CN102423442A - Double-component medicine for treating fatty liver and preparation method thereof - Google Patents
Double-component medicine for treating fatty liver and preparation method thereof Download PDFInfo
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- CN102423442A CN102423442A CN2011104418501A CN201110441850A CN102423442A CN 102423442 A CN102423442 A CN 102423442A CN 2011104418501 A CN2011104418501 A CN 2011104418501A CN 201110441850 A CN201110441850 A CN 201110441850A CN 102423442 A CN102423442 A CN 102423442A
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Abstract
The invention discloses a double-component medicine for treating fatty liver and a preparation method thereof. The invention mainly solves the problem that the existing medicine for treating fatty liver is not suitable for long-term taking and can not simultaneously achieve stable effect, high application safety and small adverse reaction. The double-component medicine disclosed by the invention is prepared from a component A and a component B, wherein the component A is prepared from combined spicebush root extract, rhizoma corydalis extract, pseudo-ginseng powder, radix clematidis extract, black monkshood, eucommia extract and the like; and the component B is prepared from radix rehmanniae preparata extract, safflower extract, radix bupleuri extract, radix asparagi extract, radix ophiopogonis extract, radix cyathulae extract and the like. The invention also provides a preparation method of the double-component medicine. The invention is suitable for long-term taking, and has the advantages of stable effect, high application safety, small adverse reaction and the like.
Description
Technical field
What the present invention relates to is a kind of Chinese medicine composition of treating fatty liver, specifically is meant a kind of two prescription medicines that use Chinese herbal medicine as raw material treatment fatty liver, the invention still further relates to the method for preparing of this medicine.
Background technology
Fatty liver is coerced pain, discomfort with the right side, and fatigue and weakness etc. are main clinical characteristics, belongs to categories such as the traditional Chinese medical science " hypochondriac pain ", " stasis of liver-Q and liver-blood ", " obstruction of the liver-QI ", " gathering ", " expectorant is turbid ", " blood stasis ".Theory of Chinese medical science is thought primary disease stopping in the phlegm-damp, and stasis of blood choke stagnates and is main pathogenesis, how hinders etc. pathogenic because of drinking and eating irregularly, depression of liver-QI, damp-heat accumulation, poisoning.Sick position relates to spleen, stomach, gallbladder mainly liver.Main pathological product is phlegm retention, blood stasis, the stagnation of QI.Characteristic of disease belongs to the deficiency in origin and excess in superficiality card.At this is the deficiency of vital energy, mainly sees deficiency of liver-QI, deficiency of spleen-QI; Be designated as damp and hot, phlegm retention, blood stasis, the stagnation of QI, and the folder of holding concurrently occurs more.Hepatopathy committee of Chinese Chinese medicine association formulated the differentiation of symptoms and signs for classification of syndrome standard of fatty liver in 1992; Be damp and hot middle resistance, stagnation of liver-QI with deficiency of the spleen, the hepatic and renal YIN deficiency and obstruction of collaterals by blood stasis four types; And more with the liver-depression and spleen-insufficiency type patient through the clinical statistics discovery, liver-kidney yin deficiency and obstruction of collaterals by blood stasis type person are less.
Fatty liver is a kind of chronic comprehensive disease, and the course of disease is longer, is difficult for speed more, and prolonged illness must be hindered healthy energy, so reinforcing body resistance also is the very important one side of treatment fatty liver.The treatment of fatty liver should be paid attention to setting upright, and sets upright that medicine relates to QI invigorating, enriches blood, nourishing YIN, YANG invigorating each side.Present clinical blood circulation promoting and blood stasis dispelling, damp eliminatingization are turbid to be the basic skills of treatment fatty liver; Simultaneously also need combine individual patients situation and pathogenic characteristic; The fit applications heat clearing away, regulate the flow of vital energy, reduce phlegm, spleen invigorating, soothing the liver, multiple method of treatment and medicine such as help digestion, can obtain satisfied curative effect.Do not take for a long time but the medicine of existing treatment fatty liver is suitable, and the characteristics stable, safe in utilization, that untoward reaction is little that can't be effective simultaneously.
Summary of the invention
The object of the invention provides and a kind ofly suitable takes for a long time, effect stability, safe in utilization, untoward reaction is little is used to two prescription medicines of treating fatty liver and preparation method thereof.
Realize that technical scheme of the present invention is following: a kind of two prescription medicines that are used to treat fatty liver, said medicine is made up of the prescription A of 5～10 weight portions and the prescription B of 3～9 weight portions,
Said prescription A is by the radix linderae extract; Radix Salviae Miltiorrhizae extract; The Rhizoma Corydalis extract; Radix Notoginseng powder; Radix Clematidis extract; Radix Aconiti Lateralis Preparata; Cortex Eucommiae extract; Radix Achyranthis Bidentatae extract; Radix Bupleuri extract; Rhizoma Chuanxiong extract; Oletum Trogopterori; Margarita powder; The artificial Calculus Bovis; Borneolum Syntheticum; Ganoderma spore powder; Radix Sophorae Flavescentis extract; Oligochitosan; Semen Vitis viniferae extract; Resveratrol extract; Radix Ginseng extract; Herba Epimedii extract; Herba Lysimachiae extract; Herba Hedyotidis Diffusae extract; Herba Scutellariae Barbatae extract and vitamin C are formed
Said prescription B is by the Fructus Crataegi extract; Radix Aucklandiae extract; Radix Astragali extract; Radix Clematidis extract; Fructus Jujubae extract; Radix Angelicae Sinensis extract; Rhizoma Chuanxiong extract; The Radix Paeoniae Rubra extract; Semen Persicae extract; Radix Bupleuri extract; Rhizoma Atractylodis Macrocephalae extract; Rhizoma Alismatis extract; The Fructus Hordei Germinatus extract; Radix Rehmanniae Preparata extract; Flos Carthami extract; The Bulbus Fritillariae Cirrhosae extract; Cortex Eucommiae extract; Fructus Ligustri Lucidi extract; Fructus Lycii extract; The radix linderae extract; Radix Salviae Miltiorrhizae extract; Rhizoma Smilacis Glabrae extract; Rhizoma Gastrodiae extract; Radix Codonopsis extract; The Radix Asparagi extract; Radix Ophiopogonis extract; Radix Cyathulae extract; Cortex Cinnamomi extract; Fructus Schisandrae Chinensis extrat; Oligochitosan is formed.
Further, said prescription A and prescription B are made up of the component of following weight portion,
Prescription A: 1～4 part of radix linderae extract; 1～4 part of Radix Salviae Miltiorrhizae extract; 1～4 part of Rhizoma Corydalis extract; 1～4 part of Radix Notoginseng powder; 1～4 part of Radix Clematidis extract; 1～4 part of Radix Aconiti Lateralis Preparata; 1～4 part of Cortex Eucommiae extract; 1～4 part of Radix Achyranthis Bidentatae extract; 1～4 part of Radix Bupleuri extract; 1～4 part of Rhizoma Chuanxiong extract; 1～4 part of Oletum Trogopterori; 1～4 part of Margarita powder; 1～4 part of artificial Calculus Bovis; 1～4 part of Borneolum Syntheticum; 10～25 parts of Ganoderma spore powders; 4～12 parts of oligochitosans; 2～6 parts of Radix Sophorae Flavescentis extracts; 1～3 part of Semen Vitis viniferae extract; 1～4 part of resveratrol extract; 3～9 parts of Radix Ginseng extracts; 3～9 parts of Herba Epimedii extracts; 5～15 parts of Herba Lysimachiae extracts; 10～30 parts of Herba Hedyotidis Diffusae extracts; 5～15 parts of Herba Scutellariae Barbatae extracts; 1～4 part of vitamin C
Prescription B: 10～30 parts of Fructus Crataegi extracts; 5～15 parts of Radix Aucklandiae extracts; 6～18 parts of Radix Astragali extracts; 3～9 parts of Radix Clematidis extracts; 3～9 parts of Fructus Jujubae extracts; 1～4 part of Radix Angelicae Sinensis extract; 1～4 part of Rhizoma Chuanxiong extract; 2～5 parts of Radix Paeoniae Rubra extracts; 1～4 part in Semen Persicae extract; 1～4 part of Rhizoma Alismatis extract; 3～9 parts of Fructus Hordei Germinatus extracts; 2～6 parts of Radix Rehmanniae Preparata extracts; 1～4 part of Flos Carthami extract; 1～4 part of Bulbus Fritillariae Cirrhosae extract; 2～6 parts of Cortex Eucommiae extract; 3～9 parts of Fructus Ligustri Lucidi extracts; 3～9 parts of Fructus Lycii extracts; 1～4 part of radix linderae extract; 3～9 parts of Fructus Schisandrae Chinensis extrats; 2～6 parts of Rhizoma Atractylodis Macrocephalae extracts; 2～6 parts of Radix Bupleuri extracts; 1～4 part of Radix Salviae Miltiorrhizae extract; 6～18 parts of Rhizoma Smilacis Glabrae extracts; 1～4 part of Rhizoma Gastrodiae extract; 1～4 part of Radix Codonopsis extract; 1～4 part of Radix Asparagi extract; 1～4 part of Radix Ophiopogonis extract; 2～6 parts of Radix Cyathulae extracts; 1～4 part of Cortex Cinnamomi extract; 1～3 part of oligochitosan.
Further, said prescription A and prescription B are made up of the component of following weight portion,
Prescription A: 2 parts of radix linderae extracts; 2 parts of Radix Salviae Miltiorrhizae extracts; 2 parts of Rhizoma Corydalis extracts; 2 parts of Radix Notoginseng powder; 2 parts of Radix Clematidis extracts; 2 parts of Radix Aconiti Lateralis Preparatas; 2 parts of Cortex Eucommiae extract; 2 parts of Radix Achyranthis Bidentatae extracts; 2 parts of Radix Bupleuri extracts; 2 parts of Rhizoma Chuanxiong extracts; 2 parts of Oletum Trogopteroris; 2 parts of Margarita powder; 2 parts of artificial Calculus Boviss; 2 parts of Borneolum Syntheticums; 16 parts of Ganoderma spore powders; 8 parts of oligochitosans; 4 parts of Radix Sophorae Flavescentis extracts; 1 part of Semen Vitis viniferae extract; 2 parts of resveratrol extracts; 6 parts of Radix Ginseng extracts; 6 parts of Herba Epimedii extracts; 10 parts of Herba Lysimachiae extracts; 20 parts of Herba Hedyotidis Diffusae extracts; 10 parts of Herba Scutellariae Barbatae extracts; 2 parts of vitamin Cs
Prescription B: 20 parts of Fructus Crataegi extracts; 10 parts of Radix Aucklandiae extracts; 12 parts of Radix Astragali extracts; 6 parts of Radix Clematidis extracts; 6 parts of Fructus Jujubae extracts; 2 parts of Radix Angelicae Sinensis extracts; 2 parts of Rhizoma Chuanxiong extracts; 3 parts of Radix Paeoniae Rubra extracts; 2 parts in Semen Persicae extract; 2 parts of Rhizoma Alismatis extracts; 6 parts of Fructus Hordei Germinatus extracts; 4 parts of Radix Rehmanniae Preparata extracts; 2 parts of Flos Carthami extracts; 2 parts of Bulbus Fritillariae Cirrhosae extracts; 4 parts of Cortex Eucommiae extract; 6 parts of Fructus Ligustri Lucidi extracts; 6 parts of Fructus Lycii extracts; 2 parts of radix linderae extracts; 6 parts of Fructus Schisandrae Chinensis extrats; 4 parts of Rhizoma Atractylodis Macrocephalae extracts; 4 parts of Radix Bupleuri extracts; 2 parts of Radix Salviae Miltiorrhizae extracts; 12 parts of Rhizoma Smilacis Glabrae extracts; 2 parts of Rhizoma Gastrodiae extracts; 2 parts of Radix Codonopsis extracts; 2 parts of Radix Asparagi extracts; 2 parts of Radix Ophiopogonis extracts; 4 parts of Radix Cyathulae extracts; 2 parts of Cortex Cinnamomi extracts; 1 part of oligochitosan.
The method for preparing of two prescription medicines, mainly form by following steps:
(1) prepares various extracts among prescription A and the prescription B;
(2) all the other each components among prescription A and the prescription B are pulverized respectively;
(3) with each the component mix homogeneously among the prescription A, general ball makes 2～4mm piller, drying;
(4), process granule or add Mel and process honeyed pill with each the component mix homogeneously among the prescription B.
Further, cross 80 mesh sieves in the said step (2) among prescription A and the prescription B behind all the other each component pulverize separately.
For the material that makes extraction is an active substance, said extract obtains through following steps:
The material that (1) will extract is removed impurity;
(2) material that will remove impurity carries out pulverization process;
(3) ratio in 1Kg radix linderae and 10L water is put in it in extraction pot, refluxes 20～30 minutes, obtains extracting solution;
(4), concentrate this extracting solution with extracting solution suction concentration tank;
(5) the spray-dried extract that promptly makes of extracting solution after said the concentrating.
The present invention has the following advantages and beneficial effect:
1, the present invention be combine blood stasis dispelling damp eliminating treatment fatty liver method such as adopt food stagnation removing to mend at all, again to let out cooperate fatty liver is prevented and treated;
2, the present invention have action range, effect stability, safe in utilization, untoward reaction is little, suitable characteristics of taking for a long time;
3, the present invention is the various methods that a kind of material high efficiency extraction effective ingredient is provided, and has not only kept drug effect greatly, and has improved the extraction content of effective ingredient, has reduced production cost.
The specific embodiment
Below in conjunction with embodiment the present invention is done to specify further, but embodiment of the present invention is not limited thereto.
Embodiment 1
At first, obtain the extract of various materials, the extraction step of extract is following:
The material that (1) will extract is removed impurity; Like the radix linderae extract, the medicinal part of radix linderae is taken out;
(2) material that will remove impurity carries out pulverization process; Promptly handle, it is crushed to 20 orders through pulverizer;
(3) ratio in 1Kg material and 10L water is put in it in extraction pot, refluxes 20～30 minutes, obtains extracting solution; Extracting temperature is 100 ℃;
(4) with extracting solution suction concentration tank, concentrate this extracting solution, promptly adopt the conventional method for concentration of the field of Chinese medicines under 90 ℃ of left and right sides conditions, to concentrate this extracting solution;
(5) the spray-dried radix linderae extract that promptly makes of extracting solution after said the concentrating.
Various extracts among prescription A and the prescription B all are to obtain through above method.
Secondly, each component of the non-extract among prescription A and the prescription B is pulverized respectively; Be crushed to its fineness smaller or equal to 80 orders.Can when pulverizing, cross 80 purposes sieve here, just sifted out smaller or equal to 80 purpose components, all the other compositions are proceeded to pulverize.Need pulverized component that Radix Notoginseng powder, Radix Aconiti Lateralis Preparata, Oletum Trogopterori, Margarita powder, artificial Calculus Bovis, Borneolum Syntheticum, Ganoderma spore powder, oligochitosan and vitamin C among the prescription A are arranged in the present embodiment, among the prescription B is oligochitosan.
Moreover; With 2 parts of radix linderae extracts among the prescription A, 2 parts of Radix Salviae Miltiorrhizae extracts, 2 parts of Rhizoma Corydalis extracts, 2 parts of Radix Notoginseng powder, 2 parts of Radix Clematidis extracts, 2 parts of Radix Aconiti Lateralis Preparatas, 2 parts of Cortex Eucommiae extract, 2 parts of Radix Achyranthis Bidentatae extracts, 2 parts of Radix Bupleuri extracts, 2 parts of Rhizoma Chuanxiong extracts, 2 parts of Oletum Trogopteroris, 2 parts of Margarita powder, 2 parts of artificial Calculus Boviss, 2 parts of Borneolum Syntheticums, 16 parts of Ganoderma spore powders, 8 parts of oligochitosans, 4 parts of Radix Sophorae Flavescentis extracts, 1 part of Semen Vitis viniferae extract, 2 parts of resveratrol extracts, 6 parts of Radix Ginseng extracts, 6 parts of Herba Epimedii extracts, 10 parts of Herba Lysimachiae extracts, 20 parts of Herba Hedyotidis Diffusae extracts, 10 parts of Herba Scutellariae Barbatae extracts and 2 parts of mix homogeneously of vitamin C, general ball makes the piller that diameter is 3mm.
At last; With 20 parts of the Fructus Crataegi extracts among the prescription B, 10 parts of Radix Aucklandiae extracts, 12 parts of Radix Astragali extracts, 6 parts of Radix Clematidis extracts, 6 parts of Fructus Jujubae extracts, 2 parts of Radix Angelicae Sinensis extracts, 2 parts of Rhizoma Chuanxiong extracts, 3 parts of Radix Paeoniae Rubra extracts, 2 parts in Semen Persicae extract, 2 parts of Rhizoma Alismatis extracts, 6 parts of Fructus Hordei Germinatus extracts, 4 parts of Radix Rehmanniae Preparata extracts, 2 parts of Flos Carthami extracts, 2 parts of Bulbus Fritillariae Cirrhosae extracts, 4 parts of Cortex Eucommiae extract, 6 parts of Fructus Ligustri Lucidi extracts, 6 parts of Fructus Lycii extracts, 2 parts of radix linderae extracts, 6 parts of Fructus Schisandrae Chinensis extrats, 4 parts of Rhizoma Atractylodis Macrocephalae extracts, 4 parts of Radix Bupleuri extracts, 2 parts of Radix Salviae Miltiorrhizae extracts, 12 parts of Rhizoma Smilacis Glabrae extracts, 2 parts of Rhizoma Gastrodiae extracts, 2 parts of Radix Codonopsis extracts, 2 parts of Radix Asparagi extracts, 2 parts of Radix Ophiopogonis extracts, 4 parts of Radix Cyathulae extracts, 2 parts of Cortex Cinnamomi extracts and 1 part of mix homogeneously of oligochitosan; Adopt conventional method of granulating, through granulations, drying, granulate, be packaged to be every granule that wraps 3g.Perhaps add Mel and process the honeyed pill that weight is 3g.
What the present invention adopted is the piller that prescription A is made into 3mm, and prescription B is made into the honeyed pill of 3g.
Embodiment 2
Prescription A: 3 parts of radix linderae extracts; 2 parts of Radix Salviae Miltiorrhizae extracts; 4 parts of Rhizoma Corydalis extracts; 3 parts of Radix Notoginseng powder; 2 parts of Radix Clematidis extracts; 4 parts of Radix Aconiti Lateralis Preparatas; 3 parts of Cortex Eucommiae extract; 2 parts of Radix Achyranthis Bidentatae extracts; 3 parts of Radix Bupleuri extracts; 2 parts of Rhizoma Chuanxiong extracts; 1 part of Oletum Trogopterori; 4 parts of Margarita powder; 2 parts of artificial Calculus Boviss; 3 parts of Borneolum Syntheticums; 14 parts of Ganoderma spore powders; 10 parts of oligochitosans; 5 parts of Radix Sophorae Flavescentis extracts; 3 parts of Semen Vitis viniferae extracts; 4 parts of resveratrol extracts; 5 parts of Radix Ginseng extracts; 7 parts of Herba Epimedii extracts; 13 parts of Herba Lysimachiae extracts; 23 parts of Herba Hedyotidis Diffusae extracts; 13 parts of Herba Scutellariae Barbatae extracts; 3 parts of vitamin Cs
Prescription B: 10 parts of Fructus Crataegi extracts; 13 parts of Radix Aucklandiae extracts; 7 parts of Radix Astragali extracts; 8 parts of Radix Clematidis extracts; 4 parts of Fructus Jujubae extracts; 4 parts of Radix Angelicae Sinensis extracts; 3 parts of Rhizoma Chuanxiong extracts; 4 parts of Radix Paeoniae Rubra extracts; 2 parts in Semen Persicae extract; 3 parts of Rhizoma Alismatis extracts; 7 parts of Fructus Hordei Germinatus extracts; 3 parts of Radix Rehmanniae Preparata extracts; 4 parts of Flos Carthami extracts; 2 parts of Bulbus Fritillariae Cirrhosae extracts; 3 parts of Cortex Eucommiae extract; 5 parts of Fructus Ligustri Lucidi extracts; 8 parts of Fructus Lycii extracts; 4 parts of radix linderae extracts; 3 parts of Fructus Schisandrae Chinensis extrats; 3 parts of Rhizoma Atractylodis Macrocephalae extracts; 5 parts of Radix Bupleuri extracts; 2 parts of Radix Salviae Miltiorrhizae extracts; 15 parts of Rhizoma Smilacis Glabrae extracts; 3 parts of Rhizoma Gastrodiae extracts; 1 part of Radix Codonopsis extract; 4 parts of Radix Asparagi extracts; 3 parts of Radix Ophiopogonis extracts; 5 parts of Radix Cyathulae extracts; 3 parts of Cortex Cinnamomi extracts; 3 parts of oligochitosans.
Embodiment 3
Prescription A: 1 part of radix linderae extract; 3 parts of Radix Salviae Miltiorrhizae extracts; 3 parts of Rhizoma Corydalis extracts; 3 parts of Radix Notoginseng powder; 3 parts of Radix Clematidis extracts; 2 parts of Radix Aconiti Lateralis Preparatas; 3 parts of Cortex Eucommiae extract; 4 parts of Radix Achyranthis Bidentatae extracts; 1 part of Radix Bupleuri extract; 3 parts of Rhizoma Chuanxiong extracts; 2 parts of Oletum Trogopteroris; 3 parts of Margarita powder; 4 parts of artificial Calculus Boviss; 1 part of Borneolum Syntheticum; 20 parts of Ganoderma spore powders; 8 parts of oligochitosans; 5 parts of Radix Sophorae Flavescentis extracts; 3 parts of Semen Vitis viniferae extracts; 2 parts of resveratrol extracts; 4 parts of Radix Ginseng extracts; 5 parts of Herba Epimedii extracts; 12 parts of Herba Lysimachiae extracts; 13 parts of Herba Hedyotidis Diffusae extracts; 11 parts of Herba Scutellariae Barbatae extracts; 4 parts of vitamin Cs
Prescription B: 27 parts of Fructus Crataegi extracts; 14 parts of Radix Aucklandiae extracts; 10 parts of Radix Astragali extracts; 4 parts of Radix Clematidis extracts; 7 parts of Fructus Jujubae extracts; 3 parts of Radix Angelicae Sinensis extracts; 2 parts of Rhizoma Chuanxiong extracts; 3 parts of Radix Paeoniae Rubra extracts; 4 parts in Semen Persicae extract; 3 parts of Rhizoma Alismatis extracts; 5 parts of Fructus Hordei Germinatus extracts; 5 parts of Radix Rehmanniae Preparata extracts; 4 parts of Flos Carthami extracts; 3 parts of Bulbus Fritillariae Cirrhosae extracts; 4 parts of Cortex Eucommiae extract; 6 parts of Fructus Ligustri Lucidi extracts; 5 parts of Fructus Lycii extracts; 2 parts of radix linderae extracts; 7 parts of Fructus Schisandrae Chinensis extrats; 5 parts of Rhizoma Atractylodis Macrocephalae extracts; 4 parts of Radix Bupleuri extracts; 3 parts of Radix Salviae Miltiorrhizae extracts; 16 parts of Rhizoma Smilacis Glabrae extracts; 1 part of Rhizoma Gastrodiae extract; 2 parts of Radix Codonopsis extracts; 4 parts of Radix Asparagi extracts; 3 parts of Radix Ophiopogonis extracts; 4 parts of Radix Cyathulae extracts; 3 parts of Cortex Cinnamomi extracts; 2 parts of oligochitosans.
Instructions of taking:
Get 1～3 of the honeyed pill that makes according to prescription B, use the eliminating cold for resuscitation broken off by water flush; Get the piller 5～10g that makes according to prescription A again, B is used with prescription, every day three times, takes 3 months.
Detection method is following:
Select 104 Patients with Fatty Liver, and let it take the product that makes according to the present invention.Taking dose is: pill 5～10g that prescription A makes, 1～3 of the honeyed pill that prescription B makes.1～3 of the honeyed pill that at first prescription B is made is used the eliminating cold for resuscitation broken off by water flush, cooks tea and drinks, and the while is used with piller 5～10g that prescription A makes, and every day three times, takes 6 months.Concrete consumption when taking is confirmed according to patient's situation.
Its testing result is: obvious effective rate reaches 76%, and total effective rate reaches 89%.And through detect to find the present invention and blood stasis dispelling damp eliminating, food stagnation removing mend method such as let out cooperatively interact can be effectively lipotropic at all; Have action range, effect stability, safe in utilization, untoward reaction is little, suitable characteristics of taking for a long time, has wide application and DEVELOPMENT PROSPECT.
According to above scheme, just can well realize the present invention.
Claims (6)
1. the two prescription medicines that are used to treat fatty liver is characterized in that, said medicine is made up of the prescription A of 5～10 weight portions and the prescription B of 3～9 weight portions,
Said prescription A is by the radix linderae extract; Radix Salviae Miltiorrhizae extract; The Rhizoma Corydalis extract; Radix Notoginseng powder; Radix Clematidis extract; Radix Aconiti Lateralis Preparata; Cortex Eucommiae extract; Radix Achyranthis Bidentatae extract; Radix Bupleuri extract; Rhizoma Chuanxiong extract; Oletum Trogopterori; Margarita powder; The artificial Calculus Bovis; Borneolum Syntheticum; Ganoderma spore powder; Radix Sophorae Flavescentis extract; Oligochitosan; Semen Vitis viniferae extract; Resveratrol extract; Radix Ginseng extract; Herba Epimedii extract; Herba Lysimachiae extract; Herba Hedyotidis Diffusae extract; Herba Scutellariae Barbatae extract and vitamin C are formed
Said prescription B is by the Fructus Crataegi extract; Radix Aucklandiae extract; Radix Astragali extract; Radix Clematidis extract; Fructus Jujubae extract; Radix Angelicae Sinensis extract; Rhizoma Chuanxiong extract; The Radix Paeoniae Rubra extract; Semen Persicae extract; Radix Bupleuri extract; Rhizoma Atractylodis Macrocephalae extract; Rhizoma Alismatis extract; The Fructus Hordei Germinatus extract; Radix Rehmanniae Preparata extract; Flos Carthami extract; The Bulbus Fritillariae Cirrhosae extract; Cortex Eucommiae extract; Fructus Ligustri Lucidi extract; Fructus Lycii extract; The radix linderae extract; Radix Salviae Miltiorrhizae extract; Rhizoma Smilacis Glabrae extract; Rhizoma Gastrodiae extract; Radix Codonopsis extract; The Radix Asparagi extract; Radix Ophiopogonis extract; Radix Cyathulae extract; Cortex Cinnamomi extract; Fructus Schisandrae Chinensis extrat; Oligochitosan is formed.
2. a kind of two prescription medicines that are used to treat fatty liver according to claim 1 is characterized in that said prescription A and prescription B are made up of the component of following weight portion,
Prescription A: 1～4 part of radix linderae extract; 1～4 part of Radix Salviae Miltiorrhizae extract; 1～4 part of Rhizoma Corydalis extract; 1～4 part of Radix Notoginseng powder; 1～4 part of Radix Clematidis extract; 1～4 part of Radix Aconiti Lateralis Preparata; 1～4 part of Cortex Eucommiae extract; 1～4 part of Radix Achyranthis Bidentatae extract; 1～4 part of Radix Bupleuri extract; 1～4 part of Rhizoma Chuanxiong extract; 1～4 part of Oletum Trogopterori; 1～4 part of Margarita powder; 1～4 part of artificial Calculus Bovis; 1～4 part of Borneolum Syntheticum; 10～25 parts of Ganoderma spore powders; 4～12 parts of oligochitosans; 2～6 parts of Radix Sophorae Flavescentis extracts; 1～3 part of Semen Vitis viniferae extract; 1～4 part of resveratrol extract; 3～9 parts of Radix Ginseng extracts; 3～9 parts of Herba Epimedii extracts; 5～15 parts of Herba Lysimachiae extracts; 10～30 parts of Herba Hedyotidis Diffusae extracts; 5～15 parts of Herba Scutellariae Barbatae extracts; 1～4 part of vitamin C
Prescription B: 10～30 parts of Fructus Crataegi extracts; 5～15 parts of Radix Aucklandiae extracts; 6～18 parts of Radix Astragali extracts; 3～9 parts of Radix Clematidis extracts; 3～9 parts of Fructus Jujubae extracts; 1～4 part of Radix Angelicae Sinensis extract; 1～4 part of Rhizoma Chuanxiong extract; 2～5 parts of Radix Paeoniae Rubra extracts; 1～4 part in Semen Persicae extract; 1～4 part of Rhizoma Alismatis extract; 3～9 parts of Fructus Hordei Germinatus extracts; 2～6 parts of Radix Rehmanniae Preparata extracts; 1～4 part of Flos Carthami extract; 1～4 part of Bulbus Fritillariae Cirrhosae extract; 2～6 parts of Cortex Eucommiae extract; 3～9 parts of Fructus Ligustri Lucidi extracts; 3～9 parts of Fructus Lycii extracts; 1～4 part of radix linderae extract; 3～9 parts of Fructus Schisandrae Chinensis extrats; 2～6 parts of Rhizoma Atractylodis Macrocephalae extracts; 2～6 parts of Radix Bupleuri extracts; 1～4 part of Radix Salviae Miltiorrhizae extract; 6～18 parts of Rhizoma Smilacis Glabrae extracts; 1～4 part of Rhizoma Gastrodiae extract; 1～4 part of Radix Codonopsis extract; 1～4 part of Radix Asparagi extract; 1～4 part of Radix Ophiopogonis extract; 2～6 parts of Radix Cyathulae extracts; 1～4 part of Cortex Cinnamomi extract; 1～3 part of oligochitosan.
3. a kind of two prescription medicines that are used to treat fatty liver according to claim 2 is characterized in that said prescription A and prescription B are made up of the component of following weight portion,
Prescription A: 2 parts of radix linderae extracts; 2 parts of Radix Salviae Miltiorrhizae extracts; 2 parts of Rhizoma Corydalis extracts; 2 parts of Radix Notoginseng powder; 2 parts of Radix Clematidis extracts; 2 parts of Radix Aconiti Lateralis Preparatas; 2 parts of Cortex Eucommiae extract; 2 parts of Radix Achyranthis Bidentatae extracts; 2 parts of Radix Bupleuri extracts; 2 parts of Rhizoma Chuanxiong extracts; 2 parts of Oletum Trogopteroris; 2 parts of Margarita powder; 2 parts of artificial Calculus Boviss; 2 parts of Borneolum Syntheticums; 16 parts of Ganoderma spore powders; 8 parts of oligochitosans; 4 parts of Radix Sophorae Flavescentis extracts; 1 part of Semen Vitis viniferae extract; 2 parts of resveratrol extracts; 6 parts of Radix Ginseng extracts; 6 parts of Herba Epimedii extracts; 10 parts of Herba Lysimachiae extracts; 20 parts of Herba Hedyotidis Diffusae extracts; 10 parts of Herba Scutellariae Barbatae extracts; 2 parts of vitamin Cs
Prescription B: 20 parts of Fructus Crataegi extracts; 10 parts of Radix Aucklandiae extracts; 12 parts of Radix Astragali extracts; 6 parts of Radix Clematidis extracts; 6 parts of Fructus Jujubae extracts; 2 parts of Radix Angelicae Sinensis extracts; 2 parts of Rhizoma Chuanxiong extracts; 3 parts of Radix Paeoniae Rubra extracts; 2 parts in Semen Persicae extract; 2 parts of Rhizoma Alismatis extracts; 6 parts of Fructus Hordei Germinatus extracts; 4 parts of Radix Rehmanniae Preparata extracts; 2 parts of Flos Carthami extracts; 2 parts of Bulbus Fritillariae Cirrhosae extracts; 4 parts of Cortex Eucommiae extract; 6 parts of Fructus Ligustri Lucidi extracts; 6 parts of Fructus Lycii extracts; 2 parts of radix linderae extracts; 6 parts of Fructus Schisandrae Chinensis extrats; 4 parts of Rhizoma Atractylodis Macrocephalae extracts; 4 parts of Radix Bupleuri extracts; 2 parts of Radix Salviae Miltiorrhizae extracts; 12 parts of Rhizoma Smilacis Glabrae extracts; 2 parts of Rhizoma Gastrodiae extracts; 2 parts of Radix Codonopsis extracts; 2 parts of Radix Asparagi extracts; 2 parts of Radix Ophiopogonis extracts; 4 parts of Radix Cyathulae extracts; 2 parts of Cortex Cinnamomi extracts; 1 part of oligochitosan.
4. be used to treat the method for preparing of two prescription medicines of fatty liver described in the claim 1～3, it is characterized in that, mainly form by following steps:
(1) prepares various extracts among prescription A and the prescription B;
(2) all the other each components among prescription A and the prescription B are pulverized respectively;
(3) with each the component mix homogeneously among the prescription A, general ball makes 2～4mm piller, drying;
(4), process granule or add Mel and process honeyed pill with each the component mix homogeneously among the prescription B.
5. the method for preparing that is used to treat two prescription medicines of fatty liver according to claim 4 is characterized in that, mistake 80 mesh sieves behind all the other each component pulverize separately among prescription A and the prescription B in the said step (2).
6. according to claim 4 or the 5 described method for preparinies that are used to treat two prescription medicines of fatty liver, it is characterized in that said extract obtains through following steps:
The material that (1) will extract is removed impurity;
(2) material that will remove impurity carries out pulverization process;
(3) ratio in 1Kg material and 10L water is put in it in extraction pot, refluxes 20～30 minutes, obtains extracting solution;
(4), concentrate this extracting solution with extracting solution suction concentration tank;
(5) the spray-dried extract that promptly makes of extracting solution after said the concentrating.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102641391A (en) * | 2012-04-23 | 2012-08-22 | 刘天岐 | Chinese wolfberry fruit fat reducing and liver nourishing pill |
| CN103599295A (en) * | 2013-11-19 | 2014-02-26 | 太和县中医院 | Traditional Chinese medicine for treating fatty liver |
| CN103845446A (en) * | 2014-03-05 | 2014-06-11 | 张心昱 | Traditional Chinese medicine for regulating liver function |
| CN104274652A (en) * | 2014-10-28 | 2015-01-14 | 合肥丰瑞隆生物科技有限公司 | Traditional Chinese medicine for treating fatty liver |
| CN104382990A (en) * | 2014-11-21 | 2015-03-04 | 江苏鹏鹞药业有限公司 | Composition of herba epimedii, eucommia ulmoides and salviae miltiorrhizae and application of composition |
| CN113717295A (en) * | 2021-09-28 | 2021-11-30 | 遵义医科大学 | Eucommia acidic polysaccharide, extraction method and application of eucommia acidic polysaccharide in preparation of medicine for treating fatty liver |
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| CN102058843A (en) * | 2010-11-24 | 2011-05-18 | 荣成市港圆抽纱制品有限公司 | Chinese medicine composition for treating fatty liver |
| CN102233119A (en) * | 2010-05-08 | 2011-11-09 | 博安兄弟制药（中国）有限公司 | Traditional Chinese medicine composition for treating fatty liver and preparation method thereof |
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| CN1907462A (en) * | 2006-08-07 | 2007-02-07 | 张庆存 | Traditional Chinese medicine composition for treating hepatitis and fatty liver |
| CN102233119A (en) * | 2010-05-08 | 2011-11-09 | 博安兄弟制药（中国）有限公司 | Traditional Chinese medicine composition for treating fatty liver and preparation method thereof |
| CN102058843A (en) * | 2010-11-24 | 2011-05-18 | 荣成市港圆抽纱制品有限公司 | Chinese medicine composition for treating fatty liver |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102641391A (en) * | 2012-04-23 | 2012-08-22 | 刘天岐 | Chinese wolfberry fruit fat reducing and liver nourishing pill |
| CN103599295A (en) * | 2013-11-19 | 2014-02-26 | 太和县中医院 | Traditional Chinese medicine for treating fatty liver |
| CN103599295B (en) * | 2013-11-19 | 2016-02-10 | 太和县中医院 | A kind of Chinese medicine for the treatment of fatty liver |
| CN103845446A (en) * | 2014-03-05 | 2014-06-11 | 张心昱 | Traditional Chinese medicine for regulating liver function |
| CN104274652A (en) * | 2014-10-28 | 2015-01-14 | 合肥丰瑞隆生物科技有限公司 | Traditional Chinese medicine for treating fatty liver |
| CN104382990A (en) * | 2014-11-21 | 2015-03-04 | 江苏鹏鹞药业有限公司 | Composition of herba epimedii, eucommia ulmoides and salviae miltiorrhizae and application of composition |
| CN113717295A (en) * | 2021-09-28 | 2021-11-30 | 遵义医科大学 | Eucommia acidic polysaccharide, extraction method and application of eucommia acidic polysaccharide in preparation of medicine for treating fatty liver |
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| CN102423442B (en) | 2014-06-18 |
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Denomination of invention: A kind of double-group medicine for treating fatty liver and preparation method thereof Effective date of registration: 20220808 Granted publication date: 20140618 Pledgee: Bank of China Co., Ltd. Emeishan Sub-branch Pledgor: EMEISHAN HONGSHENG PHARMACEUTICAL CO.,LTD. Registration number: Y2022980012099 |