CN105126012A - Traditional Chinese medicinal preparation for treating gastric cancer and preparation method of traditional Chinese medicinal preparation - Google Patents
Traditional Chinese medicinal preparation for treating gastric cancer and preparation method of traditional Chinese medicinal preparation Download PDFInfo
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Abstract
The invention belongs to the field of a traditional Chinese medicinal preparation, and in particular relates to a traditional Chinese medicinal preparation for treating gastric cancer and a preparation method of the traditional Chinese medicinal preparation, wherein the traditional Chinese medicinal preparation consists of the following raw materials: cinobufotalin powder, gecko powder, euphorbia helioscopia, centipede, pseudo-ginseng, American ginseng, codonopsis pilosula, radix sophorae flavescentis, curcuma zedoary, astragalus membranaceus, angelica, ligusticum wallichii, radix paeoniae alba, prepared rehmannia root, raw rhubarb, Paris polyphylla, rhizoma corydalis, pollen, ginger processed rhizoma arisaematis, ginger processed pinellia, sculellaria barbata, dandelion powder, inula flower, poria cocos, bighead atractylodes rhizome, liquorice, dried orange peel, rhizoma polygonati powder, amomum cardamomum, fructus amomi, leech, dark plum, myrrh, mangnolia officinalis and endothelium corneum gigeriae galli. On the basis of empirical prescription for years, the various raw materials and corresponding proportions of the traditional Chinese medicinal preparation disclosed by the invention are screened and obtained, and the various raw materials are coordinated to achieve a significant curative effect; the traditional Chinese medicinal preparation disclosed by the invention is easily available in various raw materials, simple and convenient in preparation method, low in cost, economic and applicable, and unique in curative effect on patients of gastric cancer; and the traditional Chinese medicinal preparation can be used for greatly reducing pain in patients from chemotherapy and surgery, and meanwhile the traditional Chinese medicinal preparation can be used for reducing economic burden in the patients.
Description
Technical field
The invention belongs to field of traditional Chinese, be specifically related to a kind of Chinese medicine preparation being used for the treatment of gastric cancer and preparation method thereof.
Background technology
Gastric cancer is modal malignant tumor, and sickness rate occupies the first place of whole body malignant tumor, and mortality rate is first of common cancer, though motherland's medical science is without gastric cancer name of disease, in conjunction with disease analysis, this disease belongs to gastric abscess, regurgitation, the cancer of the esophagus, and fullness in the epigastrium especially referring to the abcess of the abdomen in ancient times disease is long-pending waits category.Its pathogenesis mostly is unhygienic diet, transformation failure of spleen, phlegm and qi stasis, and pyretic toxicity blood stasis gathers in bulk and sends out this disease.Should with dispersing the stagnated liver-QI for regulating the stomach, sending down the abnormal ascending QI pain relieving in treatment, heat clearing away cold expelling is main.。This disease can take radical operation to cure in early days, but still lacks effective treatment means for middle and advanced stage patient, at present, Therapeutic Method still based on excision, combined with chemotherapy, radiotherapy and immunotherapy, but all do not reach ideal effect, and medical expense is expensive.Treatment by Chinese herbs cancer more and more comes into one's own.Adopt Chinese traditional treatment cancer, generally from entirety, both considered topical therapeutic, and took again the method for the body resistance strengthening and constitution consolidating, and had important effect for the local symptom and overall health of patients improving patient; Treatment side effect is little.Therefore, need a kind of evident in efficacy in clinical treatment, the Chinese medicine preparation of the treatment gastric cancer that side effect is less, economic.
Summary of the invention
The present invention, in order to solve the problems of the technologies described above, provides a kind of Chinese medicine preparation being used for the treatment of gastric cancer and preparation method thereof, and the present invention is in 10 years-nineteen ninety-fives in 1986 to select ancient books proved recipe, and treatment gastric cancer 93 is routine, evident in efficacy.
In order to reach above-mentioned technique effect, technical scheme of the present invention comprises:
A kind of Chinese medicine preparation being used for the treatment of gastric cancer, comprise the raw material of following parts by weight: magnificent toad 5 ~ 15 parts, Gekko Swinhonis 3 ~ 8 parts, Herba Euphorbiae Helioscopiae 10 ~ 20 parts, Scolopendra 1 ~ 5, Radix Notoginseng 5 ~ 15 parts, Radix Panacis Quinquefolii 5 ~ 15 parts, Radix Codonopsis 10 ~ 20 parts, Radix Sophorae Flavescentis 5 ~ 15 parts, Rhizoma Curcumae 4 ~ 16 parts, the Radix Astragali 10 ~ 20 parts, Radix Angelicae Sinensis 4 ~ 16 parts, Rhizoma Chuanxiong 4 ~ 16 parts, the Radix Paeoniae Alba 10 ~ 20 parts, 10 ~ 20 parts, Radix Rehmanniae Preparata, Radix Et Rhizoma Rhei 4 ~ 16 parts, Rhizoma Paridis 5 ~ 15 parts, Rhizoma Corydalis 5 ~ 15 parts, pollen 5 ~ 15 parts, Jiang Nanxing 5 ~ 15 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 5 ~ 15 parts, Herba Scutellariae Barbatae 10 ~ 20 parts, Herba Taraxaci 10 ~ 20 parts, Flos Inulae 5 ~ 15 parts, 5 ~ 15 parts, Poria, the Rhizoma Atractylodis Macrocephalae 5 ~ 15 parts, 4 ~ 16 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 4 ~ 16 parts, Rhizoma Polygonati 5 ~ 15 parts, Fructus Amomi Rotundus 4 ~ 16 parts, Fructus Amomi 4 ~ 16 parts, Hirudo 4 ~ 16 parts, Fructus Mume 5 ~ 15 parts, Myrrha 5 ~ 15 parts, Cortex Magnoliae Officinalis 5 ~ 15 parts, Endothelium Corneum Gigeriae Galli 5 ~ 15 parts.
Preferably, comprise the raw material of following parts by weight: magnificent toad 10 parts, Gekko Swinhonis 6 parts, Herba Euphorbiae Helioscopiae 15 parts, Scolopendra 3, Radix Notoginseng 10 parts, Radix Panacis Quinquefolii 10 parts, Radix Codonopsis 15 parts, Radix Sophorae Flavescentis 10 parts, Rhizoma Curcumae 9 parts, the Radix Astragali 15 parts, Radix Angelicae Sinensis 9 parts, Rhizoma Chuanxiong 9 parts, the Radix Paeoniae Alba 10 parts, 10 parts, Radix Rehmanniae Preparata, Radix Et Rhizoma Rhei 6 parts, Rhizoma Paridis 10 parts, Rhizoma Corydalis 10 parts, pollen 10 parts, Jiang Nanxing 10 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10 parts, Herba Scutellariae Barbatae 15 parts, Herba Taraxaci 15 parts, Flos Inulae 10 parts, 10 parts, Poria, the Rhizoma Atractylodis Macrocephalae 10 parts, 6 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 6 parts, Rhizoma Polygonati 10 parts, Fructus Amomi Rotundus 6 parts, Fructus Amomi 6 parts, Hirudo 6 parts, Fructus Mume 10 parts, Myrrha 10 parts, Cortex Magnoliae Officinalis 10 parts, Endothelium Corneum Gigeriae Galli 10 parts
Be used for the treatment of a preparation method for the Chinese medicine preparation of gastric cancer, comprise the following steps: the raw material getting following parts by weight: magnificent toad 5 ~ 15 parts, Gekko Swinhonis 3 ~ 8 parts, Herba Euphorbiae Helioscopiae 10 ~ 20 parts, Scolopendra 1 ~ 5, Radix Notoginseng 5 ~ 15 parts, Radix Panacis Quinquefolii 5 ~ 15 parts, Radix Codonopsis 10 ~ 20 parts, Radix Sophorae Flavescentis 5 ~ 15 parts, Rhizoma Curcumae 4 ~ 16 parts, the Radix Astragali 10 ~ 20 parts, Radix Angelicae Sinensis 4 ~ 16 parts, Rhizoma Chuanxiong 4 ~ 16 parts, the Radix Paeoniae Alba 10 ~ 20 parts, 10 ~ 20 parts, Radix Rehmanniae Preparata, Radix Et Rhizoma Rhei 4 ~ 16 parts, Rhizoma Paridis 5 ~ 15 parts, Rhizoma Corydalis 5 ~ 15 parts, pollen 5 ~ 15 parts, Jiang Nanxing 5 ~ 15 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 5 ~ 15 parts, Herba Scutellariae Barbatae 10 ~ 20 parts, Herba Taraxaci 10 ~ 20 parts, Flos Inulae 5 ~ 15 parts, 5 ~ 15 parts, Poria, the Rhizoma Atractylodis Macrocephalae 5 ~ 15 parts, 4 ~ 16 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 4 ~ 16 parts, Rhizoma Polygonati 5 ~ 15 parts, Fructus Amomi Rotundus 4 ~ 16 parts, Fructus Amomi 4 ~ 16 parts, Hirudo 4 ~ 16 parts, Fructus Mume 5 ~ 15 parts, Myrrha 5 ~ 15 parts, Cortex Magnoliae Officinalis 5 ~ 15 parts, Endothelium Corneum Gigeriae Galli 5 ~ 15 parts, decocts with water three times, merges three decoction liquor after filtering, obtain concentrated solution by concentrated for the decoction liquor after merging, treat that described concentrated solution is cooled to room temperature, add ethanol, place 24h, get supernatant and reclaim ethanol, add simple syrup, adjust ph, add water to 1000ml again, stir evenly rear leaving standstill, filter, get filtrate sterilizing and get final product.
Further, get described magnificent toad 10 parts, Gekko Swinhonis 6 parts, Herba Euphorbiae Helioscopiae 15 parts, Scolopendra 3, Radix Notoginseng 10 parts, Radix Panacis Quinquefolii 10 parts, Radix Codonopsis 15 parts, Radix Sophorae Flavescentis 10 parts, Rhizoma Curcumae 9 parts, the Radix Astragali 15 parts, Radix Angelicae Sinensis 9 parts, Rhizoma Chuanxiong 9 parts, the Radix Paeoniae Alba 10 parts, 10 parts, Radix Rehmanniae Preparata, Radix Et Rhizoma Rhei 6 parts, Rhizoma Paridis 10 parts, Rhizoma Corydalis 10 parts, pollen 10 parts, Jiang Nanxing 10 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10 parts, Herba Scutellariae Barbatae 15 parts, Herba Taraxaci 15 parts, Flos Inulae 10 parts, 10 parts, Poria, the Rhizoma Atractylodis Macrocephalae 10 parts, 6 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 6 parts, Rhizoma Polygonati 10 parts, Fructus Amomi Rotundus 6 parts, Fructus Amomi 6 parts, Hirudo 6 parts, Fructus Mume 10 parts, Myrrha 10 parts, Cortex Magnoliae Officinalis 10 parts, Endothelium Corneum Gigeriae Galli 10 parts.
Further, during described concentrated solution 80 DEG C, relative density is 1.15-1.30.
Further, adding ethanol to ethanol content in described concentrated solution is 60%.
Further, described adjust ph is to 5.0-7.0.
Further, described sterilizing methods is 100 DEG C of sterilizing 30min.
Further, each amount of water of described decoction is 6.5-8.5 times of medical material cumulative volume, and each decocting time is 50min.
Beneficial effect of the present invention comprises:
1, the present invention is through proved recipe for many years, filters out each raw material of the present invention and corresponding proportioning, various raw material synergy, evident in efficacy; The present invention's each raw material used is easy to get, and preparation method is easy, cheap, economic and practical, has unique curative effect to patients with gastric cancer, greatly can reduce the misery that patient does chemotherapy and operation, also can reduce the financial burden of patient simultaneously.
2, Chinese medicine preparation being used for the treatment of gastric cancer of the present invention and preparation method thereof, by refining production technology, improve the extraction of effective ingredient, ensure that the stability of preparation, decrease therapeutic effect that the mass discrepancy due to preparation causes and reduce and the generation of untoward reaction.Oral liquid formulations form, taking dose is little, absorption is rapid, steady quality, be convenient for carrying, easily preserve, and is especially applicable to suitability for industrialized production.
Detailed description of the invention
Hereafter specifically will describe the specific embodiment of the invention in detail.It should be noted that the combination of technical characteristic or the technical characteristic described in following embodiment should not be considered to isolated, they can mutually be combined thus be reached better technique effect.
Embodiment 1
A kind of Chinese medicine preparation being used for the treatment of gastric cancer, it is characterized in that, comprise the raw material of following parts by weight: magnificent toad 5 parts, Gekko Swinhonis 8 parts, Herba Euphorbiae Helioscopiae 10 parts, Scolopendra 5, Radix Notoginseng 5 parts, Radix Panacis Quinquefolii 15 parts, Radix Codonopsis 10 parts, Radix Sophorae Flavescentis 15 parts, Rhizoma Curcumae 4 parts, the Radix Astragali 20 parts, Radix Angelicae Sinensis 4 parts, Rhizoma Chuanxiong 16 parts, the Radix Paeoniae Alba 10 parts, 20 parts, Radix Rehmanniae Preparata, Radix Et Rhizoma Rhei 4 parts, Rhizoma Paridis 15 parts, Rhizoma Corydalis 5 parts, pollen 15 parts, Jiang Nanxing 5 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15 parts, Herba Scutellariae Barbatae 10 parts, Herba Taraxaci 20 parts, Flos Inulae 5 parts, 15 parts, Poria, the Rhizoma Atractylodis Macrocephalae 5 parts, 16 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 4 parts, Rhizoma Polygonati 15 parts, Fructus Amomi Rotundus 4 parts, Fructus Amomi 16 parts, Hirudo 4 parts, Fructus Mume 15 parts, Myrrha 5 parts, Cortex Magnoliae Officinalis 15 parts, Endothelium Corneum Gigeriae Galli 5 parts.
Be used for the treatment of a preparation method for the Chinese medicine preparation of gastric cancer, comprise the following steps:
Get the raw material of following parts by weight: magnificent toad 5 parts, Gekko Swinhonis 8 parts, Herba Euphorbiae Helioscopiae 10 parts, Scolopendra 5, Radix Notoginseng 5 parts, Radix Panacis Quinquefolii 15 parts, Radix Codonopsis 10 parts, Radix Sophorae Flavescentis 15 parts, Rhizoma Curcumae 4 parts, the Radix Astragali 20 parts, Radix Angelicae Sinensis 4 parts, Rhizoma Chuanxiong 16 parts, the Radix Paeoniae Alba 10 parts, 20 parts, Radix Rehmanniae Preparata, Radix Et Rhizoma Rhei 4 parts, Rhizoma Paridis 15 parts, Rhizoma Corydalis 5 parts, pollen 15 parts, Jiang Nanxing 5 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15 parts, Herba Scutellariae Barbatae 10 parts, Herba Taraxaci 20 parts, Flos Inulae 5 parts, 15 parts, Poria, the Rhizoma Atractylodis Macrocephalae 5 parts, 16 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 4 parts, Rhizoma Polygonati 15 parts, Fructus Amomi Rotundus 4 parts, Fructus Amomi 16 parts, Hirudo 4 parts, Fructus Mume 15 parts, Myrrha 5 parts, Cortex Magnoliae Officinalis 15 parts, Endothelium Corneum Gigeriae Galli 5 parts, decoct with water three times, decoct 6.5 times that each amount of water is medical material cumulative volume, each decocting time is 50min, merge three decoction liquor after filtering, obtain concentrated solution by concentrated for the decoction liquor after merging, during concentrated solution 80 DEG C, relative density is 1.15, treat that described concentrated solution is cooled to room temperature, adding ethanol to ethanol content is 60%, places 24h, gets supernatant and reclaims ethanol, add simple syrup, adjust ph to 5.0, then add water to 1000ml, stir evenly rear leaving standstill, filter, get filtrate 100 DEG C of sterilizing 30min and get final product.
Embodiment 2
A kind of Chinese medicine preparation being used for the treatment of gastric cancer, it is characterized in that, comprise the raw material of following parts by weight: magnificent toad 10 parts, Gekko Swinhonis 6 parts, Herba Euphorbiae Helioscopiae 15 parts, Scolopendra 3, Radix Notoginseng 10 parts, Radix Panacis Quinquefolii 10 parts, Radix Codonopsis 15 parts, Radix Sophorae Flavescentis 10 parts, Rhizoma Curcumae 9 parts, the Radix Astragali 15 parts, Radix Angelicae Sinensis 9 parts, Rhizoma Chuanxiong 9 parts, the Radix Paeoniae Alba 10 parts, 10 parts, Radix Rehmanniae Preparata, Radix Et Rhizoma Rhei 6 parts, Rhizoma Paridis 10 parts, Rhizoma Corydalis 10 parts, pollen 10 parts, Jiang Nanxing 10 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10 parts, Herba Scutellariae Barbatae 15 parts, Herba Taraxaci 15 parts, Flos Inulae 10 parts, 10 parts, Poria, the Rhizoma Atractylodis Macrocephalae 10 parts, 6 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 6 parts, Rhizoma Polygonati 10 parts, Fructus Amomi Rotundus 6 parts, Fructus Amomi 6 parts, Hirudo 6 parts, Fructus Mume 10 parts, Myrrha 10 parts, Cortex Magnoliae Officinalis 10 parts, Endothelium Corneum Gigeriae Galli 10 parts.
Be used for the treatment of a preparation method for the Chinese medicine preparation of gastric cancer, comprise the following steps: the raw material China toad 10 parts getting following parts by weight, Gekko Swinhonis 6 parts, Herba Euphorbiae Helioscopiae 15 parts, Scolopendra 3, Radix Notoginseng 10 parts, Radix Panacis Quinquefolii 10 parts, Radix Codonopsis 15 parts, Radix Sophorae Flavescentis 10 parts, Rhizoma Curcumae 9 parts, the Radix Astragali 15 parts, Radix Angelicae Sinensis 9 parts, Rhizoma Chuanxiong 9 parts, the Radix Paeoniae Alba 10 parts, 10 parts, Radix Rehmanniae Preparata, Radix Et Rhizoma Rhei 6 parts, Rhizoma Paridis 10 parts, Rhizoma Corydalis 10 parts, pollen 10 parts, Jiang Nanxing 10 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10 parts, Herba Scutellariae Barbatae 15 parts, Herba Taraxaci 15 parts, Flos Inulae 10 parts, 10 parts, Poria, the Rhizoma Atractylodis Macrocephalae 10 parts, 6 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 6 parts, Rhizoma Polygonati 10 parts, Fructus Amomi Rotundus 6 parts, Fructus Amomi 6 parts, Hirudo 6 parts, Fructus Mume 10 parts, Myrrha 10 parts, Cortex Magnoliae Officinalis 10 parts, Endothelium Corneum Gigeriae Galli 10 parts, decoct with water three times, decoct 7.5 times that each amount of water is medical material cumulative volume, each decocting time is 50min, merge three decoction liquor after filtering, obtain concentrated solution by concentrated for the decoction liquor after merging, during concentrated solution 80 DEG C, relative density is 1.20, treat that described concentrated solution is cooled to room temperature, adding ethanol to ethanol content is 60%, places 24h, gets supernatant and reclaims ethanol, add simple syrup, adjust ph to 6.0, then add water to 1000ml, stir evenly rear leaving standstill, filter, get filtrate 100 DEG C of sterilizing 30min and get final product.
Embodiment 3
A kind of Chinese medicine preparation being used for the treatment of gastric cancer, it is characterized in that, comprise the raw material of following parts by weight: magnificent toad 15 parts, Gekko Swinhonis 3 parts, Herba Euphorbiae Helioscopiae 20 parts, Scolopendra 1, Radix Notoginseng 15 parts, Radix Panacis Quinquefolii 5 parts, Radix Codonopsis 20 parts, Radix Sophorae Flavescentis 5 parts, Rhizoma Curcumae 16 parts, the Radix Astragali 10 parts, Radix Angelicae Sinensis 16 parts, Rhizoma Chuanxiong 4 parts, the Radix Paeoniae Alba 20 parts, 10 parts, Radix Rehmanniae Preparata, Radix Et Rhizoma Rhei 16 parts, Rhizoma Paridis 5 parts, Rhizoma Corydalis 15 parts, pollen 5 parts, Jiang Nanxing 15 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 5 parts, Herba Scutellariae Barbatae 20 parts, Herba Taraxaci 10 parts, Flos Inulae 15 parts, 5 parts, Poria, the Rhizoma Atractylodis Macrocephalae 15 parts, 4 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 16 parts, Rhizoma Polygonati 5 parts, Fructus Amomi Rotundus 16 parts, Fructus Amomi 4 parts, Hirudo 16 parts, Fructus Mume 5 parts, Myrrha 15 parts, Cortex Magnoliae Officinalis 5 parts, Endothelium Corneum Gigeriae Galli 15 parts.
Be used for the treatment of a preparation method for the Chinese medicine preparation of gastric cancer, comprise the following steps: the raw material getting following parts by weight: magnificent toad 15 parts, Gekko Swinhonis 3 parts, Herba Euphorbiae Helioscopiae 20 parts, Scolopendra 1, Radix Notoginseng 15 parts, Radix Panacis Quinquefolii 5 parts, Radix Codonopsis 20 parts, Radix Sophorae Flavescentis 5 parts, Rhizoma Curcumae 16 parts, the Radix Astragali 10 parts, Radix Angelicae Sinensis 16 parts, Rhizoma Chuanxiong 4 parts, the Radix Paeoniae Alba 20 parts, 10 parts, Radix Rehmanniae Preparata, Radix Et Rhizoma Rhei 16 parts, Rhizoma Paridis 5 parts, Rhizoma Corydalis 15 parts, pollen 5 parts, Jiang Nanxing 15 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 5 parts, Herba Scutellariae Barbatae 20 parts, Herba Taraxaci 10 parts, Flos Inulae 15 parts, 5 parts, Poria, the Rhizoma Atractylodis Macrocephalae 15 parts, 4 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 16 parts, Rhizoma Polygonati 5 parts, Fructus Amomi Rotundus 16 parts, Fructus Amomi 4 parts, Hirudo 16 parts, Fructus Mume 5 parts, Myrrha 15 parts, Cortex Magnoliae Officinalis 5 parts, Endothelium Corneum Gigeriae Galli 15 parts, decoct with water three times, decoct 8.5 times that each amount of water is medical material cumulative volume, each decocting time is 50min, merge three decoction liquor after filtering, obtain concentrated solution by concentrated for the decoction liquor after merging, during concentrated solution 80 DEG C, relative density is 1.30, treat that described concentrated solution is cooled to room temperature, adding ethanol to ethanol content is 60%, places 24h, gets supernatant and reclaims ethanol, add simple syrup, adjust ph to 7.0, then add water to 1000ml, stir evenly rear leaving standstill, filter, get filtrate 100 DEG C of sterilizing 30min and get final product.
Embodiment 4 clinical experiment
Clinical data:
In 93 routine patients with gastric cancer male 62 example, account for 67%, women 31 example, account for 33%, the oldest person 81 years old, reckling 29 years old, wherein age 29-30 year person 6 example, 40-50 year person 25 example; 51-60 year person 33 example; More than 61 years old person 29 examples.Treat aforementioned 93 routine patients, make a definite diagnosis through hospital above county level x-ray canel barium meal contrast examination and gastroscope typing and histocytology pathologic finding, wherein early stage patient (tumor is at 1-3cm) 18 example, account for 19.36%, patient in mid-term (tumor is at 3.1-5cm) 44 is routine, account for 47.3%, patients with terminal (tumor is greater than more than 5cm) 31 example, account for the inappetence that 33.33% clinical manifestation all has weight not wait, upper limb is uncomfortable, the pernicious condition of illness such as to become thin, most of patients has long-term feeling sick, regurgitation, stomachache and gastric ulcer case history, small number of patients also has agnogenic hematemesis, the symptoms such as melena.93 routine patients with gastric cancer are taken Chinese medicine preparation of the present invention, daily twice.
By the unified national critical treatment malignant tumor efficacy assessment standard demonstration formulated of " up-to-date domestic and international disease treatment standard " level Ministry of Public Health.Cure: after treatment, symptom and the objective determination positive levy disappearance, and recover certain work capacity, Continuous Observation more than 3 years, without recidivist.
Clinical cure: after treatment, the positive sign of symptom and objective determination disappears substantially, and tumor regression half or over half, recovers certain work capacity, Continuous Observation half a year to one is year without recidivist.
Effective: after curing, cardinal symptom disappears, focus reduces or stablizes, and within Continuous Observation 2-6 month, does not develop.
Therapeutic outcome:
In the 93 routine patients observed, cure 32 examples (34.41%), clinical cure 34 example (36.5%), effective 24 examples (25%), invalid 3 examples (3.32%), total effective rate is 96.77%, through observing the most elder's medication of tumor block extinction time 141 days, the shortest person's medication 75 days, average administration time is 108 days.
Model case:
Case 1 Liu so-and-so, female, 41 years old, live lane, Gua Jiasi West Street, Hexi District, Tianjin.Patient has belch, acid regurgitation water, epigastric discomfort, the symptoms such as epigastric oppression block, the methods such as treatment can adopt invigorating the stomach and promoting digestion, broken stagnantly to invigorate blood circulation, Huoxue San " painful abdominal mass.Treated by Chinese medicine preparation of the present invention and be almost recovered for four months, condition is good, can be engaged in general physical work now.
Case 2 is permitted certain, man, within 49 years old, once had gastral cavilty portion pain medical history many decades, the pain increased recently, loss of appetite, because to become thin and melena increases the weight of gradually and removes certain hospital admission, through Wei Chang An film making and gastroscopy, be diagnosed as late gastric cancer, cannot perform the operation, chemotherapy can not be carried out due to weak, treated May 6 nineteen ninety-five by Chinese medicine preparation of the present invention, after one week, appetite increases, and symptom is clearly better, continue medication more than 3 months, pain disappears, and body weight increases by 6 kilograms, through Wei Chang An film making check, foci disappearance, no abnormality seen.
Have foregoing known, the present invention, through proved recipe for many years, filters out each raw material of the present invention and corresponding proportioning, various raw material synergy, evident in efficacy; The present invention's each raw material used is easy to get, and preparation method is easy, cheap, economic and practical, has unique curative effect to patients with gastric cancer, greatly can reduce the misery that patient does chemotherapy and operation, also can reduce the financial burden of patient simultaneously.
Above-mentioned detailed description is the illustrating of possible embodiments for invention, and this embodiment is also not used to limit the scope of the claims of the present invention, does not allly depart from equivalence of the present invention and implements or change, and all should be contained in the scope of the claims of the present invention.
In addition, those skilled in the art also can make various amendments in other form and details, interpolation and replacement in the claims in the present invention scope of disclosure and spirit.Certainly, the changes such as these various amendments made according to the present invention's spirit, interpolation and replacement, all should be included within the present invention's scope required for protection.
Claims (9)
1. be used for the treatment of a Chinese medicine preparation for gastric cancer, it is characterized in that, comprise the raw material of following parts by weight: magnificent toad 5 ~ 15 parts, Gekko Swinhonis 3 ~ 8 parts, Herba Euphorbiae Helioscopiae 10 ~ 20 parts, Scolopendra 1 ~ 5, Radix Notoginseng 5 ~ 15 parts, Radix Panacis Quinquefolii 5 ~ 15 parts,
partyjoin 10 ~ 20 parts, Radix Sophorae Flavescentis 5 ~ 15 parts, Rhizoma Curcumae 4 ~ 16 parts, the Radix Astragali 10 ~ 20 parts, Radix Angelicae Sinensis 4 ~ 16 parts, Rhizoma Chuanxiong 4 ~ 16 parts, the Radix Paeoniae Alba 10 ~ 20 parts, 10 ~ 20 parts, Radix Rehmanniae Preparata, Radix Et Rhizoma Rhei 4 ~ 16 parts, Rhizoma Paridis 5 ~ 15 parts, Rhizoma Corydalis 5 ~ 15 parts, pollen 5 ~ 15 parts, Jiang Nanxing 5 ~ 15 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 5 ~ 15 parts, Herba Scutellariae Barbatae 10 ~ 20 parts, Herba Taraxaci 10 ~ 20 parts, Flos Inulae 5 ~ 15 parts, 5 ~ 15 parts, Poria, the Rhizoma Atractylodis Macrocephalae 5 ~ 15 parts, 4 ~ 16 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 4 ~ 16 parts, Rhizoma Polygonati 5 ~ 15 parts, Fructus Amomi Rotundus 4 ~ 16 parts, Fructus Amomi 4 ~ 16 parts, Hirudo 4 ~ 16 parts, Fructus Mume 5 ~ 15 parts, Myrrha 5 ~ 15 parts, Cortex Magnoliae Officinalis 5 ~ 15 parts, Endothelium Corneum Gigeriae Galli 5 ~ 15 parts.
2. a kind of Chinese medicine preparation being used for the treatment of gastric cancer according to claim 1, is characterized in that, comprise the raw material of following parts by weight: magnificent toad 10 parts, Gekko Swinhonis 6 parts, Herba Euphorbiae Helioscopiae 15 parts, Scolopendra 3, Radix Notoginseng 10 parts, Radix Panacis Quinquefolii 10 parts,
partyjoin 15 parts, Radix Sophorae Flavescentis 10 parts, Rhizoma Curcumae 9 parts, the Radix Astragali 15 parts, Radix Angelicae Sinensis 9 parts, Rhizoma Chuanxiong 9 parts, the Radix Paeoniae Alba 10 parts, 10 parts, Radix Rehmanniae Preparata, Radix Et Rhizoma Rhei 6 parts, Rhizoma Paridis 10 parts, Rhizoma Corydalis 10 parts, pollen 10 parts, Jiang Nanxing 10 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10 parts, Herba Scutellariae Barbatae 15 parts, Herba Taraxaci 15 parts, Flos Inulae 10 parts, 10 parts, Poria, the Rhizoma Atractylodis Macrocephalae 10 parts, 6 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 6 parts, Rhizoma Polygonati 10 parts, Fructus Amomi Rotundus 6 parts, Fructus Amomi 6 parts, Hirudo 6 parts, Fructus Mume 10 parts, Myrrha 10 parts, Cortex Magnoliae Officinalis 10 parts, Endothelium Corneum Gigeriae Galli 10 parts.
3. one kind is used for the treatment of the preparation method of the Chinese medicine preparation of gastric cancer, it is characterized in that, comprise the following steps: the raw material getting following parts by weight: magnificent toad 5 ~ 15 parts, Gekko Swinhonis 3 ~ 8 parts, Herba Euphorbiae Helioscopiae 10 ~ 20 parts, Scolopendra 1 ~ 5, Radix Notoginseng 5 ~ 15 parts, Radix Panacis Quinquefolii 5 ~ 15 parts,
partyjoin 10 ~ 20 parts, Radix Sophorae Flavescentis 5 ~ 15 parts, Rhizoma Curcumae 4 ~ 16 parts, the Radix Astragali 10 ~ 20 parts, Radix Angelicae Sinensis 4 ~ 16 parts, Rhizoma Chuanxiong 4 ~ 16 parts, the Radix Paeoniae Alba 10 ~ 20 parts, 10 ~ 20 parts, Radix Rehmanniae Preparata, Radix Et Rhizoma Rhei 4 ~ 16 parts, Rhizoma Paridis 5 ~ 15 parts, Rhizoma Corydalis 5 ~ 15 parts, pollen 5 ~ 15 parts, Jiang Nanxing 5 ~ 15 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 5 ~ 15 parts, Herba Scutellariae Barbatae 10 ~ 20 parts, Herba Taraxaci 10 ~ 20 parts, Flos Inulae 5 ~ 15 parts, 5 ~ 15 parts, Poria, the Rhizoma Atractylodis Macrocephalae 5 ~ 15 parts, 4 ~ 16 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 4 ~ 16 parts, Rhizoma Polygonati 5 ~ 15 parts, Fructus Amomi Rotundus 4 ~ 16 parts, Fructus Amomi 4 ~ 16 parts, Hirudo 4 ~ 16 parts, Fructus Mume 5 ~ 15 parts, Myrrha 5 ~ 15 parts, Cortex Magnoliae Officinalis 5 ~ 15 parts, Endothelium Corneum Gigeriae Galli 5 ~ 15 parts, decoct with water three times, three decoction liquor are merged after filtering, concentrated solution is obtained by concentrated for the decoction liquor after merging, treat that described concentrated solution is cooled to room temperature, add ethanol, place 24h, get supernatant and reclaim ethanol, add simple syrup, adjust ph, add water to 1000ml again, stir evenly rear leaving standstill, filter, get filtrate sterilizing and get final product.
4. preparation method according to claim 3, is characterized in that, get described magnificent toad 10 parts, Gekko Swinhonis 6 parts, Herba Euphorbiae Helioscopiae 15 parts, Scolopendra 3, Radix Notoginseng 10 parts, Radix Panacis Quinquefolii 10 parts,
partyjoin 15 parts, Radix Sophorae Flavescentis 10 parts, Rhizoma Curcumae 9 parts, the Radix Astragali 15 parts, Radix Angelicae Sinensis 9 parts, Rhizoma Chuanxiong 9 parts, the Radix Paeoniae Alba 10 parts, 10 parts, Radix Rehmanniae Preparata, Radix Et Rhizoma Rhei 6 parts, Rhizoma Paridis 10 parts, Rhizoma Corydalis 10 parts, pollen 10 parts, Jiang Nanxing 10 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10 parts, Herba Scutellariae Barbatae 15 parts, Herba Taraxaci 15 parts, Flos Inulae 10 parts, 10 parts, Poria, the Rhizoma Atractylodis Macrocephalae 10 parts, 6 parts, Radix Glycyrrhizae, Pericarpium Citri Reticulatae 6 parts, Rhizoma Polygonati 10 parts, Fructus Amomi Rotundus 6 parts, Fructus Amomi 6 parts, Hirudo 6 parts, Fructus Mume 10 parts, Myrrha 10 parts, Cortex Magnoliae Officinalis 10 parts, Endothelium Corneum Gigeriae Galli 10 parts.
5. preparation method according to claim 3, is characterized in that, during described concentrated solution 80 DEG C, relative density is 1.15-1.30.
6. preparation method according to claim 3, is characterized in that, adding ethanol to ethanol content in described concentrated solution is 60%.
7. preparation method according to claim 3, is characterized in that, described adjust ph is to 5.0-7.0.
8. preparation method according to claim 3, is characterized in that, described sterilizing methods is 100 DEG C of sterilizing 30min.
9. preparation method according to claim 3, is characterized in that, each amount of water of described decoction is 6.5-8.5 times of medical material cumulative volume, and each decocting time is 50min.
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| CN107569694A (en) * | 2017-09-15 | 2018-01-12 | 杨润 | A kind of dept. of radiology's tumor imaging agent and preparation method thereof |
| CN109091660A (en) * | 2018-10-30 | 2018-12-28 | 冯光成 | It is a kind of for treating the Chinese prescription of gastric cancer |
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Application publication date: 20151209 |