CN102131530A - 聚异丁烯-氨基甲酸酯共聚物、聚异丁烯-脲共聚物和聚异丁烯-氨基甲酸酯/脲共聚物及含有这类共聚物的医疗器械 - Google Patents

聚异丁烯-氨基甲酸酯共聚物、聚异丁烯-脲共聚物和聚异丁烯-氨基甲酸酯/脲共聚物及含有这类共聚物的医疗器械 Download PDF

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Publication number
CN102131530A
CN102131530A CN2009801332209A CN200980133220A CN102131530A CN 102131530 A CN102131530 A CN 102131530A CN 2009801332209 A CN2009801332209 A CN 2009801332209A CN 200980133220 A CN200980133220 A CN 200980133220A CN 102131530 A CN102131530 A CN 102131530A
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China
Prior art keywords
segment
polyisobutylene
copolymer
group
polymer
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Pending
Application number
CN2009801332209A
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English (en)
Chinese (zh)
Inventor
S·德塞
M·C·施瓦兹
M·博登
M·克里希纳
M·C·史密斯
F·H·斯特里克勒
D·J·库克
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Cardiac Pacemakers Inc
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Cardiac Pacemakers Inc
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Filing date
Publication date
Application filed by Cardiac Pacemakers Inc filed Critical Cardiac Pacemakers Inc
Publication of CN102131530A publication Critical patent/CN102131530A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/62—Polymers of compounds having carbon-to-carbon double bonds
    • C08G18/6204—Polymers of olefins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08—Processes
    • C08G18/10—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08—Processes
    • C08G18/10—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
    • C08G18/12—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step using two or more compounds having active hydrogen in the first polymerisation step
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/4009—Two or more macromolecular compounds not provided for in one single group of groups C08G18/42 - C08G18/64
    • C08G18/4063—Mixtures of compounds of group C08G18/62 with other macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/4854—Polyethers containing oxyalkylene groups having four carbon atoms in the alkylene group
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/4858—Polyethers containing oxyalkylene groups having more than four carbon atoms in the alkylene group
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/65—Low-molecular-weight compounds having active hydrogen with high-molecular-weight compounds having active hydrogen
    • C08G18/6505—Low-molecular-weight compounds having active hydrogen with high-molecular-weight compounds having active hydrogen the low-molecular compounds being compounds of group C08G18/32 or polyamines of C08G18/38
    • C08G18/6511—Low-molecular-weight compounds having active hydrogen with high-molecular-weight compounds having active hydrogen the low-molecular compounds being compounds of group C08G18/32 or polyamines of C08G18/38 compounds of group C08G18/3203
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72—Polyisocyanates or polyisothiocyanates
    • C08G18/74—Polyisocyanates or polyisothiocyanates cyclic
    • C08G18/76—Polyisocyanates or polyisothiocyanates cyclic aromatic
    • C08G18/7657—Polyisocyanates or polyisothiocyanates cyclic aromatic containing two or more aromatic rings

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Materials For Medical Uses (AREA)
CN2009801332209A 2008-06-27 2009-06-26 聚异丁烯-氨基甲酸酯共聚物、聚异丁烯-脲共聚物和聚异丁烯-氨基甲酸酯/脲共聚物及含有这类共聚物的医疗器械 Pending CN102131530A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7632708P 2008-06-27 2008-06-27
US61/076,327 2008-06-27
PCT/US2009/048827 WO2009158600A1 (en) 2008-06-27 2009-06-26 Polyisobutylene urethane, urea and urethane/urea copolymers and medical devices containing the same

Publications (1)

Publication Number Publication Date
CN102131530A true CN102131530A (zh) 2011-07-20

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CN2009801332209A Pending CN102131530A (zh) 2008-06-27 2009-06-26 聚异丁烯-氨基甲酸酯共聚物、聚异丁烯-脲共聚物和聚异丁烯-氨基甲酸酯/脲共聚物及含有这类共聚物的医疗器械

Country Status (6)

Country Link
US (3) US20090326077A1 (enExample)
EP (1) EP2291204A1 (enExample)
JP (1) JP5592882B2 (enExample)
CN (1) CN102131530A (enExample)
AU (1) AU2009262097B2 (enExample)
WO (2) WO2009158600A1 (enExample)

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CN104602888A (zh) * 2012-09-11 2015-05-06 心脏起搏器股份公司 共形多孔薄层涂层与制造方法
US9926399B2 (en) 2012-11-21 2018-03-27 University Of Massachusetts High strength polyisobutylene polyurethanes
US10513576B2 (en) 2009-01-12 2019-12-24 University of Masschusetts Lowell Polyisobutylene-based polyurethanes
US10526429B2 (en) 2017-03-07 2020-01-07 Cardiac Pacemakers, Inc. Hydroboration/oxidation of allyl-terminated polyisobutylene
CN111479596A (zh) * 2018-01-17 2020-07-31 心脏起搏器股份公司 封端聚异丁烯聚氨酯
CN111902448A (zh) * 2018-03-26 2020-11-06 美敦力公司 聚(醚-碳酸酯)基聚合物以及医疗装置
CN111902449A (zh) * 2018-03-26 2020-11-06 美敦力公司 改性聚异丁烯基聚合物、制备方法以及医疗装置
US10835638B2 (en) 2017-08-17 2020-11-17 Cardiac Pacemakers, Inc. Photocrosslinked polymers for enhanced durability
CN112831013A (zh) * 2021-02-25 2021-05-25 中国科学院长春应用化学研究所 一种功能化聚氨酯及其制备方法和应用

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US7715922B1 (en) * 2005-11-16 2010-05-11 Pacesetter, Inc. Polyethylene oxide and polyisobutylene copolymers and their usage on medical devices
WO2007139199A1 (ja) * 2006-05-31 2007-12-06 Kaneka Corporation カテーテル用チューブ及びそれからなるカテーテル
WO2009158600A1 (en) * 2008-06-27 2009-12-30 Cardiac Pacemakers, Inc. Polyisobutylene urethane, urea and urethane/urea copolymers and medical devices containing the same
US20110213084A1 (en) * 2008-10-01 2011-09-01 The University Of Akron Polymers having both hard and soft segments, and process for making same
JP5775822B2 (ja) 2008-12-31 2015-09-09 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． ポリイソブチレンおよび生分解性ポリマーセグメントを持つコポリマー
CN102573940B (zh) 2009-08-21 2015-04-01 心脏起搏器公司 可交联聚异丁烯类聚合物及包含其的医疗装置
US8374704B2 (en) * 2009-09-02 2013-02-12 Cardiac Pacemakers, Inc. Polyisobutylene urethane, urea and urethane/urea copolymers and medical leads containing the same
US8644952B2 (en) 2009-09-02 2014-02-04 Cardiac Pacemakers, Inc. Medical devices including polyisobutylene based polymers and derivatives thereof
US8674034B2 (en) * 2009-11-11 2014-03-18 The University Of Akron Polyisobutylene-based polyurethanes, polyureas and/or polyurethane-polyureas and method for making same
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US8660663B2 (en) 2010-12-20 2014-02-25 Cardiac Pacemakers, Inc. Lead having a conductive polymer conductor
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US10285793B2 (en) * 2012-02-08 2019-05-14 Boston Scientific Scimed, Inc. Surgical scaffolds
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US20150025608A1 (en) 2013-07-22 2015-01-22 Cardiac Pacemakers, Inc. Lubricious, biocompatible hydrophilic thermoset coating using interpenetrating hydrogel networks
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US10314696B2 (en) 2015-04-09 2019-06-11 Boston Scientific Scimed, Inc. Prosthetic heart valves having fiber reinforced leaflets
US10426609B2 (en) 2015-04-09 2019-10-01 Boston Scientific Scimed, Inc. Fiber reinforced prosthetic heart valve having undulating fibers
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EP3286251B1 (en) * 2015-04-23 2019-02-20 Cardiac Pacemakers, Inc. Compositions and methods for copolymer solutions with high weight percent copolymers
US10716671B2 (en) 2015-07-02 2020-07-21 Boston Scientific Scimed, Inc. Prosthetic heart valve composed of composite fibers
US10413403B2 (en) 2015-07-14 2019-09-17 Boston Scientific Scimed, Inc. Prosthetic heart valve including self-reinforced composite leaflets
EP3325084B1 (en) 2015-07-25 2019-08-21 Cardiac Pacemakers, Inc. Medical electrical lead with biostable pvdf-based materials
US10195023B2 (en) 2015-09-15 2019-02-05 Boston Scientific Scimed, Inc. Prosthetic heart valves including pre-stressed fibers
CN119081064A (zh) * 2015-10-17 2024-12-06 心脏起搏器股份公司 原位可交联聚异丁烯-聚氨酯纳米纤维和涂层的生产
US20170327622A1 (en) * 2016-05-10 2017-11-16 Cardiac Pacemakers, Inc. Thermoset polyisobutylene-polyurethanes and methods for making
EP3457989B1 (en) 2016-05-19 2021-09-29 Boston Scientific Scimed, Inc. Prosthetic valves, valve leaflets and related methods
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CN110494170A (zh) 2017-04-25 2019-11-22 波士顿科学国际有限公司 生物相容性聚异丁烯-纤维复合材料和方法
KR102282617B1 (ko) * 2017-05-15 2021-07-28 다이너파워 컴퍼니 엘엘씨 태양광 에너지용 에너지 저장 시스템 및 태양광 에너지 저장 방법
US10899869B2 (en) 2019-01-24 2021-01-26 The University Of Akron Glycerol containing polyurethanes and polyurethane nanocomposites
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CN116057101A (zh) * 2020-08-06 2023-05-02 阿克伦大学 高分子量和强度的基于聚异丁烯的聚氨酯的合成及其用途

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