CN102408973A - Rhizoma polygonati health wine and preparation method thereof - Google Patents
Rhizoma polygonati health wine and preparation method thereof Download PDFInfo
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- CN102408973A CN102408973A CN2011101925932A CN201110192593A CN102408973A CN 102408973 A CN102408973 A CN 102408973A CN 2011101925932 A CN2011101925932 A CN 2011101925932A CN 201110192593 A CN201110192593 A CN 201110192593A CN 102408973 A CN102408973 A CN 102408973A
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- 235000014101 wine Nutrition 0.000 title claims abstract description 43
- 238000002360 preparation method Methods 0.000 title claims abstract description 20
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 30
- 235000019991 rice wine Nutrition 0.000 claims abstract description 19
- 241000222336 Ganoderma Species 0.000 claims abstract description 16
- 244000241838 Lycium barbarum Species 0.000 claims abstract description 16
- 235000015459 Lycium barbarum Nutrition 0.000 claims abstract description 16
- 235000015468 Lycium chinense Nutrition 0.000 claims abstract description 15
- 238000000034 method Methods 0.000 claims abstract description 10
- 238000000108 ultra-filtration Methods 0.000 claims abstract description 8
- 230000001737 promoting effect Effects 0.000 claims description 37
- 108010064696 N,O-diacetylmuramidase Proteins 0.000 claims description 8
- 241000209094 Oryza Species 0.000 claims description 5
- 235000007164 Oryza sativa Nutrition 0.000 claims description 5
- 235000009566 rice Nutrition 0.000 claims description 5
- 241000235342 Saccharomycetes Species 0.000 claims description 3
- 238000000855 fermentation Methods 0.000 claims description 3
- 230000004151 fermentation Effects 0.000 claims description 3
- 241000411851 herbal medicine Species 0.000 claims description 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract description 5
- 238000007789 sealing Methods 0.000 abstract 1
- 238000002791 soaking Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- 239000003814 drug Substances 0.000 description 6
- 150000004676 glycans Chemical class 0.000 description 6
- 229920001282 polysaccharide Polymers 0.000 description 5
- 239000005017 polysaccharide Substances 0.000 description 5
- 239000000523 sample Substances 0.000 description 5
- 230000003712 anti-aging effect Effects 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- 231100000987 absorbed dose Toxicity 0.000 description 3
- 230000002929 anti-fatigue Effects 0.000 description 3
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- 238000000605 extraction Methods 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 230000000259 anti-tumor effect Effects 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 230000023852 carbohydrate metabolic process Effects 0.000 description 2
- 235000021256 carbohydrate metabolism Nutrition 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 229910021653 sulphate ion Inorganic materials 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- 241000186000 Bifidobacterium Species 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 229920002306 Glycocalyx Polymers 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 241000234280 Liliaceae Species 0.000 description 1
- 206010059013 Nocturnal emission Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- PYKYMHQGRFAEBM-UHFFFAOYSA-N anthraquinone Natural products CCC(=O)c1c(O)c2C(=O)C3C(C=CC=C3O)C(=O)c2cc1CC(=O)OC PYKYMHQGRFAEBM-UHFFFAOYSA-N 0.000 description 1
- 150000004056 anthraquinones Chemical class 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 239000003212 astringent agent Substances 0.000 description 1
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- 239000012153 distilled water Substances 0.000 description 1
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- 235000019441 ethanol Nutrition 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002213 flavones Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 210000004517 glycocalyx Anatomy 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 230000002218 hypoglycaemic effect Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
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- 238000002156 mixing Methods 0.000 description 1
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- 231100000957 no side effect Toxicity 0.000 description 1
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- 230000000144 pharmacologic effect Effects 0.000 description 1
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- 238000010298 pulverizing process Methods 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
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- 210000002784 stomach Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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- 238000009333 weeding Methods 0.000 description 1
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a preparation method of a rhizoma polygonati health wine. The preparation method is characterized by proportionally sealing and soaking rhizoma polygonati, fructus rosae laevigatae, barbary wolfberry fruit, lucid ganoderma and herba epimedii in rice wine with alcohol content being below 40%(v/v) for 3 months and obtaining the rhizoma polygonati health wine through ultrafiltration and filling. The invention also provides the rhizoma polygonati health wine prepared by the method. The active components of rhizoma polygonati in the rhizoma polygonati health wine have higher solubility and are easy to absorb by human body. Meanwhile, the rhizoma polygonati health wine has longer shelf life.
Description
Technical field
The present invention relates to the health promoting wine field, relate in particular to a kind of preparation method of sealwort health promoting wine and the sealwort health promoting wine that obtains by this method.
Background technology
Sealwort is a Liliaceae Polygonatum plant, about 40 kinds of the whole world, and China has 35 kinds." Chinese pharmacopoeia version in 2010 record three kinds of big sealwort, Yunnan sealwort and David's-harps are arranged.Mainly contain materials such as polysaccharide, glycan, flavones, anthraquinone, saponin(e, xylogen, vegeto-alkali and amino acid in the sealwort.Modern pharmacological research is found: sealwort have tonifying kidney and benefiting sperm, nourshing Yin and drynsessmoistening prescription, anti-ageing, antifatigue, anti-oxidant, improve immunizing power, lipopenicillinase, hypoglycemic, effect such as prevention of arterial is atherosis.
Existing sealwort health promoting wine generally perhaps directly extracts through the extraction of carrying out glucide after the sealwort biology is cut into slices, processes health promoting wine then with behind the white spirit mixing.There is following problem in it: sealwort solubleness and stability in liquor is all lower, and effective constituent (for example polysaccharide material) is difficult to stripping on the one hand, and the effective absorbed dose of human body is less; On the other hand, sealwort is unstable, causes the quality guaranteed period of product shorter, and it is lower by the effective absorbed dose of human body.
Summary of the invention
The invention solves and exist effective constituent in the sealwort health promoting wine to be difficult to stripping in the prior art to cause human body to be difficult to a large amount of technical problems of lacking that absorb with the quality guaranteed period.
The invention provides a kind of preparation method of sealwort health promoting wine, comprise sealwort, Fruit of Cherokee Rose, wolfberry fruit, glossy ganoderma, Herba Epimedii are sealed in the rice wine that is soaked in below 40 ° 3 months in proportion, obtain said sealwort health promoting wine after ultrafiltration then, the can.
The present invention also provides a kind of sealwort health promoting wine, and said sealwort health promoting wine is obtained by the preparation method of providing of the present invention.
The preparation method of sealwort health promoting wine provided by the invention; Through sealwort, Fruit of Cherokee Rose, wolfberry fruit, glossy ganoderma, Herba Epimedii being sealed in proportion in the rice wine that is soaked in below 40 °; The number of degrees through to rice wine are suitably selected, and through adding Fruit of Cherokee Rose, wolfberry fruit, glossy ganoderma, Herba Epimedii, can make the solubleness of the effective constituent in the sealwort reach the highest; Thereby effectively stripping is easily absorbed by the body.In addition; Through adding Fruit of Cherokee Rose, wolfberry fruit, glossy ganoderma, Herba Epimedii; The synergy of each component and sealwort makes sealwort health promoting wine of the present invention have antifatigue, anti-ageing, antitumor, balanced fat carbohydrate metabolism, mediator's body immunity function and negative and positive simultaneously with the effect of mending.
Embodiment
The invention provides a kind of preparation method of sealwort health promoting wine, comprise sealwort, Fruit of Cherokee Rose, wolfberry fruit, glossy ganoderma, Herba Epimedii are sealed in the rice wine that is soaked in below 40 ° 3 months in proportion, obtain said sealwort health promoting wine after ultrafiltration then, the can.
Among the present invention; With sealwort is main; Simultaneously through adding Fruit of Cherokee Rose, wolfberry fruit, glossy ganoderma, Herba Epimedii; Through the synergy of each component and sealwort, make sealwort health promoting wine of the present invention have antifatigue, anti-ageing, antitumor, balanced fat carbohydrate metabolism, mediator's body immunity function and negative and positive simultaneously with the effect of mending.
Particularly, sealwort and matrimony vine all have nourishing yin effect, and sealwort and glossy ganoderma have a synergy to anti-ageing, and Fruit of Cherokee Rose has the contract effect of urine, relieving diarrhea with astringents of temperature male wind-supplying kidney, controlling nocturnal emission with astringent drugs, Herba Epimedii kidney-replenishing, strengthening the bones and tendons, wind-damp dispelling.When the medicine of enriching yin makes the male sex produce a large amount of seminal fluid and when hyperfunction, Herba Epimedii is can sensation neural, the indirect excitation sexual desire; Have simultaneously to promote the synthetic of DNA, regulate immunologic function, prevention climacteric hypertension.Therefore, sealwort health promoting wine prescription of the present invention, compatibility is unique, and the adaptation population is wide, effect is obvious.
Among the present invention, be benchmark with the rice wine of 100 weight parts, the consumption of sealwort is the 10-15 weight part, and the consumption of Fruit of Cherokee Rose is the 8-10 weight part, and the consumption of wolfberry fruit is the 5-6 weight part, and the consumption of glossy ganoderma is the 1-1.5 weight part, and the consumption of Herba Epimedii is the 0.5-1 weight part.
More preferably under the situation, be benchmark with the rice wine of 100 weight parts, the consumption of sealwort is 10 weight parts, and the consumption of Fruit of Cherokee Rose is 8 weight parts, and the consumption of wolfberry fruit is 5 weight parts, and the consumption of glossy ganoderma is 1 weight part, and the consumption of Herba Epimedii is 0.5 weight part.
Among the present invention, said rice wine obtains through rice or ground rice are distilled after with saccharomycetes to make fermentation, and wherein said yeast is cultivated through herbal medicine and obtained.Under the preferable case, the number of degrees of said rice wine are for being the 35-38 degree.
Among the present invention, the step of said ultrafiltration, can is conventionally known to one of skill in the art, repeats no more here.
As a kind of preferred implementation of the present invention, method of the present invention also comprises after the ultrafiltration, before the can in the rice wine step of adding N,O-Diacetylmuramidase.Said N,O-Diacetylmuramidase can prolong the quality guaranteed period of said sealwort health promoting wine, and N,O-Diacetylmuramidase can also impel the breeding of intestinal bifidobacteria simultaneously, improves the stomach absorptive function, improves the absorption of human body effect.Total mass with the sealwort health promoting wine is a benchmark, and the content of N,O-Diacetylmuramidase is 0.05wt%.
At last, the invention provides a kind of sealwort health promoting wine, said sealwort health promoting wine is prepared by method provided by the invention.
In the sealwort health promoting wine provided by the invention, all Chinese medicines are the dietotherapeutic plant, and pure natural has no side effect, and meet the regulation of protective foods.
Below in conjunction with embodiment the present invention is further explained.
Embodiment 1
Chinese medicine preparation: sealwort 10kg, Fruit of Cherokee Rose 8 kg, wolfberry fruit 5 kg, glossy ganoderma 1 kg, Herba Epimedii 0.5kg, N,O-Diacetylmuramidase 0.05 kg.
After polished rice being adopted the saccharomycetes to make fermentation of herbal medicine cultivation,, process 35-38 degree pure rice wine through distillation.In proportion above-mentioned Chinese medicine preparation is soaked in sealwort, Fruit of Cherokee Rose, wolfberry fruit, glossy ganoderma and Herba Epimedii in the 35-38 degree rice wine that makes then, the consumption of rice wine is 100kg; Seal 3 months, add N,O-Diacetylmuramidase after the ultrafiltration, can obtains the sealwort health promoting wine S1 of present embodiment.
Embodiment 2
Adopt the sealwort health promoting wine S2 for preparing present embodiment with embodiment 1 identical step, difference is:
Chinese medicine preparation: process sealwort 15kg, Fruit of Cherokee Rose 10 kg, wolfberry fruit 6kg, glossy ganoderma 1.5 kg, Herba Epimedii 1 kg.
Comparative Examples 1
With the sealwort crude drug clean, section, oven dry pulverizing, backflow, filtration, extraction, ferment are heavy, dehydration, drying, add 53 degree liquor then, fully dissolving obtains the sealwort health promoting wine DS1 of this Comparative Examples.
Performance test:
1, polysaccharide content test in the sealwort health promoting wine:
(1) extraction of polysaccharide: accurately take by weighing sealwort health promoting wine sample S1-S2 and each 2.0ml of DS1 places apparatus,Soxhlet's; With 200mL absolute ethyl alcohol extracting 2h weeding of grease soluble components; Extract 3h with 200mL zero(ppm) water Suo Shi again after volatilizing ethanol, suction filtration, filtrating is settled to 250mL in volumetric flask; Draw above-mentioned solution 2.5mL again and be diluted to 25mL, subsequent use.
(2) typical curve: accurately take by weighing be dried to constant weight glucose standard substance 0.1000g in a clean small beaker, with dissolved in distilled water and quantitatively being transferred in the volumetric flask of 100mL, be diluted to scale, shake up.This strength of solution is 1.0mg/mL.The glucose standardized solution 1.0,2.0,3.0,4.0,5.0,6.0mL of drawing 1.0mg/mL are respectively used the zero(ppm) water constant volume in the volumetric flask of 6 50mL, shake up.Draw each 2mL of above-mentioned glucose solution more respectively in 6 brace plug scale test tubes; Other prepares 1 test tube and adds 2mL zero(ppm) water and manage as blank; In above 7 test tubes, respectively add anthrone-sulphate reagent 6mL again; Shake up to be placed on and heat 15min in the boiling water bath, the cooling back is measured absorbancy in the 625nm wavelength with the 1cm cuvette.
(3) sample determination: draw in the step (1) the sample solution 1mL after the dilution respectively in tool plug scale test tube; Respectively add 1mL water; Respectively add anthrone-sulphate reagent 6mL again, shake up to be placed on and heat 15min in the boiling water bath, the cooling back is measured absorbancy in the 625nm wavelength with the 1cm cuvette; The equal replicate(determination) of sample three times goes out polysaccharide content according to regression equation calculation.
2, quality guaranteed period test:
Whether the S1, S2, DS1 sealwort health promoting wine the same terms that (1) will produce preparation simultaneously preserve down, whenever take a sample once at a distance from three months, detect it and contain colony count and exceed standard, and write down the quality guaranteed period of each sealwort health promoting wine sample.
Test result is as shown in table 1.
Table 1
Test result by last table 1 can be found out, adopts the abundant stripping of glycocalix of the sealwort health promoting wine of method preparation provided by the invention, and the effective absorbed dose of human body is higher; Simultaneously, sealwort health promoting wine of the present invention has the long quality guaranteed period.
Above embodiment is merely preferred implementation of the present invention, should be pointed out that to those skilled in the art, and under the prerequisite that does not break away from the principle of the invention, some improvement of having done also should be regarded as protection scope of the present invention.
Claims (8)
1. the preparation method of a sealwort health promoting wine is characterized in that, comprise with sealwort, Fruit of Cherokee Rose, wolfberry fruit, glossy ganoderma, Herba Epimedii seal in proportion be soaked in 40 the degree below rice wine in 3 months, obtain said sealwort health promoting wine after ultrafiltration then, the can.
2. preparation method according to claim 1; It is characterized in that, be benchmark with the rice wine of 100 weight parts, and the consumption of sealwort is the 10-15 weight part; The consumption of Fruit of Cherokee Rose is the 8-10 weight part; The consumption of wolfberry fruit is the 5-6 weight part, and the consumption of glossy ganoderma is the 1-1.5 weight part, and the consumption of Herba Epimedii is the 0.5-1 weight part.
3. preparation method according to claim 2 is characterized in that, is benchmark with the rice wine of 100 weight parts; The consumption of sealwort is 10 weight parts, and the consumption of Fruit of Cherokee Rose is 8 weight parts, and the consumption of wolfberry fruit is 5 weight parts; The consumption of glossy ganoderma is 1 weight part, and the consumption of Herba Epimedii is 0.5 weight part.
4. preparation method according to claim 1 is characterized in that, said rice wine obtains through rice or ground rice are distilled after with saccharomycetes to make fermentation, and wherein said yeast is cultivated through herbal medicine and obtained.
5. according to claim 1 or 4 described preparing methods, it is characterized in that the number of degrees of said rice wine are for being the 35-38 degree.
6. preparation method according to claim 1 is characterized in that, also be included in after the ultrafiltration, before the can in the rice wine step of adding N,O-Diacetylmuramidase.
7. preparation method according to claim 6 is characterized in that, is benchmark with the total mass of sealwort health promoting wine, and the content of N,O-Diacetylmuramidase is 0.05wt%.
8. a sealwort health promoting wine is characterized in that, said sealwort health promoting wine is prepared by each described method of claim 1-7.
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Cited By (10)
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CN103013805A (en) * | 2013-01-09 | 2013-04-03 | 莫雪玲 | Production method of rhizoma polygonati wine |
CN103013804A (en) * | 2013-01-09 | 2013-04-03 | 莫雪玲 | Rhizoma polygonati wine |
CN103041167A (en) * | 2013-01-18 | 2013-04-17 | 彭学川 | Healthcare therapeutic composition for middle and old ages |
CN104547523A (en) * | 2014-12-31 | 2015-04-29 | 贵州泰尔医药研究所 | Medicine for enhancing immunity and preparation method thereof |
CN104738250A (en) * | 2015-04-21 | 2015-07-01 | 徐伟明 | Three-high-disease prevention/lowering health tea and preparation method thereof |
CN105296287A (en) * | 2015-12-01 | 2016-02-03 | 福鼎市西坑孔家茶业有限公司 | Compound polygonatum sibiricum wine |
CN106318778A (en) * | 2016-08-31 | 2017-01-11 | 沈飞 | Health-care wine containing polygonatum and brewing method of health-care wine |
CN106434219A (en) * | 2016-11-23 | 2017-02-22 | 贺州市杨晋记豆豉有限公司 | Rhizoma polygonati health care wine and brewing method thereof |
CN106722265A (en) * | 2016-10-21 | 2017-05-31 | 南陵县石斛产业协会 | A kind of preparation method of sealwort local flavor sheep lung can |
CN106947671A (en) * | 2017-03-30 | 2017-07-14 | 杭州华东医药集团贵州中药发展有限公司 | A kind of preparation method of safflower glossy ganoderma health-care wine |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN103013805A (en) * | 2013-01-09 | 2013-04-03 | 莫雪玲 | Production method of rhizoma polygonati wine |
CN103013804A (en) * | 2013-01-09 | 2013-04-03 | 莫雪玲 | Rhizoma polygonati wine |
CN103041167A (en) * | 2013-01-18 | 2013-04-17 | 彭学川 | Healthcare therapeutic composition for middle and old ages |
CN104547523A (en) * | 2014-12-31 | 2015-04-29 | 贵州泰尔医药研究所 | Medicine for enhancing immunity and preparation method thereof |
CN104738250A (en) * | 2015-04-21 | 2015-07-01 | 徐伟明 | Three-high-disease prevention/lowering health tea and preparation method thereof |
CN105296287A (en) * | 2015-12-01 | 2016-02-03 | 福鼎市西坑孔家茶业有限公司 | Compound polygonatum sibiricum wine |
CN106318778A (en) * | 2016-08-31 | 2017-01-11 | 沈飞 | Health-care wine containing polygonatum and brewing method of health-care wine |
CN106722265A (en) * | 2016-10-21 | 2017-05-31 | 南陵县石斛产业协会 | A kind of preparation method of sealwort local flavor sheep lung can |
CN106434219A (en) * | 2016-11-23 | 2017-02-22 | 贺州市杨晋记豆豉有限公司 | Rhizoma polygonati health care wine and brewing method thereof |
CN106947671A (en) * | 2017-03-30 | 2017-07-14 | 杭州华东医药集团贵州中药发展有限公司 | A kind of preparation method of safflower glossy ganoderma health-care wine |
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