CN102920523A - Experimental animal rabbit lumbar disc shear stress loader - Google Patents
Experimental animal rabbit lumbar disc shear stress loader Download PDFInfo
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- CN102920523A CN102920523A CN2012104385517A CN201210438551A CN102920523A CN 102920523 A CN102920523 A CN 102920523A CN 2012104385517 A CN2012104385517 A CN 2012104385517A CN 201210438551 A CN201210438551 A CN 201210438551A CN 102920523 A CN102920523 A CN 102920523A
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- clamping device
- shear stress
- cushion cap
- intervertebral disc
- disc shear
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Abstract
The invention discloses an experimental animal rabbit lumbar disc shear stress loader which comprises a bracket, a first clamping device and a second clamping device. A U-shaped notch is opened on the bracket, a vertically arranged connection column is fixed on the top surface of the first clamping device, penetrates through the U-shaped notch from bottom to top and penetrates out of the top surface of the bracket, the connection column is provided with a thread portion, an adjusting nut is installed on the thread portion in a threaded mode and located in the U-shaped notch, a spring is arranged above the adjusting nut and sleeved on the connection column, and two ends of the spring abut against the top surface of the adjusting nut and the upper wall of the U-shaped notch respectively. According to the experimental animal rabbit lumbar disc shear stress loader, the first clamping device and the second clamping device can longitudinally and relatively be displaced by rotating the adjusting nut, so that a clamped animal lumbar disc generates shear stress, and stress research on lumbar disc shear stress is facilitated.
Description
Technical field
The present invention relates to experimental provision, be specifically related to laboratory animal rabbit lumbar intervertebral disc shear stress loader.
Background technology
Intervertebral disc is an important component part of spinal column, and its major function is to absorb, cushion and the suffered load of transmission human body, and simultaneously its existence is so that spinal column can be movable within the specific limits.Yet the regression of intervertebral disc tends to cause dysfunction even the forfeiture of spinal column, the intervertebral disc of part regression also can cause the spinal column degenerative disease such as prolapse of lumbar intervertebral disc, discogenic pain and cervical spondylosis, have a strong impact on Quality of Life, caused huge financial burden for family and society.Therefore the research of carrying out relevant disease from this aspect of intervertebral disc degeneration be at present institute in the urgent need to, for this reason, need the by experiment mechanism of means understanding intervertebral disc degeneration.
The relation of load and intervertebral disc degeneration is nearest study hotspot always, the axial compression that research finds to exceed physiological range can clearly cause the regression of intervertebral disc, there is thus the scholar to propose to cause take the mechanical load factor as initiating agent the concept of intervertebral disc degeneration, the non-physiologic load that is intervertebral disc is induced intervertebral disc structure infringement and the reaction of a series of cell-mediated irreversibility, and these change because the weakness of Nutrition and Metabolism path, the regression of intervertebral disc is further deepened in the variation at age, the imperfection of repair mechanism and inherited genetic factors etc.But the load in these researchs is often all too dull, nearly all only pay close attention to axial compression, and the suffered load of human spine is complicated known to us, comprise a plurality of ingredients, particularly shear stress such as compression, shearing to the degeneration locomotor disease the research that acts in recent years receive increasing concern.There is research to point out that excessive shear stress will cause the regression of articular cartilage to cause the generation of osteoarthritis.Because its top rake is large, carrying more shear stress with respect to other sections at human spine's lumbosacral segment, and this sections the most incident position of intervertebral disc degeneration just.Therefore the relation for intervertebral disc degeneration and shear stress also receives more and more the concern in the research of intervertebral disc, research is found, shear stress has very large impact to differentiation, the growth of intervertebral disc cells, so, should consider shear stress in experimentation and the correlation model manufacturing process as an important factor during research intervertebral disc and go.But, still do not have suitable intervertebral disc shear stress loader at present.
Summary of the invention
Technical problem to be solved by this invention is to solve how to explore shear stress to the problem of the effect of intervertebral disc degeneration.
In order to solve the problems of the technologies described above, the technical solution adopted in the present invention provides a kind of laboratory animal rabbit lumbar intervertebral disc shear stress loader, comprise support, the first clamping device and the second clamping device, the top of a side of described support has a U-shaped breach, described the first clamping device and the second clamping device are arranged on the bottom surface of described support in parallel to each other, be fixed with a joint pin that vertically arranges on the end face of described the first clamping device, described joint pin runs through described U-shaped breach from bottom to top and passes from the end face of described support, described joint pin has the threaded portion, and be screwed with an adjusting nut on the described threaded portion, described adjusting nut is positioned at described U-shaped breach, the top of described adjusting nut arranges a spring, and described spring housing is contained on the described joint pin and two ends offset with the end face of described adjusting nut and the upper wall of described U-shaped breach respectively.
In such scheme, described the first clamping device and described the second clamping device include the first clamping limb and the second clamping limb that the upper end is articulated and connected, the lower end of described the first clamping limb and described the second clamping limb is a hinged claw respectively, two described claws are oppositely arranged, and described the first clamping limb and described the second clamping limb are regulated angle between the two by adjusting device.
In such scheme, described adjusting device comprises adjusting bolt and nut, and described adjusting bolt runs through described the first clamping limb and described the second clamping limb; Described nut spiral shell is contained in the external part of described adjusting bolt.
In such scheme, have two the first cushion caps that be arranged in parallel and the second cushion cap on the bottom surface of described support, described the first clamping device is arranged on the bottom surface of described the first cushion cap, and described the second clamping device is arranged on the bottom surface of described the second cushion cap.
In such scheme, described the first cushion cap has first through hole that vertically arranges, and described joint pin is installed in described the first through hole and with described first clamping device is threaded fixing after passing described the first cushion cap downwards.
In such scheme, described the second cushion cap has second through hole that vertically arranges, and is fixed with a rotating shaft on the end face of described the second clamping device, and described rotating shaft is rotated and is arranged in described the second through hole.
In such scheme, the upper end of described rotating shaft upwards passes behind described the second cushion cap spacing by jump ring.
In such scheme, the upper end of described rotating shaft is fixed by nut after upwards passing described the second cushion cap, along circumferentially being laid with a plurality of tooth bars that distribute radially, the bottom surface of described the second cushion cap is provided with the teeth groove that matches with described tooth bar on the end face of described the second clamping device.
The present invention, just can make the first clamping device lifting by the rotation adjusting nut, thereby produce longitudinally relative displacement with the second clamping device, make the animal lumbar intervertebral disc of first, second clamping device clamping produce shear stress, be convenient to the stressed research of intervertebral disc shear stress.
Description of drawings
Fig. 1 is structural representation of the present invention;
Fig. 2 is the structural representation of clamping device.
The specific embodiment
Below in conjunction with accompanying drawing the present invention is made detailed explanation.
As shown in Figure 1, laboratory animal rabbit lumbar intervertebral disc shear stress loader provided by the invention comprises support 1, the first clamping device 21 and the second clamping device 22.The first clamping device 21 and the second clamping device 22 structures are basic identical, and are arranged in parallel on the bottom surface of support 1.
Have the first cushion cap 11 and the second cushion cap 12 on the bottom surface of support 1, the second clamping device 22 is arranged on the bottom surface of the second cushion cap 12, the top of support 1 is provided with a U-shaped breach 13, the lower end of joint pin 3 pass U-shaped breach 13 from top to bottom and pass from the bottom surface of the first cushion cap 11 after fix with the upper end of the first clamping device 21, the upper end of joint pin 3 upwards passes the end face of support 1, joint pin 3 has threaded portion 31, and be screwed with an adjusting nut 4 on the threaded portion 31, adjusting nut 4 is positioned at U-shaped breach 13, the top of adjusting nut 4 arranges a spring 5, spring 5 is sleeved on the joint pin 3 and spring 5 upper, lower two ends offset with the upper wall of adjusting nut 4 and U-shaped breach 13 respectively, spring 5 is for generation of shearing force, the size that adjusting nut 4 can regulating spring 5 elastic force.Specifically, upwards rotate adjusting nut 4, make spring 5 compressions, so the elastic force of spring 5 passes to joint pin 3 by adjusting nut 4,3 elastic force with spring 5 of joint pin pass to the first clamping device 21, thereby produce shearing force.
See also again Fig. 2, the first clamping device 21 and the second clamping device 22 include the first clamping limb 23 and the second clamping limb 24 that is oppositely arranged, the lower end of the first clamping limb 23 and the second clamping limb 24 is a hinged claw 25 respectively, two claws 25 are oppositely arranged, be used for buckle the animal vertebral body, the upper articulation of the first clamping limb 23 and the second clamping limb 24, and regulate angle between the two by adjusting device, thereby change two distances between the claw 25, clamp or unclamp the animal vertebral body.
In the present embodiment, adjusting device comprises adjusting bolt 26 and nut 27, adjusting bolt 26 runs through behind the first clamping limb 23 and the second clamping limb 24 and nut 27 spiral shells dress is fixed, just can change angle between the first clamping limb 23 and the second clamping limb 24 by rotating nut 27, near and change two distances between the claw 25.
According to concrete practical application, the present invention has proposed following two kinds of specific embodiment targetedly.
Embodiment 1.
The first cushion cap 11 has first through hole that vertically arranges, and joint pin 3 is installed in the first through hole and passes the first cushion cap 11 downwards and is threaded fixing with the first clamping device 21 afterwards.The second cushion cap 12 has second through hole that vertically arranges, and is fixed with a rotating shaft on the end face of the second clamping device 22, and rotating shaft is rotated and is arranged in the second through hole, and it is rear spacing by jump ring that the upper end of rotating shaft upwards passes the second cushion cap 12.In this specific embodiment, the second clamping device 22 can freely rotate around the axis of the second cushion cap 12, like this, and when the first clamping device 21 produces shearing force, its produced simultaneously torsion can be digested by the second clamping device 22, thus convenient research to pure shear shear force.
Embodiment 2.
The difference of present embodiment and embodiment 1 is, the upper end of rotating shaft is fixed by nut after upwards passing the second cushion cap 12, along circumferentially being laid with a plurality of tooth bars that distribute radially, the bottom surface of the second cushion cap 12 is provided with the teeth groove that matches with described tooth bar on the end face of the second clamping device 22.In this specific embodiment, the second clamping device 22 is freely to rotate around the axis of the second cushion cap 12, therefore, is applicable to research because the first clamping device 21 produces shearing force, produce again simultaneously the situation of torsion, that is to say that torsion can not ignore.In addition, unclamping nut then can make the second clamping device 22 leave the second cushion cap 12, rotate again 22 of the second clamping devices and can change its angle, at last by screwing nut check, make the second clamping device 22 and the second again interlock of cushion cap 12, can apply artificially torsion in this way, conveniently carry out the research of shearing force+torsion.
Because the second clamping device 22 and the second cushion cap 12 are by tooth, groove interlock, therefore, the torsion that applies is controllable, is convenient to carry out quantitative study.
The present invention is not limited to above-mentioned preferred forms, and anyone should learn the structural change of making under enlightenment of the present invention, and every have identical or close technical scheme with the present invention, all falls within protection scope of the present invention.
Claims (8)
1. laboratory animal rabbit lumbar intervertebral disc shear stress loader is characterized in that, comprising:
Support, the top of an one side has a U-shaped breach;
The first clamping device and the second clamping device, be arranged in parallel to each other on the bottom surface of described support, be fixed with a joint pin that vertically arranges on the end face of described the first clamping device, described joint pin runs through described U-shaped breach from bottom to top and passes from the end face of described support, described joint pin has the threaded portion, and be screwed with an adjusting nut on the described threaded portion, described adjusting nut is positioned at described U-shaped breach, the top of described adjusting nut arranges a spring, and described spring housing is contained on the described joint pin and two ends offset with the end face of described adjusting nut and the upper wall of described U-shaped breach respectively.
2. laboratory animal rabbit lumbar intervertebral disc shear stress loader as claimed in claim 1, it is characterized in that, described the first clamping device and described the second clamping device include the first clamping limb and the second clamping limb that the upper end is articulated and connected, the lower end of described the first clamping limb and described the second clamping limb is a hinged claw respectively, two described claws are oppositely arranged, and described the first clamping limb and described the second clamping limb are regulated angle between the two by adjusting device.
3. laboratory animal rabbit lumbar intervertebral disc shear stress loader as claimed in claim 2 is characterized in that described adjusting device comprises:
Adjusting bolt runs through described the first clamping limb and described the second clamping limb;
Nut, spiral shell are contained in the external part of described adjusting bolt.
4. laboratory animal rabbit lumbar intervertebral disc shear stress loader as claimed in claim 3, it is characterized in that, have two the first cushion caps that be arranged in parallel and the second cushion cap on the bottom surface of described support, described the first clamping device is arranged on the bottom surface of described the first cushion cap, and described the second clamping device is arranged on the bottom surface of described the second cushion cap.
5. laboratory animal rabbit lumbar intervertebral disc shear stress loader as claimed in claim 4, it is characterized in that, described the first cushion cap has first through hole that vertically arranges, and described joint pin is installed in described the first through hole and with described first clamping device is threaded fixing after passing described the first cushion cap downwards.
6. laboratory animal rabbit lumbar intervertebral disc shear stress loader as claimed in claim 4, it is characterized in that, described the second cushion cap has second through hole that vertically arranges, and is fixed with a rotating shaft on the end face of described the second clamping device, and described rotating shaft is rotated and is arranged in described the second through hole.
7. laboratory animal rabbit lumbar intervertebral disc shear stress loader as claimed in claim 6 is characterized in that, the upper end of described rotating shaft upwards passes behind described the second cushion cap spacing by jump ring.
8. laboratory animal rabbit lumbar intervertebral disc shear stress loader as claimed in claim 6, it is characterized in that, the upper end of described rotating shaft is fixed by nut after upwards passing described the second cushion cap, along circumferentially being laid with a plurality of tooth bars that distribute radially, the bottom surface of described the second cushion cap is provided with the teeth groove that matches with described tooth bar on the end face of described the second clamping device.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210438551.7A CN102920523B (en) | 2012-11-06 | 2012-11-06 | Experimental animal rabbit lumbar disc shear stress loader |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210438551.7A CN102920523B (en) | 2012-11-06 | 2012-11-06 | Experimental animal rabbit lumbar disc shear stress loader |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102920523A true CN102920523A (en) | 2013-02-13 |
| CN102920523B CN102920523B (en) | 2014-09-10 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201210438551.7A Expired - Fee Related CN102920523B (en) | 2012-11-06 | 2012-11-06 | Experimental animal rabbit lumbar disc shear stress loader |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104885961A (en) * | 2015-05-11 | 2015-09-09 | 同济大学 | Experimental animal caudal vertebra swing device and application thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106073932B (en) * | 2016-05-29 | 2017-12-01 | 中国人民解放军海军总医院 | Lumbar Intervertebral Disc Degeneration animal model biomethanics molding machine |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100249839A1 (en) * | 2009-03-30 | 2010-09-30 | Simpirica Spine, Inc. | Methods and apparatus for improving shear loading capacity of a spinal segment |
| CN102147990A (en) * | 2011-03-08 | 2011-08-10 | 天津理工大学 | Loading device for simulating mechanical environment of vertebral body |
| CN102178567A (en) * | 2011-04-21 | 2011-09-14 | 四川大学华西医院 | Rat spine distracting device |
| CN102743236A (en) * | 2012-07-30 | 2012-10-24 | 中国科学院自动化研究所 | Rabbit spine curving device for experiment |
| CN202920403U (en) * | 2012-11-06 | 2013-05-08 | 王向阳 | Shear stress loader for lumbar disc of experimental animal rabbit |
-
2012
- 2012-11-06 CN CN201210438551.7A patent/CN102920523B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100249839A1 (en) * | 2009-03-30 | 2010-09-30 | Simpirica Spine, Inc. | Methods and apparatus for improving shear loading capacity of a spinal segment |
| CN102147990A (en) * | 2011-03-08 | 2011-08-10 | 天津理工大学 | Loading device for simulating mechanical environment of vertebral body |
| CN102178567A (en) * | 2011-04-21 | 2011-09-14 | 四川大学华西医院 | Rat spine distracting device |
| CN102743236A (en) * | 2012-07-30 | 2012-10-24 | 中国科学院自动化研究所 | Rabbit spine curving device for experiment |
| CN202920403U (en) * | 2012-11-06 | 2013-05-08 | 王向阳 | Shear stress loader for lumbar disc of experimental animal rabbit |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104885961A (en) * | 2015-05-11 | 2015-09-09 | 同济大学 | Experimental animal caudal vertebra swing device and application thereof |
| CN104885961B (en) * | 2015-05-11 | 2017-03-29 | 同济大学 | A kind of laboratory animal caudal vertebra rocking equipment and its application |
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| Publication number | Publication date |
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| CN102920523B (en) | 2014-09-10 |
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Granted publication date: 20140910 Termination date: 20191106 |