Rheumatoid arthritis Ramulus Mori Radix Rehmanniae Chinese medicine oral liquid and method for preparing
Technical field
The invention belongs to the field of Chinese medicines, particularly a kind of rheumatoid arthritis Ramulus Mori Radix Rehmanniae Chinese medicine oral liquid and method for preparing.
Background technology
Rheumatoid arthritis (RA) is mainly to show as symmetric multi-joint chronic inflammation disease on every side, be a kind of be master's autoimmune disease with the chronic progressive external arthropathy, wrist, elbow, knee joint, ankle and joints of foot Chang Yi are symmetry and get involved.Infection and autoimmune response are the key links of RA morbidity and state of an illness delay, and endocrine, heredity and environmental factors etc. have then increased the susceptibility of RA.Theory of Chinese medical science is thought: positive QI-insufficiency, and caused by liver and kidney deficiency, muscles and bones is not strong, and interspaces of skin and muscles being loose, weakened defensive QI are the intrinsic factor that cause RA; Exopathogenic factor is the damp and hot heresy invasion and attack of wind and cold.Disease is prone to into network for a long time, and causes blood stasis resistance network, thus wind, wet, heat, tremble with fear, the stasis of blood, void be its main pathological factor.Chinese medicine is used to treat the medicine of rheumatoid arthritis, owing to have little, the eutherapeutic characteristics of side effect, so favored by people.
Summary of the invention
The object of the present invention is to provide little, the good effect of a kind of side effect, be used for rheumatoid arthritis Ramulus Mori Radix Rehmanniae Chinese medicine oral liquid and method for preparing.
For realizing above-mentioned purpose, the present invention realizes through following technical scheme:
Rheumatoid arthritis Ramulus Mori Radix Rehmanniae Chinese medicine oral liquid is to be processed by the crude drug of following parts by weight:
Radix Gentianae Macrophyllae 50-150 part, Radix Stephaniae Tetrandrae 50-150 part, Herba Taxilli 50-150 part, Ramulus Mori 200-400 part, Radix Rehmanniae 200-400 part, Semen pini koraiensis 50-150 part, Caulis Lonicerae 50-150 part.
Described rheumatoid arthritis Ramulus Mori Radix Rehmanniae Chinese medicine oral liquid is to be processed by the crude drug of following parts by weight:
100 parts of Radix Gentianae Macrophyllae, 100 parts of Radixs Stephaniae Tetrandrae, 100 parts of Herba Taxillis, 300 parts of Ramulus Moris, 300 parts in the Radix Rehmanniae, 100 parts of Semen pini koraiensis, 100 parts of Caulis Loniceraes.
Described rheumatoid arthritis Ramulus Mori Radix Rehmanniae Chinese medicine oral liquid and method for preparing comprise the following steps:
Get it filled 100 parts of material Radix Gentianae Macrophyllae, 100 parts of Radixs Stephaniae Tetrandrae, 100 parts of Herba Taxillis, 300 parts of Ramulus Moris, 300 parts in the Radix Rehmanniae, 100 parts of Semen pini koraiensis, 100 parts of Caulis Loniceraes, water decocts secondary, and the 8-10 that each water consumption is a medical material weight doubly measures, and decocts secondary; Each 1-2 hour, filter, filtrating is condensed into and surveys relative density at 60-65 ℃ is the clear paste of 1.10-1.25, to contain amount of alcohol be 60% to making to add ethanol; Stir, leave standstill, filter, get filtrate recycling ethanol; Be condensed into the extractum that contains solid weight 65-67%, add sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, irradiation sterilization; Packed products is processed oral liquid, promptly gets.
Instructions of taking: every day early, middle and late respectively taking once, a dose is 20ml, 30 days is a course of treatment, takes medicine that the back is many took effect at 5 days, 3-6 the healing course of treatment.This Chinese medicine oral liquid characteristics are that the patient is fully recovered is effective, and toxic and side effects is little, play treating both the principal and secondary aspects of a disease, set upright evil, the eliminating evil positive effect of not hindering that do not stagnate, and do not have recurrence, and cost is low, is worth clinical application.
In the raw material of Chinese medicine that the present invention selected for use, Radix Gentianae Macrophyllae: bitter, hot, be slightly cold, return stomach, liver, gallbladder meridian, wind-damp dispelling, channels sootheing and network vessel quickening, clearind deficient heat; Radix Stephaniae Tetrandrae: bitter, hot, cold, return bladder, kidney, spleen channel, wind-damp dispelling, pain relieving, diuretic; Herba Taxilli: bitter, sweet, flat, return liver, kidney channel, wind-damp dispelling, liver and kidney tonifying, bone and muscle strengthening, antiabortive; Ramulus Mori: little hardship, flat, return Liver Channel, wind-damp dispelling, sharp joint, be used to take on arm, joint aches is numb; The Radix Rehmanniae: sweet, bitter, cold, GUIXIN, liver, kidney channel, clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting; Semen pini koraiensis: sweet, tepor, return liver, lung, large intestine channel, moisturize, nourish blood, dispel the wind; Caulis Lonicerae: cold, sweet, flat, attach to the lung and stomach meridians heat-clearing and toxic substances removing, dispelling wind collateral dredging.Theory of Chinese medical science is thought: positive QI-insufficiency, and caused by liver and kidney deficiency, muscles and bones is not strong, and interspaces of skin and muscles being loose, weakened defensive QI are the intrinsic factor that cause rheumatoid arthritis; Exopathogenic factor is the damp and hot heresy invasion and attack of wind and cold.Disease is prone to into network for a long time, and causes blood stasis resistance network, thus wind, wet, heat, tremble with fear, the stasis of blood, void be its main pathological factor.The catabasis eliminating pathogenic factor for supporting vital QI is the rule of treatment; We are method of treatment with expelling wind and removing dampness heat clearing away cold expelling, liver and kidney tonifying, benefiting qi and nourishing blood, blood circulation promoting and blood stasis dispelling, inducing diuresis to remove edema, removing obstruction in the collateral to relieve pain; All medicines share, and play expelling wind and removing dampness, clearing heat for detumescence, cold expelling collateral dredging, relaxing muscles and tendons to promote blood circulation altogether, fill blood, the merit of liver and kidney tonifying, eliminating impediment pain relieving.Oral liquid of the present invention can effectively be removed the symptom of the arthralgia due to the rheumatoid arthritis, and specially medicine is specially controlled, and is evident in efficacy.Points for attention: anemia of pregnant woman's forbidding.
The specific embodiment
EXAMPLE l:
Crude drug: 100 parts of Radix Gentianae Macrophyllae, 100 parts of Radixs Stephaniae Tetrandrae, 100 parts of Herba Taxillis, 300 parts of Ramulus Moris, 300 parts in the Radix Rehmanniae, 100 parts of Semen pini koraiensis, 100 parts of Caulis Loniceraes.
Method for making: 100 parts of the material Radix Gentianae Macrophyllae of getting it filled, 100 parts of Radixs Stephaniae Tetrandrae, 100 parts of Herba Taxillis, 300 parts of Ramulus Moris, 300 parts in the Radix Rehmanniae, 100 parts of Semen pini koraiensis, 100 parts of Caulis Loniceraes, water decocts secondary, and the 8-10 that each water consumption is a medical material weight doubly measures, and decocts secondary; Each 1-2 hour, filter, filtrating is condensed into and surveys relative density at 60-65 ℃ is the clear paste of 1.10-1.25, to contain amount of alcohol be 60% to making to add ethanol; Stir, leave standstill, filter, get filtrate recycling ethanol; Be condensed into the extractum that contains solid weight 65-67%, add sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, irradiation sterilization; Packed products is processed oral liquid, promptly gets.
Embodiment 2:
Crude drug: 150 parts of Radix Gentianae Macrophyllae, 150 parts of Radixs Stephaniae Tetrandrae, 150 parts of Herba Taxillis, 400 parts of Ramulus Moris, 400 parts in the Radix Rehmanniae, 150 parts of Semen pini koraiensis, 150 parts of Caulis Loniceraes.
Method for making: 150 parts of the material Radix Gentianae Macrophyllae of getting it filled, 150 parts of Radixs Stephaniae Tetrandrae, 150 parts of Herba Taxillis, 400 parts of Ramulus Moris, 400 parts in the Radix Rehmanniae, 150 parts of Semen pini koraiensis, 150 parts of Caulis Loniceraes, water decocts secondary, and the 8-10 that each water consumption is a medical material weight doubly measures, and decocts secondary; Each 1-2 hour, filter, filtrating is condensed into and surveys relative density at 60-65 ℃ is the clear paste of 1.10-1.25, to contain amount of alcohol be 60% to making to add ethanol; Stir, leave standstill, filter, get filtrate recycling ethanol; Be condensed into the extractum that contains solid weight 65-67%, add sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, irradiation sterilization; Packed products is processed oral liquid, promptly gets.
Embodiment 3:
Crude drug: 50 parts of Radix Gentianae Macrophyllae, 50 parts of Radixs Stephaniae Tetrandrae, 50 parts of Herba Taxillis, 200 parts of Ramulus Moris, 200 parts in the Radix Rehmanniae, 50 parts of Semen pini koraiensis, 50 parts of Caulis Loniceraes.
Method for making: 50 parts of the material Radix Gentianae Macrophyllae of getting it filled, 50 parts of Radixs Stephaniae Tetrandrae, 50 parts of Herba Taxillis, 200 parts of Ramulus Moris, 200 parts in the Radix Rehmanniae, 50 parts of Semen pini koraiensis, 50 parts of Caulis Loniceraes, water decocts secondary, and the 8-10 that each water consumption is a medical material weight doubly measures, and decocts secondary; Each 1-2 hour, filter, filtrating is condensed into and surveys relative density at 60-65 ℃ is the clear paste of 1.10-1.25, to contain amount of alcohol be 60% to making to add ethanol; Stir, leave standstill, filter, get filtrate recycling ethanol; Be condensed into the extractum that contains solid weight 65-67%, add sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, irradiation sterilization; Packed products is processed oral liquid, promptly gets.
Embodiment 4:
1, clinical trial: 65 routine rheumatoid arthritis patients are carried out clinical observation alleviate, the age 30 is by 75 years old, the course of disease 1 year 1 years.
2, Therapeutic Method: take the made Chinese medicine oral liquid of embodiment of the invention l, every day early, middle and late respectively taking once, a dose is 20ml, 30 days is a course of treatment.
3, treatment standard:
Cure in the recent period: arthralgia and swelling disappear, and moving obstacle and both hands grip return to normal basically.
Produce effects: arthralgia and swelling disappear, and moving obstacle and both hands grip are recovered to have clear improvement.
Effectively: patient's self evaluation has improvement, the joint sx of getting involved.
Invalid: symptom no change before and after the treatment.
4, therapeutic effect: clinical 70 examples, cure 45 examples in the recent period, produce effects 10 examples, effective 6 examples, invalid 4 examples, total effective rate 93.8%.
Embodiment 5:
Model case: the field, the man, 40 years old, suffered from rheumatoid arthritis 3 years, take the made Chinese medicine oral liquid of embodiment of the invention l, every day early, middle and late respectively taking once, a dose is 20ml, 30 days is a course of treatment, cure two courses of treatment.
Embodiment 6:
Model case: together certain, the woman, 55 years old, suffered from rheumatoid arthritis 6 years, take the made Chinese medicine oral liquid of embodiment of the invention l, every day early, middle and late respectively taking once, a dose is 20ml, 30 days is a course of treatment, cure four courses of treatment.
Embodiment 7:
Model case: the hole, the man, 67 years old, suffered from rheumatoid arthritis 5 years, take the made Chinese medicine oral liquid of embodiment of the invention l, every day early, middle and late respectively taking once, a dose is 20ml, 30 days is a course of treatment, cure three courses of treatment.