CN102318680A - Liquid composite acidity regulator used in calf and lamb milk replacer - Google Patents
Liquid composite acidity regulator used in calf and lamb milk replacer Download PDFInfo
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Abstract
The invention relates to a liquid composite acidity regulator used in a calf and lamb milk replacer, belonging to the fields of animal nutrition of animal science disciplines and forage sciences. The liquid composite acidity regulator provided by the invention is prepared by taking formic acid, hydrochloric acid and citric acid as raw materials through a scientific composition. The liquid composite acidity regulator is used in calf and lamb milk replacer emulsion so that the pH value of the emulsion is reduced to 5.0-5.5. The liquid composite acidity regulator can be added when the milk replacer is fed to calves and lambs. The liquid composite acidity regulator is convenient to prepare and use. By using the liquid composite acidity regulator, the growth performance of young animal can be improved; the blood gas index can be improved, therefore, the growth and the development of the calves and the lambs can be improved. By means of the application of the liquid composite acidity regulator used in the calf and lamb milk replacer disclosed by the invention, the visible economic benefit and ecological benefit can be brought about in the animal husbandry, in particular dairy cow and meat sheep cultivation industries.
Description
[technical field]
The present invention relates to a kind of preparation that contains the liquid combined acidity conditioning agent of organic acid and inorganic acid, when feeding calf or lamb, be used to reduce the pH value of its milk replacer emulsion, belong to herding subject Animal nutrition and forage science field.The invention still further relates to the needed raw material type of obtaining liq combined acidity conditioning agent, compound method and method for using.
[background technology]
Birth and wean (break off breast milk, feeding milk replacer) to children calf in age and lamb be a kind of huge stress.The digestive system development imperfection of calf and lamb at that time, gastric acid secretion is not enough, causes digestive enzyme activity to descend, and degradation problem under the digestion power shows symptoms such as diarrhoea in appearance, finally causes undergrowth, even occurs dead.Reduce the pH value of milk replacer emulsion, can increase acidity in the calf abomasum in theory, improve digestive enzyme activity, help the growth of beneficial bacteriums such as the interior lactic acid bacteria of enteron aisle, suppress the breeding of harmful bacterium such as Escherichia coli, keep the micro ecology of gastrointestinal tract balance.
1. the influence of cub alimentary canal acidity imbalance
The imbalance of calf, lamb alimentary canal acidity can be grown to it, physiology produces a series of harmful effect, and 1. be mainly reflected in influences the digestive ferment secretion with active.Alimentary canal acidity is one of principal element that influences digestive ferment secretion and activity.Zhang Xinru etc. (2003) point out that many digestive ferments are active higher in sour environment, and for example, pepsic optimum pH scope is between 2～3.5, and activity can weaken even inactivation when the pH value is higher than 4.Zhang Hongfu etc. (2002) also think, intestinal contents acidity can influence the secretion of intestines endoenzyme etc. with active, thereby directly has influence on digesting and assimilating of feed.2. influence alimentary canal normal flora structure.Alimentary canal acidity is the important environmental condition of alimentary canal microorganism existence.The field planting of intestines and stomach microorganism all receives the influence of alimentary canal acidity with growing; When acidity improved, the beneficial bacterium quantity such as Bacillus acidi lactici of appropriate acid environment reduced, and were adapted at harmful bacterium of surviving under the condition of pH 6～8; Like pathogens such as Escherichia coli, Salmonella, staphylococcus, clostridium; Quantity then increases, and is not at this moment supplied with bacterial growth in a large number by the nutriment of digestion, absorption in the feed ingredient, and this has just caused a large amount of propagation of above-mentioned pathogen.Test shows that strain Escherichia coli can be proliferated into the colony of 4,300,000,000 thalline rapidly in the 24h under the adapt circumstance condition, and this can cause the outburst (Zhang Xinru etc., 2003) of weanling pig stage oedema.
2. add the meaning of acidity regulator in the milk replacer
2.1 milk replacer adds the actual feeding effect of acidity regulator
The research of the pH value of adjustment milk replacer starts from the twentieth century seventies (Woodford etc., 1987), is a kind of byproduct that Holland produces Gouda cheese at first.In the Europe and the U.S., use the acidifying milk replacer feed calf very general (Jaster etc., 1990).The acidifying milk replacer (acidified milk replacer) of feeding may make the fresh keeping time of milk replacer emulsion reach 3 days, stops the quick breeding of enteron aisle pathogeny microorganism simultaneously, and increases the frequency of searching for food greatly, promotes digestion (Erickson etc., 1989).Some appear subsequently with the experimental study of acidifying milk replacer as daily ration; On the acidifying milk replacer basis of feeding, inquire into individual feeding or group feeding mode like (2007) such as (1988a), Hepola such as Richard, bucket is raised and the feeding bottle influence of mode to calf growth, the behavior of searching for food of feeding.Domestic still planless in this regard research is summed up external report and can be known, in milk replacer, uses acidity regulator to mainly contain several respects advantage:
1. prevent that the milk replacer emulsion from becoming sour rotten
The largest benefit of acidifying is to prevent to become sour rotten, the milk replacer emulsion was preserved about 3 days, thereby save labour (Richard etc., 1988b; Sahlu etc., 1992).Woodford etc. (1987) have used the acidifying milk replacer of pH 5.27, are contrast with one day twice conventional milk replacer of feeding, and research freedom is searched for food the calf of acidifying milk replacer to the digestibility of diet nutrient material and the pH value of utilization rate, feed intake and abomasum content.Test is found; The acidifying milk replacer of feeding can reduce calf abomasum and excrement pH value; And but apparent digestibility and absorbed nitrogen that two processing modes do not influence dry, fat, nitrogen retain rate, and the acidifying milk replacer of therefore feeding can adopt the free choice feeding mode, and prevent that emulsion is rotten.
2. reduce intestines and stomach pH value, regulate archenteric flora, thereby reduce the diarrhoea incidence
Yanar etc. (2006) in the ratio of birth weight 8% to calf feed the acidifying milk replacer (acidified milk replacer, AMR) or conventional milk replacer.Its AMR has added formic acid in conventional milk replacer, make ph value of emulsion be reduced to 4.8.The average daily gain of calf, dry matter intake do not have difference in the test, and AMR organizes full phase feed conversion rate better (P＜0.05), and the most outstanding is that the stools scored of 4～17d (P＜0.05) and diarrhoea fate (P＜0.01) reduce.Its reason possibly be that low pH value milk replacer can reduce calf alimentary canal pH value; Control and reduced colibacillary propagation in the alimentary canal, promoted the wherein growth of lactic acid bacteria (Nocek etc., 1986); Show influence, thereby reduce the diarrhoea incidence of calf archenteric flora.The relatively more outstanding effect of AMR reduces alimentary canal pH value often, and promotion digestion reduces infectious disease, especially the calf before 3 ages in week is acted on more obviously (Jaster etc., 1990).
3. improve feed conversion rate, reduce the trophism diarrhea incidence
Yanar etc. (2006) feed to calf and have measured calf body weight, ADG, body length, height, chest measurement, chest depth behind the AMR (pH=4.8), calculate hay simultaneously, open foodstuff, milk replacer dry matter intake and total solids feed intake.Test confirms that AMR does not all make significant difference to above index, but has improved 0～6 monthly age feed conversion rate, and the ratio that the diarrhoea fate accounts for total fate reduces, and wherein 4～17d is reduced to 2.85%, 4～35d from 14.10% and is reduced to 1.65% from 8.36%.
2.2 the pH value of acidifying milk replacer and the acidity regulator kind of using
The research to acidity regulator in the lactation calf milk substitute at present abroad has, and its ph value of emulsion is (Netka etc., 1962 in 4.80～5.45 scopes; Nocek etc., 1986; Woodfood etc., 1987; Erickson etc., 1989; Jaster etc., 1990; Sahlu etc., 1992; Davis etc., 1998; G ü ler etc., 2006; Yanar etc., 2006; Hepola etc., 2007).The pH value of the AMR that uses always in American-European the production is greatly about 5.2, and the most of interpolation is organic acid, for example citric acid, formic acid or propionic acid (Nocek etc., 1986; Jaster etc., 1990; Sahlu etc., 1992), and mostly its milk replacer raw material is newborn source property.Contain the lactose milk products generation lactic acid that in animal gastrointestinal tract, can ferment, thereby improve intestines and stomach acidity.And China is because the dairy products raw material sources are not enough; Calf, the lamb milk replacer raw material of development have to adopt plant-derived feeds such as soybean, wheat voluntarily; These plant materials to milk replacer, open foodstuff the pH value be that sour power all has different influences; This also is when feeding plant-derived milk replacer, and calf, lamb are slightly poorer than one of reason of newborn source property milk replacer to the utilization rate of nutriment, growth efficiency etc.Under China's production status, external knowhow be can use for reference and calf, lamb milk replacer feeding value improved with the acidifying means, reduce disease and take place, promote its healthy growth.And in the plant-derived milk replacer acidity regulator kind and the prescription do not appear in the newspapers as yet.Contemporary dairy products are fed to calf and lamb with the liquid mode, and it is convenient for the small-scale raiser to add acidity regulator with the liquid mode.
3. domestic related patent U.S. Patent No. situation
Research in China personnel aspect calf, lamb milk replacer application some patented technologies; Such as; The calf lamb milk replacer patent of at present having authorized has: ZL 02128844.5; CN 03132566.1 etc.; This research team is exactly wherein relatively more outstanding one, has patent of invention " a kind of calf lamb is used milk replacer " (ZL 02128844.5), " two stage calf milk substitutes " (ZL 200710097789.7) patent, " with glucose or the application of starch in replace of whey powder (lactose) in calf milk substitute " (ZL 200810097548.7).
This combined acidity conditioning agent and other acidity regulators, acidulant difference are:
(1) constituent and ratio.The organic acid that uses in the preparation of this combined acidity conditioning agent, the kind of inorganic acid and ratio are according to prescription uniform Design method, on the basis of test determination, screen.Wherein the kind of acid comprises formic acid, hydrochloric acid and citric acid, and its ratio is at formic acid 20%～60%, hydrochloric acid 30%～70%, and citric acid 1%～10%, the prescription summation reaches 100%.
(2) purposes and form.Because this combined acidity conditioning agent will be used in calf milk substitute or the lamb milk replacer specially, thus water-soluble to it, be prone in emulsion, add etc. the aspect require comparatively special.This patent product does not need complicated processing technology, can be prepared voluntarily by calf, lamb keeper, and join existing usefulness at present, and compound method is easy to learning and mastering, and addition manner is simple, especially is fit to middle-size and small-size plant, family use.
4. the technical support that gives of this research team
The inventor is engaged in the research of ruminant animal nutrition and forage science for a long time, presides over multinomial major research item, is especially doing a lot of work aspect the nutrition of cub physiology and in the development of feed, particularly calf, lamb milk replacer.Team Member of the present invention all possesses sturdy professional knowledge and rigorous scientific research attitude.Of the present inventionly declare the experiment work that comes from accumulation for a long time and carried out in recent years.Lab analysis and the animal experiment that are provided in the result of use of the present invention data from a series of rigorous design, implementation specification, analysis science.
[summary of the invention]
1. technical characterstic of the present invention: the present invention is directed to the problem that the actual and existing patented technology of production exists, screen reasonable, effective combined acidity conditioning agent, and confirm effectively to improve the growth of animal performance through animal experiment with the scientific experimentation method.Characteristics of the present invention are:
1.1 the pH value of calf milk substitute or lamb milk replacer emulsion is reduced to 5.0～5.5, be the best with 5.0.
1.2 the liquid combined acidity conditioning agent that uses in the calf lamb milk replacer is made up of following constituent and percent by volume thereof, wherein formic acid 20%～60%, hydrochloric acid 30%～70%, and citric acid 1%～10%, the summation of three kinds of acid reaches 100%.Optimum formula is formic acid 40.74%, hydrochloric acid 50.62%, citric acid 8.64%.
1.3 as long as formic acid, hydrochloric acid and the citric acid produced both at home and abroad reach food-grade or feed grade, all can be used as raw material of the present invention, be mixed with 10% solution according to w/v.When material effective component content and this patent mark inequality, can be through calculating adjustment raw material consumption to reach identical active constituent content.
2. the concrete compound method of combined acidity conditioning agent of the present invention is:
Earlier formic acid, hydrochloric acid and citric acid being mixed with w/v separately is that 10% the aqueous solution is subsequent use, before feed calf or the lamb, measures the volume of the required aqueous solution separately according to the ratio that prescription is formed at every turn, is liquid combined acidity conditioning agent after mixing.Join existing usefulness at present.
3. the method for using of combined acidity conditioning agent of the present invention
Earlier calf milk substitute or lamb milk replacer are mixed with emulsion according to product or the actual requirement of production; Again liquid combined acidity conditioning agent is added in the milk replacer emulsion; Stir, make the pH of milk replacer emulsion be reduced to 5.0～5.5, the best is can feed after 5.0 calf or lamb.
[specific embodiment]
Optimization of formulation in the instance 1 liquid combined acidity conditioning agent
Adopt the lab analysis means to carry out the screening of combined acidity conditioner formulations.
1. test material and method
1.1 test material
Selecting the pure formic acid of analysis, acetate, citric acid, fumaric acid, lactic acid, hydrochloric acid for use is test material.
20 compound acid of table 2 preparation are pressed in the preparation of composite acid-soluble liquid, and progressively dilute with SPSS, are mixed with 10%, 1.0%, 0.1%, 0.02% solution for standby respectively.
1.2 experimental design
" prescription uniform Design " method of employing as the best compatibility major ingredient of acidity regulator, is combined into 20 processing to 6 kinds of acid with formic acid, acetate, citric acid, fumaric acid, lactic acid, hydrochloric acid, and each handles 5 repetitions.Set up percentage and the regression equation between each index of each acid in prescription, try to achieve optimal solution, promptly obtain optimization formula through optimizing." uniform Design V5.0 software " (uniform Design branch of Chinese Mathematical Society makes, 2006) adopted in test, according to U in the uniform designs table
20 *(20
6) the constrained formulation design is arranged, arrange Uniform Design with 6 factors, the constraints of each acid in prescription is all minimum of a value 0, maximum 1.0.
1.3 test daily ration
Test uses milk replacer to be Institute of Feeds,China Academy of Agriculture Sciences's livestock nutrition research department patented product, and milk replacer emulsion compound method does, the hot water and the milk replacer dry powder that are cooled to 40～50 ℃ after usefulness is boiled brew by 7: 1 weight ratio, make it to become emulsion.
1.4 testing index and method
Testing index is according to (2007b) contained project is selected for Qin Shengtao etc., 2007a, and has carried out partly improvement.Specifically comprise:
The acidity of 1% acid solution is measured the pH value of 1% acid solution with acidometer.
The acidity regulator shock-absorbing capacity is the shock-absorbing capacity of acidity adjustment agent solution 1.: with the NaOH solution titration of 1% acid solution with 1mol/L, measure the pH value with acidometer while stirring.The molal quantity of the NaOH that recording solution pH value is consumed when changing an integer (Qin Shengtao etc., 2007a).2. the shock-absorbing capacity of acidity regulator in the milk replacer: with acidity regulator solution titration milk replacer emulsion, make its pH value reach 5.0 after, adopt 1. method to measure shock-absorbing capacity.Because the final application purpose of acidity regulator in this research is to reduce the pH value of calf milk substitute emulsion, therefore ad hoc this index of having counted.
The volume that reduces the required acid of milk replacer ph value of emulsion to 5.0 adds 10% acid solution in the milk replacer emulsion, measure ph value of emulsion while stirring, until reaching 5.0.The volume of 10% acid solution that is metered into.
External bacteriostasis rate Escherichia coli adopt the EMB solid medium to cultivate counting.With the Escherichia coli bacterial classification of preserving (available from China Veterinery Drug Inspection Office; Bacterial strain number is CVCC 222, and serotype 0141:K99 is from diarrhoea calf ight soil) choose single bacterium colony in fluid nutrient medium; In 37 ℃ of incubators, cultivating 18h, is 10 with this bacteria suspension by 10 times of serial dilutions
-1, 10
-2, 10
-3, 10
-4, 10
-5, 10
-6, 10
-7, 10
-8Concentration, promptly getting the 9mL SPSS, to add the 1mL bacteria suspension be 10
-1, and by that analogy.Choose 0.1mL bacterium liquid and put on the solid medium, push away even back and cultivate the 18h counting, calculate the bacterium colony number, be bacteria suspension concentration (Qin Shengtao etc., 2007b), subsequent use.Get the subsequent use bacterium liquid of 0.2mL and add respectively in the sterile test tube of acid solution that 1.8mL 0.02% is housed and SPSS control group, be 10
-1Solution is 10 by 10 times of serial dilutions with this solution successively
-2, 10
-3, 10
-4, 10
-5, 10
-6Concentration solution.From every test tube, draw 0.1mL and be applied on the solid medium, with the spreading rod coating evenly, put into 37 ℃ of constant incubators and cultivate 18h, the record clump count.Each concentration of each acid solution do 3 parallel, get its mean value.
External bacteriostasis rate (%)=(control group clump count-test group clump count)/control group clump count * 100
1.5 data statistic analysis
Use uniform Design V5.0 software (uniform Design branch of Chinese Mathematical Society) that a plurality of indexs are carried out stepwise regression analysis, ask comprehensive dependent variable optimal solution.
2. result and analysis
Be that each group difference is (P＜0.01) extremely significantly according to each item achievement data of 20 compound acid of prescription uniform Design form preparation in the table 1.
The measured value of the compound sour each item index of table 1
1) in the table, Y
1=external bacteriostasis rate; Y
2The pH value of=1% acid solution; Y
3=1% acid solution buffer capacity (1N NaOH volume); Y
4The volume of the acid that=reduction milk replacer pH value to 5.0 is required; Y
5=add acid back milk replacer buffer capacity (1N NaOH volume).
Table 2 combined acidity conditioner formulations optimal solution result of calculation
1) in the table, Y
1=external bacteriostasis rate; Y
2The pH value of=1% acid solution; Y
3=1% acid solution buffer capacity (1N NaOH volume); Y
4The volume of the acid that=reduction milk replacer pH value to 5.0 is required; Y
5=add acid back milk replacer buffer capacity (1N NaOH volume).
Use uniform Design 5.0 softwares that data are carried out stepwise regression analysis, with Y
1～Y
5(Y
1=external bacteriostasis rate; Y
2The pH value of=1% acid solution; Y
3=1% acid solution buffer capacity; Y
4The volume of the acid that=reduction milk replacer pH value to 5.0 is required; Y
5=add acid back milk replacer buffer capacity) and be dependent variable, calculate acidity adjustment agent prescription comprehensive optimal solution, its result sees table 2.The acidity regulator that in milk replacer, uses, under this experimental condition, its optimum formula is formic acid 40.74%, hydrochloric acid 50.62%, citric acid 8.64%.
The preparation and the calf rearing test effect of instance 2 liquid combined acidity conditioning agents
In milk replacer, add the effect of combined acidity conditioning agent through the calf rearing verification experimental verification.
1. test material and method
1.1 test material
Liquid combined acidity conditioning agent, formulated by Institute of Feeds,China Academy of Agriculture Sciences, its prescription is formic acid 40.74%, hydrochloric acid 50.62%, citric acid 8.64%.All test use acid dilutions before use are 10% solution.
1.2 experimental design
Be divided into control group and test group.The control group calf conventional milk replacer emulsion of feeding, its pH value is 6.2, adds the combined acidity conditioning agent in the test group milk replacer emulsion, makes its pH value be reduced to 5.0.6 repetitions are established in each processing, and each repeats 1 calf.
1.3 experimental animal and raising
The test calf is chosen from the subordinate of ternary group milk cattle cultivating field, is about 24 spontaneous labors, 1～3 tire, birth weight 40kg, the newborn Chinese He Sitan bull calf of 5～7 ages in days, after birth, separates with cow immediately.Use indoor online single hurdle (0.9m * 3.5m) raise hurdle of every calf.Write down feed intake, body weight, body chi, diarrhoea data such as a situation arises separately.Experimental period 56d.
1.4 test daily ration
The calf basal diet comprises milk replacer and opens foodstuff two parts.(8:30,18:00) the milk replacer emulsion of feeding at twice every day whole test phase, compound method do, brews with the weight ratio of milk replacer dry powder by 7: 1 with the hot water that is cooled to 40～50 ℃ after boiling, and makes it to become the emulsion calf of feeding, and the back of feeding replenishes drinks water.Milk replacer emulsion day scale of feeding is 10% of a calf body weight, and with the per two weeks adjustment of calf body weight gain once.Before feeding acidity regulator is added in the milk replacer emulsion, by its pH value of experimental design requirement adjustment at every turn.21d begins to train the calf foodstuff of searching for food out after on-test, and feed intake is supplied with the system of raising in the basic upper limit that satisfies the calf demand basically taked, and every calf supplementary feeding every day amount is: 21～28d, 150g; 29～35d, 300g; 36～42d, 500g; 43～56d, 600g.
The product of milk replacer as the research and development of Institute of Feeds,China Academy of Agriculture Sciences livestock nutrition research department used in test, opens the raw material composition of foodstuff and the nutrition content of milk replacer and sees table 3.Milk replacer and open and all do not add any medicated feed additive in the foodstuff.
The composition of table 3 basal diet and nutritional labeling (air dry matter basis)
1) is measured value.
2) open foodstuff and provide for every kilogram: Fe 9mg; Cu 12.5mg; Mn 103mg; Zn 100mg; Se 0.3mg; I 1.5mg; Co 0.5mg; VA 15 000IU; VD
35 000IU; VE 50mg.
1.5 testing index
1.5.1 growth performance
The body weight that per two weeks are measured calf writes down feed supply amount, feed surplus and stools scored every day.Calculate daily gain, diarrhea rate, daily ingestion amount, feed conversion rate.
1.5.2 vim and vigour index
After on-test the 0th, 14,42d raises back 2h morning, each processed group is chosen 3 calves blood samplings.Use vacuum vim and vigour pin by the about 3mL of jugular vein blood drawing earlier, put into 0～8 ℃ of vacuum flask behind the hand rubbing mixing immediately, in 1h, measure the vim and vigour index.
Vim and vigour index use RADIOMETER COPENHAGEN (thunder degree) ABL 5 type instruments are with determination of electrode and calculate pH value of blood, partial pressure of carbon dioxide (PCO
2), oxygen partial pressure (PO
2), oxygen saturation (SO
2), HCO
3 -Concentration ([HCO
3 -]), real surplus alkali number (ABE), total carbon dioxide volume (TCO
2), standard bicarbonate salinity (SBC) and standard residue alkali (SBE).
2. result of the test
2.1 growth performance
Respectively organize body weight, average daily gain, average daily feed intake, feed conversion rate and the diarrhea rate data of calf in the test and see table 4.
Compare with control group, the full phase average daily gain of test group calf increases, wherein two groups of significant differences of 14～28d (P＜0.05).And in each stage the average daily feed intake difference of calf neither significantly (P＞0.05) between two groups.
The feed conversion rate of two groups of calves significant difference (P＜0.05) occurs in 14～28d stage, and wherein test group is superior to control group, and other each stage differences are remarkable (P＞0.05) not.
After adding acidity regulator, the full phase diarrhea rate of calf decreases, and test group has reduced by 13.9% than control group, but two group differences not significantly (P＞0.05).
Add weightening finish, feed intake, feed conversion rate and the diarrhea rate of calf behind the acidity regulator in table 4 milk replacer
1)
A, b, cWith line data shoulder mark different lowercase person significant differences (P＜0.05).Shoulder is marked same letter or is not had shoulder marking-up mother person difference not remarkable (P＞0.05).
2) SEM is the maximum in the standard error of each processed group.
Add the influence of acidity regulator in table 5 milk replacer to calf blood vim and vigour index
1) SEM is the maximum in the standard error of each processed group.
2.2 vim and vigour index
Table 5 is the numerical value of calf blood vim and vigour index behind the milk replacer of feeding.
Whether add acidity regulator each item vim and vigour index of full phase of calf is not all made significant difference, but between different days, different effects is arranged, wherein be mainly 14d.Compare pH value, the SO of calf blood when feeding acidity regulator 14d with the calf of not adding the acidity regulator milk replacer of feeding
2Increase (P＜0.05) PCO
2Then reduce (P＜0.05).
3. conclusion
Under this experimental condition, to calf feed added the milk replacer of liquid combined acidity conditioning agent after:
Feed during the 14～28d of back, the calf daily gain is significantly improved; 14d after feeding, calf vim and vigour part index number is improved.
In general, the calf effect of this liquid combined acidity conditioning agent before for 28d is bigger.
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Claims (3)
1. the liquid combined acidity conditioning agent that uses in the calf lamb milk replacer; It is characterized in that being made up of following constituent and percent by volume thereof, wherein formic acid 20%～60%, hydrochloric acid 30%～70%; Citric acid 1%～10%, the summation of three kinds of acid are 100%.
2. the compound method of liquid combined acidity conditioning agent according to claim 1; It is characterized in that earlier it is that 10% the aqueous solution is subsequent use that formic acid, hydrochloric acid and citric acid are mixed with w/v separately; Feed before calf or the lamb at every turn; Ratio according to prescription is formed is measured the volume of the required aqueous solution separately, and three kinds of acid are mixed into liquid combined acidity conditioning agent, joins existing usefulness at present.
3. the method for using of liquid combined acidity conditioning agent according to claim 1; It is characterized in that earlier calf milk substitute or lamb milk replacer being mixed with emulsion; Again liquid combined acidity conditioning agent is added in the milk replacer emulsion; Stir to feed after making the pH of milk replacer emulsion be reduced to 5.0～5.5 lamb or calf.
Priority Applications (1)
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| CN104489278A (en) * | 2015-01-05 | 2015-04-08 | 贵州大学 | Extremely-low milk protein milk replacer for calves under over-early weaning and preparation method of extremely-low milk protein milk replacer |
| CN106472694A (en) * | 2015-08-26 | 2017-03-08 | 中创云牧科技咨询(北京)股份有限公司 | A kind of preparation method promoting calf appetite and the acidified powdered milk of cud growth |
| CN106472830A (en) * | 2015-08-26 | 2017-03-08 | 中创云牧科技咨询(北京)股份有限公司 | A kind of preparation of acidified powdered milk promoting calf cud to develop and application process |
| CN106472691A (en) * | 2015-08-26 | 2017-03-08 | 中创云牧科技咨询(北京)股份有限公司 | A kind of preparation of Compound-acid acidified powdered milk and application process |
| CN106561824A (en) * | 2015-10-08 | 2017-04-19 | 中创云牧(内蒙古)科技咨询有限公司 | Formula of acidified milk for calves and feeding method therefor |
| CN106614255A (en) * | 2015-10-30 | 2017-05-10 | 中创云牧科技咨询(北京)股份有限公司 | Method for producing little white lamb meat |
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| CN107125194A (en) * | 2016-02-29 | 2017-09-05 | 中创云牧科技咨询(北京)股份有限公司 | A kind of feeding method of lamb |
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| CN111109462A (en) * | 2020-01-03 | 2020-05-08 | 江苏奥迈生物科技有限公司 | Liquid acidity regulator for livestock and poultry production and preparation method thereof |
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| CN104489278A (en) * | 2015-01-05 | 2015-04-08 | 贵州大学 | Extremely-low milk protein milk replacer for calves under over-early weaning and preparation method of extremely-low milk protein milk replacer |
| CN106472694A (en) * | 2015-08-26 | 2017-03-08 | 中创云牧科技咨询(北京)股份有限公司 | A kind of preparation method promoting calf appetite and the acidified powdered milk of cud growth |
| CN106472830A (en) * | 2015-08-26 | 2017-03-08 | 中创云牧科技咨询(北京)股份有限公司 | A kind of preparation of acidified powdered milk promoting calf cud to develop and application process |
| CN106472691A (en) * | 2015-08-26 | 2017-03-08 | 中创云牧科技咨询(北京)股份有限公司 | A kind of preparation of Compound-acid acidified powdered milk and application process |
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| CN106614254A (en) * | 2015-10-30 | 2017-05-10 | 中创云牧科技咨询(北京)股份有限公司 | Production method for white veal |
| CN107125194A (en) * | 2016-02-29 | 2017-09-05 | 中创云牧科技咨询(北京)股份有限公司 | A kind of feeding method of lamb |
| CN107397055A (en) * | 2016-05-18 | 2017-11-28 | 中创云牧科技咨询(北京)股份有限公司 | One kind acidifying milk and preparation method thereof and application method |
| CN111109462A (en) * | 2020-01-03 | 2020-05-08 | 江苏奥迈生物科技有限公司 | Liquid acidity regulator for livestock and poultry production and preparation method thereof |
| CN118203071A (en) * | 2024-01-22 | 2024-06-18 | 江苏瑞牧生物科技有限公司 | Method for improving viscosity of whole wheat flour |
| CN118203071B (en) * | 2024-01-22 | 2024-09-24 | 江苏瑞牧生物科技有限公司 | Method for improving viscosity of whole wheat flour |
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