752908A1 (en) 2010-10-07
IL214745A0 (en) 2011-11-30
EP2413967A1 (en) 2012-02-08
AR075998A1 (es) 2011-05-11
AU2010232692B2 (en) 2016-12-01
PE20120628A1 (es) 2012-05-26
CR20110552A (es) 2011-12-07
JP5795306B2 (ja) 2015-10-14
AU2010232692C1 (en) 2017-06-01
CO6410313A2 (es) 2012-03-30
AU2010232692A1 (en) 2011-09-08
ECSP11011429A (es) 2011-12-30
US20100266595A1 (en) 2010-10-21
MX2011010273A (es) 2011-10-17
NZ595005A (en) 2014-04-30
WO2010114859A1 (en) 2010-10-07
TWI474833B (zh) 2015-03-01
UA105384C2 (ru) 2014-05-12
RU2537142C2 (ru) 2014-12-27
ZA201106076B (en) 2012-11-28

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