CN102138558B - Antibacterial composition containing fenbuconazole and antibiotic compounds - Google Patents
Antibacterial composition containing fenbuconazole and antibiotic compounds Download PDFInfo
- Publication number
- CN102138558B CN102138558B CN201110040076.3A CN201110040076A CN102138558B CN 102138558 B CN102138558 B CN 102138558B CN 201110040076 A CN201110040076 A CN 201110040076A CN 102138558 B CN102138558 B CN 102138558B
- Authority
- CN
- China
- Prior art keywords
- active component
- jinggangmeisu
- kasugarnycin
- zhongshengmycin
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses an antibacterial composition containing fenbuconazole and antibiotic compounds, which comprises an active component A and an active component B, wherein the active component A is fenbuconazole; the active component B may be any one of the following bactericides: Jinggang mycin, Zhongsheng mycin and Chunlei mycin; and the weight ratio of the active component A to the active component B is (1-50):(1-50). The composition disclosed by the invention can prevent and control various diseases in crops, has obvious synergetic effect and a broader antibacterial spectrum and has high activities for banded sclerotial blight, rice blast, ring spot, powdery mildew, downy mildew, botrytis, leaf mold, droop, pestilence, and alternaria leaf spot; and when the composition is use, the pesticide dose is reduced, the pesticide residue on the crops is reduced, and environmental pollution is relieved.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of bactericidal composition that contains RH-7592 and antibiotic compound.
Background technology
RH-7592, English name: fenbuconazole, molecular formula: C
19h
17clN
4, chemical name: 4-(4-chlorphenyl)-2-phenyl-2 (1H-1,2,4-triazol-1-yl methyl) butyronitrile, structural formula:
RH-7592 sterol demethylation inhibitor, inner sucting conduction type bactericide, can suppress the elongation of pathogen mycelia, stops the germ spore having germinateed to be invaded and makes fabric texture.Use latent period germ, can stop the growth of germ, after morbidity, use, can make spore distortion of future generation, lose continuation contagion probability, to disease, existing thick anti-effect has again therapeutic action.
But in the real process of agricultural production, preventing and treating the problem that disease the most easily produces is the drug-fast generation of germ.Different cultivars composition carries out composite, is to prevent and treat the very common method of resistance germ.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals is all additive effect, really have a synergistic effect composite seldom, especially synergistic effect very obviously, synergy ratio very high composite just still less.Through inventor research, find after RH-7592 and jinggangmeisu, Zhongshengmycin, kasugarnycin is composite to produce good synergistic effect, and not yet open about the composite relevant report of RH-7592 and jinggangmeisu, Zhongshengmycin, kasugarnycin.
Summary of the invention
A kind of bactericidal composition that contains RH-7592 and antibiotic compound, comprise effective active component, auxiliary agent and filler, it is characterized in that: active component A, B percentage by weight are 1～50%: 1～50%, active components A is selected from RH-7592, and active component B is the one in jinggangmeisu, Zhongshengmycin, kasugarnycin.
Described a kind of bactericidal composition that contains RH-7592 and antibiotic compound, is characterized in that: the percentage by weight of A, two kinds of active components of B is 1～40%: 1～40%.
The described bactericidal composition that contains RH-7592, is characterized in that: the percentage by weight of RH-7592 and jinggangmeisu is 5～20%: 5～30%.
The described bactericidal composition that contains RH-7592, is characterized in that: the percentage by weight of RH-7592 and Zhongshengmycin is 5～30%: 5～20%.
The described bactericidal composition that contains RH-7592, is characterized in that: the percentage by weight of RH-7592 and kasugarnycin is 5～30%: 5～30%.
The percentage by weight of A, two kinds of active components of B is 1～50%: 1～50%.Conventionally in composition, active weight percentage is gross weight 0.5～90%, is preferably 5%～85%.According to different preparation types, active component content scope is different.Conventionally, liquid preparation contains 1～70% active substance by weight, is preferably 5～50%; Solid pharmaceutical preparation contains 5～85% active substance by weight, is preferably 10～80%.
In bactericidal composition of the present invention, at least contain a kind of surfactant, the dispersion of active component in water while being beneficial to use.Surface-active contents is 5～30% of total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from one or more in dispersant, wetting agent, binding agent or defoamer.According to different dosage form, in preparation, can also contain disintegrant known in those skilled in the art, antifreeze etc.
Described dispersant is selected from alkylnaphthalene sulfonate, two (alkyl) naphthalenesulfonate formaldehyde condensation compound, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy is phonetic, aliphatic amine polyoxyethylene is phonetic, polyoxyethylene carboxylate, one or more during ester polyoxyethylene is phonetic.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, silkworm excrement, soapberry powder.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, aluminium chloride.
Described binding agent is selected from: one or more in gum Arabic, xanthans, sodium phosphate trimer, phenolic resins, sodium alginate, white dextrin, methylcellulose, PAA, polyvinylpyrrolidone, crospolyvinylpyrrolidone, polyethylene glycol, polyvinyl alcohol.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, polyethylene glycol.
Described defoamer is selected from: silicone, C
8～10aliphatic alcohols, C
10～20one or more in saturated fat acids (as capric acid) and acid amides, silicone oil, silicone compound.
Described emulsifier is selected from: agriculture breast 500# (alkyl benzene calcium sulfonate), OP series phosphate (polyoxyethylene nonylphenol ether phosphate), 600# phosphate (phenyl phenol polyoxy ethyl ether phosphate), styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, agriculture breast 400# (benzyl dimethyl phenol polyoxy ethyl ether), agriculture breast 600# (phenyl phenol polyoxy ethyl ether), Nongru-700 # (alkylphenol-formaldehyde resin polyoxy ethyl ether), agriculture breast 36# (phenethyl fluosite polyoxy ethyl ether), agriculture breast 1600# (phenethyl phenol polyoxy ethyl polypropylene-base ether), ethylene oxide-propylene oxide block copolymer, OP series (polyoxyethylene nonylphenol ether), By series (castor oil polyoxyethylene ether), agriculture breast 33# (alkylaryl polyoxyethylene polyoxypropylene ether), agriculture breast 34# (alkylaryl polyoxyethylene poly-oxygen propylene aether), sapn series (sorbitan monostearate), tween series (sorbitan fatty acid ester APEO), one or more in AEO series (fat alcohol alcohol APEO).
Described stabilizing agent is selected from one or more in sodium sorbate, butyl glycidyl ether, phenyl glycidyl ether, cresyl glycidyl ether, polyethylene glycol diglycidyl ether;
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, precipitated calcium carbonate.
Composition of the present invention can be by user before use through dilution or directly use.Its preparation can be prepared by common processing method, after mixing, then adds surfactant as one or more in dispersant, stabilizing agent, wetting agent, adhesive, defoamer etc. by active substance with liquid flux or solid carrier.
Bactericidal composition of the present invention, can be processed into acceptable formulation on any agricultural chemicals on demand.Wherein preferred dosage form is wetting powder, water dispersible granules, suspending agent, suspension emulsion.
When making wetting powder, composition comprises following constituent content: RH-7592 1～50%, active component B1～50%, dispersant 5～10%, wetting agent 2～10%, filler 8～91%.
Active component RH-7592, active component B, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, can be made into the wetting powder product of the present composition.
When making water dispersible granules, composition comprises following constituent content: active component RH-7592 1～50%, active component B1～50%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, binding agent 1～8%, filler 10～92%.
Active component RH-7592, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained to the particle diameter needing through air-flow crushing together, then add other auxiliary agents such as binding agent, obtain the materials of granulating.By item quantitatively send in fluidized bed granulation dryer through granulation and dry after, make the water dispersible granules product of the present composition.
When making suspending agent, composition comprises following constituent content: active component RH-7592 1～30%, active component B1～30%, dispersant 2～10%, wetting agent 2～10%, defoamer 0.1～1%, binding agent 0.1～2%, antifreeze 0.1～8%, deionized water add to 100%.
Dispersant, wetting agent, defoamer, thickener, antifreeze in above-mentioned formulation material are mixed through high speed shear, add active component RH-7592, active component B, ball milling 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make the suspending agent product of the present composition.
When making suspension emulsion, composition comprises following constituent content: RH-7592 1～30%, active component B1～30%, emulsifier 2～12%, dispersant 2～10%, defoamer 0.1～2%, thickener 0.1～2%, antifreeze 0.1～8%, stabilizing agent 0.05～3%, water add to 100%.
Dispersant, defoamer, thickener, antifreeze, stabilizing agent in above-mentioned formulation material are mixed through high speed shear, add the former medicine of effective active composition B, ball milling 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make effective active composition B suspending agent, then by former RH-7592 medicine, emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, make the suspension emulsion product of the present composition.
The invention has the advantages that: after (1) RH-7592 and active component B are composite, have and obviously continue synergistic effect; (2) expanded fungicidal spectrum, banded sclerotial blight, rice blast, ring spot, powdery mildew, downy mildew, gray mold, leaf mold, fusarium wilt, epidemic disease, spot defoliation disease have all been had to greater activity; (3) the present invention not with an organic solvent, is difficult for producing poisoning, is convenient to transport and storage; (4) reduce the dosage of agricultural chemicals, reduced the residual quantity of agricultural chemicals on crop, alleviated environmental pollution.
Embodiment
Below in conjunction with embodiment, to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.
The embodiment of the present invention is the method that adopts Toxicity Determination and field trial to combine.
Application Example one
Example 1 50% RH-7592 jinggangmeisu wetting powder
RH-7592 15%, jinggangmeisu 35%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 6%, neopelex 5%, kaolin add to 100%, and mixture carries out air-flow crushing, make 50% RH-7592 jinggangmeisu wetting powder.
Example 2 60% RH-7592 jinggangmeisu wetting powders
RH-7592 20%, jinggangmeisu 40%, lignosulfonates 8%, Nekal BX 6%, bentonite add to 100%, and mixture carries out air-flow crushing, make 60% RH-7592 jinggangmeisu wetting powder.
Example 3 50% RH-7592 jinggangmeisu water dispersible granules
RH-7592 10%, jinggangmeisu 40%, silkworm excrement 4%, the phonetic formaldehyde condensation products sulphate 6% of alkylphenol-polyethenoxy, sodium bicarbonate 1.2%, starch add to 100%, mix and make 50% RH-7592 jinggangmeisu water dispersible granules.
Example 4 50% RH-7592 jinggangmeisu water dispersible granules
RH-7592 20%, jinggangmeisu 30%, spaonin powder 5%, alkyl benzene sulfonate calcium salt 6%, bentonite add to 100%, mix and make 50% RH-7592 jinggangmeisu water dispersible granules.
Example 5 30% RH-7592 jinggangmeisu suspending agents
RH-7592 10%, jinggangmeisu 20%, polyoxyethylene carboxylate 6%, soapberry powder 7%, silicone oil 0.2%, xanthans 1.2%, diethylene glycol (DEG) 1.5%, deionized water add to 100%, mix and make 30% RH-7592 jinggangmeisu suspending agent.
Example 6 50% RH-7592 jinggangmeisu suspending agents
RH-7592 5%, jinggangmeisu 45%, aryl phenol polyoxyethylene succinate sulfonate 6%, lauryl sodium sulfate 5%, silicone compound 0.4%, polyvinylpyrrolidone 1.3%, polyethylene glycol 1.4%, deionized water add to 100%, mix and make 50% RH-7592 jinggangmeisu suspending agent.
Example 7 25% RH-7592 jinggangmeisu suspension emulsions
RH-7592 5%, jinggangmeisu 20%, aliphatic amine polyoxyethylene are phonetic 8%, wetting and penetrating agent F 6%, C
8～10aliphatic alcohols 0.5%, gum Arabic 1.3%, 600# phosphate 6%, glycerine 1.1%, water add to 100%, and aforementioned formula material is mixed, and make 25% RH-7592 jinggangmeisu suspension emulsion.
Example 8 30% RH-7592 jinggangmeisu suspension emulsions
RH-7592 24%, jinggangmeisu 6%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 5%, lauryl sodium sulfate 4%, agriculture breast 1600#8%, sodium phosphate trimer 1.4%, triethylene glycol 1.2%, C
10～20saturated fat acids 0.3%, water add to 100%, make 30% RH-7592 jinggangmeisu suspension emulsion through mixing.
Example 9 40% RH-7592 Zhongshengmycin wetting powders
RH-7592 32%, Zhongshengmycin 8%, lignosulfonates 6%, soapberry powder 5%, kaolin add to 100%, and mixture carries out air-flow crushing, make 40% RH-7592 Zhongshengmycin wetting powder.
Example 10 54% RH-7592 Zhongshengmycin wetting powders
RH-7592 48%, Zhongshengmycin 6%, alkyl benzene sulfonate calcium salt 7%, spaonin powder 5%, precipitated calcium carbonate add to 100%, and mixture carries out air-flow crushing, make 54% RH-7592 Zhongshengmycin wetting powder.
Example 11 40% RH-7592 Zhongshengmycin water dispersible granules
RH-7592 30%, Zhongshengmycin 10%, two (alkyl) naphthalenesulfonate formaldehyde condensation compound 6%, silkworm excrement 5%, ammonium sulfate 1%, starch add to 100%, mix and make 40% RH-7592 Zhongshengmycin water dispersible granules.
Example 12 60% RH-7592 Zhongshengmycin water dispersible granules
RH-7592 40%, Zhongshengmycin 20%, alkylphenol-polyethenoxy are phonetic 8%, lauryl sodium sulfate 7%, bentonite add to 100%, mix and make 60% RH-7592 Zhongshengmycin water dispersible granules.
Example 13 30% RH-7592 Zhongshengmycin suspending agents
RH-7592 20%, Zhongshengmycin 10%, aryl phenol polyoxyethylene succinate sulfonate 7%, neopelex 6%, C
10～20saturated fat acids 0.4%, sodium alginate 1.2%, ethylene glycol 1.1%, deionized water add to 100%, mix and make 30% RH-7592 Zhongshengmycin suspending agent.
Example 14 45% RH-7592 Zhongshengmycin suspending agents
RH-7592 30%, Zhongshengmycin 15%, lignosulfonates 5%, wetting and penetrating agent F 4%, silicone oil 0.2%, xanthans 1.4%, diethylene glycol (DEG) 1.6%, deionized water add to 100%, mix and make 45% RH-7592 Zhongshengmycin suspending agent.
Example 15 15% RH-7592 Zhongshengmycin suspension emulsions
RH-7592 5%, Zhongshengmycin 10%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 8%, Nekal BX 7%, C
8～10aliphatic alcohols 0.3%, methylcellulose 1.2%, glycerine 1.4%, agriculture breast 34#8%, water add to 100%, and aforementioned formula material is mixed, and make 15% RH-7592 Zhongshengmycin suspension emulsion.
Example 16 35% RH-7592 Zhongshengmycin suspension emulsions
RH-7592 25%, Zhongshengmycin 10%, aliphatic amine polyoxyethylene are phonetic 6%, neopelex 5%, sodium phosphate trimer 0.8%, polyethylene glycol 1.2%, silicone compound 0.4%, tween series 6%, water add to 100%, make 35% RH-7592 Zhongshengmycin suspension emulsion through mixing.
Example 17 40% RH-7592 kasugarnycin wetting powders
RH-7592 30%, kasugarnycin 10%, polycarboxylate 7%, spaonin powder 5%, diatomite add to 100%, and mixture carries out air-flow crushing, make 40% RH-7592 kasugarnycin wetting powder.
Example 18 60% RH-7592 kasugarnycin wetting powders
RH-7592 30%, kasugarnycin 30%, polyoxyethylene carboxylate 8%, silkworm excrement 6%, kaolin add to 100%, and mixture carries out air-flow crushing, make 60% RH-7592 kasugarnycin wetting powder.
Example 19 50% RH-7592 kasugamycin water-dispersion granules
RH-7592 40%, kasugarnycin 10%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 5%, soapberry powder 5%, aluminium chloride 1%, bentonite add to 100%, mix and make 50% RH-7592 kasugamycin water-dispersion granule.
Example 20 60% RH-7592 kasugamycin water-dispersion granules
RH-7592 15%, kasugarnycin 45%, lignosulfonates 6%, Nekal BX 5%, sodium bicarbonate 1.2%, kaolin add to 100%, mix and make 60% RH-7592 kasugamycin water-dispersion granule.
Example 21 10% RH-7592 kasugarnycin suspending agents
RH-7592 5%, kasugarnycin 5%, ester polyoxyethylene are phonetic 7%, wetting and penetrating agent F 5%, silicone oil 0.3%, PAA 1.1%, ethylene glycol 1.3%, deionized water add to 100%, mix and make 10% RH-7592 kasugarnycin suspending agent.
Example 22 30% RH-7592 kasugarnycin suspending agents
RH-7592 27%, kasugarnycin 3%, the phonetic formaldehyde condensation products sulphate 8% of alkylphenol-polyethenoxy, lauryl sodium sulfate 7%, C
8～10aliphatic alcohols 0.4%, methylcellulose 1.2%, glycerine 1.5%, deionized water add to 100%, mix and make 30% RH-7592 kasugarnycin suspending agent.
Example 23 30% RH-7592 kasugarnycin suspension emulsions
RH-7592 10%, kasugarnycin 20%, polyoxyethylene carboxylate 7%, neopelex 5%, C
10～20saturated fat acids 0.2%, triethylene glycol 1.6%, sodium phosphate trimer 1.3%, agriculture breast 500#7%, water adds to 100%, mixes and makes 30% RH-7592 kasugarnycin suspension emulsion.
Example 24 35% RH-7592 kasugarnycin suspension emulsions
RH-7592 25%, kasugarnycin 10%, aryl phenol polyoxyethylene succinate sulfonate 6%, lauryl sodium sulfate 5%, methylcellulose 1.5%, sapn series 8%, silicone compound 0.3%, polyethylene glycol 1.2%, water add to 100%, mix and make 35% RH-7592 kasugarnycin suspension emulsion.
The embodiment of the present invention is the method that adopts Toxicity Determination and field trial to combine.The embodiment of the present invention is the method that adopts Toxicity Determination and field trial to combine.First pass through Toxicity Determination, synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR < 0.5 is antagonism, 0.5≤SR≤1.5 are summation action, SR > 1.5 is synergistic effect, on this basis, then carry out field trial.
RH-7592 and active component B (B is selected from the one of jinggangmeisu, Zhongshengmycin, kasugarnycin) are composite to crop pest Toxicity Determination.
After the effective inhibition concentration scope of each medicament is determined in prerun, each medicament is established respectively 5 dosage processing by active constituent content, establishes clear water contrast.Carry out with reference to " farm-chemical indoor determination test rule bactericide ", adopt mycelial growth rate method to measure the virulence of medicament to crop germ.After 72h, measure colony diameter by right-angled intersection method, calculate each processing net growth, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), liquor strength (μ g/mL) converts logarithm value (x) to, try to achieve virulence regression equation (y=a+bx) with method of least squares, and calculate thus the EC of every kind of medicament
50value.Calculate the different proportioning synergy ratios of two medicaments (SR) according to Wadley method, SR < 0.5 is antagonism simultaneously, and 0.5≤SR≤1.5 are summation action, and SR > 1.5 is synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active component RH-7592 and active component B (jinggangmeisu, Zhongshengmycin, kasugarnycin) shared ratio in combination;
A is RH-7592;
B is the one in jinggangmeisu, Zhongshengmycin, kasugarnycin.
Implementation of an application example two
RH-7592 and composite jinggangmycin are to rice sheath blight disease Toxicity Determination.
Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining RH-7592, the former medicine of jinggangmeisu and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 1 RH-7592, jinggangmeisu and the composite toxicity test analysis of results table to rice sheath blight disease thereof
As shown in Table 1, RH-7592, the EC of jinggangmeisu to rice sheath blight disease
50be respectively 1.03mg/L and 2.08mg/L.RH-7592 and jinggangmeisu proportioning were at 50: 1 to 1: 50 o'clock, synergy ratio SR is all greater than 1.5, illustrate that RH-7592 and jinggangmeisu mixture in 50: 1 to 1: 50 scopes all shows synergistic effect, especially when the two proportioning is during at 4: 1 to 1: 8, synergistic effect is more obviously outstanding, wherein synergy ratio SR maximum in the time that RH-7592 and jinggangmeisu weight ratio are 1: 2, synergistic effect is the most obvious.
Implementation of an application example three
RH-7592 and Zhongshengmycin are composite to ring rot of apple Toxicity Determination.
Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining RH-7592, the former medicine of Zhongshengmycin and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 2 RH-7592, Zhongshengmycin and the composite toxicity test analysis of results table to ring rot of apple thereof
As shown in Table 2, RH-7592, the EC of Zhongshengmycin to ring rot of apple
50be respectively 1.32mg/L and 0.75mg/L.RH-7592 and Zhongshengmycin proportioning were at 50: 1 to 1: 50 o'clock, synergy ratio SR is all greater than 1.5, illustrate that RH-7592 and Zhongshengmycin mixture in 50: 1 to 1: 50 scopes all shows synergistic effect, especially when the two proportioning is during at 8: 1 to 1: 4, synergistic effect is more obviously outstanding, wherein synergy ratio SR maximum in the time that RH-7592 and Zhongshengmycin weight ratio are 2: 1, synergistic effect is the most obvious.
Implementation of an application example four:
RH-7592 and kasugarnycin are composite to cladosporium leaf and fruit mould of tomato Toxicity Determination.
Test medicine provides by Shaanxi Meibang Pesticide Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining RH-7592, the former medicine of kasugarnycin and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 3 RH-7592, kasugarnycin and the composite toxicity test analysis of results table to cladosporium leaf and fruit mould of tomato thereof
As shown in Table 3, RH-7592, the EC of kasugarnycin to cladosporium leaf and fruit mould of tomato
50be respectively 0.94mg/L and 0.81mg/L.RH-7592 compares at 50: 1 to 1: 50 o'clock with kasugarnycin, synergy ratio SR is all greater than 1.5, illustrate that RH-7592 and kasugarnycin mixture in 50: 1 to 1: 50 scopes all shows synergistic effect, especially when the two proportioning is during at 9: 1 to 1: 9, synergistic effect is more obviously outstanding, wherein synergy ratio SR maximum in the time that RH-7592 and kasugarnycin weight ratio are 1: 1, synergistic effect is the most obvious.
Application Example five RH-7592 and jinggangmeisu and the composite rice sheath blight disease test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is in Nanning suburban district, Guangxi province, and test medicine is researched and developed, provided by Shaanxi Meibang Pesticide Co., Ltd., contrast medicament 24% RH-7592 missible oil (commercial), 5% jinggangmeisu aqua (commercial).
Investigation rice sheath blight disease disease index before medicine, in their early stage dispenser, dispenser for the second time after 10 days, dispenser 2 times altogether, investigates disease indexs and calculates preventive effect for after dispenser 7 days, 14 days for the second time.Experimental result is as follows:
Table 4 RH-7592, jinggangmeisu and the composite rice sheath blight disease test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 4, after RH-7592 and composite jinggangmycin, can effectively prevent and treat rice sheath blight disease, control efficiency is all better than the preventive effect of single dose.In test scope of medication, target crop is had no adverse effects, and rice blast is had to certain preventive effect.
Application Example six RH-7592 and Zhongshengmycin and the composite ring rot of apple test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is in Xi Zhangbao township, Liquan County, Shaanxi Province, and test medicine is researched and developed, provided by Shaanxi Meibang Pesticide Co., Ltd., contrast medicament 24% RH-7592 missible oil (commercial), 3% Zhongshengmycin wetting powder (commercial).
The investigation ring rot of apple state of an illness before medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in every 7 days once, is total to dispenser 2 times.Within after dispenser 7 days, 14 days for the second time, investigate respectively disease index and calculate preventive effect.Experimental result is as follows:
Table 5 RH-7592, Zhongshengmycin and the composite ring rot of apple test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 5, after RH-7592 and Zhongshengmycin are composite, can effectively prevent and treat ring rot of apple, control efficiency is all better than the preventive effect of single dose.In test scope of medication, target crop is had no adverse effects.
Application Example seven RH-7592 and kasugarnycin and the composite cladosporium leaf and fruit mould of tomato test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is in Changan District, Shaanxi Province, and test medicine is researched and developed, provided by Shaanxi Meibang Pesticide Co., Ltd., contrast medicament 24% RH-7592 missible oil (commercial), 2% kasugarnycin aqua (commercial).
Investigation cladosporium leaf and fruit mould of tomato disease index before medicine, in their early stage dispenser, dispenser for the second time after 10 days, dispenser 2 times altogether, investigates disease indexs and calculates preventive effect for after dispenser 7 days, 14 days for the second time.Experimental result is as follows:
Table 6 RH-7592, kasugarnycin and the composite cladosporium leaf and fruit mould of tomato test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 6, after RH-7592 and kasugarnycin are composite, can effectively prevent and treat cladosporium leaf and fruit mould of tomato, control efficiency is all better than the preventive effect of single dose.In test scope of medication, target crop is had no adverse effects.
Claims (6)
1. a bactericidal composition that contains RH-7592 and antibiotic compound, by effective active composition, auxiliary agent and media assemblage, it is characterized in that: active component A, B weight ratio are 50:1 ~ 1:50, described active component A is RH-7592, and active component B is selected from the one in jinggangmeisu, kasugarnycin.
2. a kind of bactericidal composition that contains RH-7592 and antibiotic compound according to claim 1, is characterized in that: the weight ratio of A, two kinds of active components of B is 40:1 ~ 1:40.
3. the bactericidal composition that contains RH-7592 and antibiotic compound according to claim 2, is characterized in that: the weight ratio of RH-7592 and jinggangmeisu is 4:1 ~ 1:8.
4. the bactericidal composition that contains RH-7592 and antibiotic compound according to claim 2, is characterized in that: the weight ratio of RH-7592 and kasugarnycin is 9:1 ~ 1:9.
5. the bactericidal composition that contains RH-7592 and antibiotic compound according to claim 1, is characterized in that: composition is made wetting powder, water dispersible granules, suspending agent, suspension emulsion.
6. the bactericidal composition that contains RH-7592 and antibiotic compound according to claim 1 is for preventing and treating the purposes of disease on paddy rice, vegetables, fruit tree.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110040076.3A CN102138558B (en) | 2011-02-17 | 2011-02-17 | Antibacterial composition containing fenbuconazole and antibiotic compounds |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110040076.3A CN102138558B (en) | 2011-02-17 | 2011-02-17 | Antibacterial composition containing fenbuconazole and antibiotic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102138558A CN102138558A (en) | 2011-08-03 |
| CN102138558B true CN102138558B (en) | 2014-08-13 |
Family
ID=44406538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201110040076.3A Active CN102138558B (en) | 2011-02-17 | 2011-02-17 | Antibacterial composition containing fenbuconazole and antibiotic compounds |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102138558B (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101554168A (en) * | 2009-04-08 | 2009-10-14 | 湖南万家丰科技有限公司 | Sterilization composition containing Tebuconazole and Validamycin |
| CN101940209B (en) * | 2010-06-01 | 2013-04-03 | 江苏七洲绿色化工股份有限公司 | Sterilizing composition containing cyproconazole and validamycin A and preparation method thereof |
-
2011
- 2011-02-17 CN CN201110040076.3A patent/CN102138558B/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN102138558A (en) | 2011-08-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102224822B (en) | Microbicidal composition containing chloroisobromine cyanuric acid and antibiotics | |
| CN102017955B (en) | Bactericidal composite containing metconazole and methoxy acrylate compounds | |
| CN102057914B (en) | Bactericidal composition containing metconazole and antibiotic compound | |
| CN102334493B (en) | Novel fluopicolide-containing antibacterial composition | |
| CN102204536A (en) | Antibacterial composition containing picoxystrobin and antibiotic compound | |
| CN102057908B (en) | Bactericidal composite containing dithianon and methoxy acrylic esters | |
| CN103238608A (en) | Sterilization composition containing fluoxastrobin and antibiotics | |
| CN102057913B (en) | Bactericidal composition containing triflumizole and triazole compound | |
| CN102037974B (en) | Sterilization composition containing triticonazole and methoxyl acrylate | |
| CN102138558B (en) | Antibacterial composition containing fenbuconazole and antibiotic compounds | |
| CN102057909B (en) | Bactericidal composition containing triflumizole and antibiotic compounds | |
| CN102197820A (en) | Bactericidal composition containing picoxystrobin and benzimidazoles | |
| CN102204552A (en) | Antibacterial composition containing enestroburin and antibiotic compound | |
| CN102057927A (en) | Bactericidal composition containing captan and triazole compounds | |
| CN102150683B (en) | Fenbuconazole-containing synergic sterilization composition | |
| CN102057916A (en) | Bactericidal composition containing fenbuconazole and strobilurin compound | |
| CN102090407B (en) | Bactericidal composition containing bitertanol and antibiotic type compound | |
| CN102204544A (en) | Picoxystrobin-containing synergic bactericidal composition | |
| CN102165957B (en) | Synergic sterilizing composite containing fenbuconazole and triazole compound | |
| CN102217618B (en) | Bactericidal composition containing trifloxystrobin and antibiotic compounds | |
| CN102067861A (en) | Fenbuconazole-containing bactericidal composition | |
| CN102057935B (en) | Bactericidal composition containing imidazole | |
| CN103392719B (en) | Bactericidal composition containing iminazoles and methoxy acrylates | |
| CN102037969B (en) | Sterilization composition containing imibenconazole and methoxyl acrylate compound | |
| CN102067862A (en) | Ipconazole-containing bactericidal composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C53 | Correction of patent for invention or patent application | ||
| CB02 | Change of applicant information |
Address after: 715500 Weinan City, Shaanxi province Pucheng County agricultural base industrial park Applicant after: Shaanxi Meibang Pesticide Co., Ltd. Address before: 710075, C, 15 floor, Jinqiao International Plaza, science and technology road, hi tech Zone, Shaanxi, Xi'an Applicant before: Shaanxi Meibang Pesticide Co., Ltd. |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: Nie Jianjun Inventor before: Zhang Wei Inventor before: Cao Qiaoli Inventor before: Gao Chao |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20171221 Address after: 221000 middle section of Pei Jing Road, Zhang Zhai Town, Xuzhou, Jiangsu, Peixian Patentee after: Wansheng Xuzhou Modern Agriculture Development Co., Ltd. Address before: 715500 Weinan City, Shaanxi province Pucheng County agricultural base industrial park Patentee before: Shaanxi Meibang Pesticide Co., Ltd. |