CN108635426A - A kind of Colestid traditional Chinese drug inspissation water-bindered pill and preparation process - Google Patents
A kind of Colestid traditional Chinese drug inspissation water-bindered pill and preparation process Download PDFInfo
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Abstract
The invention discloses a kind of Colestid traditional Chinese drug inspissation water-bindered pill and preparation processes, and in particular to technical field of traditional Chinese medicines, the Colestid traditional Chinese drug inspissation water-bindered pill of the present invention includes component:Hawthorn (stoning), prepared fleece flower root, cassia seed, lotus leaf, sucrose;Hawthorn, cassia seed are decocted into secondary, boil liquid, filter the dregs of a decoction, filtrate is concentrated into clear cream;Lotus leaf, prepared fleece flower root refluxing extraction are concentrated under reduced pressure into clear cream, and clear cream merges, and adds dextrin appropriate, and mixing obtains and always extracts medicinal extract, dry, obtains dry extract;By dry extract obtained above, the general pelletization of water, packing;The water-bindered pill of the present invention is tasteless to lightly seasoned, micro- taste of traditional Chinese medicine, the water-bindered pill has that small, surface compact is smooth, convenient for swallowing, be not easy the moisture absorption, cover adverse drug smell, the advantages that production equipment is simple, it is carried convenient for patient and stores and take, and reduce cholesterol, accelerate cholesterol excretion, the effects that inhibition serum cholesterol increases and atherosclerotic plaque is formed, reducing blood lipid and cholesterol.
Description
Technical field:
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of Colestid traditional Chinese drug inspissation water-bindered pill and preparation process.
Background technology:
Hyperlipidemia is primarily referred to as serum total cholesterol (TC) or the horizontal excessively high and (or) serum of triglycerides (TG) is highly dense
It is horizontal too low to spend lipoproteins-C (HDL-C).Hyperlipidemia is the common disease and frequently-occurring disease of person in middle and old age, as people live
The change of horizontal raising and living habit, the incidence of the disease obviously increase, and the age of morbidity is also shifted to an earlier date.Hyperlipidemia
Caused atherosclerosis is the main reason for causing coronary heart disease, hypertension and cranial vascular disease, the whole world every year there are about
12000000 people die of cardiovascular disease and headstroke.So the treatment of hyperlipidemia is extremely important, this has caused the height of the whole mankind
Concern.
The final purpose for the treatment of hyperlipidemia is to inhibit the further development of artery sclerosis, to prevent by cardiovascular and cerebrovascular etc.
It is dead caused by disease.Western medicine currently used for treatment hyperlipidemia is due to its is rapid-action and curative effect affirmative by everybody blueness
It looks at, but Western medicine has different degrees of toxic side effect, research to find that Statins drug can cause patient blood glucose abnormal, show as
Fasting blood glucose level raising, glycated hemoglobin levels raising, New-Onset Diabetes Mellitus, diabetes glucose control deterioration etc..In addition, he
Spit of fland similar drug is taken simultaneously with hiv protease inhibitor, and the blood concentration of statins may be made to increase, and increase includes horizontal
The occurrence risk of serious adverse reaction including line myolysis.
Currently there are the drugs of various reducing blood lipid, but contain toxin in most drugs, and
Side effect is more, and Chinese medicine prevents cardiovascular and cerebrovascular disease generation etc. from having unique advantage in treatment hyperlipidemia, treats
Effect affirmative, continues, Small side effects, is that Western medicine institute is incomparable.Especially in terms of differentiation of symptoms and signs for classification of syndrome, flexible group of Chinese medicine is embodied
Side, the therapeutic features suited measures to different persons.
Chinese kmedicine bolus (starched pill) is now by wide clinical application, they have, and small, surface compact is smooth, is convenient for
It swallows, be not easy the moisture absorption, adverse drug smell can be covered, the advantages that production equipment is simple.
In CN201610061127.3, a kind of sugar-free JIANGZHINING KELI and preparation method thereof, a kind of nothing of the disclosure of the invention are disclosed
Sugared JIANGZHINING KELI, the Chinese medicine are prepared by the raw material of following parts by weight:20-25.5 portions of hawthorn, 1-1.25 parts of prepared fleece flower roots,
1-1.25 parts of cassia seeds, 3.25-3.55 parts of lotus leaves.JIANGZHINING KELI produced by the present invention has expansion coronary artery blood vessel, increases hat
Arteries and veins flow reduces cholesterol absorption, accelerates cholesterol excretion, inhibits serum cholesterol raising and atherosclerotic plaque shape
At the effects that reducing blood lipid and cholesterol.The present invention is more suitable for middle and elderly diabetic patient use, expands drug without sucrose
Use scope.
It is long-term to carry drug not side because lipid-loweringing patient needs prolonged administration of drugs but in existing technical field
Just, and drug is easy to make moist, it is therefore desirable to carry out moisture preventive measure to drug, be followed successively by life and bring life many inconvenient.
Invention content:
The present invention develops a kind of Colestid traditional Chinese drug inspissation water-bindered pill, both can effectively reduce blood fat, can give absorption of human body rapidly,
To reducing blood lipid, soften blood vessel, enhancing coronary flow cycle, arrhythmia and hyperlipemia have good therapeutic effect;And water
Ball has that small, surface compact is smooth, convenient for swallowing, being not easy the moisture absorption, can cover adverse drug smell, and production equipment is simple etc.
Advantage.
The invention solves above-mentioned technical problem be to provide the Colestid traditional Chinese drug inspissation water-bindered pill and preparation process.
In order to solve the above technical problems, the present invention uses following technical proposals:
The Colestid traditional Chinese drug inspissation water-bindered pill includes following component raw material:
Title | Number |
Hawthorn (stoning) | 400-500 |
Prepared fleece flower root | 25-35 |
Cassia seed | 25-40 |
Lotus leaf | 75-90 |
Sucrose | 100-200 |
Ethyl alcohol | 50-100 (preparation use) |
400-500 parts of hawthorn (stoning), 25-35 parts of prepared fleece flower root, 25-40 parts of cassia seed, 75-90 parts of lotus leaf, sucrose
100-200 parts, adds 4 times of amount pure water to decoct hawthorn, cassia seed secondary, 2 hours every time, merge decoction liquor, filter the dregs of a decoction, filter
Liquid carries out being concentrated under reduced pressure into the clear cream that relative density is 1.26-1.32 (50 DEG C);2 times of remaining lotus leaf, prepared fleece flower root dilute second of amount
Alcohol reflux extracts three times, 3 hours for the first time, second 2 hours, and third time 1 hour merges extracting solution, recycles ethyl alcohol, and decompression is dense
It is reduced to the clear cream of relative density 1.25-1.35 (50 DEG C), is merged with above-mentioned thick paste, adds dextrin appropriate, mixing obtains always extraction leaching
Cream, it is dry, obtain dry extract;By dry extract obtained above, the general pelletization of water, packing to get.
Chinese medicine hawthorn contained by the Colestid water-bindered pill is containing crataegolic acid, flavone of hawthorn fruit.Coronary artery blood vessel can be expanded, coronary flow is increased;
The permeability for increasing heart capillaries and cardiac muscle fibre increases the nutrient flow amount of cardiac muscle;The fleece-flower root contains Rhein, big
Flavine, the anthraquinones such as Chrysophanol, aloe-emodin can promote intestines peristalsis, reduce cholesterol absorption, accelerate cholesterol row
It lets out, to play the role of reducing blood fat, antiatherosclerosis;Cassia seed mainly contains phytosterol and anthraquinones,
Have the function of that serum cholesterol is inhibited to increase and atherosclerotic plaque formation;Lotus leaf contains Nuciferine, has solution to smooth muscle
Convulsion acts on.The water-bindered pill of the present invention contains sucrose, is more suitable for not liking the crowd of Chinese medicine bitter taste.
Wherein above-mentioned each ingredient filters the dregs of a decoction, strainer 80-100 mesh screens after decocting.
Concentration condition is temperature (50-60 DEG C), vacuum degree -0.07~-0.08MPa after each ingredient decocts in being wherein formulated.
Wherein above-mentioned recycling ethyl alcohol condition is steam pressure:0.2-0.4mpa, vapor (steam) temperature:100-120℃.
Wherein above-mentioned reduced pressure condition is 50-60 DEG C of temperature, vacuum degree -0.07~-0.08MPa.
Yellowish-brown of the present invention to sepia the water-bindered pill;The water-bindered pill is tasteless to lightly seasoned, micro- taste of traditional Chinese medicine.With reducing blood lipid, soften blood
Pipe acts on.For enhancing coronary flow cycle, arrhythmia and hyperlipemia have obvious curative effects.Such form of Chinese drug
Feature can be absorbed by the body rapidly, markedly fast.
(1) the Colestid water-bindered pill produced by the present invention has expansion coronary artery blood vessel, increases coronary flow, reduces cholesterol and inhales
It receives, accelerates cholesterol excretion, inhibit serum cholesterol to increase and atherosclerotic plaque is formed, the works such as reducing blood lipid and cholesterol
With.
(2) the Colestid water-bindered pill produced by the present invention contains sucrose, is more suitable for not liking the crowd of Chinese medicine bitter taste, expand
The use scope of drug.
(3) water-bindered pill is tasteless to lightly seasoned, micro- taste of traditional Chinese medicine, and the water-bindered pill has that small, surface compact is smooth, convenient for swallowing, be not easy
The advantages that moisture absorption can cover adverse drug smell, and production equipment is simple, the patient that is more convenient for carry and store and take.
Figure of description:
Fig. 1 is Colestid medicinal extract processing technological flow figure;
Fig. 2 is Colestid water-bindered pill process flow chart.
Specific implementation mode:
In order to make the technical means, the creative features, the aims and the efficiencies achieved by the present invention be easy to understand, tie below
Specific embodiment is closed, the present invention is further explained.
The scheme of embodiment of the present invention, does not limit the present invention, one of skill in the art with reference to the present invention spirit,
It can make improvements and change, the such modifications and variations are regarded as within the scope of the invention, of the invention
Scope and spirit are defined by the claims.
Embodiment 1:
The Colestid traditional Chinese drug inspissation water-bindered pill includes following component raw material:
Title | Number |
Hawthorn (stoning) | 450 |
Prepared fleece flower root | 35 |
Cassia seed | 25 |
Lotus leaf | 75 |
Sucrose | 100 |
Ethyl alcohol | 60 |
450 parts of hawthorn (stoning), 35 parts of prepared fleece flower root, 25 parts of cassia seed, 75 parts of lotus leaf, 100 parts of sucrose, by hawthorn, certainly
It is secondary that pine torch adds 4 times of amount pure water to decoct, and 2 hours every time, merges decoction liquor, filters the dregs of a decoction, filtrate carries out being concentrated under reduced pressure into phase
To the clear cream that density is 1.26-1.32 (50 DEG C);Remaining lotus leaf, prepared fleece flower root measure Diluted Alcohol refluxing extractions three times with 2 times, and first
Secondary 3 hours, second 2 hours, third time 1 hour merged extracting solution, recycles ethyl alcohol, is concentrated under reduced pressure into relative density 1.25-
The clear cream of 1.35 (50 DEG C), merges with above-mentioned thick paste, adds dextrin appropriate, and mixing obtains and always extracts medicinal extract, dry, obtains dry extract;
By dry extract obtained above, the general pelletization of water, packing to get.
Wherein above-mentioned each ingredient filters the dregs of a decoction, 80 mesh screens of the strainer after decocting.
Concentration condition is 50-55 DEG C of temperature, vacuum degree -0.07MPa after each ingredient decocts in being wherein formulated.
Wherein above-mentioned recycling ethyl alcohol condition is steam pressure:0.25mpa, vapor (steam) temperature:100℃.
Wherein above-mentioned reduced pressure condition is 50-55 DEG C of temperature, vacuum degree -0.07MPa.
Embodiment 2:
The Colestid traditional Chinese drug inspissation water-bindered pill includes following component raw material:
Title | Number |
Hawthorn (stoning) | 400 |
Prepared fleece flower root | 30 |
Cassia seed | 35 |
Lotus leaf | 80 |
Sucrose | 120 |
Ethyl alcohol | 75 |
400 parts of hawthorn (stoning), 30 parts of prepared fleece flower root, 35 parts of cassia seed, 80 parts of lotus leaf, 120 parts of sucrose, by hawthorn, certainly
It is secondary that pine torch adds 4 times of amount pure water to decoct, and 2 hours every time, merges decoction liquor, filters the dregs of a decoction, filtrate carries out being concentrated under reduced pressure into phase
To the clear cream that density is 1.26-1.32 (50 DEG C);Remaining lotus leaf, prepared fleece flower root measure Diluted Alcohol refluxing extractions three times with 2 times, and first
Secondary 3 hours, second 2 hours, third time 1 hour merged extracting solution, recycles ethyl alcohol, is concentrated under reduced pressure into relative density 1.25-
The clear cream of 1.35 (50 DEG C), merges with above-mentioned thick paste, adds dextrin appropriate, and mixing obtains and always extracts medicinal extract, dry, obtains dry extract;
By dry extract obtained above, the general pelletization of water, packing to get.
Wherein above-mentioned each ingredient filters the dregs of a decoction, 100 mesh screens of the strainer after decocting.
Concentration condition is 55-60 DEG C of temperature, vacuum degree -0.08MPa after each ingredient decocts in being wherein formulated.
Wherein above-mentioned recycling ethyl alcohol condition is steam pressure:0.3mpa, vapor (steam) temperature:100℃.
Wherein above-mentioned reduced pressure condition is 55-60 DEG C of temperature, vacuum degree -0.08MPa.
Yellowish-brown of the present invention to sepia the water-bindered pill;The water-bindered pill is tasteless to lightly seasoned, micro- taste of traditional Chinese medicine.With reducing blood lipid, soften blood
Pipe acts on.For enhancing coronary flow cycle, arrhythmia and hyperlipemia have obvious curative effects.Such form of Chinese drug
Feature can be absorbed by the body rapidly, markedly fast.
Embodiment 3:
The Colestid traditional Chinese drug inspissation water-bindered pill includes following component raw material:
Title | Number |
Hawthorn (stoning) | 480 |
Prepared fleece flower root | 35 |
Cassia seed | 30 |
Lotus leaf | 85 |
Sucrose | 150 |
Ethyl alcohol | 65 |
480 parts of hawthorn (stoning), 35 parts of prepared fleece flower root, 30 parts of cassia seed, 85 parts of lotus leaf, 150 parts of sucrose, by hawthorn, certainly
It is secondary that pine torch adds 4 times of amount pure water to decoct, and 2 hours every time, merges decoction liquor, filters the dregs of a decoction, filtrate carries out being concentrated under reduced pressure into phase
To the clear cream that density is 1.26-1.32 (50 DEG C);Remaining lotus leaf, prepared fleece flower root measure Diluted Alcohol refluxing extractions three times with 2 times, and first
Secondary 3 hours, second 2 hours, third time 1 hour merged extracting solution, recycles ethyl alcohol, is concentrated under reduced pressure into relative density 1.25-
The clear cream of 1.35 (50 DEG C), merges with above-mentioned thick paste, adds dextrin appropriate, and mixing obtains and always extracts medicinal extract, dry, obtains dry extract;
By dry extract obtained above, the general pelletization of water, packing to get.
Wherein above-mentioned each ingredient filters the dregs of a decoction, 90 mesh screens of the strainer after decocting.
Concentration condition is temperature 60 C, vacuum degree -0.08MPa after each ingredient decocts in being wherein formulated.
Wherein above-mentioned recycling ethyl alcohol condition is steam pressure:0.25mpa, vapor (steam) temperature:120℃.
Wherein above-mentioned reduced pressure condition is temperature 60 C, vacuum degree -0.08MPa.
Yellowish-brown of the present invention to sepia the water-bindered pill;The water-bindered pill is tasteless to lightly seasoned, micro- taste of traditional Chinese medicine.With reducing blood lipid, soften blood
Pipe acts on.For enhancing coronary flow cycle, arrhythmia and hyperlipemia have obvious curative effects.Such form of Chinese drug
Feature can be absorbed by the body rapidly, markedly fast.
Reference examples 1:
The Colestid traditional Chinese drug inspissation water-bindered pill includes following component raw material:
Title | Number |
Hawthorn (stoning) | 400 |
The fleece-flower root | 35 |
Ethyl alcohol | 50 |
400 parts of hawthorn (stoning), 35 parts of prepared fleece flower root is secondary by hawthorn plus 4 times of amount pure water decoctions, 2 hours every time, closes
And decoction liquor, the dregs of a decoction are filtered, filtrate carries out being concentrated under reduced pressure into the clear cream that relative density is 1.26-1.32 (50 DEG C);It is first what it makes
Three times with 2 times of amount Diluted Alcohol refluxing extractions, 3 hours for the first time, second 2 hours, third time 1 hour merged extracting solution to crow, returns
Ethyl alcohol is received, the clear cream of relative density 1.25-1.35 (50 DEG C) is concentrated under reduced pressure into, merges with above-mentioned thick paste, add dextrin appropriate, is mixed
It is even, it obtains and always extracts medicinal extract, it is dry, obtain dry extract;By dry extract obtained above, the general pelletization of water, packing to get.
Wherein above-mentioned each ingredient filters the dregs of a decoction, 80 mesh screens of the strainer after decocting.
Concentration condition is 55 DEG C of temperature, vacuum degree -0.07MPa after each ingredient decocts in being wherein formulated.
Wherein above-mentioned recycling ethyl alcohol condition is steam pressure:0.25mpa, vapor (steam) temperature:120℃.
Wherein above-mentioned reduced pressure condition is 55 DEG C of temperature, vacuum degree -0.07MPa.
Yellowish-brown of the present invention to sepia the water-bindered pill;The water-bindered pill is tasteless to lightly seasoned, micro- taste of traditional Chinese medicine.
Reference examples 2:
The Colestid traditional Chinese drug inspissation water-bindered pill includes following component raw material:
Title | Number |
Hawthorn (stoning) | 500 |
Lotus leaf | 90 |
Ethyl alcohol | 50-100 (preparation use) |
400-500 parts of hawthorn (stoning), 90 parts of lotus leaf is secondary by hawthorn plus 4 times of amount pure water decoctions, 2 hours every time, closes
And decoction liquor, the dregs of a decoction are filtered, filtrate carries out being concentrated under reduced pressure into the clear cream that relative density is 1.26-1.32 (50 DEG C);Remaining lotus leaf
Three times with 2 times of amount Diluted Alcohol refluxing extractions, 3 hours for the first time, second 2 hours, third time 1 hour merged extracting solution, recycling
Ethyl alcohol is concentrated under reduced pressure into the clear cream of relative density 1.25-1.35 (50 DEG C), merges with above-mentioned thick paste, adds dextrin appropriate, mixing,
It obtains and always extracts medicinal extract, it is dry, obtain dry extract;By dry extract obtained above, the general pelletization of water, packing to get.
Wherein above-mentioned each ingredient filters the dregs of a decoction, 100 mesh screens of the strainer after decocting.
Concentration condition is temperature 60 C, vacuum degree -0.08MPa after each ingredient decocts in being wherein formulated.
Wherein above-mentioned recycling ethyl alcohol condition is steam pressure:0.4mpa, vapor (steam) temperature:-120℃.
Wherein above-mentioned reduced pressure condition is temperature 60 C, vacuum degree -0.08MPa.
Yellowish-brown of the present invention to sepia the water-bindered pill;The water-bindered pill is tasteless to lightly seasoned, micro- taste of traditional Chinese medicine.
It takes and is used for clinical treatment by the Colestid water-bindered pill made from embodiment method and reference examples method.
250 hyperlipemias are randomly divided into 5 groups, every group 50,40 male, female 10;35~70 years old age;Disease
Cheng Siyue~9 year.Control group 50, man 35, female 15;35 years old~70 years old age;The course of disease 4 months~8 years.Diagnostic criteria:Ginseng
According to documentation standards.
Treatment group:Give the Colestid water-bindered pill, usage and dosage:Boiling water is taken after mixing it with water, and three times per day, once a bag, 30 days are a treatment
Journey.Control group:It takes once a bag, 30 days as a treatment course count curative effect after two months.
It can be seen from Table 1 that two groups of pretherapy and post-treatment Blood Lipids, reference literature standard rating curative effect.General adult
Total cholesterol is no more than 5.72mmol/L in Diagnostic Value of Fasting Serum, and triglycerides is no more than 1.70mmol/L, and high-density lipoprotein is normal
Range:0.7--2.0mmol/L;Low-density lipoprotein normal range (NR):0~3.1mmol/L
1 embodiment group of table and the pretherapy and post-treatment Blood Lipid of reference examples group (x ± s, mmol/L)
2 embodiment group of table and reference examples group treatment curative effect statistics (every group of 50 term and general principles)
Group | It is effective | Effectively | In vain | Total effective rate |
Embodiment 1 | 28 | 18 | 4 | 90% |
Embodiment 2 | 35 | 12 | 3 | 94% |
Embodiment 3 | 32 | 15 | 3 | 94% |
Reference examples 1 | 0 | 1 | 49 | 2% |
Reference examples 2 | 0 | 2 | 48 | 4% |
It is wherein above-mentioned effective:No longer there is dizziness, spiritlessness and weakness, insomnia forgetfulness, extremity numbness, uncomfortable in chest, palpitaition etc. in patient,
And blood testing index is in normal range (NR);
Effectively:There is dizziness, spiritlessness and weakness, insomnia forgetfulness, extremity numbness, uncomfortable in chest, palpitaition etc. once in a while in patient, and blood is examined
It surveys in index normal range (NR);
In vain:Patient still has dizziness, spiritlessness and weakness, insomnia forgetfulness, extremity numbness, uncomfortable in chest, palpitaition etc. once in a while, and blood is examined
Index is surveyed not in normal range (NR).
The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention.The technology of the industry
Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the above embodiments and description only describe this
The principle of invention, without departing from the spirit and scope of the present invention, various changes and improvements may be made to the invention, these changes
Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and its
Equivalent thereof.
Claims (6)
1. a kind of Colestid traditional Chinese drug inspissation water-bindered pill, which is characterized in that the Colestid traditional Chinese drug inspissation water-bindered pill includes following component
Raw material:
2. the preparation process of the Colestid traditional Chinese drug inspissation water-bindered pill according to claim 1, which is characterized in that as follows into
Row:
400-500 parts of hawthorn (stoning), 25-35 parts of prepared fleece flower root, 25-40 parts of cassia seed, 75-90 parts of lotus leaf, sucrose 100-200
Part, add 4 times of amount pure water to decoct hawthorn, cassia seed secondary, 2 hours every time, merges decoction liquor, filter the dregs of a decoction, filtrate carries out
It is concentrated under reduced pressure into the clear cream that relative density is 1.26-1.32 (50 DEG C);2 times of remaining lotus leaf, prepared fleece flower root amount Diluted Alcohol reflux
Three times, 3 hours for the first time, second 2 hours, third time 1 hour merged extracting solution, recycles ethyl alcohol, is concentrated under reduced pressure into phase for extraction
To the clear cream of density 1.25-1.35 (50 DEG C), merging with above-mentioned thick paste, adds dextrin appropriate, mixing obtains and always extracts medicinal extract, dry,
Obtain dry extract;By dry extract obtained above, the general pelletization of water, packing to get.
3. the preparation process of the Colestid traditional Chinese drug inspissation water-bindered pill according to claim 1, which is characterized in that wherein it is above-mentioned respectively at
Divide after decocting and filters the dregs of a decoction, strainer 80-100 mesh screens.
4. the preparation process of the Colestid traditional Chinese drug inspissation water-bindered pill according to claim 1, which is characterized in that each ingredient in being wherein formulated
It is temperature (50-60 DEG C), vacuum degree -0.07~-0.08MPa that condition is concentrated after decoction.
5. the preparation process of the Colestid traditional Chinese drug inspissation water-bindered pill according to claim 1, which is characterized in that wherein above-mentioned recycling
Ethyl alcohol condition is steam pressure:0.2-0.4mpa, vapor (steam) temperature:100-120℃.
6. the preparation process of the Colestid traditional Chinese drug inspissation water-bindered pill according to claim 1, which is characterized in that wherein above-mentioned decompression
Concentration condition is 50-60 DEG C of temperature, vacuum degree -0.07~-0.08MPa.
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CN201810734701.6A CN108635426A (en) | 2018-07-06 | 2018-07-06 | A kind of Colestid traditional Chinese drug inspissation water-bindered pill and preparation process |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN117180340A (en) * | 2023-11-08 | 2023-12-08 | 吉林华康食元生物科技有限公司 | Composition for reducing blood fat and preparation method and application thereof |
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2018
- 2018-07-06 CN CN201810734701.6A patent/CN108635426A/en not_active Withdrawn
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN117180340A (en) * | 2023-11-08 | 2023-12-08 | 吉林华康食元生物科技有限公司 | Composition for reducing blood fat and preparation method and application thereof |
CN117180340B (en) * | 2023-11-08 | 2024-04-26 | 吉林华康食元生物科技有限公司 | Composition for reducing blood fat and preparation method and application thereof |
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Application publication date: 20181012 |