CN102370758A - Antitumor traditional Chinese medicine - Google Patents
Antitumor traditional Chinese medicine Download PDFInfo
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- CN102370758A CN102370758A CN2010102507633A CN201010250763A CN102370758A CN 102370758 A CN102370758 A CN 102370758A CN 2010102507633 A CN2010102507633 A CN 2010102507633A CN 201010250763 A CN201010250763 A CN 201010250763A CN 102370758 A CN102370758 A CN 102370758A
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Abstract
The invention relates to an antitumor traditional Chinese medicine. The antitumor traditional Chinese medicine has the advantages of obvious tumor inhibition effects, small toxic and side effects, clinical coordination with radiotherapy and chemotherapy, and good effects of treating lung cancer and digestive tract cancer.
Description
The present invention relates to a kind of Chinese medicine, particularly relate to a kind of anti-tumor compound Chinese medicine.
Malignant tumor is the disease of serious harm human health; Existing antitumor drug is cytotoxic drug mostly; Such medicine also has infringement to the human normal cell in killing tumor cell, serious destruction immunity of organism organ; Make tumor patient quality of life low, increase in life span descends.China's Chinese medicine has long clinical application basis, press down aspects such as tumor, immunostimulant in treating the poisonous disease with poisonous drugs, immunity and developed many PTSs, but most tumor killing effect is not good.
The purpose of this invention is to provide a kind of effective tumor suppression medicine, it can remedy the above-mentioned deficiency of existing medicine.
A kind of antineoplastic Chinese medicine is characterized in that containing the Radix Astragali, Polyporus, the Rhizoma Atractylodis Macrocephalae, Sargassum, the Radix Linderae, Endothelium corneum, Herba Hedyotidis Diffusae, and the ratio of their parts by weight is: 50-100: 50-100: 50-100: 50-100: 50100: 20-50: 20-50.
A kind of antitumor preparation method of Chinese medicine; It is characterized in that each Chinese medicine component is pulverized is coarse powder, extracts with 60 ℃ of-80 ℃ of water-baths of diluted acid water of 8-12 times of weight, filters; 60 ℃ of-80 ℃ of water-baths of the diluted alkaline water of 8-12 times of weight of medicinal residues reuse are extracted; Merge the soda acid extracting solution, concentrating under reduced pressure adds to compose and expects to process granule.
Process for preparing medicine of the present invention is simple to operate, the cycle is short, active constituent content is high, and cost of manufacture is low; This medicine can significantly improve body's immunity, obviously improves the life quality of tumour patient.
Through embodiment the present invention is described below.
Take by weighing Radix Astragali 75g, Polyporus 75g, Rhizoma Atractylodis Macrocephalae 75g, Sargassum 75g, Radix Linderae 75g, Endothelium corneum 35g, Herba Hedyotidis Diffusae 35g; It is coarse powder (20-80 order) that each Chinese medicine component is pulverized, and extracts twice with 80 ℃ of water-baths of diluted acid water (pH2-4) of 10 times of weight, filters; 80 ℃ of water-baths of the diluted alkaline water (pH7.5-9.5) of 8-12 times of weight of medicinal residues reuse are extracted twice; Merge the soda acid extracting solution, concentrating under reduced pressure, adding dextrin, Icing Sugar excipient are processed granule.The preparation of making for carrying mark, adopts high performance liquid chromatogram and phenolsulfuric acid method to carry out quality control standard with the content of active ingredient astragaloside and total polysaccharides.
Chinese medicine of the present invention is formed by the principle of Chinese traditional treatment tumor.Radix Astragali tonifying Qi and lifting yang wherein has tonification preferably to promote for the deficiency of vital energy of spleen lung and does to have, stop gathering the merit that inducing diuresis to remove edema can be arranged because of insufficiency of the spleen fortune water is wet; But the Rhizoma Atractylodis Macrocephalae is air making-up and spleen enlivening, dampness, diuretic also, square for this reason monarch drug, and Sargassum is salty-cold, antiinflammatory softening the hard mass, broken eliminating stagnation gas; Polyporus diuresis, eliminating dampness by diuresis, that expectorant is given birth to is passive, for this reason the ministerial drug of side.The Herba Hedyotidis Diffusae heat-clearing and toxic substances removing is invigorated blood circulation and is gone up pain, can separate expectorant blood coagulation stasis of blood poison and accumulate, and the merit of inducing diuresis to remove edema is arranged, for this reason the adjuvant drug of side.The Endothelium corneum activating the spleen helps digestion, in case stagnation of dampness due to deficiency of the spleen, and failing of the spleen to transport and cause dyspepsia; The hot Wen Xiang of the Radix Linderae scurries, on walk the spleen lung, the reason breast abdomen stagnation of QI, promoting the circulation of QI to relieve pain are assigned kidney and bladder, warming kidney for dispelling cold, sensible yang-energy so that part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels water channel is unobstructed, has both helped absorption, the running of medicine, anti-again all sweet stagnant colds of medicine are cold, for this reason the messenger drug of side.
In sum, the Radix Astragali is mended the gas of strengthening spleen and lung, and invigorating spleen to remove dampness, the Rhizoma Atractylodis Macrocephalae help its power; The Sargassum eliminating phlegm and softening indurated mass, broken eliminating stagnation gas, Polyporus is strengthened its usefulness; The Herba Hedyotidis Diffusae heat-clearing and toxic substances removing, promoting blood circulation and stopping pain; Endothelium corneum, the Radix Linderae are transferred sharp taste, and sensible yang-energy had both helped the absorptions running of medicine, and anti-again all sweet stagnant colds of medicine are cold, and the group medicine of full side is auxilliary mutually to be usefulness, focus on QI invigorating, spleen invigorating, reduce phlegm, eliminating stagnation.
Medicine of the present invention has QI invigorating, spleen invigorating, reduces phlegm, the eliminating stagnation effect, by the pharmacodynamics requirement of the anticancer centralizing function of Chinese medicine, with mice S
180Solid tumor, mice Emhorn ascitic type tumor are that model has been observed inhibition and the life prolongation effect of said preparation to tumor growth; And observe it to tumor-bearing mice spleen antibody-producting cell, the influence of Turnover of Mouse Peritoneal Macrophages phagocytic function and tumor-bearing mice thymus, spleen weight.The result shows: said preparation can significantly suppress mice S
180The solid tumor growth prolongs ascitic type mice with tumor life span; And obviously increase the weight of tumor-bearing mice immune organ, and improve the Turnover of Mouse Peritoneal Macrophages phagocytic function, promote the generation of tumor-bearing mice spleen antibody-producting cell simultaneously.
Clinical drug of the present invention is according to different sick sensitivity and different situations combined with radiotherapy or chemotherapy of planting radiotherapy, chemotherapy, and one month is a course of treatment.Put, still can continue to take behind the end of chemotherapy, generally take 2-6 the course of treatment.Treat 20 examples altogether, pulmonary carcinoma 5 examples wherein, human primary gastrointestinal cancers 15 examples; Effective percentage is pressed the CR+PR statistics, and life quality is pressed Ka Shi scoring statistics, and curative effect and life quality analysis all are higher than the radiation alone and the chemotherapy group of general bibliographical information; This side of experiment proof has tumour inhibiting rate preferably, does not have obvious toxic and side effects.
Claims (2)
1. an antineoplastic Chinese medicine is characterized in that containing the Radix Astragali, Polyporus, the Rhizoma Atractylodis Macrocephalae, Sargassum, the Radix Linderae, Endothelium corneum, Herba Hedyotidis Diffusae, and the ratio of their parts by weight is: 50-100: 50-100: 50-100: 50-100: 50-100: 20-50: 20-50.
2. antitumor preparation method of Chinese medicine; It is characterized in that each Chinese medicine component is pulverized is coarse powder, extracts with 60 ℃ of-80 ℃ of water-baths of diluted acid water of 8-12 times of weight, filters; 60 ℃ of-80 ℃ of water-baths of the diluted alkaline water of 8-12 times of weight of medicinal residues reuse are extracted; Merge the soda acid extracting solution, concentrating under reduced pressure adds to compose and expects to process granule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010102507633A CN102370758A (en) | 2010-08-11 | 2010-08-11 | Antitumor traditional Chinese medicine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010102507633A CN102370758A (en) | 2010-08-11 | 2010-08-11 | Antitumor traditional Chinese medicine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102370758A true CN102370758A (en) | 2012-03-14 |
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ID=45790342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010102507633A Pending CN102370758A (en) | 2010-08-11 | 2010-08-11 | Antitumor traditional Chinese medicine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102370758A (en) |
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2010
- 2010-08-11 CN CN2010102507633A patent/CN102370758A/en active Pending
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| Date | Code | Title | Description |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20120314 |