CN108524673A - A kind of Chinese medicine composition and its application - Google Patents

A kind of Chinese medicine composition and its application Download PDF

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CN108524673A
CN108524673A CN201810775217.8A CN201810775217A CN108524673A CN 108524673 A CN108524673 A CN 108524673A CN 201810775217 A CN201810775217 A CN 201810775217A CN 108524673 A CN108524673 A CN 108524673A
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chinese medicine
medicine composition
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concentrate
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牛志刚
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Beijing And Tong Shijia Investment Management Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00Antineoplastic agents
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    • A61P37/02Immunomodulators
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    • AHUMAN NECESSITIES
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    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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Abstract

The present invention relates to a kind of Chinese medicine composition and its application, which is made of the raw material including following parts by weight:1 20 parts of 1 10 parts of ginseng, 1 10 parts of chrysanthemum, 1 10 parts of cassia seed, 1 20 parts of dried orange peel and the fruit of Chinese wolfberry;Chinese medicine composition of the present invention can significantly improve sub-health condition of human body, have significant curative effect to cardiovascular and cerebrovascular disease, disease of digestive system and metabolic syndrome, and have no toxic and side effect to human body.

Description

A kind of Chinese medicine composition and its application
Technical field
The present invention relates to technical field of traditional Chinese medicines, in particular to a kind of Chinese medicine composition and its application.
Background technology
With the development of the society, people’s lives rhythm is constantly accelerated, stress is bigger than normal, and diet is irregular, and lacks Labour and exercise may result in people's appearance for a long time, and lassitude hypodynamia, four limbs are sleepy, dizziness is nose heave, palpitaition is nervous, reaction subtracts Slowly, the physically weak sub-health status such as susceptible;Currently, being directed to such case, without accurate drug therapy, the most selective enhancement body of people The health products of matter, however it is various in this kind of health products condition on the market, and specific aim is not strong, and effect is indefinite.
In addition, cardiovascular and cerebrovascular disease is the general designation of cardiovascular and cranial vascular disease, refer to since hyperlipidemia, blood are glutinous The ischemic or hemorrhagic disease that heart, brain and body tissue caused by thick, atherosclerosis, hypertension etc. occur. Cardiovascular and cerebrovascular disease is that one kind seriously threatening the mankind, and the common disease of especially 50 years old or more middle-aged and the old's health has high illness The characteristics of rate, high disability rate and high mortality, even if the treatment means that application is most advanced, perfect at present, can still there is 50% or more Cerebrovascular accident survivor life cannot take care of oneself completely, the number that cardiovascular and cerebrovascular disease is died of in the whole world every year is up to 15,000,000 It is the first to occupy the various causes of the death by people;There are many oral and drug administration by injection the drug for the treatment of cardiovascular and cerebrovascular diseases at present, but since this disease needs to grow The drug of phase medication, many conventional administrations will produce the adverse reactions such as gastrointestinal reaction, liver and kidney dysfunction, injection pain, shadow The compliance of patient's long-term administration is rung, while big drug needs are periodically periodically taken, the time has been grown also to patient with next life Inconvenience in work.
Metabolic syndrome refers to the pathology shape that metabolic disorder occurs for the substances such as the protein, fat, carbohydrate of human body State is a complex set of metabolic disorder disease group, is the risk factor for leading to diabetes cardiovascular and cerebrovascular disease;Currently, treatment generation It thanks to syndrome and uses the treatments such as fat regulation medicine, antidiabetic drug, antihypertensive more, but each medicine can only be directed to a certain of metabolic syndrome A or certain two pathology link.It is various that this results in patient medication type, increases adverse drug reaction and bad each other Reaction, and the financial burden of patient is increased, it is unfavorable for long-term treatment.
In view of this, special propose the present invention.
Invention content
The first object of the present invention is to provide a kind of Chinese medicine composition, which is acted synergistically by each raw material Sub-health condition of human body can be improved, and have to cardiovascular and cerebrovascular disease, disease of digestive system and metabolic syndrome and significantly treat Effect;In addition, having no toxic and side effect to human body.
The second object of the present invention is to provide a kind of Chinese medicine composition and is preparing treatment cardiovascular and cerebrovascular, digestive system or generation Thank to the application in syndrome drug.
The third object of the present invention is to provide a kind of cardiovascular and cerebrovascular, digestive system or metabolic syndrome drug, the drug Cardiovascular and cerebrovascular disease, disease of digestive system and metabolic syndrome can be effectively treated, therapeutic effect is notable, and nontoxic to human body Side effect.
In order to realize that the above-mentioned purpose of the present invention, spy use following technical scheme:
The first aspect of the present invention provides a kind of Chinese medicine composition, and object closes by including the raw materials of following parts by weight in Chinese medicine Soviet Union It is made:
1-20 parts of 1-10 parts of ginseng, 1-10 parts of chrysanthemum, 1-10 parts of cassia seed, 1-20 parts of dried orange peel and the fruit of Chinese wolfberry.
Each raw material used in the present invention is as follows:
Ginseng:Sweet in flavor, slight bitter, it is warm-natured, flat;Returns spleen, lung channel, the heart channel of Hang-Shaoyin;With tonifying Qi, prevent prolapse, promotes the production of body fluid, reinforces the spleen to benefit the lung, pacifies God, intelligence development and other effects;Cure mainly it is physically weak to be taken off, spleen eating less, the deficiency syndrome of the lung is breathed with cough, injury thirst, insomnia of palpitating with fear, and it is deficient to control internal lesion caused by overexertion, food It is few, burnout, regurgitation and emesis, palpitate with fear forgetful, dizziness and headache and perennial and irrecoverable weakness, the card of all qi-blood-body fluid deficiencies;《Legendary god of farming's book on Chinese herbal medicine Through》Think, ginseng has the effect of " tonifying five zang organs, soothe the nerves determine soul, stop palpitate with fear, remove pathogenic factor, the happy intelligence development of improving eyesight ", and long term usage is light Body macrobiosis.
Chrysanthemum:Bitter, sweet, cold nature;Return lung, Liver Channel;With relieve heat heat-clearing, flat liver improving eyesight, clearing heat and detoxicating and other effects;It is main The diseases such as the dim-sighted, sore and toxic of anemopyretic cold, dizziness of having a headache, red eye, swell pain, eyes are controlled, studies have shown that chrysanthemum is expansible coronal dynamic Arteries and veins, increase blood flow, blood pressure lowering, coronary artery dilator and antibacterial, long-term drinking can adjust myocardial function, reduce cholesterol, is right The excessively high disease of coronary heart disease, hypertension, artery sclerosis, serum cholesterol has notable curative effect;Also there is relaxation nerve simultaneously, releive The effect of headache.
Cassia seed:It is sweet in flavor, bitter, it is cold in nature, it is micro- salty;Return liver, large intestine channel;With clearing liver and improving vision, relax bowel and other effects;It cures mainly The diseases such as the dark unknown, constipation of the puckery pain of hot eyes, the more tears of photophobia, dizziness of having a headache, mesh;Studies have shown that also there is sharp water defaecation, delay It rushes down, blood pressure lowering and effect for reducing blood fat.
Dried orange peel:It is bitter, pungent, it is warm-natured;Return lung, the spleen channel;With regulating qi-flowing for strengthening spleen, eliminating dampness and eliminating phlegm and other effects;Cure mainly the taste stagnation of the circulation of vital energy Dampness, chest and diaphragm expire vexed, abdominal distention, do not feel like eating, the dirty inverse, difficulty in urination and defecation of vomiting, lung qi retardance, coughing with a lot of sputum, also control acute mastitis From the beginning of;Through for many years studies have shown that dried orange peel has significant curative effect to digestive system, cardiovascular and cerebrovascular, respiratory system.
The fruit of Chinese wolfberry:It is sweet in flavor, it is mild-natured;Return liver and kidney channel;With nourishing liver and kidney, sweet flat matter profit, benefiting shrewd head, flat filling liver kidney, taste Reinforcement is strong and other effects;Kidney deficiency and liver is cured mainly, the vertigo of blood and essence asthenia, hypopsia often match chrysanthemum, prepared rehmannia root, liver kidney yin The soreness and weakness of waist and knees of void, seminal emission, the deficiency of Yin such as are quenched one's thirst the diseases;Matrimony vine also have it is antifatigue, reduce blood pressure, liver protection, it is hypoglycemic, softening blood Pipe, the cholesterol in reduction blood, triglyceride levels, have certain curative effect to fatty liver and diabetic;According to clinic Medicine is verified, and matrimony vine can also treat chronic renal failure;In addition, the fruit of Chinese wolfberry can improve the ability that skin absorbs oxygen, and can rise It to whitening function, and improves the immunity of the human body, the toxic side effect of cyclophosphamide can be mitigated in antineoplaston, promote hematopoiesis Functional rehabilitation increases the leukocyte count of Peripheral blood, and protective effect is generated to body;Studies have shown that polysaccharides is to experimental liver Damage has protective effect, can reduce serum glutamic pyruvic transminase, promote the reparation of hepatic injury, and can inhibit fat in liver cell Deposition promotes liver cell newborn.
It will be upper according to the physicochemical property of the property feature of each raw material and each material effective component, pharmacological activity in the present invention The specific dosage that specified raw material is combined and limits each raw material is stated, realizes the synergistic effect of each raw material, drug effect of mutually promoting hair It waves, can significantly improve sub-health condition of human body, have to cardiovascular and cerebrovascular disease, disease of digestive system and metabolic syndrome aobvious Curative effect is write, and is had no toxic and side effect to human body.
Further, the Chinese medicine composition is made of the raw material including following parts by weight:
5-15 parts of 3-8 parts of ginseng, 2-7 parts of chrysanthemum, 3-8 parts of cassia seed, 3-6 parts of dried orange peel and the fruit of Chinese wolfberry;
Preferably, the Chinese medicine composition is made of the raw material including following parts by weight:
10 parts of 5 parts of ginseng, 4 parts of chrysanthemum, 5 parts of cassia seed, 4 parts of dried orange peel and the fruit of Chinese wolfberry.
Pass through the specific selection of each raw material dosage so that the synergy between each raw material is more notable, further advantageous In the promotion of Chinese medicine composition health-care efficacy.
Further, the Chinese medicine composition further includes 1-10 parts of lemon;
Preferably, the lemon is 2-7 parts.
In the present invention lemon rich in vitamin C, citrin, carbohydrate, calcium, phosphorus, iron, vitamin B1, vitamin B2, niacin, Quininic acid, citric acid, malic acid, aurantiamarin, aurantiin, coumarin, a large amount potassium element and low amounts sodium element etc., very to human body It is beneficial;Wherein, vitamin C and citrin can enhance blood vessel elasticity and toughness, can prevent and treat hypertension and myocardial infarction Symptom;And the preventing phlegm from forming and stopping coughing of vitamin C energy, stomach invigorating of promoting the production of body fluid;To bronchitis, pertussis, loss of appetite, hypovitaminosis, in The symptoms such as heat polydipsia have certain curative effect;Studies have shown that lemon has the effects that preventing cold, stimulation hematopoiesis and anticancer;And Containing a kind of ingredient of approximate insulin in green lemon, abnormal plasma glucose value can be reduced.
The present invention can preferably adjust body by the addition of lemon so that each material effective component gives full play to work With preferably playing the overall efficacy of the Chinese medicine composition.
In the present invention stringent limitation is not done to the type of the Chinese medicine composition, for example, the Chinese medicine composition can be Medicine materical crude slice, powder or extract made of each raw material;
Preferably, the extract is decocted by each raw material, is filtered, is concentrated to give concentrate;Concentrate is carried out again Dry, crushing obtains;
Preferably, the water additive amount of the decoction is 10-15 times of each raw material weight;The concentrate is at 60 DEG C, phase It is 1.20-1.25 to density.
By the way that medicine materical crude slice, powder or extract is made in each raw material, each raw material can be preferably leached during making tea Active ingredient improves the drug effect of the Chinese medicine composition.
A kind of above-mentioned Chinese medicine composition of the second aspect of the present invention offer is preparing treatment cardiovascular and cerebrovascular, digestive system or generation Thank to the application in syndrome drug;
Preferably, the metabolic syndrome is hyperglycemia metabolic syndrome.
The third aspect of the present invention provides a kind of drug for treating cardiovascular and cerebrovascular, digestive system or metabolic syndrome, including The Chinese medicine composition and pharmaceutically acceptable auxiliary material of therapeutically effective amount;
Preferably, the auxiliary material content is 0.15%-35%;
Preferably, the auxiliary material in Icing Sugar, microcrystalline cellulose, starch, dextrin any one or more.
In the present invention by by above-mentioned Chinese medicine composition in the drug, can effectively treat cardiovascular and cerebrovascular disease, Disease of digestive system and metabolic syndrome, and therapeutic effect is notable, has no toxic side effect;It, can not only by the addition of auxiliary material It is enough prepared into the Chinese medicine of different dosage forms, and effective ingredient can be promoted to discharge and absorb in vivo, and then improves and controls Therapeutic effect.
The dosage form of the drug is not limited strictly in the present invention, it is preferable that the pharmaceutical dosage form includes but unlimited In medicinal tea, pill, granule, capsule, tablet, powder, paste, oral solutions and syrup;It is highly preferred that the drug agent Type is medicinal tea, granule, capsule or tablet.
The fourth aspect of the present invention provides a kind of preparation method of said medicine, includes the following steps:
The Chinese medicine composition is decocted, filtered, is concentrated to give concentrate;
Above-mentioned concentrate is dried, crushes and obtains extract powder;
Auxiliary material is added in extract powder, pharmaceutical preparation is made.
By above-mentioned specific preparation method, the active ingredient in each raw material can be adequately extracted, and by crushing To extract powder, the drug being prepared can more preferably be absorbed by the body faster, and effective component of chinese medicine is avoided to change in vivo Learning reaction reduces drug effect.
In the above-mentioned preparation method of the present invention, it is preferable that the water additive amount of the decoction is Chinese medicine composition weight 1-20 times;The drying temperature is 60-80 DEG C;It is described to be crushed to 80 mesh or more;Preferably 80-100 mesh.
Preferably, the water additive amount of the decoction is 10-15 times of Chinese medicine composition weight.
By the limitation to water additive amount, each middle the effective elements of the medicine can be preferably extracted.
Preferably, the concentrate is at 60 DEG C, relative density 1.20-1.25.
Compared with prior art, beneficial effects of the present invention include at least:
(1) Chinese medicine composition of the present invention is according to the property feature of each raw material and the physics and chemistry of each material effective component Above-mentioned specified raw material is combined and is limited the dosage of each raw material by matter, pharmacological activity, realizes the synergistic effect of each raw material, phase Mutually drug effect is promoted to play, can significantly improve sub-health condition of human body, and to cardiovascular and cerebrovascular disease, disease of digestive system and Metabolic syndrome has significant curative effect, and has no toxic and side effect to human body.
(2) drug of the present invention can effectively treat cardiovascular and cerebrovascular disease, disease of digestive system and metabolic syndrome, Therapeutic effect is notable, has no toxic side effect;And also have the function of antitumor, raising immunity of organisms and anti-aging.
Specific implementation mode
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will Understand, the following example is merely to illustrate the present invention, and is not construed as limiting the scope of the invention.It is not specified in embodiment specific Condition person carries out according to conventional conditions or manufacturer's recommended conditions.Reagents or instruments used without specified manufacturer is The conventional products obtained can be bought by city.
Embodiment 1
The present embodiment provides a kind of Chinese medicine compositions, are made of the prepared slices of Chinese crude drugs of following parts by weight:3 parts of ginseng, chrysanthemum 3 Part, 3 parts of cassia seed, 6 parts of dried orange peel, 5 parts of the fruit of Chinese wolfberry and 3 parts of lemon.
Embodiment 2
The present embodiment provides a kind of Chinese medicine compositions, are made of the herb powder of following parts by weight:8 parts of ginseng, chrysanthemum 7 Part, 8 parts of cassia seed, 6 parts of dried orange peel, 15 parts of the fruit of Chinese wolfberry and 7 parts of lemon.
Embodiment 3
The present embodiment provides a kind of Chinese medicine compositions, are made of the Chinese medical extract of following parts by weight:5 parts of ginseng, chrysanthemum 4 Part, 5 parts of cassia seed, 4 parts of dried orange peel and 10 portions of the fruit of Chinese wolfberry, 5 parts of lemon.
Embodiment 4
The present embodiment provides a kind of drugs for treating cardiovascular and cerebrovascular, digestive system or metabolic syndrome, including treatment is effective Chinese medicine composition in the embodiment 1 of amount and pharmaceutically acceptable auxiliary material;
The auxiliary material is starch, and content is 15%;
The preparation method of said medicine, includes the following steps:
Each raw material in embodiment 1 is decocted, is filtered, is concentrated to give concentrate, concentrate is relatively close at 60 DEG C Degree is 1.22;Wherein, the water additive amount of decoction is 15 times of each raw material weight;.
Above-mentioned concentrate is dried under the conditions of 60 DEG C, is then crushed to 80 mesh extract powder derived above;
Microcrystalline cellulose is added in extract powder, tablet is made.
Embodiment 5
The present embodiment provides a kind of drugs for treating cardiovascular and cerebrovascular, digestive system or metabolic syndrome, including treatment is effective Chinese medicine composition in the embodiment 2 of amount and pharmaceutically acceptable auxiliary material;
The auxiliary material is starch and dextrin, and the auxiliary material content is 20%;
The preparation method of said medicine, includes the following steps:
Each raw material in embodiment 2 is decocted, is filtered, is concentrated to give concentrate, concentrate is relatively close at 60 DEG C Degree is 1.22;Wherein, the water additive amount of decoction is 20 times of each raw material weight;.
Above-mentioned concentrate is dried under the conditions of 80 DEG C, is then crushed to 100 mesh extract powder derived above;
Starch is added in extract powder and granule is made in dextrin.
Embodiment 6
The present embodiment provides a kind of drugs for treating cardiovascular and cerebrovascular, digestive system or metabolic syndrome, including treatment is effective Chinese medicine composition in the embodiment 3 of amount and pharmaceutically acceptable auxiliary material;
The auxiliary material is microcrystalline cellulose, and the auxiliary material content is 25%;
The preparation method of said medicine, includes the following steps:
It is 1.25 that each raw material in embodiment 3, which is decocted, is filtered, is concentrated into the relative density at 60 DEG C, is obtained dense Contracting liquid;Wherein, the water additive amount of decoction is 10 times of each raw material weight;.
Above-mentioned concentrate is dried under the conditions of 80 DEG C, is then crushed to 100 mesh extract powder derived above;
Microcrystalline cellulose is added in extract powder, medicinal tea is made.
Embodiment 7
The present embodiment provides a kind of drugs for treating cardiovascular and cerebrovascular, digestive system or metabolic syndrome, including treatment is effective Chinese medicine composition in the reference examples 1 of amount and pharmaceutically acceptable auxiliary material;
The auxiliary material is microcrystalline cellulose, and the auxiliary material content is 25%;
The preparation method of said medicine is identical as the process for preparing medicine of embodiment 6.
Reference examples 1
The present embodiment provides a kind of Chinese medicine composition, which is made of the Chinese medical extract of following parts by weight, ginseng 15 parts, 0.5 part of chrysanthemum, 5 parts of cassia seed, 4 parts of dried orange peel and 0.5 portion of the fruit of Chinese wolfberry, 5 parts of lemon.
Experimental example 1
The effect of Chinese medicine composition in embodiment 1-3 and reference examples 1, is measured, measurement result is shown in Table 1.
400 patients are chosen as experimental subjects, selection mode is, the equal readme of outpatients have the following problems in extremely Few one kind:Lassitude hypodynamia, four limbs are sleepy, dizziness is nose heave, palpitaition is nervous, reaction slows down, is physically weak susceptible;But it is examined through clinical whole body It surveys and laboratory examination does not go out any pathologic or physiological disorder;
Above-mentioned patient is divided into four groups, every group of 100 people, first group of Chinese medicine composition for drinking embodiment 1;Second group is drunk The Chinese medicine composition of embodiment 2;Third group drinks the Chinese medicine composition of embodiment 3;The 4th group of Chinese traditional medicine composition for drinking reference examples 1 Object;
Drinking method:One time a day, each 5g is brewed using 100 DEG C of boiling water, brewing time at least 10 minutes, and And it brews twice;It persistently takes 50 days.
Judgment criteria:
(1) effective:Symptom disappearance, arousing brain, raising spirit;
(2) effectively:Symptom has alleviation, but still has a degree of illness;
(3) invalid:Illness is even aggravated without improving completely.
1 each embodiment of table and reference examples health-care efficacy testing result
Group Effective (people) Effectively (people) (people) in vain
First group 46 49 5
Second group 50 48 2
Third group 49 48 3
4th group 41 45 14
As shown in Table 1
4th group equally has the function of improving inferior health disease, but the 4th group of effective percentage is substantially less than having for 1-3 groups Efficiency, it is seen then that Chinese medicine composition of the present invention can significantly treat inferior health disease, moreover, limiting range in each raw material of the present invention Interior synergy is best, most pronounced effects.
Experimental example 2
Effect to the drug in embodiment 4-7 in treatment hypertension metabolic syndrome is measured, and measurement result is shown in Table 2.
Hypertension metabolic syndrome patient 200 is chosen, the age is 32-68 Sui, is randomly divided into 4 groups, every group of 50 people.
First group of drug for taking embodiment 4;Second group of drug for drinking embodiment 5;Third group drinks the medicine of embodiment 6 Object;The 4th group of drug for drinking embodiment 7;
Instructions of taking:2 times a day, each 5g, first group and second group is taken by the way of oral, and sooner or later It is each primary;Third group and the 4th group are brewed using 100 DEG C of boiling water, brewing time at least 10 minutes, and are brewed twice, Once in the morning and once at night;It persistently takes 60 days.Check that waistline (WC), fasting insulin (FINS), FBG, insulin support after taking 60 days Anti- index (HOMA-IR), TC, TG, HDL-C, LDL-C.
Judgment criteria:
(1) effective:Blood glucose level, FPG < 6.1mmol/L, 2hPG < 7.8mmol/L;Lipids detection reaches following wantonly 1 Person, TC decline >=20%, TG and decline >=40%, HDL-C risings >=0.26mmol/L.
(2) effectively:Blood glucose level, FPG < 7.8mmol/L, 2hPG < 8.4mmol/L;Lipids detection reaches following wantonly 1 Person, TC decline >=10% but < 20%, and TG declines >=20% but < 40%, HDL-C risings >=0.104mmol/L but < 0.26mmol/L。
(3) invalid:The not up to above index person.
Every patient is judged according to judgment criteria, evaluation result is as shown in table 2:
Table 2
As shown in Table 2
Drug in the present invention can significantly improve the blood lipid level of hypertension metabolic syndrome patient, mitigates insulin and supports Anti- and obese state has notable curative effect to hypertension metabolic syndrome.
Finally it should be noted that:The above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations;To the greatest extent Present invention has been described in detail with reference to the aforementioned embodiments for pipe, but it will be understood by those of ordinary skill in the art that:Its It still can be with technical scheme described in the above embodiments is modified, either to which part or all technical features Carry out equivalent replacement;And these modifications or replacements, various embodiments of the present invention skill that it does not separate the essence of the corresponding technical solution The range of art scheme.

Claims (10)

1. a kind of Chinese medicine composition, which is characterized in that be made of the raw material including following parts by weight:
1-20 parts of 1-10 parts of ginseng, 1-10 parts of chrysanthemum, 1-10 parts of cassia seed, 1-20 parts of dried orange peel and the fruit of Chinese wolfberry.
2. Chinese medicine composition according to claim 1, which is characterized in that be made of the raw material including following parts by weight:
5-15 parts of 3-8 parts of ginseng, 2-7 parts of chrysanthemum, 3-8 parts of cassia seed, 3-6 parts of dried orange peel and the fruit of Chinese wolfberry;
Preferably, the Chinese medicine composition is made of the raw material including following parts by weight:
10 parts of 5 parts of ginseng, 4 parts of chrysanthemum, 5 parts of cassia seed, 4 parts of dried orange peel and the fruit of Chinese wolfberry.
3. Chinese medicine composition according to claim 1 or 2, which is characterized in that the raw material further includes 1-10 parts of lemon;
Preferably, the lemon is 2-7 parts.
4. according to claim 1-3 any one of them Chinese medicine compositions, which is characterized in that the Chinese medicine composition is each raw material Manufactured medicine materical crude slice, powder or extract;
Preferably, the extract is decocted by each raw material, is filtered, is concentrated to give concentrate;Concentrate is dried again, Crushing obtains;
Preferably, the water additive amount of the decoction is 10-15 times of each raw material weight;The concentrate is relatively close at 60 DEG C Degree is 1.20-1.25.
5. claim 1-4 any one of them Chinese medicine composition is preparing treatment cardiovascular and cerebrovascular, digestive system or Metabolic syndrome Levy the application in drug;
Preferably, the metabolic syndrome is hyperglycemia metabolic syndrome.
6. a kind of drug for treating cardiovascular and cerebrovascular, digestive system or metabolic syndrome, which is characterized in that comprising therapeutically effective amount The Chinese medicine composition and pharmaceutically acceptable auxiliary material;
Preferably, the auxiliary material content is 0.15%-35%;
Preferably, the auxiliary material in Icing Sugar, microcrystalline cellulose, starch, dextrin any one or more.
7. drug according to claim 6, which is characterized in that the pharmaceutical dosage form is medicinal tea, pill, granule, capsule Agent, tablet, powder, paste, oral solutions and syrup;
Preferably, the pharmaceutical dosage form is medicinal tea, granule, capsule or tablet.
8. the preparation method of the drug described according to claim 6 or 7, which is characterized in that include the following steps:
The Chinese medicine composition is decocted, filtered, is concentrated to give concentrate;
Above-mentioned concentrate is dried, crushes and obtains extract powder;
Auxiliary material is added in extract powder, pharmaceutical preparation is made.
9. preparation method according to claim 8, which is characterized in that the water additive amount of the decoction is Chinese medicine composition weight 1-20 times of amount;
Preferably, the water additive amount of the decoction is 10-15 times of Chinese medicine composition weight.
10. preparation method according to claim 8 or claim 9, which is characterized in that the concentrate is at 60 DEG C, relative density For 1.20-1.25.
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CN110447741A (en) * 2019-08-26 2019-11-15 甘肃岷归中药材科技有限公司 A kind of Qi yellow tea
CN110463800A (en) * 2019-08-26 2019-11-19 甘肃岷归中药材科技有限公司 A kind of four seasons tea
CN111011558A (en) * 2019-12-20 2020-04-17 高蕊 Tea drink composition for regulating glycolipid metabolism, eliminating plaque and protecting blood vessel elasticity
CN113647491A (en) * 2021-08-27 2021-11-16 曹国花 Beauty and health tea and preparation method thereof

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110447741A (en) * 2019-08-26 2019-11-15 甘肃岷归中药材科技有限公司 A kind of Qi yellow tea
CN110463800A (en) * 2019-08-26 2019-11-19 甘肃岷归中药材科技有限公司 A kind of four seasons tea
CN111011558A (en) * 2019-12-20 2020-04-17 高蕊 Tea drink composition for regulating glycolipid metabolism, eliminating plaque and protecting blood vessel elasticity
CN113647491A (en) * 2021-08-27 2021-11-16 曹国花 Beauty and health tea and preparation method thereof

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Application publication date: 20180914