CN102106937A - Medicament for treating psoriasis - Google Patents

Abstract

The invention discloses a medicament for treating psoriasis, which is prepared by the steps of uniformly mixing raw radix rehmanniae, Chinese angelica, szechuan lovage rhizome, white paeony root, honeysuckle, red paeony root, red flower, peach seed, periostracum cicadae, lightyellow sophora root, white ringworm skin, isatis root, common ducksmeat herb, sophora flower, cornu bubali, turtle shell, tortoise plastron, long-noded pit viper and tail snake; crushing the medicines into medicinal powder of 100-120 meshes; and according to a conventional method, adding honey to the medicinal powder, forming, sterilizing and disinfecting to obtain pill products. The medicament disclosed by the invention has the effects on nourishing both yin and kidney, cooling blood, dissipating blood stasis, dispelling wind and relieving itching, can be used for treating psoriasis, and has the characteristics of quick effect taking, small side effects and no relapse. Through clinical observation, the effective rate of the medicament is 100%.

Description

A kind ofly be used for the treatment of psoriatic medicine

Technical field

The present invention relates to the psoriatic medicine of a kind of treatment, particularly relating to a kind of is the psoriatic Chinese medicine of treatment of crude drug preparation with Chinese medicine.

Background technology

Psoriasis has another name called psoriasis, is a kind of common erythema unicorn bits property chronic inflammatory disease dermatoses.Psoriasis shows effect repeatedly, and its skin lesion can general whole body, is more common in head, extremity are stretched face, the back, and skin lesion shows as the pale red maculopapule, with the normal skin clear-cut margin, surface coverage has silvery white squama, scrapes off squama, can expose semi-transparent film, scrape off the visible little petechia of this film, illing skin has pruritus in various degree, and men and women, old and young all can fall ill, and is a kind of skin class difficult miscellaneous diseases.At present, clinically this sick Therapeutic Method is adopted external medication mostly, as glucocorticoid, tretinoin cream etc., but side effect is big, can not effect a radical cure, easily repeatedly.

Summary of the invention

The purpose of this invention is to provide a kind of psoriatic medicine that is used for the treatment of, this medicine is made up of Chinese medicine and is had enriching yin and nourishing kidney, cooling blood and removing stasis, and wind dispelling itching relieving effect can play instant effect to psoriatic treatment, and side effect is little, is difficult for the purpose of recurrence.

Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:

Radix Rehmanniae 9～11 Radix Angelicae Sinensis 4～6

Rhizoma Chuanxiong 4～6 Radix Paeoniae Albas 4～6

Flos Lonicerae 4～6 Radix Paeoniae Rubra 4～6

Flos Carthami 4～6 Semen Persicaes 4～6

Periostracum Cicadae 4～6 Radix Sophorae Flavescentiss 4～6

Favus skin 4～6 Radix Isatidis 4～6

Herba Spirodelae 4～6 Flos Sophoraes 4～6

Cornu Bubali 5～7 Carapax Trionycis 5～7

Carapax et Plastrum Testudinis 5～7 Agkistrodons 1～3

Zaocys 5～7.

Said medicine can be made any dosage form on the pharmaceutics, as tablet, pill, powder, capsule etc., the preferred dosage form of the present invention is a pill.

The concrete preparation method of medicine of the present invention being made pill is:

Said medicine by described parts by weight mix homogeneously, is ground into 100～120 purpose medicated powder, adds sweet molding, molding according to conventional method medicated powder, sterilization makes the pill product.

The traditional Chinese medical science is thought psoriatic pathogenesis at blood, and endogenous cause of ill mostly is damaged by excess of seven emotions, or eating and drinking without temperance, have a liking for food delicious food savoury etc., so that aquatic weeds heat is in blood; Exopathogenic factor mostly is to experience ailment said due to cold or exposure or hold under the arm and scorchingly injures skin and fall ill.The Therapeutic Principle is enriching yin and nourishing kidney, cooling blood and removing stasis, and wind dispelling is antipruritic.Radix Rehmanniae, Radix Angelicae Sinensis nourishing YIN and supplementing blood; Radix Paeoniae Alba nourishing blood to suppress the hyperactive liver; Rhizoma Chuanxiong blood circulation promoting and blood stasis dispelling, wind-expelling pain-stopping; The Radix Sophorae Flavescentis heat clearing and damp drying; Favus skin heat clearing and damp drying, the detoxifcation of dispeling the wind; Radix Isatidis, Herba Spirodelae heat-clearing and toxic substances removing; The heat clearing away sophora removing heat from blood; The Periostracum Cicadae wind heat extraction that looses; Radix Paeoniae Rubra clearing away heat and cooling blood, eliminating stasis to stop pain; Cornu Bubali clearing away heat and cooling blood, detoxifcation; Semen Persicae, Flos Carthami blood circulation promoting and blood stasis dispelling; Carapax Trionycis, Carapax et Plastrum Testudinis nourishing YIN and clearing away heat; Agkistrodon, Zaocys wind dispelling collateral dredging, expelling pathogenic factors from the exterior are antipruritic.All medicines share, enriching yin and nourishing kidney, and cooling blood and removing stasis, wind dispelling is antipruritic, is used for psoriatic treatment, has instant effect, little, the difficult characteristics that recur of side effect.

For further investigating the clinical efficacy and the safety of medicine of the present invention, select 94 routine psoriatics that the curative effect of medicine of the present invention has been carried out clinical observation.

94 routine cases are divided into two groups at random, and 64 people are organized in treatment, matched group 30 people.All case is diagnosed as psoriasis all according to the diagnostic criteria of " new Chinese medicine clinical research guideline (the 3rd volume) ".

Therapeutic Method

Matched group adopts fangfeng tongsheng pill (big honeyed pills), takes each 1 ball every day 2 times; The noxious dampness clearing capsule is taken 3 every day, one time 3.The treatment group adopts the pill of medicine of the present invention to treat, and takes each 1 ball every day 3 times.40 days is a course of treatment, takes 2 courses of treatment altogether.

Criterion of therapeutical effect

Criterion of therapeutical effect is with reference to " new Chinese medicine clinical research guideline (the 3rd volume) ", and recovery from illness: skin lesion all disappears, or only residual several unconspicuous fritter skin lesion.Effectively: skin lesion disappears more than 30%.Invalid: skin lesion disappears below 30%, or skin lesion no change or skin lesion increase the weight of.

Two groups of case treatment back curative effect comparative results see Table 1.

Table 1 liang group case treatment back curative effect relatively

Group	The example number	Recovery from illness n(%)	Effective n(%)	Invalid n(%)	Total effective rate n(%)
						Matched group	30	21（70）	6（20）	3（10）	27（90）
The treatment group	64	56（87.5）	8（12.5）	0（0）	64（100）

Statistical result showed, treatment group curative effect obviously is better than matched group, and two group differences are remarkable, P＜0.05.

The specific embodiment

Embodiment 1

Get Radix Rehmanniae 100g selected, that clear water is cleaned, Radix Angelicae Sinensis 50g, Rhizoma Chuanxiong 50g, Radix Paeoniae Alba 50g, Flos Lonicerae 50g, Radix Paeoniae Rubra 50g, Flos Carthami 50g, Semen Persicae 50g, Periostracum Cicadae 50g, Radix Sophorae Flavescentis 50g, favus skin 50g, Radix Isatidis 50g, Herba Spirodelae 50g, Flos Sophorae 50g, Cornu Bubali 60g Carapax Trionycis 60g, Carapax et Plastrum Testudinis 60g, Agkistrodon 15g, Zaocys 60g mix homogeneously, be ground into 100～120 purpose medicated powder, medicated powder adds sweet molding, molding, and sterilization makes the pill product.

Embodiment 2

Get the Radix Rehmanniae selected, that clear water is cleaned 90 grams, Radix Angelicae Sinensis 45g, Rhizoma Chuanxiong 50g, Radix Paeoniae Alba 55g, Flos Lonicerae 40g, Radix Paeoniae Rubra 50g, Flos Carthami 50g, Semen Persicae 60g, Periostracum Cicadae 50g, Radix Sophorae Flavescentis 50g, favus skin 50g, Radix Isatidis 45g, Herba Spirodelae 50g, Flos Sophorae 50g, Cornu Bubali 55g, Carapax Trionycis 60g, Carapax et Plastrum Testudinis 50g, Agkistrodon 15g, Zaocys 50g mix homogeneously, be ground into 100～120 purpose medicated powder, medicated powder adds sweet molding, molding, and sterilization makes the pill product.

Claims (2)

1. one kind is used for the treatment of psoriatic medicine, is that the Chinese medicine by following portions by weight is that crude drug prepares:

Radix Rehmanniae 9～11 Radix Angelicae Sinensis 4～6

Rhizoma Chuanxiong 4～6 Radix Paeoniae Albas 4～6

Flos Lonicerae 4～6 Radix Paeoniae Rubra 4～6

Flos Carthami 4～6 Semen Persicaes 4～6

Periostracum Cicadae 4～6 Radix Sophorae Flavescentiss 4～6

Favus skin 4～6 Radix Isatidis 4～6

Herba Spirodelae 4～6 Flos Sophoraes 4～6

Cornu Bubali 5～7 Carapax Trionycis 5～7

Carapax et Plastrum Testudinis 5～7 Agkistrodons 1～3

Zaocys 5～7.

2. according to claim 1ly be used for the treatment of psoriatic medicine, it is characterized in that described medicine is made pill.