CN115192662A

CN115192662A - Traditional Chinese medicine composition and medicine for treating tumors

Info

Publication number: CN115192662A
Application number: CN202210297575.9A
Authority: CN
Inventors: 骆效黎; 侯诚; 屈会青; 陈晨
Original assignee: Individual
Current assignee: Individual
Priority date: 2022-03-25
Filing date: 2022-03-25
Publication date: 2022-10-18

Abstract

The invention provides a traditional Chinese medicine composition for treating tumors, which is prepared from the following raw material medicines in parts by weight: ginseng, longan, inonotus obliquus, lucid ganoderma, astragalus, tuckahoe, fried white paeony root, yam and at least two of oldenlandia diffusa, glaucescent fissistigma root and barbed skullcap; grinding the raw materials into powder, mixing with Mel to obtain paste, and making into pill, tablet, powder or capsule; the main medicine is the traditional Chinese medicine composition, and the guiding drug comprises millet, noni, chinese yam, ginger, ferment bacteria and adult live scorpions. The medicine of the invention is used for treating various tumors, has definite curative effect, is convenient, cheap, safe and reliable, and is a good medicine for treating tumors.

Description

Traditional Chinese medicine composition and medicine for treating tumors

Technical Field

The invention relates to the technical field of medicaments for treating tumors, in particular to a traditional Chinese medicine composition for treating tumors and a medicament.

Background

The human body has the capacity of self-protection and self-healing. It also has self-body resistance to tumor. When the self-protection function of the human body is enough to restrain cancer toxicity, the human body is normal; when the self-protection ability of the human body is insufficient, the occurrence of tumor is shown. Malignant tumors are serious diseases that seriously harm human life and health, and are the second cause of death due to high lethality. According to the data of SEER (epidemic organization, epidemic organization and Results program), tumors are lumps or special lesions formed by abnormal hyperplasia of local tissue cells of a human body and can be divided into benign tumors and malignant tumors; the tumor diseases are a big problem which is always puzzled and unsolved in the medical field for years, millions of people die due to the tumor diseases every year, the number of people die due to the diseases is the top number of the people, and the tumor diseases seriously affect the life health of the people and the development of national economy.

At present, western medicine generally adopts three methods of chemotherapy, radiotherapy and operation in the aspect of treating tumors, wherein the operation treatment is a means of local treatment, the tumor is easy to recur after the operation, the operation is not easy to radically treat the tumor, the side effects of the radiotherapy and the chemotherapy are great, serious iatrogenic diseases and sequelae can be caused, even organ failure can be caused, and the difference and the harm are mainly as follows:

1. chemotherapy is one of methods for treating tumors systemically, and has side effects of mainly destroying the hematopoietic system of the whole body and reducing the immune function, and also causing damage to organs such as heart, digestive function, nerves and the like, so that the side effects of chemotherapy are great, and even the currently prevailing targeted drug therapy has no curative effect to the full extent.

2. Radiotherapy is a method for locally treating tumors, and can cause severe damage, even irreversible damage, to local normal tissues, so that the organs lose functions, for example, liver radiotherapy can cause liver cirrhosis and liver atrophy, lung radiotherapy can cause pulmonary fibrosis, thereby causing pulmonary dysfunction, most commonly, a series of concurrent diseases such as difficult sputum discharge and respiratory function loss cause dyspnea, sputum accumulation in the lung, pulmonary infection and the like. If the radiation treatment is applied to the heart, the heart is damaged, causing cardiac dysfunction, and if the radiation treatment is applied to hollow organs such as the stomach and the intestine, the organs lose functions.

In summary, chemotherapy and radiotherapy have significant side effects and require strict and rational choice of the indication. Chemotherapy and radiation therapy are therefore less suitable for the treatment of tumors, in order to avoid unnecessary medical consequences.

At present, more traditional Chinese medicines are adopted for treating tumors, such as: 1. the invention discloses a patent with the application number of '200410018190.6' and the name of the invention is 'a traditional Chinese medicine preparation for treating tumors', and the medicine disclosed by the invention has the effects of eliminating phlegm and dampness, eliminating mass and blood stasis, promoting qi circulation and eliminating phlegm, warming middle-jiao and promoting appetite, dredging collaterals and activating stagnancy, promoting blood circulation and removing blood stasis, relieving swelling and resolving masses, and clearing heat and removing toxicity. But the effect is not obvious enough in the treatment of the tumor, and the traditional Chinese medicine has side effects, is easy to relapse after long-term use and has unsatisfactory radical treatment effect. 2. The patent with the application number of '200410058013.0' and the invention name of 'an anti-tumor pharmaceutical composition' discloses the pharmaceutical composition which mainly comprises raw material medicines of pangolin, plant soot, common burreed rhizome, zedoary, almond, dark plum, chicken's gizzard-membrane, dragon's blood, subprostrate sophora, borax, akebia stem, rhubarb, immature bitter orange, peach seed, fluorescent rice, black bean, frankincense, myrrh, mung bean, catechu, cuttle bone, agilawood, rhizoma corydalis, costustoot, cinnabar, pumice, white mustard seed, aspongopus and the like. The medicine has the effects of clearing heat and detoxicating, softening and resolving hard mass and resisting tumor, but has not obvious effect on treating lymphadenitis, scrofula, lymphoma, nasopharyngeal carcinoma, rectal cancer and esophageal cancer, and has side effect. 3. The invention discloses an invention patent with the application number of '200410035579.1' and the name of 'Xiaoliusan', wherein the disclosed medicament mainly comprises walleye, stiff silkworm, silkworm cocoon, vermilion, chinese date, spider, angelica, bunge corydalis herb, myrrh and the like. The medicine can be used for treating hyperplasia of mammary glands, mastitis, breast tumor, toxic sore, thyroid tumor, lymph node tumor, etc., but the treatment effect is not obvious, and recurrence symptom is easy to occur.

In order to solve the problem of tumor, people are continuously exploring and researching to find out the cause of the tumor, summarize the scheme for treating and preventing the tumor, develop the effective medicament for treating the tumor, obtain a certain treatment effect clinically, and make great contribution to the prevention and treatment of the tumor for human beings. Nevertheless, the therapeutic effect of the existing Chinese medicinal preparations is still unsatisfactory.

Disclosure of Invention

In order to solve the problems, the invention provides a traditional Chinese medicine composition and a medicine for treating tumors. The medicine of the present invention is used in treating various tumors and has obvious treating effect, less side effect and low cost.

The invention adopts the following technical scheme:

a traditional Chinese medicine composition for treating tumors is prepared from the following raw material medicines in parts by weight: ginseng, longan, inonotus obliquus, lucid ganoderma, astragalus, tuckahoe, fried white paeony root, yam and at least two of oldenlandia diffusa, glaucescent fissistigma root and barbed skullcap herb. The invention starts from human tissue embryology origins and tumor pathogenesis, and mainly takes oldenlandia diffusa as tumors from embryonic period endoderm, glaucescent fissistigma glaucescens as tumors from embryonic period mesoderm and barbed skullcap herb as tumors from embryonic period ectoderm.

Further, the traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 90-110 parts of ginseng, 90-110 parts of longan, 90-110 parts of inonotus obliquus, 90-110 parts of lucid ganoderma, 90-110 parts of astragalus membranaceus, 90-110 parts of poria cocos, 50-70 parts of fried white paeony root, 90-110 parts of Chinese yam, and at least two of 20-70 parts of oldenlandia diffusa, 20-70 parts of glaucescent fissistigma root and 20-70 parts of sculellaria barbata.

A traditional Chinese medicine composition for treating tumors is prepared from the following raw material medicines in parts by weight: 100 parts of ginseng, 100 parts of longan, 100 parts of inonotus obliquus, 100 parts of lucid ganoderma, 100 parts of astragalus membranaceus, 100 parts of poria cocos, 60 parts of oldenlandia diffusa, 60 parts of glaucescent fissistigma root, 60 parts of fried white paeony root and 100 parts of Chinese yam. The Chinese medicinal composition can effectively treat tumors derived from embryonic endoderm, such as lung tumor, kidney tumor and cardiovascular system tumor.

A traditional Chinese medicine composition for treating tumors is prepared from the following raw material medicines in parts by weight: 100 parts of ginseng, 100 parts of longan, 100 parts of inonotus obliquus, 100 parts of lucid ganoderma, 100 parts of astragalus membranaceus, 100 parts of poria cocos, 60 parts of sculellaria barbata, 60 parts of glaucescent fissistigma root, 60 parts of fried white paeony root and 100 parts of Chinese yam. The Chinese medicinal composition can effectively treat tumors derived from embryonic mesoderm, such as blood tumor, bone tumor and digestive system tumor.

A traditional Chinese medicine composition for treating tumors is prepared from the following raw material medicines in parts by weight: 100 parts of ginseng, 100 parts of longan, 100 parts of inonotus obliquus, 100 parts of lucid ganoderma, 100 parts of astragalus membranaceus, 100 parts of poria cocos, 60 parts of oldenlandia diffusa, 60 parts of sculellaria barbata, 60 parts of fried white paeony root and 100 parts of Chinese yam. The Chinese medicinal composition can effectively treat tumors derived from embryonic ectoderm, such as brain tumor, nervous system tumor and skin tumor.

Furthermore, any of the above traditional Chinese medicine compositions for treating tumors can be prepared into clinically acceptable pharmaceutical preparations according to the conventional traditional Chinese medicine preparation method.

Further, the pharmaceutical preparation is a pill, a tablet, a powder or a capsule.

Further, the preparation method of the pharmaceutical preparation comprises the following steps: grinding the raw material medicines into powder with the granularity of 100-200 meshes, mixing the powder with honey into paste, and preparing the paste into pills, tablets, powder or capsules.

The invention also provides a medicament for treating tumors, which comprises a main medicament and a guiding medicament, wherein the main medicament is any one of the traditional Chinese medicine compositions for treating tumors, and the guiding medicament comprises millet, noni, chinese yam, ginger, ferment bacteria (such as saccharomycetes) and adult live scorpions.

Further, the preparation method of the guiding drug comprises the following steps:

step A: cleaning semen Setariae, morinda Citrifolia, rhizoma Dioscoreae, and rhizoma Zingiberis recens, air drying, placing into a clean jar, adding Mel (or not), adding purified water to cover the raw materials, adding ferment bacteria, sealing the jar, and standing at room temperature for at least 3 months to obtain ferment liquid as a dispensing guide;

and B, step B: soaking live adult scorpion in white wine for more than 1 minute, washing with purified water, adding the enzyme solution obtained in the step A, crushing, and mixing the crushed solution to obtain the guiding drug 1 time a day.

And further, honey and fresh orange juice are added during crushing in the step B.

step A: 40-60 parts of millet, 5-20 parts of noni, 5-20 parts of Chinese yam and 5-20 parts of ginger are cleaned, aired and placed into a clean jar, 5 parts of honey (or no honey) is added, purified water is added to cover the raw materials, 10-20 parts of ferment bacteria are added, the mouth of the sealed jar is placed at normal temperature for at least 3 months, and ferment liquid is obtained and is used as a dispensing guide for standby; preferably, the feed comprises 50 parts of millet, 10 parts of noni, 10 parts of Chinese yam, 10 parts of ginger, 5 parts of honey and 15 parts of ferment bacteria;

and B: soaking 10 live adult scorpions in 58-degree white spirit for more than 1 minute (preferably 1-3 minutes), washing with purified water, adding 30ml of the enzyme solution obtained in the step A, 30ml of honey and 30ml of fresh orange juice, crushing, and mixing the crushed mixture to obtain the guiding drug 1 time per day. The addition amount of honey and fresh orange juice is not limited, and can be more or less or not.

The medicine taking method for treating the tumor comprises the following steps:

the pill prepared by the traditional Chinese medicine composition is 15g per pill and is taken 1 time a day; the guiding drugs are administered 1 time per day (i.e. 10 live adult scorpions per day).

The pharmacological action of various raw materials of the invention is as follows: live scorpions: the guiding drug of the invention is also the leading drug of the product. The fresh Scorpio contains scorpion venom (Butotoxin), and chemical components such as trimethylamine, betaine, taurine, soft and stearic acid, cholesterol, lecithin and amine salt. In order to further improve the anti-tumor effect and reduce the toxic and side effects of scorpion, people are trying to extract the anti-cancer effective components from scorpion by using different biochemical separation methods. Zhang fu, together with Scorpio extract obtained by ethanol heating and refluxing, can be injected into subcutaneous tumor-bearing mice to significantly reduce DNA in two tumor tissues of reticulocytic Sarcoma (SR) S and breast cancer (MA-737), and significantly inhibit tumor growth. Further research shows that the scorpion crude extract (obtained by extracting scorpion powder with ethanol and then decompressing and concentrating) can lead the human cervical cancer cells (Hlea cells) cultured in vitro to be completely killed and detached from the wall, and presents obvious quantity-effect relationship. The scorpion crude extract not only has obvious inhibition effect on the tumor growth of lung adenocarcinoma (LA-795) tumor-bearing mice, but also can prevent thymus gland atrophy, recover and enhance the immunologic function of thymus gland, so that the organism still has higher inhibition rate on the tumor growth after drug withdrawal. In addition, the alcohol preparation of scorpion can obviously inhibit the respiration of human liver cancer cells in vitro and has obvious inhibition effect on colon cancer and the growth of human liver cancer cells. 1, the effective components of the scorpion venom have less adverse reaction compared with other tumor chemotherapy medicaments; 2. scorpion venom does not inhibit the immune function of tumor host, and even enhances the immune function of organism; 3. scorpion venom has obvious inhibiting effect on human rectum adenocarcinoma cell, and the adenocarcinoma cell is insensitive to chemotherapy and radiotherapy. The current research shows that the scorpion venom has certain inhibition and killing effects on some tumors and has remarkable effect on treating some tumors of human beings, so that the development of the scorpion venom anti-tumor research has very wide prospect. According to the reports of Wangxian on science and technology daily news/2010/7 months/1 day/011 th edition pharmaceutical industry vertical and horizontal columns, scientific researchers of Beijing Henzotang biological science and technology Limited company develop and research in 1992, and discover and successfully provide a small molecular structure, namely protease with high activity, which plays an important determining role in the growth and development process of human thymus from the thymus of east Asia Buthus martensii Karsch with strongest immunity and highest medicinal value. Through purification treatment by a special process, the live scorpion protease with the purity of 100 percent contains various cell factors capable of activating the thymus of a human body, so that immune cells and a nervous system can be directly activated, special factors capable of directly killing cancer cells can be directly killed, and the activity of the live scorpion protease reaches 2500 times of that of the thymus protease of the human body. Experiments prove that: once entering human body, the super active proteinase can develop strong action to human thymus again to regenerate immune system, gradually restore the function of immune system to 20 years old optimum state and make the function of immune system undergo the process of leap transformation. The immunity, killing and repairing capability of the human body is improved to a new level from the root, and the purposes of killing cancer cells, controlling tumor development, shrinking or stripping tumor tissues and preventing relapse and metastasis are achieved, so that the purposes of prolonging life time, improving life quality and continuing the survival of patients are achieved. The advent of "live scorpion thymic proteinase", a scientific research result, is known to make a prominent contribution to promoting the development of biotechnology in China and to be certified by the enzyme expert committee of Chinese academy of sciences. It is worth pointing out that half of the lethal dose (LD 50) of scorpion venom in the gavage of Kunming mice is hundreds of times of that of LD50 injected in the abdominal cavity, and the effective dose of the gavage for resisting tumor is equivalent to the effective dose of the LD50 injected in the abdominal cavity, so that the scorpion venom has higher oral safety factor when being used as an anti-tumor medicament.

Scorpions are traditional Chinese medicinal materials with high medicinal value, have the effects of dredging collaterals, relieving pain, eliminating stagnation, counteracting toxic substances, calming endogenous wind, suppressing spasm, resisting cancer, enhancing immunity, promoting cell regeneration and the like, and are clinically used for treating diseases caused by headache, arthralgia, convulsion, spasm, stroke, toothache, deafness, snake and insect bite, intestinal carbuncle and the like. Grinding Scorpio, radix Curcumae, and Alumen into powder, and administering once a day for treating epilepsia; the scorpion and the giant typhonium rhizome and the stiff silkworm can treat the half-body stiffness caused by the stroke, the scorpion can also promote the metabolism, help the body to dispel the wind evil in the body and dredge the channels and collaterals, besides the medicinal value, the scorpion and the stiff silkworm are also good high-grade delicious food, are rich in nutrition, can prevent and treat diseases when eaten, can enhance the immunity of the body and have the anti-aging function, are popular with people, and clinical experiments prove that the scorpion extract has obvious sterilization effect on cysticercus cellulosae. The scorpion venom has the functions of dispelling wind, detoxicating, relieving pain and dredging meridian, and has certain curative effect on esophagus cancer, liver cancer, colon cancer and other cancers.

Ginseng: ginseng has effects of invigorating primordial qi, restoring pulse, relieving depletion, invigorating spleen, benefiting lung, promoting fluid production, nourishing blood, tranquilizing mind, and improving intelligence. The ginseng has the functions of inhibiting cancer cell metastasis, enhancing the immunity of the organism, enhancing the hematopoietic function and quickly recovering the physique, also has the functions of exciting central nerves, resisting fatigue, improving memory and promoting the synthesis of DNA and RNA, can quickly relieve fatigue, delay senility and inhibit platelet aggregation, has stronger functions of reducing blood fat and resisting arteriosclerosis, also has the functions of resisting shock, expanding blood vessels, improving myocardial blood oxygen and protecting cardiac muscle and quickly improves myocardial ischemia.

Longan: longan is commonly called longan pulp. The sweet nature and taste are mild and warm, have no toxicity, enter heart, spleen and stomach channels, and have the functions of mainly tonifying heart and spleen, replenishing qi and blood, strengthening spleen and stomach and nourishing muscle. Anxiety impairs the spleen, dizziness, insomnia, palpitation, weakness after illness or childbirth, and blood loss due to spleen deficiency. Has effects in invigorating heart and spleen, invigorating qi and blood, and strengthening spleen and stomach. The Chinese patent medicine spleen-invigorating pill is usually combined with other medicines to form the Chinese patent medicine spleen-invigorating pill, is mainly used for treating dizziness, insomnia, palpitation and the like caused by spleen and stomach weakness due to excessive thinking, also can cause body weakness after illness or postpartum, and blood loss caused by spleen deficiency, and can be prepared from longan pulp, namely longan. It can also be used for treating metrorrhagia and metrostaxis caused by spleen qi deficiency and heat, such as menorrhagia and dysfunctional uterine bleeding. It can also be used for enriching blood, so that longan aril has the functions of enriching blood and raising immunity of human body. Besides being used for traditional Chinese medicines, the Chinese medicinal tea can also be used for making tea, or can be applied to food.

And (3) Inonotus obliquus: the inonotus obliquus is a medicinal fungus, has mild nature and sweet taste, and has good health-care effect. Contains polysaccharide and triterpenes, and has antiviral, immunity improving, and common cold preventing effects; can regulate spleen and stomach, protect intestinal health, and treat various digestive system diseases; can clean blood vessel, reduce blood pressure and blood sugar, and prevent cardiovascular and cerebrovascular diseases and diabetes; can eliminate free radicals in vivo, protect skin health, care skin, and delay aging. The Inonotus obliquus also contains SOD activity, and can be used for preventing various tumors.

Lucid ganoderma: the ganoderma lucidum spore powder has the following main effects:

1. the anticancer effect is as follows: the ganoderma lucidum spore powder has obvious inhibition effect on various tumor cells. Used in combination with radiotherapy and chemotherapy of malignant tumor patients, has effects in improving tolerance of patients, relieving side effects, improving hematopoietic function of bone marrow, increasing leukocyte metastasis and recurrence, enhancing immunity, and promoting rehabilitation. After being taken by patients with late-stage cancer, the health and the anti-cancer ability of the patients can be enhanced, the occurrence and the development of complications can be relieved, the survival period can be prolonged, and the life quality can be improved.

2. Treating cardiovascular diseases: the Ganoderma spore powder has effects of regulating blood pressure, dilating coronary artery blood flow, improving microcirculation, increasing myocardial oxygen supply, purifying blood, reducing cholesterol and neutral fat content in blood, preventing and dissolving thrombus in blood vessel, promoting blood circulation, protecting acute myocardial ischemia, and reducing formation of atherosclerotic plaque. Has better prevention and auxiliary treatment effects on coronary heart disease, angina, arteriosclerosis, hypertension, hyperlipidemia and other diseases.

3. Treating digestive system diseases: the Ganoderma spore powder has effects of protecting liver, removing toxic substances, promoting metabolism of liver to medicine and toxic substances, improving liver regeneration capability, and effectively improving liver function. Can improve pancreas blood circulation, improve pancreas physiological function, and reduce blood sugar. Can promote metabolism of digestive system. It has obvious curative effect on hepatitis, gastritis, gastric and duodenal ulcer, diabetes, chronic renal failure, etc.

4. Treating respiratory diseases: the Ganoderma spore powder has spasmolytic and antiasthmatic effects on organ smooth muscle, and can be used for relieving rigidity of muscles and eliminating phlegm, and has therapeutic effect on chronic bronchitis, bronchial asthma, etc.

5. Treatment of neurological disorders: the Ganoderma spore powder has effects of regulating central nervous system, tranquilizing, relieving pain, and improving neurasthenia and insomnia, dizziness, asthenia, gastrointestinal dysfunction, amnesia, anorexia, palpitation, short breath, hyperhidrosis caused by nervous tension and overfatigue.

6. Improving the immune function of the human body: the ganoderma lucidum spore powder can improve the functions of 21692.

7. Anti-aging: the ganoderma lucidum spore powder can eliminate free radicals in vivo, stop lipid peroxidation, protect cells, prolong division generation of passage cells, prolong cell life, promote metabolism, strengthen physique, effectively delay aging, and prolong life after long-term administration.

Astragalus root: huang Qi is sweet in nature and slightly cold in nature, and enters spleen and lung meridians. Has effects in invigorating qi, invigorating yang, consolidating superficial resistance, arresting sweating, inducing diuresis, relieving swelling, promoting fluid production, nourishing blood, removing stagnation, relieving arthralgia, expelling pus, healing sore, and promoting granulation. Can be used for treating deficiency of vital energy, asthenia, anorexia, loose stool, collapse of middle-warmer energy, chronic diarrhea, rectocele, hematochezia, spontaneous perspiration due to exterior deficiency, edema due to qi deficiency, internal heat, diabetes, blood deficiency, hemiplegia, arthralgia, numbness, carbuncle, cellulitis, and intractable ulcer.

Tuckahoe, poria cocos: poria has mild nature, sweet and bland taste, and enters heart, spleen, lung, bladder, triple energizer and stomach meridians. The efficacy is mainly as follows: 1. dampness excreting and diuresis promoting: this herb has mild property and can induce diuresis without damaging qi, so it is the key herb for inducing diuresis and excreting dampness. It is indicated for dysuria, edema, diabetes and stranguria with turbid urine. 2. Strengthening the spleen and stomach: it can tonify spleen, and is indicated for spleen deficiency and stomach weakness syndrome, manifested as poor appetite, constipation, cough with dyspnea due to phlegm and retained fluid, vertigo, etc.. 3. Calming the heart and tranquilizing the mind: it is sweet and bland and enters heart, spleen and kidney meridians. It can be used for treating uneasiness due to heart-spleen deficiency and disharmony between heart and kidney. 4. Strengthening essence and benefiting marrow: it is sweet and tonifying, so it enters spleen meridian. Tonify spleen and qi, strengthen spleen to secrete essence, tonify spleen deficiency, secure essence and check nocturnal emission.

Barbed skullcap herb: mild in nature, pungent and slightly bitter in taste; enter heart, lung, liver and kidney meridians. The efficacy is mainly as follows: 1. clearing heat and removing toxicity: this herb is pungent, slightly bitter and neutral in nature. Has the effects of clearing away heat and toxic materials, and can be taken orally or applied externally. Can not only remove insect poison, but also remove snake venom, and is a good product for sterilizing and diminishing inflammation. It is often used to treat dysentery, swollen and sore throat, innominate toxic swelling, jaundice, tonsillitis, snake bite, furuncle, pulmonary abscess, carbuncle on the back and other symptoms, 2, stop bleeding: the product is neutral in nature, pungent and slightly bitter in taste, and has the effects of clearing heat, removing blood stasis and stopping bleeding. It is commonly indicated for hematemesis, xiuyan blood, hematuria and hemafecia.

Herba Hedyotidis Diffusae: bitter and light taste and cold nature, and can be used for treating carbuncle, swelling, sore, venomous snake bite, abdominal pain due to intestinal abscess, stranguria due to heat-evil, and jaundice due to damp-heat pathogen. Oldenlandia diffusa also has 1. An anti-tumor effect; 2 has antibacterial and anti-inflammatory effects, and can enhance phagocytic function of reticuloendothelial system and phagocytic activity of leukocyte in vivo and in vitro. 3. Inhibiting and killing hepatocarcinoma cell. 4. Affecting the function of T cell, activating T lymphocyte to release interferon, killing tumor cell and strengthening non-specific immunity. 5. Enhancing immunity of organism.

Caulis Marsdeniae Tenacissimae: the root of the glaucescent fissistigma root is used as the medicine-entering part, and the taste is slightly pungent and astringent, and the glaucescent fissistigma root is warm in nature. Enter liver meridian. Has the functions of dispelling wind-damp, dredging meridian, promoting blood circulation and stopping bleeding. Marsdenia tenacissima has slight toxicity, but does not worry about causing adverse effects on the body as long as the Marsdenia tenacissima is taken correctly. The glaucescent fissistigma root contains more effective components, can activate human body cells and promote the generation of protein after being taken into a body, is helpful for improving immunity, can promote blood circulation to remove blood stasis, eliminate dampness and relieve pain, is beneficial to the group of rheumatism diseases, and helps to condition the body and improve the sub-health state by correct taking. Modern research on pharmacological effects: 1. improving immunity. 2. Has antitumor effect.

White peony root: also called Bai Shao, is slightly cold in nature, bitter and sour in taste, entering liver and spleen meridians. The efficacy is mainly as follows: 1. nourishing blood and liver: bitter and sour in flavor, entering liver meridian, can nourish liver blood and soften liver. It is commonly indicated for irregular menstruation and dysmenorrhea. 2. Astringe yin to check sweating: ku sour can nourish blood and ying nutrient, so it can astringe yin to check sweating, usually indicated for spontaneous sweating, night sweat, yellow sweat, etc. 3. Relieving and stopping pain: bitter and sour, slightly cold, entering liver and spleen meridians, can nourish blood and liver, relieve spasm and alleviate pain. It is commonly indicated for abdominal pain, hypochondriac pain, stomach pain, diarrhea, dysentery, etc. 4. Pacify liver yang: bitter can tonify yin, sour can astringe, enter liver meridian, and liver libido can dissipate and astringe, so it can pacify liver yang, and is commonly indicated for liver yang hyperactivity.

Chinese yam: yam is sweet in flavor, neutral in nature and nontoxic, and enters spleen, lung and kidney meridians. Has effects in invigorating spleen, tonifying lung, reinforcing kidney, and replenishing vital essence. It is indicated for diarrhea due to spleen deficiency, chronic dysentery, cough due to asthenia, diabetes, spermatorrhea, leukorrhagia, and frequent micturition. Tonify spleen and stomach, promote the production of body fluid and nourish lung, tonify kidney and astringe essence. Can be used for treating spleen deficiency, anorexia, chronic diarrhea, lung deficiency, cough, asthma, spermatorrhea, leukorrhagia, frequent micturition, and diabetes due to deficiency heat. The bran-parched rhizoma Dioscoreae has effects of invigorating spleen and invigorating stomach. Can be used for treating spleen deficiency, anorexia, diarrhea, loose stool, and leukorrhagia. Modern pharmacological research of Chinese yam: 1. improving immunity. 2. Improving digestive function. 3. Reducing blood sugar and blood fat. 4. Delaying senility. 5. Anti-tumor and anti-mutation effects. 6. Promoting the regeneration and repair of the kidney.

In the traditional Chinese medicine literature, tumors belong to a plurality of disease categories such as 'tumor', 'rock', 'addiction', 'accumulation', 'metrorrhagia and metrostaxis', 'dysphagia', 'ovarian cyst', 'glory', 'tongue bacteria', 'cocoon lip' and the like. Due to various factors such as seven emotions, diet, exogenous pathogenic factors or chronic diseases, the dysfunction of qi, blood and body fluids of viscera, qi, phlegm, blood stasis and heat toxin stagnation and accumulation are caused, and the diseases are mutually affected, the pathogenic factors are exuberant and the healthy energy is deficient after a long time, the tumor develops gradually, and the qi and the blood are increasingly consumed and injured, and finally a serious malignant result is formed. From pathological analysis, qi, phlegm, blood stasis and heat-toxicity are the main symptoms, which are the functional disorders of the excess viscera, while the deficiency of the vital qi is the main symptom, which is the deficiency. Therefore, the treatment method is to give consideration to the deficiency of the original qi for tonifying, and the medicines for clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, eliminating phlegm and promoting diuresis, and softening and resolving hard mass are used in due time. Because the tumor develops continuously, the zang-fu organs are affected, so it is usually combined with tonification and purgation. Especially for patients in late stage, if the tumor has metastasized and healthy qi has declined, the healthy qi should be strengthened as the main indication, qi and blood should be tonified and qi should be tonified as the main treatment, so as to effectively restore the balance of yin and yang of the human body and improve the environment in the organism. Based on the theory, the invention takes the scorpion, the ginseng, the longan, the inonotus obliquus, the lucid ganoderma, the astragalus mongholicus and the poria cocos as monarch drugs (the scorpion is a monarch drug and is recorded as a drug guide due to the special preparation method), and has the effects of detoxifying and tonifying qi, activating blood and strengthening body resistance and treating both principal and secondary aspect of disease. The scorpion can not only prevent tumor, but also enhance human immunity, balance yin and yang and prolong human life; ginseng, longan, chaba, ganoderma lucidum, astragalus membranaceus and Poria cocos benefit qi and strengthen body resistance to tonify spleen deficiency and restore the pivot of rising and falling of middle jiao. Scutellaria barbata, glaucescent fissistigma root and spreading hedyotis herb are used as ministerial drugs for clearing away heat and toxic materials, removing internal pathogenic toxins, assisting the monarch drugs in strengthening body resistance and expelling pathogenic factors from the body. The fried white paeony root, the Chinese yam and the ginger are adjuvant drugs and have the effects of nourishing blood and regulating nutrient, astringing yin and suppressing sweating, tonifying spleen and lung, reinforcing kidney and replenishing vital essence, relieving exterior syndrome and dispelling cold, warming middle-jiao and preventing vomiting, warming lung and detoxifying and removing fish and crab toxicity. Improving the environment in the body, further strengthening the body resistance and leading healthy qi to enter the body. The invention starts from the mechanism of tumor formation, adopts raw materials with different drug properties, and has scientific and reasonable compatibility. The medicines are combined, so that the balance of yin and yang of an organism can be regulated, the immunity of the organism can be improved, the normal physiological function of the human body can be effectively recovered, and the purposes of improving and preventing tumors of the human body are achieved.

In summary, the whole formula has: replenishing qi and blood, regulating yin and yang, promoting blood circulation for removing blood stasis, combating poison with poison, improving immunity, killing cancer cells, and inhibiting cancer cell proliferation.

Compared with the prior art, the invention has the following technical effects:

1. the Chinese medicinal composition is suitable for treating various malignant tumors, such as: brain tumor, liver cancer, esophageal cancer, gastric cancer, skin cancer, etc. The medicine of the present invention is used in treating various malignant tumors, and has determined curative effect, low cost, high safety and reliability.

2. The medicine of the invention has the functions of replenishing qi and blood, regulating yin and yang, promoting blood circulation to remove blood stasis, improving the immunity of organisms, activating the immune phagocytosis system of cells of the organisms, and phagocytosing cancer cells to inhibit the proliferation of the cancer cells. Has obvious inhibiting effect on the growth of human tumor cells, enhances the curative effect of inducing the apoptosis of the tumor cells, lightens the toxic and side effect of the tumor cells, obviously inhibits the growth of the tumor, and further improves the life quality and survival time of tumor patients. The medicine of the present invention has obvious curative effect, less side effect and low cost.

Detailed Description

The present invention will be further described with reference to the following embodiments.

Example 1

A traditional Chinese medicine composition for treating tumors is prepared from the following raw material medicines in parts by weight: 100g of ginseng, 100g of longan, 100g of inonotus obliquus, 100g of lucid ganoderma, 100g of astragalus membranaceus, 100g of poria cocos, 60g of oldenlandia diffusa, 60g of glaucescent fissistigma root, 60g of fried white paeony root and 100g of Chinese yam. The Chinese medicinal composition composed of the raw material medicaments can effectively treat tumors from endoderm in an embryonic period, such as lung tumors, kidney tumors and tumors of a cardiovascular system.

The traditional Chinese medicine composition is prepared into pills, and the specific preparation method comprises the following steps: grinding the raw material medicines into powder with the granularity of 100-200 meshes, mixing the powder into a hard paste with honey, and preparing the pill by mixing the raw material medicines into the hard paste with the addition of the honey. The pill size is 15g per pill.

Example 2

A traditional Chinese medicine composition for treating tumors is prepared from the following raw material medicines in parts by weight: 100g of ginseng, 100g of longan, 100g of inonotus obliquus, 100g of lucid ganoderma, 100g of astragalus membranaceus, 100g of poria cocos, 60g of sculellaria barbata, 60g of glaucescent fissistigma root, 60g of fried white paeony root and 100g of Chinese yam. The Chinese medicinal composition can effectively treat tumors derived from embryonic mesoderm, such as blood tumor, bone tumor and digestive system tumor.

The traditional Chinese medicine composition is prepared into pills, and the specific preparation method comprises the following steps: grinding the raw materials into powder with the granularity of 100-200 meshes, blending the powder into hard paste by honey, and preparing the pill by adding the honey according to the degree of blending the raw materials into hard paste. The pill size is 15g each.

Example 3

A traditional Chinese medicine composition for treating tumors is prepared from the following raw material medicines in parts by weight: 100g of ginseng, 100g of longan, 100g of inonotus obliquus, 100g of lucid ganoderma, 100g of astragalus membranaceus, 100g of poria cocos, 60g of oldenlandia diffusa, 60g of sculellaria barbata, 60g of fried white paeony root and 100g of Chinese yam. The Chinese medicinal composition can effectively treat tumors derived from embryonic ectoderm, such as brain tumor, nervous system tumor and skin tumor.

The traditional Chinese medicine composition is prepared into pills, and the specific preparation method comprises the following steps: grinding the raw materials into powder with the granularity of 100-200 meshes, blending the powder into hard paste by honey, and preparing the pill by adding the honey according to the degree of blending the raw materials into hard paste. The pill size is 15g per pill.

Example 4

A traditional Chinese medicine composition for treating tumors is prepared from the following raw material medicines in parts by weight: 100g of ginseng, 100g of longan, 100g of inonotus obliquus, 100g of lucid ganoderma, 100g of astragalus membranaceus, 100g of poria cocos, 60g of oldenlandia diffusa, 60g of glaucescent fissistigma root, 60g of sculellaria barbata, 60g of fried white paeony root and 100g of Chinese yam. The Chinese medicinal composition composed of the raw material medicaments can effectively treat various tumors.

Example 5

A traditional Chinese medicine composition for treating tumors is prepared from the following raw material medicines in parts by weight: 90g of ginseng, 90g of longan, 90g of inonotus obliquus, 90g of lucid ganoderma, 110g of astragalus membranaceus, 110g of poria cocos, 50g of oldenlandia diffusa, 20g of glaucescent fissistigma root, 70g of fried white paeony root and 110g of Chinese yam.

The preparation method of the Chinese medicinal composition is the same as that of example 1.

Example 6

A traditional Chinese medicine composition for treating tumors is prepared from the following raw material medicines in parts by weight: 110g of ginseng, 110g of longan, 110g of inonotus obliquus, 90g of lucid ganoderma, 90g of astragalus membranaceus, 90g of poria cocos, 50g of glaucescent fissistigma root, 20g of sculellaria barbata, 50g of fried white paeony root and 90g of Chinese yam.

Example 7

A traditional Chinese medicine composition for treating tumors is prepared from the following raw material medicines in parts by weight: 95g of ginseng, 95g of longan, 105g of inonotus obliquus, 110g of lucid ganoderma, 95g of astragalus membranaceus, 105g of poria cocos, 20g of oldenlandia diffusa, 50g of scutellaria barbata, 55g of fried white paeony root and 105g of Chinese yam.

Example 8

The drug comprises a main drug and a guiding drug, wherein the main drug is the traditional Chinese medicine composition for treating tumors in embodiment 1, and the guiding drug comprises millet, noni, chinese yam, ginger, ferment bacteria and adult live scorpions.

The preparation method of the guiding drug comprises the following steps:

step A: washing and airing 500g of millet, 100g of noni, 100g of Chinese yam and 100g of ginger, filling the mixture into a clean jar, adding purified water to submerge the raw materials, adding 150g of ferment bacteria, and standing the sealed jar at normal temperature for at least 3 months to obtain ferment liquid serving as a dispensing guide for later use;

and B, step B: and (3) soaking 10 adult live scorpions in 58-degree white spirit for 1-3 minutes, washing with purified water, adding 30ml of the enzyme solution obtained in the step (A), 30ml of honey and 30ml of fresh orange juice, crushing, and mixing the crushed mixture to obtain the guiding drug.

The taking method comprises the following steps: the pill is taken 1 time a day, 15g each time; the guiding drugs are administered 1 time a day.

Example 9

A medicament for treating tumors, which comprises a main medicament and a guiding medicament, wherein the main medicament is the traditional Chinese medicine composition for treating tumors in embodiment 2, and the guiding medicament and the preparation method are the same as in embodiment 8.

Example 10

A medicament for treating tumors, which comprises a main medicament and a guiding medicament, wherein the main medicament is the traditional Chinese medicine composition for treating tumors in embodiment 3, and the guiding medicament and the preparation method are the same as in embodiment 8.

Example 11

The drug comprises a main drug and a guiding drug, wherein the main drug is the traditional Chinese medicine composition for treating the tumor in embodiment 4, and the guiding drug comprises millet, noni, chinese yam, ginger, ferment bacteria and adult live scorpions.

The preparation method of the guiding drug comprises the following steps:

and B: and (3) soaking 10 adult live scorpions in 58-degree white spirit for 1-3 minutes, washing with purified water, adding 30ml of the enzyme solution obtained in the step (A), crushing, and obtaining a crushed mixed solution, namely the guiding drug.

The taking method comprises the following steps: the pill is taken 1 time a day, 15g each time; the guiding drugs are administered 1 time a day. .

(one), pharmacological toxicity test

1. Drug accumulation toxicity test

The method comprises the following steps: 10 Kunming mice are selected, half of each mouse, 6-8 weeks old, 20 +/-2 g of body weight and provided by the experimental animal center in Henan province. The experimental preposed animal is adapted to the indoor environment for three days at the room temperature of 18-25 ℃ and the relative humidity of 45-65%. The mice were gavaged once a day with the bolus (the bolus was melted with purified water into a paste) and the drug infusion prepared from the Chinese medicinal composition of example 11 of the present invention, and the gavage amount of the mice was calculated as kg. Beginning to fill the stomach with 3g/kg.bw, 10 times of the daily clinical dose for the adult (15 g of the daily clinical dose for the adult, 1 time per day, 0.3g/kg.bw, the adult body weight is calculated as 50 kg), and then gradually increasing the daily stomach filling dose to 30g/kg.bw according to the regular dosage increasing method, and weighing once every 5 days for 100 times of the daily clinical dose for the adult.

And (4) testing results: all the animals normally survive without death phenomenon and obvious toxic reaction, and the results of detecting organs such as heart, liver, spleen, lung, kidney, adrenal gland and the like show that: none of the above organs had obvious lesions.

2. Acute toxicity test of drugs

The method comprises the following steps: 10 Kunming mice are selected, half of each mouse, 6-8 weeks old, 20 +/-2 g of body weight and provided by the experimental animal center in Henan province. The experimental preposed animal is adapted to the indoor environment for three days at the room temperature of 18-25 ℃ and the relative humidity of 45-65%. The mice were gavaged with a bolus (the bolus is fused into paste with pure water) prepared from the traditional Chinese medicine composition of example 11 of the present invention in an amount 500 times the clinical daily dose of adults and a guiding drug once, and the gavage amount of the mice was calculated according to kg of body weight (kg.bw), and the gavage dose was 150g/kg.bw. The reaction status, toxic symptoms and death of the animals were immediately observed for 7 days.

And (4) observing results: all animals are kept healthy and move freely, and no abnormality and toxic reaction are found in food intake, drinking, hair and excrement.

In conclusion, the results of the drug accumulation toxicity test and the drug acute toxicity test prove that the traditional Chinese medicine composition prepared by the invention has good safety and low toxicity.

(II) clinical data and experiments of treating various tumors by using the medicament for treating tumors provided by the invention:

1. general clinical data and typical cases

The judgment standard of the patient effect is as follows: the pain symptom disappears, the hypodynamia is obviously improved, the jaundice is relieved, the symptoms of hematuria, hemafecia and high intracranial pressure nausea and vomiting are relieved, and various symptoms and signs after radiotherapy and chemotherapy are obviously improved. Improvement standard: the symptom sign of the obvious judgment standard disappears, and the local tumor is reduced by 1/3-1/2, so that the function is recovered. One month of treatment is 1 course of treatment.

For years, 79 patients with lung cancer and renal cancer from embryonic endoderm are treated by using the traditional Chinese medicine composition and the pills prepared by the traditional Chinese medicine composition, and matched with guiding drugs (embodiment 8), 48 patients with lung cancer and renal cancer are treated by using 48 patients with male cancer, 31 patients with female cancer, 39 patients with the minimum age and 82 patients with the maximum age, 43 patients after surgery and 36 patients without surgery are treated by using the pill and the guiding drugs for treating tumors of the invention for 3 treatment courses or more than 49 patients, 2 treatment courses of the pill and the guiding drugs for treating tumors of the invention for 19 treatment courses, 1 treatment course of the pill and the guiding drugs for treating tumors of the invention, and 2 patients die. 76 cases of the disease were improved, 79 cases of the disease were shown, and 2 cases of the disease died from pulmonary embolism and myocardial infarction respectively.

Typical cases are:

1. some Lu, man, 68 years old, necao county, shandong province, in 2 months of 2015 for "chest pain nearly one year, chest distress and cough for a while. "visit doctor in Cao county hospital, CT examination: the anterior segment of the left lung has a mass of about 60 × 59mm, the left hilum lymph node is significantly enlarged, the ribs near the mass have signs of destruction, the left pleura is thickened, and pleural effusion. The pathological diagnosis is large cell lung cancer following the lung lobe resection. Chemotherapy was given once, but chest pain and chest tightness were still not relieved. By introducing the introduction, the chest pain is obviously relieved after the medicine is taken for one month, and the continuous taking of 3 treatment courses is improved.

2. The Yao is a certain herb, male, 80 years old, and people in Laiwu city, shandong province, in 5 months in 2018, the disease indicates chest pain is half a year, and chest distress is accompanied by cough for two months. "visit the doctor in the national hospital of Laiwu city for chief complaints, CT examination: the lower lobes of the right lung are frequently nodular with a large mass located at about 58 x 56mm in the hilum, with profound enlargement of the right hilum lymph nodes, thickening of the right pleura, pleural effusion, and scattered metastases in CT brain. Performing bronchoscopy biopsy, and performing pathological diagnosis on the lung cancer. Chemotherapy is given once because the cancer cannot be operated near the phylum of the lung, but chest pain and chest distress cannot be relieved. By introducing the introduction, the chest pain is obviously relieved, the cough and the chest distress are improved after the medicine is taken for one month, and the continuous taking of 3 treatment courses is improved. One year later, the original right pulmonary lump is rechecked to become smaller than 29X 26mm, and the brain metastasis disappears and only disperses at the calcification points.

3. Congratulate a certain person, male, 66 years old, changsha city Anhua county. The doctor mainly complains about chest pain and cough for 3 months in 27 months in 2019, and the clinic number is as follows: 202104273023, ct examination report: anterior segment mass of the right superior lung lobe of about 43 × 58mm, evident right supraglottic lymph nodes, inflammatory exudation between mass and right supraglottic. In a local lobectomy, the pathological diagnosis is small cell lung cancer. After the operation, the bone metastasis of the whole body and the liver metastasis are found in half a year. The medicine guide and pills are taken at the beginning, and 3 treatment courses are improved after continuous taking. In the present year, the lung and liver metastasis appeared in small nodular form in CT examination, and the bone metastasis disappeared in ECT bone scan.

4. One certain beam, male, 68 years old, schchang city, south of Henan province. The last year of 2020, 9 and 3 days, the chest distress and chest pain with cough is about one year. "clinic CT examination report for the visit of the first subsidiary hospital of Zhengzhou university: a53-by-60mm lump is placed just below the right hilum, and the tissue is removed by bronchoscopy following admission, and the lung adenocarcinoma is diagnosed by biopsy. Since the lung cancer mass surrounds the great vessels of the lung portal, the operation cannot be performed, and chemotherapy is given once according to the schedule of a tube bed doctor. The chemotherapy has great response, frequent vomiting, general weakness and hair loss, but chest pain can not be controlled, and insomnia is difficult to sleep. After the product is taken for one week, the pain is obviously relieved after the product is taken for about one month, and the patient feels better than normal after taking the product for three months, so that the daily work is recovered. In order to consolidate the curative effect, the patient takes the medicine for three months after taking the medicine in a slightly reduced amount. After half a year CT examination only 2.5 x 2.8mm of right pulmonary nodules, which had become calcified.

6. In 7 days 2 and 7 days 2 in 2021, a person who is a man in 73 years old, xuchang city, henan province in a certain week is in a state of' intermittence with abdominal pain for more than 2 months, accompanied by labored urine and facial edema for a week. "mainly complain the first subsidiary hospital of Zhengzhou university and see doctor color Doppler and CT examination: two subcapsular solid masses, one approximately 20 x 1.9mm larger, were subcapsular solid masses with heterogeneous and hyperechoic solid masses. There are multiple hyperechoic masses in the prostate, the larger of which is about 3.5 x 3mm, protruding toward the bladder. The doctor managing the bed talks to the family members of the patient: the cancer of the kidney and the prostate reaches the late stage, the operation cannot be taken away, and only the upper and lower tubes are arranged in the ureter to solve the problem of urination of the kidney of a patient. After the operation incision is healed, the problems of abdominal pain and the like cannot be relieved by performing chemotherapy once by the family members with the doctors. The disease recurs soon, the ureteral drainage tubes at the two sides of the waist seep a lot of liquid, the pain of the abdomen of the patient is not like to go, and the dyscrasia of the advanced cancer enables family to see that the patient will come into life soon. When the patient takes the product, the two tubes at the back part do not seep outside for about more than ten days, the pain is obviously relieved, and the patient can take the product for 3 months.

For years, 88 patients with gastric cancer, intestinal cancer and liver cancer from embryonic mesoderm in an embryonic period, 52 patients with gastric cancer, intestinal cancer and liver cancer in men, 36 patients with female cancer, 28 patients with minimum age and 92 patients with maximum age, wherein 49 patients after surgery and 39 patients without surgery take 3 pills and guiding medicaments for treating tumors, 55 patients take 27 pills and guiding medicaments for treating tumors, and 1 treatment course of 1 pill and guiding medicament for treating tumors in the invention dies 3 patients. 85 cases of the patients are improved, 88 cases of the patients have obvious effect, and 3 cases of the patients die from the family and refuse to treat the patients and the patients with myocardial infarction.

Typical cases

1. Xi-somewhat, male, age 39, official, xijin county, shandong province, in 7 months of 2014 "epigastric pain, emaciation for half a year, with anorexia and hypodynamia for a month. "visit hospital in Xiujin county for chief complaints, CT examination: the lesser curvature of the stomach has a large mass 62 x 59mm, several nodules of the liver, a large mass 33 x 32mm, and a swollen celiac lymph node. Doctors recommend to excise the primary focus of stomach cancer and then carry out chemotherapy. The patient is hospitalized and still cannot stop the process of cancer recurrence, the nodules of the liver obviously grow up, and ascites and epigastric pain appear to make the patient sleep hard all the night. The cachexia in the advanced stage of cancer makes the patients progress the regression in advance. By introducing the introduction that the anti-tumor product is taken as a guiding drug and a pill, the pain is relieved when the anti-tumor product is taken for one month, the pain is relieved after the anti-tumor product is continuously taken for 3 months, and then the patient continues to take the anti-tumor product for 3 months for strengthening the curative effect. In 2015, the patient recovered to work again.

2. One old man, male, 68 years old, mianchi county, sanmenxia, henan province, in 13 months 6 in 2021 for "jaundice, epigastric discomfort, anorexia for half a month. "mainly complain to go to the department of hospitalization in traditional Chinese medicine Mianchi prefecture, hospitalization number 202106311, color Doppler report: the hepatic portal 60 × 35mm hyperechoic, the pancreatic head visible as a hypoechoic about 25 × 25mm, the posterior peritoneal membrane visible as multiple hypoechoic, the larger of which was 33 × 13mm. And (3) CT examination: the liver is seen with multiple low density shadows, the larger one is located at the hepatic portal, about 60 x 45mm, the right lower lung is seen with two rounded nodules about 45mm in diameter, and the liver biopsy pathology report is: hepatobiliary cell carcinoma. The medicated core and the pill of the product are directly taken because of no operation, jaundice gradually diminishes after one month, and jaundice basically diminishes after continuous taking for 3 months. Because the cancer of liver, gallbladder and pancreas is called king of cancer, the patient can take the medicine for half a year.

3. One certain woman in the family of Liangjiao, 65 years old, renxian county, shaosuan city, guangdong province, in 2021, 4 months and 9 days, the liver region pain, anorexia and hypodynamia are two months. "visit to the first affiliated hospital of river university for main complaint, CT examination: multiple nodules in the liver, 55 × 52mm in the larger, one ground hyaline nodule in the posterior segment of the left superior pulmonary lobe tip, size about 11 × 9mm, multiple nodule high density shadow in the double kidney, and multiple slightly larger lymph node shadow beside the larger 50 × 40mm double iliac blood vessel. The uterus had a slightly lower density of shadows, larger on the anterior wall, about 68 × 58 × 51mm. Because the cancer is widely transferred and can not be removed by operation, the tube bed doctor can not take effect after repeated chemotherapy, and the pain and the ascites hydrothorax are aggravated. After the guiding drug and the pill of the product are taken in 6 months, the pain is relieved after one month, the patient does not have pain after taking the medicine for 3 months continuously, and the ascites does not increase any more. After the patient insists on consolidation for 3 months, the patient is improved.

4. One of pottery, women, 64 years old, laiwu City in Shandong province, 11 months in 2015, the recipe is to show that "stool is flat and thin with blood with lower abdomen and anal pain for two months. "refer to the doctor in the department of TCM in Laiwu, CT examination: the mass 58 x 56mm above the anterior wall of the rectum had broken through the serosal basal layer and had an involvement of the posterior wall of the uterus, with large pelvic lymph nodes. The lung has different sizes and is scattered on nodules, the larger is 35X 33mm, and the pathological diagnosis of the colorectal adenocarcinoma is the colorectal adenocarcinoma by taking the lung metastasis of the rectal cancer into consideration. Because extensive metastasis is inoperable, hospitals are given chemotherapy several times, but pain and hematochezia cannot be controlled. The pain is obviously relieved and the hematochezia is also obviously improved after the guiding drug and the pill for treating the tumor are taken for one month by people. The treatment course is improved after continuous taking for 3 times. In order to consolidate the curative effect, the patients should stay on the medicine for two months, and after one year, the rectal mass is rechecked to shrink to 25 × 23mm, and obvious calcification is generated.

5. In the case of a certain person in the week, women are 60 years old, and the patient is suffered from the lower abdomen tenesmus and pain for two months in 2019, 9 and 1 month. "the physician has a diagnosis in Yuzhou city hospital, and ultrasonic examination finds that the pelvic cavity has substantial mass and large amount of ascites. Hospitalization was followed with hospitalization No. 0000612095, post admission CT exam: pelvic solid space occupying, about 68 x 65 x 62mm in size, large fluid accumulation in the abdominal cavity, and several swollen lymph nodes around the left iliac vessels. Following ultrasound-guided biopsy, the pathology was reported as ovarian granulosa cell carcinoma. No treatment is carried out in a hospital, the guiding drug and the pill of the product are introduced to be taken, and the lower abdomen pain disappears after the guiding drug and the pill are taken for one month, so the improvement is achieved after the guiding drug and the pill are taken for one month. The ultrasonic pelvic cavity mass is obviously reduced after 3 months of reexamination, and the patient is only taking the medicine for two months due to economic reasons and is healthy nowadays.

5. In 4 months in 2021, wang from a certain Wang, male, 92 years old, or Jiangxi province, the aged trunk leaves the resting part, because of "bloody stool with lower abdomen pain and abdominal distension". "Hospital number 1334760 for the patients who complain in the hospitals of the people in Jiangxi province, CT examination: see lumps 66 × 62mm in the middle section of sigmoid colon, abdominal and retroperitoneal lymph nodes, multiple nodules in the liver, a maximum of 39 × 35mm, and moderate fluid accumulation in the abdominal cavity. The enteroscope biopsy pathology is reported as sigmoid adenocarcinoma. Considering that patients are high in age and have extensive metastasis, tube bed doctors decide to treat the chemotherapy, only one course of treatment causes patients to feel death frequently, and the patients relapse quickly, have increased ascites due to pain, and have a firm opposition to the chemotherapy by themselves. The guiding drug and the pill of the product are taken in 8 months, the abdominal pain and the abdominal distension are relieved after one month, the hematochezia is reduced, and the improvement is better after continuous taking for 3 months. In order to consolidate the curative effect, the patient takes the medicine for 6 months and is recovered.

(III) for years, the traditional Chinese medicine composition and the pills prepared by the traditional Chinese medicine composition are used together with guiding drugs (embodiment 10) to treat 26 patients with brain glioma, subcutaneous alveolar sarcoma and breast cancer from embryonic epiblast in embryonic period, 14 patients with male, 12 patients with female, 5 years of minimum age and 72 years of maximum age, 19 patients after operation and 7 patients without operation, 3 treatment courses of the pill and the guiding drug for treating tumor of the invention to more than 20 patients, 2 treatment courses of the pill and the guiding drug for treating tumor of the invention to 5 patients, 1 treatment course of the pill and the guiding drug for treating tumor of the invention to 1 patient, and 1 patient died. Of these, 24 cases were improved, 26 cases were significantly effective, and 1 case died due to the patient being on-hold.

Typical cases

1. In 3 months in 2019, a certain Wu, male, 39 years old, changyuan county, anyang, the patient starts to have headache, nausea sometimes occurs, the patient is not taken according to cold fever and the like in a local health town hospital, then brain CT is carried out, the suspected brain has space occupying lesion, nuclear magnetism is carried out to confirm the diagnosis as brain tumor, the first subsidiary hospital of Zhengzhou university is further examined, and the confirmed diagnosis is as follows: brain glioma, and performing surgical excision treatment; headache, nausea, dizziness and poor appetite disappear after the operation. After the patient catches a cold in 6 months in 2020, the patient has headache, nausea and hypodynamia, sometimes has insomnia and memory loss, and after the patient visits the 301 Hospital in Beijing City, nuclear magnetic examination is carried out, and the patient is considered to have more than 1 year after the operation, relapse of primary brain glioma and ineffective treatment, and then the patient visits the first affiliated Hospital in Zhengzhou university (the original operating Hospital) to find the primary doctor to visit, and the doctor says that: the brain glioma is recurrent after the operation, and the conservative treatment is recommended. The doctor visits the patient at the same place through introduction, and the treatment scheme adopted according to the condition of the patient is as follows: the patient can try the guiding drug and the pill for treating the tumor, after continuously taking the guiding drug and the pill for 1 treatment course, the symptoms are relieved, the vomiting is avoided, the spirit is improved, and the effect is obvious; after continuously taking for 2 courses, the symptoms are eliminated, and the brain tumor body atrophy disappears in CT treatment, so that the patient is improved.

2. One of Zhao, man, 48 years old, zheng Zhou City, henan province, entrepreneurs, in 5 months of 2015 for "stool with purulent blood, anal swelling and pain for a long time. "visit the first subsidiary hospital of Zhengzhou university for chief complaints, CT examination: the mass at the upper end of the rectum was 69 × 58mm, the lymph nodes were enlarged in both iliac vessels on both sides, the abdominal cavity and retroperitoneal lymph nodes were enlarged, and the liver was scattered with multiple nodules and a maximum of 55 × 53mm. Hospitalization for rectal cancer resection is immediately performed, pathological diagnosis of rectal acinar granular cell carcinoma is performed after surgery, and chemotherapy is given for multiple times. Relapse after discharge soon, headache and abdominal distending pain are frequently felt, and the patient is subjected to CT examination: the largest nodules of the liver are enlarged, the head is scattered on the multiple nodules, the size is about 39X 36mm, the size is as small as rice grains, and the liver metastatic cancer and the brain metastatic cancer are diagnosed in hospitals. After repeated hospitalization, chemotherapy and radiotherapy, the effect can not be achieved, patients spend more than three hundred thousand in 3 years, the dyscrasia state is achieved, various nutrients are expected to be maintained, wives are not expected to treat diseases by other means, and the own patients suffer from depression and have the suspended beams. When the patient was admitted to the first affiliated hospital of zheng zhou university at the 15 th admission, the patient always occupied the ICU's bed, and the nurse agreed to the child to pull the patient back home to remain alive. After returning to the original, the patient is introduced and lifted to the original and takes the guiding powder and the pills of the product, the patient can walk to take the medicine for taking the medicine after taking for one week, the symptoms are obviously improved after one month, the pain is relieved, the patient can feel like a normal person after taking for 3 months, the enterprise of the patient starts to manage the patient again, and the patient can take the medicine for 6 months better.

3. When a certain woman is aged, 59 years old, and people of Zheng Zhou city, henan province, the patient complains about the diagnosis in the central hospital of Zheng Zhou city in 11 and 25 months in 2020 that the lump on the left breast occasionally stabs for two weeks, and the physician in charge sees that the lump is located in the upper outer quadrant and the texture is hard to touch. And (3) making a color ultrasound examination report: the lateral superior lump in the left breast is irregular in shape, about 56 × 52mm in size, and several lymph nodes in the lateral and left axillary fossa are enlarged. The pathological diagnosis of the local aspiration biopsy is breast malignant tumor, and the ECT examination reports a plurality of bone metastases. The primary focus is removed, breast cancer radical operation is performed, chemotherapy is performed after operation, but the cancer recurs after 3 months, a lump grows at the original incision, the lump grows at the contralateral breast, the lung also finds that the lump spreads on the nodule, the lump in the breast and the bone of the whole body continuously pain, and the patient feels no pain. By introducing the guiding medicine and pills, the pain of the whole body is relieved after the medicine is taken for one month, the package blocks which can be touched by hands are obviously reduced, and the improvement of continuous taking for 3 months is achieved. The patient takes the product for two months to consolidate the curative effect, and the product is healthy in life at present.

4. Li in Henan province, 5 years old, living in Zheng Zhou city, henan province, in 2021, 4 months and 18 days, it was said that "cough occurred on the left chest pain for a week. "Hospital diagnosis in Henan province tumor hospital, since the left subcutaneous tumor excision of neck and back was performed half a year before the infant patient, the pathological diagnosis was alveolar sarcoma of neck and back, and the doctor also performed corresponding chemotherapy according to the pathological diagnosis. The CT examination finds that: the right upper lung has multiple nodules, mostly like peanut kernels, and the whole lung is in the shape of millet granules. Then the patient is hospitalized with a number of 0000612095, and is given chemotherapy, and the illness state of the children is repeated after the patient is discharged. We have found by introduction that the dosage of the drug guiding substances and the pills of the product is three fifths of that of adults. After the medicine is taken for one month, cough and chest pain are obviously relieved, discomfort symptom disappears after the medicine is continuously taken for 3 months, curative effect is continuously consolidated, the medicine is taken for 3 months, and the left lung nodules become small and the millet-shaped nodules disappear after the CT is reviewed.

5. In a certain model, a woman is 59 years old and 1 month and 5 days 2021, the growth speed of multiple lumps on both sides of the breast is found to be accelerated, the hardness and the pain come to the 301 hospital of the liberty military, mitsuya City, and the diagnosis is carried out by CT examination: see double lung nodules, large about 56 x 55mm, and liver also has multiple nodules, maximum about 35 x 33mm. The patient lives in Yangzhou six years ago, and because the early breast cancer is found, the breast-protecting tumor resection is performed in the first national hospital in Shanghai city, the standard chemotherapy is performed after the operation, and the patient has no discomfort for six years, and the breast malignant tumor is reported to the pathological report of the mass puncture biopsy of the patient by a doctor. The chemotherapy is standardized for half a year after hospitalization, and the tumor recurs after two months of drug withdrawal, so that the growth speed is higher. A large amount of liquid is accumulated in the pleuroperitoneal cavity, and the lump in the breast, the ulcer and the ulcer can not be healed. Bone metastasis is seen in ECT bone scan, and the patient has lump pain and general bone pain, and is analgetic by morphine-like medicine. Chest distress and abdominal distention, insomnia at night, and incapability of eating food, the patient has no strength to lie in bed and turn over. The pain is obviously relieved after the product is taken for half a month by introduction, the morphine analgesics are basically stopped taking, the abdominal distension and chest distress are relieved earlier, and the patient can get up and get out of bed by himself. The patient gets better and gets better, feels chest distress, palpitation and shortness of breath after one-time bed getting-off activity when the patient takes the medicine for nearly 30 days, and is immediately sent to the third-generation 301 hospital for rescue, and finally the heartbeat is stopped due to respiratory failure. The possibility of pulmonary embolism caused by the thrombus shedding of the lower limbs is inferred to be high when the patient lies in bed for a long time.

In conclusion, the invention starts from human tissue embryology origins and tumor pathogenesis, adopts raw materials with different drug properties, has scientific and reasonable compatibility, and can regulate the dynamic yin-yang balance of the organism, improve the immunity of the organism, effectively recover the normal physiological function of the organism and achieve the purposes of treating the tumor and preventing the recurrence and the metastasis of the tumor by combining the raw materials.

The above-mentioned embodiments are merely preferred embodiments of the present invention, which are merely illustrative and not restrictive, and it should be understood that other embodiments may be easily implemented by those skilled in the art by means of replacement or modification according to the technical contents disclosed in the specification, and therefore, all changes and modifications that come within the spirit and technical conditions of the present invention should be included in the claims of the present invention.

Claims

1. The traditional Chinese medicine composition for treating tumors is characterized by being prepared from the following raw material medicines in parts by weight: ginseng, longan, inonotus obliquus, lucid ganoderma, astragalus, tuckahoe, fried white paeony root, yam and at least two of oldenlandia diffusa, glaucescent fissistigma root and barbed skullcap herb.

2. The traditional Chinese medicine composition for treating tumors according to claim 1, is prepared from the following raw material medicines in parts by weight: 90-110 parts of ginseng, 90-110 parts of longan, 90-110 parts of inonotus obliquus, 90-110 parts of lucid ganoderma, 90-110 parts of astragalus membranaceus, 90-110 parts of poria cocos, 50-70 parts of fried white paeony root, 90-110 parts of Chinese yam, and at least two of 20-70 parts of oldenlandia diffusa, 20-70 parts of glaucescent fissistigma root and 20-70 parts of sculellaria barbata.

3. The traditional Chinese medicine composition for treating tumors according to claim 1, is prepared from the following raw material medicines in parts by weight: 100 parts of ginseng, 100 parts of longan, 100 parts of inonotus obliquus, 100 parts of lucid ganoderma, 100 parts of astragalus membranaceus, 100 parts of poria cocos, 60 parts of fried white paeony root, 100 parts of Chinese yam and at least two of 60 parts of oldenlandia diffusa, 60 parts of glaucescent fissistigma root and 60 parts of barbed skullcap herb.

4. The traditional Chinese medicine composition for treating tumors according to any one of claims 1 to 3, which is prepared into a clinically acceptable pharmaceutical preparation according to a conventional traditional Chinese medicine preparation method.

5. The traditional Chinese medicine composition for treating tumors according to claim 4, wherein the pharmaceutical preparation is a pill, a tablet, a powder or a capsule.

6. The traditional Chinese medicine composition for treating tumors according to claim 5, wherein the preparation method of the pharmaceutical preparation comprises the following steps: grinding the raw material medicaments into powder of 100-200 meshes, mixing the powder with honey into paste, and preparing the paste into pills, tablets, powder or capsules.

7. The medicine for treating the tumor is characterized by comprising a main medicine and a guiding drug, wherein the main medicine is the traditional Chinese medicine composition for treating the tumor according to any one of claims 1 to 3, and the guiding drug comprises millet, noni fruit, chinese yam, ginger, ferment bacteria and adult live scorpions.

8. The drug for treating tumors according to claim 7, wherein the preparation method of the drug guiding comprises the following steps:

step A: cleaning millet, noni, chinese yam and ginger, airing and filling into a clean jar, adding purified water to submerge the raw materials, adding ferment bacteria, and placing the sealed jar at normal temperature for at least 3 months to obtain ferment liquid serving as a dispensing guide for later use;

and B: soaking adult live scorpions in white wine for more than 1 minute, washing with purified water, adding the enzyme solution obtained in the step A, crushing, and obtaining a crushed mixed solution, namely the guiding drug.

9. The drug for treating tumor according to claim 8, wherein honey and fresh orange juice are also added during the pulverization in the step B.

10. The drug for treating tumor according to claim 9, wherein the preparation method of the drug guide comprises the following steps:

step A: washing and airing 40-60 parts of millet, 5-20 parts of noni, 5-20 parts of Chinese yam and 5-20 parts of ginger, filling the mixture into a cleaning jar, adding purified water to cover the raw materials, adding 10-20 parts of ferment bacteria, and placing the sealed jar mouth at normal temperature for at least 3 months to obtain ferment liquid serving as a dispensing guide for later use;

and B: and (3) soaking 10 adult live scorpions in 58-degree white spirit for more than 1 minute, washing with purified water, adding 30ml of the enzyme solution obtained in the step (A), honey and fresh orange juice, crushing, and mixing the crushed mixture to obtain the guiding drug.