CN102228560A

CN102228560A - Medicine for treating chronic pharyngitis

Info

Publication number: CN102228560A
Application number: CN2011101368820A
Authority: CN
Inventors: 丁见; 李学风
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-05-25
Filing date: 2011-05-25
Publication date: 2011-11-02
Anticipated expiration: 2031-05-25
Also published as: CN102228560B

Abstract

The invention discloses a medicine for treating chronic pharyngitis. The medicine is characterized in that: the medicine is prepared from the raw materials of, by weight: 12 parts of seaweed, 12 parts of kelp, 16 parts of oyster, 13 parts of clam shell, 15 parts of prunella vulgaris, 15 parts of dandelion, 12 parts of cynanchi root, 10 parts of cortex lycii, 10 parts of radix scrophulariae, 15 parts of wild dendranthema flower, and 15 parts of periostracum cicadae. The medicine can be any oral preparation acceptable in pharmaceutics. The medicine for treating chronic pharyngitis is prepared according to Chinese medical scientific theories and clinic treatment experiences. According to the invention, hardness softening and bind dissipating Chinese medicine materials are adopted as main materials, and heat clearing and detoxifying Chinese medicine materials are adopted as blended in. The Chinese medicine can be prepared into a modern form of instant medicinal granules. According to clinic test results, with the medicine, pharyngeal lumps of chronic pharyngitis patients can be softened, patient stasis can be dissipated, and inflammatory exudation and tissue hyperplasia can be inhibited. With efficacies of hardness softening, bind dissipating, heat clearing and detoxifying, the medicine has relatively ideal curative effect against chronic pharyngitis.

Description

A kind of medicine for the treatment of chronic pharyngitis

Technical field

The present invention relates to a kind of medicine for the treatment of pharyngitis, particularly a kind of Chinese medicine composition for the treatment of chronic pharyngitis.

Background technology

Pharyngitis, especially chronic pharyngitis are clinical frequently-occurring disease, commonly encountered diseases.Treat this sick Chinese patent medicine at present; the XILEI SAN that adopt " compendium on epidemic febrile disease " more; the BINGPENG SAN of " Waike Zhengzong, Orthodox Manual of External Diseases "; LIUSHEN WAN on the Lei Yun; the pills for throat disease of " the basic Chinese patent medicine of China ", Fructus Canarii ball, Pulvis Indigo Naturalis are through the TIEDI WAN of proved recipe; the Calculus Bovis holding in the mouth for dissolving drug ball of " national Chinese medicine patent medicine formulary ", the cow-bezoar anti-toxic bolus of " pharmacopeia " etc.But above-mentioned Chinese patent medicine; polygamy has Calculus Bovis, Moschus, Venenum Bufonis, Margarita, Cinnabaris, Borneolum Syntheticum etc. with heat-clearing and toxic substances removing, and the corruption of healing of saturating flesh is main, to treating acute pharyngitis curative effect is preferably arranged through clinical this type of Chinese patent medicine of checking that waits; but for treatment chronic pharyngolaryngitis disease, curative effect is not satisfactory.Trace it to its cause, above-mentioned Chinese patent medicine has mostly been ignored the existence of these organic disease assertive evidences of the many nodosities of throat vocal cords, looses thoroughly so only bias toward heat clearing away when prescription, considers the eliminating stagnation softening the hard mass and give, so that all is should control in urgency, should not control in slowly.Therefore, be necessary especially to develop a kind of to treatment chronic pharyngitis specific Chinese Traditional Medicines.

Summary of the invention

Task of the present invention is to solve the existing defective of the Chinese Traditional Medicines that are used for the treatment of pharyngitis in the prior art, and a kind of medicine for the treatment of chronic pharyngitis is provided.

Its technical solution is:

A kind of medicine for the treatment of chronic pharyngitis, the medicament that it is prepared from by the following weight proportion raw material:

12 parts of Sargassums, 12 parts of Thallus Laminariae (Thallus Eckloniae)s, 16 parts of Concha Ostreaes, 13 parts of Concha Meretricis Seu Cyclinaes, 15 parts of Spica Prunellaes, 15 parts of Herba Taraxacis, 12 parts of Radix Cynanchi Atratis, 10 parts of Cortex Lycii, 10 parts of Radix Scrophulariaes, 15 parts of Flos Chrysanthemi Indicis, 15 parts of Periostracum Cicadaes.

Above-mentioned medicament is a said peroral dosage form on any pharmaceutics.

Above-mentioned medicament is a kind of granule, earlier with Concha Meretricis Seu Cyclinae in the above-mentioned raw material of Chinese medicine and Concha Ostreae, be ground into Chinese medicine powder, after 1 hour, add all the other raw material of Chinese medicine again with the decoction of cloth parcel, decoct with water secondary, each 2 hours, collecting decoction filtered in static 24 hours, after filtrate is condensed into relative density 1.10, add 75% ethanol and contain the alcohol amount to the filtrate and reach 60%, stir, left standstill 24 hours, filter once more, it is 1.25～1.3 thick paste that filtrate is condensed into relative density with ethanol, and meter is got 1 part of thick paste by weight ratio, with each 2.5 parts in Icing Sugar, dextrin, granulate, be drying to obtain finished product.

The present invention has following useful technique effect:

The medicine that the present invention treats chronic pharyngitis is according to Chinese medical theory and in conjunction with clinical treatment experience, and based on the raw material of Chinese medicine of hard masses softening and resolving, compatibility is with the raw material of Chinese medicine of heat-clearing and toxic substances removing, and can be processed into compound Chinese medicinal preparation by the modern formulation electuary.Can make through the present invention of clinical trial proof that the pharyngeal affected part of chronic pharyngitis patient lump is softening, the stasis of blood stagnates dissipates, suppress inflammatory exudation and hamartoplasia, have the effect of hard masses softening and resolving, heat-clearing and toxic substances removing, being used for the treatment of chronic pharyngitis has comparatively ideal curative effect.

The specific embodiment

A kind of medicine for the treatment of chronic pharyngitis, choose the following weight Chinese medicinal raw materials:

Sargassum 120 grams, Thallus Laminariae (Thallus Eckloniae) 120 grams, Concha Ostreae 160 grams, Concha Meretricis Seu Cyclinae 130 grams, Spica Prunellae 150 grams, Herba Taraxaci 150 grams, Radix Cynanchi Atrati 120 grams, Cortex Lycii 100 grams, Radix Scrophulariae 100 grams, Flos Chrysanthemi Indici 150 grams, Periostracum Cicadae 150 grams.

Earlier with Concha Meretricis Seu Cyclinae in the above-mentioned raw material of Chinese medicine and Concha Ostreae, be ground into Chinese medicine powder, wrap up decoction after 1 hour with cloth, add all the other raw material of Chinese medicine again, decoct with water secondary, each 2 hours, collecting decoction, filtered in static 24 hours, and after filtrate is condensed into relative density 1.10, added 75% ethanol and contain the alcohol amount to the filtrate and reach 60%, stir, left standstill 24 hours, and filtered once more, it is 1.25～1.3 thick paste that filtrate is condensed into relative density with ethanol, count by weight ratio, get 1 part of thick paste,, granulate, be drying to obtain finished product with each 2.5 parts in Icing Sugar, dextrin.The medicament that this example obtains is the granule in the peroral dosage form.

Above-mentioned finished product is a brown granular; Sweet, little hardship of distinguishing the flavor of.

The specification of above-mentioned finished product, usage and consumption: above-mentioned finished product can be taked bag type package, every bag heavy 16g; Boiled water is taken after mixing it with water, one time 1 bag, 2～3 times on the one, continuous 21 days is a course of treatment.

Except that above-mentioned granule, pharmaceutical dosage form of the present invention can also be made said peroral dosage form on other any pharmaceutics.

In the above-mentioned embodiment, the Sargassum hardship is salty-cold, goes into liver stomach kidney channel, and hardship can be let out knot, salty energy softening the hard mass, but cold heat clearing away.So tool hard masses softening and resolving, the merit of heat clearing away expectorant, and the diuretic effect is arranged.All goiter scrofulas, diseases such as edema tuberosity are product commonly used; Thallus Laminariae (Thallus Eckloniae) effectiveness is identical with Sargassum and stronger, the two mutual reinforcement between, and the curative effect benefit increases, and what be hard masses softening and resolving will product, are to be principal agent; Concha Ostreae matter cold in nature is heavy, energy heat clearing away tonifying YIN, YANG hyperactivity suppressing calmness, salty then hard masses softening and resolving; Concha Meretricis seu Cyclinae is salty-cold goes into lung, can removing heat from the lung and dissipating phlegm, and hard masses softening and resolving, inducing diuresis to remove edema, with Sargassum, Thallus Laminariae (Thallus Eckloniae) mutually 5, benefit increases the merit of its change heavily fortified point.Be aided with other expectorant of invigorating blood circulation again, heat-clearing and toxic substances removing, medicine among the Shu Xuan complex tone can giving consideration to both the incidental and fundamental, and the treatment chronic pharyngitis is had comparatively ideal curative effect.

Chronic pharyngolaryngitis is more refractory commonly encountered diseases, frequently-occurring disease.The 90 routine patients that in the recent period used Drug therapy of the present invention have obtained comparatively satisfied curative effect, now specify as follows:

1. object and method:

1.1 physical data:

The object of observation is totally 90 examples, wherein male 38 examples, women 52 examples; 13～66 years old age, 40.3 years old mean age.Chronic pharyngitis 23 examples in 90 examples, chronic laryngitis 22 examples, chronic pharyngolaryngitis 20 examples, chronic pharyngolaryngitis accompanying sound band brief summary 25 examples.Have acute pharyngolaryngitis history of repeated attack person to account for 30% in the medical history, occupation accounts for 24.4% with the throat person, works under the dry air environment for a long time and thigmic stimulus gas and dust person account for 10%, 7.8%, 5.9% respectively.Many patients have the smoking hobby.

1.2 differentiation of symptoms and signs for classification of syndrome:

90 routine patients have carried out differentiation of symptoms and signs for classification of syndrome, are divided into YIN-deficiency type, qi-deficiency type, phlegm-heat type three types.

YIN-deficiency type: throat is done painful, and is scorching hot, and sx after the polylogia is choked and coughed no expectorant, or sticking on a small quantity expectorant, again and again ask drink, the drink amount is few, and symptom is obvious when reaching dusk in the afternoon, the congested kermesinus of bottleneck throat, mucosa drying, atrophy, or lymph foilicie hyperplasia is arranged, red tongue, thin fur is few, thready and rapid pulse.Totally 37 examples account for 41.1%.

Qi-deficiency type: dry laryngopharynx, but desire drink, cough has expectorant easily to cough up, fear of cold at ordinary times, easy catching a cold, refreshing tired unable, faint low voice or hoarse, big loose stool is thin, and check and see throat hyperemia not very, retropharyneal folliculosis, tongue fur is white and moist, thready and weak pulse, totally 42 examples account for 46.7%.

Phlegm-heat type: have sore throat, scorching hot, drying, diseases such as foreign body sensation are increased the weight of after the polylogia because of suffering from cold fatigue, cough, thick sputum, thirst and liking drink is checked and is seen that pharyngolaryngeal mucosa hyperemia is peony, plumpness, rear wall lymph follicle and funiculus lateralis enlargement, there is yellow-white secretions to adhere to, red tongue, greasy fur, rolling pulse.Totally 11 examples account for 12.2%.

1.3 method:

Take medicine of the present invention, every bag of 16g, three times on the one, each one bag, boiled water is taken after mixing it with water, and 3 weeks were a course of treatment.Beginning the back course of treatment checked once weekly in 1～4 week.

1.4 criterion of therapeutical effect:

Curative effect is main according to the remission degree, and produce effects is the whole or above transference cure of binomial of symptom, no side reaction; Effectively for there being one to disappear or improvement no side reaction in the symptom; Invalid is that symptom does not have to disappear or take a turn for the better.

2. result

2.1 curative effect:

90 routine patients are produce effects person's 14 examples after treating, and account for 15.6%; Responder's 58 examples account for 64.4%; Nonresponder's 18 examples account for 20%.Total effective rate is 80%.

25 routine vocal nodule persons, 16 routine vocal nodulees have in various degree and dwindle after treating.

2.2 doing well,improving situation:

Treatment back Most patients symptom has improvement in various degree, serves as obvious to improve irritable cough, fatigue of voice, pharyngeal sticking expectorant sense, laryngalgia, hoarseness symptom all wherein.

2.3 sign is improved situation:

After treatment, 64% patient's vocal nodule is dwindled with the vocal nodule patient, and vocal cords edema, vocal cords closure are bad, the larynx mucous hyperemia all improves significantly.

2.4 toxic and side effects:

Remove 1 example diarrhoea in the therapeutic process, outside the 1 routine constipation, do not have other side effect.

Verified that medicine of the present invention has heat-clearing and toxic substances removing, the effect of hard masses softening and resolving through clinical principium; Be a kind of more satisfactory Chinese Traditional Medicines that are used for the treatment of chronic pharyngitis.

Claims

1. medicine for the treatment of chronic pharyngitis is characterized in that: the medicament that it is prepared from by the following weight proportion raw material:

2. the medicine of treatment chronic pharyngitis according to claim 1 is characterized in that: described medicament is a said peroral dosage form on any pharmaceutics.

3. the medicine of treatment chronic pharyngitis according to claim 2, it is characterized in that: described medicament is a kind of granule, earlier with Concha Meretricis Seu Cyclinae in the above-mentioned raw material of Chinese medicine and Concha Ostreae, is ground into Chinese medicine powder, wrap up decoction after 1 hour with cloth, add all the other raw material of Chinese medicine again, decoct with water secondary, each 2 hours, collecting decoction, filtered in static 24 hours, and after filtrate is condensed into relative density 1.10, added 75% ethanol and contain the alcohol amount to the filtrate and reach 60%, stir, left standstill 24 hours, and filtered once more, it is 1.25～1.3 thick paste that filtrate is condensed into relative density with ethanol, count by weight ratio, get 1 part of thick paste, with Icing Sugar, each 2.5 parts in dextrin is granulated, be drying to obtain finished product.