CN102147990A - Loading device for simulating mechanical environment of vertebral body - Google Patents
Loading device for simulating mechanical environment of vertebral body Download PDFInfo
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- CN102147990A CN102147990A CN 201110054080 CN201110054080A CN102147990A CN 102147990 A CN102147990 A CN 102147990A CN 201110054080 CN201110054080 CN 201110054080 CN 201110054080 A CN201110054080 A CN 201110054080A CN 102147990 A CN102147990 A CN 102147990A
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- push rod
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Abstract
The invention relates to a loading device for simulating mechanical environment of a vertebral body, which comprises a rack, a bending and loading mechanism, a twisting mechanism and a culture room assembly, wherein the rack is formed by fixedly connecting a top plate, a middle plate, a bottom plate and two upright columns; the bending and loading mechanism comprises a stepping motor, a cylindrical cam, an eccentric shaft, an eccentric shaft support, a sliding rod, a mandril, a sliding rod screw, a positioning screw support, a mandril positioning screw, a spring positioning screw and a return spring; the cylindrical cam is provided with a spiral groove; the twisting mechanism comprises a twisting stepping motor, an object platform and a lifting platform; the culture room assembly comprises a culture room box body, a culture room box cover and a pressing block; and the pressing block acts on the loading object. The loading device has the advantages that the loading device can provide any two or three loading functions in axial compressing, twisting and lateral bending ways simultaneously, has variable regulating function and great economic practicability and can be used for test apparatuses for culturing engineered tissues such as intervertebral disc, cartilage and muscles and the biological and mechanical properties of the tissues.
Description
Technical field
The present invention relates to the bio-reactor in the biomedical engineering, particularly a kind of charger of simulating the centrum mechanical environment.
Background technology
Organizational project is meant principle and method with engineering science and life science, and preparation tissue and organ substitute to recover keeping or the improve function of human tissue organ, are rapid far-reaching biomedical engineering applications of development.At present, the tissue engineering skin product formally advances people's clinical practice, and organizational project bone, cartilage, skin and the nerve fiber of cultivation carried out experiment in the body.But, at present the organizational project distance be widely used in clinical, become social economy's new growth point and also have quite long road to walk.The organizational project bio-reactor is a similar environment in one of external achievements and body, quicken the system of cultured cell, tissue and even organ, can be widely used in substituting, make up, keeping or strengthen its function of organization as the organ defect patient, and field such as bio-pharmaceuticals.
By the various environmental quality mechanics under the body physiological condition of research cell tissue growth, biochemical environment etc., how study mechanics under the external environment, biochemical factor influences the dimensional culture and the functionalization process of cell, especially significant for the bionical charger of more rational design in the mechanics problem of soma.Backbone is the main shaft of human motion, and its activity has three-dimensional all around, rotation) and 6 degree of freedom.And centrum is as the important ingredient of backbone active unit, static along with human body or move different attitudes, six degree of freedom in the space also changes thereupon, mainly be subjected to axial compression, lateral thrust and twisting action, according to statistics the centrum stand under load normally compress, crooked and reverse between compound in twos.According to true physiological mechanics environment, the simulation of design charger is at the mechanics environment, and is most important to the functionalization structure of tissue, is to promote the constantly strong instrument of development of organizational project.
Powell, Courtney A. etc. has designed a kind of bio-reactor that skeletal muscle tissue is cultivated that can be used in, one section on skeletal muscle tissue support is fixing, one section links to each other with stepper motor, provide constant or periodicity tension and compression stress by stepper motor, the suffered tension and compression stress of support passes through sensor, and the tissue culture chamber can not rotate (Mechanical stimulation improves tissue-engineered human skeletal muscle, Am J Physiol, 2002; 282(5): 1557-1565).Adopt two series voltages pottery shifter as driving the source in " method and bio-reactor that a kind of low frequency high-amplitude overlapped high-frequency loads by a narrow margin " (China, NO. 200710303886.7) patent, can load the stack of cartilage double frequency.Many scholars have done a large amount of research for the centrum motion segment.(dissection of spinal motion and biomechanical basis, May the 26th in 2004 rolled up for the 5th phase by Chinese physical medicine and rehabilitation magazine, 308-310) mainly introduced the relation of spinal motion and stand under load, and the correlation of different loads and each institutional framework.(biomechanics under the different operating modes of applying three-dimensional finite element model research cervical vertebra changes clinical orthopaedics magazine, 2003 Dec; 6 (4), the mechanical environment of cervical vertebra that 294-296) adopted analysis of finite element method emulation.(biomechanics of artificial intervertebral disc art and mid-term clinical curative effect analysis, Chinese journal of orthopedics the 27 the 5th phase of volume of May in 2007,374-377) analyzed normal cervical vertebra and displacement artificial cervical dish in conjunction with clinical effectiveness after, mechanics link and structural variation between centrum and the interverbebral disc.
In sum, analysis and research are organized in the mechanics environment, and its true biomechanics environment of design simulation is most important for the constructing function histoorgan.So far, also do not reported a kind of loading system that can simulate centrum at the complicated mechanical environment of body, the periodicity axial compression of approximate physiological status was provided simultaneously, lateral bending and mechanical load such as reverse.
Summary of the invention
The present invention is directed to above-mentioned technical Analysis, according to biomechanics environment in the body of tissue growth, a kind of lateral bending that has is provided, reverse charger with the simulation centrum mechanical environment of vibrating function, this device swings by push rod and realizes bending, the dynamic load that realizes different decrements by adjustable eccentric cylinder cam and post rod mechanism, reverse to rotate and realize by driven by motor culturing room, this device can provide several different mechanics to load simultaneously, realize the coupling of different mechanical conditions, for tissue growth provides the biomechanics environment that is similar at body, also can carry out various Mechanics Performance Testings simultaneously.
Technical scheme of the present invention:
A kind of charger of simulating the centrum mechanical environment, comprise frame, bending and load maintainer, twist mechanism and culturing room's assembly, frame is fixedlyed connected with two root posts by top board, middle plate, base plate and is constituted, and is respectively equipped with perforation on top board and the middle plate, and base plate is provided with screw; Bending and load maintainer comprise stepper motor, cylindrical cam, two eccentric shafts, two eccentric shaft brackets, slide bar, push rod, the slide bar screw, two dog screw supports, the push rod dog screw, two spring dog screws and two back-moving springs, cylindrical cam is provided with spiral groove, two eccentric shafts are individually fixed in the two ends of cylindrical cam and are supported in two eccentric shaft brackets, excentric shaft near stepper motor output shaft one end is fixedlyed connected with stepper motor output shaft off-centre, the excentric shaft of the other end is connected with cylindrical cam and is provided with the adjusting lock-screw, and stepper motor and two eccentric shaft brackets are fixed with the top board of frame respectively; Be slidingly matched in the groove of slide bar its upper end embedding cylindrical cam when upright and with groove, slide bar is positioned at the groove of push rod upper end and breaks away from the groove of cylindrical cam the groove of push rod and cylindrical cam directly is slidingly matched when keeping flat, slide bar and push rod are fixed by the slide bar screw adjusted; Two dog screw supports are symmetricly set in the both sides of push rod and fix with the top board and the middle plate of frame respectively, and the push rod dog screw on two dog screw supports is regulated fixing with the locating slot of push rod both sides respectively; Two spring dog screws are individually fixed in the bottom of push rod and prop up with two dog screws puts up 90 degree angles, and an end of two back-moving springs is fixed with two spring dog screws respectively, and the top board of the other end and frame is fixed; Twist mechanism comprises and reverses stepper motor, article carrying platform and lifting table, article carrying platform is fixedlyed connected with the main shaft that reverses stepper motor, reverse stepper motor and lifting table is fixed, lifting table constitutes by screw on the framework soleplate and framework soleplate that liftable is regulated and is fixing; Culturing room's assembly comprises culturing room's box body, culturing room's lid and briquetting, culturing room's box body and article carrying platform are fixed, adding loading places in culturing room's box body, culturing room's lid separates because of the height that adds loading and briquetting supports with the culturing room box body, the push rod lower end closely contacts with briquetting, and briquetting passes center pit on culturing room's lid and acts on and add in the loading.
Principle of work of the present invention:
Stepper motor drives the cylindrical cam rotation, and slide bar is done linear reciprocating motion, and push rod is swung around dog screw, because terrestrial attraction and spring are regulated, adds loading and has certain pre compressed magnitude, by the existing crooked function of swing realization of push rod.Realize that the dynamic compression function mainly is by regulating the adjusting lock nut on the cylindrical cam, realize certain lift, slide bar being kept flat, regulate the lifting table height, push rod and cam closely cooperate, control motor speed, adjustment cam lift, and culture is realized the dynamic load of different decrements.Bottom motors drives the positive and negative rotation of culturing room by weighted platform, and culture is realized twisting action.
This device can provide axial compression simultaneously, reverse with lateral bending in any one or two or three plant multi-form acting in conjunction, realize the coupling of mechanical load, more near real physiological mechanics state in the body.Multi-functional cylindrical cam structure of the present invention in addition need not to dismantle the adjusting that can reach stroke, convenient and time-saving (referring to the patent No. 201019102005: the method for adjusting lift range of eccentric mechanism and the eccentric mechanism of adopting said method).The pendulum angle of push rod can be regulated by dog screw in addition, and simultaneously by the rotating angle and the speed of control step motor, the mechanical load that provides multiple variable to integrate helps testing contrast.This device can provide axial push-pull simultaneously, reverse with lateral bending in the acting in conjunction of two or three load forms arbitrarily, realize the coupling of mechanical load, more near real physiological mechanics state in the body.Also can realize the vibration of different frequency and amplitude by this device, study the influence to tissue growth of different amplitude-frequencies by biological test.
Superiority of the present invention: 1) can provide axial push-pull simultaneously, reverse with lateral bending in the arbitrarily acting in conjunction of two or three load forms, realize the coupling of mechanical load, more near real physiological mechanics state in the body.2) this system has variable regulatory function preferably, and the load of different sizes can be provided, and can design dependent variable, independent variable carries out the biology control test, and the comparative analysis different loads is to the influence of tissue growth, the validity that demo plant loads.3) loading system of the present invention is a kind of concrete but infinite enforcement power, not only can be used for cultivating engineering tissues such as interverbebral disc, cartilage, muscle, can also have bigger economic and practical as the biology of testing engineering tissue and the test apparatus of mechanical property.
Description of drawings
Fig. 1 is the structural representation of charger of the present invention.
Fig. 2 is a charger A-A cutaway view Amplified image of the present invention.
Fig. 3 for charger of the present invention etc. the axle side attempt.
Among the figure: 1. plate 3. base plate 4-I, 4-II in the top board 2.. column 5. stepper motors
6. cylindrical cam 7-I, 7-II. excentric shaft 8-I, 8-II. eccentric shaft bracket 9. slide bars
10. push rod 11. slide bar screw 12-I, 12-II. dog screw support 13-I, 13-II. push rod dog screw 14-I, 14-II. spring dog screw 15-I, 15-II. back-moving spring 16. is regulated lock-screws 17. and is reversed stepper motor 18. article carrying platforms 19. lifting tables 20. culturing room's box bodys
21. culturing room's lid 22. adds loading 23. briquetting 24-I, 24-II. screw.
Embodiment
Embodiment:
Below in conjunction with accompanying drawing loading system of the present invention is described in detail.
A kind of charger of simulating the centrum mechanical environment, comprise frame, bending and load maintainer, twist mechanism and culturing room's assembly, frame is fixedlyed connected with two root post 4-I, 4-II by top board 1, middle plate 2, base plate 3 and is constituted, be respectively equipped with perforation on top board 1 and the middle plate 2, base plate 3 is provided with screw; Bending and load maintainer comprise stepper motor 5, cylindrical cam 6, two eccentric shaft 7-I, the 7-II, two eccentric shaft bracket 8-I, the 8-II, slide bar 9, push rod 10, slide bar screw 11, two dog screw support 12-I, the 12-II, push rod dog screw 13, two spring dog screw 14-I, 14-II and two back-moving spring 15-I, the 15-II, cylindrical cam 6 is provided with spiral groove, two eccentric shaft 7-I, the 7-II is individually fixed in the two ends of cylindrical cam 6 and is supported in two eccentric shaft bracket 8-I, in the 8-II, excentric shaft 7-I near stepper motor 5 output shafts one end is fixedlyed connected with stepper motor 5 output shaft off-centre, the excentric shaft 7-II of the other end is connected with cylindrical cam 6 and is provided with regulates lock-screw 16, stepper motor 5 and two eccentric shaft bracket 8-I, the 8-II is fixing with the top board 1 of frame respectively; Be slidingly matched in the groove of slide bar 9 its upper end embedding cylindrical cam 6 when upright and with groove, slide bar 9 is positioned at the groove of push rod 10 upper ends and breaks away from the groove of cylindrical cam 6 push rod 10 and the groove of cylindrical cam 6 directly are slidingly matched when keeping flat, slide bar 9 is regulated fixing with push rod 10 by slide bar screw 11; Two dog screw support 12-I, 12-II are symmetricly set in the both sides of push rod 10 and fixing with the top board 1 and the middle plate 2 of frame respectively, and the push rod dog screw 13 on two dog screw support 12-I, the 12-II is regulated fixing with the locating slot of push rod 10 both sides respectively; Two spring dog screw 14-I, 14-II are individually fixed in the bottom of push rod 10 and become 90 to spend angles with two dog screw support 12-I, 12-II, one end of two back-moving spring 15-I, 15-II is fixed with two spring dog screw 14-I, 14-II respectively, and the top board 1 of the other end and frame is fixing; Twist mechanism comprises and reverses stepper motor 17, article carrying platform 18 and lifting table 19, article carrying platform 18 is fixedlyed connected with the main shaft that reverses stepper motor 17, it is fixing with lifting table 19 to reverse stepper motor 17, and lifting table 19 constitutes liftable adjusting and fixing by screw on the framework soleplate 3 and framework soleplate 3; Culturing room's assembly comprises culturing room's box body 20, culturing room's lid 21 and briquetting 23, culturing room's box body 20 is fixed by screw 24-I, 24-II with article carrying platform 18, adding loading 22 places in culturing room's box body 20, culturing room's lid 21 separates because of the height that adds loading 22 and briquetting 23 supports with culturing room box body 20, push rod 10 lower ends closely contact with briquetting 23, and briquetting passes center pit on culturing room's lid 21 and acts on and add in the loading 22.
Introduce below and introduce three kinds of principle of work that load form respectively: turn slide bar screw 11 is placed horizontally at slide bar 9 in push rod 10 grooves, regulate lifting table 19, push rod 10 and cylindrical cam 6 are closely cooperated, and make and add loading 22 certain (example 10%) decrement is arranged, change the eccentric throw of lift adjustable eccentric wheel mechanism by adjusting lock nut 16, realize the adjusting of different decrements, stepper motor 5 drives cylindrical cam 6 and rotates realization dynamic compression function.Twisting action, then by reverse stepper motor 17 drive culturing room's box bodys 20 just-despining, by regulating lifting table 19, add loading 22 certain decrement will be arranged, because it all has certain pressure up and down, culturing room's box body 20 rotates a certain angle, and will realize adding the twisting action of loading.
When slide bar 9 is positioned at vertical state, when the eccentric throw of lift adjustable eccentric wheel mechanism was non-zero simultaneously, stepper motor 5 rotations can realize the function of lateral bending and dynamic compression.If reverse stepper motor 17 rotations this moment, can realize adding the lateral bending dynamic compression of loading 22 and three kinds of loadings reversing.
Claims (1)
1. charger of simulating the centrum mechanical environment, it is characterized in that: comprise frame, bending and load maintainer, twist mechanism and culturing room's assembly, frame is fixedlyed connected with two root posts by top board, middle plate, base plate and is constituted, and is respectively equipped with perforation on top board and the middle plate, and base plate is provided with screw; Bending and load maintainer comprise stepper motor, cylindrical cam, two eccentric shafts, two eccentric shaft brackets, slide bar, push rod, the slide bar screw, two dog screw supports, the push rod dog screw, two spring dog screws and two back-moving springs, cylindrical cam is provided with spiral groove, two eccentric shafts are individually fixed in the two ends of cylindrical cam and are supported in two eccentric shaft brackets, excentric shaft near stepper motor output shaft one end is fixedlyed connected with stepper motor output shaft off-centre, the excentric shaft of the other end is connected with cylindrical cam and is provided with the adjusting lock-screw, and stepper motor and two eccentric shaft brackets are fixed with the top board of frame respectively; Be slidingly matched in the groove of slide bar its upper end embedding cylindrical cam when upright and with groove, slide bar is positioned at the groove of push rod upper end and breaks away from the groove of cylindrical cam the groove of push rod and cylindrical cam directly is slidingly matched when keeping flat, slide bar and push rod are fixed by the slide bar screw adjusted; Two dog screw supports are symmetricly set in the both sides of push rod and fix with the top board and the middle plate of frame respectively, and the push rod dog screw on two dog screw supports is regulated fixing with the locating slot of push rod both sides respectively; Two spring dog screws are individually fixed in the bottom of push rod and prop up with two dog screws puts up 90 degree angles, and an end of two back-moving springs is fixed with two spring dog screws respectively, and the top board of the other end and frame is fixed; Twist mechanism comprises and reverses stepper motor, article carrying platform and lifting table, article carrying platform is fixedlyed connected with the main shaft that reverses stepper motor, reverse stepper motor and lifting table is fixed, lifting table constitutes by screw on the framework soleplate and framework soleplate that liftable is regulated and is fixing; Culturing room's assembly comprises culturing room's box body, culturing room's lid and briquetting, culturing room's box body and article carrying platform are fixed, adding loading places in culturing room's box body, culturing room's lid separates because of the height that adds loading and briquetting supports with the culturing room box body, the push rod lower end closely contacts with briquetting, and briquetting passes center pit on culturing room's lid and acts on and add in the loading.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201110054080A CN102147990B (en) | 2011-03-08 | 2011-03-08 | Loading device for simulating mechanical environment of vertebral body |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201110054080A CN102147990B (en) | 2011-03-08 | 2011-03-08 | Loading device for simulating mechanical environment of vertebral body |
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| CN102147990A true CN102147990A (en) | 2011-08-10 |
| CN102147990B CN102147990B (en) | 2012-08-29 |
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Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102920523A (en) * | 2012-11-06 | 2013-02-13 | 王向阳 | Experimental animal rabbit lumbar disc shear stress loader |
| CN102980801A (en) * | 2012-12-27 | 2013-03-20 | 天津理工大学 | Loading device for intervertebral disc mechanics performance test |
| CN103266059A (en) * | 2013-05-31 | 2013-08-28 | 哈尔滨工业大学 | Mechanics loading type bioreactor capable of carrying out online measurement |
| CN105147494A (en) * | 2015-08-14 | 2015-12-16 | 西北工业大学 | Rodent limb long bone mechanics loading experimental device |
| CN105421199A (en) * | 2015-10-29 | 2016-03-23 | 安徽助成信息科技有限公司 | Mechanical type steady-state excitation device |
| CN105628601A (en) * | 2015-12-21 | 2016-06-01 | 天津理工大学 | Rolling load application control device for relevant cartilage experiment based on digital image |
| CN105699224A (en) * | 2016-04-08 | 2016-06-22 | 浙江大学城市学院 | Lumbar fatigue testing machine |
| CN106885675A (en) * | 2017-04-12 | 2017-06-23 | 浙江大学城市学院 | Lumbar vertebrae bone bursting fracture analog machine |
| CN109288615A (en) * | 2018-11-12 | 2019-02-01 | 天津理工大学 | Bone pulp cavity pretightning force loads monitoring device |
| CN109887393A (en) * | 2019-04-24 | 2019-06-14 | 上海市东方医院（同济大学附属东方医院） | Ring-type simulation device for degeneration of coccygeal intervertebral disc |
| CN111440717A (en) * | 2020-04-26 | 2020-07-24 | 华南理工大学 | Dynamic mechanical loading device based on orifice plate |
| CN113624476A (en) * | 2021-08-11 | 2021-11-09 | 浙江大学 | Spine circulation motion simulation testing machine |
| CN115372151A (en) * | 2022-10-24 | 2022-11-22 | 中国中医科学院望京医院(中国中医科学院骨伤科研究所) | Spinal column loading system and method |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101782102A (en) * | 2010-02-08 | 2010-07-21 | 天津理工大学 | Method for adjusting lift range of eccentric wheel mechanism and eccentric wheel mechanism using same |
-
2011
- 2011-03-08 CN CN201110054080A patent/CN102147990B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101782102A (en) * | 2010-02-08 | 2010-07-21 | 天津理工大学 | Method for adjusting lift range of eccentric wheel mechanism and eccentric wheel mechanism using same |
Non-Patent Citations (3)
| Title |
|---|
| 《IEEE》 20101231 Qiang Xu 等 A Dual-frequency Loading Device For Tissue Engineering Cartilage 全文 1 , * |
| 《中国医学装备》 20041130 张春秋等 一种用于骨组织工程生物反应器的设计 全文 1 第1卷, 第3期 * |
| 《中国组织工程研究与临床康复》 20100409 张春秋等 构建关节软骨的滚压加载装置 全文 1 第14卷, 第15期 * |
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102920523B (en) * | 2012-11-06 | 2014-09-10 | 王向阳 | Experimental animal rabbit lumbar disc shear stress loader |
| CN102920523A (en) * | 2012-11-06 | 2013-02-13 | 王向阳 | Experimental animal rabbit lumbar disc shear stress loader |
| CN102980801A (en) * | 2012-12-27 | 2013-03-20 | 天津理工大学 | Loading device for intervertebral disc mechanics performance test |
| CN103266059A (en) * | 2013-05-31 | 2013-08-28 | 哈尔滨工业大学 | Mechanics loading type bioreactor capable of carrying out online measurement |
| CN105147494A (en) * | 2015-08-14 | 2015-12-16 | 西北工业大学 | Rodent limb long bone mechanics loading experimental device |
| CN105147494B (en) * | 2015-08-14 | 2017-09-12 | 西北工业大学 | A kind of rodent long bone of limbs Mechanical loading experimental provision |
| CN105421199A (en) * | 2015-10-29 | 2016-03-23 | 安徽助成信息科技有限公司 | Mechanical type steady-state excitation device |
| CN105628601B (en) * | 2015-12-21 | 2018-06-08 | 天津理工大学 | A kind of rolling load for cartilage digital picture related experiment applies control device |
| CN105628601A (en) * | 2015-12-21 | 2016-06-01 | 天津理工大学 | Rolling load application control device for relevant cartilage experiment based on digital image |
| CN105699224A (en) * | 2016-04-08 | 2016-06-22 | 浙江大学城市学院 | Lumbar fatigue testing machine |
| CN106885675A (en) * | 2017-04-12 | 2017-06-23 | 浙江大学城市学院 | Lumbar vertebrae bone bursting fracture analog machine |
| CN109288615A (en) * | 2018-11-12 | 2019-02-01 | 天津理工大学 | Bone pulp cavity pretightning force loads monitoring device |
| CN109288615B (en) * | 2018-11-12 | 2024-02-23 | 天津理工大学 | Bone marrow cavity pretightening force loading monitoring device |
| CN109887393A (en) * | 2019-04-24 | 2019-06-14 | 上海市东方医院（同济大学附属东方医院） | Ring-type simulation device for degeneration of coccygeal intervertebral disc |
| CN111440717A (en) * | 2020-04-26 | 2020-07-24 | 华南理工大学 | Dynamic mechanical loading device based on orifice plate |
| CN113624476A (en) * | 2021-08-11 | 2021-11-09 | 浙江大学 | Spine circulation motion simulation testing machine |
| CN113624476B (en) * | 2021-08-11 | 2022-04-01 | 浙江大学 | Spine circulation motion simulation testing machine |
| CN115372151A (en) * | 2022-10-24 | 2022-11-22 | 中国中医科学院望京医院(中国中医科学院骨伤科研究所) | Spinal column loading system and method |
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