CN102138594A - Compound hippophae rhamnoides tea preparation with function of regulating intestinal flora - Google Patents
Compound hippophae rhamnoides tea preparation with function of regulating intestinal flora Download PDFInfo
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- CN102138594A CN102138594A CN 201110034067 CN201110034067A CN102138594A CN 102138594 A CN102138594 A CN 102138594A CN 201110034067 CN201110034067 CN 201110034067 CN 201110034067 A CN201110034067 A CN 201110034067A CN 102138594 A CN102138594 A CN 102138594A
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Abstract
The invention discloses a compound hippophae rhamnoides tea preparation with a function of regulating intestinal flora. The compound hippophae rhamnoides tea preparation comprises the following components in percentage by weight: 15 to 90 percent of fructooligosaccharide, 0 to 40 percent of isomalto oligosaccharide, 0 to 30 percent of oligosaccharide, 1 to 60 percent of hippophae rhamnoides fruit powder, 1 to 60 percent of black tea powder, and 0 to 50 percent of auxiliary materials. The compound hippophae rhamnoides tea preparation integrates modern microecological prebiotic theory, modern nutrition theory and Chinese traditional tea culture, thus a tea beverage which can proliferate intestinal beneficial bacteria and inhibit intestinal pernicious bacteria, and can maintain the flavor and taste of tea is provided.
Description
Technical field
The present invention relates to a kind of compound hippophae rhamnoides tea formulation of regulating the gut flora function that has, belong to field of health care food.
Background technology
Modern microecology viewpoint thinks that the essence of life is the biological balance of ecosystem that forms with internal and external environment, and the essence of disease is that various interference hosts' factor effect is transfinited and caused ecological disturbance.Miscellaneous microorganism that living away from home in healthy people's the intestines and stomach, these microorganisms are called as gut flora.Gut flora makes up according to a certain percentage, conditions each other, depends on each other for existence between each flora, forms a kind of ecological balance on quality and quantity.In case the body internal and external environment changes, as the prolonged application broad-spectrum antibiotic, responsive enteron aisle bacterium is suppressed, not repressed bacterium then seizes the opportunity breeding, thereby causes flora imbalance, and its normal physiological combination is destroyed, produce the pathologic combination and cause clinical symptoms, be called intestinal bacilli illness disease.
The product of the adjusting gut flora function of using includes probio series products, prebiotics series products and symphysis unit series products at present.Wherein, the prebiotics series products has anti-storage, storing advantage such as make things convenient for, has no side effect, and has positive role to regulating gut flora, can effectively suppress harmful bacterium and breed.The present invention is on the basis of existing microecology prebiotics theory; filter out the prebiotics class (FOS, oligoisomaltose, galactooligosaccharide etc.) that effectively to regulate gut flora; be aided with nutritious and have the seabuckthorn fruit powder of protection gastric mucosa effect; the black tea powder that is equipped with the Chinese tea dao culture again carries out the science compatibility, thereby obtains a kind of compound hippophae rhamnoides tea formulation of regulating the gut flora function that has.
Summary of the invention
The object of the present invention is to provide a kind of compound hippophae rhamnoides tea formulation of regulating the gut flora function that has, this compound hippophae rhamnoides tea formulation combines little ecological prebiotics theory of modern times with modern nutriology theory and Chinese conventional tea dao culture, provide a kind of and can either breed intestinal beneficial bacterium and suppress harmful intestinal tract bacteria, can keep the local flavor of tea and the tea-drinking product of taste again.
The objective of the invention is to be achieved through the following technical solutions:
A kind of have a compound hippophae rhamnoides tea formulation of regulating the gut flora function, counts by weight percentage to comprise following component:
FOS 15%～90%, oligoisomaltose 0%～40%,
Galactooligosaccharide 0%～30%, seabuckthorn fruit powder 1%～60%,
Black tea powder 1%～60%, auxiliary material 0%～50%.
Preferably, compound hippophae rhamnoides tea formulation of the present invention, count by weight percentage and comprise following component:
FOS 30%～60%, oligoisomaltose 0%～30%,
Galactooligosaccharide 0%～30%, seabuckthorn fruit powder 1%～30%,
Black tea powder 1%～30%, auxiliary material 0%～35%.
Compound hippophae rhamnoides tea formulation of the present invention can include acceptable auxiliary on the bromatology, thereby makes various peroral dosage forms, as pulvis, granule, tablet, capsule and oral liquid etc.
In the present invention, described auxiliary material is selected from one or more the combination in flavoring essence, sweetener, acid, antioxidant, filler, lubricant and the anticorrisive agent.
Wherein, described flavoring essence comprises lemon extract, ethyl maltol, tea essence and flavoring apple essence etc.; Described sweetener comprises that Sucralose, AK sugar, Aspartame, mogroside and knob are sweet etc.; Described acid comprises citric acid, malic acid and lactic acid etc.; Described antioxidant comprises arabo-ascorbic acid and sodium salt and vitamin C etc.; Described filler comprises fructose, glycitols, sucrose, starch and dextrin etc.; Described lubricant comprises talcum powder, dolomol, silica and stearic acid etc.; Described anticorrisive agent comprises Sodium Benzoate, Potassium Benzoate and potassium sorbate etc.
Compound hippophae rhamnoides tea formulation of the present invention can be made other health food by acceptable composition on bromatology.
In compound hippophae rhamnoides tea formulation of the present invention, described FOS is by the preparation of biological enzymolysis technology and membrane separation technique, and described black tea powder is to adopt the hot water lixiviate and membrane separation technique is extracted from black tea, spray-drying is made with extra care and formed.
FOS is as a kind of natural Oilgosaccharkdes, and its sugariness is about 60% of sucrose, belongs to indigestion sugar, can not increase blood sugar and insulin level in the body after edible, can be excreted by microbial fermentation after entering large intestine.FOS can make the breeding of useful Bifidobacterium increase by 5～10 times, suppresses the growth of harmful bacterium such as bacteroid, clostridium, and it is about 50%～70% that its quantity is reduced, and plays the effect that relaxes bowel, regulates gut flora.Oligoisomaltose and galactooligosaccharide all can not be absorbed by human consumption and directly enter and be utilized by Bifidobacterium in the large intestine, can effectively breed intestinal bifidobacteria and beneficial bacterium.
Sea-buckthorn is risen in the Himalayas and neighboring region thereof, and growth is all arranged in the scope of height above sea level 600-5000 rice, and its fruits nutrition is abundant, the various nutrients that contains needed by human body, be rich in vitamin, can be rated as " king of VC ", also contain flavone compound and other phenolic compound simultaneously.Sea-buckthorn has protection gastric mucosa, protection liver, delays senility, strengthens immunity and function such as anti-oxidant, has the laudatory title of " vitamin treasure-house " and " really long-lived ".
Tea ceremony originates from China the earliest, is regarded as a kind of road of cultivating the moral character and nourishing the nature.And black tea is as the most general a kind of tea-drinking, have the gastro-intestinal digestion of help, promote effects such as appetite, diuresis and elimination oedema, black tea also has stronger antimicrbial power, gargle with black tea and can prevent the flu that filterable virus causes, and can prevent decayed tooth and food poisoning, reduce blood glucose value and hypertension.
Compound hippophae rhamnoides tea formulation of the present invention; be theoretical and modern nutriology theory and Chinese conventional tea dao culture principle of combining according to little ecological prebiotics of modern times; utilize the prebiotics FOS in the microecology; propagation intestinal beneficial bacterium Bifidobacterium; suppress harmful intestinal tract bacteria propagation; keep intestinal environment to be in health status; be aided with nutritious and have the seabuckthorn fruit powder of protection gastric mucosa effect and have the black tea powder of traditional Chinese tea culture; on the basis of local flavor that keeps tea and taste; increase the nutritive value of tea-drinking, realized the combination of tea ceremony culture with health diet.
Compound hippophae rhamnoides tea formulation of the present invention proves through toxicological test, has no side effect, and proves through animal function and human feeding trial, has the health care of regulating gut flora, is suitable for function of intestinal canal disorder person.
Description of drawings
Fig. 1 is preparation technology's flow chart of compound hippophae rhamnoides tea oral liquid of the present invention;
Fig. 2 is preparation technology's flow chart of compound hippophae rhamnoides tea granule of the present invention agent;
Fig. 3 is preparation technology's flow chart of compound hippophae rhamnoides tea hard capsule of the present invention;
Fig. 4 is preparation technology's flow chart of compound hippophae rhamnoides tea tablet of the present invention;
Fig. 5 is preparation technology's flow chart of compound hippophae rhamnoides tea pulvis of the present invention.
The specific embodiment
Embodiment one: the preparation of compound hippophae rhamnoides tea oral liquid of the present invention
Take by weighing each component according to following percentage by weight:
FOS 35.0%, oligoisomaltose 30.0%,
Galactooligosaccharide 10.0%, seabuckthorn fruit powder 15.1%,
Black tea powder 7.00%, malic acid 0.50%,
Citric acid 0.60%, tea essence 1.00%,
AK sugar 0.20%, Sodium Benzoate 0.05%,
Mogroside 0.05%, vitamin C 0.50%.
Above-mentioned each component is mixed, add an amount of purified water and carry out constant volume, behind instantaneous sterilizing, go up the bottle placer can, promptly make compound hippophae rhamnoides tea oral liquid of the present invention after the sterilization.
Embodiment two: the preparation of compound hippophae rhamnoides tea granule of the present invention agent
Take by weighing each component according to following percentage by weight:
FOS 30.0%, oligoisomaltose 15.0%,
Galactooligosaccharide 20.0%, seabuckthorn fruit powder 5.00%,
Black tea powder 8.00%, isomalt 20.0%,
Citric acid 0.75%, tea essence 1.00%,
Aspartame 0.20%, silica 0.05%.
After above-mentioned each component mixed, place granulator to granulate, promptly make compound hippophae rhamnoides tea granule of the present invention agent after the granulation.
Embodiment three: the preparation of compound hippophae rhamnoides tea hard capsule of the present invention
Take by weighing each component according to following percentage by weight:
FOS 60.0%, galactooligosaccharide 30.0%,
Seabuckthorn fruit powder 8.00%, black tea powder 1.80%,
Dolomol 0.10%, silica 0.10%.
After above-mentioned each component mixed, place granulator to granulate, adopt Autocapsulefillingmachine to fill then, after polishing, promptly make compound hippophae rhamnoides tea hard capsule of the present invention.
Embodiment four: the preparation of compound hippophae rhamnoides tea tablet of the present invention
Take by weighing each component according to following percentage by weight:
FOS 35.0%, galactooligosaccharide 25.0%,
Seabuckthorn fruit powder 5.00%, black tea powder 3.00%,
Tea essence 1.50%, mannitol 30.0%,
Dolomol 0.30%, silica 0.20%.
After above-mentioned each component mixed, place granulator to granulate, drying is handled and is placed on tablet press machine and carries out compressing tablet, promptly makes compound hippophae rhamnoides tea tablet of the present invention behind the compressing tablet.
Embodiment five: the preparation of compound hippophae rhamnoides tea pulvis of the present invention
Take by weighing each component according to following percentage by weight:
FOS 50.0%, seabuckthorn fruit powder 30.0%,
Black tea powder 15.2%, ethyl maltol 1.00%,
Citric acid 0.60%, tea essence 1.00%,
Malic acid 0.50%, lemon extract 1.00%,
Mogroside 0.15%, vitamin C 0.50%,
Sucralose 0.05%.
After above-mentioned each component mixed, promptly make compound hippophae rhamnoides tea pulvis of the present invention.
Get the compound hippophae rhamnoides tea pulvis that present embodiment makes, evaluation method according to the Ministry of Public Health's " health food check and assessment technique standard " (version in 2003), prove that through toxicological tests such as acute toxicity test in mice, micronucleus test, spermatic aberration test and Salmonella reversion tests this compound hippophae rhamnoides tea pulvis has no side effect.
According to " evaluation method of health food check and assessment technique standard (version in 2003), carry out animal function and human feeding trial:
1) oral administration gives this product 14 days of mouse 0.83,1.67, three various dose of 5.00g/kg BW, detects the mouse intestinal flora.The result shows: the quantity of Bifidobacterium and lactobacillus increases, and difference has conspicuousness meaning (P＜0.05); There are no significant meaning (P＞0.05) that the number change value difference of enterobacteria, enterococcus and C.perfringens is different; Duration of test, this product does not make significant difference to weight of mice.
2) select standard compliant trial volunteer's 110 examples, by the flora situation before the test, consider factors such as age, sex, diet as far as possible simultaneously, be divided into test group and control group at random, test group is taken this product, every day 2 times, each 1 bag; Control group is taken placebo, takes continuously 15 days.The result shows: take this product after 15 days, test group Bifidobacterium and lactobacillus compare with control group respectively, and group difference has conspicuousness (P＜0.05); Indexs such as C.perfringens, enterobacteria, bacteroid and enterococcus do not have significant change before and after the test, and difference does not have conspicuousness (P＞0.05).
Above animal and human feeding trial presentation of results, this product have the health care of regulating gut flora, are suitable for function of intestinal canal disorder person.
Claims (10)
1. one kind has the compound hippophae rhamnoides tea formulation of regulating the gut flora function, counts by weight percentage to comprise following component:
FOS 15%～90%, oligoisomaltose 0%～40%,
Galactooligosaccharide 0%～30%, seabuckthorn fruit powder 1%～60%,
Black tea powder 1%～60%, auxiliary material 0%～50%.
2. compound hippophae rhamnoides tea formulation according to claim 1 is characterized in that, counts by weight percentage to comprise following component:
FOS 30%～60%, oligoisomaltose 0%～30%,
Galactooligosaccharide 0%～30%, seabuckthorn fruit powder 1%～30%,
Black tea powder 1%～30%, auxiliary material 0%～35%.
3. compound hippophae rhamnoides tea formulation according to claim 1 and 2 is characterized in that: described compound hippophae rhamnoides tea formulation comprises compound hippophae rhamnoides tea pulvis, the agent of compound hippophae rhamnoides tea granule, compound hippophae rhamnoides tea tablet, compound hippophae rhamnoides tea capsule and compound hippophae rhamnoides tea oral liquid.
4. compound hippophae rhamnoides tea formulation according to claim 1 and 2 is characterized in that: described auxiliary material is selected from one or more the combination in flavoring essence, sweetener, acid, antioxidant, filler, lubricant and the anticorrisive agent.
5. compound hippophae rhamnoides tea formulation according to claim 4 is characterized in that: described flavoring essence comprises lemon extract, ethyl maltol, tea essence and flavoring apple essence.
6. compound hippophae rhamnoides tea formulation according to claim 4 is characterized in that: described sweetener comprises that AK sugar, Sucralose, Aspartame, mogroside and knob are sweet; Described acid comprises citric acid, malic acid and lactic acid.
7. compound hippophae rhamnoides tea formulation according to claim 4 is characterized in that: described antioxidant comprises arabo-ascorbic acid and sodium salt and vitamin C.
8. compound hippophae rhamnoides tea formulation according to claim 4 is characterized in that: described filler comprises fructose, glycitols, sucrose, starch and dextrin.
9. compound hippophae rhamnoides tea formulation according to claim 4 is characterized in that: described lubricant comprises talcum powder, dolomol, silica and stearic acid.
10. compound hippophae rhamnoides tea formulation according to claim 4 is characterized in that: described anticorrisive agent comprises Sodium Benzoate, Potassium Benzoate and potassium sorbate.
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Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102771591A (en) * | 2012-08-05 | 2012-11-14 | 林荣贵 | Tea-leaf-free health-care tea sifting tea and preparation method thereof |
| CN103976090A (en) * | 2014-06-04 | 2014-08-13 | 理想科技集团有限公司 | Tea cream capable of relaxing bowels and aiding digestion and preparation method thereof |
| CN104188040A (en) * | 2014-08-18 | 2014-12-10 | 理想科技集团有限公司 | Complex probiotic solid health beverage and preparation method thereof |
| CN105639655A (en) * | 2016-02-26 | 2016-06-08 | 暨南大学 | Health care product capable of promoting proliferation of intestinal bifidobacteria and application |
| CN105875952A (en) * | 2016-04-15 | 2016-08-24 | 江苏微康生物科技有限公司 | Probiotic black tea and preparation method thereof |
| CN105994732A (en) * | 2016-01-04 | 2016-10-12 | 赵蔚风 | Sea-buckthorn black tea |
| CN106615475A (en) * | 2017-01-16 | 2017-05-10 | 柳培健 | Health type seabuckthorn tea and preparation method thereof |
| CN106617091A (en) * | 2016-11-08 | 2017-05-10 | 广东正当年生物科技有限公司 | Probiotics and prebiotic compound preparation |
| CN107149619A (en) * | 2017-05-18 | 2017-09-12 | 四川悦艾健康科技有限公司 | Harmful bacteria breeding can be suppressed and the compound preparation of growth of probiotics can be promoted |
| CN108157978A (en) * | 2017-12-30 | 2018-06-15 | 上海健煌生物科技有限公司 | A kind of peptide composition of adjusting intestinal flora containing burdock polysaccharide and application |
| CN108402417A (en) * | 2018-02-09 | 2018-08-17 | 山西省林业科学研究院 | A kind of preparation method of sea-buckthorn benefit intestines lozenge |
| CN108576322A (en) * | 2018-05-16 | 2018-09-28 | 延安圆方（集团）公司 | A kind of production method of sea-buckthorn black tea and application |
| CN111096989A (en) * | 2018-10-25 | 2020-05-05 | 陕西康达福医药科技有限公司 | Composition for treating functional constipation and preparation method and application thereof |
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| CN101233947A (en) * | 2008-03-06 | 2008-08-06 | 王跃进 | Sports strengthening plant effervescence tablet beverage |
| CN101238882A (en) * | 2007-09-21 | 2008-08-13 | 卢存国 | Lead excluding health care food |
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2011
- 2011-02-01 CN CN 201110034067 patent/CN102138594B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101238882A (en) * | 2007-09-21 | 2008-08-13 | 卢存国 | Lead excluding health care food |
| CN101233947A (en) * | 2008-03-06 | 2008-08-06 | 王跃进 | Sports strengthening plant effervescence tablet beverage |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102771591A (en) * | 2012-08-05 | 2012-11-14 | 林荣贵 | Tea-leaf-free health-care tea sifting tea and preparation method thereof |
| CN103976090A (en) * | 2014-06-04 | 2014-08-13 | 理想科技集团有限公司 | Tea cream capable of relaxing bowels and aiding digestion and preparation method thereof |
| CN104188040A (en) * | 2014-08-18 | 2014-12-10 | 理想科技集团有限公司 | Complex probiotic solid health beverage and preparation method thereof |
| CN105994732A (en) * | 2016-01-04 | 2016-10-12 | 赵蔚风 | Sea-buckthorn black tea |
| CN105639655A (en) * | 2016-02-26 | 2016-06-08 | 暨南大学 | Health care product capable of promoting proliferation of intestinal bifidobacteria and application |
| CN105875952A (en) * | 2016-04-15 | 2016-08-24 | 江苏微康生物科技有限公司 | Probiotic black tea and preparation method thereof |
| CN106617091A (en) * | 2016-11-08 | 2017-05-10 | 广东正当年生物科技有限公司 | Probiotics and prebiotic compound preparation |
| CN106615475A (en) * | 2017-01-16 | 2017-05-10 | 柳培健 | Health type seabuckthorn tea and preparation method thereof |
| CN107149619A (en) * | 2017-05-18 | 2017-09-12 | 四川悦艾健康科技有限公司 | Harmful bacteria breeding can be suppressed and the compound preparation of growth of probiotics can be promoted |
| CN108157978A (en) * | 2017-12-30 | 2018-06-15 | 上海健煌生物科技有限公司 | A kind of peptide composition of adjusting intestinal flora containing burdock polysaccharide and application |
| CN108402417A (en) * | 2018-02-09 | 2018-08-17 | 山西省林业科学研究院 | A kind of preparation method of sea-buckthorn benefit intestines lozenge |
| CN108576322A (en) * | 2018-05-16 | 2018-09-28 | 延安圆方（集团）公司 | A kind of production method of sea-buckthorn black tea and application |
| CN111096989A (en) * | 2018-10-25 | 2020-05-05 | 陕西康达福医药科技有限公司 | Composition for treating functional constipation and preparation method and application thereof |
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Effective date of registration: 20170126 Address after: 528402 Dongming Road, Guangdong city of Zhongshan province (Shiqi District Private Science and Technology Park) Patentee after: Perfect (China) Co., Ltd. Patentee after: Perfect (Guangdong) Commodity Co., Ltd. Address before: 528402 Dongming Road, Guangdong city of Zhongshan province (Shiqi District Private Science and Technology Park) Patentee before: Perfect (China) Co., Ltd. |