CN102920523B - Experimental animal rabbit lumbar disc shear stress loader - Google Patents
Experimental animal rabbit lumbar disc shear stress loader Download PDFInfo
- Publication number
- CN102920523B CN102920523B CN201210438551.7A CN201210438551A CN102920523B CN 102920523 B CN102920523 B CN 102920523B CN 201210438551 A CN201210438551 A CN 201210438551A CN 102920523 B CN102920523 B CN 102920523B
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- China
- Prior art keywords
- clamping device
- shear stress
- cushion cap
- intervertebral disc
- disc shear
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Abstract
The invention discloses an experimental animal rabbit lumbar disc shear stress loader which comprises a bracket, a first clamping device and a second clamping device. A U-shaped notch is opened on the bracket, a vertically arranged connection column is fixed on the top surface of the first clamping device, penetrates through the U-shaped notch from bottom to top and penetrates out of the top surface of the bracket, the connection column is provided with a thread portion, an adjusting nut is installed on the thread portion in a threaded mode and located in the U-shaped notch, a spring is arranged above the adjusting nut and sleeved on the connection column, and two ends of the spring abut against the top surface of the adjusting nut and the upper wall of the U-shaped notch respectively. According to the experimental animal rabbit lumbar disc shear stress loader, the first clamping device and the second clamping device can longitudinally and relatively be displaced by rotating the adjusting nut, so that a clamped animal lumbar disc generates shear stress, and stress research on lumbar disc shear stress is facilitated.
Description
Technical field
The present invention relates to experimental provision, be specifically related to laboratory animal rabbit lumbar intervertebral disc shear stress loader.
Background technology
Intervertebral disc is an important component part of spinal column, and its major function is absorb, cushion and transmit the suffered load of human body, and its existence simultaneously makes spinal column activity within the specific limits.But the regression of intervertebral disc tends to cause the dysfunction of spinal column even to lose, the intervertebral disc of part regression also can cause the spinal column degenerative disease such as prolapse of lumbar intervertebral disc, discogenic pain and cervical spondylosis, have a strong impact on patient's quality of life, caused huge financial burden to family and society.Therefore the research of carrying out relevant disease from this aspect of intervertebral disc degeneration be at present institute in the urgent need to, for this reason, need the mechanism of means understanding intervertebral disc degeneration by experiment.
The relation of load and intervertebral disc degeneration is nearest study hotspot always, research finds that the axial compression that exceeds physiological range can clearly cause the regression of intervertebral disc, there is thus scholar to propose to cause taking mechanical load factor as initiating agent the concept of intervertebral disc degeneration, be non-physiologic load induction intervertebral disc structure infringement and the reaction of a series of cell-mediated irreversibility of intervertebral disc, and these change the weakness due to Nutrition and Metabolism path, the variation at age, imperfection and the inherited genetic factors etc. of repair mechanism further deepened the regression of intervertebral disc.But the load in these researchs is often all too dull, nearly all only pay close attention to axial compression, and the suffered load of human spine is complicated known to us, comprise multiple ingredients, particularly shear stress such as compression, shearing to degeneration locomotor disease the research acting in recent years receive increasing concern.Have research to point out, excessive shear stress will cause the regression of articular cartilage to cause the generation of osteoarthritis.Because its top rake is large, carrying more shear stress with respect to other sections at human spine's lumbosacral segment, and this sections the most incident position of intervertebral disc degeneration just.Therefore in the research of intervertebral disc, also receive more and more concern for the relation of intervertebral disc degeneration and shear stress, research is found, differentiation, the growth of shear stress on intervertebral disc cells has very large impact, so, when research intervertebral disc, should consider in experimentation and correlation model manufacturing process and go using shear stress as an important factor.But, still there is no suitable intervertebral disc shear stress loader at present.
Summary of the invention
Technical problem to be solved by this invention is to solve problem how to explore the effect of shear stress to intervertebral disc degeneration.
In order to solve the problems of the technologies described above, the technical solution adopted in the present invention is to provide a kind of laboratory animal rabbit lumbar intervertebral disc shear stress loader, comprise support, the first clamping device and the second clamping device, the top of a side of described support has a U-shaped breach, described the first clamping device and the second clamping device are arranged on the bottom surface of described support in parallel to each other, on the end face of described the first clamping device, be fixed with a joint pin vertically arranging, described joint pin runs through described U-shaped breach from bottom to top and passes from the end face of described support, described joint pin has threaded portion, and on described threaded portion, be screwed with an adjusting nut, described adjusting nut is positioned at described U-shaped breach, the top of described adjusting nut arranges a spring, described spring housing is contained on described joint pin and two ends offset with the end face of described adjusting nut and the upper wall of described U-shaped breach respectively.
In such scheme, described the first clamping device and described the second clamping device include the first clamping limb and the second clamping limb that upper end is articulated and connected, the lower end of described the first clamping limb and described the second clamping limb is a hinged claw respectively, two described claws are oppositely arranged, and described the first clamping limb and described the second clamping limb regulate angle between the two by adjusting device.
In such scheme, described adjusting device comprises adjusting bolt and nut, and described adjusting bolt runs through described the first clamping limb and described the second clamping limb; Described nut spiral shell is contained in the external part of described adjusting bolt.
In such scheme, on the bottom surface of described support, there is two the first cushion caps that be arranged in parallel and the second cushion cap, described the first clamping device is arranged on the bottom surface of described the first cushion cap, and described the second clamping device is arranged on the bottom surface of described the second cushion cap.
In such scheme, described the first cushion cap has first through hole vertically arranging, and described joint pin is installed in described the first through hole and with described first clamping device is threaded fixing after passing described the first cushion cap downwards.
In such scheme, described the second cushion cap has second through hole longitudinally arranging, and is fixed with a rotating shaft on the end face of described the second clamping device, and described rotating shaft is rotated and is arranged in described the second through hole.
In such scheme, the upper end of described rotating shaft upwards passes after described the second cushion cap spacing by jump ring.
In such scheme, the upper end of described rotating shaft is fixed by nut after upwards passing described the second cushion cap, on the end face of described the second clamping device, along being circumferentially laid with multiple tooth bars that distribute radially, the bottom surface of described the second cushion cap is provided with the teeth groove matching with described tooth bar.
The present invention, just can make the first clamping device lifting by rotation adjusting nut, thereby produce longitudinal relative displacement with the second clamping device, make the animal lumbar intervertebral disc of first, second clamping device clamping produce shear stress, be convenient to the stressed research of intervertebral disc shear stress.
Brief description of the drawings
Fig. 1 is structural representation of the present invention;
Fig. 2 is the structural representation of clamping device.
Detailed description of the invention
Below in conjunction with accompanying drawing, the present invention is described in detail.
As shown in Figure 1, laboratory animal rabbit lumbar intervertebral disc shear stress loader provided by the invention, comprises support 1, the first clamping device 21 and the second clamping device 22.The first clamping device 21 and the second clamping device 22 structures are basic identical, and are arranged in parallel on the bottom surface of support 1.
On the bottom surface of support 1, there is the first cushion cap 11 and the second cushion cap 12, the second clamping device 22 is arranged on the bottom surface of the second cushion cap 12, the top of support 1 is provided with a U-shaped breach 13, the lower end of joint pin 3 is fixed with the upper end of the first clamping device 21 through U-shaped breach 13 and from the bottom surface of the first cushion cap 11 passes from top to bottom, the upper end of joint pin 3 upwards passes the end face of support 1, joint pin 3 has threaded portion 31, and on threaded portion 31, be screwed with an adjusting nut 4, adjusting nut 4 is positioned at U-shaped breach 13, the top of adjusting nut 4 arranges a spring 5, spring 5 is sleeved on joint pin 3 and spring 5 upper, lower two ends offset with the upper wall of adjusting nut 4 and U-shaped breach 13 respectively, spring 5 is for generation of shearing force, adjusting nut 4 can regulating spring 5 elastic force size.Specifically, upwards rotate adjusting nut 4, spring 5 is compressed, so the elastic force of spring 5 passes to joint pin 3 by adjusting nut 4,3 of the joint pins elastic force by spring 5 passes to the first clamping device 21, thereby produces shearing force.
Refer to again Fig. 2, the first clamping device 21 and the second clamping device 22 include the first clamping limb 23 and the second clamping limb 24 that are oppositely arranged, the lower end of the first clamping limb 23 and the second clamping limb 24 is a hinged claw 25 respectively, two claws 25 are oppositely arranged, be used for buckle animal vertebral body, the upper articulation of the first clamping limb 23 and the second clamping limb 24, and regulate angle between the two by adjusting device, thereby change the distance between two claws 25, clamp or unclamp animal vertebral body.
In the present embodiment, adjusting device comprises adjusting bolt 26 and nut 27, adjusting bolt 26 runs through the first clamping limb 23 and the second clamping limb 24 is rear and nut 27 spiral shells dresses are fixing, just can change the angle between the first clamping limb 23 and the second clamping limb 24 by rotating nut 27, closely change the distance between two claws 25.
According to concrete practical application, the present invention has proposed following two kinds of detailed description of the invention targetedly.
Embodiment 1.
The first cushion cap 11 has first through hole vertically arranging, and joint pin 3 is installed in the first through hole and passes the first cushion cap 11 downwards and is threaded fixing with the first clamping device 21 afterwards.The second cushion cap 12 has second through hole longitudinally arranging, and is fixed with a rotating shaft on the end face of the second clamping device 22, and rotating shaft is rotated and is arranged in the second through hole, and it is rear spacing by jump ring that the upper end of rotating shaft upwards passes the second cushion cap 12.In this detailed description of the invention, the second clamping device 22 can freely rotate around the axis of the second cushion cap 12, like this, and in the time that the first clamping device 21 produces shearing force, its produced simultaneously torsion can be digested by the second clamping device 22, thus the convenient research to pure shear shear force.
Embodiment 2.
The difference of the present embodiment and embodiment 1 is, the upper end of rotating shaft is fixed by nut after upwards passing the second cushion cap 12, on the end face of the second clamping device 22, along being circumferentially laid with multiple tooth bars that distribute radially, the bottom surface of the second cushion cap 12 is provided with the teeth groove matching with described tooth bar.In this detailed description of the invention, the second clamping device 22 is freely to rotate around the axis of the second cushion cap 12, therefore, is applicable to research because the first clamping device 21 produces shearing force, produce again the situation of torsion simultaneously, that is to say that torsion can not ignore.In addition, unclamping nut can make the second clamping device 22 leave the second cushion cap 12, rotate again 22 of the second clamping devices and can change its angle, finally by screwing nut check, make the second clamping device 22 and the second cushion cap 12 interlock again, can apply artificially in this way torsion, conveniently carry out the research of shearing force+torsion.
Because the second clamping device 22 and the second cushion cap 12 are by tooth, groove interlock, therefore, the torsion applying is controllable, is convenient to carry out quantitative study.
The present invention is not limited to above-mentioned preferred forms, and anyone should learn the structural change of making under enlightenment of the present invention, and every have identical or close technical scheme with the present invention, within all falling into protection scope of the present invention.
Claims (8)
1. laboratory animal rabbit lumbar intervertebral disc shear stress loader, is characterized in that, comprising:
Support, the top of an one side has a U-shaped breach;
The first clamping device and the second clamping device, be arranged in parallel to each other on the bottom surface of described support, on the end face of described the first clamping device, be fixed with a joint pin vertically arranging, described joint pin runs through described U-shaped breach from bottom to top and passes from the end face of described support, described joint pin has threaded portion, and on described threaded portion, be screwed with an adjusting nut, described adjusting nut is positioned at described U-shaped breach, the top of described adjusting nut arranges a spring, described spring housing is contained on described joint pin and two ends offset with the end face of described adjusting nut and the upper wall of described U-shaped breach respectively.
2. laboratory animal rabbit lumbar intervertebral disc shear stress loader as claimed in claim 1, it is characterized in that, described the first clamping device and described the second clamping device include the first clamping limb and the second clamping limb that upper end is articulated and connected, the lower end of described the first clamping limb and described the second clamping limb is a hinged claw respectively, two described claws are oppositely arranged, and described the first clamping limb and described the second clamping limb regulate angle between the two by adjusting device.
3. laboratory animal rabbit lumbar intervertebral disc shear stress loader as claimed in claim 2, is characterized in that, described adjusting device comprises:
Adjusting bolt, runs through described the first clamping limb and described the second clamping limb;
Nut, spiral shell is contained in the external part of described adjusting bolt.
4. laboratory animal rabbit lumbar intervertebral disc shear stress loader as claimed in claim 3, it is characterized in that, on the bottom surface of described support, there is two the first cushion caps that be arranged in parallel and the second cushion cap, described the first clamping device is arranged on the bottom surface of described the first cushion cap, and described the second clamping device is arranged on the bottom surface of described the second cushion cap.
5. laboratory animal rabbit lumbar intervertebral disc shear stress loader as claimed in claim 4, it is characterized in that, described the first cushion cap has first through hole vertically arranging, and described joint pin is installed in described the first through hole and with described first clamping device is threaded fixing after passing described the first cushion cap downwards.
6. laboratory animal rabbit lumbar intervertebral disc shear stress loader as claimed in claim 4, it is characterized in that, described the second cushion cap has second through hole longitudinally arranging, and is fixed with a rotating shaft on the end face of described the second clamping device, and described rotating shaft is rotated and is arranged in described the second through hole.
7. laboratory animal rabbit lumbar intervertebral disc shear stress loader as claimed in claim 6, is characterized in that, the upper end of described rotating shaft upwards passes after described the second cushion cap spacing by jump ring.
8. laboratory animal rabbit lumbar intervertebral disc shear stress loader as claimed in claim 6, it is characterized in that, the upper end of described rotating shaft is fixed by nut after upwards passing described the second cushion cap, on the end face of described the second clamping device, along being circumferentially laid with multiple tooth bars that distribute radially, the bottom surface of described the second cushion cap is provided with the teeth groove matching with described tooth bar.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210438551.7A CN102920523B (en) | 2012-11-06 | 2012-11-06 | Experimental animal rabbit lumbar disc shear stress loader |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210438551.7A CN102920523B (en) | 2012-11-06 | 2012-11-06 | Experimental animal rabbit lumbar disc shear stress loader |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102920523A CN102920523A (en) | 2013-02-13 |
| CN102920523B true CN102920523B (en) | 2014-09-10 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210438551.7A Expired - Fee Related CN102920523B (en) | 2012-11-06 | 2012-11-06 | Experimental animal rabbit lumbar disc shear stress loader |
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| Country | Link |
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| CN (1) | CN102920523B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106073932A (en) * | 2016-05-29 | 2016-11-09 | 中国人民解放军海军总医院 | Lumbar Intervertebral Disc Degeneration animal model biomechanics molding machine |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104885961B (en) * | 2015-05-11 | 2017-03-29 | 同济大学 | A kind of laboratory animal caudal vertebra rocking equipment and its application |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102147990A (en) * | 2011-03-08 | 2011-08-10 | 天津理工大学 | Loading device for simulating mechanical environment of vertebral body |
| CN102178567A (en) * | 2011-04-21 | 2011-09-14 | 四川大学华西医院 | Rat spine distracting device |
| CN102743236A (en) * | 2012-07-30 | 2012-10-24 | 中国科学院自动化研究所 | Rabbit spine curving device for experiment |
| CN202920403U (en) * | 2012-11-06 | 2013-05-08 | 王向阳 | Shear stress loader for lumbar disc of experimental animal rabbit |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8668719B2 (en) * | 2009-03-30 | 2014-03-11 | Simpirica Spine, Inc. | Methods and apparatus for improving shear loading capacity of a spinal segment |
-
2012
- 2012-11-06 CN CN201210438551.7A patent/CN102920523B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102147990A (en) * | 2011-03-08 | 2011-08-10 | 天津理工大学 | Loading device for simulating mechanical environment of vertebral body |
| CN102178567A (en) * | 2011-04-21 | 2011-09-14 | 四川大学华西医院 | Rat spine distracting device |
| CN102743236A (en) * | 2012-07-30 | 2012-10-24 | 中国科学院自动化研究所 | Rabbit spine curving device for experiment |
| CN202920403U (en) * | 2012-11-06 | 2013-05-08 | 王向阳 | Shear stress loader for lumbar disc of experimental animal rabbit |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106073932A (en) * | 2016-05-29 | 2016-11-09 | 中国人民解放军海军总医院 | Lumbar Intervertebral Disc Degeneration animal model biomechanics molding machine |
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| CN102920523A (en) | 2013-02-13 |
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