CN102271715A - 对比剂组合物 - Google Patents
对比剂组合物 Download PDFInfo
- Publication number
- CN102271715A CN102271715A CN2010800044194A CN201080004419A CN102271715A CN 102271715 A CN102271715 A CN 102271715A CN 2010800044194 A CN2010800044194 A CN 2010800044194A CN 201080004419 A CN201080004419 A CN 201080004419A CN 102271715 A CN102271715 A CN 102271715A
- Authority
- CN
- China
- Prior art keywords
- bis
- alkyl
- conh
- composition
- choh
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- PCOGFUUOQLBHCL-UHFFFAOYSA-N OCCNC(c(c(I)c(c(I)c1C(NCC(CO)O)=O)N(CC(CC(CN(C=O)c(c(I)c(C(NCC(CO)O)=O)c(I)c2C(NCCO)=O)c2I)O)O)C=O)c1I)=O Chemical compound OCCNC(c(c(I)c(c(I)c1C(NCC(CO)O)=O)N(CC(CC(CN(C=O)c(c(I)c(C(NCC(CO)O)=O)c(I)c2C(NCCO)=O)c2I)O)O)C=O)c1I)=O PCOGFUUOQLBHCL-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0438—Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09150292 | 2009-01-09 | ||
| EP09150292.2 | 2009-01-09 | ||
| PCT/EP2010/050118 WO2010079201A1 (en) | 2009-01-09 | 2010-01-08 | Contrast media compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102271715A true CN102271715A (zh) | 2011-12-07 |
Family
ID=41650510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010800044194A Pending CN102271715A (zh) | 2009-01-09 | 2010-01-08 | 对比剂组合物 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20110256068A1 (https=) |
| EP (1) | EP2385845A1 (https=) |
| JP (1) | JP2012514622A (https=) |
| CN (1) | CN102271715A (https=) |
| WO (1) | WO2010079201A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104136045A (zh) * | 2011-12-21 | 2014-11-05 | 通用电气医疗集团股份有限公司 | X-射线诊断用组合物的稳定化 |
| CN119528755A (zh) * | 2024-11-21 | 2025-02-28 | 江西司太立制药有限公司 | 一种碘佛醇杂质及其制备方法 |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2566281C2 (ru) | 2010-07-12 | 2015-10-20 | ДжиИ Хелткер АС | Рентгеновская визуализация при низких концентрациях контрастного агента и/или низкой дозе излучения |
| WO2013041593A1 (en) | 2011-09-21 | 2013-03-28 | Ge Healthcare As | Packaging of contrast media |
| CN104114190A (zh) * | 2012-01-11 | 2014-10-22 | 通用电气医疗集团股份有限公司 | 具有低碘浓度的x-射线成像造影介质和x-射线成像方法 |
| US9355083B1 (en) * | 2015-02-06 | 2016-05-31 | Atlassian Pty Ltd | Systems and methods for generating an edit script |
| KR102447777B1 (ko) * | 2020-06-05 | 2022-09-28 | 서울대학교산학협력단 | 신규 폴리옥살레이트 유도체, 및 이를 포함하는 조영제 |
| CN113387832A (zh) * | 2021-05-25 | 2021-09-14 | 成都丽璟科技有限公司 | 一种高安全性的泛影酸衍生物造影剂及其制备方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1100329A (zh) * | 1992-12-24 | 1995-03-22 | 伯拉考公司 | 具有放射诊断用途的含有用途作x-射线对比介质的碘化芳香化合物的可注射含水配方 |
| WO1997000240A1 (en) * | 1995-06-16 | 1997-01-03 | Biophysica Foundation | Formyl derivatives as nonionic contrast media |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH608189A5 (https=) | 1974-12-13 | 1978-12-29 | Savac Ag | |
| GB1548594A (en) | 1976-06-11 | 1979-07-18 | Nyegaard & Co As | Triiodoisophthalic acid amides |
| DE2909439A1 (de) | 1979-03-08 | 1980-09-18 | Schering Ag | Neue nichtionische roentgenkontrastmittel |
| IT1193211B (it) | 1979-08-09 | 1988-06-15 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono |
| US4341756A (en) | 1980-01-31 | 1982-07-27 | The Regents Of The University Of California | Novel amino-dioxepane intermediates for the synthesis of new non-ionic contrast media |
| DK160868C (da) * | 1982-11-08 | 1991-10-14 | Nyegaard & Co As | Trijodfenylderivater, fremgangsmaader til fremstilling deraf og radiologisk praeparat indeholdende dem |
| JPH0813794B2 (ja) | 1985-08-09 | 1996-02-14 | クツク イマジング,インコ−ポレイテイド | イオン性コントラスト媒体からの非イオン性ポリオ−ルコントラスト媒体 |
| US5035877A (en) | 1985-08-09 | 1991-07-30 | Cook Imaging Corporation | Non-ionic contrast media from ionic contrast media |
| US5043152A (en) | 1988-06-02 | 1991-08-27 | Guerbet S.A. | Novel iodinated non-ionic triiodobenzene compounds and contrast media containing them |
| FR2634571B1 (fr) | 1988-07-19 | 1990-10-19 | Kodak Pathe | Procede d'organisation et de lecture d'un support magnetique et support en faisant application |
| GB9020091D0 (en) | 1990-09-14 | 1990-10-24 | Nycomed As | Contrast media |
| DE69524088T2 (de) | 1994-06-21 | 2002-08-29 | Mallinckrodt, Inc. | Verbesserte synthese von ioversol unter verwendung einer mit phosphorsäure modifizierten koaddition |
| GB9710726D0 (en) | 1997-05-23 | 1997-07-16 | Nycomed Imaging As | Compound |
| IT1319670B1 (it) | 2000-12-01 | 2003-10-23 | Bracco Spa | Processo per la preparazione di 5-ammino-n,n'-bis(2-idrossi-1-(idrossimetil)etil))-1,3-benzendicarbossammide (i) e 5-ammino-n,n'- |
| ATE529135T1 (de) * | 2004-03-11 | 2011-11-15 | Mallinckrodt Llc | Röntgenkontrastformulierung mit einem gemisch aus einem jodierten monomer und dimer |
| EP2178568B1 (en) * | 2007-07-12 | 2014-07-02 | Ge Healthcare As | Contrast agents |
| JP2011504939A (ja) * | 2007-11-07 | 2011-02-17 | ジーイー・ヘルスケア・アクスイェ・セルスカプ | 造影剤 |
-
2010
- 2010-01-08 CN CN2010800044194A patent/CN102271715A/zh active Pending
- 2010-01-08 US US13/142,309 patent/US20110256068A1/en not_active Abandoned
- 2010-01-08 EP EP10700010A patent/EP2385845A1/en not_active Withdrawn
- 2010-01-08 WO PCT/EP2010/050118 patent/WO2010079201A1/en not_active Ceased
- 2010-01-08 JP JP2011544864A patent/JP2012514622A/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1100329A (zh) * | 1992-12-24 | 1995-03-22 | 伯拉考公司 | 具有放射诊断用途的含有用途作x-射线对比介质的碘化芳香化合物的可注射含水配方 |
| WO1997000240A1 (en) * | 1995-06-16 | 1997-01-03 | Biophysica Foundation | Formyl derivatives as nonionic contrast media |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104136045A (zh) * | 2011-12-21 | 2014-11-05 | 通用电气医疗集团股份有限公司 | X-射线诊断用组合物的稳定化 |
| CN119528755A (zh) * | 2024-11-21 | 2025-02-28 | 江西司太立制药有限公司 | 一种碘佛醇杂质及其制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010079201A1 (en) | 2010-07-15 |
| JP2012514622A (ja) | 2012-06-28 |
| US20110256068A1 (en) | 2011-10-20 |
| EP2385845A1 (en) | 2011-11-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20111207 |