CN109007344A - A kind of compound feed additive of anti-cow heat stress and preparation method thereof - Google Patents
A kind of compound feed additive of anti-cow heat stress and preparation method thereof Download PDFInfo
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- CN109007344A CN109007344A CN201811224403.9A CN201811224403A CN109007344A CN 109007344 A CN109007344 A CN 109007344A CN 201811224403 A CN201811224403 A CN 201811224403A CN 109007344 A CN109007344 A CN 109007344A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
- A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/174—Vitamins
Abstract
The invention discloses compound feed additives of a kind of anti-cow heat stress and preparation method thereof, the compound feed additive includes the raw material of following parts by weight: 10-20 parts of glossy privet fruit extract, 5-10 parts of siberian Ginseng P.E, 5-10 parts of probiotics, 10-20 parts of vitamin C, 5-10 parts of niacin, γ-aminobutyric acid 5-10 parts coated, α -1-5 parts of mannatide.Selected raw material of the present invention, cooperated using the extract of the fruit of glossy privet and wilsonii, energy strengthen immunity, improve the disease resistance of body, and cooperate vitamin C, niacin, the nutrition and health cares constituents such as γ-aminobutyric acid and α-mannatide, probiotics is added simultaneously, compatibility is reasonable between each ingredient, effect is complementary, preferable synergistic function can be generated, to improve animal immunizing power, enhance disease resistance, it is anti-oxidant, and the heat stress of milk cow can be prevented, it can also promote to digest and give milk, to animals and animal product noresidue after use, it has no toxic side effect, it is not likely to produce drug resistance.
Description
Technical field
The present invention relates to a kind of animal feed additives, and in particular to a kind of compound feed additive of anti-cow heat stress
And preparation method thereof.
Background technique
Heat stress refers to that body copes with the reaction of nonspecific response caused by warm and humid environment.Livestock and poultry are easily drawn by heat stress
Play its production performance immunity of organisms and product quality decline.The dairy bread of China's raising is mainly Holstein cow, is originated from
Cold Europe, its main feature is that production performance is good, the price of deed is high, but cold-resistant To Be Protected from Heat.Cow feeding amount when high temperature season,
Production performance, breeding and immunity degradation, disease incidence rises, or even can lead to the serious heatstroke of milk cow, thus it is dead, it is supported to milk cow
It grows industry and brings serious economic loss.Annual summer high temperature weather will cause southern area and milk cow heat occurs to some extent
Stress reaction drastically influences milk cow health and production.It has been reported that, annual heat stress can reduce southern area milk crop ten thousand
Ton or more, thus the fast development of southern area milk cow production must effectively solve the problems, such as heat stress.
Currently, the feed addictive for anti heat stress for milk cow is chemical synthesis substance mostly, it is easy to produce medicament residue
And toxic side effect, endanger human health.Chinese herbal feed additive has many kinds of, vdiverse in function, matching medication effect more
It is good, derived from nature, use scope it is wide, it is at low cost have no drug resistance, noresidue, Small side effects, it is free from environmental pollution, do not cause drug induccd
The advantages that disease.Under the requirement that " environmentally protective, ecological efficient " is pursued by the world today, anti-cow heat stress Chinese herbal feed adds
Agent is added to have broad prospects.
But due to it is most of it is used be herb mixture and powder, prescription is complicated and the processing is simple, invalid components mistake
It is cause palatability is poor, targeting is indefinite to keep effect slower more, and additive amount is big, so that the development of Chinese herb feed additive is by office
Limit；With the application of the single plants extract such as astragalus polyose and allicin, people increasingly have a profound understanding of Chinese medical extract
Target relative to mixture powder is bright and clear, easy the features such as absorbing, is quick, and people have found Chinese herbal medicine application in aquaculture
Another new way-extract；The development of purifying process technologies are processed along with various extractions, in addition the application of biological new technology,
Occur the product of more new class in the market --- the technical issues of extract complex additive and the present invention research and solve.
Summary of the invention
In view of the deficiencies of the prior art, the object of the present invention is to provide it is a kind of can alleviate Dairy Cows In Summer heat stress, enhancing exempt from
Epidemic disease power, the safety for improving production performance Chinese herbal medicine extract compound feed additive and preparation method thereof without any side effects.
To achieve the goals above, the technical scheme adopted by the invention is that:
A kind of compound feed additive of anti-cow heat stress, the raw material including following parts by weight: glossy privet fruit extract 10-
20 parts, 5-10 parts of siberian Ginseng P.E, 5-10 parts of probiotics, 10-20 parts of vitamin C, 5-10 parts of niacin, coated gamma-amino
5-10 parts of butyric acid, α -1-5 parts of mannatide.
Glossy privet fruit extract the preparation method comprises the following steps: the fruit of glossy privet is placed in 100 DEG C of boiling water of 3 times of weight impregnate 15min after,
Filtering is added the ethyl alcohol of 15 times of fruit of glossy privet weight of 70% (v/v), homogenate extraction 3min, then soak and extracting solution is mixed,
Extra water and ethyl alcohol are distilled with Rotary Evaporators, finally dry, crushing.
Siberian Ginseng P.E the preparation method comprises the following steps: wilsonii is placed in 100 DEG C of boiling water of 4 times of weight impregnate 15min after,
Filtering is added the ethyl alcohol of 13 times of wilsonii weight of 80% (v/v), homogenate extraction 3min, then soak and extracting solution is mixed,
Extra water and ethyl alcohol are distilled with Rotary Evaporators, finally dry, crushing.
Probiotics is bacillus subtilis, total viable count 109cfu/g。
Coated γ-aminobutyric acid includes the raw material of following weight percent: 50% γ-aminobutyric acid, 28% jade
Rice starch, 10% hypromellose, 9.5% tristerin, 2.5% polyacrylic resinⅡ；It is prepared
A method are as follows: using γ-aminobutyric acid as core material, other raw materials are wall material, and first the γ-aminobutyric acid of powdery is made with granulator
It is granular, then remaining raw material is mixed, fluidized bed plant is sprayed the bottom of using, in 20 DEG C of inlet air temperature, 42 DEG C of leaving air temp, oil temperature 75
γ-aminobutyric acid is coated under conditions of DEG C, coated γ-aminobutyric acid is made.
A kind of preparation method of the compound feed additive of anti-cow heat stress, each raw material is mixed to obtain the final product.
A kind of application method of the compound feed additive of anti-cow heat stress, adds concentrate supplement in milk cow forage
The compound feed additive of weight 1-4%.
The fruit of glossy privet: the fruit of glossy privet contains a variety of active ingredients, can effectively improve the production performance, immune function and antioxygen of animal
Change ability.
Wilsonii: main active is that general glycoside and polysaccharide have in addition there are also isofraxidin, flavones and organic acid etc.
Enhance the functions such as body's immunity, anti-oxidant, antibacterial, antiviral, antifatigue and adjusting gastrointestinal tract pH value.
Probiotics: rumen microorganism flora when heat stress can be made to keep balance, normal digestive function is maintained, improve production
Performance.
Vitamin C: can enhance human body immune function, improve anti-stress ability, directly participation cell and immune response,
It effectively removes under stressed condition and generates living radical.
Niacin: the metabolism of three big organic substances is participated in, can be relieved various stress factors.
γ-aminobutyric acid: for central nervous system impression nerve mediator, there is sedation, while some rush can be activated
Immune subtype peptide can promote feeding, alleviate physiological responses to heat stress.
α-mannatide: can promote activated immune cell proliferation and specific antibody to generate, improve peripheral white blood cell,
Animal is significantly increased to the emergency function of various environment；With special antibacterial effect, adsorbs and inhibit pathogenic bacteria in enteron aisle
Field planting and growth promote beneficial bacterium proliferation in enteron aisle.
Compared with prior art, the invention has the following advantages that
(1) selected raw material of the present invention is cooperated using the extract of the fruit of glossy privet and wilsonii, can strengthen immunity, raising machine
The disease resistance of body, and cooperate the nutrition and health cares constituents such as vitamin C, niacin, γ-aminobutyric acid and α-mannatide, together
Shi Tianjia probiotics, compatibility is reasonable between each ingredient, and effect is complementary, can generate preferable synergistic function, to improve dynamic
Object immunity enhances disease resistance, anti-oxidant, and can prevent the heat stress of milk cow, moreover it is possible to promote digestion and milk production, it is right after use
Animals and animal product noresidue has no toxic side effect, and is not likely to produce drug resistance.
(2) present invention applies the extract of the fruit of glossy privet and wilsonii, has safe and free of toxic and side effects, additive amount few etc. excellent
Point, and targeting is clear when acting in animal body.
(3) feed addictive of the present invention, green, safety, ecological, environmental protective can not only improve immunity, and can improve feeding
The production efficiency of material reduces feeding cost, has preferable society and economic value.
Specific embodiment
Specific embodiments of the present invention will be described in further detail with reference to embodiments.
Glossy privet fruit extract the preparation method comprises the following steps: the fruit of glossy privet is placed in 100 DEG C of boiling water of 3 times of weight impregnate 15min after,
Filtering is added the ethyl alcohol of 15 times of fruit of glossy privet weight of 70% (v/v), homogenate extraction 3min, then soak and extracting solution is mixed,
Extra water and ethyl alcohol are distilled with Rotary Evaporators, finally dry, crushing.
Siberian Ginseng P.E the preparation method comprises the following steps: wilsonii is placed in 100 DEG C of boiling water of 4 times of weight impregnate 15min after,
Filtering is added the ethyl alcohol of 13 times of wilsonii weight of 80% (v/v), homogenate extraction 3min, then soak and extracting solution is mixed,
Extra water and ethyl alcohol are distilled with Rotary Evaporators, finally dry, crushing.
Coated γ-aminobutyric acid includes the raw material of following weight percent: 50% γ-aminobutyric acid, 28% jade
Rice starch, 10% hypromellose, 9.5% tristerin, 2.5% polyacrylic resinⅡ；It is prepared
Method are as follows: using γ-aminobutyric acid as core material, other raw materials are wall material, first the γ-aminobutyric acid granulator (die hole of powdery
Diameter 1.0mm) graininess is made, then remaining raw material is mixed, fluidized bed plant is sprayed the bottom of using, in 20 DEG C of inlet air temperature, is gone out
42 DEG C of air temperature is coated γ-aminobutyric acid under conditions of 75 DEG C of oil temperature, and coated γ-aminobutyric acid is made.
Embodiment 1
A kind of compound feed additive of anti-cow heat stress, which is characterized in that the raw material including following parts by weight: glossy privet
20 parts of seed extract, 10 parts of siberian Ginseng P.E, bacillus subtilis (total viable count 109Cfu/g) 10 parts, vitamin C 20
Part, 10 parts of niacin, 10 parts of coated γ-aminobutyric acid, 5 parts of α-mannatide.
Preparation method are as follows: mix each raw material to obtain the final product.
Embodiment 2
A kind of compound feed additive of anti-cow heat stress, which is characterized in that the raw material including following parts by weight: glossy privet
15 parts of seed extract, 7 parts of siberian Ginseng P.E, bacillus subtilis (total viable count 109Cfu/g) 7 parts, 15 parts of vitamin C,
8 parts of niacin, 7 parts of coated γ-aminobutyric acid, 3 parts of α-mannatide.
Preparation method are as follows: mix each raw material to obtain the final product.
Embodiment 3
A kind of compound feed additive of anti-cow heat stress, which is characterized in that the raw material including following parts by weight: glossy privet
10 parts of seed extract, 5 parts of siberian Ginseng P.E, bacillus subtilis (total viable count 109Cfu/g) 5 parts, 10 parts of vitamin C,
5 parts of niacin, 5 parts of coated γ-aminobutyric acid, 1 part of α-mannatide.
Preparation method are as follows: mix each raw material to obtain the final product.
Comparative test
It is tested under the conditions of heat stress, 32-40 DEG C of temperature, relative humidity 72-79%.Choose weight, age, tire
Secondary, the output of milk is close and without mammitis holstein cow 40 are divided into four groups, every group 10.One group is control group, and feeding is normal
Daily ration is advised, in addition three groups are respectively 1,2,3 group of test, respectively feeding addition feed addictive (embodiment 1) of the present invention, wilsonii
The daily ration of extract and Honegsukle flower P.E (the same siberian Ginseng P.E of preparation method), additive amount are the essence added in milk cow forage
The 1% of material supplement material weight.Preliminary trial period 7 days, experimental period 35 days.Experimental period, measures weekly an output of milk, and collects milk sample, surveys
Fixed test front and back milk composition.Test mid-term, at the end of acquire the tail vein 10mL of every cow head, after 4000r/min is centrifuged 15min
Separate serum, freezen protective.Measure serum in thyroxine (T4), triiodo thryonine (T3), glutamic-pyruvic transaminase (ALT),
Glutamic-oxalacetic transaminease (AST), alkaline phosphatase (ALP) etc..
Influence (kg/d) of 1 complex additive of table to heat stress phase milk production of cow
Influence (g/100mL) of 2 complex additive of table to heat stress phase milk cow production performance and milk composition
When milk cow is in heat stress it can be seen from table 1, table 2, the control group output of milk is in experimental stage due to heat stress original
Because slowly declining；And three test groups declined before 15 days since heat stress is first slow, but after 15 days since drug effect plays
Effect, output of milk bottom out, wherein 2 groups of test gone up but and be less than the output of milk of incipient stage, test 1,3 group
The output of milk for ging up and be more than the incipient stage, is respectively increased 7.2% and 2.8%；Lactose, the cream of three test groups and control group
Rouge, lactoprotein are without significant difference (P > 0.05).It can be seen that test 1-3 group adds additive to milk cow in dairy cow diet
Milk-quality there is no adverse effect, but all have alleviate heat stress and enhance dairy cattle, improve milk yield effect, examination
It is best to test 1 group of effect.
Influence of 3 complex additive of table to heat stress phase cow serum biochemical indicator
Note: colleague's data shoulder mark difference lowercase letter indication difference is significant (P < 0.05), and shoulder mark difference capitalization indicates
Difference is extremely significant (P<0.01), and shoulder mark is identical or not marking indicates difference not significantly (P>0.05).
As shown in Table 3, when feed addictive of the invention is contained to Cow-feeding, siberian Ginseng P.E and honeysuckle are extracted
Glutamic-pyruvic transaminase (ALT), glutamic-oxalacetic transaminease (AST) content decrease than control group in each test group serum after object, difference
Significantly (P < 0.05), and test 1 group and be substantially less than 2,3 groups of test；Three test group of alkaline phosphatase (ALP) content is significant low
In control group (P < 0.05), and tests 1 group and be substantially less than 2,3 groups of test；Triiodo thryonine (T3), thyroxine (T4)
Content control group increased, significant difference (P < 0.05), and tests 1 group and be significantly higher than 2,3 groups of test.
It can be seen that heat stress milk can be made by adding anti-heat stress compounding agent and other two kinds of additives in dairy cow diet
Glutamic-pyruvic transaminase (ALT), glutamic-oxalacetic transaminease (AST), alkaline phosphatase (ALP) content reduce in cow's serum, thyroxine (T4),
Triiodo thryonine (T3) content increases, to alleviate influence of the heat stress to milk cow, but most aobvious with the effect for testing 1 group
It writes.
The foregoing is merely the optimal embodiments of the present invention, and for those skilled in the art, the present invention can have
Various modifications and variations.All within the spirits and principles of the present invention, any modification, equivalent replacement, improvement and so on, should all
It is included within protection scope of the present invention.
Claims (7)
1. a kind of compound feed additive of anti-cow heat stress, which is characterized in that the raw material including following parts by weight: the fruit of glossy privet
10-20 parts of extract, 5-10 parts of siberian Ginseng P.E, 5-10 parts of probiotics, 10-20 parts of vitamin C, 5-10 parts of niacin, coating
5-10 parts of γ-aminobutyric acid, α -1-5 parts of mannatide.
2. the compound feed additive of anti-cow heat stress according to claim 1, which is characterized in that the fruit of glossy privet
Extract the preparation method comprises the following steps: the fruit of glossy privet is placed in 100 DEG C of boiling water of 3 times of weight impregnate 15min after, filtering, be added glossy privet
The ethyl alcohol of 70% (v/v) of 15 times of sub- weight, homogenate extraction 3min, then soak and extracting solution are mixed, use Rotary Evaporators
Extra water and ethyl alcohol are distilled, finally dry, crushing.
3. the compound feed additive of anti-cow heat stress according to claim 1, which is characterized in that the wilsonii
Extract the preparation method comprises the following steps: wilsonii is placed in 100 DEG C of boiling water of 4 times of weight impregnate 15min after, filtering, be added thorn five
The ethyl alcohol of 13 times of add weight of 80% (v/v), homogenate extraction 3min, then soak and extracting solution are mixed, use Rotary Evaporators
Extra water and ethyl alcohol are distilled, finally dry, crushing.
4. the compound feed additive of anti-cow heat stress according to claim 1, which is characterized in that the probiotics
For bacillus subtilis, total viable count 109cfu/g。
5. the compound feed additive of anti-cow heat stress according to claim 1, which is characterized in that described is coated
γ-aminobutyric acid includes the raw material of following weight percent: 50% γ-aminobutyric acid, 28% cornstarch, 10% hydroxyl
Third methylcellulose, 9.5% tristerin, 2.5% polyacrylic resinⅡ；Preparation method are as follows: with gamma-amino
Butyric acid is core material, and other raw materials are wall material, graininess first is made with granulator in the γ-aminobutyric acid of powdery, then by remaining
Raw material mixing sprays fluidized bed plant the bottom of using, to γ-under conditions of 20 DEG C of inlet air temperature, 42 DEG C of leaving air temp, 75 DEG C of oil temperature
Aminobutyric acid is coated, and coated γ-aminobutyric acid is made.
6. a kind of preparation method of the compound feed additive of anti-cow heat stress as described in any one in claim 1-5,
It is characterized in that, each raw material is mixed to obtain the final product.
7. a kind of application method of the compound feed additive of anti-cow heat stress as described in any one in claim 1-5,
It is characterized in that, the compound feed additive of concentrate supplement weight 1-4% is added in milk cow forage.
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| CN201811224403.9A CN109007344A (en) | 2018-10-19 | 2018-10-19 | A kind of compound feed additive of anti-cow heat stress and preparation method thereof |
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| CN201811224403.9A CN109007344A (en) | 2018-10-19 | 2018-10-19 | A kind of compound feed additive of anti-cow heat stress and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109892476A (en) * | 2019-03-28 | 2019-06-18 | 江苏波杜农牧股份有限公司 | A kind of milch goat full-valence pellet feed containing glossy privet fruit extract |
| CN115176871A (en) * | 2022-06-29 | 2022-10-14 | 瑞普高科(天津)生物技术有限公司 | Anti-stress antioxidant feed additive and preparation method and application thereof |
| CN116195688A (en) * | 2023-03-16 | 2023-06-02 | 宁夏大学 | Functional feed additive for dairy cows, feed and preparation method |
-
2018
- 2018-10-19 CN CN201811224403.9A patent/CN109007344A/en active Pending
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| 李崇婕: "防重于治_抗应激调节免疫之优品", 《中国动物保健》 * |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109892476A (en) * | 2019-03-28 | 2019-06-18 | 江苏波杜农牧股份有限公司 | A kind of milch goat full-valence pellet feed containing glossy privet fruit extract |
| CN115176871A (en) * | 2022-06-29 | 2022-10-14 | 瑞普高科(天津)生物技术有限公司 | Anti-stress antioxidant feed additive and preparation method and application thereof |
| CN116195688A (en) * | 2023-03-16 | 2023-06-02 | 宁夏大学 | Functional feed additive for dairy cows, feed and preparation method |
| CN116195688B (en) * | 2023-03-16 | 2024-02-13 | 宁夏大学 | Functional feed additive for dairy cows, feed and preparation method |
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Application publication date: 20181218 |