CN102188550A - Topical preparation for treating tendon and bone injuries - Google Patents
Topical preparation for treating tendon and bone injuries Download PDFInfo
- Publication number
- CN102188550A CN102188550A CN2011101182022A CN201110118202A CN102188550A CN 102188550 A CN102188550 A CN 102188550A CN 2011101182022 A CN2011101182022 A CN 2011101182022A CN 201110118202 A CN201110118202 A CN 201110118202A CN 102188550 A CN102188550 A CN 102188550A
- Authority
- CN
- China
- Prior art keywords
- external preparation
- radix
- wounded
- sick
- muscles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
The invention discloses an external preparation for treating tendon and bone injuries, which comprises the following active ingredients extracted from traditional Chinese medicinal herbs in parts by weight: 100 to 200 parts of menthol and 50 to 100 parts of camphor. The external preparation in the invention has high dosage, is in conformity with the characteristic of high dosage of traditional Chinese medicine, has the efficacy of promoting blood circulation for removing blood stasis, relieving rigidity of muscles and activating collaterals, reducing swelling for relieving pain, and expelling wind and removing dampness, can be used for treating tendon and bone injuries such as traumatic injury, fracture, dislocation, rheumatic lumbago, muscle injury strain, myalgia, and the like, and has the advantages of rapid effect, short period of treatment and fine curative effect.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of sick and wounded external preparation of muscles and bones for the treatment of.
Background technology
Muscles and bones is sick and wounded to be one of common disease of modern, and treatment means mainly is divided into western medical treatment and Chinese traditional treatment.The treatment means of doctor trained in Western medicine many with anti-inflammation, reset, methods such as planter cast, operation, but do not have effective medicine.And the traditional Chinese medical science belongs to the traditional diagnosis and treatment means of China, and the medicine that treatment muscles and bones is sick and wounded is numerous, has their own characteristics each.
Summary of the invention
The object of the present invention is to provide and a kind ofly can effectively treat the sick and wounded external preparation of each analgesic bone.
For achieving the above object, the present invention by the following technical solutions:
Treatment muscles and bones sick and wounded external preparation, contain active component that following parts by weight of Chinese traditional medicine material extracts and Mentholum 100-200 weight portion, Camphora 50-100 weight portion:
As preferably, the sick and wounded external preparation of treatment muscles and bones of the present invention contains active component that following parts by weight of Chinese traditional medicine material extracts and Mentholum 150 weight portions, Camphora 75 weight portions:
Further, described each Chinese crude drug extraction method of active ingredients is as follows:
Radix Notoginseng, Radix Saposhnikoviae, Radix Angelicae Sinensis, the Radix Angelicae Dahuricae, Rhizoma Polygoni Cuspidati, Rhizoma Et Radix Notopterygii and Radix Angelicae Pubescentis extract with alcoholic solution, alcohol extract and medicinal residues A, alcohol extract concentrate extractum A;
Medicinal residues A is with all the other Chinese crude drug water extraction, aqueous extract, aqueous extract concentrate extractum B;
Merge extractum A and extractum B.
As preferably, described external preparation is an emplastrum.
External preparation dosage of the present invention is big, meet the big characteristics of Chinese medicine dosage, effect with blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, reducing swelling and alleviating pain, expelling wind and removing dampness, can be used for the sick and wounded treatments of muscles and bones such as traumatic injury, fracture-dislocation, lumbago due to pathogenic wind-dampness, the strain of flesh wound, myalgia, instant effect, short treating period, good effect.
The specific embodiment
The sick and wounded external preparation of treatment muscles and bones of the present invention, form by active component and Mentholum 100-200 weight portion, Camphora 50-100 weight portion that following parts by weight of Chinese traditional medicine material extracts:
Effect of respectively distinguishing the flavor of Chinese crude drug of the present invention cures mainly as follows:
Radix Notoginseng: dissipating blood stasis hemostasis, subduing swelling and relieving pain.Cure mainly spitting of blood, spit blood, epistaxis is had blood in stool, metrorrhagia, and traumatic hemorrhage, breast ventral spine pain, tumbling down swells and ache.
Radix Dipsaci: invigorating the liver and kidney, strengthening bone and muscle, blood circulation regulating.Cure mainly deficiency of the liver and kindey, soreness of the waist and knees; Fracture; Woman uterine bleeding, frequent fetal movement.
Rhizoma Polygoni Cuspidati: promoting blood circulation to remove obstruction in the collateral, clearing away heat-damp and promoting diuresis.Cure mainly diseases such as women's stasis of blood stagnate-closed warp, traumatic injury, rheumatic arthralgia, jaundice due to damp-heat, stranguria caused by urinary stone.
Herba Lycopodii: expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons to promote blood circulation.Cure mainly anemofrigid-damp arthralgia, joint aches, skin numbness, tetraparesis, edema, traumatic injury.
Herba speranskiae tuberculatae: dispel the wind, dehumidifying, Shujin is invigorated blood circulation, pain relieving.Cure mainly rheumatic arthralgia, muscles and bones contracture, the disturbance of lower legs due to pathogenic cold and dampness, skin ulcer tinea toxic swelling.
Radix Angelicae Pubescentis: dispel the wind, win and wet, cold expelling, pain relieving.Cure mainly anemofrigid-damp arthralgia, soreness of waist and knee joint, trick spasm and pain, chronic tracheitis, headache, toothache.
Cortex Phellodendri: heat and toxic materials clearing away medicine; Heat clearing and dampness removing medicine.Cure mainly: hygropyretic dysentery, have loose bowels, jaundice; Nocturnal emission stranguria with turbid discharge, leukorrhagia; The hectic fever due to YIN-deficiency consumptive fever; And aphtha of the mouth and tongue; Conjunctival congestion and swelling pain; Skin sore; Skin eczema.
Radix Cynanchi Paniculati: the removing dampness of dispeling the wind, antalgesic-antipruritic.Cure mainly rheumatic arthralgia, stomachache distension, toothache, lumbago, injury from falling down, urticaria, eczema.
Rhizoma Et Radix Notopterygii: cold expelling, dispel the wind dehumidifying, pain relieving.Cure mainly the anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back.
Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Cure mainly blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.The Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.
Rhizoma Drynariae: the kidney invigorating bone strengthening continues and hinders pain relieving.Cure mainly lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, and the muscles and bones folding is hindered; The external treatment alopecia areata, vitiligo.
Cortex erythrinae: wind-damp dispelling, the meridian dredging, parasite killing.Cure mainly rheumatic arthralgia, dysentery, toothache, scabies.
Downy rosemyrtle root: nourish blood collateral dredging.Be used for rheumatism numbness, lumbar muscle strain.
Radix Glycyrrhizae: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Cure mainly weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction.
Semen Persicae: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.Cure mainly amenorrhea, dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.
Radix Clematidis: expelling wind and removing dampness, removing obstruction in the collateral to relieve pain.Cure mainly rheumatic arthralgia, muscles and bones disease such as ache.
Herba Lycopi: promoting blood flow to regulate menstruation, blood stasis dispelling eliminating carbuncle, inducing diuresis to remove edema.Be used for traumatic injury, pain caused by ecchymoma, sore and toxic.
Flos Lonicerae: heat-clearing and toxic substances removing, dispelling wind and heat pathogens.Be used for the carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease.
The Radix Angelicae Dahuricae: dispel the wind dampness, detumescence, pain relieving.Cure mainly headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp stomachache, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.
Radix Saposhnikoviae: deliver diffusing wind, removing dampness to relieve pain, relieving convulsion, antidiarrheal.Cure mainly headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus disease.
Fructus Chaenomelis: help digestion, anthelmintic, heat clearing away is dispeled the wind.Cure mainly stomachache, dyspepsia, lung-heat dry cough, galactostasis, eczema, parasitic disease, diseases such as trick spasm pain.
Herba Lycopodii: wind-expelling pain-stopping medicine, relaxing muscles and tendons and activating QI and blood in the collateral.Cure mainly rheumatic arthralgia, lumbar muscle strain, traumatic injury.
Camphora: sensible, parasite killing, pain relieving is warded off dirty.Cure mainly trusted subordinate's distending pain, beriberi, skin infection scabies, toothache, traumatic injury.
Mentholum: dispelling wind medicine, antipyretic.Cure mainly anemopyretic cold, headache, conjunctival congestion, laryngopharynx swelling and pain, toothache, skin pruritus.
Radix Notoginseng, Radix Angelicae Sinensis, Semen Persicae, Herba Lycopi, Rhizoma Polygoni Cuspidati in the present invention prescription have the merit of blood circulation and promoting silt, reducing swelling and alleviating pain, the monarch drug of the side's of being medicine, and wherein Radix Notoginseng is this side's a key medicine; Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, the Radix Angelicae Dahuricae, Radix Saposhnikoviae, Radix Cynanchi Paniculati, Cortex erythrinae, Herba Lycopodii, Radix Dipsaci, Fructus Chaenomelis, Rhizoma Drynariae, the effect of tool expelling wind and removing dampness is ministerial drug; Assistant is with Cortex Phellodendri, Flos Lonicerae, Herba Lycopodii, Herba speranskiae tuberculatae heat-clearing and toxic substances removing, relaxing muscles and tendons and activating QI and blood in the collateral; Add messenger drug Radix Clematidis, downy rosemyrtle root, Radix Glycyrrhizae, the side's of helping medicine expelling wind and removing dampness, blood nourishing acupuncture-stimulating, relieving spasm to stop pain, the effect of coordinating the actions of various ingredients in a prescription.Mutual reinforcement between, the mutual-assistance of side's medicine are made up, and bring into play the merit of blood circulation and promoting silt, reducing swelling and alleviating pain, expelling wind and removing dampness, also play the effect of heat-clearing and toxic substances removing, relaxing muscles and tendons and activating QI and blood in the collateral and relieving spasm to stop pain, blood nourishing acupuncture-stimulating, bring out the best in each other.
Application Example
Utilize the present invention can be prepared into various external preparation, existing is example explanation its preparation method and curative effect with the emplastrum.
One, prescription:
Two, the method for making of emplastrum:
1, get the Mentholum of recipe quantity and Camphora and grind to make altogether and melt, airtight standby;
2, Radix Notoginseng, Radix Saposhnikoviae, Radix Angelicae Sinensis, the Radix Angelicae Dahuricae, Rhizoma Polygoni Cuspidati, Rhizoma Et Radix Notopterygii and the Radix Angelicae Pubescentis of getting recipe quantity is ground into particulate, puts in the percolation bucket, adds 10 times of amount 95% ethanol, soaks 12 hours, extracts with percolation, must alcohol extract and medicinal residues A; Ethanol in the reclaim under reduced pressure alcohol extract is concentrated into relative density and is 1.2～1.24 (25 ℃) extractum, and is standby;
3, medicinal residues A is added 10 times of water gagings with all the other Chinese crude drugs of respectively distinguishing the flavor of of recipe quantity, soak half an hour, decocts three times, each 1.0 hours, decocting liquid merged, filtration, and filtrate is concentrated into the extractum B that relative density is 1.20～1.24 (25 ℃);
4, extractum A and extractum B are merged, adding Mentholum, Camphora melt liquid altogether, stir to make to be uniformly dispersed, and get Chinese medicine extraction extractum;
5, get Resina persicae in addition, tragcanth adds the suitable quantity of water swelling, heating makes dissolving, adds polyvinyl alcohol, glycerol, Kaolin mix homogeneously and makes substrate; With substrate and Chinese medicine extraction extractum mixing and stirring, be applied on the non-woven fabrics, the lid lining is cut into 11cm * 14cm/ and pastes, and packing is promptly.Wherein, the proportioning of adhesive and wetting agent is: Resina persicae: tragcanth: water=1.5: 1.5: 6; The proportioning of excipient, wetting agent and filler is: polyvinyl alcohol: glycerol: Kaolin=3: 3: 5.
Three, toxicological experiment:
1, skin acute toxicity test.
Get 20 rabbit, about the about 2kg of body weight, male and female half and half are divided into blank group (substrate 8.0g/ only), 4 groups of emplastrumes of the present invention: intact skin and damaged skin, each 2 dosage: medication (8.0g/ only, 2g/ only), 4 every group.With tame rabbit back spinal column both sides unhairing, the depilation area is about 13cmx16cm.24h checks whether skin of unhairing is injured after the unhairing.Injured rabbit is unfit to do the toxicity test of intact skin.The making of damaged skin: adopt the disposable syringe syringe needle on depilation district sterilization skin, to mark " # " shape otch.Each about 5cm of length and width, the degree of depth is 2-3mm, not damage subcutaneous tissue and oozing of blood degree of being is arranged.Patch is affixed on the depilation district, and every animal sub-cage rearing is behind the maintenance 24h, with the residual medicine of warm water flush away, observe animal 1,24,48, symptoms such as 7 days body weight of 72h to the, diet, defecation, activity, skin, hair, eye, mucosa and breathing, and with matched group relatively.
Result of the test shows, behind the removal medicine 1,24,48,72h to the 7 days observes the rabbit of intact skin group and damaged skin group. find that its behavior, activity, fur gloss, eye and conjunctiva, breathing, diet all act normally, smear the position and do not have situations such as erythema and edema that not seeing has any poisoning symptom, do not see death yet, compare indifference with the substrate matched group.To compare with the substrate matched group. the rabbit net gain difference of skin complete group and skin injury group is remarkable (P＞0.05) not.Result of the test shows that emplastrum of the present invention does not have acute toxic reaction through the skin administration, and degree of safety is bigger.
2, local skin irritation test
12 of adult healthy rabbit are adopted the contrast of consubstantiality left and right sides self.Divide intact skin group and damaged skin group, 6 every group, male and female half and half.Unhairing and damaged skin are made the same.Unhairing district, the left side invention emplastrum (content of dispersion is 16g) that loses money in a business, substrate (dosage is 16g) is in contrast pasted in unhairing district in right side.Patch is affixed on depilation district, sub-cage rearing.Administration every day 1 time, 7d continuously.Behind the last administration 24h, with warm water flush away residual medicine, observe animal and remove and be subjected to behind the reagent thing 1,24,48,72h pastes the medicine position and has or not erythema and edema situation, and whether situations such as pigmentation, petechia, pachylosis or epidermatic atrophy are arranged.
Result of the test shows, emplastrum of the present invention and substrate are at rabbit intact skin and damaged skin successive administration after 1 week, remove the individual animal idol inadequate visible erythema is arranged, and outside can very fast disappearance, all the other animals do not have any untoward reaction, no erythema and edema situation, situations such as non-pigment calmness, petechia, pachylosis or epidermatic atrophy occur.
3, skin anaphylactic test
30 of albino guinea-pigs are divided into 3 groups at random, i.e. matrix group, emplastrum group of the present invention and positive controls, 10 every group, male and female half and half.24h before administration, with guinea pig back spinal column both sides unhairing, the depilation area is 3cm * 3cm.1. sensitization contact: get emplastrum of the present invention (content of dispersion 0.2g) in left side depilation district.Matrix group substrate (weight 0.2g), positive controls 0.2mL 1%2-4-dinitro-chloro-benzene (lot number 881201), sub-cage rearing continues 6h, and the 7th day and the 14th day repeats totally 3 times in the same way 1 time.(excite contact: 14d after last is subjected to the reagent thing to sensitization, (content of dispersion 0.2g) is affixed on depilation district, right side, back with emplastrum of the present invention, matrix group 0.2g substrate, positive controls 0.2mL0.1%2, the 4-dinitro-chloro-benzene removes behind the 6h and is subjected to the reagent thing, at once observe, in 24,48,72h observes the skin allergic reaction situation once more then.Notice simultaneously whether observe animal has serious whole body allergy such as asthma, astasia or shock.
Emplastrum of the present invention is to sensitization of skin reaction test result: matrix group is skin allergic reaction situations such as show speckle, edema not; Emplastrum group of the present invention only has individual animal promptly to be carved with slight erythematous response.The sensitization rate is 10%, reacts to 24h and disappears; Skin allergic reaction situations such as tangible erythema, edema appear in positive controls.Integrated value is very high.The sensitization rate reaches 100%.Serious whole body allergy such as asthma, astasia or shock all do not appear in 3 groups of Cavia porcelluss.The result shows: emplastrum of the present invention and substrate are to the essentially no sensitivity response of skin, and emplastrum of the present invention has erythematous response in the individual animal idol but can die away.
Four, clinical application research
By the observation on Clinical Application to 60 routine patients, emplastrum of the present invention has the effect of blood circulation and promoting silt, relaxing muscles and tendons and activating QI and blood in the collateral, reducing swelling and alleviating pain, expelling wind and removing dampness.Traumatic injury, fracture-dislocation, lumbago due to pathogenic wind-dampness, flesh are hindered sick and wounded rapid-action of muscles and bones such as strain, muscle disease, good effect.
1, detumescence: soft tissue injury broke hemorrhage after human body limb was hit by external force, fracture end is hemorrhage, the injury region vascular permeability strengthens, ooze out increase, reason all causes injured limb to synovium of joint or the alluvial of intraarticular liquid forms swelling because of hyperemia is oozed out etc., then acts on tissue for exopathogen by theory of Chinese medical science, damages muscles and bones, meridians are obstructed, and coagulation of QI-blood forms swelling.Its principal agent hemostasis of emplastrum of the present invention, blood stasis dispelling, detumescence, pain relieving, circulation of qi promoting, invigorate blood circulation, reduce ooze out hemorrhage, thereby play the detumescence effect.According to traditional Chinese medical science viewpoint, both degasification is to stagnate because of separating, dredging the meridian and reaching except that silt repercussive purpose.
2, pain relieving: local swelling makes and organizes bone voltage rise height after hindering, and physics and chemical factor that the metabolite that tissue injury and anoxia discharged (k+, h+, histamine, multicolored amine) forms excite nerve tip and produce pain.Emplastrum of the present invention can alleviate organizes internal pressure, improves anoxic conditions, and have blood circulation promoting and blood stasis dispelling, remove swelling and analgesic effect, be " stagnation of QI and blood may bring about pain, general rule are not bitterly " by theory of Chinese medical science.
3, microcirculation improvement: the effective ingredient in emplastrum prescription drug of the present invention such as the Radix Notoginseng, ginsenoside Rb1, Rg1, Re can effectively protect blood vessel endothelium, promote the effect of vascular health.The pharmacological action of Semen Persicae has the reduction vascular resistance, improves hemodynamic situation.Water decoction and extract have analgesia, antiinflammatory, antibiotic, anti-allergic effects.Herba Lycopi's pharmacological action: can the antagonist outer thrombosis of water decoction, have slight anticoagulant system with the effect that strengthens fibrinolytic.Compatibilities such as Radix Notoginseng, Semen Persicae, Herba Lycopi use, and improve the hemodynamics recurrent state, quicken the absorption of wound general character medium, thereby reach the purpose of microcirculation improvement.Clinical practice result to 60 routine patients shows that emplastrum of the present invention has tangible detumescence, pain relieving and promotes the union of fracture effect surgery and patient with bone fracture.
The typical clinical case:
1, beam, the man, 41 years old, a high position was landed and is caused left lower limb tibia crackle to occur, can not land, and through emplastrum external application of the present invention 4 times, activity does not have any sequela freely so far.
2, Luo, the man, 14 years old, break, caused the left foot ankle to sprain redness when movable accidentally, and after emplastrum external application 2 of the present invention was pasted, red and swollen and pain all disappeared substantially, and it is normal that movable function recovers.
3, grandson, the woman, 36 years old, divine force that created the universe body injured by a crashing object to clavicle stage casing, right side fracture, through emplastrum external application of the present invention after 3 days, pain relief, external application is after 4 days again, and pain and sensation of aching disappear substantially, union of fracture.
Claims (4)
1. treatment muscles and bones sick and wounded external preparation is characterized in that, contains active component that following parts by weight of Chinese traditional medicine material extracts and Mentholum 100-200 weight portion, Camphora 50-100 weight portion:
2. the sick and wounded external preparation of treatment muscles and bones according to claim 1 is characterized in that, contains active component that following parts by weight of Chinese traditional medicine material extracts and Mentholum 150 weight portions, Camphora 75 weight portions:
3. the sick and wounded external preparation of treatment muscles and bones according to claim 1 is characterized in that described each Chinese crude drug extraction method of active ingredients is as follows:
Radix Notoginseng, Radix Saposhnikoviae, Radix Angelicae Sinensis, the Radix Angelicae Dahuricae, Rhizoma Polygoni Cuspidati, Rhizoma Et Radix Notopterygii and Radix Angelicae Pubescentis extract with alcoholic solution, alcohol extract and medicinal residues A, alcohol extract concentrate extractum A;
Medicinal residues A is with all the other Chinese crude drug water extraction, aqueous extract, aqueous extract concentrate extractum B;
Merge extractum A and extractum B.
4. the sick and wounded external preparation of treatment muscles and bones according to claim 1 is characterized in that described external preparation is an emplastrum.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110118202 CN102188550B (en) | 2011-05-09 | 2011-05-09 | Topical preparation for treating tendon and bone injuries |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110118202 CN102188550B (en) | 2011-05-09 | 2011-05-09 | Topical preparation for treating tendon and bone injuries |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102188550A true CN102188550A (en) | 2011-09-21 |
| CN102188550B CN102188550B (en) | 2013-08-28 |
Family
ID=44597985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201110118202 Expired - Fee Related CN102188550B (en) | 2011-05-09 | 2011-05-09 | Topical preparation for treating tendon and bone injuries |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102188550B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579583A (en) * | 2012-03-07 | 2012-07-18 | 河南省医药科学研究院 | External patch for treating injury of tendons and muscles |
| CN105288712A (en) * | 2015-10-12 | 2016-02-03 | 希雅图（上海）新材料科技股份有限公司 | Production technology of multi-purpose saturated impregnation non-woven novel material |
| CN116850228A (en) * | 2023-08-21 | 2023-10-10 | 广州白云山医药集团股份有限公司白云山何济公制药厂 | Pseudo-ginseng ointment for treating traumatic injuries and rheumatism and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101623415A (en) * | 2009-08-07 | 2010-01-13 | 葛超顺 | Traditional Chinese medicine preparation for treating fractures and bone injuries |
| CN101642496A (en) * | 2008-08-07 | 2010-02-10 | 刘庆荣 | Chinese medicinal preparation for treating bone injury diseases |
-
2011
- 2011-05-09 CN CN 201110118202 patent/CN102188550B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101642496A (en) * | 2008-08-07 | 2010-02-10 | 刘庆荣 | Chinese medicinal preparation for treating bone injury diseases |
| CN101623415A (en) * | 2009-08-07 | 2010-01-13 | 葛超顺 | Traditional Chinese medicine preparation for treating fractures and bone injuries |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102579583A (en) * | 2012-03-07 | 2012-07-18 | 河南省医药科学研究院 | External patch for treating injury of tendons and muscles |
| CN105288712A (en) * | 2015-10-12 | 2016-02-03 | 希雅图（上海）新材料科技股份有限公司 | Production technology of multi-purpose saturated impregnation non-woven novel material |
| CN105288712B (en) * | 2015-10-12 | 2018-09-04 | 澜宁管道(上海)有限公司 | A kind of production technology of multi-functional saturation impregnated nonwoven new material |
| CN116850228A (en) * | 2023-08-21 | 2023-10-10 | 广州白云山医药集团股份有限公司白云山何济公制药厂 | Pseudo-ginseng ointment for treating traumatic injuries and rheumatism and preparation method thereof |
| CN116850228B (en) * | 2023-08-21 | 2024-02-06 | 广州白云山医药集团股份有限公司白云山何济公制药厂 | Pseudo-ginseng ointment for treating traumatic injuries and rheumatism and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102188550B (en) | 2013-08-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100551422C (en) | A kind of endo-medicine for the treatment of intervertebral disk hernia | |
| CN103550517B (en) | A kind of medicine of Hepatoma therapy | |
| CN103751310B (en) | A kind of traditional Chinese medicine for external application and its preparation method treating fascitis | |
| CN102793883B (en) | Plaster for treating intervertebral disc protrusion and cervical spondylosis | |
| CN103751633A (en) | Traditional Chinese medicinal composition for treating varicose vein of lower limb and preparation method thereof | |
| CN103705751B (en) | Chinese medicine composition being used for the treatment of lumbago due to pathogenic wind-dampness and preparation method thereof | |
| CN103463297B (en) | A kind of Chinese medicine composition for the treatment of eczema scrotum and its production and use | |
| CN102836409B (en) | Traditional Chinese medicine for treating postpartum lochiorrhea and preparation method | |
| CN102772712B (en) | Traditional Chinese medicine composition for treating heat-toxicity, flourishing and blood stasis type diabetic foot | |
| CN100431577C (en) | Medicine for treating femoral head necrosis and femur neck fracture and preparation method thereof | |
| CN103638237B (en) | External traumatic medicine composition, external traumatic medicinal oil and preparation method thereof | |
| CN102188550B (en) | Topical preparation for treating tendon and bone injuries | |
| CN104161823B (en) | A kind of Chinese medicine for the treatment of aseptic necrosis of femoral head | |
| CN110585400A (en) | Herbal health-care ointment | |
| CN104548054A (en) | Traditional Chinese medicine composition for treating gynecological diseases and preparation methods of traditional Chinese medicine composition | |
| CN104127831A (en) | Traditional Chinese medicine for treating pantalgia after childbirth caused by exogenous pathogen and preparation method thereof | |
| CN102872420B (en) | Medicine for treating rheumatic arthritis and preparation method thereof | |
| CN101953930A (en) | Externally-applied traditional Chinese medicine for treating tinea capitis | |
| CN104258285A (en) | Medicine for treating lumbar bone hyperplasia through internal and external application and preparation method thereof | |
| CN104398664A (en) | Zhuang pharmaceutical composition for treating anovulatory infertility | |
| CN104623376A (en) | Medicament for treating prosopalgia | |
| CN103751467A (en) | Traditional Chinese medicine composition for treating lumbar and back myofascitis and preparation method thereof | |
| CN102805845B (en) | Drug for curing chronic ulcer of leg and preparation method thereof | |
| CN104758830A (en) | Traditional Chinese medicine composition for treating bone disease and skin injury and preparation method of traditional Chinese medicine composition | |
| CN104257965A (en) | Traditional Chinese medicine for treating knee joint hyperostosis via oral and external administration and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130828 Termination date: 20150509 |
|
| EXPY | Termination of patent right or utility model |