CN102178629A - Silybum marianum essential oil skin-care cream and preparation method thereof - Google Patents
Silybum marianum essential oil skin-care cream and preparation method thereof Download PDFInfo
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- CN102178629A CN102178629A CN2011100979333A CN201110097933A CN102178629A CN 102178629 A CN102178629 A CN 102178629A CN 2011100979333 A CN2011100979333 A CN 2011100979333A CN 201110097933 A CN201110097933 A CN 201110097933A CN 102178629 A CN102178629 A CN 102178629A
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Abstract
The invention discloses silybum marianum essential oil skin-care cream and a preparation method thereof. The formula of the silybum marianum essential oil skin-care cream comprises 5-15 parts of silybum marianum essential oil, 2-4 parts of glycerin monostearate (GMS), 6-13 parts of stearic acid, 4-9 parts of white Vaseline, 6-13 parts of liquid paraffin, 5-15 parts of glycerol, 10-18 parts of urea and 70-90 parts of deionized water. The preparation method of the silybum marianum essential oil skin-care cream comprises the following steps: respectively heating oil-phase raw materials and water-phase raw materials to 70-80 DEG C, and stirring at the temperature of 70-80 DEG C and the pressure of 1-1.3atm (standard atmospheric pressure) to obtain oil-phase material and water-phase material; stirring the oil-phase material and the water-phase material to form emulsion under heat insulation condition; and cooling to 45 DEG C, adding perfume materials, stirring, cooling to below 35 DEG C and finally discharging. The skin-care cream has the advantages of promoting metastasis, preserving heat, nourishing skin, and preventing frostbite and healing chaps without side effects, is particularly suitable for a person with dry and rough skin and skin peeling on hands and feet.
Description
Technical field
The present invention relates to a kind of cosmetics and preparation method thereof, is a kind of Herba Silybi mariani quintessence oil skin ﹠ complexion improving cream and preparation method thereof specifically.
Background technology
Be seen everywhere in the market at xerosis cutis, coarse, the peel cosmetics of phenomenon of skin brothers, though also can play effect, but preserve moisture, prevent and treat the weak effect of chapping, multipotency kept about 1 hour, and skin can recover former state again then, so just needed to smear repeatedly again, thereby increase the use amount of cosmetics, increased cost.And existing cosmetics much have side effect, and the somebody tends to occur buccal redness, flowing water, pruritus, dermatitis equivalent damage face or causes skin allergic reaction after using, and will make skin become even worse like this.
Herba Silybi mariani has another name called that water flies Phasiana, Silybum marianum Gaertn is a Compositae Silybum plant.Formal name used at school (Silybum marianumCL, Gaertn.) be biennial or the annual herb plant.Originate in the Mediterranean bank, on the western grassland in Asia, wild distribution is arranged also.All there are cultivation in existing Europe, Asia, Africa, South and North America.
Herba Silybi mariani oil claims " kangaroo oil " (Kangal oil) abroad, and edible and sunflower seed oil, safflower oil are similar.Units such as the 4th pharmaceutical factory, institute for drug control, Wuhan, botanical garden, Xi'an made animal toxicity experiment, nutritional test and edible through Guangzhou at home, proved nontoxicly, had higher nutritive value; Again through repeatedly many people for many years, edible through the new Cao Zhen resident in Dongtai city particularly, all no abnormal reaction.But owing to the system oil equipment that China is present is most with 95 type oil presses, material loading, discharge, remove impurity etc. are all manually carried out; Only process natural sedimentation of machine oil expression, oil product acid number height, the gastronomical process oil smoke is big, and edible flavor is poor; Machine presses cake and can not directly eat because of solvent is high through carrying the oil that reclaims after element is carried in plain workshop, can only sell as iundustrial oil, has caused very big waste.
Summary of the invention
Goal of the invention: in order to overcome the deficiencies in the prior art, the object of the present invention is to provide a kind ofly can enhance metabolism, preserving moisture and protecting skin, the antifreeze Herba Silybi mariani quintessence oil skin ﹠ complexion improving cream that more splits, has no side effect.
Another object of the present invention is to provide a kind of preparation method of Herba Silybi mariani quintessence oil skin ﹠ complexion improving cream.
Technical scheme: in order to solve the problems of the technologies described above, the technical solution adopted in the present invention is:
A kind of Herba Silybi mariani quintessence oil skin ﹠ complexion improving cream, comprise following component, the prescription of each component is as follows: 5-15 part Herba Silybi mariani quintessence oil, 2-4 part monoglyceride, 6-13 part stearic acid, 4-9 part white vaseline, 6-13 part white oil, 5-15 part glycerol, 10-18 part carbamide, 70-90 part deionized water more than are mass fraction.
Optimization formula is: according to the mass fraction, and 10 parts of Herba Silybi mariani quintessence oils, 3 parts of monoglycerides, 8 parts of stearic acid, 7 parts of white vaseline, 10 parts of white oils, 9 parts of glycerol, 15 parts of carbamide, 80 parts of deionized waters.
In order to solve above-mentioned another purpose, the technical solution adopted in the present invention is: the preparation method of described Herba Silybi mariani quintessence oil skin ﹠ complexion improving cream, this method comprises the steps:
(1) accurately take by weighing each component according to prescription, standby;
(2) Herba Silybi mariani quintessence oil, monoglyceride, stearic acid, white vaseline, white oil are joined in the oil phase stirred tank, are heated to 70-80 ℃, 1 to-1.3 standard atmosphere depress and 70-80 ℃ of insulated and stirred to the fusing, promptly obtain oil phase material;
(3) deionized water, glycerol, carbamide are joined in the water stirred tank, be warmed to 70-80 ℃, depress and, obtain the water material in the dissolving of 70-80 ℃ of insulated and stirred at 1 to-1.3 standard atmosphere;
(4) under the insulated and stirred oil phase material and water material are joined in the emulsifying still, depress and became the uniformly emulsify shape at 70-80 ℃ of insulated and stirred 10-20 minute at 1 to-1.3 standard atmosphere;
Allocate the spice of 0.1-0.3 mass parts when (5) being cooled to 45 ℃ then into and depress stirring 5-10 minute at 1 to-1.3 standard atmosphere, be cooled to 35 ℃ again and obtain semi-finished product with bottom discharge, semi-finished product promptly obtain described Herba Silybi mariani quintessence oil skin ﹠ complexion improving cream through after the assay was approved.
The Herba Silybi mariani quintessence oil is to obtain the Herba Silybi mariani crude oil through the twice pressing cold-press from Compositae Silybum plant seed among the present invention, and the Herba Silybi mariani crude oil obtains the Herba Silybi mariani quintessence oil by refine again.
Wherein, the Herba Silybi mariani quintessence oil contains up to the linoleic plus oleic acid more than 80%, and linoleic acid is that human body can not synthesize.Discover that cholesterol must could turn round and metabolism in vivo normally with after linoleic acid combines.If the shortage linoleic acid, cholesterol will combine with some satisfied fatty acid, and dysbolismus takes place, and under deposition on the blood vessel wall, progressively forms atherosclerosis, causes cardiovascular and cerebrovascular disease.Linoleic acid is unique essential fatty acid of generally acknowledging.Extremely paying attention to because linoleic acid can reduce blood cholesterol levels, and prevention of arterial is atherosis, can play the softening skin blood capillary, promote skin metabolism, is the desirable material of beauty and skin care.
Contained unsaturated fatty acids such as linoleic plus oleic acid in the Herba Silybi mariani quintessence oil are drying oil preferably, iodine value higher (93.12～127.5%), and it has good moisture retention and durability, and is long-acting obviously to the moisturizing effect of skin.
Also contain silymarin in the Herba Silybi mariani quintessence oil, the phenolic hydroxyl group of silymarin provides hydrogen atom and powerful antioxidation is arranged.They have the free radical of removing characteristic, and the anti peroxidation of lipid activity is directly removed active oxygen, and to anti peroxidation of lipid, keeping flowability of cell membranes has obvious effect to removal skin keratin, wrinkle removing stricture of vagina, defying age.
Also contain rich in amino acid, vitamin and abundant trace element such as Fe, Se in the Herba Silybi mariani quintessence oil, obvious to skin nourishing effect.
Beneficial effect: compared with prior art, advantage of the present invention is: owing to adopted the Herba Silybi mariani quintessence oil, contain unsaturated fatty acid more than 80% and an amount of aminoacid, trace element and vitamin in the Herba Silybi mariani quintessence oil, can improve the circulation of subcutaneous blood capillary, promote the metabolism of human skin cell's tissue, have powerful oxidation resistance and enhancing immunity effect; Carbamide has the effect of removing the epiderm skin horny layer and keeping skin moisturizing.Thereby goods had enhance metabolism, preserving moisture and protecting skin, antifreezely more split; Can effectively prevent chapping, prevent chilblain, anti peroxidation of lipid, radioprotective, removing free radical, antidotal health care.Be particularly suitable for xerosis cutis, coarse, the people of skin brothers decortication uses, and can make the long-term maintenance of skin soft and moist careful, and be free from side effects.Adopt this preparation method to make skin ﹠ complexion improving cream Herba Silybi mariani quintessence oil and other skin protection raw materials are fully synthetic, thereby improve the utilization rate of Herba Silybi mariani quintessence oil.
The specific embodiment
The present invention is further described below by specific embodiment; should be pointed out that for the person of ordinary skill of the art, under the prerequisite that does not break away from the principle of the invention; can also make some modification and improvement, these also should be considered as belonging to protection scope of the present invention.
Embodiment 1: according to the mass fraction, accurately taking by weighing 10 parts of Herba Silybi mariani quintessence oils, 3 parts of monoglycerides, 8 parts of stearic acid, 7 parts of white vaseline, 10 parts of white oils joins in the oil phase stirred tank, be heated to 70-80 ℃, and depress at 70-80 ℃, 1 to-1.3 standard atmosphere and to stir fusing in 5-15 minute and obtain oil phase material; Accurately take by weighing 9 parts of glycerol, 15 parts of carbamide, 80 parts of deionized waters and join in the water stirred tank, be warmed to 70-80 ℃ and depress at 1 to-1.3 standard atmosphere and to stir dissolving in 5-10 minute; Under the insulated and stirred oil phase material and water material are joined in the emulsifying still, depress 70-80 ℃ of insulated and stirred 10-20 minute one-tenth uniformly emulsify shape at 1 to-1.3 standard atmosphere, allocate the spice of 0.1 mass parts when being cooled to 45 ℃ then into and depress stirring 5-10 minute at 1 to-1.3 standard atmosphere, be cooled to 35 ℃ again with bottom discharge, store to storage tank, carry out the qualified back of inspection of semifinished product packing and promptly form Herba Silybi mariani quintessence oil skin ﹠ complexion improving cream finished product.
The Herba Silybi mariani quintessence oil is to obtain the Herba Silybi mariani crude oil through the twice pressing cold-press from Compositae Silybum plant seed among the present invention, and the Herba Silybi mariani crude oil obtains the Herba Silybi mariani quintessence oil by refine again.
Wherein, the Herba Silybi mariani quintessence oil contains up to the unsaturated fatty acids such as linoleic plus oleic acid more than 80%, also contains silymarin and rich in amino acid, vitamin and abundant trace element such as Fe, Se.
This Herba Silybi mariani quintessence oil skin ﹠ complexion improving cream is tested according to following standard: the guide rule of GB/T1.1-2000 cosmetic standardization; The basic regulations that GB/T 11-1993 standard is write; GB 5296.3 " Instructions for use of products of consumer interest cosmetics universal tag "; GB5296.3 Instructions for use of products of consumer interest cosmetics universal tag; The mensuration of the general test method pH value of GB/T 13531.1 cosmetics; QB/T 1684 cosmetics inspection rules; QB/T 1685 cosmetic product packaging external appearance requirements; The QB/T2286-1997 moisturizer; JJF 1070-2000 content of prepackaged goods with fixed net metering test rule; State Bureau of Technical Supervision makes quantification packing commodity metrological supervision regulation [1995] No. 43; Defend the method prison and send out [2002] No. 229 cosmetics health standards; Regulation among the GB/T 13531.1; 5.7 regulations among the QB/T 2286-1997; 6.1.1 regulation among the JJF 1070-2000; GB 5296.3; QB/T 1685.
Embodiment 2: according to the mass fraction, accurately take by weighing 5 parts of Herba Silybi mariani quintessence oils, 2 parts of monoglycerides, 6 parts of stearic acid, 4 parts of white vaseline, 6 parts of white oils and join in the oil phase stirred tank, be heated to 70-80 ℃ and depress at 1 to-1.3 standard atmosphere and to stir fusing in 5-15 minute; Accurately take by weighing 5 parts of glycerol, 10 parts of carbamide, 70 parts of deionized waters and join in the water stirred tank, be warmed to 70-80 ℃ and depress at 1 to-1.3 standard atmosphere and to stir dissolving in 5-10 minute; Under the insulated and stirred oil phase material and water material are joined in the emulsifying still, depress 70-80 ℃ of insulated and stirred 10-20 minute one-tenth uniformly emulsify shape at 1 to-1.3 standard atmosphere, allocate 0.2 part spice when being cooled to 45 ℃ then into and depress stirring 5-10 minute at 1 to-1.3 standard atmosphere, be cooled to 35 ℃ again with bottom discharge, store to storage tank, carry out the qualified back of inspection of semifinished product packing and promptly form Herba Silybi mariani quintessence oil skin ﹠ complexion improving cream finished product.
Embodiment 3: according to the mass fraction, accurately take by weighing 15 parts of Herba Silybi mariani quintessence oils, 4 parts of monoglycerides, 13 parts of stearic acid, 9 parts of white vaseline, 13 parts of white oils and join in the oil phase stirred tank, be heated to 70-80 ℃ and depress at 1 to-1.3 standard atmosphere and to stir fusing in 5-15 minute; Accurately take by weighing 15 parts of glycerol, 18 parts of carbamide, 90 parts of deionized waters and join in the water stirred tank, be warmed to 70-80 ℃ and depress at 1 to-1.3 standard atmosphere and to stir dissolving in 5-10 minute; Under the insulated and stirred oil phase material and water material are joined in the emulsifying still, depress 70-80 ℃ of insulated and stirred 10-20 minute one-tenth uniformly emulsify shape at 1 to-1.3 standard atmosphere, allocate 0.3 part spice when being cooled to 45 ℃ then into and depress stirring 5-10 minute at 1 to-1.3 standard atmosphere, be cooled to 35 ℃ again with bottom discharge, store to storage tank, carry out the qualified back of inspection of semifinished product packing and promptly form Herba Silybi mariani quintessence oil skin ﹠ complexion improving cream finished product.
Claims (5)
1. Herba Silybi mariani quintessence oil skin ﹠ complexion improving cream, it is characterized in that comprising following component, the prescription of each component is as follows: 5-15 part Herba Silybi mariani quintessence oil, 2-4 part monoglyceride, 6-13 part stearic acid, 4-9 part white vaseline, 6-13 part white oil, 5-15 part glycerol, 10-18 part carbamide, 70-90 part deionized water more than are mass fraction.
2. a kind of Herba Silybi mariani quintessence oil skin ﹠ complexion improving cream according to claim 1, it is characterized in that, according to the mass fraction, 10 parts of Herba Silybi mariani quintessence oils, 3 parts of monoglycerides, 8 parts of stearic acid, 7 parts of white vaseline, 10 parts of white oils, 9 parts of glycerol, 15 parts of carbamide, 80 parts of deionized waters.
3. the preparation method of the described Herba Silybi mariani quintessence oil of claim 1 skin ﹠ complexion improving cream is characterized in that this method comprises the steps:
(1) accurately take by weighing each component according to prescription, standby;
(2) Herba Silybi mariani quintessence oil, monoglyceride, stearic acid, white vaseline, white oil are joined in the oil phase stirred tank, are heated to 70-80 ℃, 1 to-1.3 standard atmosphere depress and 70-80 ℃ of insulated and stirred to the fusing, promptly obtain oil phase material;
(3) deionized water, glycerol, carbamide are joined in the water stirred tank, be warmed to 70-80 ℃, depress and, obtain the water material in the dissolving of 70-80 ℃ of insulated and stirred at 1 to-1.3 standard atmosphere;
(4) under the insulated and stirred oil phase material and water material are joined in the emulsifying still, depress and became the uniformly emulsify shape at 70-80 ℃ of insulated and stirred 10-20 minute at 1 to-1.3 standard atmosphere;
Allocate the spice of 0.1-0.3 weight portion when (5) being cooled to 45 ℃ then into and depress stirring 5-10 minute at 1 to-1.3 standard atmosphere, be cooled to 35 ℃ again and obtain semi-finished product with bottom discharge, semi-finished product promptly obtain described Herba Silybi mariani quintessence oil skin ﹠ complexion improving cream through check and packing after reaching the national cosmetic relevant criterion.
4. the preparation method of Herba Silybi mariani quintessence oil skin ﹠ complexion improving cream according to claim 3 is characterized in that, the time of stirring in the step (3) is 5-15 minute.
5. the preparation method of Herba Silybi mariani quintessence oil skin ﹠ complexion improving cream according to claim 3 is characterized in that, the time of stirring in the step (4) is 5-10 minute.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100979333A CN102178629B (en) | 2011-04-19 | 2011-04-19 | Silybum marianum essential oil skin-care cream and preparation method thereof |
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| CN2011100979333A CN102178629B (en) | 2011-04-19 | 2011-04-19 | Silybum marianum essential oil skin-care cream and preparation method thereof |
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| CN102178629A true CN102178629A (en) | 2011-09-14 |
| CN102178629B CN102178629B (en) | 2013-03-06 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108158912A (en) * | 2018-03-21 | 2018-06-15 | 镇江壹心生物工程技术有限公司 | A kind of milk thistle anti-acne repaiies trace gel and preparation method thereof |
| CN108721173A (en) * | 2018-08-17 | 2018-11-02 | 四川自然菲科技有限公司 | A kind of anti-aging type eye cream quickly absorbed |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4997649A (en) * | 1987-01-19 | 1991-03-05 | Parfums Rochas | Cosmetic and dermatological compositions including an extract of Silybum marianum rich in silymarine associated with essential fatty acids |
| JP2000290131A (en) * | 1999-04-07 | 2000-10-17 | Kanebo Ltd | Bleaching preparation |
| CZ294004B6 (en) * | 2001-03-12 | 2004-09-15 | Irel Spol. S R.O. | Therapeutic and cosmetic compositions for topic application |
| CN1761662A (en) * | 2003-03-25 | 2006-04-19 | 株式会社芳柯 | Composition for promoting production of type I collagen and/or elastin |
| FR2809008B1 (en) * | 2000-05-19 | 2006-07-28 | Sarl I De Zica | COSMETIC COMPOSITION COMPRISING CERAMIDES ASSOCIATED WITH SILYMARIN |
-
2011
- 2011-04-19 CN CN2011100979333A patent/CN102178629B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4997649A (en) * | 1987-01-19 | 1991-03-05 | Parfums Rochas | Cosmetic and dermatological compositions including an extract of Silybum marianum rich in silymarine associated with essential fatty acids |
| JP2000290131A (en) * | 1999-04-07 | 2000-10-17 | Kanebo Ltd | Bleaching preparation |
| FR2809008B1 (en) * | 2000-05-19 | 2006-07-28 | Sarl I De Zica | COSMETIC COMPOSITION COMPRISING CERAMIDES ASSOCIATED WITH SILYMARIN |
| CZ294004B6 (en) * | 2001-03-12 | 2004-09-15 | Irel Spol. S R.O. | Therapeutic and cosmetic compositions for topic application |
| CN1761662A (en) * | 2003-03-25 | 2006-04-19 | 株式会社芳柯 | Composition for promoting production of type I collagen and/or elastin |
Non-Patent Citations (3)
| Title |
|---|
| 《中国野生植物资源》 19911231 盛甦 水飞蓟油_一种很有开发利用价值的植物油 第15-18页 1-5 , 第4期 2 * |
| 《中国野生植物资源》 20051031 钱学射等人 值得开发与利用的水飞蓟油 第16-19页 1-5 , 第5期 2 * |
| 《食品研究与发展》 20070228 徐德峰等 国内水飞蓟资源利用现状与展望 第157-161页 1-5 第28卷, 第2期 2 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108158912A (en) * | 2018-03-21 | 2018-06-15 | 镇江壹心生物工程技术有限公司 | A kind of milk thistle anti-acne repaiies trace gel and preparation method thereof |
| CN108158912B (en) * | 2018-03-21 | 2020-08-28 | 胡莹姝 | Silybum marianum gel for removing acne and repairing scars and preparation method thereof |
| CN108721173A (en) * | 2018-08-17 | 2018-11-02 | 四川自然菲科技有限公司 | A kind of anti-aging type eye cream quickly absorbed |
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| CN102178629B (en) | 2013-03-06 |
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Application publication date: 20110914 Assignee: ZHENJIANG YIXIN BIOENGINEERING TECHNOLOGY CO.,LTD. Assignor: Dou Jianguo Contract record no.: 2014320000458 Denomination of invention: Silybum marianum essential oil skin-care cream and preparation method thereof Granted publication date: 20130306 License type: Exclusive License Record date: 20140528 |
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