CN101607001B - Throat tablet for moisturizing and removing heat - Google Patents

Abstract

The invention relates to a throat tablet for moisturizing and removing heat, which aims to prevent and treat throat diseases. The throat tablet adopts the technical scheme that the throat tablet is prepared by the following components by weight: figwort of 230 to 250 g, burdock of 150 to 170 g, Chinese white olive of 150 to 170 g, balloon flower root of 150 to 170 g, red peony root of 150 to 170 g, kudzuvine root of 150 to 170 g, dried rehmannia root of 70 to 90 g, momordica grosvenori of 220 to 260 g and liquorice of 110 to 130. The preparing method of the throat tablet comprises the following steps: mixing the components together, adding 8 to 10 times of water weighter than total mendicant weight each time and boiling for 1.5 to 2 hours per time for two times, merging boiling solution obtained at two times, filtering, depressing and concentrating filtrate to 60 DEG C, determining cream with the relative density of 1.23 to 1.25; vacuumizing and drying at the vacuum degree of 0.06 to 0.08 Mpa and the temperature of 70 to 80 DEG C, and comminuting into fine powder; and finally pressing into the tablet. The invention has the advantages of scientific prescription compatibility, reasonable dosage, easy taking, low cost and good effect, is the innovation in the medicament of preventing and treating throat diseases, and has remarkable economic and social benefit.

Description

Throat tablet for moisturizing and removing heat

One, technical field

The present invention relates to medicine, particularly a kind of throat tablet for moisturizing and removing heat.

Two, background technology

People's bottleneck throat disease is a common frdquently encountered disease, as pharyngitis, laryngitis etc., pharynx, laryngitis is the bottleneck throat mucosa, submucous tissue and lymphoid tissue are anxious, chronic inflammatory disease, chronic pharyngolaryngitis particularly, be difficult to for a long time cure, life for people, working and learning and normal productive labor bring influence in various degree, healthy totally unfavorable to the people, therefore, people are studying how to prevent and treat the bottleneck throat disease always, particularly prevent and treat pharyngolaryngitis, the medicine that is used to prevent and treat pharyngolaryngitis at present is a lot, as various mouthfuls of food YANHOU PIAN, the siren throat lozenge, LIUSHEN WAN, detoxifying pills, gentamycin, Chinese and western drugses such as dexamethasone, but for various reasons, its prevention effect of these medicines can not be satisfactory, and people have been sought after taking convenience, effective, the novel drugs that price is low.

Three, summary of the invention

At above-mentioned situation, for overcoming the defective of prior art, the present invention's purpose just provides a kind of throat tablet for moisturizing and removing heat, can effectively solve the problem of preventing and treating of bottleneck throat disease, the technical scheme of its solution is, according to the Chinese medicine and pharmacy principle, the bottleneck throat disease, belong to the arthromyodynia scope as pharyngolaryngitis, its pathogenic factor is many-sided, mainly be except that pathogen (virus+antibacterial) goes into to soak, bad living habit and hobby, excessive as tobacco and wine, pungent irritable food, harmful gas, high temperature, cold, moist, dust atmosphere, overtired also is major incentive, but no matter be which kind of reason, finally be to cause QI and blood not lived, the bottleneck throat stasis of blood is long-pending and cause bottleneck throat discomfort or mucous hyperemia, swelling, the redness at vocal cords edge etc., therefore, control should be adopted blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, cough-relieving is a principle, so technical solution of the present invention adopts by the weight meter: Radix Scrophulariae 230-250g, Fructus Arctii 150-170g, Fructus Canarii 150-170g, Radix Platycodonis 150-170g, Radix Paeoniae Rubra 150-170g, Radix Puerariae 150-170g, Radix Rehmanniae 70-90g, Fructus Momordicae 220-260g and Radix Glycyrrhizae 110-130g make, wherein, above-mentioned each component is mixed, add medicine gross weight 8-10 water doubly at every turn, decoct 2 times, each 1.5-2 time hour, merge decoction liquor twice, filter, measuring relative density when filtrate decompression is concentrated into 60 ℃ is the clear paste of 1.23-1.25, again at vacuum 0.06-0.08Mpa, temperature 70-80 ℃ of following vacuum drying is ground into fine powder to doing, add appropriate amount of auxiliary materials, granulate drying, granulate, compacting in flakes, prescription compatibility science of the present invention, consumption is reasonable, easily takes, cost is low, effective, be the innovation on the control bottleneck throat disease medicament, economic and social benefit is remarkable.

Four, the specific embodiment

Below in conjunction with embodiment the specific embodiment of the present invention is elaborated.

Embodiment 1

The present invention in the specific implementation, can be by the weight meter: Radix Scrophulariae 240g, Fructus Arctii 160g, Fructus Canarii 160g, Radix Platycodonis 160g, Radix Paeoniae Rubra 160g, Radix Puerariae 160g, Radix Rehmanniae 80g, Fructus Momordicae 240g and Radix Glycyrrhizae 120g make, wherein said components is mixed, decoct 2 times, add the water of 10 times of amounts of component gross weight 1480g the 1st time, decocted 2 hours, add the water of 8 times of amounts of component gross weight 1480g the 2nd time, decocted 1.7 hours, merge decoction liquor twice, filter, filtrate decompression is concentrated in the time of 60 ℃ and measures relative density is 1.24 clear paste, again at vacuum 0.07Mpa, 75 ℃ of following vacuum dryings of temperature are ground into fine powder to doing, add appropriate amount of auxiliary materials, granulate drying, granulate, be pressed into 1000, every 0.5g.

Embodiment 2

In invention in force, also can adopt said Radix Scrophulariae 235g, Fructus Arctii 155g, Fructus Canarii 150g, Radix Platycodonis 155g, Radix Paeoniae Rubra 155g, Radix Puerariae 155g, Radix Rehmanniae 75g, Fructus Momordicae 235g and Radix Glycyrrhizae 115g make, wherein said components is mixed, decoct 2 times, add the water of 10 times of amounts of component gross weight 1430g the 1st time, decocted 2 hours, add the water of 8 times of amounts of component gross weight 1430g the 2nd time, decocted 1.5 hours, merge decoction liquor twice, filter, filtrate decompression is concentrated in the time of 60 ℃ and measures relative density is 1.23 clear paste, again at vacuum 0.06Mpa, 70 ℃ of following vacuum dryings of temperature are ground into fine powder to doing, add appropriate amount of auxiliary materials, granulate drying, granulate, be pressed into 1000, every 0.5g.

Embodiment 3

The present invention is when implementing, also can adopt following component to make: Radix Scrophulariae 245g, Fructus Arctii 165g, Fructus Canarii 165g, Radix Platycodonis 165g, Radix Paeoniae Rubra 165g, Radix Puerariae 165g, Radix Rehmanniae 85g, Fructus Momordicae 245g and Radix Glycyrrhizae 125g make, wherein said components is mixed, decoct 2 times, add the water of 9 times of amounts of component gross weight 1525g the 1st time, decocted 1.8 hours, add the water of 8 times of amounts of component gross weight 1525g the 2nd time, decocted 1.6 hours, merge decoction liquor twice, filter, filtrate decompression is concentrated in the time of 60 ℃ and measures relative density is 1.25 clear paste, again at vacuum 0.08Mpa, 80 ℃ of following vacuum dryings of temperature are ground into fine powder to doing, add appropriate amount of auxiliary materials, granulate drying, granulate, be pressed into 1000, every 0.5g.

In said components, by combination principle monarch, minister, help, make regulation, monarch is: Radix Scrophulariae, have YIN nourishing and the production of body fluid promoting, and eliminating fire and detoxication is used for thirsty dysphoria with smothery sensation, laryngopharynx swelling and pain etc.;

Minister is: Fructus Arctii has dispelling wind and heat pathogens, resolving toxin and disinhibiting the throat, laryngopharynx swelling and pain etc.; Fructus Canarii has relieving sore-throat by clearing away heat, promotes the production of body fluid, and detoxifcation is used for laryngopharynx swelling and pain, cough, excessive thirst etc.; Radix Platycodonis has lung qi dispersing, and sore-throat relieving eliminates the phlegm, and is used for pharyngalgia, hoarseness etc.;

Assistant is: Radix Paeoniae Rubra, have the removing heat from blood stasis of blood alive, and dispersing swelling and dissipating binds is used for carbuncle skin infection etc.; Radix Puerariae has the expelling pathogenic factors from muscles rash, and promoting the production of body fluid to quench thirst is used for the exterior syndrome cold and heat, and calentura is thirsty etc.; The Radix Rehmanniae (being Radix Rehmanniae) has clearing away heat and promoting production of body fluid, removing heat from blood, and yin nourishing is used for calentura and can falls excessive thirst, and interior-heat is quenched one's thirst etc.; Fructus Momordicae has clearing heat and moistening lung, and the laxation relieving constipation is used for lung-fire cough caused by dryness, pharyngalgia aphonia, dryness of the intestine constipation etc.;

Make to be Radix Glycyrrhizae, have invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription is used for weakness of the spleen and stomach, cough with copious phlegm, carbuncle sore tumefacting virus, cushion toxicity etc.

Above-mentioned each component organic assembling supports to have blood circulation promoting and blood stasis dispelling mutually, the detumescence cough-relieving, and relieving sore-throat by clearing away heat just in time is beneficial to control bottleneck throat disease, and through clinic trial, has obtained unexpected good result, and relevant experiment situation is as follows:

One, aspect treatment, be example with pharyngitis, laryngitis

A, pharyngitis patient 218 people, symptom is many with foreign body in pharynx sense, drying, it is main itching, mucosa has kermesinus, and the pharynx rear wall has the lymph follicle that is dispersed in, and secretions adhesion etc. is arranged, disease time is 3-30 days, and majority is chronic more than 30 days, and the longest medical history is more than 6 years, age is the patient that makes a definite diagnosis more than 16 years old, through using throat tablet for moisturizing and removing heat of the present invention, every day the 5-10 sheet, each 1-2 sheet, buccal, cured in acute patient 3-7 days, i.e. symptom complete obiteration recovers normal, 30 days-60 days transference cures of chronic patients, recovering normal person is 116 people, and wherein acute 58 people account for total 218 people's 53.2%, various symptoms have improver 99 people in various degree, account for 45.4%, no positive effect person 3 people account for 1.4%, total effective rate is 98.6%, has no adverse reaction.

B, laryngitic 196 people, the symptom hoarseness, itch, foreign body sensation, dry cough is main, with larynx, mucosa swelling, vocal congestion, closed bad etc. during sounding, the person of making a definite diagnosis is taken throat tablet for moisturizing and removing heat of the present invention, 5-10 days every day, each 1-2 sheet, buccal, acute patient 84 people cured in 3-7 days, the symptom complete obiteration, the person of getting well 76 people, the person of taking a favorable turn 8 people, total effective rate 100% (person of having no adverse reaction), chronic patients 112 people, 30-60 days complete eliminator 58 people of symptom, symptom improvement person 53 people, 1 people does not have positive effect, total effective rate reaches 99.5%, has no adverse reaction.

C, to the bottleneck throat discomfort, treat as partial symptoms patient 158 people such as pharynx, throat's redness, itching throat, pharyngalgia, cough, hoarseness, every day, the 5-10 sheet was sucked clothes throat tablet for moisturizing and removing heat of the present invention, each 1-2 sheet, all there was symptom in various degree to take a turn for the better in 3-10 days, all can consolidate more than 30 days, have no adverse reaction.

Two, about the prevention situation

To healthy population, take through 518 people, every day 3 times, morning, noon and afternoon each 1 time, each 2, buccal, the bottleneck throat disease incidence is one of not enough percentage (＜1%) in 3 years, only has 4 people to take place, and warp is at same environment, crowd under the similarity condition adds up sickness rate more than 40%, and obvious prevention effect of the present invention is very outstanding.

Above-mentioned situation shows that it is dual-purpose that the present invention has control, ill curing the disease, and anosis diseases prevention is the innovation greatly of one on health care, the pharmaceutical products, economic and social benefit is huge.

Claims (4)

1. throat tablet for moisturizing and removing heat, it is characterized in that, by the weight meter: Radix Scrophulariae 230-250g, Fructus Arctii 150-170g, Fructus Canarii 150-170g, Radix Platycodonis 150-170g, Radix Paeoniae Rubra 150-170g, Radix Puerariae 150-170g, Radix Rehmanniae 70-90g, Fructus Momordicae 220-260g and Radix Glycyrrhizae 110-130g make, wherein, above-mentioned each component is mixed, add each component gross weight 8-10 water doubly at every turn, decoct 2 times, each 1.5-2 time hour, merge decoction liquor twice, filter, measuring relative density when filtrate decompression is concentrated into 60 ℃ is the clear paste of 1.23-1.25, again at vacuum 0.06-0.08Mpa, temperature 70-80 ℃ of following vacuum drying is ground into fine powder to doing, and adds appropriate amount of auxiliary materials, granulate, drying, granulate, compacting is in flakes.

2. throat tablet for moisturizing and removing heat according to claim 1, it is characterized in that, by the weight meter: Radix Scrophulariae 240g, Fructus Arctii 160g, Fructus Canarii 160g, Radix Platycodonis 160g, Radix Paeoniae Rubra 160g, Radix Puerariae 160g, Radix Rehmanniae 80g, Fructus Momordicae 240g and Radix Glycyrrhizae 120g make, wherein said components is mixed, decoct 2 times, add the water of 10 times of amounts of component gross weight 1480g the 1st time, decocted 2 hours, add the water of 8 times of amounts of component gross weight 1480g the 2nd time, decocted 1.7 hours, merge decoction liquor twice, filter, filtrate decompression is concentrated into and measures relative density in the time of 60 ℃ is 1.24 clear paste, again at vacuum 0.07Mpa, 75 ℃ of following vacuum dryings of temperature are to doing, be ground into fine powder, add appropriate amount of auxiliary materials, granulate, dry, granulate is pressed into 1000, every 0.5g.

3. throat tablet for moisturizing and removing heat according to claim 1, it is characterized in that, by the weight meter: Radix Scrophulariae 235g, Fructus Arctii 155g, Fructus Canarii 150g, Radix Platycodonis 155g, Radix Paeoniae Rubra 155g, Radix Puerariae 155g, Radix Rehmanniae 75g, Fructus Momordicae 235g and Radix Glycyrrhizae 115g make, wherein said components is mixed, decoct 2 times, the decocting that adds 10 times of amounts of component gross weight 1430g for the 1st time boiled 2 hours, add the water of 8 times of amounts of component gross weight 1430g the 2nd time, decocted 1.5 hours, merge decoction liquor twice, filter, filtrate decompression is concentrated in the time of 60 ℃ and measures relative density is 1.23 clear paste, again at vacuum 0.06Mpa, 70 ℃ of following vacuum dryings of temperature are ground into fine powder to doing, add appropriate amount of auxiliary materials, granulate drying, granulate, be pressed into 1000, every 0.5g.

4. throat tablet for moisturizing and removing heat according to claim 1, it is characterized in that, by the weight meter: Radix Scrophulariae 245g, Fructus Arctii 165g, Fructus Canarii 165g, Radix Platycodonis 165g, Radix Paeoniae Rubra 165g, Radix Puerariae 165g, Radix Rehmanniae 85g, Fructus Momordicae 245g and Radix Glycyrrhizae 125g make, wherein said components is mixed, decoct 2 times, add the water of 9 times of amounts of component gross weight 1525g the 1st time, decocted 1.8 hours, add the water of 8 times of amounts of component gross weight 1525g the 2nd time, decocted 1.6 hours, merge decoction liquor twice, filter, filtrate decompression is concentrated into and measures relative density in the time of 60 ℃ is 1.25 clear paste, at vacuum 0.08Mpa, 80 ℃ of following vacuum dryings of temperature are to doing, be ground into fine powder, add appropriate amount of auxiliary materials, granulate, dry, granulate is pressed into 1000, every 0.5g.