CN102132870B - Diet health-care product and preparation method thereof - Google Patents

Diet health-care product and preparation method thereof Download PDF

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Publication number
CN102132870B
CN102132870B CN201110046299A CN201110046299A CN102132870B CN 102132870 B CN102132870 B CN 102132870B CN 201110046299 A CN201110046299 A CN 201110046299A CN 201110046299 A CN201110046299 A CN 201110046299A CN 102132870 B CN102132870 B CN 102132870B
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parts
health product
weight portion
preparation
slimming health
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CN102132870A (en
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左文健
戴好富
梅文莉
王辉
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Institute of Tropical Bioscience and Biotechnology Chinese Academy of Tropical Agricultural Sciences
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Institute of Tropical Bioscience and Biotechnology Chinese Academy of Tropical Agricultural Sciences
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Abstract

The invention discloses a diet health-care product, which is prepared from the following raw materials in part by weight: 1 to 4 parts of folium llicis latifoliae, 2 to 5 parts of hawthorn, 5 to 8 parts of lotus leaves, 1 to 4 parts of medlar and 2 to 5 parts of mango. The invention also provides the preparation method of the diet health-care product. The product disclosed by the invention has a weight-reducing effect, and can be taken by people with essential hypertension, diabetes mellitus, obesity and the like for a long time.

Description

Slimming health product and preparation method thereof
Technical field
The present invention relates to health product technology field, especially a kind of slimming health product and preparation method thereof.
Background technology
The Along with people's growth in the living standard, body weight is generally increased per capita, the corresponding crowd who some obesities occur simultaneously, and the trend that is risen gradually by the also corresponding appearance of a series of disease incidents that obesity is brought.Obesity is the healthy a kind of trophism metabolic disturbance diseases with the unbalance master of being of fat metabolism of harm humans, is result of various factor comprehensive action.Fat very big to people's health hazard property, mainly show fat closely related with multiple diseases such as angiocardiopathy, type ii diabetes, hypertension, dyslipidemia, hyperuricemia, some tumour and sleep disordered breathings.Fat one of the 5 big diseases of serious harm human health of having been classified as by the World Health Organization.
Relevant ways of preventing obesity mainly contains Orally taken product, operative treatment etc. both at home and abroad at present.Lipposuction has wound, and postoperative also has the possibility of bounce-back.Oral diet products mainly are divided into appetite inhibitor, eccritic, promotion metabolism class and blocking-up fat absorption class.The accurate font size fat-reducing medicine composition of mainly losing weight is a sibutramine hydrochloride; Because it possibly cause harm serious adverse such as apoplexy, blood pressure rising, heart rate quickening, apocleisis, insomnia, dysfunction of liver, in October, 2010, Bureau of Drugs Supervision of country announced to stop production and sales use sibutramine preparation and bulk drug.Also have some to adopt the diet products that wash with watercolours is let out effect that have that health also had adverse influence in addition.
Summary of the invention
The present invention is directed to deficiency, propose a kind of slimming health product, have tangible fat-reducing effect.
In order to realize the foregoing invention purpose, the present invention provides following technical scheme: a kind of slimming health product, form by the raw material of following weight portion:
1~4 part of bitter leaves tea
2~5 parts of hawthorn
5~8 parts on lotus leaf
1~4 part of matrimony vine
2~5 parts of mango.
Preferably, the weight portion of said bitter leaves tea is 3 parts.
Preferably, the weight portion of said hawthorn is 2 parts.
Preferably, the weight portion of said lotus leaf is 6 parts.
Preferably, the weight portion of said matrimony vine is 1 part.
Preferably, the weight portion of said mango is 2 parts.
Preferably, these health products are oral agents.
The present invention adopts pure natural plants such as the bitter leaves tea, hawthorn, lotus leaf, matrimony vine, mango of integration of drinking and medicinal herbs; Utilize the active ingredient that they contain; Can regulate the activity of the activity of human body metabolic enzyme, the decomposition that strengthens the fat in the norepinephrine induced lipolysis cell, promotion hormone-sensitive lipase; Can quicken the oxidation Decomposition of body fat tissue, curative effect on obesity is good, persistent is stablized, have no adverse reaction, and bitter leaves tea, matrimony vine still are desirable health food; Taking the health of useful human body for a long time, is a kind of very desirable diet food.
The composition of Chinese medicine compound prescription of the present invention is according to being: containing multiple compositions such as bitter leaves saponin(e, amino acid, vitamin C, flavonoids, caffeine in the bitter leaves tea, multiple efficacies such as hypotensive, reducing blood lipid, fat-reducing are arranged, is main component in the side;
Mango contains various nutrients and vitamin C, mineral matter, also has the artery sclerosis of control and hypertensive effect;
Hawthorn has that long-pendingization of disappearing stagnates, astriction, can promote the digestion of fat food;
That lotus leaf has is clearing heat and detoxicating, the effect of cooling blood and hemostasis;
The effect that matrimony vine has is nourishing liver and kidney, nourish the liver to improve visual acuity can hypotensive, reducing blood lipid, improves immune function of human body.
Slimming health product of the present invention is through the studies on acute toxicity evidence, and is without any side effects.
The method for using of slimming health product of the present invention and consumption: dose of the present invention depends on factors such as concrete formulation, patient's age, health status.As guidance: as Orally taken product, recommending consumption is 10g~20g crude drug/day, has once obeyed before sleeping every night.
The present invention also provides a kind of preparation method of slimming health product, may further comprise the steps:
1., take by weighing each raw material by following weight portion:
1~4 part of bitter leaves tea
2~5 parts of hawthorn
5~8 parts on lotus leaf
1~4 part of matrimony vine
2~5 parts of mango
2., each raw material is mixed the extraction of adding 30%~90% alcohol reflux; Filter, filtrate decompression is concentrated into thick paste, promptly get slimming health product.
Preferably, this preparation method is further comprising the steps of:
3., thick paste is dry, add required auxiliary material or the excipients of oral agents moulding, process finished product.
Preferably, the 2. middle reflux extracting time of step is 2 hours; The relative density of thick paste is 1.10~1.12.
Compared with prior art, the present invention adopts ethanol to carry out the mixture that each raw material of refluxing extraction is formed, and after the filtration filtrating is condensed into thick paste, can obtain slimming health product.Wherein can in thick paste, add required auxiliary material of preparations shaping or excipient, process various oral agents, like tablet, granule, capsule, mixture, pill, oral liquid, syrup or pill etc.Whole manufacture craft is simple, and is easy and simple to handle, is suitable for individual workship or integrated mill and makes.
The specific embodiment
Describe the present invention below in conjunction with specific embodiment, the description of this part only is exemplary and explanatory, should any restriction not arranged to protection scope of the present invention.
The preparation of embodiment 1 capsule
Get bitter leaves tea 300g, hawthorn 200g, lotus leaf 600g, matrimony vine 100g, mango 200g, with the above-mentioned raw materials mixing; Add 13 liters of 70wt% ethanol and carry out refluxing extraction 2 times, each 60min.Filter, it is 1.10 (60 ℃) that filtrate decompression is concentrated into relative density, spray-drying; The auxiliary material that adds an amount of capsule, mixing is granulated, and the capsule of packing into No. 1 promptly gets.
The preparation of embodiment 2 granules
Get bitter leaves tea 100g, hawthorn 500g, lotus leaf 500g, matrimony vine 400g, mango 200g, with the above-mentioned raw materials mixing; Add 14 liters of 80wt% ethanol and carry out refluxing extraction 2 times, each 60min.Filter, it is 1.12 (60 ℃) that filtrate decompression is concentrated into relative density, spray-drying; Add auxiliary materials such as suitable amount of sucrose, starch, granulate, promptly get.
The preparation of embodiment 3 pills
Get bitter leaves tea 400g, hawthorn 200g, lotus leaf 800g, matrimony vine 100g, mango 500g, with the above-mentioned raw materials mixing; Add 16 liters of 60wt% ethanol and carry out refluxing extraction 2 times, each 60min.Filter, it is 1.11 (60 ℃) that filtrate decompression is concentrated into relative density, spray-drying; Add an amount of starch supplementary material, pill promptly gets.
The preparation of embodiment 4 capsules
Get bitter leaves tea 300g, hawthorn 400g, lotus leaf 700g, matrimony vine 200g, mango 300g, with the above-mentioned raw materials mixing; Add 18 liters of 30wt% ethanol and carry out refluxing extraction 2 times, each 60min.Filter, it is 1.12 (60 ℃) that filtrate decompression is concentrated into relative density, spray-drying; Add an amount of starch supplementary material, process capsule, promptly get.
Clinical testing
135 routine obese patients are divided into five groups at random, and average every group 27 example sets up control group and four treatment groups separately, and different with control group is the preparation that the treatment group makes at the foregoing description 1 to embodiment 4 that takes night and morning respectively.
1, be the simple obesity patient in clinical data 135 examples, the course of disease is the shortest 1 year, and is the longest 30 years.Slight fat 30 examples, fat 80 examples of moderate, fat 25 examples of severe.
The clinical physical data of table 1
Figure BDA0000047977190000051
2, diagnosis and criterion of therapeutical effect
2.1, diagnostic criteria according to " practical clinical practice " regulation, 20% [SBW=(height-100) cm * 0.9] of the body weight that is above standard or body mass index are greater than 24.
2.2, fat division and criterion of therapeutical effect be with reference to national combination of Chinese tradiational and Western medicine obesity in 1987
The simple obesity curative effect judging standard that the research seminar is confirmed.
The slight obesity body weight 20~30% that is above standard
The moderate obesity body weight 30~50% that is above standard
The severe obesity is above standard body weight greater than 50%
Produce effects body weight decline >=10kg, waistline minimizing >=10cm
Effective body weight decline >=3kg, waistline minimizing >=4cm
Invalid body weight decline<3kg, waistline minimizing<4cm
2.3, methods of treatment
The treatment group compound Ilex Kudingcha diet food that takes night and morning every day is equivalent to crude drug amount 10g, diet, the no specific (special) requirements of motion at every turn.Statistics fat-reducing result after one month, the result sees table 2
The clinical comparison (%) of respectively organizing curative effect of table 2
Figure BDA0000047977190000061
Can find out that from table 2 apparently higher than control group, total effective rate is at least 78% to the treatment group of each embodiment on fat-reducing effect.Explain that slimming health product of the present invention has tangible antiobesity action.
It below only is preferred implementation of the present invention; Should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the principle of the invention; Can also make some improvement and retouching, these improvement and retouching also should be regarded as protection scope of the present invention.

Claims (10)

1. slimming health product, form by the raw material of following weight portion:
Figure FDA00001628355800011
2. slimming health product as claimed in claim 1 is characterized in that: the weight portion of said bitter leaves tea is 3 parts.
3. slimming health product as claimed in claim 1 is characterized in that: the weight portion of said hawthorn is 2 parts.
4. slimming health product as claimed in claim 1 is characterized in that: the weight portion of said lotus leaf is 6 parts.
5. slimming health product as claimed in claim 1 is characterized in that: the weight portion of said matrimony vine is 1 part.
6. slimming health product as claimed in claim 1 is characterized in that: the weight portion of said mango is 2 parts.
7. slimming health product as claimed in claim 1 is characterized in that: these health products are oral agents.
8. the preparation method of a slimming health product may further comprise the steps:
1., take by weighing each raw material by following weight portion:
2., each raw material is mixed the extraction of adding 30%~90% alcohol reflux; Filter, filtrate decompression is concentrated into thick paste, promptly get slimming health product.
9. preparation method as claimed in claim 8 is characterized in that: this preparation method is further comprising the steps of:
3., thick paste is dry, add the required auxiliary material of oral agents moulding, process finished product.
10. like claim 8 or 9 described preparation methods, it is characterized in that: the 2. middle reflux extracting time of step is 2 hours; The relative density of thick paste is 1.10~1.12.
CN201110046299A 2011-02-25 2011-02-25 Diet health-care product and preparation method thereof Expired - Fee Related CN102132870B (en)

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Publication number Priority date Publication date Assignee Title
CN102430022A (en) * 2011-12-30 2012-05-02 苏州爱斯欧蒂生物科技有限公司 Weight-reducing health-care product and preparation method thereof
CN102579643A (en) * 2012-02-27 2012-07-18 苏州爱斯欧蒂生物科技有限公司 Novel effective weight-losing medicine
CN107432463A (en) * 2016-05-25 2017-12-05 辽宁药联制药有限公司 A kind of slimming health product and preparation method thereof

Citations (3)

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Publication number Priority date Publication date Assignee Title
CN101274042A (en) * 2008-05-15 2008-10-01 天科仁祥技术(北京)有限责任公司 Medicament composition for curing hyperlipemia and method of preparing the same
CN101595927A (en) * 2008-06-06 2009-12-09 刘泳宏 A kind of natural lung-nourishing lipopenicillinase, hypoglycemic, blood-pressure decreasing tea and preparation method
CN101623038A (en) * 2008-07-08 2010-01-13 刘泳宏 Natural five-color fat-reducing dietic medicinal tea beverage and preparation method

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
CN101274042A (en) * 2008-05-15 2008-10-01 天科仁祥技术(北京)有限责任公司 Medicament composition for curing hyperlipemia and method of preparing the same
CN101595927A (en) * 2008-06-06 2009-12-09 刘泳宏 A kind of natural lung-nourishing lipopenicillinase, hypoglycemic, blood-pressure decreasing tea and preparation method
CN101623038A (en) * 2008-07-08 2010-01-13 刘泳宏 Natural five-color fat-reducing dietic medicinal tea beverage and preparation method

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