CN101773648A - Chinese medicine composition for treating gastric cancer and preparation method thereof - Google Patents
Chinese medicine composition for treating gastric cancer and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a Chinese medicine composition for treating gastric cancer and a preparation method thereof. The Chinese medicine composition is mainly formed by the following raw medicine materials: coix seed, Poria cocos, Mongolian snakegourd root, dried tangerine peel, rhizoma cyperi, elecampane, indigo naturalis, Vietnamese sophora root, lithospermum, rheum officinale, monkshood, medicated leaven, malt, peach kernel, safflower, rhizoma sparganii, zedoary, ground beetle, aspongopus, Rhizoma acori Graminei, pangolin scale, hematoxylon, leech, agilawood, dalbergia wood, storax and the like. The Chinese medicine composition of the invention can be prepared into any kind of common oral preparation according to the conventional Chinese medicine preparation method. The invention has the advantages that symptoms such as epigastrium discomfort or pain, pain aggravation after eating, frequent attack, pain spread to waist and back, anepithymia, fatigue and acratia, nausea and vomiting, burning stomach, sallow complexion, emaciation and the like are obviously improved, the clinical curative effect is exact, the curative effect is obvious, the rapid effect is obtained, the cost is low, basically no toxic side effect exists and the like.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of gastric cancer.Relating in particular to a kind of is the Chinese medicine composition and preparation method thereof of the treatment gastric cancer of crude drug with the Chinese herbal medicine.
Background technology
Gastric cancer is one of China's common malignancy, in the first place that its sickness rate of China occupies all kinds of tumors.Its pathogenic factor is not clear, can betide any age, can betide any position of stomach, common sympton is epigastric discomfort or epigastrium pain, and feed back symptom is often aggravated, and the pain increased along with disease progression, outbreak is frequent, and to the lower back radiation, together often with inappetence, lassitude and weak, nausea and vomiting, stomach is scorching hot, shallow complexion, symptoms such as emaciated physique.China has 170,000 people to die from gastric cancer every year approximately, almost near 1/4 of whole malignant tumor death tolls, and annually also has that new Patients with Gastric Cancer generates more than 20,000, is the healthy diseases of a kind of serious threat people.
Modern medicine adopts the Therapeutic Method of operation, chemotherapy, radiotherapy, its treatment side effect is big, the relapse and metastasis probability is very high, survival rate is low, in order to overcome above-mentioned defective, the present invention is based on the differential diagnosis of diseases and the dialectical principle that combines of Chinese traditional treatment gastric cancer, treating both the principal and secondary aspects of a disease, deficiency and excess is also controlled, inside and outside logical the accent, emergency is taken in concurrently, filters out depressed liver-energy dispersing and QI regulating, tonification healthy energy, dissipating phlegm and resolving masses, blood circulation promoting and blood stasis dispelling, Jiao Wen Huazhong, warming YANG analgesic natural plant, according to the theory of Chinese medical science prescription, be prepared from according to certain weight proportion.A kind of Chinese medicine composition of evident in efficacy, with low cost, treatment gastric cancer that toxic and side effects is minimum is provided.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage forms, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be: pill, capsule, tablet, powder, granule or oral liquid etc.
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Summary of the invention
Technical problem to be solved by this invention is assorted to overcome above-described shortcoming, and a kind of Chinese medicine composition of treatment of evident in efficacy, with low cost, almost non-toxic side effect is provided.
The technical problem of the desired solution of the present invention realizes by following technological approaches.
A kind of Chinese medicine composition for the treatment of gastric cancer of the present invention, the component of main following weight portion is formed:
1～150 part of Semen Coicis, 1～150 part in Poria, 1～100 part of Radix Trichosanthis, 1～150 part of Pericarpium Citri Reticulatae, 1～50 part of Fructus Gardeniae, 1～50 part of Rhizoma Coptidis, 1～100 part of Radix Sophorae Flavescentis, 1～50 part of Herba Taraxaci, 1～50 part of Herba Andrographis, 1～50 part of Indigo Naturalis, 1～100 part of Radix Sophorae Tonkinensis, 1～50 part of Radix Arnebiae (Radix Lithospermi), 1～50 part of Radix Et Rhizoma Rhei, 1～150 part of Massa Medicata Fermentata, 1～100 part in Fructus Hordei Germinatus, 1～100 part of Fructus Setariae Germinatus, 1～50 part in Semen Persicae, 1～50 part on Flos Carthami, 1～50 part of rhizoma sparganic, 1～50 part of Rhizoma Curcumae, 1～50 part of Olibanum (processed), 1～50 part of Myrrha (processed), 1～50 part of Pyritum, 1～50 part of Eupolyphaga Seu Steleophaga, 1～50 part of Squama Manis, 1～100 part of Rhizoma Acori Graminei, 1～100 part of Styrax, 1～100 part of Benzoinum, 1～100 part of Herba Lysimachiae foenum-graeci, 1～50 part of Rhizoma Chuanxiong, 1～50 part of Lignum Aquilariae Resinatum, 1～100 part of Lignum Dalbergiae Odoriferae, 1～150 part of Radix Astragali, 1～100 part of Radix Codonopsis, 1～150 part of the Radix Paeoniae Alba, 1～50 part of Aspongopus, 1～50 part of Eupolyphaga Seu Steleophaga, 1～120 part of Rhizoma Cyperi, 1～50 part of the Radix Aucklandiae.
Be preferably:
100 parts of Semen Coiciss, 50 parts in Poria, 20 parts of Radix Trichosanthis, 50 parts of Pericarpium Citri Reticulataes, 15 parts of Fructus Gardeniaes, 15 parts of Rhizoma Coptidis, 30 parts of Radix Sophorae Flavescentiss, 20 parts of Herba Taraxaci, 20 parts of Herba Andrographis, 20 parts of Indigo Naturaliss, 30 parts of Radix Sophorae Tonkinensiss, 15 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Radix Et Rhizoma Rhei, 50 parts of Massa Medicata Fermentata, 30 parts in Fructus Hordei Germinatus, 20 parts of Fructus Setariae Germinatuss, 15 parts in Semen Persicae, 15 parts on Flos Carthami, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 10 parts of Olibanum (processed), 10 parts of Myrrha (processed)s, 15 parts of Pyritums, 15 parts of Eupolyphaga Seu Steleophagas, 15 parts of Squama Maniss, 30 parts of Rhizoma Acori Graminei, 20 parts of Styrax, 20 parts of Benzoinumes, 20 parts of Herba Lysimachiae foenum-graeci, 20 parts of Rhizoma Chuanxiongs, 10 parts of Lignum Aquilariae Resinatum, 15 parts of Lignum Dalbergiae Odoriferaes, 30 parts of Radix Astragali, 20 parts of Radix Codonopsis, 30 parts of the Radix Paeoniae Albas, 15 parts of Aspongopuss, 15 parts of Eupolyphaga Seu Steleophagas, 30 parts of Rhizoma Cyperis, 15 parts of the Radix Aucklandiae.
The weight portion consumption of each component of Chinese medicine composition of the present invention can also be:
1～50 part of Radix Aconiti, 1～50 part of Radix Stephaniae Tetrandrae, 1～50 part of Rhizoma Atractylodis, 1～100 part of Cortex Magnoliae Officinalis, 1～50 part of Ganoderma, 1～50 part of Semen Plantaginis, 1～30 part of Resina Ferulae, 1～50 part of Lignum Sappan, 1～50 part of Hirudo, 1～50 part of Tabanus, 1～50 part on Pericarpium Citri Reticulatae Viride, 1～50 part of Cortex Fraxini, 1～50 part of Fructus Amomi, 1～50 part of Fructus Tsaoko, 1～100 part of Flos Lonicerae, 1～50 part of Fructus Forsythiae, 1～100 part of Herba Violae, 1～50 part of the Rhizoma Atractylodis Macrocephalae, 1～100 part of Rhizoma Dioscoreae, 1～100 part of Herba Patriniae, 1～50 part of Herba Lobeliae Chinensis, 1～50 part of Semen Pruni, 1～100 part of Semen Vaccariae, 1～50 part of Flos Campsis.
Be preferably:
5 parts of Radix Aconitis, 15 parts of Radixs Stephaniae Tetrandrae, 20 parts of Rhizoma Atractylodis, 50 parts of Cortex Magnoliae Officinalis, 20 parts of Ganodermas, 20 parts of Semen Plantaginiss, 10 parts of Resina Ferulaes, 20 parts of Lignum Sappans, 15 parts of Hirudos, 15 parts of Tabanuss, 15 parts on Pericarpium Citri Reticulatae Viride, 20 parts of Cortex Fraxinis, 15 parts of Fructus Amomis, 15 parts of Fructus Tsaokos, 20 parts of Flos Loniceraes, 15 parts of Fructus Forsythiaes, 20 parts of Herba Violaes, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Rhizoma Dioscoreaes, 15 parts of Herba Patriniae, 15 parts of Herba Lobeliae Chinensis, 15 parts of Semen Prunis, 20 parts of Semen Vaccariae, 15 parts of Flos Campsiss.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage form, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be pill, capsule, tablet, powder, granule or oral liquid etc.
Chinese medicine composition of the present invention is opened one's minds based on traditional Chinese medical science the five internal organs differentiation of syndromes of YIN and YANG guiding principle, in conjunction with safe one and Pu innovation theory system " ten thousand diseases ascent theory ", " the five internal organs differentiation of syndromes of YIN and YANG guiding principle ", " three-dimensional conservation regulation and control rule " and clinical treatment " pairing principle " are as instructing, take place in conjunction with disease, development and the rule that changes, classify according to the original new drug system, formation is monarch with " the five internal organs basic function is adjusted; equilibrium between yin and yang coordination side ", " the main pathogenesis of the five internal organs adjustment side " is minister, " therapy of serious disease side " is assistant, " clinical fundamental symptoms symptomatic treatment side " Chinese medicine patent medicine " original new drug system " for making.
The used herbal raw material medicine of the present invention all can be buied from the Chinese medicine shop, and its specification meets national medical standard.
Usage and dosage: dosage of the present invention depends on concrete dosage form, factors such as patient age, body weight, health status.As guidance: for oral administration: 1) capsule: obey 2～5 every day three times at every turn, every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2～4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The treatment that the present invention is directed to patients with gastric cancer is very effective, various crude drug are coordinated mutually can play together and are at utmost brought into play drug effect, can effectively improve the self-coordination ability of patient's body, significantly improve function and clinical subjective symptoms, have advantage such as have no side effect, expense is lower in addition.
The specific embodiment
Further describe the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never are limited to the present invention.
The preparation of [embodiment 1] capsule
Take by weighing each raw material by following weight portion: 100 parts of Semen Coiciss, 50 parts in Poria, 20 parts of Radix Trichosanthis, 50 parts of Pericarpium Citri Reticulataes, 15 parts of Fructus Gardeniaes, 15 parts of Rhizoma Coptidis, 30 parts of Radix Sophorae Flavescentiss, 20 parts of Herba Andrographis, 20 parts of Indigo Naturaliss, 30 parts of Radix Sophorae Tonkinensiss, 15 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Radix Et Rhizoma Rhei, 50 parts of Massa Medicata Fermentata, 30 parts in Fructus Hordei Germinatus, 20 parts of Fructus Setariae Germinatuss, 15 parts in Semen Persicae, 15 parts on Flos Carthami, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 10 parts of Olibanum (processed), 10 parts of Myrrha (processed)s, 15 parts of Pyritums, 15 parts of Eupolyphaga Seu Steleophagas, 15 parts of Squama Maniss, 30 parts of Rhizoma Acori Graminei, 30 parts of Radix Astragali, 20 parts of Radix Codonopsis, 30 parts of the Radix Paeoniae Albas, 15 parts of Aspongopuss, 15 parts of Eupolyphaga Seu Steleophagas, 50 parts of Cortex Magnoliae Officinalis, 20 parts of Ganodermas, 15 parts of Fructus Amomis, 30 parts of Rhizoma Dioscoreaes, 15 parts of Herba Patriniae, 15 parts of Herba Lobeliae Chinensis, 20 parts of Semen Vaccariae, 15 parts of Flos Campsiss.
Grind into after each component mixing with above-mentioned weight and incapsulate promptly after fine powder is crossed 1500 mesh sieves.
The preparation of [embodiment 2] granule
Take by weighing each raw material by following weight portion: 100 parts of Semen Coiciss, 50 parts in Poria, 20 parts of Radix Trichosanthis, 50 parts of Pericarpium Citri Reticulataes, 15 parts of Fructus Gardeniaes, 15 parts of Rhizoma Coptidis, 30 parts of Radix Sophorae Flavescentiss, 20 parts of Herba Andrographis, 20 parts of Indigo Naturaliss, 30 parts of Radix Sophorae Tonkinensiss, 15 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Radix Et Rhizoma Rhei, 50 parts of Massa Medicata Fermentata, 30 parts in Fructus Hordei Germinatus, 20 parts of Fructus Setariae Germinatuss, 15 parts in Semen Persicae, 15 parts on Flos Carthami, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 10 parts of Olibanum (processed), 10 parts of Myrrha (processed)s, 15 parts of Pyritums, 15 parts of Eupolyphaga Seu Steleophagas, 15 parts of Squama Maniss, 30 parts of Rhizoma Acori Graminei, 30 parts of Radix Astragali, 20 parts of Radix Codonopsis, 30 parts of the Radix Paeoniae Albas, 15 parts of Aspongopuss, 15 parts of Eupolyphaga Seu Steleophagas, 50 parts of Cortex Magnoliae Officinalis, 20 parts of Ganodermas, 15 parts of Fructus Amomis, 30 parts of Rhizoma Dioscoreaes, 15 parts of Herba Patriniae, 15 parts of Herba Lobeliae Chinensis, 20 parts of Semen Vaccariae, 15 parts of Flos Campsiss.
Each raw material of above-mentioned weight fraction is mixed, after grinding into fine powder and crossing 1500 mesh sieves, add ethanol and make adhesive, add starch and do filler, be pressed into granule.
The preparation of [embodiment 3] tablet
Take by weighing each raw material by following weight portion: 100 parts of Semen Coiciss, 50 parts in Poria, 20 parts of Radix Trichosanthis, 50 parts of Pericarpium Citri Reticulataes, 15 parts of Fructus Gardeniaes, 15 parts of Rhizoma Coptidis, 30 parts of Radix Sophorae Flavescentiss, 20 parts of Herba Andrographis, 20 parts of Indigo Naturaliss, 30 parts of Radix Sophorae Tonkinensiss, 15 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Radix Et Rhizoma Rhei, 50 parts of Massa Medicata Fermentata, 30 parts in Fructus Hordei Germinatus, 20 parts of Fructus Setariae Germinatuss, 15 parts in Semen Persicae, 15 parts on Flos Carthami, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 10 parts of Olibanum (processed), 10 parts of Myrrha (processed)s, 15 parts of Pyritums, 15 parts of Eupolyphaga Seu Steleophagas, 15 parts of Squama Maniss, 30 parts of Rhizoma Acori Graminei, 30 parts of Radix Astragali, 20 parts of Radix Codonopsis, 30 parts of the Radix Paeoniae Albas, 15 parts of Aspongopuss, 15 parts of Eupolyphaga Seu Steleophagas, 50 parts of Cortex Magnoliae Officinalis, 20 parts of Ganodermas, 15 parts of Fructus Amomis, 30 parts of Rhizoma Dioscoreaes, 15 parts of Herba Patriniae, 15 parts of Herba Lobeliae Chinensis, 20 parts of Semen Vaccariae, 15 parts of Flos Campsiss.
Each raw material of above-mentioned weight portion is mixed, after grinding into fine powder and crossing 800～1200 order dusting covers, make tablet promptly.
The preparation of [embodiment 4] pill
Take by weighing each raw material by following weight portion: 100 parts of Semen Coiciss, 50 parts in Poria, 20 parts of Radix Trichosanthis, 50 parts of Pericarpium Citri Reticulataes, 15 parts of Fructus Gardeniaes, 15 parts of Rhizoma Coptidis, 30 parts of Radix Sophorae Flavescentiss, 20 parts of Herba Andrographis, 20 parts of Indigo Naturaliss, 30 parts of Radix Sophorae Tonkinensiss, 15 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Radix Et Rhizoma Rhei, 50 parts of Massa Medicata Fermentata, 30 parts in Fructus Hordei Germinatus, 20 parts of Fructus Setariae Germinatuss, 15 parts in Semen Persicae, 15 parts on Flos Carthami, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 10 parts of Olibanum (processed), 10 parts of Myrrha (processed)s, 15 parts of Pyritums, 15 parts of Eupolyphaga Seu Steleophagas, 15 parts of Squama Maniss, 30 parts of Rhizoma Acori Graminei, 30 parts of Radix Astragali, 20 parts of Radix Codonopsis, 30 parts of the Radix Paeoniae Albas, 15 parts of Aspongopuss, 15 parts of Eupolyphaga Seu Steleophagas, 50 parts of Cortex Magnoliae Officinalis, 20 parts of Ganodermas, 15 parts of Fructus Amomis, 30 parts of Rhizoma Dioscoreaes, 15 parts of Herba Patriniae, 15 parts of Herba Lobeliae Chinensis, 20 parts of Semen Vaccariae, 15 parts of Flos Campsiss.
Each raw material of above-mentioned weight is mixed, grind into cross 600～1000 mesh sieves behind the fine powder after, make pill promptly.
The preparation of [embodiment 5] oral liquid
Take by weighing each raw material by following weight portion: 100 parts of Semen Coiciss, 50 parts in Poria, 20 parts of Radix Trichosanthis, 50 parts of Pericarpium Citri Reticulataes, 15 parts of Fructus Gardeniaes, 15 parts of Rhizoma Coptidis, 30 parts of Radix Sophorae Flavescentiss, 20 parts of Herba Andrographis, 20 parts of Indigo Naturaliss, 30 parts of Radix Sophorae Tonkinensiss, 15 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Radix Et Rhizoma Rhei, 50 parts of Massa Medicata Fermentata, 30 parts in Fructus Hordei Germinatus, 20 parts of Fructus Setariae Germinatuss, 15 parts in Semen Persicae, 15 parts on Flos Carthami, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 10 parts of Olibanum (processed), 10 parts of Myrrha (processed)s, 15 parts of Pyritums, 15 parts of Eupolyphaga Seu Steleophagas, 15 parts of Squama Maniss, 30 parts of Rhizoma Acori Graminei, 30 parts of Radix Astragali, 20 parts of Radix Codonopsis, 30 parts of the Radix Paeoniae Albas, 15 parts of Aspongopuss, 15 parts of Eupolyphaga Seu Steleophagas, 50 parts of Cortex Magnoliae Officinalis, 20 parts of Ganodermas, 15 parts of Fructus Amomis, 30 parts of Rhizoma Dioscoreaes, 15 parts of Herba Patriniae, 15 parts of Herba Lobeliae Chinensis, 20 parts of Semen Vaccariae, 15 parts of Flos Campsiss.
Each raw material of above-mentioned weight is mixed, after three decoctions, three filtrates are mixed, filter, be concentrated into rule
Fixed concentration, put cold, the stock solution embedding, irradiation sterilization, after the check, packed products is made oral liquid promptly.
The clinical observation on the therapeutic effect experiment of [experimental example] traditional Chinese medicine composition for treating patients with gastric cancer of the present invention
One, the physical data of experimental subject: adopt Chinese medicine composition of the present invention to treat 278 routine patients altogether, wherein male 165 examples, women 113 examples; The oldest person 78 years old, the age reckling has only 34 years old.
Two, Therapeutic Method:
Usage and dosage: adopt the prepared medicament of the embodiment of the invention, its usage and consumption are as follows: 1) capsule: obey 2～5 every day three times at every turn, and every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2～4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The course of treatment: one month is a course of treatment, treats for 18 courses of treatment altogether.
Three, therapeutic evaluation standard
Cure: sign and symptom are improved fully, foci disappearance or basic the disappearance, and diet, stool are normal, and weight increase is in high spirits.
Produce effects: sign and symptom are significantly improved, and focus disappears substantially or significantly improves, and diet, stool are normal, weight increase, and spirit is fine.
Effectively: sign and symptom change, and focus has improvement, and diet, stool are normal substantially, weight increase, and random thoughts have discomfort slightly, but can accept.
Invalid: sign does not have change, symptom such as preceding, and focus development or transfer worsen.
Four, model case:
1, fourth so-and-so, man, 48 years old, engineer.
The postoperative gastric cancer moon is surplus, the face misery, two are dull few refreshing, emaciated physique, the food of receiving is down difficult, feel sick again and again, distension and fullness in the abdomen, pain unbearably, constipation, oliguria, red tongue becomes silted up, tongue is foul thick greasy, thready and rolling pulse.The palpation supraclavicular lymph nodes does not reach, and the vertical shape operative scar healing of upper abdomen is good, abdominal part flatulence feeling of fullness.
Took Chinese medicine composition of the present invention 15, a large amount of dirty things of stool diarrhea, stench is unusual, and abdominal distention is alleviated immediately, and stomachache alleviates, and greasy fur gradually moves back.Took Chinese medicine composition of the present invention again 1 month, complexion is gentle, and two have god, and abdominal pain and distension removes, and the food of receiving is unobstructed, and two is just normal.Continue and obeyed Chinese medicine composition of the present invention 3 months, diet is normal, weight increase, and spirit is gradually shaken, and symptom is greatly taken on a new look.The clothes Chinese medicine composition of the present invention 1 year that continues is surplus, and patient's body is sturdy, and the food of receiving has flavor, red tongue with thin fur, the normal worker of energy, meal is taken the photograph the sheet inspection and is shown that gastrointestinal anastomosis passes through smoothly, and the body of stomach wriggling is fair, not filling of gastric antrum portion barium agent, follow up a case by regular visits to so far, patient's body strong as before, healthy so far existence is more than 10 years.
2, Ke, man, 44 years old, manager.
The patient finds in the art that because of the lesser gastric curvature ulcer capable operative treatment that cancerates cancer extensively shifts, and only row is appeased excision.Postoperative abdominal flatulence, dysuria, spirit is not propped up, and arteries and veins is soft unable, blood pressure drops, dirty and greasy fur band Huang.
Took Chinese medicine composition of the present invention 3, abdominal distention alleviates, free movement of the bowels, and urine is also sharp, and spirit takes a turn for the better, and tongue fur is cleaner.Took Chinese medicine composition of the present invention again 1 month, abdominal distention is removed, and spirit is gradually shaken.Continue and obeyed Chinese medicine composition of the present invention 3 months, symptom disappears substantially, 2.5 kilograms of weight increase.The clothes Chinese medicine composition of the present invention 1 year that continues is surplus, makes regular check on no abnormality seen, follows up a case by regular visits to, and overall health of patients is good, controls back survival 16 years.
3, Wu, man, 71 years old, retired cadre.
The patient in certain hospital's row laparotomy exploration, sees that lesser gastric curvature and pars cardiaca have 8 * 7CM ulcer type lump because of upper gastrointestinal hemorrhage in the art, fix with the posterior wall of abdomen adhesion, and the extensive swelling of stomach peripheral lymph node, fixing can't be excised, and pathology shows: tubular-type adenocarcinoma.The main suit: vague epigastralgia, xerostomia, the difficult row of defecating, the food of receiving is not good, red tongue white and thin fur, thready and weak pulse.
Took Chinese medicine composition of the present invention 15, vague epigastralgia and xerostomia all take a favorable turn, body of the tongue by red transfer to light red.Took Chinese medicine composition of the present invention again 1 month, spiritual amelioration, the food of receiving takes a turn for the better, and stool is normal, and every day 1 time, check: lump is more preceding obviously to be reduced.Continue and obeyed Chinese medicine composition of the present invention 3 months, symptom is greatly alleviated, check: lump 3 * 4CM.The clothes Chinese medicine composition of the present invention 1 year that continues is surplus, and lump disappears substantially, and it is as usual to live.
4, relative so-and-so, woman, 58 years old, retired worker.
The patient began before 1 year, does during stomachache, and gradually aggravation of back stomachache, body is day by day become thin, black stool, dizziness and blurred vision.Gastrointestinal is taken the photograph sheet and is all pointed out: " the stomach prepyloric region has the about 0.5 * 0.5cm size of little niche ", do not imitate through medical treatment.Back row laparotomy ventrotomy is detected: " find extensively adhesion, about 8 * 6 * 4cm of body of stomach rear wall lump such as stomach and peritoneum, liver, omentum majus, colon in the art, soak into whole coat of the stomach, the petechia is arranged; with the pancreas adhesion, the curved equal enlargement of lymph node of stomach size, matter is hard; be diagnosed as: gastric cancer, cancerous protuberance has transfer.Examine the main suit: epigastrium is vexed to expand, anorexia, and the vomiting yellow fluid, middle epigastrium can be touched lump, but slight ascites, the little string of pulse condition, thin white fur of tongue are owed clearly in the border.
Took Chinese medicine composition of the present invention 1 month, conscious epigastrium distending pain subtracts greatly, and stomach is received and slightly increased, and the vomiting idol is done, and urine is increased.Took Chinese medicine composition of the present invention again 1 month, abdominal distention, poor appetite, epigastrium have the lump protuberance, stool day row 4-5 time.The clothes Chinese medicine composition of the present invention 3 months that continues, behind the medicine abdominal distention alleviate, stomach receive gradually multiple, stool day row 1 time, epigastrium is not laid one's hand on and lump and ascites.The clothes Chinese medicine composition of the present invention 1 year that continues is surplus, and all diseases disappear, and repeatedly gastrointestinal is taken the photograph sheet and be there is no recurrence sign, and the ultrasound investigation liver is not visited and occupy-place focus and abdominal mass, and the whole body situation is good, and the housework of working hard work, treatment 28 years so far are still alive.
5, Liu, woman, 38 years old, peasant.
Patient's epigastrium pain discomfort is made gastroscope in local hospital and is shown " gastric cancer " for many years, row " radical operation for carcinoma of stomach ", and postoperative pathology: ulcer type adenocarcinoma (gastric antrum portion), little curved 6/9, curved greatly 3/4, under the pylorus 2/2,3/3 shifts on the pylorus.Done after leaving hospital 2 the course of treatment chemotherapy, because of side effect is too big, stop chemotherapy.Patient's appetite is relatively poor, lassitude and weak, and nausea and vomiting, stomach is scorching hot, shallow complexion, emaciated physique.
Took Chinese medicine composition of the present invention 1 month, nausea and vomiting alleviates, and surplus disease is gradually slow.Took Chinese medicine composition of the present invention again 2 months, nausea and vomiting ends, and stomach is scorching hot to be subtracted greatly, and appetite increases, and spirit is gradually shaken.The clothes Chinese medicine composition of the present invention 1 year that continues is surplus, and body constitution is recovered gradually, and all shapes such as ordinary person participate in farm work as usual, liver and gall and Abdominal B type ultrasonography, and the result shows: no abnormal discovery, no relapse and metastasis sign.
6, Huang, woman, 52 years old, teacher.
The patient felt stomach discomfort deeply before February, with paroxysmal pain, and abdominal distention and pain, diet is not advised, and poor appetite is become thin.Be diagnosed as gastric cancer through the CT of hospital, B ultrasonic, the flat lump of 3 * 4.5CM has been performed the operation and has been cut 1/3 focus, and chemicotherapy does not have improvement, and hopeless the leaving hospital in back goes home.
Took Chinese medicine composition of the present invention 1 month, all diseases alleviate.Took Chinese medicine composition of the present invention again 3 months, stomach discomfort alleviates, and paroxysmal pain disappears, and receives to increase.The clothes Chinese medicine composition of the present invention 1 year that continues is surplus, does not find cancerometastasis sign, and ordinary circumstance is good, no significant discomfort, and it is as usual to live, and feasible general physical work shows the patient and is still following up a case by regular visits to.
7, Zhao, man, 72 years old, peasant.
The patient began feed before February have sense of obstruction, upper abdominal pain not to draw attention, and at local hospital medication treatment, curative effect is bad.In the recent period normal vomiting, abdominal distention, have a meal be difficult to swallow, general weakness.Be diagnosed as gastric cancer on inspection, consider that the patient is older, operation can not be born, and family members refuse operation.
Took Chinese medicine composition of the present invention 1 month, abdominal distention, vomiting obviously alleviate.Took Chinese medicine composition of the present invention again 1 month, the difficulty of swallowing is alleviated, and spirit takes a turn for the better.Continue and obeyed Chinese medicine composition of the present invention 3 months, vomiting, stomachache disappear substantially, and it is gradually normal to swallow.The clothes Chinese medicine composition of the present invention 1 year that continues is surplus, and the patient lives normally, keeps moderate exercise every day, and it is in high spirits to sleep, and situation is stablized.
8, permitted certain, woman, 58 years old, accounting.
Nausea and vomiting, acid regurgitation appearred in the patient before 1 year, Chinese herbal treatment, effect do not show, the nausea and vomiting sx, and epigastrium pain discomfort appears, go to see a doctor immediately,, be diagnosed as: gastric cancer through row B ultrasonic, fibergastroscopy, row " resection of gastric carcinoma ", postoperative carries out chemotherapy, stops chemotherapy because of tolerating chemotherapy side effect, the recuperation of going home of leaving hospital.Check before January, show through the row fibergastroscopy: gastric cancer recurrence, patient's nausea and vomiting is heavier, can't take food, physical weakness, become thin, anemia.
Take Chinese medicine composition of the present invention 15, and vomitted number of times gradually and reduce, can advance a small amount of liquid food.Took Chinese medicine composition of the present invention again 3 months, appetite takes a turn for the better to some extent, the nausea and vomiting sx, and Upper abdominal pain is alleviated.Continue and obeyed Chinese medicine composition of the present invention 6 months, the nausea and vomiting transference cure, appetite increases, weight increase, anemiaing correcting, the check gastroscope shows: side of body lump obviously dwindles, and the patient is full of confidence.Continue and obeyed Chinese medicine composition of the present invention 6 months, gastroscopy is shown: lump complete obiteration, weight in patients have increased by 10 kilograms, and be radiant with vigour, energetic, no any discomfort symptom.
Five, therapeutic outcome:
In the 278 routine cases of being accepted for medical treatment,, wherein cure 25 examples through treatment in 18 months, produce effects 139 examples, effective 75 examples, invalid 39 examples, total effective rate reaches 85%.The result shows that Chinese medicine composition of the present invention has extremely significant curative effect to the treatment patients with gastric cancer.
Claims (7)
1. Chinese medicine composition for the treatment of gastric cancer is characterized in that: mainly contain following bulk drugs and form:
1～150 part of Semen Coicis, 1～150 part in Poria, 1～100 part of Radix Trichosanthis, 1～150 part of Pericarpium Citri Reticulatae, 1～50 part of Fructus Gardeniae, 1～50 part of Rhizoma Coptidis, 1～100 part of Radix Sophorae Flavescentis, 1～50 part of Herba Taraxaci, 1～50 part of Herba Andrographis, 1～50 part of Indigo Naturalis, 1～100 part of Radix Sophorae Tonkinensis, 1～50 part of Radix Arnebiae (Radix Lithospermi), 1～50 part of Radix Et Rhizoma Rhei, 1～150 part of Massa Medicata Fermentata, 1～100 part in Fructus Hordei Germinatus, 1～100 part of Fructus Setariae Germinatus, 1～50 part in Semen Persicae, 1～50 part on Flos Carthami, 1～50 part of rhizoma sparganic, 1～50 part of Rhizoma Curcumae, 1～50 part of Olibanum (processed), 1～50 part of Myrrha (processed), 1～50 part of Pyritum, 1～50 part of Eupolyphaga Seu Steleophaga, 1～50 part of Squama Manis, 1～100 part of Rhizoma Acori Graminei, 1～100 part of Styrax, 1～100 part of Benzoinum, 1～100 part of Herba Lysimachiae foenum-graeci, 1～50 part of Rhizoma Chuanxiong, 1～50 part of Lignum Aquilariae Resinatum, 1～100 part of Lignum Dalbergiae Odoriferae, 1～150 part of Radix Astragali, 1～100 part of Radix Codonopsis, 1～150 part of the Radix Paeoniae Alba, 1～50 part of Aspongopus, 1～50 part of Eupolyphaga Seu Steleophaga, 1～120 part of Rhizoma Cyperi, 1～50 part of the Radix Aucklandiae.
2. according to the described Chinese medicine composition of claim 1, it is characterized in that: the weight portion of each crude drug is:
100 parts of Semen Coiciss, 50 parts in Poria, 20 parts of Radix Trichosanthis, 50 parts of Pericarpium Citri Reticulataes, 15 parts of Fructus Gardeniaes, 15 parts of Rhizoma Coptidis, 30 parts of Radix Sophorae Flavescentiss, 20 parts of Herba Taraxaci, 20 parts of Herba Andrographis, 20 parts of Indigo Naturaliss, 30 parts of Radix Sophorae Tonkinensiss, 15 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Radix Et Rhizoma Rhei, 50 parts of Massa Medicata Fermentata, 30 parts in Fructus Hordei Germinatus, 20 parts of Fructus Setariae Germinatuss, 15 parts in Semen Persicae, 15 parts on Flos Carthami, 15 parts of rhizoma sparganic, 15 parts of Rhizoma Curcumae, 10 parts of Olibanum (processed), 10 parts of Myrrha (processed)s, 15 parts of Pyritums, 15 parts of Eupolyphaga Seu Steleophagas, 15 parts of Squama Maniss, 30 parts of Rhizoma Acori Graminei, 20 parts of Styrax, 20 parts of Benzoinumes, 20 parts of Herba Lysimachiae foenum-graeci, 20 parts of Rhizoma Chuanxiongs, 10 parts of Lignum Aquilariae Resinatum, 15 parts of Lignum Dalbergiae Odoriferaes, 30 parts of Radix Astragali, 20 parts of Radix Codonopsis, 30 parts of the Radix Paeoniae Albas, 15 parts of Aspongopuss, 15 parts of Eupolyphaga Seu Steleophagas, 30 parts of Rhizoma Cyperis, 15 parts of the Radix Aucklandiae.
3. according to the described Chinese medicine composition of claim 1, wherein crude drug also has:
1～50 part of Radix Aconiti, 1～50 part of Radix Stephaniae Tetrandrae, 1～50 part of Rhizoma Atractylodis, 1～100 part of Cortex Magnoliae Officinalis, 1～50 part of Ganoderma, 1～50 part of Semen Plantaginis, 1～30 part of Resina Ferulae, 1～50 part of Lignum Sappan, 1～50 part of Hirudo, 1～50 part of Tabanus, 1～50 part on Pericarpium Citri Reticulatae Viride, 1～50 part of Cortex Fraxini, 1～50 part of Fructus Amomi, 1～50 part of Fructus Tsaoko, 1～100 part of Flos Lonicerae, 1～50 part of Fructus Forsythiae, 1～100 part of Herba Violae, 1～50 part of the Rhizoma Atractylodis Macrocephalae, 1～100 part of Rhizoma Dioscoreae, 1～100 part of Herba Patriniae, 1～50 part of Herba Lobeliae Chinensis, 1～50 part of Semen Pruni, 1～100 part of Semen Vaccariae, 1～50 part of Flos Campsis.
4. according to the described Chinese medicine composition of claim 3, wherein the weight portion of each component is:
5 parts of Radix Aconitis, 15 parts of Radixs Stephaniae Tetrandrae, 20 parts of Rhizoma Atractylodis, 50 parts of Cortex Magnoliae Officinalis, 20 parts of Ganodermas, 20 parts of Semen Plantaginiss, 10 parts of Resina Ferulaes, 20 parts of Lignum Sappans, 15 parts of Hirudos, 15 parts of Tabanuss, 15 parts on Pericarpium Citri Reticulatae Viride, 20 parts of Cortex Fraxinis, 15 parts of Fructus Amomis, 15 parts of Fructus Tsaokos, 20 parts of Flos Loniceraes, 15 parts of Fructus Forsythiaes, 20 parts of Herba Violaes, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 30 parts of Rhizoma Dioscoreaes, 15 parts of Herba Patriniae, 15 parts of Herba Lobeliae Chinensis, 15 parts of Semen Prunis, 20 parts of Semen Vaccariae, 15 parts of Flos Campsiss.
5. according to claim 1,2,3 or 4 described any Chinese medicine compositions, it is characterized in that: can be prepared into any oral formulations commonly used according to the method for Chinese medicinal of routine.
6. according to the described Chinese medicine composition of claim 5, it is characterized in that: described oral formulations is pill, capsule, tablet, powder, granule or oral liquid.
7. the application of the described any Chinese medicine composition of claim 1～6 in preparation treatment gastric cancer medicine.
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Cited By (6)
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| CN103536862A (en) * | 2013-11-06 | 2014-01-29 | 河北联合大学 | Compound traditional Chinese medicine preparation with effects of benefiting qi and activating blood circulation for preventing and treating gastric cancer, and preparation method thereof |
| CN103977356A (en) * | 2014-05-29 | 2014-08-13 | 李绍华 | Pharmaceutical composition for treating duodenal cancer and gastric cancer |
| CN104352515A (en) * | 2014-09-22 | 2015-02-18 | 新乡医学院 | Drug composition for treating gastric carcinoma and application thereof |
| CN105126012A (en) * | 2015-07-23 | 2015-12-09 | 申金玉 | Traditional Chinese medicinal preparation for treating gastric cancer and preparation method of traditional Chinese medicinal preparation |
| CN105288464A (en) * | 2015-10-24 | 2016-02-03 | 四川聚豪生物科技有限公司 | Traditional Chinese medicine composition for treating gastric cancer with syndrome of deficient cold of spleen and stomach and preparation method of traditional Chinese medicine composition for treating gastric cancer with syndrome of deficient cold of spleen and stomach |
| CN105853609A (en) * | 2016-06-19 | 2016-08-17 | 李京烨 | Pharmaceutical preparation for treating and preventing stomach cancer and application thereof |
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| CN103055217B (en) * | 2013-02-06 | 2014-03-19 | 崔合芳 | Medical composition for recovering gastrointestinal function after gastrectomy |
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| CN101352557A (en) * | 2007-07-23 | 2009-01-28 | 梁健 | Chinese medicine preparation for treating gastric cancer and preparation method thereof |
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| CN1903346A (en) * | 2006-08-01 | 2007-01-31 | 于世琴 | Traditional Chinese medicine for treating gastric carcinoma |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103536862A (en) * | 2013-11-06 | 2014-01-29 | 河北联合大学 | Compound traditional Chinese medicine preparation with effects of benefiting qi and activating blood circulation for preventing and treating gastric cancer, and preparation method thereof |
| CN103536862B (en) * | 2013-11-06 | 2015-04-22 | 河北联合大学 | Compound traditional Chinese medicine preparation with effects of benefiting qi and activating blood circulation for preventing and treating gastric cancer, and preparation method thereof |
| CN103977356A (en) * | 2014-05-29 | 2014-08-13 | 李绍华 | Pharmaceutical composition for treating duodenal cancer and gastric cancer |
| CN104352515A (en) * | 2014-09-22 | 2015-02-18 | 新乡医学院 | Drug composition for treating gastric carcinoma and application thereof |
| CN105126012A (en) * | 2015-07-23 | 2015-12-09 | 申金玉 | Traditional Chinese medicinal preparation for treating gastric cancer and preparation method of traditional Chinese medicinal preparation |
| CN105288464A (en) * | 2015-10-24 | 2016-02-03 | 四川聚豪生物科技有限公司 | Traditional Chinese medicine composition for treating gastric cancer with syndrome of deficient cold of spleen and stomach and preparation method of traditional Chinese medicine composition for treating gastric cancer with syndrome of deficient cold of spleen and stomach |
| CN105853609A (en) * | 2016-06-19 | 2016-08-17 | 李京烨 | Pharmaceutical preparation for treating and preventing stomach cancer and application thereof |
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