CN103550333A - Composition for appetizing and reducing blood pressure - Google Patents

Composition for appetizing and reducing blood pressure Download PDF

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Publication number
CN103550333A
CN103550333A CN201310505972.1A CN201310505972A CN103550333A CN 103550333 A CN103550333 A CN 103550333A CN 201310505972 A CN201310505972 A CN 201310505972A CN 103550333 A CN103550333 A CN 103550333A
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China
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extract
appetizing
composition
niuganguo
fructus
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CN201310505972.1A
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Inventor
韦晓
龚家强
陶玲云
李永锋
傅汝毅
农卫良
郑贵华
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Guangxi Doctor Hai Yi Information Technology Co Ltd
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Guangxi Doctor Hai Yi Information Technology Co Ltd
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Publication of CN103550333A publication Critical patent/CN103550333A/en
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The invention relates to an appetizing and blood sugar reducing composition prepared by processing natural plants which serve as raw materials. The composition is prepared by uniformly mixing phyllanthus emblica, mulberry and hawthorn extract in a mass ratio of 2:2:1 or 1:1:1. The composition has excellent effects of reducing blood sugar, reducing blood fat, reducing blood pressure, resisting arrhythmia, moistening lung for removing phlegm, helping produce saliva and slake thirst, promoting appetite, nourishing and strengthening, nourishing heart and improving intelligence and the like. Furthermore, the components of the composition are natural plants, safe and reliable, do not have toxic or side effect, and have the characteristics of various functions, rich nutrition, appetite promotion, convenience in eating, excellent taste and the like.

Description

A kind of appetizing blood pressure reducing composition
Technical field
The invention belongs to health food, biomedicine field, be specifically related to the appetizing blood pressure reducing composition that a kind of Niuganguo by natural origin, Fructus Mori and Fructus Crataegi compositions form.
Background technology
Diabetes are one group and take the metabolic disease that hyperglycemia is feature, and long-standing hyperglycemia during diabetes, can cause various tissues, particularly eye, kidney, heart, blood vessel, neural chronic lesion, dysfunction.At present, probably there are 200,000,000 diabeticss in the whole world, and this numeral is also in cumulative year after year.Second largest country of diabetics total number of persons is suffered from as the whole world by China, and the treatment of diabetes is just paid close attention to by increasing people.For the treatment of hyperglycemia, generally take the hypoglycemic chemical drugs of long-term taking now, but so can bring certain toxic and side effects for human body.Therefore, utilize modern study technology to develop natural plants, produce the natural health-care products of integration of edible and medicinal herbs, can use by assistant chemical medicine, thereby the dosage that reduces chemicals alleviates slight diabetics for the dependence of hypoglycemic drug, the misery of reduction of patient simultaneously.
Summary of the invention
For the auxiliary symptom of improving diabetics, reduction of patient is painful, the invention provides a kind of hypoglycemic compositions.This compositions has the effects such as blood sugar lowering, blood fat reducing, blood pressure lowering, arrhythmia, moistening the lung and resolving phlegm, promoting the production of body fluid to quench thirst, appetite stimulator, strengthening by means of tonics, the heart nourishing and intellengence improving, take the natural plants such as Niuganguo, Fructus Mori and Fructus Crataegi as primary raw material formation.
Technical scheme of the present invention is as follows:
By the extract of Niuganguo, Fructus Mori and Fructus Crataegi, 2:2:1 or 1:1:1 mix homogeneously form in mass ratio.
Above-described Niuganguo, has another name called Phyllanthus emblica L., latin name: Phyllanthus emblica L. is Euphorbiaceae, the perennial defoliation small arbor of Leafflower or shrub.More than 10 meters of this plant Gao Keda, branch taupe.Single leaf alternate, 10-23 pairs, line up two row, and be born on lateral leaflets, the utmost point is like winglike compound leaf, and leaf wire is long oval, long 2cm, tip circle is blunt, the short almost stockless of petiole, full edge, blade face strong green.Monoecy, brightly yellowish color, is born in sprig, bottom axil, and male flower is most, the stalk that tool is elongated; Female flower is few, and tool does not obstruct, and ovary is upper.Fruit oblate spheroid, is unconspicuous 6 ribs, yellow green, and diameter 2-2.5cm, peel meat, has tart flavour, and smooth surface is glossy, endocarp os osseum matter, 6 pieces, seed, brown.Florescence and fructescence, according to type and from different places the florescence had the spring to open once, spring and autumn twice flower and several situations of perpetual bloom, at approximately 1-1.5 months florescences, percentage of fertile fruit is high.General early-maturing variety is ripe July, and medium variety 8-JIUYUE is ripe, and late variety is ripe in October, and the February in next year of second bloom is ripe successively, but concentrates the period of maturation in the winter time.Biennial bearing is not obvious.According to < < Compendium of Materia Medica > >, record, Niuganguo can the strong gas of tonification, hair color, cure mainly wind deficiency-heat gas, asthma and cough, for a long time clothes make light of one's life by commiting suicide, life lengthening.And there is blood pressure lowering fat-reducing, slow down aging, the 35 kinds of therapeutic efficiencies such as wetting one's whistle, separate metal and stone poison, blacking hair and beauty that relieve inflammation or internal heat, by Ministry of Public Health, classified as the healthy fruit of " being food and medicine ".Phyllanthus emblica L. is contained containing 18 seed amino acids of human body institute palpus, 16 kinds of trace element, abundant vitamin C and SOD, organic selenium, wherein Vitamin C content is up to 0.6-1.56%, than taller 5 times of " king of vitamin C " Fructus actinidiae chinensis, 100 times of Fructus Mali pumilaes, 25-50 times, mandarin orange, and contained vitamin C quite stable, also preserve 80%-98% through high temperature with after shining for a long time, Pesticides Testing is zero, is not containing one of best fruit of pesticide composition in current fruits.Through modern medicine study, confirm, gastric cancer can obviously be treated and prevent to Niuganguo, and hepatitis B, hyperlipidemia, hypertension, hyperglycemia etc. are all had to good curative effect.Treatment throat discomfort, tobacco and wine excessively, biliary tract ascarid angor etc., get instant result especially.
Above-described Fructus Mori, have another name called Fructus Mori, and latin name Fructus Mori belongs to Moraceae, is the mature fruit of Moraceae deciduous tree mulberry, is collective fruit, by most drupel set, is formed, and is Long Circle, long 1-2cm, diameter 0.5-0.8cm.Yellowish-brown, brownish red are to mulberry, and (after more rare color maturation, being creamy white), has short infructescence stalk.Drupel oval, slightly flat, be about 2mm, wide about 1mm, 4 pieces of outer tool meat tapels.Feeble QI, the micro-acid of taste and sweet.Fructus Mori both can food, can be used as medicine again, and the traditional Chinese medical science is thought the acid of Fructus Mori sweet in the mouth, and cold nature, enters the heart, liver, kidney channel, is strengthening by means of tonics, the good fruit of the heart nourishing and intellengence improving.Having enriches blood invigorates blood circulation, nourishing YIN and invigorating YANG, and promoting the production of body fluid to quench thirst, the effect such as intestine moistening is dry, cures mainly deficiency of YIN-blood and having a dizzy spell of causing, tinnitus cardiopalmus, irritated insomnia, soreness of the waist and knees, early whitening of beard and hair, the xerostomia of quenching one's thirst, the diseases such as constipation with dry stool.Simultaneously, Fructus Mori also have abundant nutrition, modern study confirms, in Fructus Mori fruit, contain the compositions such as abundant activated protein, vitamin, aminoacid, carotene, mineral, resveratrol, anthocyanidin, nutrition is 5-6 times of Fructus Mali pumilae, be 4 times of Fructus Vitis viniferae, there is multiple efficacies, by medical circle, be described as " the best health fruit of 21st century ".Often eat Fructus Mori and can significantly improve body immunity, there is slow down aging, the effect of looks improving and the skin nourishing.
Above-described Fructus Crataegi, has another name called fruit, red Chinese date in Fructus Pyri Pashiae, Fructus Pyracanthae, large Fructus Crataegi, mountain, latin name: Crataegus pinnatifida is Rosaceae, Maloideae, the fruit of may.This plant defoliation dungarunga.The close life of branch, has spinelet, and sprout has pubescence.Sprig puce, old branch taupe.Blade triangular shape is avette avette to rib shape, long 2-6cm, and wide 0.8-2.5cm, base portion cuts shape or wide wedge shape, and respectively there are 3-5 pinniform drastic crack sheets both sides, and 1 pair of sliver division of base portion is darker, and there is irregular sharp sawtooth at edge.Compound corymb, peduncle, anthocaulus have long pubescence; Floral white, has distinctive odor.Diameter 1.5cm; Calyx tube has long pubescence outward, and the inside and outside two sides of sepal is without hair or inner face top hairiness.Melonidum peony, subsphaeroidal.5-June of florescence, really 9-October of phase.Modern study Fructus Crataegi, containing materials such as saccharide, protein, fat, vitamin C, carotene, starch, malic acid, citric acid, calcium and ferrum, has the effects such as blood fat reducing, blood pressure, heart tonifying and arrhythmia.Flavone compound vitexin in Fructus Crataegi, is the medicine that a kind of antitumaous effect is stronger, and Fructus Crataegi extract all has certain inhibitory action to cancerous cell tumor growth, propagation and infiltration metastasis.
The preparation method of appetizing hypoglycemic composition of the present invention, comprises extraction, pulverizing, mixing, packing and irradiation, and its concrete preparation process is as follows:
1) extract: Niuganguo is cleaned after enucleation, added respectively water with clean Fructus Mori, decoct to ripe rotten, the ratio of raw material and water is 1:30, decocting time 4-7 hours; Collecting decoction, filters; Filtrate is concentrated, makes extract;
2) pulverize: new fresh Fructus Crataegi is cleaned and removed seed, dry, then be crushed into 100-300 object particles, obtain powder standby;
3) extract and the powder that mixing: by step 1) and step 2) obtain mix, standby;
4) packing: with plastic film material, vacuum packaging obtains composition product;
5) irradiation: packaged extract is carried out to radiation sterilizing, deposit in shady and cool dry warehouse.
 
The another kind of preparation method of appetizing hypoglycemic composition of the present invention is mixed and made into extract by Niuganguo, Fructus Mori and Fructus Crataegi with the ratio of 1:1:1, then flocculate, spray be dried, packing and irradiation, concrete preparation process is as follows:
1) extract: fresh Niuganguo and Fructus Crataegi are cleaned to enucleation, removed seed, mix with the ratio of 1:1:1 with fresh clean Fructus Mori, break into serosity; After filtration, obtain filtrate for later use;
2) flocculation: filtrate obtained above is added to chitosan clarifier, utilize flocculation, obtain the extract that purity is high;
3) spraying is dry: the extract that step (2) is obtained is sent into the dry powder of making of spraying;
4) packing: with plastic film material, vacuum packaging obtains composition product;
5) irradiation: packaged extract is carried out to radiation sterilizing, deposit in shady and cool dry warehouse.
The prepared appetizing hypoglycemic composition of the present invention, can be prepared into the products such as capsule, the watered pill and electuary, and consumption is: capsule 500mg/ grain, and watered pill 4.5g/ ball, electuary 4.5g adds pure water 10-30ml.
The whet the appetite beneficial effect of hypoglycemic composition of the present invention is:
1, safe and reliable, appetite stimulator.Formula of the present invention is to consist of natural plants, and the Niuganguo in formula, Fructus Mori and Fructus Crataegi are all useful to human body, can long-term taking, can not cause to human body other toxic and side effects.This medicine, in auxiliary reduction patient blood glucose, can also promote patient's appetite simultaneously, strengthens patient's physiological function, supplements several amino acids, vitamin and the protein of needed by human body.
2, instant, good mouthfeel.The present invention can make the products such as the watered pill, capsule and electuary according to different crowd demand, easy to carry, takes simply, is away from home, and only needs one bottle of water, just can easily take.Simultaneously because this combination is made finished product, delicate mouthfeel after adopting modern crafts to extract; And owing to containing Fructus Mori and Fructus Crataegi in prescription, make patient when taking prescription of the present invention, can feel to have pure and fresh and Fructus Crataegi fragrant and sweet of Fructus Mori, be applicable to multiple crowd's taste, while avoiding patient to take, occur feeling sick, detesting sense.
3, diverse in function, nutritious.Take the product that the present invention makes, can not only assist the misery of alleviating hyperglycemic patients, reduce patient for the dependency of the chemical drugss such as antidiabetic drug, alleviate chemical drugs and produce toxic and side effects for the infringement of human body, this compositions also has the strong gas of tonification, blood pressure lowering fat-reducing, slow down aging, the effects such as wetting one's whistle, separate metal and stone poison, blacking hair and beauty, nourishing YIN and invigorating YANG, promoting the production of body fluid to quench thirst and arrhythmia of relieving inflammation or internal heat simultaneously.And this compositions adopts the raw materials such as Niuganguo, Fructus Mori and Fructus Crataegi to make, the nutrition contents such as vitamin C, protein, fat, carotene, starch, malic acid, citric acid, calcium and ferrum are abundant, for strengthening patient's immunity, the syndrome of improving patient has positive effect, and the prevention for diabetes simultaneously also plays a role.
The specific embodiment
Embodiment 1:
Appetizing blood sugar lowering prescription: Niuganguo, Fructus Mori and Fructus Crataegi extract be 2:2:1 in mass ratio.
Preparation method containing said components hypoglycemic composition is as follows:
1) extract: Niuganguo is cleaned after enucleation, added respectively water with clean Fructus Mori, decoct to ripe rotten, the ratio of raw material and water is 1:30, decocting time 4-7 hours; Collecting decoction, filters; Filtrate is concentrated, makes extract;
2) pulverize: new fresh Fructus Crataegi is cleaned and removed seed, dry, then be crushed into 100-300 object particles, obtain powder standby;
3) extract and the powder that mixing: by step 1) and step 2) obtain mix, standby;
4) controlling the water circulation ball: by above-mentioned steps 3) in the mixture of gained, add appropriate water, obtain mixture water cream, mixture water cream is made into watered pill semi-finished product, watered pill semi-finished product are dried and blood and slime ball finished product falls in the appetizing that is made into 4.5 grams/ball.
Embodiment 2
Health care conditioning blood sugar lowering prescription: Niuganguo, Fructus Crataegi and Fructus Mori mix with the ratio of 1:1:1.
Preparation method containing said components hypoglycemic composition is as follows:
1) extract: fresh Niuganguo and Fructus Crataegi are cleaned to enucleation, removed seed, mix with the ratio of 1:1:1 with fresh clean Fructus Mori, break into serosity; After filtration, obtain filtrate for later use;
2) flocculation: filtrate obtained above is added to chitosan clarifier, utilize flocculation, obtain the extract that purity is high;
3) spraying is dry: the extract that step (2) is obtained is sent into the dry powder of making of spraying;
4) glue capsule: the powder that step 3) is obtained is sent into filling machine, is packed into mixed-powder in the sub-capsule of 500mg/ grain, for fear of the leakage of powder in capsule, capsule is sealed, and by quality standard, is up to the standards, and packing becomes formal product.
below the whet the appetite application test of blood pressure reducing composition of the present invention:
One, animal experiment
(1) hyperglycemia Mouse Model is set up
40 white mice that the Shanghai Si Laike Experimental Animal Center of usining is bought are as test material, and every body weight remains on 18-25g.White mice is fed to adaptation after 1 week with standard feed, enter experiment.By mice fasting after 17 hours, to experiment mice lumbar injection 1% alloxan 200mg/kg/d, after continuous 1 week, by mice fasting 5 hours, detect mouse blood sugar value, when mouse blood sugar value is during at 15-30mmol/L, mice is in hyperglycemia, and model is successfully established.
(2) blood sugar test
Choose at random afterwards 20 hyperglycemia white mice and be divided into 2 groups, 10 every group.Each is organized mice and all with standard feed, feeds, and freely drinks water, and adaptability, after 1 week, is recorded fasting blood sugar and correlation circumstance, enters experiment.1 group of white mice fasting is wherein injected to appetizing blood sugar lowering prescription after 6 hours, another group is not injected, and recovers afterwards feeding standard feedstuff, freely drink water, this process repeats 5 days, detects and finds that the white mice blood sugar content of injection appetizing blood sugar lowering prescription obviously declines, and like to move, energetic, hair color light; Greedy the sleeping of white mice of injection appetizing blood sugar lowering prescription, does not take food few, and hair color is matt.
Two, the health-care effect of volunteer application
Application example:
1, Wei, female, 65 years old, suffer from type 2 diabetes mellitus, long-term taking blood sugar lowering chemicals, polyphagia, but body weight become thin, and night polyuria, poor sleeping quality, it is yellow that face is.Through auxiliary the present invention's watered pill that blood sugar lowering prescription makes that whets the appetite of taking, every day 3 times, each 10, after 2 months, body weight is stable, and blood glucose value reduces, and blood sugar lowering dose starts to reduce, and night, polyuria situation was effectively alleviated, and had rosy cheeks, and energy is good.
2, Wang, man, 61 years old, owing to liking ardently, eat meat, and due to old, retirement is in and is sitting in for a long time before television set, lack motion, cause body obesity, malaise, blood glucose is higher.Through taking the present invention's watered pill that blood sugar lowering prescription makes that whets the appetite, every day 2 times, each 10, and adjust diet, and add sharp movement, after 20 days, blood glucose value obviously reduces, and body weight is also recovered normally, energetic.
3, Lee, man, 40 years old, Yi Nanning enterprise was engaged in chief of office's post.Due to job specification reason, need to treat with courtesy for a long time, cause blood sugar increasing, body obesity, drowsiness, evening polyuria.The capsule of making through taking appetizing blood pressure lowering prescription of the present invention, every day 3 times, each 2, and the custom that is careful in one's diet, after one month, it is normal that blood glucose value recovers, weight loss is energetic, evening polyuria situation be improved significantly.
4, Chen, man, 16 years old, student.Because the pressure of entering a higher school is large, extremely have a sweet tooth, and lack effective exercise, cause Chen's blood glucose higher,, easily there is fatigue in body obesity, drowsiness, diet increases the weight of.The capsule of making through taking appetizing blood pressure lowering prescription of the present invention, every day 2 times, each 2, and the custom that is careful in one's diet, after 15 days, blood sugar recovery is normal, and body weight starts to reduce, and feeling of fatigue disappears, full of vitality.

Claims (6)

1. an appetizing hypoglycemic composition, is characterized in that: comprise the extract of Niuganguo, Fructus Mori and Fructus Crataegi, described extract is 2:2:1 in mass ratio.
2. appetizing hypoglycemic composition claimed in claim 1, is characterized in that: comprise the extract of Niuganguo, Fructus Mori and Fructus Crataegi, described extract is 1:1:1 in mass ratio.
3. the preparation method of appetizing hypoglycemic composition claimed in claim 1, comprises extraction, pulverizing, mixing, packing and irradiation, and its concrete preparation process is as follows:
1) extract: Niuganguo is cleaned after enucleation, added respectively water with clean Fructus Mori, decoct to ripe rotten, the ratio of raw material and water is 1:30, decocting time 4-7 hours; Collecting decoction, filters; Filtrate is concentrated, makes extract;
2) pulverize: new fresh Fructus Crataegi is cleaned and removed seed, dry, then be crushed into 100-300 object particles, obtain powder standby;
3) extract and the powder that mixing: by step 1) and step 2) obtain mix, standby;
4) packing: with plastic film material, vacuum packaging obtains composition product;
5) irradiation: packaged extract is carried out to radiation sterilizing, deposit in shady and cool dry warehouse.
4. the preparation method of appetizing hypoglycemic composition claimed in claim 2, comprises that extraction, flocculation, spraying are dry, packing and irradiation, and its concrete preparation process is as follows:
1) extract: fresh Niuganguo and Fructus Crataegi are cleaned to enucleation, removed seed, mix with the ratio of 1:1:1 with fresh clean Fructus Mori, break into serosity; After filtration, obtain filtrate for later use;
2) flocculation: filtrate obtained above is added to chitosan clarifier, utilize flocculation, obtain the extract that purity is high;
3) spraying is dry: the extract that step (2) is obtained is sent into the dry powder of making of spraying;
4) packing: with plastic film material, vacuum packaging obtains composition product;
5) irradiation: packaged extract is carried out to radiation sterilizing, deposit in shady and cool dry warehouse.
5. the preparation method of the appetizing hypoglycemic composition described in claim 1 or 2, the extract of its Niuganguo, Fructus Mori and Fructus Crataegi is all to extract from fresh entity.
6. appetizing hypoglycemic composition according to claim 1 and 2, can be prepared into the products such as capsule, the watered pill and electuary, and consumption is: capsule 500mg/ grain, and watered pill 4.5g/ ball, electuary 4.5g adds pure water 10-30ml.
CN201310505972.1A 2013-10-24 2013-10-24 Composition for appetizing and reducing blood pressure Pending CN103550333A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112168874A (en) * 2019-07-03 2021-01-05 内蒙古伊利实业集团股份有限公司 Action of hawthorn and mulberry on cardiovascular disease
CN112168875A (en) * 2019-07-03 2021-01-05 内蒙古伊利实业集团股份有限公司 Blood sugar reducing effect of combination of hawthorn and mulberry

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1498653A (en) * 2002-11-09 2004-05-26 广西贵港市正宝山泉饮料厂 Extract of 'Sheganguo' and its prepn. method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1498653A (en) * 2002-11-09 2004-05-26 广西贵港市正宝山泉饮料厂 Extract of 'Sheganguo' and its prepn. method

Non-Patent Citations (1)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112168874A (en) * 2019-07-03 2021-01-05 内蒙古伊利实业集团股份有限公司 Action of hawthorn and mulberry on cardiovascular disease
CN112168875A (en) * 2019-07-03 2021-01-05 内蒙古伊利实业集团股份有限公司 Blood sugar reducing effect of combination of hawthorn and mulberry

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Application publication date: 20140205