CN107432463A - A kind of slimming health product and preparation method thereof - Google Patents
A kind of slimming health product and preparation method thereof Download PDFInfo
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of slimming health product, is made up of the raw material of following parts by weight：1~5 part of Ilex Latifolia Thunb, 2~8 parts of sea-buckthorn, 2~7 parts of ginkgo leaf, 2~5 parts of matrimony vine, 1~5 part of hawthorn, 2~6 parts of safflower.The invention also discloses the preparation method of the slimming health product.The product of the present invention has Weight-reducing health effect, can be supplied to the crowds such as essential hypertension, obesity long-term use.
Description
Technical field
The invention belongs to field of health care products, is a kind of slimming health product and preparation method thereof.
Background technology
Obesity is the excessive caused phenomenon of body fat mass in human body accumulation, and obesity not only influences pretty figure, and is made troubles to life, more importantly easily causes multiple complications, accelerates aging and death.The incidence of disease of the concurrent cerebral embolism of overweight people and heart failure doubles than regular severe one according to statistics, suffer from coronary heart disease 2 times more than regular severe one, Hypertension incidence is 2~6 times more than regular severe one, complication with diabetes person about increases 4 times compared with normal person, merge cholelithiasis person it is high compared with normal person 4~6 times, more seriously the life-span of overweight people will substantially shorten.Overweight people's adipose tissue increases, and oxygen demand increases, and heart amount of work is big, makes myocardial hypertrophy, especially left ventricle burden, long easy induction hypertension.Lipidosis causes luminal stenosis in arterial wall, hardening, coronary heart diseases and angina pectoris, apoplexy and sudden death easily occurs.Because the hyperinsulinemia of overweight people makes the synthesis of its endogenous triglycerides hyperfunction, it will result in the triglycerides synthesized in liver and accumulate so as to form fatty liver.Compared with normal person, the cholesterol level in bile acid increases overweight people, has exceeded the solubility in bile, therefore the easy concurrent a high proportion of cholesterol stone of overweight people, has had been reported that the women 50~80% for suffering from cholelithiasis is overweight people.It is fat to be classified as one of 5 big diseases for seriously endangering human health by the World Health Organization.
Relevant ways of preventing obesity mainly has Orally taken product, operative treatment etc. both at home and abroad at present.Lipposuction has wound, the postoperative possibility for also having bounce-back.Oral diet products are broadly divided into appetite inhibitor, eccritic, promote metabolism class and block fat absorption class.The main slimming ingredient of medicine of losing weight is sibutramine hydrochloride, because it may cause the serious side effects of harm such as apoplexy, blood pressure rise, increased heart rate, apocleisis, insomnia, dysfunction of liver, national Bureau of Drugs Supervision has announced that stopping production and sales using sibutramine preparation and bulk drug.There are some in addition using the diet products that there is wash with watercolours to let out effect for also having detrimental effect to health.
The content of the invention
The purpose of the present invention is that the defects of overcoming above-mentioned prior art, there is provided a kind of slimming health product, has significant fat-reducing effect.
Technical scheme：A kind of slimming health product, it is made up of the raw material of following parts by weight
1~6 part of Ilex Latifolia Thunb
2~8 parts of sea-buckthorn
2~7 parts of ginkgo leaf
2~5 parts of matrimony vine
1~5 part of hawthorn
2~6 parts of safflower
Preferably, the parts by weight of the Ilex Latifolia Thunb are 3 parts.
Preferably, the parts by weight of the sea-buckthorn are 6 parts.
Preferably, the parts by weight of the ginkgo leaf are 5 parts.
Preferably, the parts by weight of the matrimony vine are 2 parts.
Preferably, the parts by weight of the hawthorn are 3 parts.
Preferably, the parts by weight of the safflower are 4 parts.
The health products are oral agents
The present invention is using the Ilex Latifolia Thunb with hypoglycemic, sea-buckthorn, ginkgo leaf, matrimony vine, hawthorn, the pure plants such as safflower, utilize the active ingredient contained by them, the activity of body metabolism enzyme can be adjusted, strengthen the fatty decomposition in norepinephrine inducing adipocyte, promote the activity of hormone-sensitive lipase, the oxidation Decomposition of body fat tissue can be accelerated, curative effect on obesity is good, persistent is stable, have no adverse reaction, and Ilex Latifolia Thunb, sea-buckthorn, hawthorn, matrimony vine or preferable health food, the long-term use of health beneficial to human body, it is a kind of ideal diet food.
The composition of Chinese medicine compound prescription of the present invention is according to being：Containing Multiple components such as bitter leaves saponin(e, amino acid, vitamin C, flavonoids in Ilex Latifolia Thunb, there are the multiple efficacies such as lowering blood pressure and blood fat, fat-reducing, be its prescription main component；
The compositions such as the general flavone that contains in sea-buckthorn, aliphatic acid can soften blood vessel, stimulate circulation, reduce blood viscosity, reduce blood glucose, blood fat also efficiency regulation blood pressure, prevent human body artery from hardening.Containing nutritions such as abundant amino acid, machine acid in sea-buckthorn, think that sea-buckthorn has the effect of preventing phlegm from forming and stopping coughing, stomach strengthening and digestion promoting in the traditional Chinese medical science.
Ginkgo leaf has dissolving cholesterol, expands the effect of blood vessel, improves the effect of brain disorder, artery sclerosis, hypertension；
Matrimony vine have the function that it is nourishing liver and kidney, nourish the liver to improve visual acuity, can with lowering blood pressure and blood fat, improve immune function of human body.
Hawthorn has that disperse accumulationsization is stagnant, astriction, can promote the digestion of fat food；
Safflower has regulation human endocrine, accelerates human metabolism, excludes vivotoxin, and a good environment is created for neoblast regeneration；Cucumber Extract simultaneously, skin vigour is supplemented, improve skin horn cell water storage, the ability of water lock, lift horn cell water content；
Slimming health product of the present invention is tested through studies on acute toxicity and proved, without any side effects.
The application method and dosage of slimming health product of the present invention：The dose of the present invention depends on the factors such as specific formulation, the age of patient, health status.As guidance：As Orally taken product, recommendation dosage is 10g~20g/day, is once taken before sleeping every night.
Present invention also offers a kind of preparation method of slimming health product, comprise the following steps：
1., by following weight parts weigh each raw material：
1~6 part of Ilex Latifolia Thunb
2~8 parts of sea-buckthorn
2~7 parts of ginkgo leaf
2~5 parts of matrimony vine
1~5 part of hawthorn
2~6 parts of safflower
2., each raw material mixed, add the extraction of 50%~80% alcohol reflux；Filtering, concentrates filtrate to thick paste, produces slimming health product.
Preferably, the preparation method is further comprising the steps of：
3., thick paste dried, add the auxiliary material or excipients needed for oral agents shaping, finished product be made.
Preferably, 2. middle reflux extracting time is 3 hours to step；The relative density of thick paste is 1.24~1.27.
Compared with prior art, the present invention carries out the mixture of each raw material composition of refluxing extraction using ethanol, filtrate is condensed into thick paste after filtering, you can obtain slimming health product.The auxiliary material or excipient needed for preparations shaping can be wherein added into thick paste, various oral agents, such as tablet, granule, capsule, mixture, pill, oral liquid, syrup or pill are made.Whole manufacture craft is simple and easy, easy to operate, is suitable for the production and processing of middle-size and small-size or integrated mill.
Embodiment
The preparation of the granule of embodiment 1
Ilex Latifolia Thunb 300g, sea-buckthorn 600g, ginkgo leaf 500g, matrimony vine 200g, hawthorn 300g, safflower 400g are taken, above-mentioned raw materials are mixed；Add 20 liters of 70wt% ethanol and carry out refluxing extraction 3 times, each 60min.Filtering, it is 1.25 (70 DEG C) to concentrate filtrate to relative density, spray drying；The auxiliary materials such as appropriate starch, fructose sugar are added, pelletizes, produces.
The preparation of the capsule of embodiment 2
Ilex Latifolia Thunb 300g, sea-buckthorn 600g, ginkgo leaf 500g, matrimony vine 200g, hawthorn 300g, safflower 400g are taken, above-mentioned raw materials are mixed；Add 20 liters of 70wt% ethanol and carry out refluxing extraction 3 times, each 60min.Filtering, relative density is concentrated filtrate to as 1.26（70℃）, spray drying；Appropriate capsule auxiliary material is added, is mixed, granulation, loads No. 2 Capsuleses, produces.
The preparation of the tablet of embodiment 3
Ilex Latifolia Thunb 300g, sea-buckthorn 600g, ginkgo leaf 500g, matrimony vine 200g, hawthorn 300g, safflower 400g are taken, above-mentioned raw materials are mixed；Add 20 liters of 70wt% ethanol and carry out refluxing extraction 3 times, each 60min.Filtering, relative density is concentrated filtrate to as 1.25（70℃）, spray drying；The auxiliary materials such as appropriate amylum pregelatinisatum, fructose are added, are mixed, granulation, tabletting, are produced.
The preparation of the pill of embodiment 4
Ilex Latifolia Thunb 300g, sea-buckthorn 600g, ginkgo leaf 500g, matrimony vine 200g, hawthorn 300g, safflower 400g are taken, above-mentioned raw materials are mixed；Add 20 liters of 70wt% ethanol and carry out refluxing extraction 3 times, each 60min.Filtering, relative density is concentrated filtrate to as 1.25（70℃）, spray drying；The auxiliary materials such as appropriate starch are added, pill, are produced.
The preparation of the syrup of embodiment 5
Ilex Latifolia Thunb 300g, sea-buckthorn 600g, ginkgo leaf 500g, matrimony vine 200g, hawthorn 300g, safflower 400g are taken, above-mentioned raw materials are mixed；Add 20 liters of 70wt% ethanol and carry out refluxing extraction 3 times, each 60min.Filtering, relative density is concentrated filtrate to as 1.26（70℃）；The auxiliary materials such as appropriate sucrose, tartaric acid, sodium benzoate, purified water are added, it is filling, produce.
Clinical test
300 obese patients are randomly divided into six groups, it is average every group 50, set up control group and four treatment groups separately, treatment group is taking in the morning and evening preparation made from above-described embodiment 1 to embodiment 5 respectively unlike control group.
1st, it is Simple Obesity Patient in clinical data 300, the course of disease is most short 1 year, most long 30 years.Mild Obesity 80, central obesity 160, severe simple obesity 60.
1 clinical general information of table
2nd, diagnosis and criterion of therapeutical effect
2.1st, diagnostic criteria foundation《Practical clinical practice》Regulation, the body weight that is above standard 20% [standard weight=（Height -100）Cm × 0.9] or body mass index be more than 24.
2.2nd, fat division and criterion of therapeutical effect refer to national combination of Chinese tradiational and Western medicine obesity in 1987
The simple obesity curative effect judging standard that research academic exchange can determine whether.
Mild Obesity is above standard body weight 20~30%
Central obesity is above standard body weight 30~50%
Severe simple obesity is above standard body weight more than 50%
Effective Body weight loss >=10kg, waistline reduction >=10cm
Effective Body weight loss >=3kg, waistline reduction >=4cm
Invalid Body weight loss ＜ 3kg, waistline reduce ＜ 4cm
2.3rd, treatment method
Treatment group takes in the morning and evening compound Ilex Kudingcha diet food daily, every time equivalent to the particular/special requirements of crude drug amount 15g, diet, motion etc. five.Fat-reducing effect is counted after two months, the results are shown in Table 2
The clinical each group fat-reducing effect statistical form of table 2
| Group | Number | It is effective | Effectively | It is invalid | It is efficient（%） |
| Embodiment 1 | 50 | 10 | 36 | 4 | 92 |
| Embodiment 2 | 50 | 8 | 37 | 5 | 90 |
| Embodiment 3 | 50 | 5 | 40 | 5 | 90 |
| Embodiment 4 | 50 | 7 | 35 | 8 | 84 |
| Embodiment 5 | 50 | 9 | 38 | 3 | 94 |
| Control group | 50 | 0 | 0 | 0 | 0 |
As can be seen from Table 2, the treatment group of each embodiment is at least 84% on fat-reducing effect apparently higher than control group, total effective rate.Illustrating the slimming health product of the present invention has obviously fat-reducing effect.
Claims (11)
1. a kind of slimming health product, it is made up of the raw material of following parts by weight：
1~6 part of Ilex Latifolia Thunb
2~8 parts of sea-buckthorn
2~7 parts of ginkgo leaf
2~5 parts of matrimony vine
1~5 part of hawthorn
2~6 parts of safflower.
2. the slimming health product as described in claim 1, it is characterised in that：The parts by weight of the Ilex Latifolia Thunb are 3 parts.
3. the slimming health product as described in claim 1, it is characterised in that：The parts by weight of the sea-buckthorn are 6 parts.
4. the slimming health product as described in claim 1, it is characterised in that：The parts by weight of the ginkgo leaf are 5 parts.
5. the slimming health product as described in claim 1, it is characterised in that：The parts by weight of the matrimony vine are 2 parts.
6. the slimming health product as described in claim 1, it is characterised in that：The parts by weight of the hawthorn are 3 parts.
7. the slimming health product as described in claim 1, it is characterised in that：The parts by weight of the safflower are 4 parts.
8. the slimming health product as described in claim 1, it is characterised in that：The health products are oral agents.
9. a kind of preparation method of slimming health product, comprises the following steps：
1., by following weight parts weigh each raw material：
1~6 part of Ilex Latifolia Thunb
2~8 parts of sea-buckthorn
2~7 parts of ginkgo leaf
2~5 parts of matrimony vine
1~5 part of hawthorn
2~6 parts of safflower
2., each raw material mixed, add the extraction of 50%~80% alcohol reflux；Filtering, concentrates filtrate to thick paste, produces slimming health product.
10. preparation method as claimed in claim 9, it is characterised in that：The preparation method is further comprising the steps of：
Thick paste is dried, auxiliary material or excipients needed for oral agents shaping is added, finished product is made.
11. the preparation method as described in claim 9 or 10, it is characterised in that：2. middle reflux extracting time is 3 hours to step；The relative density of thick paste is 1.24~1.27.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102132870A (en) * | 2011-02-25 | 2011-07-27 | 中国热带农业科学院热带生物技术研究所 | Diet health-care product and preparation method thereof |
| CN102430022A (en) * | 2011-12-30 | 2012-05-02 | 苏州爱斯欧蒂生物科技有限公司 | Weight-reducing health-care product and preparation method thereof |
| CN104055855A (en) * | 2013-03-22 | 2014-09-24 | 黄建强 | Dietotherapy composition for losing weight |
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| CN102132870A (en) * | 2011-02-25 | 2011-07-27 | 中国热带农业科学院热带生物技术研究所 | Diet health-care product and preparation method thereof |
| CN102430022A (en) * | 2011-12-30 | 2012-05-02 | 苏州爱斯欧蒂生物科技有限公司 | Weight-reducing health-care product and preparation method thereof |
| CN104055855A (en) * | 2013-03-22 | 2014-09-24 | 黄建强 | Dietotherapy composition for losing weight |
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Application publication date: 20171205 |