CN102302682A - Chinese medicinal preparation for treating intervertebral disc herniation and preparation method for Chinese medicinal preparation - Google Patents
Chinese medicinal preparation for treating intervertebral disc herniation and preparation method for Chinese medicinal preparation Download PDFInfo
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- CN102302682A CN102302682A CN201110259727A CN201110259727A CN102302682A CN 102302682 A CN102302682 A CN 102302682A CN 201110259727 A CN201110259727 A CN 201110259727A CN 201110259727 A CN201110259727 A CN 201110259727A CN 102302682 A CN102302682 A CN 102302682A
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Abstract
The invention relates to a Chinese medicine, in particular to a Chinese medicinal preparation for treating intervertebral disc herniation and a preparation method for the Chinese medicinal preparation. The Chinese medicinal preparation is prepared from the following raw materials in part by weight: 5 to 7 parts of Chinese taxillus twig, 4 to 6 parts of safflower, 4 to 6 parts of peach seed, 5 to 7 parts of red paeony root, 5 to 7 parts of east Asian tree fem rhizome, 0.8 to 1.4 parts of frankincense, 2 to 2.8 parts of myrrh, 2 to 2.8 parts of liquoric root, 5 to 7 parts of cortex eucommiae, 5 to 7 parts of rhizoma corydalis, 4 to 5.6 parts of ligusticum wallichii, 6.5 to 7.9 parts of angelica sinensis, 5 to 7 parts of achyranthes bidentata, 3.5 to 4.5 parts of ground beetle, 2 to 2.8 parts of gastrodia elata, 2 to 2.8 parts of common vladimiria root, 5 to 7 parts of fructus corni, 3 to 5 parts of manchurian wildginger, 0.2 to 0.6 part of nux vomica and 1.1 to 2.1 parts of notoginseng root. The raw materials are used together to achieve the effects of improving micro circulation, expanding capillary, dispelling nerve root inflammation and edema, resisting inflammation and easing pain, inhibiting exuding of inflammation, improving immunoregulation, relieving and removing immunization inflammation, so the Chinese medicinal preparation has good curative effect on intervertebral disc herniation.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine preparation of treating prolapse of lumbar intervertebral disc and preparation method thereof.
Background technology
Prolapse of lumbar intervertebral disc is clinically one of comparatively common waist illness, is commonly encountered diseases, the frequently-occurring disease of orthopedics department.Lumbar intervertebral disc is present between each vertebral body of lumbar vertebra, is the ingredient of joint of lumbar vertebra, and lumbar vertebra is played support, connection and buffered effect, and its shape resembles an abacus bead that flattens, and is made up of vertebral pulp, cartilaginous lamina, fibrous ring three parts.Protruding or fracture after causing fibrous ring owing to reasons such as wound, regressions, vertebral pulp is deviate from, and just is called prolapse of lumbar intervertebral disc.Because spinal cord is by the rear process of intercalated disc, when outstanding intercalated disc compressing spinal nerves or cauda equina nerve cause lumbago and skelalgia or gatism even cause paralysis, just be called prolapse of lumbar intervertebral disc.
Its Therapeutic Method mainly comprises Drug therapy, magnetic therapy and operative treatment, wherein:
1, Drug therapy comprises nonsteroidal analgesic such as indometacin, ibuprofen etc., and analgesic effect is strong, and antiinflammatory and anti rheumatism action are also stronger.But general anti-inflammatory analgesic class medicine can not be taken the long period, especially more will note taboo for suffering from liver/nephropathy, hypertension, diabetics simultaneously, in order to avoid cause new uncomfortable disease.General anti-inflammatory analgesic class medicine needs one after each meal, patient more will note medicine contraindication.Medicine absorbs, digests, decomposes through the intestines and stomach, at last through blood circulation, just can give the part with the medicine input; Whole process need passes through layer by layer, and barrier could arrive lesions position; Right drug effect remains little, so effect very slowly and poor efficiency, and these methods of clinical practice can only the alleviating pain symptom; Functional rehabilitation can't reverse, and the sclerotin reparation is not known where to begin especially.And oral medicine is very big to liver, kidney, gastrointestinal damage.
2, magnetic therapy promptly is with the method for the action of a magnetic field in the human disease treatment.The distribution of influence of magnetic field body current, the motion of charged microgranule, the permeability of film system etc. change histiocytic physiology, biochemical process, produce analgesia, detumescence, promote effects such as blood and lymph circulation.But at present also under study for action, its clinical treatment is slow, and effect is not good enough.
3, operative treatment comprises the micro-endoscopic discectomy Minimally Invasive Surgery, and nucleus pulposus is cut the suction art.Operation is not that each patient is fit to, and operation is big for the human body wound, recovers slowly.
Summary of the invention
In order to address the above problem, the object of the present invention is to provide a kind of for Chinese medicine preparation of treating the prolapse of lumbar intervertebral disc better efficacy and having no side effect and preparation method thereof.
For realizing foregoing invention first purpose, technical scheme that the present invention adopts is following:
A kind of Chinese medicine preparation of treating prolapse of lumbar intervertebral disc, it is the medicament of being processed by the raw material of following ratio of weight and number:
Herba Taxilli 5-7 part, Flos Carthami 4-6 part, Semen Persicae 4-6 part, Radix Paeoniae Rubra 5-7 part, Rhizoma Cibotii 5-7 part, Olibanum 0.8-1.4 part, Myrrha 2-2.8 part, Radix Glycyrrhizae 2-2.8 part, burnt Cortex Eucommiae 5-7 part, Rhizoma Corydalis 5-7 part, Rhizoma Chuanxiong 4-5.6 part, Radix Angelicae Sinensis 6.5-7.9 part, Radix Achyranthis Bidentatae 5-7 part, eupolyphaga 3.5-4.5 part, Rhizoma Gastrodiae 2-2.8 part, Radix Aucklandiae 2-2.8 part, Fructus Corni 5-7 part, Herba Asari 3-5 part, Semen Strychni 0.2-0.6 part, Radix Notoginseng 1.1-2.1 part.
As optimal proportion prescription of the present invention, its raw materials in part by weight ratio is:
6 parts of Herba Taxillis, 4.8 parts on Flos Carthami, 4.8 parts in Semen Persicae, 6 parts of Radix Paeoniae Rubra, 6 parts of Rhizoma Cibotii, 1.2 parts of Olibanums, 2.4 parts of Myrrhas, 2.4 parts in Radix Glycyrrhizae, 6 parts of the burnt Cortexs Eucommiae, 6 parts of Rhizoma Corydalis, 4.8 parts of Rhizoma Chuanxiongs, 7.2 parts of Radix Angelicae Sinensis, 6 parts of Radix Achyranthis Bidentataes, 4 parts of eupolyphaga, 2.4 parts in Rhizoma Gastrodiae, 2.4 parts of the Radix Aucklandiae, 6 parts of Fructus Corni, 4 parts of Herba Asaris, 0.4 part of Semen Strychni, 1.6 parts of Radix Notoginseng.
Optional, the dosage form of said Chinese medicine preparation is powder, tablet, pill, granule or capsule.
For realizing foregoing invention second purpose, technical scheme that the present invention adopts is following:
The method for preparing of said Chinese medicine preparation may further comprise the steps:
(1), with Rhizoma Chuanxiong, Radix Angelicae Sinensis, the Radix Aucklandiae, Herba Asari, it is subsequent use to extract volatile oil;
(2), with the medicinal residues in the step (1) and Herba Taxilli, Semen Persicae, Flos Carthami, Rhizoma Cibotii, the burnt Cortex Eucommiae, Radix Glycyrrhizae Preparata decocte with water secondary, each 2 hours, collecting decoction filtered, it is 1.10～1.20 clear paste that filtrating is concentrated into relative density;
(3), all the other medical material Rhizoma Corydalis, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Olibanum, Myrrha, eupolyphaga, Rhizoma Gastrodiae, Fructus Corni, Radix Notoginseng, Semen Strychni Pulveratum are broken into fine powder, all through mixing behind 100 mesh sieves;
(4), get the medicated powder in the step (3), add the volatile oil of preparation in the step (1), with pill after the clear paste of preparation in the step (2) mixes, 50-55 ℃ of drying, polishing promptly gets.
In the present invention's prescription, the burnt Cortex Eucommiae, liver and kidney tonifying, bone and muscle strengthening; Fructus Corni also is the nourishing liver and kidney tonifying; Radix Achyranthis Bidentatae, Herba Taxilli, Rhizoma Cibotii, but invigorating the liver and kidney, strong waist knee joint, remove rheumatism, the meridian dredging, and the Radix Achyranthis Bidentatae diuretic of holding concurrently is wet; Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Olibanum, Myrrha, Rhizoma Corydalis, eupolyphaga, Flos Carthami, Semen Persicae, pseudo-ginseng blood-circulation-invigovating blood stasis dispelling are led to stagnant, the promoting the circulation of QI for relieving swelling pain relieving, and Radix Angelicae Sinensis has the merit of benefiting blood and regulating blood circulation concurrently, and Rhizoma Chuanxiong has the effect of dispeiling pathogenic wind and removing dampness concurrently; The pain relieving of holding concurrently of the gas of the capable the whole body of the Radix Aucklandiae; The Radix Glycyrrhizae relieving spasm to stop pain, benefiting vital QI and blood.Full side plays blood circulation promoting and blood stasis dispelling altogether, reducing swelling and alleviating pain, and waist is strengthened in the kidney invigorating, the merit of promoting the flow of QI in the collateral by warming the meridian.
Microcirculation improvement is played in these medicine combineds effect, and the expansion blood capillary is eliminated nerve root inflammation, edema; Anti-inflammatory and antalgic, the oozing out of inflammation-inhibiting; Enhancing human body immunity is regulated, and alleviates and eliminate the effect of immune inflammation, so we have curative effect preferably to prolapse of lumbar intervertebral disc.
The specific embodiment
To combine the practical implementation method to specify the present invention below, be used for explaining the present invention in schematic enforcement of the present invention and explanation, but not as to qualification of the present invention.
Embodiment 1:
A kind of Chinese medicine preparation of treating prolapse of lumbar intervertebral disc, it is the medicament of being processed by the raw material of following ratio of weight and number:
5 parts of Herba Taxillis, 4 parts on Flos Carthami, 4 parts in Semen Persicae, 5 parts of Radix Paeoniae Rubra, 5 parts of Rhizoma Cibotii, 0.8 part of Olibanum, 2 parts of Myrrhas, 2 parts in Radix Glycyrrhizae, 5 parts of the burnt Cortexs Eucommiae, 5 parts of Rhizoma Corydalis, 4 parts of Rhizoma Chuanxiongs, 6.5 parts of Radix Angelicae Sinensis, 5 parts of Radix Achyranthis Bidentataes, 3.5 parts of eupolyphaga, 2 parts in Rhizoma Gastrodiae, 2 parts of the Radix Aucklandiae, 5 parts of Fructus Corni, 3 parts of Herba Asaris, 0.2 part of Semen Strychni, 1.1 parts of Radix Notoginseng.
Its preparation method is following:
(1), with Rhizoma Chuanxiong, Radix Angelicae Sinensis, the Radix Aucklandiae, Herba Asari, it is subsequent use to extract volatile oil; Rhizoma Chuanxiong, Radix Angelicae Sinensis, the Radix Aucklandiae, Herba Asari contain volatile ingredient because of it, adopt steam distillation to extract volatile ingredient, and medicinal residues are again with other medicine decocte with water that need decoct, to carry most effective ingredient.
(2), with the medicinal residues in the step (1) and Herba Taxilli, Semen Persicae, Flos Carthami, Rhizoma Cibotii, the burnt Cortex Eucommiae, Radix Glycyrrhizae Preparata decocte with water secondary, each 2 hours, collecting decoction filtered, it is 1.10～1.20 clear paste that filtrating is concentrated into relative density; Medicines such as Herba Taxilli, Semen Persicae, Flos Carthami, Rhizoma Cibotii, the burnt Cortex Eucommiae can be known from documents and materials, contain starch, materials such as water-soluble phenolic acids, water solubles all, available water boiling and extraction.Doubly amount, extraction time, extraction time are investigated to solvent through experimentation; Selection with solvent doubly amount, extraction time, extraction time as the investigation factor; Content with contained pinoresinol diglucoside in the dried cream amount of fried thing and the Cortex Eucommiae serves as to investigate index, the optimal processing parameter that preferred water is extracted.Can know that by result of the test the water extraction optimised process is the decocte with water secondary, each 2 hours; With above aqueous extract take concentrating under reduced pressure (70～80 ℃ ,-0.08MPa), being concentrated into relative density is 1.10～1.20 (60 ℃), because of concentrating under reduced pressure efficient is high, loss of effective components is less, so the employing concentrating under reduced pressure.
(3), all the other medical material Rhizoma Corydalis, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Olibanum, Myrrha, eupolyphaga, Rhizoma Gastrodiae, Fructus Corni, Radix Notoginseng, Semen Strychni Pulveratum are broken into fine powder, all through mixing behind 100 mesh sieves; Fructus Corni contains glycoside, organic acid, 23 kinds of mineral elements such as potassium, calcium, magnesium, silicon, phosphorus and vitamin A; Vitamin B2, multiple composition such as vitamin C, Olibanum, the resinous composition of Myrrha; Eupolyphaga Seu Steleophaga is an animal medicinal material, and Rhizoma Gastrodiae, Radix Notoginseng are valuable fines medicine, and the Semen Strychni consumption is little etc.; In conjunction with the preparation technology of physicochemical property, modern pharmacological research and the concentrated pill of every flavor medical material, thus medical materials such as Rhizoma Corydalis, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Olibanum, Myrrha, Eupolyphaga Seu Steleophaga, Rhizoma Gastrodiae, Fructus Corni, Radix Notoginseng, Semen Strychni are pulverized, according to version " regulation of Chinese pharmacopoeia in 2010; The fineness of powder of pill generally should be fine powder; Promptly sieve (100 order) through No. six, thus above medicine is pulverized, and subsequent use through 100 mesh sieves.
(4), get the medicated powder in the step (3), add the volatile oil of preparation in the step (1), with pill after the clear paste of preparation in the step (2) mixes, 50-55 ℃ of drying, polishing promptly gets.
Embodiment 2:
The different ratio prescriptions that only are its raw material of present embodiment and embodiment 1, its raw materials in part by weight ratio is:
7 parts of Herba Taxillis, 6 parts on Flos Carthami, 6 parts in Semen Persicae, 7 parts of Radix Paeoniae Rubra, 7 parts of Rhizoma Cibotii, 1.4 parts of Olibanums, 2.8 parts of Myrrhas, 2.8 parts in Radix Glycyrrhizae, 7 parts of the burnt Cortexs Eucommiae, 7 parts of Rhizoma Corydalis, 5.6 parts of Rhizoma Chuanxiongs, 7.9 parts of Radix Angelicae Sinensis, 7 parts of Radix Achyranthis Bidentataes, 4.5 parts of eupolyphaga, 2.8 parts in Rhizoma Gastrodiae, 2.8 parts of the Radix Aucklandiae, 7 parts of Fructus Corni, 5 parts of Herba Asaris, 0.6 part of Semen Strychni, 2.1 parts of Radix Notoginseng.
Embodiment 3:
The different ratio prescriptions that only are its raw material of present embodiment and embodiment 1, its raw materials in part by weight ratio is:
6 parts of Herba Taxillis, 4.8 parts on Flos Carthami, 4.8 parts in Semen Persicae, 6 parts of Radix Paeoniae Rubra, 6 parts of Rhizoma Cibotii, 1.2 parts of Olibanums, 2.4 parts of Myrrhas, 2.4 parts in Radix Glycyrrhizae, 6 parts of the burnt Cortexs Eucommiae, 6 parts of Rhizoma Corydalis, 4.8 parts of Rhizoma Chuanxiongs, 7.2 parts of Radix Angelicae Sinensis, 6 parts of Radix Achyranthis Bidentataes, 4 parts of eupolyphaga, 2.4 parts in Rhizoma Gastrodiae, 2.4 parts of the Radix Aucklandiae, 6 parts of Fructus Corni, 4 parts of Herba Asaris, 0.4 part of Semen Strychni, 1.6 parts of Radix Notoginseng.
More than the technical scheme that the embodiment of the invention provided has been carried out detailed introduction; Used concrete example among this paper the principle and the embodiment of the embodiment of the invention are set forth, the explanation of above embodiment only is applicable to the principle that helps to understand the embodiment of the invention; Simultaneously, for one of ordinary skill in the art, according to the embodiment of the invention, the part that on the specific embodiment and range of application, all can change, in sum, this description should not be construed as limitation of the present invention.
Claims (4)
1. a Chinese medicine preparation of treating prolapse of lumbar intervertebral disc is characterized in that, it is the medicament of being processed by the raw material of following ratio of weight and number:
Herba Taxilli 5-7 part, Flos Carthami 4-6 part, Semen Persicae 4-6 part, Radix Paeoniae Rubra 5-7 part, Rhizoma Cibotii 5-7 part, Olibanum 0.8-1.4 part, Myrrha 2-2.8 part, Radix Glycyrrhizae 2-2.8 part, burnt Cortex Eucommiae 5-7 part, Rhizoma Corydalis 5-7 part, Rhizoma Chuanxiong 4-5.6 part, Radix Angelicae Sinensis 6.5-7.9 part, Radix Achyranthis Bidentatae 5-7 part, eupolyphaga 3.5-4.5 part, Rhizoma Gastrodiae 2-2.8 part, Radix Aucklandiae 2-2.8 part, Fructus Corni 5-7 part, Herba Asari 3-5 part, Semen Strychni 0.2-0.6 part, Radix Notoginseng 1.1-2.1 part.
2. the Chinese medicine preparation of treatment prolapse of lumbar intervertebral disc according to claim 1 is characterized in that, said raw material weight umber ratio is:
6 parts of Herba Taxillis, 4.8 parts on Flos Carthami, 4.8 parts in Semen Persicae, 6 parts of Radix Paeoniae Rubra, 6 parts of Rhizoma Cibotii, 1.2 parts of Olibanums, 2.4 parts of Myrrhas, 2.4 parts in Radix Glycyrrhizae, 6 parts of the burnt Cortexs Eucommiae, 6 parts of Rhizoma Corydalis, 4.8 parts of Rhizoma Chuanxiongs, 7.2 parts of Radix Angelicae Sinensis, 6 parts of Radix Achyranthis Bidentataes, 4 parts of eupolyphaga, 2.4 parts in Rhizoma Gastrodiae, 2.4 parts of the Radix Aucklandiae, 6 parts of Fructus Corni, 4 parts of Herba Asaris, 0.4 part of Semen Strychni, 1.6 parts of Radix Notoginseng.
3. according to the Chinese medicine preparation of treatment prolapse of lumbar intervertebral disc according to claim 1, it is characterized in that:
The dosage form of said Chinese medicine preparation is powder, tablet, pill, granule or capsule.
4. the method for preparing of the said Chinese medicine preparation of claim 1 is characterized in that, may further comprise the steps:
(1), with Rhizoma Chuanxiong, Radix Angelicae Sinensis, the Radix Aucklandiae, Herba Asari, it is subsequent use to extract volatile oil;
(2), with the medicinal residues in the step (1) and Herba Taxilli, Semen Persicae, Flos Carthami, Rhizoma Cibotii, the burnt Cortex Eucommiae, Radix Glycyrrhizae Preparata decocte with water secondary, each 2 hours, collecting decoction filtered, it is 1.10～1.20 clear paste that filtrating is concentrated into relative density;
(3), all the other medical material Rhizoma Corydalis, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Olibanum, Myrrha, eupolyphaga, Rhizoma Gastrodiae, Fructus Corni, Radix Notoginseng, Semen Strychni Pulveratum are broken into fine powder, all through mixing behind 100 mesh sieves;
(4), get the medicated powder in the step (3), add the volatile oil of preparation in the step (1), with pill after the clear paste of preparation in the step (2) mixes, 50-55 ℃ of drying, polishing promptly gets.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106237185A (en) * | 2016-08-16 | 2016-12-21 | 李向松 | A kind of Chinese medicine treating prolapse of lumbar intervertebral disc |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100546600C (en) * | 2007-08-22 | 2009-10-07 | 丁艳玲 | A kind of Chinese medicine composition of orally taken for curing prolapse of lumbar intervertebral disc |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100546600C (en) * | 2007-08-22 | 2009-10-07 | 丁艳玲 | A kind of Chinese medicine composition of orally taken for curing prolapse of lumbar intervertebral disc |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106237185A (en) * | 2016-08-16 | 2016-12-21 | 李向松 | A kind of Chinese medicine treating prolapse of lumbar intervertebral disc |
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Application publication date: 20120104 |