CN102113632B - Functional dairy cattle feed additive capable of preventing subclinical mastitis of dairy cattle - Google Patents
Functional dairy cattle feed additive capable of preventing subclinical mastitis of dairy cattle Download PDFInfo
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Abstract
The invention relates to the field of feed additives, in particular to a functional dairy cattle feed additive capable of preventing subclinical mastitis of dairy cattle. According to the functional dairy cattle feed additive, based on the total weight of the additive, the functional dairy cattle feed additive contains 2%-6% of organic selenium, 2%-6% of organic zinc, 4-8% of biological antioxidant, 8%-12% of mold adsorbent, 0.2%-0.6% of vitamins, 8%-12% of conventional additive for reducing the number of somatic cells, and 50%-80% of carrier. The invention provides the functional dairy cattle feed additive capable of preventing the subclinical mastitis of the dairy cattle and reducing the number of the somatic cells, the formula is reasonable, the nutrition is balanced, the number of the somatic cells in the dairy cattle can be effectively reduced, the incidence of the subclinical mastitis of the dairy cattle can be reduced, the good development mechanism of a mammary system can be maintained, and the milk yield and the milk quality of the dairy cattle can be improved.
Description
Technical field
The present invention relates to feed additive field, particularly, the present invention relates to a kind of functional milks ox feed additive that prevents cow subclinical mastitis.
Background technology
Mammitis is the most general disease of milk cow, can be divided into clinic mastitis and Subclinical mammitis according to its form of expression.The Subclinical mammitis claims again recessive mastitis, refers to breast and milk all without macroscopic variation, but the physicochemical properties such as milk conductance, body cell, pH value change, the mammitis that must just can detect with special physico-chemical method.Have data to show, approximately there are 2.2 hundred million cow heads in the whole world, and 33% suffers from various types of mammitises, and wherein the incidence of disease of recessive mastitis for milk cows is up to about 50%, and the incidence of China's mastitis for milk cows is higher.
Mastitis for milk cows is the inflammation of breast essence, a matter.The cause of disease is many by due to mechanical irritation, pathogenic microorganism immersion and chemistry, the physical injury.Mammitis is diseases maximum to cattle farm harm, that throwing people expenses for medicine is maximum, control is the most difficult, is listed in one of four large diseases of milk cow.Particularly recessive mastitis clinically without obvious symptom, need to just can detect with the proterties variation of special detection method according to milk.Recessive mastitis for milk cows at the incidence of disease of China between 40%~80%.When this disease makes milk yield reduce by 15%, also can reduce milk nutritional labeling and quality, affect health.This disease is not only serious to the loss that aquaculture causes, and also brings no small harm for human health.Mammitis is quite large to the loss that milk cow production causes, owing to containing a large amount of body cells and antibiotic in the milk, make fresh milk be subjected to a certain extent pollution, have a strong impact on quality and the local flavor of dairy products, reduce the fresh milk procurement price, mammitis also can cause the reduction of the output of milk simultaneously, affects whole parity even the lifelong output of milk.
A lot of to report in the various documents of detection, prevention and treatment of clinical mammitis, obtained certain effect, but to recessive mastitis except detection method, relevant prevention and treatment report are less.For this problem, the present inventor is through in many ways inquiring about and test of many times, developed a kind of functional milks ox feed additive that prevents cow subclinical mastitis, can effectively reduce somatic number in the milk, reduce the incidence of cow subclinical mastitis, safeguard the good developmental mechanism of mammary gland system, improve milk production of cow and milk-quality.
Summary of the invention
The purpose of this invention is to provide a kind of functional milks ox feed additive that prevents cow subclinical mastitis.
Functional milks ox feed additive according to prevention cow subclinical mastitis of the present invention, based on the gross mass of described additive, it comprises: reduction somatic number purpose additive 8%~12%, the carrier 50%~80% of Organic Selenium 2%~6%, organic zinc 2%~6%, biological anti-oxidant 4~8%, mould bacteria adsorbent 8%~12%, vitamin 0.2%~0.6%, routine.
Preferably, according to functional milks ox feed additive of the present invention, described additive package contains reduction somatic number purpose additive 10%, vitamin 0.4%, the carrier 65.6% of Organic Selenium 4%, organic zinc 4%, biological anti-oxidant 6%, mould bacteria adsorbent 10%, routine.
According to functional milks ox feed additive of the present invention, wherein, described Organic Selenium is the happy selenium of match; Described organic zinc is hundred happy zinc; Described biological anti-oxidant is biochemical fulvic acid; Described mould bacteria adsorbent is mould the suction; Described vitamin is vitamin E; Described carrier is one of in time powder and the zeolite powder or combination; The reduction somatic number purpose additive of described routine is that health breast is precious, and above raw material is all can be from the market enough.
It is formulated that feed addictive of the present invention is based on the cooperative effect of said components.
Match happy selenium and be in the world unique Organic Selenium through food and drug administration (FDA) authentication, it is the selenium yeast product of being produced by a kind of yeast of peculiar strain (Saccharomyces Cerevisiae CNCM 1-3060), is present unique yeast strain that gets the Green Light.The selenium element of matching in the happy selenium exists with its native form in plant, can be digested better and retain in animal body, thereby help improve animal in the production performance of stages, and need not face the threat of toxicity and the adverse effect that environment is caused.Selenium also participates in the formation of the synthetic and tissue of protein, studies confirm that, the animal energy metabolism changes behind the use Organic Selenium, and milk production of cow is significantly increased.It had just excreted before playing a role unlike inorganic selenium or artificial synthetic selenium, but can store in animal body and discharge when animal needs.Because yeast selenium is present in polypeptide form in the protein of yeast cells, therefore is protected, and can in cud, be degraded.So, relatively match organic selenium source that happy selenium is a kind of safer higher bioavailability with the selenium in inorganic source.
Zinc is the root element in the keratin building-up process, so the shortage of zinc often causes and contains high keratic epithelial tissue generation pathology.Mammary gland (pipe) surface coverage keratin, and latex dust also can be secreted keratin mucus and seals latex dust after each lactation.Therefore keratin is the first defence that lactating cow prevents intramammary infection.In this process, approximately there is 50% keratin to discharge with milk at every turn and loses (mechanical milking is more serious).When keratin loses, need to be replenished rapidly, cause that simultaneously bacterium infects and the milk somatic cell number increased then cause the raising of the mastitis for milk cows incidence of disease and affect quality and the output of milk of milk otherwise can cause that latex dust has a superficial wound.In addition, the multiparity ox reduces the malabsorption that reaches mineral matter because of protein synthesis rate, so that the synthetic deficiency of mammary gland and latex dust Epidermal Keratin can't provide epithelial cell enough protections, and the milk somatic cell number is increased.
Hundred happy zinc are protein chelated zincs of making through modern means of science and technology production with biological raw material, after zinc is in conjunction with different amino acid and little peptide, form organic zinc, the absorption approach that its absorption can see through mucous membrane of small intestine amino acid and little peptide enters in the tissue, its biological chelate structure is stable, be not subject to the impact of external environment and change its solubility and be not subject to the interference of other mineral matter, therefore hundred happy zinc have best bioavailability.Hundred happy zinc do not have the bad flavor of other chemical chelating product simultaneously, and natural production process makes hundred happy zinc have good palatability on the contrary.
The main biological effect of vitamin E is antioxidation; can suppress and slow down oxidation and the peroxidating of polyunsaturated fatty acid in the body; in and the free radical that forms in the oxidizing process; the integrality of Cell protection and organelle lipid membrane structure and stability are kept muscle, nerve and peripheral vascular normal function.TD can cause polyunsaturated fatty acid over oxidation in the body, cell membrane and lysosome membrane suffer damage to discharge various lysosomal enzymes, such as GRD beta-glucuronidase, beta galactose enzyme, cathepsin etc., cause the retrogression pathological changes such as sex change of organ-tissue.
The present inventor finds Organic Selenium, organic zinc, the compound feeding cow of vitamin after deliberation, and the effect that can produce Synergistic reduces the body cell number.Zinc, selenium and vitamin E have synergy in anti-oxidant.Glutathione-the peroxidase that contains selenium decomposes established peroxide, has stoped the generation that may cause the snperoxiaized light basic free radical of membrane lipid and singlet oxygen; And the chain reaction of vitamin E block film lipid peroxidation has reduced the formation of peroxide, prevents that responsive membrane lipid is subject to the damage of oxidation.Studies have shown that, vitamin E and selenium can reduce the incidence of disease of clinic mastitis, and shorten the clinical symptoms duration.Use vitamin E and selenium and can strengthen milk cow to the premunition of mammitis, vitamin E and selenium may relate to the nonspecific defense mechanism of milk cow.The effect that vitamin E and selenium are prevented and treated mammitis is the most remarkable in early days in the lactation of milk cow.The lactation initial stage is mammitis incidence of disease peak phase, and this stage increases because of lactation, and particularly colostrum is discharged a large amount of tocopherols, and the resistance of mammary gland descends.The E that is deficient in vitamin in the dairy cow diet, the clinical mammitis incidence of disease raises; And when lacking selenium, the clinical mammitis duration is lasting, and when vitamin E and selenium acting in conjunction, the intramammary infection level significantly reduces.Vitamin E and selenium can strengthen the chemotaxis of polymorphonuclear leukocyte and promote its random transfer in blood and breast tissue.Diseases of Cow, the expression of the trophic factors in the blood, lymphocyte, neutral grain LA molecule all can change.The concentration of VitAVitE, Zn descends in the blood, and lymphocyte quantity reduces, and the reason that causes this result is that colostrum forms, and ruminal metabolism changed in perinatal period, even can directly cause the decline of milk cow human body immune function.Other neutral grain LA molecule CD6 in the blood between perinatal period
2+Concentration also can descend.Therefore, can effectively prevent and treat mastitis for milk cows to perinatal milk cow replenishing vitamins E and selenium.After the breast district of mammitis pathogen infected and causes the breast inflammation, Selenium Supplement centering grain leukocytoreaction speed was helpful.Compare with control group, mend in the milk cow of selenium, polymorphonuclear leukocyte flows into the speed in the breast district that is attacked, thereby makes the formation unit of Escherichia coli group of every liter of breast less.Therefore, in the milk cow of Selenium Supplement, infect not too seriously, and eliminate comparatively fast, lactation weight loss reduces.Replenishing vitamins E can increase and kills staphylococcus aureus and the colibacillary ability of dust Xi Shi in the ox blood in the polymorphonuclear leukocyte born of the same parents in the daily ration, but does not affect the ability that it engulfs bacterium.Free radical or peroxide that vitamin E and selenium retain in the scavenger soma effectively, thus promote the metabolism of eicosatetraenoic acid to increase mammary gland body cell quantity, improve immune cell function.
Biochemical fulvic acid is that simulating nature circle humic acid forms environment, from specific multiple-microorganism bacterial classification inoculation to plant culture, by the high-purity humic acid preparation that specific biooxidation reactions generates, the humic acid of its generation is take the soluble fulvic acid of little molecule as main.Biochemical fulvic acid is the condensation polymer of a kind of multivalence phenol type aromatic compound and nitrogen compound, contain the multiple functional groups such as phenolic hydroxyl group, carboxyl, alcoholic extract hydroxyl group, hydroxyquinone, enol base, sulfonic group, amino, free quinonyl, half quinonyl, quinone hydrogen base, methoxyl group, labyrinth with higher multiple functional group of biochemical fulvic acid makes it have stronger cation exchange capacity (CEC), complexing power, buffer capacity, adsorption capacity and catalytic capability.
Conventional reduction somatic number purpose additive such as health breast are precious; be a kind of milk cow special-purpose non-toxic feed addictive; its main component is from cultivating the high-activity biological protease that a kind of microorganism obtains in the spider body; this enzyme has very strong antibiotic, anti-infection activity and protein breakdown ability; can effectively prevent bacillary mammitis; strengthen the milk cow body immunity, significantly reduce body cell and improve the output of milk.
The present inventor is through the discovery that studies for a long period of time, compound interpolation biochemical fulvic acid and health breast treasured can reduce the incidence of disease of cow recessive mastitis in dairy cow diet, has preferably result for the treatment of for clinic mastitis, no drug residue, stress not to the ox body, safe and reliable, can improve the output of milk and the dairy food quality of milk cow simultaneously, have synergistic function.
The mould suction is a kind of glucomannans through modifying that extracts from the yeast cells inwall.It can adsorb different types of mycotoxin, such as aflatoxin, Gibberella zeae toxin, T-2 toxin, ochracin etc.It can effectively reduce mycotoxin to the infringement of animal body by the effective absorption to mycotoxin, strengthens the animal immune function, effectively reduces the incidence of milk cow miscarriage, stillborn foetus, improves the output of milk and milk-quality.And absorbing mycotoxin effectively under acid and condition of neutral pH, this puts very important.
Inferior powder and zeolite powder are commercially available, and through after the assay was approved, use as carrier.
Functional milks ox feed additive of the present invention has been strengthened trophism and the effect of various materials more with its unique proportioning combination.The interpolation of organic zinc in the additive of the present invention, the problems that caused because of zinc deficiency more than effectively having solved, and zinc, selenium and vitamin E have synergy in anti-oxidant.
Thereby the present invention forms for the prescription that the multiple recessive mastitis problem that solves present milk cow existence provides the functional feed of a kind of milk cow to add, and its advantage is:
1, added organic trace element by productions such as chelating amino acids technology (hundred happy zinc, match happy selenium), solved the low problem of inorganic microelement absorption rate, because trace element has improved absorption rate, strengthened the function of ductus papillaris keratoprotein, promoted the sealing of ductus papillaris, reduce the intrusion of breast pathogenic bacteria, reduced somatic number in the incidence of recessive mastitis and the milk.
2, the interpolation of vitamin E and selenium effectively promotes the growth of mammary gland and the recovery of breast tissue, is conducive to the enhancing of mammary gland function, improves the anti-infectious ability of breast tissue.
3, can effectively reduce mycotoxin to the infringement of animal body, strengthen the animal immune function, improve the output of milk.And absorbing mycotoxin effectively under acid and condition of neutral pH.
4, improve the output of milk of milk cow, reduce the incidence of disease of cow recessive mastitis, have preferably result for the treatment of for clinic mastitis, no drug residue, to the ox body stress not, safe and reliable.
In sum, the invention provides a kind of functional milks ox feed additive that prevents cow subclinical mastitis, reduces somatic number, its prescription rationally, balanced in nutrition, can effectively reduce somatic number in the milk, reduce the incidence of cow subclinical mastitis, safeguard the good developmental mechanism of mammary gland system, improve milk production of cow and milk-quality.
Description of drawings
Fig. 1 respectively organizes the average output of milk changing trend diagram of cows the different tests date.
Fig. 2 respectively organizes cows body cell changing trend diagram the different tests date.
Fig. 3 is for respectively organizing cows butterfat percnetage comparison diagram before and after the test.
Fig. 4 is for respectively organizing cows protein content comparison diagram before and after the test.
Fig. 5 is for respectively organizing cows lactose content comparison diagram before and after the test.
Before and after testing, Fig. 6 respectively organizes cows dry matter content comparison diagram.
Fig. 7 is that the various combination additive is on the impact of the average output of milk of tested cows.
Fig. 8 is that the various combination additive is on the impact of tested cows average body cell number.
The specific embodiment
Below describe technology of the present invention and characteristics in detail by specific embodiment, but these embodiment limit protection scope of the present invention.
The selection of each raw material all meets the concerned countries standard among the following embodiment.
Prepare this kind cow feed additive according to following ratio: match happy selenium 2%, hundred happy zinc 2%, biochemical fulvic acid (BFA powder) 4%, mouldly inhale 8%, vitamin E 0.2%, health breast are precious 8%, inferior powder 12%, zeolite powder 63.8%.
To match happy selenium, hundred happy zinc, biochemical fulvic acid (BFA powder), mould can suction, vitamin E, health breast treasured, inferior powder, weighing is good in proportion for zeolite powder, with mixer mixings generation in the 3-6 minute final products of premix unit.
Prepare this kind cow feed additive according to following ratio: match happy selenium 6%, hundred happy zinc 6%, biochemical fulvic acid (BFA powder) 8%, mouldly inhale 12%, vitamin E 0.6%, health breast are precious 12%, inferior powder 7.4%, zeolite powder 48%.
To match happy selenium, hundred happy zinc, biochemical fulvic acid (BFA powder), mould can suction, vitamin E, health breast treasured, inferior powder, weighing is good in proportion for zeolite powder, with mixer mixings generation in the 3-6 minute final products of premix unit.
Prepare this kind cow feed additive according to following ratio: match happy selenium 4%, hundred happy zinc 4%, biochemical fulvic acid (BFA powder) 6%, mouldly inhale 10%, vitamin E 0.4%, health breast are precious 10%, inferior powder 10%, zeolite powder 55.6%.
To match happy selenium, hundred happy zinc, biochemical fulvic acid (BFA powder), mould can suction, vitamin E, health breast treasured, inferior powder, weighing is good in proportion for zeolite powder, with mixer mixings generation in the 3-6 minute final products of premix unit.
The functional test test of cow feed additive of the present invention
In the optional test place functional milks ox feed additive of prevention cow subclinical mastitis reduction somatic number carried out feeding experiment.Duration of test, the product group of the present invention of feeding is compared the duration of test daily yielding and is on average improved 2.12kg with control group, body cell average is than testing the front lower 22.93 ten thousand/ml that fallen in the milk, therefore, the functional additive product effect of feed addictive prevention recessive mastitis of the present invention, reduction somatic number is remarkable, be worth promoting in practice, details are as follows for concrete process of the test.
1, experiment purpose
This test is intended to inquire into the milk cow functional feedstuff additive to the prevention recessive mastitis and reduces somatic effect, for setting up basic to the prevention of cow subclinical mastitis clinically.
2. material method
2.1 experimental animal and grouping
100 of good china holstein cowses are selected in test, according to similar principles such as somatic number, parity, the age in days of giving milk, lactation amount, body weight, are divided at random 5 groups, a control group, four test group, every group of 20 milking cows.
2.2 test products
Test products has four kinds, the first is that prevention recessive mastitis of the present invention reduces somatic functional feedstuff additive, and wherein every 100g contains: biological anti-oxidant 6g, mould bacteria adsorbent 10g, health breast precious 10g, biochemical fulvic acid 6g, Organic Selenium 4g, zinc 4g and vitamin E 0.4g; The second is that the somatic feedstuff additive product health breast of can reducing of Korea S's production is precious; The third is biochemical fulvic acid (BFA powder); The 4th kind is Organic Selenium, organic zinc and vitamin E combined additive.
2.3 test is processed
Each organizes basal diet, and to keep original daily ration level constant, and managerial skills are consistent, add respectively four kinds of functional additives in four test group daily rations, and control group does not add.60 days experimental periods.
Table 2-1 test disposition statistical form
2.4 testing index and detection method
2.4.1 the output of milk is measured
Adopt milk Room formula to concentrate and milk the jigger counting; Milk for one day three times, the early, middle and late sum of accumulative total is one day output of milk.Two days individual milk yield of METHOD FOR CONTINUOUS DETERMINATION are averaged and are counted once individual milk production of cow.
2.4.2 conventional ingredients in milk analysis
Adopt milk sample once every 10 days, get early, middle and late three aggregate samples of milking in 4: 3: 3 ratios.On-the-spot adding preservative agent 1-2 drips 4 ℃ of preservations.Adopt the milk composition automatic analyzer to measure the conventional ingredients in milks such as butterfat percnetage (Fat), lactoprotein (Pro), lactose (Lac), milk dry matter (DM).
2.4.3 body cell detects
Adopt body cell numeration instrument (Somacount 150), simultaneously above-mentioned newborn sample is carried out the body cell numeration in the newborn routine of survey.
2.5 statistical analysis
Use SPSS 10 softwares the data that obtain are processed, the oneway-ANOVA variance analysis, significant difference then carries out multiple ratio with LSD.
3. test results and analysis
3.1 the basic data of cows before the test
Before the experiment beginning, at first the basic data of experiment cows is investigated, the indexs such as the age in days of giving milk, parity, daily milk yield and the milk-quality thereof of every ox such as butterfat percnetage, lactoprotein, lactose, milk dry matter have been recorded, particularly measured body cell quantity in the milk, the result is presented between control group and each group of experiment, the These parameters there was no significant difference.
Table 3-1: cows statistical reliability data table before the test
3.2 functional additive of the present invention is on the impact of milk production of cow
Duration of test, behind the various functional additives of each group test Cow-feeding, the result shows that each test group daily yielding is compared all with control group and is improved, experimental group A compares duration of test and on average improves 2.12kg kg/d head with control group; Experimental group B compares duration of test and on average improves 0.82kg kg/d head with control group; Experimental group C compares duration of test and on average improves 0.65kg kg/d head with control group; Experimental group D compares duration of test and on average improves the 0.53kgkg/d head with control group; Experimental group A improves the most remarkable.
(1) test group A product from on-test to 30d, the milk cow average daily milk production is obvious ascendant trend, on average increase day by day milk 1.27kg; Later stage, each the experimental group cows of increase with the age in days of giving milk all presented the nature downward trend, but test group A compares with control group, and decrease speed is slow, and the per day output of milk of whole test period is remarkable increase trend.
(2) experimental group B from on-test to 20d, held stationary before and after the per day output of milk of milk cow, the output of milk also presents normal decline with the age in days of giving milk and becomes behind the 30d, but compares with control group, whole experimental period daily yielding still present ascendant trend.
(3) experimental group C and experimental group D are at test basic held stationary in early stage, and later stage begins to descend, but population mean is higher than control group, and the per day output of milk has increase.Different experiments group per day output of milk ascendant trend of whole experimental period sees table 3-2, Fig. 1 for details.
Table 3-2: the different tests date is respectively organized output of milk statistical form (kg/d head)
Annotate: be marked with the expression significant difference * number
3.3 functional additive is on the impact of somatic number in the milk
After adding the functional additive of four kinds of prevention recessive mastitis in the dairy cow diet, different-effect is arranged all.Wherein body cell average ratio is tested the front lower 22.93 ten thousand/ml that fallen in the experimental group A milk; Body cell average is than testing the front lower 2.37 ten thousand/ml that fallen in the experimental group D milk; Experimental group B compares the test front and back all less than decline with experimental group C, but compares with control group, and is whole on a declining curve.From whole experimental period variation tendency, the body cell downward trend is compared significant difference with other experimental group in the experimental group A milk, according to the indirect corresponding relation that body cell quantity and recessive mastitis in the milk occur, somatic number reduces and reduces with regard to respective description cow subclinical mastitis illness rate.The statistical analysis of body cell quantity sees Table 3-3, Fig. 2 in each experimental group milk.
Table 3-3: the different tests date is respectively organized somatic number statistical form (10 in the milk
4Individual/milliliter)
Annotate: upper table indicates the expression significant difference of different letters
3.4 functional additive is on the impact of butterfat, lactoprotein and Ruzhong dry
Table 3-4: respectively organize milk conventional index statistical form (%) before and after the test
Can find out from table 3-4 and Fig. 3,4,5,6, add the functional additive of four kinds of prevention recessive mastitis in the dairy cow diet, body cell quantity and increasing in the output of milk in reducing milk, do not reduce the content of butterfat percnetage in the milk, lactoprotein, lactose and dry, and the indices of experimental group A all there is raising in various degree.
3.5 functional additive is on the impact of milk cow palatability
Feeding of functional additive is to add in addition on the basis of original daily ration in the experimental design, because four kinds of test products have its distinctive smell, it is bad that palatability appears in the test group milk cow initial stage, milk cow dry matter intake decline situation, but feed intake is not done statistics in the test, after milk cow adapted to gradually in 3-5 days, search for food and recover normal, statistics shows 85% ox and no longer includes the food refusal phenomenon, therefore, functional additive is stirred and evenly mixed in fine fodder, can not affect the palatability of milk cow.
Mammitis is quite large to the loss that milk cow production causes, owing to containing a large amount of body cells and bacterium in the milk, make fresh milk be subjected to a certain extent pollution, have a strong impact on quality and the local flavor of dairy products, reduce the fresh milk procurement price, mammitis also can cause the reduction of the output of milk simultaneously, affects whole parity even the lifelong output of milk, that therefore, takes in production practices that positive preventive means reduces recessive mastitis seems particularly important.The present invention explores and add functional additive prevention recessive mastitis in dairy cow diet, has obtained preferably test effect.
Feed addictive of the present invention has been strengthened the nutrition of vitamin such as VE, the micronutrient element such as organic zinc, Organic Selenium and efficient mold toxin sorbent etc. have been added, behind the cow feeding, balance nutrition, improve absorption rate, increased the immunity of body, the function of acceleration ductus papillaris keratoprotein, promoted the timely closure of ductus papillaris, reduce bacterium and enter the mammary gland chance by ductus papillaris, and reduced the infection of recessive mastitis.
The use of organic trace element has improved absorption rate, has strengthened the function of ductus papillaris keratoprotein, has promoted the sealing of ductus papillaris, has reduced somatic number in the incidence of recessive mastitis and the milk.
The precious product of health breast can effectively prevent bacillary mammitis as a kind of milk cow special-purpose non-toxic feed addictive, strengthens the milk cow body immunity, significantly reduces body cell and improves the output of milk.
Biochemical fulvic acid can improve the output of milk and the dairy food quality of milk cow, reduces the incidence of disease of cow recessive mastitis, has preferably result for the treatment of for clinic mastitis, no drug residue, to the ox body stress not, safe and reliable.
But mould energy-absorbing effectively reduces mycotoxin to the infringement of animal body, strengthens the animal immune function, effectively reduces the incidence of milk cow miscarriage, stillborn foetus, improves the output of milk and milk-quality.
The functional additive products of four kinds of prevention recessive mastitis are added in above-mentioned evidence in the dairy cow diet, the incidence of reduction cow subclinical mastitis that can be has in various degree indirectly improved milk production of cow.Wherein, the additive group of the present invention of feeding is compared with control group, the duration of test output of milk on average improves 2.12kg, body cell average is than testing the front lower 22.93 ten thousand/ml that fallen in the milk, effect significantly is better than other experiment products, therefore, the effect of feed addictive prevention recessive mastitis of the present invention, reduction somatic number is remarkable, is worth promoting in practice.
Organic Selenium, organic zinc, the test of vitamin E synergistic function and biological anti-oxidant and reduction somatic number purpose feed addictive (the health breast is precious) synergistic function test
When functional additive of the present invention is carried out feeding experiment, we have carried out respectively testing and verification to Organic Selenium, organic zinc, vitamin E and biological anti-oxidant, reduction somatic number purpose feed addictive (the health breast is precious) synergistic function, and concrete process of the test and result are as follows:
1, test is processed
Each organizes basal diet, and to keep original daily ration level constant, and managerial skills are consistent, adds functional additive not of the same race, 60 days experimental periods respectively in each test group daily ration.Wherein, the precious group of health breast in the lower column split, biochemical fulvic acid group, comprehensive three groups have been carried out overtesting simultaneously in functional additive feeding experiment of the present invention, and have obtained test data, so no longer repeat in this test.
Table one: test disposition statistical form
2, test cows basic data
Table two: cows statistical reliability data table before the test
3, experimental result and analysis
3.1 the impact on the output of milk
Can be found out by table three and Fig. 7, behind each group test Cow-feeding different functionalities additive, the precious group of health breast, biochemical fulvic acid group, comprehensive two groups compare the per day output of milk of duration of test with control group and improve respectively 0.82kg/d head, 0.65kg/d head, 1.53kg/d head and 0.53kg/d head with comprehensive three groups; Organic Selenium group, organic zinc group, VE group are compared all not raisings of the per day output of milk with comprehensive one group with control group.Can prove thus, health breast is precious, biochemical fulvic acid and Organic Selenium, organic zinc, VE make up respectively to add and compare its each component and add separately extremely significantly to the lifting effect of the output of milk, also prove that the health breast is precious simultaneously, the two combination interpolation of biochemical fulvic acid and Organic Selenium, organic zinc, VE three make up interpolation and have respectively obvious synergistic effect.
Table three: the different tests date is respectively organized output of milk statistics (kg/d head)
3.2 the impact on somatic number in the milk
Can be found out behind the interpolation various combination additive, different-effect is arranged all in the dairy cow diet by table four and Fig. 8.Wherein body cell average ratio is tested the front lower 2.37 ten thousand/ml that fallen in comprehensive three groups of milk; Body cell average is than testing the front lower 1.17 ten thousand/ml that fallen in comprehensive two groups of milk; Body cell average is respectively than the 1.68 ten thousand/ml that raise before testing, 4.13 ten thousand/ml, 0.87 ten thousand/ml, 18.03 ten thousand/ml, 13.5 ten thousand/ml, 24.65 ten thousand/ml and 49.78 ten thousand/ml in comprehensive one group, the precious group of biochemical fulvic acid group, health breast, VE group, organic zinc group, Organic Selenium group and the control group milk.Can prove thus, health breast is precious, the two combination interpolation of biochemical fulvic acid and Organic Selenium, organic zinc, VE three make up to add and compare its each component and add separately more significantly to the reduction effect of body cell average in the milk, and the collaborative interpolation of different component all has respectively obvious synergistic effect.
Table four: the different tests date is respectively organized somatic number statistical form in the milk (104/milliliter)
Annotate: upper table indicates the expression significant difference of different letters
Claims (3)
1. functional milks ox feed additive that prevents cow subclinical mastitis, it is characterized in that, based on the gross mass of described additive, it comprises: Organic Selenium 2%~6%, organic zinc 2%~6%, biological anti-oxidant 4~8%, mould bacteria adsorbent 8%~12%, vitamin 0.2%~0.6%, conventional reduction somatic number purpose additive health breast treasured 8%~12%, surplus are carrier.
2. functional milks ox feed additive according to claim 1, it is characterized in that, described additive package contains reduction somatic number purpose additive 10%, vitamin 0.4%, the carrier 65.6% of Organic Selenium 4%, organic zinc 4%, biological anti-oxidant 6%, mould bacteria adsorbent 10%, routine.
3. functional milks ox feed additive according to claim 1 is characterized in that, described Organic Selenium is the happy selenium of match; Described organic zinc is hundred happy zinc; Described biological anti-oxidant is biochemical fulvic acid; Described mould bacteria adsorbent is mould the suction; Described vitamin is vitamin E; Described carrier is one of in time powder and the zeolite powder or combination.
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CN102499330B (en) * | 2011-12-28 | 2014-01-15 | 内蒙古伊利实业集团股份有限公司 | Feed additive for dairy cow |
CN102973923B (en) * | 2012-12-19 | 2014-06-18 | 上海光明荷斯坦牧业有限公司 | Compound premix for preventing and treating dairy cow mastitis recessive, and preparation method and application |
CN104012803B (en) * | 2014-06-12 | 2016-05-25 | 天津和正美科技发展有限公司 | A kind of preparation method of the fermented feed that can prevent mastitis for milk cows |
CN104304749B (en) * | 2014-10-10 | 2016-07-06 | 青岛嘉瑞生物技术有限公司 | A kind of improve milk production of cow, improve the Chinese herbal feed additive of milk quality |
CN104431362B (en) * | 2014-12-08 | 2017-09-19 | 湖南泰丰动物药业有限公司 | It is a kind of to improve the feed addictive and its application process of milk cow oxidative stress |
CN104351584B (en) * | 2014-12-08 | 2016-09-14 | 湖南泰丰动物药业有限公司 | A kind of feed additive reducing somatic number in milk and application thereof |
CN104784171B (en) * | 2015-02-16 | 2017-06-13 | 中国农业大学 | A kind of compound anti-oxidation preparation for reducing domestic animal somatic number and preparation method and application |
CN105851592A (en) * | 2016-05-30 | 2016-08-17 | 青岛海之源智能技术有限公司 | Sow mastitis feed additive with slow-release effect and preparation method |
CN110771743A (en) * | 2019-10-25 | 2020-02-11 | 曹文飞 | Feed capable of preventing dairy cow mastitis and preparation method thereof |
CN112741220A (en) * | 2019-10-30 | 2021-05-04 | 内蒙古伊利实业集团股份有限公司 | Compound feed additive for improving bad taste and smell of milk |
CN114431343A (en) * | 2020-11-06 | 2022-05-06 | 内蒙古伊利实业集团股份有限公司 | Compound feed additive, feed and application of compound feed additive |
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