CN102362936B - Application of amorphophallus blume extract, and medicine and healthcare product solid preparation and beverage of amorphophallus blume extract - Google Patents

Application of amorphophallus blume extract, and medicine and healthcare product solid preparation and beverage of amorphophallus blume extract Download PDF

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CN102362936B
CN102362936B CN201110329564.6A CN201110329564A CN102362936B CN 102362936 B CN102362936 B CN 102362936B CN 201110329564 A CN201110329564 A CN 201110329564A CN 102362936 B CN102362936 B CN 102362936B
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rhizoma amorphophalli
extract
medicine
amorphophalli virosi
virosi
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CN102362936A (en
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黄柱联
钟国华
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Abstract

The invention disclose application of amorphophallus blume extract, and a medicine and healthcare product solid preparation and a medicine and healthcare product beverage of the amorphophallus blume extract, in particular the application of the amorphophallus blume extract to the medicine and healthcare preparation for preventing and treating prostatic disorders, and the medicine and healthcare product solid preparation and the medicine and healthcare product beverage for preventing and assisting in treating prostatic disorders, which are prepared from the amorphophallus blume extract. Through research, amorphophallus blume has a good curative effect of preventing and assisting in treating prostatic disorders; the prepared medicine and healthcare product solid preparation and the prepared medicine and healthcare product beverage have the effects of tonifying spleen, relieving internal heat or fever and dissipating binds, preventing and assisting in treating prostatic disorders and other diseases, and are the better medicine and nutritional health food product.

Description

The purposes of Rhizoma Amorphophalli virosi extract and medicine thereof and health product solid preparation, beverage preparation
Technical field
The invention belongs to medicine and field of health care food, specifically relate to the purposes of Rhizoma Amorphophalli virosi extract, and Rhizoma Amorphophalli virosi is used in to the application in prevention and medicine and health product solid preparation and the beverage preparation of auxiliary treatment prostatosis.
Background technology
Prostatosis be a kind of sickness rate high, treat thorny disease.It generally comprises acute and chronic prostatitis, bacterial prostatitis, prostatic hyperplasia, carcinoma of prostate etc., is puzzlement male's common disease.The common sympton of prostatosis is frequent micturition, urgent micturition, dysurea, drips white, lumbago, even causes sexual dysfunction etc.Prostatosis clinical symptoms complexity, normal easily recurrence.
At present, the primary treatment means of prostatosis are medicine and operation etc.But due to the special physiological structure of prostate, common drug is difficult to enter its inside through the hard adipose membrane of one deck of prostate coated outside; Moreover, due to the special pathogeny of prostatosis, causing class of medications poor effect, side effect is very large.And operative treatment not only cost is very high, therapeutic effect is not good yet, and side effect is large, very painful after treatment.In Chinese Traditional Medicine, although many for the effective plant amedica of prostate, corresponding clinical research and excess syndrome effect are more limited, and DeGrain in practice.
Summary of the invention
In order to meet people's demand, the object of the present invention is to provide the application of a kind of Rhizoma Amorphophalli virosi extract in medicine and the health-care preparation of prevention and auxiliary treatment prostatosis, by add Rhizoma Amorphophalli virosi extract in medicine and health-care preparation, can prevent and improve the symptom of chronic prostatitis and prostatic hyperplasia.
Another one object is: a kind of prevention and the medicine of auxiliary treatment prostatosis and the solid preparation of health product and beverage preparation are provided.
The technical scheme that the present invention takes is:
The application of Rhizoma Amorphophalli virosi extract in medicine and the health-care preparation of prevention and auxiliary treatment prostatosis.Rhizoma Amorphophalli virosi composition has the effect of soothing liver and strengthening spleen, detoxicating and resolving stagnation of pathogens, and in addition, inventor is through studying for a long period of time, and Rhizoma Amorphophalli virosi extract can also play good effect to prevention auxiliary treatment prostatosis.
Medicine and the health product solid preparation of prevention and auxiliary treatment prostatosis, its main component comprises Rhizoma Amorphophalli virosi extract and adjuvant, this adjuvant is specifically as follows acceptable pharmaceutic adjuvant.
Its adjunct ingredient comprises corn starch, microcrystalline Cellulose and carboxymethyl starch sodium.
Further, the ratio of weight and number of Rhizoma Amorphophalli virosi extract, corn starch, microcrystalline Cellulose and carboxymethyl starch sodium, take gross weight as every 10 grams, Rhizoma Amorphophalli virosi extract is 3.5~5 grams, corn starch is 3.5~5 grams, and microcrystalline Cellulose is 0.3~0.7 gram, and carboxymethyl starch sodium is 0.6~0.9 gram.
As preferred implementation; Rhizoma Amorphophalli virosi extract is 12 grams; corn starch 13g, microcrystalline Cellulose 2g, carboxymethyl starch sodium 3g, major ingredient Rhizoma Amorphophalli virosi extract and other a few taste adjuvants were pulverized to No. eight sieves (150 order); mix homogeneously; granulation on granulator; through granulate, evenly subpackage, makes 100 capsules finished products.As film-making agent, made granule can be carried out to granulate tabletting, more coated processing, can be made into 100 health care finished products.
Medicine and the health product beverage preparation of prevention and auxiliary treatment prostatosis, its main component comprises Rhizoma Amorphophalli virosi extract and water, and Rhizoma Amorphophalli virosi extract is soluble in water, and beverage is made.Rhizoma Amorphophalli virosi composition has soothing liver and strengthening spleen; Detoxicating and resolving stagnation of pathogens, the multiple effects such as prevention auxiliary treatment prostatosis.
Further, medicine and health product beverage preparation, its composition also includes oligofructose.Oligofructose is a kind of natural active matter.Have regulating intestinal canal flora, propagation bacillus bifidus, promotes the absorption of calcium, regulates blood fat, immunomodulating, the health cares such as dental caries.Meanwhile, oligofructose or novel sweetener.
Its composition also includes Mel, and Mel has good medical effect and the strong effect of nutrition, can supplement the nutrient substance such as trace element, vitamin of needed by human body, but also can in and body in free acid, make body fluid keep acid-base balance, in addition, Mel also has good antiinflammatory action.
As preferred implementation, beverage ingredient comprises Rhizoma Amorphophalli virosi extract, oligofructose, Mel and water.
Specifically preferred proportion is, medicine and the health product beverage preparation of a kind of prevention and auxiliary treatment prostatosis contain 10~150 grams of Rhizoma Amorphophalli virosi extracts in every liter of beverage, 20~70 grams of Mel, and 10~40 grams of oligofructoses, surplus is water.In addition, can also add 0.05~0.25 gram, ascorbic acid.
In addition, further, also include 0.2~1.5 gram of malic acid in the composition in every liter of beverage, malic acid has the effect of adjusting taste.
The invention has the beneficial effects as follows: through inventor's research, Rhizoma Amorphophalli virosi has good curative effect to prevention and auxiliary treatment prostatosis, and made medicine and health product solid and beverage preparation, have soothing liver and strengthening spleen; Detoxicating and resolving stagnation of pathogens, the diseases such as prevention auxiliary treatment prostate, are preferably medicine and nutritional health foods of one.
The specific embodiment
Mentioned Rhizoma Amorphophalli virosi extract in of the present invention is to extract and form in Rhizoma Amorphophalli virosi.
Rhizoma Amorphophalli virosi is that Araeceae (Araceae) Mo Yu family mill taro belongs to (Amorphophallus Blume) plant, and its formal name used at school is wart handle mill taro (Amorphallus virosus N.e.Brown).Araeceae has more than 2000 kinds of 115 genus, is mainly distributed in subtropical and tropical zones, and there are 206 kinds of 25 genus in China.In Araeceae, the Rhizoma amorphophalli platymiscium whole world has 163 kinds, and China mill taro has 18 kinds, and wherein 9 is endemic species.Wart handle mill taro is mainly distributed in Guangdong, Guangxi, Hainan, the Yunnan Si Sheng of China.The local and special products of one bands such as Rhizoma Amorphophalli virosi is the Taishan, Guangdong Province, it is flat to open, Enping City, Yangjiang, among the peoplely treat the aspect such as gastropathy, hepatitis with it and have unique curative effect.
Rhizoma Amorphophalli virosi is recorded in " China's book on Chinese herbal medicine ", " Guangdong Chinese medicinal herbal " etc., but is not applied in up to now Rhizoma Amorphophalli virosi granule, tablet, capsule, the beverage report of prevention and auxiliary treatment prostatosis about Rhizoma Amorphophalli virosi.
In addition, in " Rhizoma Amorphophalli virosi chemical composition and pharmacology activity research thereof " literary composition of Guangdong University of Technology, also describe the information such as the chemical composition of Rhizoma Amorphophalli virosi and Rhizoma Amorphophalli virosi extract in detail, in its Rhizoma Amorphophalli virosi extract, separate and can draw 7 main compound, by Mass Spectrometric Identification its structure, they are respectively stigmasterol, β-sitosterol, Palmic acid, ethyl palmitate, hexadecylic acid monoglyceride, 9,12,15-triolefin Ethyl Stearate, behenic acid ethyl ester.Above chemical composition all obtains first in Rhizoma Amorphophalli virosi.In each component of Rhizoma Amorphophalli virosi column chromatography rough segmentation, GC-MS analysis has been carried out in petroleum ether eluent position, identify altogether 25 materials, they are respectively alkane (7 kinds), alkene (2 kinds), alcohol (3 kinds), ketone (3 kinds), aldehyde (2 kinds), acid (3 kinds), ester (3 kinds), aromatic (3 kinds).The mother solution of Guangdong University of Technology's Master of engineering academic dissertation after to component H recrystallization carried out GC mono-MS and analyzed, identify 7 materials, they are respectively: ten dihydro one IH mono-chrysanthemums (dibenzo is luxuriant), tolyl) alkene 1 in the ninth of the ten Heavenly Stems 1 [2 one bark mutters] propane, 2 monobutyl dicyclos " 2, 2, 2 one phenyl one dicyclos [3, 2, 1) heptane, 3 one propyl group one 1 one cyclohexene, 1 one [4-l " pungent one 2 one alkene, anti-one 8 one isopropyl dicyclos [4, 3, 0], 7 one acetenyls 1, 4a mono-dimethyl one 4a, 5, 6, 7, 8, sa mono-or six hydrogen one 2[IH] Cai's ketone.The later eluent part of component VI is carried out to GC mono-MS to be analyzed, identify six materials, they are respectively: propyl group fluoro-phosphoric acid one 4 monomethyl Hexalin are cruel, 2 (3) one benzo miaow ketone, 1 one (2 one coloured glaze base benzo miaow) acetone, phthalic acid two fourths are cruel, different pungent cruel, 2,2 ' one dibenzo of phthalic acid two is instigateed.On to the basis of Rhizoma Amorphophalli virosi pharmacology activity research and chemical constitution study, the effective ingredient of its hepatoprotective is inquired into.9,12,15 1 triolefin stearic acid second are extremely one of its hepatoprotective effective ingredient, and other effective ingredient may be present in water-soluble part (the insoluble part of acetone).
In above-mentioned " Rhizoma Amorphophalli virosi chemical composition and pharmacology activity research thereof " literary composition, same, do not have the Rhizoma Amorphophalli virosi granule, tablet, capsule, the beverage that are applied in prevention and auxiliary treatment prostatosis about Rhizoma Amorphophalli virosi to report.
But, prove through inventor's research experiment, utilize the made granule of Rhizoma Amorphophalli virosi extract, beverage, can play the diseases such as prevention auxiliary treatment prostate, also there is effect of life lengthening.
Therefore, the invention provides the application of a kind of Rhizoma Amorphophalli virosi extract in medicine and the health-care preparation of prevention and auxiliary treatment prostatosis.
Wherein, Rhizoma Amorphophalli virosi extract can adopt as the extracting method described at " Rhizoma Amorphophalli virosi chemical composition and pharmacology activity research thereof " literary composition, also can adopt other extracting method, such as the method described in the following inventor, main purpose is the macromole such as starch, the albumen impurity in Rhizoma Amorphophalli virosi rhizome to isolate.
The inventor's Rhizoma Amorphophalli virosi method for preparing extractive is, first Rhizoma Amorphophalli virosi (rhizome) is pulverized, decocting boils repeatedly, merge decoction liquor, through high speed separator, the macromole such as starch, albumen impurity is isolated, separating medium is filtered, filter by hollow-fibre ultrafiltration device again, obtain the supernatant liquid containing Rhizoma Amorphophalli virosi, liquid vacuum is condensed into fluid extract, obtain required Rhizoma Amorphophalli virosi extract material.
In said method, Rhizoma Amorphophalli virosi is ground into the coarse powder of 60 order left and right, it is 3-5 time that decocting boils number of times, each decocting time is more than 4 hours, select especially the disk centrifuge of 2300~2500 revs/min, 0.4~0.5 micron of described filter pore size, it is 130000~160000 that described hollow-fibre ultrafiltration device is selected molecular cut off.
Specifically prepare the embodiment of extract:
Get 10000 grams of dry Rhizoma Amorphophalli virosi (rhizome) section, be ground into 60 order coarse powder, decocting boils three times, add water 100 liters at every turn, boil 4 o'clock at every turn, extrude medicinal liquid, discard residue, merge three times decoction liquor, be cooled to 10 ℃, through disk centrifuge (2400 revs/min) separation at a high speed, by starch, the macromole impurity such as albumen are isolated, separating medium is filtered through 0.5 micron pore size accurate filter, filter by the hollow-fibre ultrafiltration device of 150000 molecular cut offs again, obtain the supernatant liquid containing Rhizoma Amorphophalli virosi, liquid vacuum (450mmHg) is condensed into 5000 grams of fluid extracts.
By said process and step, can draw Rhizoma Amorphophalli virosi extract required for the present invention.
Rhizoma Amorphophalli virosi extract is to use in the preparation of relevant medicine and health food in the concrete application of prevention and auxiliary treatment prostatosis, specifically comprises solid preparation or beverage preparation, can be applied on medicine, also can be applied on health food.
Wherein, the invention provides medicine and the health product solid preparation of a kind of prevention and auxiliary treatment prostatosis.This solid preparation can be granule, sheet or capsule, and its main component comprises Rhizoma Amorphophalli virosi extract and adjuvant.
Wherein, this adjuvant is specially acceptable pharmaceutic adjuvant, and the ratio of main component Rhizoma Amorphophalli virosi extract wherein can be unrestricted, as long as form solid preparation with adjuvant.
Further, the ratio of weight and number of Rhizoma Amorphophalli virosi extract, corn starch, microcrystalline Cellulose and carboxymethyl starch sodium, take gross weight as every 10 grams, Rhizoma Amorphophalli virosi extract is 3.5~5 grams, corn starch is 3.5~5 grams, and microcrystalline Cellulose is 0.3~0.7 gram, and carboxymethyl starch sodium is 0.6~0.9 gram.
As preferred implementation; ratio of weight and number: Rhizoma Amorphophalli virosi extract is 12 grams; corn starch 13g, microcrystalline Cellulose 2g, carboxymethyl starch sodium 3g, major ingredient Rhizoma Amorphophalli virosi extract and other a few taste adjuvants were pulverized to No. eight sieves (150 order); mix homogeneously; granulation on granulator; through granulate, evenly subpackage, makes 100 capsules finished products.As film-making agent, made granule can be carried out to granulate tabletting, more coated processing, can be made into 100 health care finished products.
In addition, the invention provides medicine and the health product beverage preparation of a kind of prevention and auxiliary treatment prostatosis, its main component comprises Rhizoma Amorphophalli virosi extract and water, Rhizoma Amorphophalli virosi extract is soluble in water, the beverage that is made, the content ratio of Rhizoma Amorphophalli virosi extract is the amount doesn't matter, there is no concrete restriction at this, it depends on manufactured goods is concentrated solution or diluent, and different products is set demand and determines.
This beverage preparation can only be mixed by above-mentioned Rhizoma Amorphophalli virosi extract and water bi-material, can be played by Rhizoma Amorphophalli virosi extract the effect of prevention and auxiliary treatment prostatosis, certainly, also can, by adding other material, play the effect that increases function or be in harmonious proportion taste.
Such as, in medicine and health product beverage preparation, its composition can also include oligofructose.Oligofructose is a kind of natural active matter.Have regulating intestinal canal flora, propagation bacillus bifidus, promotes the absorption of calcium, regulates blood fat, immunomodulating, and the health cares such as dental caries, meanwhile, oligofructose is also novel sweetener.The not circumscribed of concrete content of oligofructose, same, it depends on manufactured goods is concentrated solution or diluent, and different taste proportioning and determining.
Further, its composition also includes Mel, Mel has good medical effect and the strong effect of nutrition, can supplement the nutrient substance such as trace element, vitamin of needed by human body, but also can in and body in free acid, make body fluid keep acid-base balance, in addition, Mel also has good antiinflammatory action, in like manner, the content of Mel can not be subject to too many restriction, only need to coordinate from mouthfeel appropriate.
Further, as preferred implementation, beverage ingredient comprises Rhizoma Amorphophalli virosi extract, oligofructose, Mel, ascorbic acid and water, in beverage ingredient, there is above-mentioned substance simultaneously, not only mouthfeel is good, and possess Rhizoma Amorphophalli virosi extract, oligofructose and three kinds of materials of Mel simultaneously, each composition synergism in beverage, make it to be of value to soothing liver and strengthening spleen, detoxicating and resolving stagnation of pathogens, the diseases such as prevention auxiliary treatment prostate, also there is effect of life lengthening, be preferably nutritious and healthy drink of one, this product is delicious good to eat, and old children is all suitable.
In addition, in above-mentioned made beverage, can also add such as preservative substances such as ascorbic acid, play anticorrosion effect of guaranteeing the quality.
Specifically preferred proportion is, medicine and the health product beverage preparation of a kind of prevention and auxiliary treatment prostatosis contain 10~150 grams of Rhizoma Amorphophalli virosi extracts in every liter of beverage, 20~70 grams of Mel, and 10~40 grams of oligofructoses, surplus is water.In addition, 0.05~0.25 gram, ascorbic acid can also be added, certainly, other material can also be added according to the actual needs.
In addition, further, also include 0.2~1.5 gram of malic acid in the composition in every liter of beverage, malic acid has the effect of adjusting taste.
Below provide two by Rhizoma Amorphophalli virosi from raw material to embodiment and the eating effect of making finished product, for reference.
Embodiment 1(prepares solid preparation):
Get 10000 grams of dry Rhizoma Amorphophalli virosi sections, be ground into 60 order coarse powder, decocting boils three times, add water 100 liters at every turn, boil 4 o'clock at every turn, extrude medicinal liquid, discard residue, merge three times decoction liquor, be cooled to 10 ℃, through disk centrifuge (2400 revs/min) separation at a high speed, the macromole such as starch, albumen impurity isolated, separating medium is filtered through 0.5 micron pore size accurate filter, filter by the hollow-fibre ultrafiltration device of 150000 molecular cut offs again, obtain the liquid containing Rhizoma Amorphophalli virosi, liquid vacuum (450mmHg) is condensed into 5000 grams of fluid extracts; Contain 0.5~0.6 gram of the dry cream of Rhizoma Amorphophalli virosi extract by every gram of pill; dry; wear into fine powder; sieve, major ingredient Rhizoma Amorphophalli virosi extract and other a few taste adjuvants were pulverized to No. eight sieves (150 order), mix homogeneously; granulation on granulator; through granulate, evenly subpackage, makes 100 capsules finished products.As film-making agent, made granule can be carried out to granulate tabletting, more coated processing, can be made into 100 health care finished products, be equivalent to crude drug 75g each serving consumption, every twice-daily.
Embodiment 2(prepares beverage preparation):
Get 10000 grams of dry Rhizoma Amorphophalli virosi sections, be ground into 60 order coarse powder, decocting boils three times, add water 100 liters at every turn, boil 4 o'clock at every turn, extrude medicinal liquid, discard residue, merge three times decoction liquor, be cooled to 10 ℃, through disk centrifuge (2400 revs/min) separation at a high speed, by starch, the macromole impurity such as albumen are isolated, separating medium is filtered through 0.5 micron pore size accurate filter, filter by the hollow-fibre ultrafiltration device of 150000 molecular cut offs again, obtain the supernatant liquid containing Rhizoma Amorphophalli virosi, liquid vacuum (450mmHg) is condensed into 5000 grams of fluid extracts, this fluid extract is added to 25000 grams of Mel, 10000 grams of oligofructoses, 400 grams of benzene fruit acid, 50 grams of ascorbic acid, 120 grams of essence, add water to 500 liters, pH value is 4, and after subpackage, 80 ℃ of water-bath sterilizations 30 minutes, are cooled fast to room temperature.Can obtain Rhizoma Amorphophalli virosi health beverage.
Granule, the beverage made with formula noted earlier, take continuously 2~4 weeks, take the urine of the discomfort of urinating, burning sensation, frequent micturition, urgent micturition, dysurea etc., abnormal color of urine, muddiness, white, dysurea as treatment index, above symptom alleviates as effectively, above symptom disappears completely for curing, through 50 routine Patients with Chronic Prostatitis checkings, above-mentioned symptom has in various degree and alleviates, total effective rate 100%.
The present invention is except above-mentioned embodiment, and other equivalent technical solutions also should, within its protection domain, be narrated at this no longer one by one.

Claims (10)

1. the application of Rhizoma Amorphophalli virosi extract in medicine and the health-care preparation of prevention and auxiliary treatment prostatosis, being obtained by being prepared as follows method of this Rhizoma Amorphophalli virosi extract, first Rhizoma Amorphophalli virosi rhizome is pulverized, decocting boils repeatedly, merge decoction liquor, through high speed separator, the macromole such as starch, albumen impurity is isolated, separating medium is filtered, filter by hollow-fibre ultrafiltration device again, obtain the supernatant liquid containing Rhizoma Amorphophalli virosi, liquid vacuum is condensed into fluid extract, obtains required Rhizoma Amorphophalli virosi extract material.
2. medicine and the health product solid preparation of a prevention and auxiliary treatment prostatosis, it is characterized in that: its composition is made up of Rhizoma Amorphophalli virosi extract and adjuvant, being obtained by being prepared as follows method of this Rhizoma Amorphophalli virosi extract, first Rhizoma Amorphophalli virosi rhizome is pulverized, decocting boils repeatedly, merge decoction liquor, through high speed separator by starch, the macromole impurity such as albumen are isolated, separating medium is filtered, filter by hollow-fibre ultrafiltration device again, obtain the supernatant liquid containing Rhizoma Amorphophalli virosi, liquid vacuum is condensed into fluid extract, obtain required Rhizoma Amorphophalli virosi extract material.
3. medicine and the health product solid preparation of a kind of prevention according to claim 2 and auxiliary treatment prostatosis, is characterized in that: its adjunct ingredient comprises corn starch, microcrystalline Cellulose and carboxymethyl starch sodium.
4. medicine and the health product solid preparation of a kind of prevention according to claim 3 and auxiliary treatment prostatosis, it is characterized in that: the ratio of weight and number of Rhizoma Amorphophalli virosi extract, corn starch, microcrystalline Cellulose and carboxymethyl starch sodium, take gross weight as every 10 grams, Rhizoma Amorphophalli virosi extract is 3.5~5 grams, corn starch is 3.5~5 grams, microcrystalline Cellulose is 0.3~0.7 gram, and carboxymethyl starch sodium is 0.6~0.9 gram.
5. medicine and the health product beverage preparation of a prevention and auxiliary treatment prostatosis, it is characterized in that: its main component comprises Rhizoma Amorphophalli virosi extract and water, Rhizoma Amorphophalli virosi extract is soluble in water, being obtained by being prepared as follows method of this Rhizoma Amorphophalli virosi extract, first Rhizoma Amorphophalli virosi rhizome is pulverized, decocting boils repeatedly, merge decoction liquor, through high speed separator by starch, the macromole impurity such as albumen are isolated, separating medium is filtered, filter by hollow-fibre ultrafiltration device again, obtain the supernatant liquid containing Rhizoma Amorphophalli virosi, liquid vacuum is condensed into fluid extract, obtain required Rhizoma Amorphophalli virosi extract material.
6. medicine and the health product beverage preparation of a kind of prevention according to claim 5 and auxiliary treatment prostatosis, is characterized in that: its composition also includes oligofructose.
7. according to a kind of prevention described in claim 5 or 6 and medicine and the health product beverage preparation of auxiliary treatment prostatosis, it is characterized in that: its composition also includes Mel.
8. medicine and the health product beverage preparation of a kind of prevention according to claim 5 and auxiliary treatment prostatosis, is characterized in that: beverage ingredient comprises Rhizoma Amorphophalli virosi extract, oligofructose, Mel and water.
9. medicine and the health product beverage preparation of a kind of prevention according to claim 8 and auxiliary treatment prostatosis, is characterized in that: in every liter of beverage, contain 10~150 grams of Rhizoma Amorphophalli virosi extracts, and 20~70 grams of Mel, 10~40 grams of oligofructoses, surplus is water.
10. medicine and the health product beverage preparation of a kind of prevention according to claim 9 and auxiliary treatment prostatosis, is characterized in that: in the composition in every liter of beverage, also include 0.2~1.5 gram of malic acid.
CN201110329564.6A 2011-10-26 2011-10-26 Application of amorphophallus blume extract, and medicine and healthcare product solid preparation and beverage of amorphophallus blume extract Expired - Fee Related CN102362936B (en)

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戴馨仪等."益肝"对迁延性慢性病毒性肝炎免疫功能的影响——附180例疗效观察.《广州中医药大学学报》.1984,(第2期),
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