CN102423447A - Chinese medicinal composition for preventing and treating hand, foot and mouth disease in children - Google Patents

Chinese medicinal composition for preventing and treating hand, foot and mouth disease in children Download PDF

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CN102423447A
CN102423447A CN2011103783419A CN201110378341A CN102423447A CN 102423447 A CN102423447 A CN 102423447A CN 2011103783419 A CN2011103783419 A CN 2011103783419A CN 201110378341 A CN201110378341 A CN 201110378341A CN 102423447 A CN102423447 A CN 102423447A
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foot
radix
mouth disease
hand
medicinal composition
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CN102423447B (en
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张成河
卜凡涛
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Abstract

The invention relates to a Chinese medicinal composition for preventing and treating hand, foot and mouth disease in children and belongs to the technical field of the traditional Chinese medical science and Chinese medicines. The Chinese medicinal composition is prepared from the following Chinese herbal medicines by weight: 10g of towel gourd vegetable sponge, 30g of rhubarb, 10g of Chinese gall, 35g of common cnidium fruit, 30g of calamine, 25g of salted jellyfish, 5g of wrinkled gianthyssop herb, 4g of gypsum rubrum, 15g of cassia twig, 20g of incised notopterygium rhizome, 18g of heracleum, 15g of clematis root, 10g of bark of oriental variegated coralbean, 8g of fructus amomi, 8g of katsumade galangal seed, 20g of coix seed, 15g of hypericum japonicum, 10g of abrus herb, 12g of borax and 10g of Spanish fly. The Chinese medicinal composition has quick response when used for treating the hand, foot and mouth disease, can take effect in two days, has a good therapeutic effect, and can effectively prevent herpes from ulcerating and relive the pain of the children, and the cure rate reaches over 90 percent; and the Chinese medicinal composition can prevent the hand, foot and mouth disease.

Description

The Chinese medicine composition of a kind of prevention and treatment Hand-Food-Mouth Disease
Technical field
The present invention relates to the Chinese medicine technical field, the Chinese medicine composition of particularly a kind of prevention and treatment Hand-Food-Mouth Disease.
Background technology
Hand-foot-mouth disease is the infectious disease that is caused by enterovirus; Pilosity is born in child below 5 years old; Can cause the herpes at positions such as hands, foot, oral cavity, if but herpes ulceration before this, as easy as rolling off a log infection minority infant can cause complication such as myocarditis, pulmonary edema, AME.If indivedual serious symptom infant PD are fast, cause death.The enterovirus that causes hand-foot-mouth disease has more than 20 kind of type.Only obtain the immunity of this type virus after the infection, other type virus is infected no cross immunity again, also possibly suffer from hand-foot-mouth disease once more after promptly suffering from hand-foot-mouth disease because of infecting other type virus.The adult also might fall ill, and therefore we can say that everyone is a susceptible.Incubation period: be mostly 2-10 days, average 3-5 days.
Hand-foot-mouth disease has characteristics such as epidemic strength is big, infectiousness is very strong, route of transmission complicacy.Virus can be stung the food that gets over through the saliva spittle or the fly that has virus, and via intranasal application, oral infections are given healthy children, also can infect because of directly contacting.Aspect treatment, primary disease is like no complication, and prognosis is generally good, how in a week, to fully recover.The Therapeutic Principle is mainly symptomatic treatment.Can take antiviral drugs and heat-clearing and detoxifying herb and vitamin B, C etc.But patient's intramuscular injection gamma-globulin that complication is arranged.During one's sickness, should strengthen nursing Care, perform oral hygiene.Available normal saline or eliminating cold for resuscitation water are gargled before and after the feed, and food is advisable with liquid and nonirritant food such as semi-fluid.Hand-foot-mouth disease because of can merge myocarditis, encephalitis, meningitis, the property paralysis etc. of speeding.
Primary disease belongs to categories such as the traditional Chinese medical science " hygropyrexia ", " epidemic disease ".The cause of disease is an epidemic disease caused by damp-heat pathogen poison, how because of in accumulate damp and hotly, receive seasonal pathogen outward, stay in lung, spleen, the heart three through forming.Exopathogen is gone into from mouth and nose, invasion and attack lung, spleen two warps, lung governing skin and hair, thus the initial stage see lung more and defend symptom, like heating, watery nasal discharge, cough; Spleen governing limbs is had one's ideas straightened out in mouth, and hand-foot-mouth disease receives heresy and is vesicle, and herpes, ulcer are given birth in dispute.The Chinese medicine primary disease mainly adopts differentiation of symptoms and signs for classification of syndrome, differential diagnosis of diseases by stages, specially just to add and subtract three kinds of basic skills at present.Can up to standard take into account, the effect of mitigation symptoms, the shortening course of disease.But most of Chinese medicine preparation drug effect performances are slow, therapeutic effect is desirable not to the utmost.And hand-foot-mouth disease can only be treated after disease is sent out, and does not have relevant prophylactic agent.
Summary of the invention
The performance of above treatment by Chinese herbs hand-foot-mouth disease drug effect is slow in order to solve, therapeutic effect is desirable not to the utmost, the problem of no prophylactic agent, the invention provides a kind of sick drug effect performance soon, therapeutic effect is good, Chinese medicine composition that can the primary prevention Hand-Food-Mouth Disease.
The present invention realizes through following measure:
The Chinese medicine composition of a kind of prevention and treatment Hand-Food-Mouth Disease, the composition of raw materials used medicine is following:
Retinervus Luffae Fructus 10g, Radix Et Rhizoma Rhei 30g, Galla Chinensis 10g, Fructus Cnidii 35g, Calamina 20g, Umbrella Rhopilema esculenta 8g, Herba Pogostemonis 5g; Mirabilitum crystallina 4g, Ramulus Cinnamomi 15g, Rhizoma Et Radix Notopterygii 20g, Radix Angelicae Pubescentis 18g, Radix Clematidis 15g, Cortex erythrinae 10g, Fructus Amomi 8g; Fructus Amomi Rotundus 8g, Semen Coicis 20g, Herba Hyperici Japonici 15g, Herba Abri 10g, Borax 12g, Mylabris 5g.
Method for preparing: take by weighing Retinervus Luffae Fructus, Radix Et Rhizoma Rhei, Galla Chinensis, Fructus Cnidii, Herba Pogostemonis, Ramulus Cinnamomi, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Clematidis, Cortex erythrinae, Fructus Amomi, Fructus Amomi Rotundus, Semen Coicis, Herba Hyperici Japonici, Herba Abri; Mixed powder is broken into coarse powder, and slow fire boiling is 1 hour in the boiled water of 10 times of weight of adding, filters out filtering residue; Be concentrated into relative density and be 1.25 medicinal liquid; Calamina, Mirabilitum crystallina, Umbrella Rhopilema esculenta, Borax, Mylabris are ground to 800 orders, add in the medicinal liquid, stirring promptly gets.
Retinervus Luffae Fructus: collateral dredging, invigorate blood circulation, dispel the wind.
Radix Et Rhizoma Rhei: attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Detoxifcation
Galla Chinensis: astringe the lung; Hidroschesis; Astringing intestine to stop diarrhea; Controlling nocturnal emission with astringent drugs; Hemostasis; Detoxifcation.
Fructus Cnidii: warming the kidney to invigorate YANG, dampness is dispeled the wind, parasite killing.
Calamina: detoxifcation improving acuity of vision and removing nebula, the antipruritic skin ulcer of holding back of removing dampness.
Umbrella Rhopilema esculenta: heat-clearing and toxic substances removing, the detumescence blood pressure lowering, softening and eliminating sputum, cancer suppressing action is arranged.
Herba Pogostemonis: dispelling summer-heat from superficies of the body; Removing dampness to restore normal function of the stomach.
Mirabilitum crystallina: clearing away heat-fire, sharp key, detumescence.
Ramulus Cinnamomi: diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain.
Rhizoma Et Radix Notopterygii: affection of exogenous wind-cold, lossless, the mimeograph cold-damp numbness of headache, edema due to wind pathogen edema, sore swollen toxin.
Radix Angelicae Pubescentis: expelling wind and dampness; Dispersing cold for relieving pain.
Radix Clematidis: expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, the hypochondriac lump of loosing.
Cortex erythrinae: wind-damp dispelling, the meridian dredging, parasite killing.
Fructus Amomi: the removing dampness appetizing, warming spleen and stopping diarrha, it is antiabortive to regulate the flow of vital energy.
Fructus Amomi Rotundus: the removing dampness painful abdominal mass that disappears, circulation of qi promoting warming middle-JIAO, appetite-stimulating indigestion-relieving.
Semen Coicis: spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal.
Herba Hyperici Japonici: dampness removing jaundice eliminating, heat-clearing and toxic substances removing, promoting blood circulation and detumescence.
Herba Abri: clearing away heat-damp and promoting diuresis, eliminating stasis to stop pain.
Borax: the external heat-clearing and toxic substances removing, detumescence, anticorrosion; Removing heat from the lung and dissipating phlegm for oral administration.
Mylabris: removing blood stasis disappears and gargles, dispersing pathogen accumulation.
Beneficial effect of the present invention: traditional Chinese medicine composition for treating hand-foot-mouth disease curative effect of the present invention is fast, takes effect in two days, and therapeutic effect is good, and cure rate reaches more than 90%, and can effectively prevent the herpes ulceration, and it is painful to reduce children's; And can prevent the morbidity of hand-foot-mouth disease.
The specific embodiment
For a better understanding of the present invention, further specify below in conjunction with specific embodiment.
Embodiment 1:
The Chinese medicine composition of a kind of prevention and treatment Hand-Food-Mouth Disease, the composition of raw materials used medicine is following:
Retinervus Luffae Fructus 10g, Radix Et Rhizoma Rhei 30g, Galla Chinensis 10g, Fructus Cnidii 35g, Calamina 20g, Umbrella Rhopilema esculenta 8g, Herba Pogostemonis 5g; Mirabilitum crystallina 4g, Ramulus Cinnamomi 15g, Rhizoma Et Radix Notopterygii 20g, Radix Angelicae Pubescentis 18g, Radix Clematidis 15g, Cortex erythrinae 10g, Fructus Amomi 8g; Fructus Amomi Rotundus 8g, Semen Coicis 20g, Herba Hyperici Japonici 15g, Herba Abri 10g, Borax 12g, Mylabris 5g.
Method for preparing:
Take by weighing Retinervus Luffae Fructus, Radix Et Rhizoma Rhei, Galla Chinensis, Fructus Cnidii, Herba Pogostemonis, Ramulus Cinnamomi, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Clematidis, Cortex erythrinae, Fructus Amomi, Fructus Amomi Rotundus, Semen Coicis, Herba Hyperici Japonici, Herba Abri; Mixed powder is broken into coarse powder; Slow fire boiling is 1 hour in the boiled water of 10 times of weight of adding; Filter out filtering residue, be concentrated into relative density and be 1.15 medicinal liquid
Calamina, Mirabilitum crystallina, Umbrella Rhopilema esculenta, Borax, Mylabris are ground to 800 orders, add in the medicinal liquid, stirring promptly gets.
The clinical effectiveness experiment:
One, therapeutic effect
1, case is selected
62 of the children's of hand-foot-mouth disease suffer from certain children's hospital, and between age 2-6 year, wherein boy is 69; 43 of girls, the infant pharyngalgia, there are erythra or herpes in positions such as hands, foot, oral cavity; Infant is equally divided into two groups, 31 of every group of infants, no difference of science of statistics between two groups.
2, Therapeutic Method
Wherein agree through infants ' parents for one group, use Chinese medicine composition of the present invention to treat, called after treatment group is taken Chinese medicine composition medicinal liquid 200mL of the present invention every day sooner or later; One group is used hospital's conventional treatments to treat the called after matched group.Sooner or later observe therapeutic outcome twice every day.
3, therapeutic outcome
Treat first day early, treatment group and matched group be with respect to before treating, no significant change.
Treat first day evening, matched group with respect to treatment before, no significant change, the treatment group does not have ache the morning when having 3 infants to feel to swallow food, the appearance of 5 infants are generated heat and are disappeared.
Treat second day early; When having 2 infants to feel to swallow food, do not ached before the treatment matched group; It is not painful before the treatment that the treatment group has 11 infants when feeling to swallow food, and have the herpes of 7 infant handss, foot position shrivelled sign to occur, and all infants heating occurs and disappear.
Treat second day evening; When having 12 infants to feel to swallow food, do not ached before the treatment matched group; 21 infants heating occurs and disappear, but shrivelled sign does not appear in herpes, and treatment was not painful before when the treatment group had 26 infants to feel to swallow food; And have the herpes of 18 infant handss, foot position shrivelled sign to occur, all the infant temperature recovery is normal.
Treat after five days, matched group has 3 infant herpes ulcerations, 6 basic rehabilitations of infant, and 22 infant temperature recoveries are normal, but the herpes of hands, foot, oral area position still exists, and do not disappear fully; Treatment group infant does not have herpes ulceration phenomenon, and 23 infants return to one's perfect health, and 8 infant temperature recoveries are normal, and the herpes of hands, foot, oral area position still exists, and does not disappear fully.
After treating a week, matched group still has 6 not rehabilitations of infant, has 1 infant to develop complications, treatment group infant except that the herpes that 2 masterhands, foot, oral area position are arranged does not disappear fully, the whole rehabilitations of all the other infants.
Two, preventive effect
The hand-foot-mouth disease infant appears in certain kindergarten, with infant classmate of the same class infected possibility is arranged all.Under the prerequisite of obtaining head of a family's agreement, the classmate is divided into two groups, no difference of science of statistics between two groups; One group of classmate does not carry out any preventive measure, and as matched group, another group classmate takes Chinese medicine composition medicinal liquid 100mL of the present invention twice sooner or later; As the prevention group, after 10 days, matched group classmate hand-foot-mouth disease sickness rate is 53%; Prevention group classmate hand-foot-mouth disease sickness rate is merely 8%; It is thus clear that traditional Chinese medical science compositions medicinal liquid of the present invention is worth promoting in the hand-foot-mouth disease prone areas having good effect aspect the morbidity of prevention hand-foot-mouth disease.

Claims (2)

  1. One kind the prevention and the treatment Hand-Food-Mouth Disease Chinese medicine composition, it is characterized in that the composition of raw materials used medicine is following:
    Retinervus Luffae Fructus 10g, Radix Et Rhizoma Rhei 30g, Galla Chinensis 10g, Fructus Cnidii 35g, Calamina 20g, Umbrella Rhopilema esculenta 8g, Herba Pogostemonis 5g; Mirabilitum crystallina 4g, Ramulus Cinnamomi 15g, Rhizoma Et Radix Notopterygii 20g, Radix Angelicae Pubescentis 18g, Radix Clematidis 15g, Cortex erythrinae 10g, Fructus Amomi 8g; Fructus Amomi Rotundus 8g, Semen Coicis 20g, Herba Hyperici Japonici 15g, Herba Abri 10g, Borax 12g, Mylabris 5g.
  2. 2. Chinese medicine composition according to claim 1; It is characterized in that taking by weighing Retinervus Luffae Fructus, Radix Et Rhizoma Rhei, Galla Chinensis, Fructus Cnidii, Herba Pogostemonis, Ramulus Cinnamomi, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Clematidis, Cortex erythrinae, Fructus Amomi, Fructus Amomi Rotundus, Semen Coicis, Herba Hyperici Japonici, Herba Abri; Mixed powder is broken into coarse powder, and slow fire boiling is 1 hour in the boiled water of 10 times of weight of adding, filters out filtering residue; Be concentrated into relative density and be 1.25 medicinal liquid; Calamina, Mirabilitum crystallina, Umbrella Rhopilema esculenta, Borax, Mylabris are ground to 800 orders, add in the medicinal liquid, stirring promptly gets.
CN 201110378341 2011-11-24 2011-11-24 Chinese medicinal composition for preventing and treating hand, foot and mouth disease in children Expired - Fee Related CN102423447B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102920382A (en) * 2012-11-22 2013-02-13 桂林明焕生物科技有限公司 Cleaner towel capable of preventing hand-foot-mouth disease and preparation method of cleaner towel
CN105902887A (en) * 2016-06-05 2016-08-31 葛文农 Traditional Chinese medicine pills for effectively treating hand-foot-and-mouth disease

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101884776A (en) * 2010-07-05 2010-11-17 阚恭勇 Chinese preparation for treating hand-foot-and-mouth diseases

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101884776A (en) * 2010-07-05 2010-11-17 阚恭勇 Chinese preparation for treating hand-foot-and-mouth diseases

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102920382A (en) * 2012-11-22 2013-02-13 桂林明焕生物科技有限公司 Cleaner towel capable of preventing hand-foot-mouth disease and preparation method of cleaner towel
CN105902887A (en) * 2016-06-05 2016-08-31 葛文农 Traditional Chinese medicine pills for effectively treating hand-foot-and-mouth disease

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