CN102131830A - 嵌合呼吸道合胞病毒多肽抗原 - Google Patents

嵌合呼吸道合胞病毒多肽抗原 Download PDF

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Publication number
CN102131830A
CN102131830A CN2009801332745A CN200980133274A CN102131830A CN 102131830 A CN102131830 A CN 102131830A CN 2009801332745 A CN2009801332745 A CN 2009801332745A CN 200980133274 A CN200980133274 A CN 200980133274A CN 102131830 A CN102131830 A CN 102131830A
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rsv
polypeptide
chimeric
protein
immunogenic composition
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Chinese (zh)
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诺曼德.布莱斯
帕特里克.雷奥尔特
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ID Biomedical Corp of Quebec
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ID Biomedical Corp of Quebec
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/115—Paramyxoviridae, e.g. parainfluenza virus
    • C07K14/135—Respiratory syncytial virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
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    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN2009801332745A 2008-07-18 2009-07-17 嵌合呼吸道合胞病毒多肽抗原 Pending CN102131830A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8188808P 2008-07-18 2008-07-18
US61/081,888 2008-07-18
PCT/CA2009/001021 WO2010006447A1 (en) 2008-07-18 2009-07-17 Chimeric respiratory syncytial virus polypeptide antigens

Publications (1)

Publication Number Publication Date
CN102131830A true CN102131830A (zh) 2011-07-20

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ID=41549978

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CN2009801332745A Pending CN102131830A (zh) 2008-07-18 2009-07-17 嵌合呼吸道合胞病毒多肽抗原

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US (1) US20110177117A1 (enExample)
EP (1) EP2324062A4 (enExample)
JP (1) JP2011528222A (enExample)
KR (1) KR20110045008A (enExample)
CN (1) CN102131830A (enExample)
AU (1) AU2009270399A1 (enExample)
BR (1) BRPI0915960A2 (enExample)
CA (1) CA2731194A1 (enExample)
EA (1) EA201170217A1 (enExample)
IL (1) IL210493A0 (enExample)
MX (1) MX2011000668A (enExample)
WO (1) WO2010006447A1 (enExample)
ZA (1) ZA201100132B (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108265079A (zh) * 2017-01-02 2018-07-10 刘昕 一种新型呼吸道合胞体病毒pre-F融合蛋白载体的制备方法
CN113543803A (zh) * 2019-02-28 2021-10-22 Km生物医药股份公司 Rsv f/g嵌合疫苗
CN114685627A (zh) * 2020-12-28 2022-07-01 广州更新生物医药科技有限公司 一种预防呼吸道合胞病毒的rAAV载体疫苗
WO2025026448A1 (zh) * 2023-08-03 2025-02-06 广州穗和生物技术有限公司 修饰的呼吸道合胞病毒f蛋白及其用途

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ES2719406T3 (es) * 2007-12-24 2019-07-10 Id Biomedical Corp Quebec Antígenos recombinantes del VSR
WO2010149745A1 (en) 2009-06-24 2010-12-29 Glaxosmithkline Biologicals S.A. Recombinant rsv antigens
EP4218799A1 (en) 2009-07-15 2023-08-02 GlaxoSmithKline Biologicals S.A. Rsv f protein compositions and methods for making same
DK2590675T3 (en) 2010-07-07 2018-10-29 Artificial Cell Tech Inc ANTI-ANTI-COMPOSITIONS AND PROCEDURES FOR RESPIRATORY SYNCYTIAL VIRUS
TR201811280T4 (tr) * 2011-03-02 2018-08-27 Glaxosmithkline Biologicals Sa Düşük antijen ve/ veya adjuvan dozları olan karma aşılar.
WO2012158613A1 (en) 2011-05-13 2012-11-22 Novartis Ag Pre-fusion rsv f antigens
EP2968518A4 (en) * 2013-03-15 2016-08-24 Vlp Biotech Inc VIRAL TYPE PARTICLES BASED ON PALIVIZUMAB EPITOPE
CN105164155B (zh) * 2013-04-15 2020-01-03 扬森疫苗与预防公司 结合到rsv g蛋白的人类抗体
WO2014170257A1 (en) 2013-04-15 2014-10-23 Crucell Holland B.V. Human antibodies binding to rsv g protein
EP2873708B1 (de) 2013-11-19 2019-02-13 Artimelt AG Klebstoffzusammensetzung
SG10202001389PA (en) 2015-12-23 2020-04-29 Pfizer Rsv f protein mutants
CN109073639B (zh) 2016-02-03 2022-04-01 Cg探索股份有限公司 具有异源表位和/或改变的成熟切割位点的流感血凝素的组合物
US10063211B2 (en) * 2016-02-03 2018-08-28 Qualcomm Incorporated Compact bypass and decoupling structure for millimeter-wave circuits

Citations (2)

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US5194595A (en) * 1987-12-23 1993-03-16 The Upjohn Company Chimeric glycoproteins containing immunogenic segments of the glycoproteins of human respiratory syncytial virus
CN101952321A (zh) * 2007-12-24 2011-01-19 魁北克益得生物医学公司 重组rsv抗原

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US4866034A (en) * 1982-05-26 1989-09-12 Ribi Immunochem Research Inc. Refined detoxified endotoxin
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US5149650A (en) * 1986-01-14 1992-09-22 University Of North Carolina At Chapel Hill Vaccines for human respiratory virus
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Patent Citations (2)

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US5194595A (en) * 1987-12-23 1993-03-16 The Upjohn Company Chimeric glycoproteins containing immunogenic segments of the glycoproteins of human respiratory syncytial virus
CN101952321A (zh) * 2007-12-24 2011-01-19 魁北克益得生物医学公司 重组rsv抗原

Non-Patent Citations (1)

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GREGORY A. PRINCE ET AL.: "Efficacy and Safety Studies of a Recombinant Chimeric Respiratory Syncytial Virus FG Glycoprotein Vaccine in Cotton Rats", 《JOURNAL OF VIROLOGY》 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108265079A (zh) * 2017-01-02 2018-07-10 刘昕 一种新型呼吸道合胞体病毒pre-F融合蛋白载体的制备方法
CN113543803A (zh) * 2019-02-28 2021-10-22 Km生物医药股份公司 Rsv f/g嵌合疫苗
CN114685627A (zh) * 2020-12-28 2022-07-01 广州更新生物医药科技有限公司 一种预防呼吸道合胞病毒的rAAV载体疫苗
WO2025026448A1 (zh) * 2023-08-03 2025-02-06 广州穗和生物技术有限公司 修饰的呼吸道合胞病毒f蛋白及其用途

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EP2324062A4 (en) 2012-06-06
MX2011000668A (es) 2011-07-29
JP2011528222A (ja) 2011-11-17
BRPI0915960A2 (pt) 2019-09-24
EA201170217A1 (ru) 2011-08-30
CA2731194A1 (en) 2010-01-21
ZA201100132B (en) 2011-10-26
AU2009270399A1 (en) 2010-01-21
KR20110045008A (ko) 2011-05-03
WO2010006447A1 (en) 2010-01-21
US20110177117A1 (en) 2011-07-21
EP2324062A1 (en) 2011-05-25
IL210493A0 (en) 2011-03-31

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Application publication date: 20110720