CN102247570B - Traditional Chinese medicine composition for treating cow ketosis - Google Patents

Traditional Chinese medicine composition for treating cow ketosis Download PDF

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Publication number
CN102247570B
CN102247570B CN2011102451149A CN201110245114A CN102247570B CN 102247570 B CN102247570 B CN 102247570B CN 2011102451149 A CN2011102451149 A CN 2011102451149A CN 201110245114 A CN201110245114 A CN 201110245114A CN 102247570 B CN102247570 B CN 102247570B
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parts
radix
chinese medicine
medicine composition
ketosis
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CN2011102451149A
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CN102247570A (en
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刘志辉
裴毅
王洪杰
苏永鹏
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Great Biology Pharmaceutical Tianjin Co Ltd
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Great Biology Pharmaceutical Tianjin Co Ltd
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Abstract

The invention relates to a traditional Chinese medicine composition for treating cow ketosis. The traditional Chinese medicine composition is prepared from the following ingredients in parts by weight: 75-85 parts of radix codonopsitis, 75-85 parts of rhizoma atractylodis, 55-65 parts of radix astragali, 55-65 parts of honeysuckle, 95-105 parts of ordate houttuynia, 45-55 parts of tuckahoe, 55-65 parts of angelica, 45-55 parts of motherwort, 35-45 parts of hemlock parsley, 55-65 parts of red paeonia, 55-65 parts of prepared rehmannia root, 75-85 parts of fructus amomi, 35-45 parts of jujube kernel, 35-45 parts of poria with hostwood, 25-35 parts of milkwort, 45-55 parts of fried fennel, 45-55 parts of costus root, 95-105 parts of medicated leaven, 45-55 parts of Atractylis ovata, 55-65 parts of Magnolia officinalis, 45-55 parts of bitter orange and 45-55 parts of licorice. The combination and preparation method of the traditional Chinese medicine composition provided by the invention are simple, and the traditional Chinese medicine composition has low cost and is safe and reliable; after the traditional Chinese medicine composition is administered, the symptoms of the cow suffering from ketosis is rapidly alleviated, the cow rapidly recovers, and the curative effect is obvious; and 58 cases of the cows suffering from ketosis are treated with the traditional Chinese medicine, and the curative rate reaches 86%.

Description

A kind of Chinese medicine composition of treating Ketosis
Technical field
The invention belongs to field of veterinary, especially a kind of Chinese medicine composition of treating Ketosis.
Background technology
Ketoacidosis is a milk bovine lactation modal metabolic disease of first month.
Ketosis etiology and pathogenesis be mainly:
1. expendable, hungry sexual factor
The main cause supply of forage is less, and low quality is single, and daily ration is under low albumen, the low-energy level, causes female animal can not absorb necessary nutrient substance;
2. spontaneous ketoacidosis
Under the condition of normally feeding, daily ration is under the condition of high-energy, high protein for a long time, causes high yield cow generation ketoacidosis.Be common in the high yield cow in 1~8 week of branch puerperium.Its morbidity is relevant with body digestion and metabolism malfunction, makes the competent carbohydrate of absorption can not change into due to the glucose;
3. Secondary cases factor
Milch cow is because forestomach atony, ruminal tympany, traumatic reticulitis, abomasum displacement, gastrointestinal, metritis, mastitis and other puerperal diseases; Often cause cow loss of appetite or useless exhausted; Can not take in enough food, body can not get due to the necessary nutrition;
4. food property or give birth to the ketone sexual factor
Ensilage and Radix Glycyrrhizae are the common feedstuffses of milch cow; Radix Glycyrrhizae contains ketogenic substance (butanoic acid) and lacks than the ensilage amount; Be higher than other ensilage and contain ketogenic substance by the ensilage that succulent fodder is processed, acetic acid content is too high in feedstuff, after absorbing, can change into beta-hydroxybutyric acid; Under the effect of beta-hydroxybutyric acid deoxygenase, be transformed into acetoacetic acid, can be changed into acetone after the acetoacetic acid decarboxylation.Therefore, cause milch cow generation ketoacidosis.
The clinical symptoms of Ketosis mainly shows as:
1. digestion type
Sick loss of appetite just, milk production descends, the refusing to eat concentrate, a small amount of Radix Glycyrrhizae of searching for food, appetite is useless exhausted then, different food, happiness drink sewage, urine is licked food dirt or earth, ruminates unable; Cud relaxes, and it is faint to wriggle; Feces is done and hard, and amount is few; Have with bloat, body weight obviously alleviates, skin elasticity reduces, spirit is depressed, bradykinesia is reluctant to walk about.Temperature pulse respiration is normal; Prolong with the course of disease, body temperature descends, and heart beating increases number, muffled heart sounds, and first, second hear sounds boundary line is unclear, thready pulse and faint.Serious symptom trouble poultry panhidrosis is spilt body like water, and hypourocrinia is, and special acetone abnormal smells from the patient is steeped, has in faint yellow, easy formation, and light disease person breast is measured and is persistence decline; Serious symptom person, the breast amount die-offs suddenly or agalactia, and special acetone abnormal smells from the patient (Fructus Mali pumilae flavor) is arranged.Once after the decline of breast amount, though warp is cured, how the breast amount can not return to the preceding level of disease fully.
2. nervous system type
Break out, do not recognize its groove, turn-take, sight is glared at, push way by shoving or bumping, and extremity fork or mutual the intersection, astasia, whole body is nervous, and musculi colli is tetanic, and is excited uneasy, and the act tail is bolted, and sky is chewed and is ground one's teeth in sleep, and sialorrhea is licked food skin, roars, and trembles.The nervous symptoms outbreak persistent period is shorter, and general 1~2 hour, but still had rebound phenomenon once more in 8~12 hours.The cattle that has is reluctant to walk about, and is slow-witted upright, the big-eared ear of bowing, and catacleisis, like sleeping appearance, external reaction is indifferent, is depressed shape.
At present, aspect treatment, clinical ketoacidosis often adopts glucose therapy, alternative medicine and hormonotherapy, and the constitutional ketoacidosis is had good effect, but under the situation that fatty liver takes place, the effect of these methods obviously descends.Curative effect is not comprehensive again for simple use hormone or additional glycogen or additional vector element, can not treat ketoacidosis on the whole, and therapeutic effect is not good.
Through retrieval, do not find the patent documentation relevant as yet with the present invention.
Summary of the invention
The objective of the invention is to overcome the deficiency of prior art, the Chinese medicine composition of simple, evident in efficacy, the safe and reliable treatment Ketosis of a kind of manufacture method is provided.
The present invention realizes that the technical scheme of purpose is:
A kind of Chinese medicine composition of treating Ketosis, it constitutes component and parts by weight are:
Radix Codonopsis 75-85 part, Rhizoma Atractylodis 75-85 part, Radix Astragali 55-65 part, Flos Lonicerae 55-65 part, Herba Houttuyniae 95-105 part, Poria 45-55 part, Radix Angelicae Sinensis 55-65 part, Herba Leonuri 45-55 part, Rhizoma Chuanxiong 35-45 part, Radix Paeoniae Rubra 55-65 part, Radix Rehmanniae Preparata 55-65 part, Fructus Amomi 75-85 part, Semen Ziziphi Spinosae 35-45 part, Poria cum Radix Pini 35-45 part, Radix Polygalae 25-35 part, stir-fry Fructus Foeniculi 45-55 part, Radix Aucklandiae 45-55 part, Massa Medicata Fermentata 95-105 part, Rhizoma Atractylodis Macrocephalae 45-55 part, Cortex Magnoliae Officinalis 55-65 part, Fructus Aurantii 45-55 part, Radix Glycyrrhizae 45-55 part.
And, the Chinese medicine composition of said treatment Ketosis, it constitutes component and parts by weight are:
80 parts of Radix Codonopsis, 80 parts of Rhizoma Atractylodis, 60 parts of the Radixs Astragali, 60 parts of Flos Loniceraes, 100 parts of Herba Houttuyniae, 50 parts in Poria, 60 parts of Radix Angelicae Sinensis, 50 parts of Herba Leonuris, 40 parts of Rhizoma Chuanxiongs, 60 parts of Radix Paeoniae Rubra, 60 parts in Radix Rehmanniae Preparata, 80 parts of Fructus Amomis, 40 parts of Semen Ziziphi Spinosaes, 40 parts of Poria cum Radix Pinis, 30 parts of Radix Polygalaes, 50 parts in Fructus Foeniculi of stir-fry, 50 parts of the Radix Aucklandiae, 100 parts of Massa Medicata Fermentata, 50 parts of the Rhizoma Atractylodis Macrocephalaes, 60 parts of Cortex Magnoliae Officinalis, 50 parts of Fructus Aurantiis, 50 parts in Radix Glycyrrhizae.
And the instructions of taking of the Chinese medicine composition of said treatment Ketosis is following: each Chinese medicinal components of Chinese medicine composition of said treatment Ketosis is ground to form fine powder, and boiled water reconstitutes, and waits temperature and irritates clothes, 1 dose/day.
Advantage of the present invention and beneficial effect are:
1, the Chinese medicine composition compatibility that the present invention relates to is simple, and manufacture method is simple, with low cost, safe and reliable, and sick cattle alleviates in symptom after taking medicine news speed, very fast rehabilitation, evident in efficacy, uses this treatment by Chinese herbs Ketosis 358 examples, and cure rate reaches 100%.
2, the Chinese medicine composition that the present invention relates to is the rule of treatment with air making-up and spleen enlivening, blood circulation promoting and enriching, the Radix Codonopsis invigorating the spleen and replenishing QI in the composition, spleen invigorating lung benefiting; Rhizoma Atractylodis can be drying damp and strengthening spleen, wind-damp dispelling; The Radix Astragali has the effect that benefiting QI for strengthening the superficies, arresting sweating take off, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema admittedly; Flos Lonicerae has the effect of heat-clearing and toxic substances removing.
The specific embodiment
Through specific embodiment the present invention is made further detailed description below, following examples are descriptive, are not determinate, can not limit protection scope of the present invention with this.
Embodiment 1
A kind of Chinese medicine composition of treating Ketosis, its composition and weight are following:
Radix Codonopsis 80 restrains, Rhizoma Atractylodis 80 restrain, the Radix Astragali 60 restrains, Flos Lonicerae 60 restrains, Herba Houttuyniae 100 restrains, Poria 50 restrains, Radix Angelicae Sinensis 60 restrains, Herba Leonuri 50 restrains, Rhizoma Chuanxiong 40 restrains, Radix Paeoniae Rubra 60 restrains, Radix Rehmanniae Preparata 60 restrains, Fructus Amomi 80 restrains, Semen Ziziphi Spinosae 40 restrains, Poria cum Radix Pini 40 restrains, Radix Polygalae 30 restrains, stir-fry Fructus Foeniculi 50 restrains, the Radix Aucklandiae 50 restrains, Massa Medicata Fermentata 100 restrains, the Rhizoma Atractylodis Macrocephalae 50 restrains, Cortex Magnoliae Officinalis 60 restrains, Fructus Aurantii 50 restrains, Radix Glycyrrhizae 50 restrains.
Each Chinese medicinal components of Chinese medicine composition of above-mentioned treatment Ketosis is ground to form fine powder, and boiled water reconstitutes, and waits temperature and irritates clothes, 1 dose/day.
Clinical experiment:
Embodiment 1
Pueraria lobota is raised the ill prescription on individual diagnosis in 16 days of 5 years old cows in postpartum.
The main suit: puerperal, all were normal.Forage reduces before three days, and the milk amount is reduced to 13 kilograms for 26 kilograms by daily output.Clinical examination: 38.2 ℃ of body temperature, heart beating 90 times/minute is breathed 40 times/minute, and a small amount of grass that searches for food does not eat concentrate, becomes thin.Stool is normal, and urine has the Fructus Mali pumilae flavor and bubble is arranged.
Adopt 5 milliliters of urine samples, use the ROSSShi method, the check of urine ketone is positive.
The side is the same with Chinese medicine, and decocting is waited temperature and irritated clothes, 1 dose/day, serve on 5 doses.After 7 days, sick timothy material is as usual, and breast amount day increases to 23 kilograms, and the urine sample ketoboidies is negative.
Embodiment 2
The Shandong is raised 14 years old Fresian and is examined over 10 days puerperal.
The main suit: do not eat concentrate, happiness food green forage, milk production reduces day by day.This noon, sudden onset was turn-taked to wall, astasia, and the napex muscle rigidity, excited uneasy.Inspection: 38.4 ℃ of body temperature, lift tail, sky is chewed and is ground one's teeth in sleep, and sensation is responsive, disorderly licks food skin, roars, and muscular tremor recovers normal after 80 minutes.Occur nervous symptoms after 6 hours again, examine and be ketoacidosis.
Check: 31 milligrams/1000 milliliters of blood ketone, urine ketone (the using the ROSSShi method) positive; 39 milligrams/100 milliliters of breast ketone.Be diagnosed as the nerve ketoacidosis.
The side uses treatment by Chinese herbs, and decocting is waited temperature and irritated clothes, 1 dose/day, serve on 3 doses.Sick timothy material is normal after 5 days, and the breast amount significantly rises, recovery from illness.Paid a return visit on 10th, more not recurrence.
Embodiment 3
Use this treatment by Chinese herbs Ketosis 58 examples, cure rate reaches 86%.

Claims (3)

1. Chinese medicine composition of treating Ketosis, it is characterized in that: its component by following parts by weight constitutes:
Radix Codonopsis 75-85 part, Rhizoma Atractylodis 75-85 part, Radix Astragali 55-65 part, Flos Lonicerae 55-65 part, Herba Houttuyniae 95-105 part, Poria 45-55 part, Radix Angelicae Sinensis 55-65 part, Herba Leonuri 45-55 part, Rhizoma Chuanxiong 35-45 part, Radix Paeoniae Rubra 55-65 part, Radix Rehmanniae Preparata 55-65 part, Fructus Amomi 75-85 part, Semen Ziziphi Spinosae 35-45 part, Poria cum Radix Pini 35-45 part, Radix Polygalae 25-35 part, stir-fry Fructus Foeniculi 45-55 part, Radix Aucklandiae 45-55 part, Massa Medicata Fermentata 95-105 part, Rhizoma Atractylodis Macrocephalae 45-55 part, Cortex Magnoliae Officinalis 55-65 part, Fructus Aurantii 45-55 part, Radix Glycyrrhizae 45-55 part.
2. the Chinese medicine composition of treatment Ketosis according to claim 1 is characterized in that: its component by following parts by weight constitutes:
80 parts of Radix Codonopsis, 80 parts of Rhizoma Atractylodis, 60 parts of the Radixs Astragali, 60 parts of Flos Loniceraes, 100 parts of Herba Houttuyniae, 50 parts in Poria, 60 parts of Radix Angelicae Sinensis, 50 parts of Herba Leonuris, 40 parts of Rhizoma Chuanxiongs, 60 parts of Radix Paeoniae Rubra, 60 parts in Radix Rehmanniae Preparata, 80 parts of Fructus Amomis, 40 parts of Semen Ziziphi Spinosaes, 40 parts of Poria cum Radix Pinis, 30 parts of Radix Polygalaes, 50 parts in Fructus Foeniculi of stir-fry, 50 parts of the Radix Aucklandiae, 100 parts of Massa Medicata Fermentata, 50 parts of the Rhizoma Atractylodis Macrocephalaes, 60 parts of Cortex Magnoliae Officinalis, 50 parts of Fructus Aurantiis, 50 parts in Radix Glycyrrhizae.
3. the Chinese medicine composition of treatment Ketosis according to claim 1; It is characterized in that: the instructions of taking of said Chinese medicine composition is following: each Chinese medicinal components of Chinese medicine composition of said treatment Ketosis is ground to form fine powder; Boiled water reconstitutes, and waits temperature and irritates clothes, 1 dose/day.
CN2011102451149A 2011-08-25 2011-08-25 Traditional Chinese medicine composition for treating cow ketosis Expired - Fee Related CN102247570B (en)

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Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103947904B (en) * 2014-05-15 2017-11-28 宁夏锐盛明杰知识产权咨询有限公司 A kind of preparation method for improving cow rumen flora glucose precursor thing
CN105053633A (en) * 2015-07-31 2015-11-18 无为县金宝生态农业开发有限公司 Poultry physique improving Chinese herbal medicinal composite forage and preparation method thereof
CN105663989A (en) * 2016-03-21 2016-06-15 中国农业科学院兰州畜牧与兽药研究所 Traditional Chinese medicine composition for preventing and treating cow digestion type ketosis and preparation method thereof
CN114343066B (en) * 2022-01-17 2024-02-20 河北省畜牧兽医研究所 Feed additive for preventing and treating ketosis of dairy cows and improving production and reproductive performance thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
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张富林等.中西医结合治疗奶牛酮病.《中兽医医药杂志》.2005,(第3期),48-49. *
王军等.奶牛酮病的中西医结合治疗及预防措施.《农技服务》.2008,第25卷(第7期),77-79. *

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Application publication date: 20111123

Assignee: Sky agriculture (Tianjin) Biological Technology Co., Ltd.

Assignor: Gert bio Pharmaceutical (Tianjin) Co. Ltd.

Contract record no.: 2013120000046

Denomination of invention: Traditional Chinese medicine composition for treating cow ketosis

Granted publication date: 20120725

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Record date: 20130910

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