CN102240369B - Traditional Chinese medicine preparation for treating functional dyspepsia - Google Patents

Traditional Chinese medicine preparation for treating functional dyspepsia Download PDF

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Publication number
CN102240369B
CN102240369B CN2011101581380A CN201110158138A CN102240369B CN 102240369 B CN102240369 B CN 102240369B CN 2011101581380 A CN2011101581380 A CN 2011101581380A CN 201110158138 A CN201110158138 A CN 201110158138A CN 102240369 B CN102240369 B CN 102240369B
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chinese medicine
medicine preparation
traditional chinese
functional dyspepsia
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CN102240369A (en
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张晶
满涛
赵兴玲
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Zhang Jing
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating functional dyspepsia. Functional dyspepsia can be included in the category of epigastric fullness syndrome, commonly diagnosed incoordination between the liver and the stomach and incoordination between the spleen and the stomach. Therefore, traditional Chinese herbal medicines having the efficacies of strengthening the spleen, consolidating the constitution, reinforcing the spleen, invigorating qi, harmonizing the stomach and lowering adverse qi are selected to be decocted into a decoction for patients to take, wherein the traditional Chinese herbal medicines comprise: red peony root, bighead atractylodes rhizome, cimicifugae foetidae, fried rice-grain sprout, tuckahoe, astragalus root, cassia twig, chrysanthemum, small fennel, costus root, immature bitter orange, betel palm, magnolia obavata, angelica sinensis and radish seed. Proven by clinical tests, the total effective rate reaches 95.7%, the therapeutic effect is obviously better than that of western medicines, and the traditional Chinese medicine preparation has low treatment cost, small side effect and worth of wide clinical popularization and application.

Description

A kind of Chinese medicine preparation of treating functional dyspepsia
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine preparation of treating functional dyspepsia.
Background technology
Functional dyspepsia is digestive system commonly encountered diseases, frequently-occurring disease, with continue or repeated relapsing epigastrium distension, dull pain, early full, belch, acid regurgitation, anorexia, feel sick, vomiting, etc. syndrome be main clinical manifestation.In treatment, follow the principle of Comprehensive Treatment and individualized treatment.Set up good living habit, avoid cigarette, wine and take NSAID.Drug therapy does not still have specific drug at present, adheres to symptomatic treatment, for being the patient of cardinal symptom with the upper abdominal pain, can select gastric acid inhibitory secretion medicine; For being the patient of cardinal symptom, can select short digestive tract power reinforcing medicine such as domperidone, cisapride etc. with big belly, early full belch.But these medication effects are poor, and side effect is big.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine preparation of treating functional dyspepsia, functional dyspepsia can be concluded the category of " painful abdominal mass " in the traditional Chinese medical science, card incoordination between the liver and stomach, the incoordination between the spleen and stomach of belonging to more, and treatment should consolidates in spleen invigorating, and ridging QI invigorating, stomach function regulating lead to and fall.
The objective of the invention is to realize that through following technical scheme the Chinese medicine preparation of this treatment functional dyspepsia is processed by following parts by weight of Chinese traditional medicine: Radix Paeoniae Rubra 9-13 part, Rhizoma Atractylodis Macrocephalae 10-13 part, Rhizoma Cimicifugae 7-9 part, Fructus Setariae Germinatus (parched) 9-13 part, Poria 10-15 part, Radix Astragali 7-9 part, Ramulus Cinnamomi 9-13 part, Flos Chrysanthemi 10-13 part, Fructus Foeniculi 6-9 part, Radix Aucklandiae 10-15 part, Fructus Aurantii Immaturus 7-11 part, Semen Arecae 7-11 part, Cortex Magnoliae Officinalis 9-13 part, Radix Angelicae Sinensis 10-15 part, Semen Raphani 9-13 part.
Preferably, the Chinese medicine preparation of this treatment functional dyspepsia is processed by following parts by weight of Chinese traditional medicine: 11 parts of Radix Paeoniae Rubra, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 8 parts of Rhizoma Cimicifugaes, 11 parts of Fructus Setariae Germinatus (parched), 13 parts in Poria, 8 parts of the Radixs Astragali, 12 parts of Ramulus Cinnamomi, 11 parts of Flos Chrysanthemis, 7 parts of Fructus Foeniculi, 13 parts of the Radix Aucklandiae, 9 parts of Fructus Aurantii Immaturuss, 9 parts of Semen Arecaes, 11 parts of Cortex Magnoliae Officinalis, 13 parts of Radix Angelicae Sinensis, 11 parts of Semen Raphanis.
Radix Paeoniae Rubra in the side, the Rhizoma Atractylodis Macrocephalae, Rhizoma Cimicifugae, Fructus Setariae Germinatus, Poria, Radix Astragali invigorating the spleen and benefiting QI and tonify deficiency; Ramulus Cinnamomi, Flos Chrysanthemi, Fructus Foeniculi, the Radix Aucklandiae, Fructus Aurantii Immaturus regulating qi-flowing for harmonizing stomach are equipped with Semen Arecae, Cortex Magnoliae Officinalis, Radix Angelicae Sinensis, Semen Raphani circulation of qi promoting intestinal stasis relieving with the turbid descending, and relieving distension removes full; All medicine phases 5; Have in the liter and fall, invigorating middle warmer has and disappears, thereby makes the prosperous and clearing heat in QI system liter of temper; Turbid the falling of stomach and the gas that stagnates disappears, clinical practice is so can obtain satisfactory effect.
Clinical data
1, all cases of physical data are from the court's outpatient service, inclusion criteria: (1) has symptoms such as in various degree upper abdomen distension, singultus, pain, inappetence; (2) above-mentioned symptom at least the persistent period more than 3 months; (3) get rid of organic disease through inspections such as gastroscope, digital gastrointestinal, B ultrasonic.Patient to meeting above condition is divided into treatment group and matched group at random according to the prescription on individual diagnosis order.70 examples are organized in treatment, male's 31 examples wherein, women's 39 examples, age 22-69 year, average 35.5 years old; Matched group 50 examples, male's 18 examples, women's 32 examples, age 21-67 year, average 36.5 years old; Two groups of situation are through statistical procedures, and there was no significant difference has comparability.
2, Therapeutic Method treatment group: fry in shallow oil into decoction with Chinese medicine preparation of the present invention, get Radix Paeoniae Rubra 11g, Rhizoma Atractylodis Macrocephalae 12g, Rhizoma Cimicifugae 8g, Fructus Setariae Germinatus (parched) 11g, Poria 13g, Radix Astragali 8g, Ramulus Cinnamomi 12g, Flos Chrysanthemi 11g, Fructus Foeniculi 7g, Radix Aucklandiae 13g, Fructus Aurantii Immaturus 9g, Semen Arecae 9g, Cortex Magnoliae Officinalis 11g, Radix Angelicae Sinensis 13g, Semen Raphani 11g.1 dose of every day, decocting 2 times, extracting juice 500-600ml altogether, divide 2 times oral, 10 days is a course of treatment.Matched group: omeprazole enteric-coated 20mg, oral every day 2 times, the person adds diazepam 20mg to have the insomnia and dreamful sleep, and the person that has the Helicobacter pylori infection is with triple therapy or the anti-treatment of helicobacter pylori of quadruple chemotherapy, and 10 days is a course of treatment.
3, criterion of therapeutical effect is according to the diagnostic criteria of new the 6th edition internal medicine teaching material to definition combination China practical situation of functional dyspepsia, and draft criterion of therapeutical effect: recovery from illness: clinical symptom disappearance, do not recur half a year.Produce effects: cardinal symptom disappears, and meeting society or stress by chance has slight epigastric discomfort sense, but not influence work life.Take a turn for the better: clinical symptoms obviously alleviates, but not complete obiteration.Invalid: clinical symptoms is not improved or improves not obvious.
4, therapeutic outcome treatment group 41 examples of fully recovering, produce effects 21 examples, 5 examples that take a turn for the better, invalid 3 examples, total effective rate about 95.7%; Matched group 18 examples of fully recovering, produce effects 11 examples, 7 examples that take a turn for the better, invalid 14 examples, total effective rate about 72%.
5, model case patient Lee, woman, 51 years old, the worker of enterprise.First visit on August 2 in 2006, gastral cavilty distension, poor appetite, singultus, inappetence, insomnia and dreamful sleep surplus being chief complaint half a year, it is not good to obey western medicine result time and again.Gastroscopy on same day gastric mucosa is smooth congested slightly, and helicobacter pylori is negative, gets rid of occupying lesion through other auxiliary examinations, so with Chinese medicine preparation treatment of the present invention.Took medicine 10 days, stomachache, distension obviously alleviate, and appetite is cumulative, and sleep obviously improves; Take medicine two courses of treatment, subjective symptoms disappears; Continuous again clothes are consolidated a course of treatment.Follow up a case by regular visits to and do not see recurrence in 1 year.
The specific embodiment
Embodiment one: get Radix Paeoniae Rubra 11g, Rhizoma Atractylodis Macrocephalae 12g, Rhizoma Cimicifugae 8g, Fructus Setariae Germinatus (parched) 11g, Poria 13g, Radix Astragali 8g, Ramulus Cinnamomi 12g, Flos Chrysanthemi 11g, Fructus Foeniculi 7g, Radix Aucklandiae 13g, Fructus Aurantii Immaturus 9g, Semen Arecae 9g, Cortex Magnoliae Officinalis 11g, Radix Angelicae Sinensis 13g, Semen Raphani 11g.1 dose of every day, decocting 2 times, extracting juice 550ml altogether, divide 2 times oral.
Embodiment two: get Radix Paeoniae Rubra 9g, Rhizoma Atractylodis Macrocephalae 13g, Rhizoma Cimicifugae 7g, Fructus Setariae Germinatus (parched) 9g, Poria 15g, Radix Astragali 9g, Ramulus Cinnamomi 13g, Flos Chrysanthemi 10g, Fructus Foeniculi 6g, Radix Aucklandiae 10g, Fructus Aurantii Immaturus 7g, Semen Arecae 11g, Cortex Magnoliae Officinalis 13g, Radix Angelicae Sinensis 10g, Semen Raphani 9g.1 dose of every day, decocting 2 times, extracting juice 550ml altogether, divide 2 times oral.
Embodiment three: get Radix Paeoniae Rubra 13g, Rhizoma Atractylodis Macrocephalae 10g, Rhizoma Cimicifugae 9g, Fructus Setariae Germinatus (parched) 13g, Poria 10g, Radix Astragali 7g, Ramulus Cinnamomi 9g, Flos Chrysanthemi 13g, Fructus Foeniculi 9g, Radix Aucklandiae 15g, Fructus Aurantii Immaturus 11g, Semen Arecae 7g, Cortex Magnoliae Officinalis 9g, Radix Angelicae Sinensis 15g, Semen Raphani 13g.1 dose of every day, decocting 2 times, extracting juice 550ml altogether, divide 2 times oral.

Claims (2)

1. Chinese medicine preparation of treating functional dyspepsia is characterized in that this Chinese medicine preparation processed by following parts by weight of Chinese traditional medicine: Radix Paeoniae Rubra 9-13 part, Rhizoma Atractylodis Macrocephalae 10-13 part, Rhizoma Cimicifugae 7-9 part, Fructus Setariae Germinatus (parched) 9-13 part, Poria 10-15 part, Radix Astragali 7-9 part, Ramulus Cinnamomi 9-13 part, Flos Chrysanthemi 10-13 part, Fructus Foeniculi 6-9 part, Radix Aucklandiae 10-15 part, Fructus Aurantii Immaturus 7-11 part, Semen Arecae 7-11 part, Cortex Magnoliae Officinalis 9-13 part, Radix Angelicae Sinensis 10-15 part, Semen Raphani 9-13 part.
2. a kind of Chinese medicine preparation of treating functional dyspepsia according to claim 1 is characterized in that this Chinese medicine preparation processed by following parts by weight of Chinese traditional medicine: 11 parts of Radix Paeoniae Rubra, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 8 parts of Rhizoma Cimicifugaes, 11 parts of Fructus Setariae Germinatus (parched), 13 parts in Poria, 8 parts of the Radixs Astragali, 12 parts of Ramulus Cinnamomi, 11 parts of Flos Chrysanthemis, 7 parts of Fructus Foeniculi, 13 parts of the Radix Aucklandiae, 9 parts of Fructus Aurantii Immaturuss, 9 parts of Semen Arecaes, 11 parts of Cortex Magnoliae Officinalis, 13 parts of Radix Angelicae Sinensis, 11 parts of Semen Raphanis.
CN2011101581380A 2011-06-02 2011-06-02 Traditional Chinese medicine preparation for treating functional dyspepsia Expired - Fee Related CN102240369B (en)

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CN105396040A (en) * 2015-12-14 2016-03-16 青岛市市立医院 Traditional Chinese medicine composition for treating dyspepsia
CN105560689A (en) * 2015-12-31 2016-05-11 张冬 Traditional Chinese medicinal preparation for treating indigestion
CN105770738A (en) * 2016-04-03 2016-07-20 徐彦玲 Traditional Chinese medicine preparation for treating functional dyspepsia and preparation method of traditional Chinese medicine preparation

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* Cited by examiner, † Cited by third party
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CN1899582A (en) * 2006-07-20 2007-01-24 孙喜灵 Medicine for treating chronic gastritis and its preparing method

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1899582A (en) * 2006-07-20 2007-01-24 孙喜灵 Medicine for treating chronic gastritis and its preparing method

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