CN102224248B - Lcmv-gp-假型化vsv载体和肿瘤浸润性的病毒生产细胞用于肿瘤的治疗 - Google Patents
Lcmv-gp-假型化vsv载体和肿瘤浸润性的病毒生产细胞用于肿瘤的治疗 Download PDFInfo
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Abstract
Description
Claims (17)
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DE102008050860A DE102008050860A1 (de) | 2008-10-08 | 2008-10-08 | LCMV-GP-VSV-Pseudotypvektoren und tumorinfiltrierende Virenproduzentenzellen zur Therapie von Tumoren |
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US10265357B2 (en) | 2008-10-08 | 2019-04-23 | Viratherapeutics Gmbh | Compositions, methods and uses for treating solid tumors using LCMV-GP-VSV pseudotype vectors |
DE102008050860A1 (de) | 2008-10-08 | 2010-04-15 | Dorothee Von Laer | LCMV-GP-VSV-Pseudotypvektoren und tumorinfiltrierende Virenproduzentenzellen zur Therapie von Tumoren |
CN102858959B (zh) | 2009-12-10 | 2016-02-24 | 渥太华医院研究院 | 溶瘤弹状病毒 |
WO2012167382A1 (en) | 2011-06-08 | 2012-12-13 | Children's Hospital Of Eastern Ontario Research Institute Inc. | Compositions and methods for glioblastoma treatment |
BR112015013669A2 (pt) * | 2012-12-12 | 2017-11-14 | Childrens Hospital Of Eastern Ontario Res Institute Inc | composições e métodos para o tratamento de cânceres cerebrais |
RU2684211C2 (ru) | 2013-02-21 | 2019-04-04 | Тёрнстоун Лимитед Партнершип | Композиция вакцины |
WO2015077714A1 (en) | 2013-11-22 | 2015-05-28 | Yale University | Chimeric vsv virus compositions and methods of use thereof for treatment of cancer |
CA3024653A1 (en) * | 2016-05-19 | 2017-11-23 | Turnstone Limited Partnership | Pseudotyped oncolytic rhabdoviruses and their use in combination therapy |
EP3246410A1 (en) * | 2016-05-19 | 2017-11-22 | Klinikum rechts der Isar der Technischen Universität München | Vsv/ndv hybrid viruses for oncolytic therapy of cancer |
CN113348244A (zh) | 2018-11-23 | 2021-09-03 | 维拉治疗有限公司 | Vsv嵌合载体 |
EP3669893A1 (en) * | 2018-12-20 | 2020-06-24 | Universidad Autónoma de Madrid | Treatment of p53 mutated/modified cancer-forms with parvovirus |
TW202043466A (zh) | 2019-01-25 | 2020-12-01 | 德商百靈佳殷格翰國際股份有限公司 | 編碼ccl21之重組棒狀病毒 |
EP3987041A1 (en) | 2019-06-21 | 2022-04-27 | Boehringer Ingelheim International Gmbh | Novel mechanism to control rna virus replication and gene expression |
WO2021211704A1 (en) * | 2020-04-14 | 2021-10-21 | Washington University | Sars cov-2 vaccines and high throughput screening assays based on vesicular stomatitis virus vectors |
CR20220586A (es) | 2020-05-19 | 2023-01-09 | Boehringer Ingelheim Int | Moléculas de fijación para el tratamiento de cáncer |
PE20231293A1 (es) | 2020-06-03 | 2023-08-22 | Boehringer Ingelheim Int | Rhabdovirus recombinante que codifica una proteina de fusion fc de dominio extracelular cd80 |
CN116171322A (zh) * | 2020-07-10 | 2023-05-26 | 勃林格殷格翰国际有限公司 | 从细胞培养物中制备纯化的弹状病毒的方法 |
AU2021341521A1 (en) | 2020-09-14 | 2023-03-30 | Boehringer Ingelheim International Gmbh | Heterologous prime boost vaccine |
US20230183650A1 (en) | 2021-07-09 | 2023-06-15 | Boehringer Ingelheim International Gmbh | VSV Rescue |
US20240033336A1 (en) | 2022-03-16 | 2024-02-01 | Boehringer Ingelheim International Gmbh | Tumor antigens, compounds comprising the tumor antigens and uses thereof |
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US7153510B1 (en) * | 1995-05-04 | 2006-12-26 | Yale University | Recombinant vesiculoviruses and their uses |
DE19856463B4 (de) | 1998-11-26 | 2006-02-02 | Heinrich-Pette-Institut | Retrovirale, mit LCMV pseudotypisierte Hybrid-Vektoren |
NZ517573A (en) * | 1999-09-17 | 2004-02-27 | Pro Virus Inc | Sequences of the oncolytic virus strain vesicular stromatitis virus (VSV) |
JP2004537305A (ja) * | 2001-07-11 | 2004-12-16 | ユニバーシティー オブ マイアミ | 腫瘍細胞の処置のための組換えvsv |
US7135339B2 (en) * | 2003-11-20 | 2006-11-14 | University Of Iowa Research Foundation | Methods for producing and using in vivo pseudotyped retroviruses using envelope glycoproteins from lymphocytic choriomeningitis virus (LCMV) |
DE102004034461B4 (de) | 2004-07-16 | 2008-02-07 | Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus | Gentherapie solider Tumore durch retrovirale, mit Arenavirus-Glykoprotein pseudotypisierte Vektoren |
US10265357B2 (en) | 2008-10-08 | 2019-04-23 | Viratherapeutics Gmbh | Compositions, methods and uses for treating solid tumors using LCMV-GP-VSV pseudotype vectors |
DE102008050860A1 (de) | 2008-10-08 | 2010-04-15 | Dorothee Von Laer | LCMV-GP-VSV-Pseudotypvektoren und tumorinfiltrierende Virenproduzentenzellen zur Therapie von Tumoren |
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US9650649B2 (en) | 2017-05-16 |
US20110250188A1 (en) | 2011-10-13 |
CN102224248A (zh) | 2011-10-19 |
EP2597154A1 (de) | 2013-05-29 |
PT2597154E (pt) | 2014-10-30 |
EP2350295B1 (de) | 2013-05-15 |
EP2597154B1 (de) | 2014-09-03 |
PT2350295E (pt) | 2013-08-05 |
ES2523294T3 (es) | 2014-11-24 |
US9963718B2 (en) | 2018-05-08 |
CA2739963A1 (en) | 2010-04-15 |
ES2424026T3 (es) | 2013-09-26 |
JP4910077B2 (ja) | 2012-04-04 |
WO2010040526A8 (de) | 2011-05-19 |
WO2010040526A1 (de) | 2010-04-15 |
CA2739963C (en) | 2012-04-03 |
DE102008050860A1 (de) | 2010-04-15 |
US20170211096A1 (en) | 2017-07-27 |
JP2012504944A (ja) | 2012-03-01 |
EP2350295A1 (de) | 2011-08-03 |
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