CN101756090A - Physical power recovery agent and applications thereof - Google Patents
Physical power recovery agent and applications thereof Download PDFInfo
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- CN101756090A CN101756090A CN200910244938A CN200910244938A CN101756090A CN 101756090 A CN101756090 A CN 101756090A CN 200910244938 A CN200910244938 A CN 200910244938A CN 200910244938 A CN200910244938 A CN 200910244938A CN 101756090 A CN101756090 A CN 101756090A
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- anthocyanidin
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Abstract
The invention discloses a physical power recovery agent and applications thereof. The physical power recovery agent is prepared mainly from the following raw materials in percentage by weight: 45-60 percent of procyanidins, 5-20 percent of anthocyanidins, 5-10 percent of black bean protein or soyabean protein, 5-10 percent of Wolfberry Polysaccharides, 5-10 percent of lentinan, 3-5 percent of Fragrant Solomonseal Rhizome and 3-5 percent of ginsenoside. The invention also discloses the applications of the physical power recovery agent in the preparation of beverages, food or health care products. The raw materials of the physical power recovery agent of the invention are from the natural products which can use both as food and medicine, thus, the physical power recovery agent has high safety. Experiments show that the physical power recovery agent can delay fatigue production, shorten fatigue time, accelerate fatigue elimination, and promote physical power recovery and energy recovery. The physical power recovery agent has the characteristics of good taste, no objectional odor, good curative effect, small dosage, no toxic and side effects for long-term application, convenient application, easy carrying and storage and the like. The physical power recovery agent can make the physical power quickly recovered after large energy consumption, and improve the immunity of the organism.
Description
Technical field
The present invention relates to nutritious supplementary pharmaceutical, particularly relate to a kind of antisecosis agent.
Background technology
Tired (fatigue) is the biochemical change procedure of body complex physical.Owing to motion causes that the organism physiology biochemical change causes the temporarily-depressed phenomenon of body movement ability, is called as exercise induced fatigue
[1]The research of sports medical science circle aspect motion and Radical Metabolism both at home and abroad is rather active in recent years.Discover that motion causes that the active oxygen increase of skeletal muscle free radical and other form is to cause one of major reason of Skeletal muscle injury and fatigue
[2]Additional antioxidant can be prevented this change, improves locomitivity.Glucosidase procyanidins (pracyanidolic oligomers, one of hereinafter to be referred as OPC) the most potent free radical scavenger that is up to now to be found, its Green Tea Extract oxidability is ascorbic 20 times, 50 times of vitamin E, especially its activity in vivo, other antioxidants are incomparable especially
[3-4]
[1] Yu Qian, Li Mingfu, Song Kaiyuan, etc. the integral body of traditional Chinese medicine antibody power fatigue is analyzed mentally and application prospect [J]. Chinese Journal of Sports Medicine, 2001,20 (1): 3-4.
[2] Hu Hongmei is permitted person of outstanding talent's literary composition. the influence [J] of the endogenous radical pair rat heart muscle of motility mitochondrial function. and Chinese Journal of Sports Medicine, 1998,17 (1): 23-25.
[3] Liu association, Li Xiaoning, Bao Liuhang, etc. the antifatigue effect research [J] of grape seed extract OPC. practical preventive medicine, 2004,11 (1): 36-38.
[4] Chen Jidi. nutrition in sport [M]. Beijing: publishing house of Beijing Medical University, 2002.33-37,298-301.
Summary of the invention
The purpose of this invention is to provide a kind of antisecosis agent.
Second purpose of the present invention provides the application of a kind of antisecosis agent in preparation beverage, food or health products.
A kind of antisecosis agent of the present invention gropes to sum up to draw through the inventor in a large number, and each material component consumption all has the effect of better antisecosis in the scope of following weight percentage.
A kind of antisecosis agent is mainly made by following raw material: OPC 45-60% by weight percentage; Anthocyanidin 5-20%; Black soya bean albumen or soybean protein 5-10%; LBP-X 5-10%; Lentinan 5-10%; Rhizoma Polygonati Odorati extract 3-5%; Ginsenoside 3-5%.
Preferably: OPC is mass content 〉=30% of glucosidase procyanidins, and described OPC is grape pip procyanidin, pine tree OPC, apple OPC or hawthorn OPC.
The mass content of anthocyanidin is 〉=7%, and described anthocyanidin is black bean peel anthocyanidin, blueberry anthocyanin, cowberry anthocyanidin, blackcurrant anthocyanidin, indigo fruit anthocyanidin, mulberry fruit anthocyanidin, black rice anthocyanidin, black carrot anthocyanidin, purple sweet potato anthocyanidin.
LBP-X with the matrimony vine be raw material extract obtain, mass content is 〉=80%.
Lentinan with the mushroom be raw material extract obtain, mass content is 〉=80%.
Rhizoma Polygonati Odorati extract is to be that raw material is 4-10 with the volume ratio with the Chinese medicine radix polygonati officinalis: 1 alcohol-water mixed liquor serves as to extract solvent extraction to obtain.
Ginsenoside is that mass content is 〉=10%.
A kind of antisecosis agent; can also comprise vitamin E 0%-5%, vitamin C 0%-5%, probacol 0%-5%, Cobastab 0%-5%, vitamin A 0%-5%, carotenoid 0%-5%, glutathione 0%-5%, selenium 0%-5%, creatine 0%-5%, taurine 0%-5%, amino acid 0%-5%.
Cobastab can be that vitamin B1, vitamin B2, vitamin B6, cobalamin, nicotinic acid, pantothenic acid and folic acid are at least a.
Carotenoid can be that zeaxanthin, lutein, lycopene, astaxanthin or carrotene are at least a.
Amino acid is that lysine, tryptophan, phenylalanine, methionine, threonine, isoleucine, leucine, valine, serine, histidine and arginine are at least a.
The application of antisecosis agent in preparation beverage, food or health products.
The raw material sources of a kind of antisecosis agent of the present invention have high security in the natural products of integration of drinking and medicinal herbs, experimental results show that can delay fatigue generation, shorten the tired time, accelerate tiredly to eliminate, promote the recovery of physical efficiency and energy to recover.The present invention has that mouthfeel is good, free from extraneous odour, curative effect is good, dosage is little, prolonged application has no side effect, use conveniently, be easy to carry and characteristics such as storage.Can make the fast quick-recovery of muscle power after a large amount of physical demands, improve immunity of organisms.
The specific embodiment
The following examples can make those skilled in the art more fully understand the present invention, but do not limit the present invention in any way.
A kind of antisecosis agent of the present invention is a main component with the OPC, and is equipped with anthocyanidin and makes compound preparation in conjunction with black soya bean albumen or soybean protein, matrimony vine glycan, lentinan, Rhizoma Polygonati Odorati extract and ginsenoside again.
The present invention has fine antioxidation, and immunity of organisms can be provided, and replenishes required dietary protein and the dietary fiber of body, and in conjunction with tonic invigorator, regains one's strength of body thereby reach, the nourishing effects of antifatigue, enhancing immunity of organisms.
Used each component or have commercially availablely among the present invention or can reach in accordance with known methods to describe in the document and prepares.
Embodiment 1-embodiment 22 sees Table 1.
Table 1 (being mass percent in the table)
| Embodiment | OPC % | Anthocyanidin % | Black soya bean albumen or soybean protein % | LBP-X % | Lentinan % | Rhizoma Polygonati Odorati extract % | Ginsenoside % | Vitamin E % | Vitamin C % | Probacol % | Cobastab % | Vitamin A % | Carotenoid % | Glutathione % | Selenium % | Creatine % | Taurine % | Amino acid % |
| ??1 | ??50 | ??10 | ??10 | ??10 | ??10 | ??5 | ??5 |
| Embodiment | OPC % | Anthocyanidin % | Black soya bean albumen or soybean protein % | LBP-X % | Lentinan % | Rhizoma Polygonati Odorati extract % | Ginsenoside % | Vitamin E % | Vitamin C % | Probacol % | Cobastab % | Vitamin A % | Carotenoid % | Glutathione % | Selenium % | Creatine % | Taurine % | Amino acid % |
| ??2 | ??60 | ??15 | ??5 | ??6 | ??8 | ??3 | ??3 | |||||||||||
| ??3 | ??45 | ??20 | ??10 | ??10 | ??5 | ??5 | ??5 | |||||||||||
| ??4 | ??60 | ??5 | ??9 | ??9 | ??9 | ??4 | ??4 | |||||||||||
| ??5 | ??55 | ??15 | ??5 | ??5 | ??10 | ??5 | ??5 | |||||||||||
| ??6 | ??45 | ??10 | ??10 | ??10 | ??10 | ??5 | ??5 | ??5 | ||||||||||
| ??7 | ??45 | ??10 | ??10 | ??10 | ??10 | ??5 | ??5 | ??5 | ||||||||||
| ??8 | ??45 | ??10 | ??10 | ??10 | ??10 | ??5 | ??5 | ??5 | ||||||||||
| ??9 | ??45 | ??10 | ??10 | ??10 | ??10 | ??5 | ??5 | ??5 | ||||||||||
| ??10 | ??45 | ??10 | ??10 | ??10 | ??10 | ??5 | ??5 | ??5 | ||||||||||
| ??11 | ??45 | ??10 | ??10 | ??10 | ??10 | ??5 | ??5 | ??5 | ||||||||||
| ??12 | ??45 | ??10 | ??10 | ??10 | ??10 | ??5 | ??5 | ??5 | ||||||||||
| ??13 | ??45 | ??10 | ??10 | ??10 | ??10 | ??5 | ??5 | ??5 | ||||||||||
| ??14 | ??45 | ??10 | ??10 | ??10 | ??10 | ??5 | ??5 | ??5 | ||||||||||
| ??15 | ??45 | ??10 | ??10 | ??10 | ??10 | ??5 | ??5 | ??5 | ||||||||||
| ??16 | ??45 | ??10 | ??10 | ??10 | ??10 | ??5 | ??5 | ??5 | ||||||||||
| ??17 | ??45 | ??10 | ??10 | ??10 | ??10 | ??5 | ??5 | ??1 | ??1 | ??3 | ||||||||
| ??18 | ??45 | ??10 | ??10 | ??10 | ??10 | ??5 | ??5 | ??1 | ??3 | ??1 | ||||||||
| ??19 | ??45 | ??10 | ??10 | ??10 | ??10 | ??5 | ??5 | ??1 | ??2 | ??1 | ??1 | |||||||
| ??20 | ??45 | ??10 | ??10 | ??10 | ??10 | ??5 | ??5 | ??1 | ??1 | ??1 | ??1 | ??1 | ||||||
| ??21 | ??45 | ??10 | ??10 | ??10 | ??10 | ??5 | ??5 | ??1 | ??1 | ??1 | ??1 | ??1 | ||||||
| ??22 | ??45 | ??10 | ??10 | ??10 | ??10 | ??5 | ??5 | ??1 | ??1 | ??1 | ??1 | ??1 |
The albumen of embodiment 1-3,7-12, embodiment 17, embodiment 19 and embodiment 21 is to use black soya bean albumen in the table 1.All the other are soybean protein.
The Cobastab of embodiment 9 is that mass ratio is 1: 1 vitamin B1 and a vitamin B2.
The carotenoid of embodiment 11 is that mass ratio is 1: 1 zeaxanthin and a lutein.
The amino acid of embodiment 16 is that mass ratio is 1: 1: 1: 1: 1 lysine, tryptophan, phenylalanine, methionine, threonine.
The Cobastab of embodiment 18 is that mass ratio is 1: 1: 1 vitamin B6, cobalamin, a nicotinic acid.
The Cobastab of embodiment 19 is a pantothenic acid.Amino acid is isoleucine.
The Cobastab of embodiment 20 is a folic acid.Carotenoid is that mass ratio is 1: 1 lycopene, an astaxanthin.Amino acid is leucine.
The Cobastab of embodiment 21 is a vitamin B1.Carotenoid is carrotene.Amino acid is valine.
The Cobastab of embodiment 22 is a vitamin B2.Amino acid is that mass ratio is 1: 1 histidine and an arginine
Embodiment 23 The pharmacological results
The prescriptive procedure that this experimental technique is measured according to swimming with a load attached to the body test in " alleviating physical fatigue detection method " in " the health food function assessment assessment process and the method for inspection " of health ministry issue, serum urea mensuration, hepatic glycogen mensuration and blood lactic acid is carried out.
1. dosage and grouping:
The used mouse of swimming test and every biochemical test (liver glycogen, blood lactic acid and hemoglobin) all is divided into 4 groups by body weight, 10 every group at random.If basic, normal, high three dosage groups (dosage is respectively 25,50,100mg/Kg, the RD that is equivalent to be grown up 5,10,20 times) and a solvent control group are tried thing and are mixed with the desired concn per os and irritate stomach, continuously 30d.The solvent control group gives distilled water, and the mouse stomach amount is 20ml/b.wt.All animals all gives the mouse full-valence pellet feed and freely eats.
2. swimming time is measured:
The last per os is irritated after stomach tried thing 30min, and the load sheet lead of 5% body weight of mouse root of the tail portion is put mouse in the swimming case, and the depth of water is greater than 30cm, water temperature (25 ± 0.5) ℃, the record mouse from the swimming beginning to the dead time, as mouse swimming time (min).
3. the mensuration of anti-fatigue test biochemical indicator
(1) blood lactic acid is measured: after art time was tried thing 30min, 2% (body weight) of bearing a heavy burden swum in 30 ± 1 ℃ of water and stopped behind the 10min.Respectively before swimming, swimming back 0,15,60min be with the blood sampling of glass capillary eyeball angular vein.Measure the content of each sample full blood lactic according to the requirement of full blood lactic detection kit.
(2) hepatic glycogen content is measured: after last is tried thing 30min, be the 60min that swims in 30 ± 1 ℃ of water, put to death immediately, dissect and get liver in temperature, and the physiological saline rinsing, filter paper blots, and weighs, and carries out liver glycogen then and measures.Concrete operations are pressed liver glycogen and are measured the kit specification.
(3) serum urea is measured (DAM method): after last is tried thing 30min, be not swimming with a load attached to the body 90min in 30 ℃ ± 1 ℃ the water in temperature, behind the rest 60min, pluck eyeball blood sampling 0.5ml (not adding anti-coagulants).Put 4 ℃ of about 3h of refrigerator, treat blood clotting after, the centrifugal 15min of 2000prn/min gets serum and measures kit with serum urea and measure.
Data Processing in Experiment: data represent with x ± s, with the analysis that takes statistics of SPSS11.0 software, relatively adopt t check in groups.There is statistical significance P＜0.05.
4. result
(1) by table 2 as seen swimming with a load attached to the body is tested, and each dosage group mouse swimming time all is higher than the value of control group, and has dosage one reaction relation, the swimming time of middle and high dosage group mouse to compare utmost point significant difference (P＜0.01) with control group.Illustrate that powder of the present invention can obviously prolong the mouse swimming with a load attached to the body time when high dose (100mg/kg), middle dosage (50mg/kg).
Table 2 a kind of antisecosis agent of the present invention is to the effect of mouse swimming with a load attached to the body time (x ± s)
(2) to the influence of blood lactic acid content behind the mouse movement:
By before the test mouse movement, the blood lactic acid content of motion back 0,15 and 60min, find that antisecosis agent high dose group can obviously slow down the increase of mouse blood lactic acid after the strenuous exercise, and the content before trending towards swimming, each dosage group of finding the antisecosis agent of swimming when measuring again in back 15 minutes all has the effect that mouse blood lactic acid reduces after the accelerated motion, do in order to high, middle dosage group is particularly evident.
The agent of table 3 antisecosis is to the influence (mean ± SD n=10) of mouse full blood lactic
(3) to the influence of Mouse Liver glycogen, serum urea content: hepatic glycogen content all is higher than control group behind each dosage group mouse movement, has respectively significantly and utmost point significant difference (P＜0.05, P＜0.01), and dosage one reaction relation is arranged.Each dosage group mice serum content of urea all is higher than the content of control group, especially the serum urea content of high dose group and control group has significant difference (P＜0.01), illustrates that the antisecosis agent of high dose has the effect of the serum urea content that reduces motion back mouse.
The agent of table 4 antisecosis is to the Mouse Liver glycogen, the effect of hemoglobin and blood lactic acid
* and blank group contrast, P＜0.01; * compare P＜0.05 with the blank group
A kind of nutritional supplement, the nutritious supplementary pharmaceutical that regains one's strength especially fast.So-called antisecosis agent just is meant and can improves and recover because physical demands and the fatigue that motion produces later.
The antisecosis agent can method routinely prepare beverage, food or health products.
Claims (10)
1. antisecosis agent is characterized in that mainly being made by following raw material by weight percentage: OPC 45-60%; Anthocyanidin 5-20%; Black soya bean albumen or soybean protein 5-10%; LBP-X 5-10%; Lentinan 5-10%; Rhizoma Polygonati Odorati extract 3-5%; Ginsenoside 3-5%.
2. a kind of antisecosis agent according to claim 1, it is characterized in that described OPC is mass content 〉=30% of glucosidase procyanidins, described OPC is grape pip procyanidin, pine tree OPC, apple OPC or hawthorn OPC.
3. a kind of antisecosis agent according to claim 1, the mass content that it is characterized in that described anthocyanidin is 〉=7%, and described anthocyanidin is black bean peel anthocyanidin, blueberry anthocyanin, cowberry anthocyanidin, blackcurrant anthocyanidin, indigo fruit anthocyanidin, mulberry fruit anthocyanidin, black rice anthocyanidin, black carrot anthocyanidin, purple sweet potato anthocyanidin.
4. a kind of antisecosis agent according to claim 1, it is characterized in that described LBP-X with the matrimony vine be raw material extract obtain, mass content is 〉=80%.
5. a kind of antisecosis agent according to claim 1, it is characterized in that described lentinan with the mushroom be raw material extract obtain, mass content is 〉=80%.
6. a kind of antisecosis agent according to claim 1 is characterized in that described Rhizoma Polygonati Odorati extract is is that raw material is 4-10 with the volume ratio with the Chinese medicine radix polygonati officinalis: 1 alcohol-water mixed liquor serves as to extract solvent extraction to obtain.
7. a kind of antisecosis agent according to claim 1 is characterized in that described ginsenoside is that mass content is 〉=10%.
8. a kind of antisecosis agent according to claim 1; it is characterized in that also comprising vitamin E 0%-5%, vitamin C 0%-5%, probacol 0%-5%, Cobastab 0%-5%, vitamin A 0%-5%, carotenoid 0%-5%, glutathione 0%-5%, selenium 0%-5%, creatine 0%-5%, taurine 0%-5%, amino acid 0%-5%.
9. a kind of antisecosis agent according to claim 1 is characterized in that described amino acid is that lysine, tryptophan, phenylalanine, methionine, threonine, isoleucine, leucine, valine, serine, histidine and arginine are at least a.
10. the application of the antisecosis agent of one of claim 1-9 in preparation beverage, food or health products.
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