CN101884714B

CN101884714B - Chinese medicinal decoction for treating urticaria

Info

Publication number: CN101884714B
Application number: CN2010102188661A
Authority: CN
Inventors: 唐公恩
Original assignee: Individual
Current assignee: Individual
Priority date: 2010-07-02
Filing date: 2010-07-02
Publication date: 2011-08-10
Anticipated expiration: 2030-07-02
Also published as: CN101884714A

Abstract

The invention discloses Chinese medicinal decoction for treating urticaria. Aiming at the characteristic of pathogenesis of the urticaria, namely Chinese doctors believe that the urticaria is induced by deficiency of yin-blood and wind-pathogen due to emotional depression, liver stagnation in discomfort, stagnation of flow of qi, fire formation from stagnation and ambustion in yin-blood, the decoction is prepared from Chinese medicinal herbs such as lightyellow sophora root, red paeony root, tuber fleeceflower root, Leonurus heterophyllus, densefruit pittany root-bark, divaricate saposhnikovia root, common ducksmeat herb, Indian buead, cinnamomvine and liquorice root which have the effects of nourishing qi and yin, nourishing bolld and promoting blood circulation and dispelling wind and removing dampness through elaborate compatibility. Clinical tests prove that the decoction has the good treatment effect on patients who surfer from the urticaria, and has the advantages of convenient administration, no toxic or side effect, safety, reliability and low treatment cost.

Description

The urticarial Chinese medicine decoction of a kind of treatment

Technical field

The invention belongs to technical field of Chinese medicines, relate to a kind of Chinese medicine composition, relate in particular to the urticarial Chinese medicine decoction of a kind of treatment.

Background technology

Urticaria is a kind of common skin disease.Causing mucocutaneous blood vessel that temporary inflammatory hyperemia takes place by various factors oozes out with big quantity of fluid.Cause the infringement of local edema.It takes place rapidly and disappears, has play to itch.Fever, stomachache, diarrhoea or other General Symptomies can be arranged.Often cause falling ill by certain food, medicine, biological product, focal infection, Nervous and Mental Factors, celiosite, extraneous stimulations such as cold and hot.Skin lesion is normal to be taken place suddenly, is the welt that limitation redness or pale asphyxia differ in size, and boundary is clear, and form differs, and skin lesion is also with scratching and increase, increase.Conscious violent pruritus burning sensation.Skin lesion continues half an hour mostly to a few hours spontaneous regression, leaves no trace after disappearing, rise one after another sometimes, but repeated multiple times outbreak in a day.The position is indefinite, can general whole body or be confined to certain one, and mucosa also can be got involved sometimes, as the appetizing intestinal takes place, symptoms such as nauseating, vomiting, stomachache, diarrhoea can be arranged then.Then uncomfortable in chest when the larynx mucosa is invaded, asthma, dyspnea, severe patient can cause and suffocate and threat to life.Clinically, if long-term or short time large bolus injection or dexamethasone for oral administration, triamcinolone, prednisone isocortex parahormone Drug therapy also can cause complication such as obesity, hirsutism, acne, blood sugar increasing, hypertension, edema, the reduction of blood potassium, menoxenia, osteoporosis, aseptic necrosis of bone, gastric and duodenal ulcers.Also can cause certain infringement to kidney, as increase the weight of the renal glomerular disease albuminuria, increase the weight of glomerular sclerosis, easily cause kidney calcification or calculus, bring out or increase the weight of renal infectious diseases, cause low potassium nephropathy etc.Also can cause a series of substance metabolism disorders such as body sugar, protein, fat and Water-Electrolyte, destroy the defence system of body and suppress the immunoreation ability.The patient who has has also produced the dependency to hormone, influences therapeutic effect.It is poor that Chinese traditional treatment exists therapeutic effect again, and slow problem takes effect.

Summary of the invention

Purpose of the present invention is exactly at urticarial pathogenic characteristic, and promptly the traditional Chinese medical science thinks that primary disease is how unsuccessful by mood, and stagnation of liver-QI is not relaxed, and obstruction of QI is not smooth, strongly fragrant and fire-transformation, and the cloudy blood of burning causes deficiency of YIN-blood, is subjected to ailment said due to cold or exposure again and brings out.Select the Chinese herbal medicine of benefiting qi and nourishing yin, nourshing blood and promoting blood circulation, expelling wind and removing dampness for use,, make decoction through meticulous compatibility.

The objective of the invention is to be achieved through the following technical solutions, this is treated urticarial Chinese medicine decoction and is made by the Chinese medicine of following weight fraction: Radix Sophorae Flavescentis 4-7 branch, Radix Paeoniae Rubra 4-7 branch, Radix Polygoni Multiflori 5-9 branch, Herba Leonuri 5-9 branch, Cortex Dictamni 2-5 branch, Radix Saposhnikoviae 2-5 branch, Herba Spirodelae 3-7 branch, Poria 3-7 branch, Rhizoma Dioscoreae 7-13 branch, Radix Glycyrrhizae 7-13 branch.

This is treated urticarial Chinese medicine decoction and is made by the Chinese medicine of following optimum weight branch: Radix Sophorae Flavescentis 5 minutes, Radix Paeoniae Rubra 5 minutes, Radix Polygoni Multiflori 7 minutes, Herba Leonuri 7 minutes, Cortex Dictamni 4 minutes, Radix Saposhnikoviae 4 minutes, Herba Spirodelae 5 minutes, Poria 5 minutes, Rhizoma Dioscoreae 10 minutes, Radix Glycyrrhizae 10 minutes.

Preparation method: take by weighing above-mentioned raw material of Chinese medicine in proportion, cleaning is dried, and is ground into granule, soaks 1.5 hours, decocts with water twice then, adds the water of 9 times of amounts of crude drug for the first time, after intense fire is fried boiling, slow fire boiling 2-2.5 hour again, gets decocting liquid, filtration.Add for the second time the water of 7 times of amounts of crude drug, decocted 1-1.5 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 190ml, high temperature sterilize, packing is promptly.

Radix Sophorae Flavescentis, Cortex Dictamni heat clearing and damp drying in the side, dispelling wind for relieving itching; The Radix Paeoniae Rubra clearing away heat and cooling blood, eliminating stasis to stop pain; The Radix Polygoni Multiflori nourishing the blood and yin; Loosening bowel to relieve constipation; The Herba Leonuri promoting blood circulation to remove blood stasis, inducing diuresis to remove edema; The Poria inducing diuresis to remove edema; Radix Saposhnikoviae is delivered and dispels the wind, removing dampness to relieve pain; The Herba Spirodelae diaphoresis is dispeled the wind, the heat clearing away of row water; The Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, the Rhizoma Dioscoreae strengthening the spleen and tonifying the lung, the benefit of reinforcing the kidney is smart.

Beneficial effect of the present invention: through clinical trial, decoction of the present invention is effective to the urticaria patient treatment, and taking convenience has no side effect, and is safe and reliable, and the treatment cost is low.

Clinical data

1, physical data 120 routine patients are a precious case, are divided into two groups at random, and 60 examples are organized in treatment, male 35 examples, and women 25 examples, year makes 15-60 year; The course of disease 30 days-2.5 years.Matched group 60 examples, male 33 examples, women 27 examples; Year makes 16-60 year; The course of disease 40 days-3 years.Two groups make in year, sex, the equal no difference of science of statistics of the course of disease (＞0.05P), have comparability.

2, the inclusion criteria clinical manifestation meets the urticaria diagnostic criteria: cerise or pale asphyxia welt appear in skin, and size and form differs, and duration of seizure is indefinite, continue several minutes to a few hours or a couple of days, erythema leaves no trace after disappearing, companion's pruritus, and show effect repeatedly more than 6 weeks; Do not use antihistamine and glucocorticoids medicine in nearly 1 week; Get rid of pregnancy women and more serious cardiovascular disease, liver, kidney disease patient are arranged.

3, oral decoction of the present invention is organized in the Therapeutic Method treatment, and sooner or later respectively obey one bag every day; Matched group oral hydrochloride levocetirizine 5mg, once a day, two groups of equal medications one month.

4, curative effect determinate standard is with reference to " traditional Chinese medical science skin disease diagnosis criterion of therapeutical effect " in " People's Republic of China's Chinese medicine industry standard " of State Administration of Traditional Chinese Medicine's issue in 1994.Cure: welt disappears, and clinical sign disappears, and the person does not reaccess.Take a turn for the better: welt disappear 30% or the back recurrent interval time that disappears prolong sx persons such as pruritus.Do not heal: welt and pruritus do not have obvious improver, and less than 30% perhaps disappears.

5, therapeutic effect treatment group is cured 29 examples, 27 examples that take a turn for the better, 4 examples that do not heal, total effective rate 93.3%; Matched group is cured 26 examples, 23 examples that take a turn for the better, 11 examples that do not heal, total effective rate 81.7%; The treatment group obviously is better than matched group.

Treatment group patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

Embodiment takes by weighing Radix Sophorae Flavescentis 50g, Radix Paeoniae Rubra 50g, Radix Polygoni Multiflori 70g, Herba Leonuri 70g, Cortex Dictamni 40g, Radix Saposhnikoviae 40g, Herba Spirodelae 50g, Poria 50g, Rhizoma Dioscoreae 100g, Radix Glycyrrhizae 100g.With above-mentioned raw material of Chinese medicine, cleaning is dried, and is ground into granule, soaks 1.5 hours, decocts with water twice then, adds the water of 9 times of amounts of crude drug for the first time, and after intense fire was fried boiling, slow fire boiling was 2 hours again, gets decocting liquid, filtration.Add for the second time the water of 7 times of amounts of crude drug, decocted 1.5 hours, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 190ml, high temperature sterilize, packing is promptly.

Claims

1. the urticarial Chinese medicine decoction of treatment is characterized in that this treats urticarial Chinese medicine decoction and made by following parts by weight of Chinese traditional medicine: Radix Sophorae Flavescentis 4-7 part, Radix Paeoniae Rubra 4-7 part, Radix Polygoni Multiflori 5-9 part, Herba Leonuri 5-9 part, Cortex Dictamni 2-5 part, Radix Saposhnikoviae 2-5 part, Herba Spirodelae 3-7 part, Poria 3-7 part, Rhizoma Dioscoreae 7-13 part, Radix Glycyrrhizae 7-13 part.

2. the urticarial Chinese medicine decoction of a kind of treatment according to claim 1 is characterized in that this treats urticarial Chinese medicine decoction and made by the Chinese medicine of following optimum weight part: 5 parts of Radix Sophorae Flavescentiss, 5 parts of Radix Paeoniae Rubra, 7 parts of Radix Polygoni Multiflori, 7 parts of Herba Leonuris, 4 parts of Cortex Dictamni, 4 parts of Radix Saposhnikoviaes, 5 parts in Herba Spirodelae, 5 parts in Poria, 10 parts of Rhizoma Dioscoreaes, 10 parts in Radix Glycyrrhizae.