CN105194227A - Traditional Chinese medicine pills for treating leucoderma and preparation method of traditional Chinese medicine pills - Google Patents

Traditional Chinese medicine pills for treating leucoderma and preparation method of traditional Chinese medicine pills Download PDF

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Publication number
CN105194227A
CN105194227A CN201510720091.0A CN201510720091A CN105194227A CN 105194227 A CN105194227 A CN 105194227A CN 201510720091 A CN201510720091 A CN 201510720091A CN 105194227 A CN105194227 A CN 105194227A
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chinese medicine
traditional chinese
radix
crude drug
preparation
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CN201510720091.0A
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吴小斌
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Abstract

The invention provides traditional Chinese medicine pills for treating leucoderma. The traditional Chinese medicine pills comprise raw materials as follows: Chinese yam, fructus lycii, astragalus membranaceus, prepared pinellia tuber, Indian bread, giant typhonium rhizomes, radix asparagi, cassia twigs, nutgrass galingale rhizomes, Chinese angelica, garter snakes, tangerine peel, radix aconiti lateralis preparata, little multibanded krait, starfish, ligia, tall gastrodia tuber, stir-fried date seeds, prepared rehmannia roots and liquorice. The invention further provides a preparation method of the traditional Chinese medicine pills. The method is simple, bitterness and part of harmful components are removed through pre-processing processes such as fumigation and the like, the stomach and blood vessels are not irritated, and adverse reactions caused by toxic components existing in traditional Chinese medicine raw materials after the pills are taken are avoided; natural traditional Chinese medicines are taken as raw materials, leucoderma is treated under comprehensive action of the medicines, no toxic or side effect is caused to human bodies, and the traditional Chinese medicine pills have efficacy of qi tonification, stagnation removal, wind dispelling, itching relief, activation of blood circulation and ecchymosis removal, take effect quickly, and have excellent treatment effect on leucoderma, and the treatment course is short.

Description

One treats leukodermic Chinese medicine pill and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines, relate to one and treat leukodermic Chinese medicine pill and preparation method thereof.
Background technology
Vitiligo is one of large pertinacious disease in the world dermopathic three, its Clinical symptoms main manifestations is that melanocyte reduces or depigmentation speckle appears in disappearance, form white macula for feature with the skin pigment depigmentation day after tomorrow, etiology and pathogenesis is more complicated, is the result of many factors comprehensive function.In recent years, most scholar thinks that vitiligo is a kind of autoimmune disease of polygenic inheritance, and humoral immunization and cellular immunization play an important role in vitiligo is formed to melanocytic destruction.
Because current leukodermic pathogenesis is still undistinct, so its treatment is still more difficult, be a difficult problem medically always.Chinese medicine is thought, leukodermic Etiological pathogenesis is stagnation of QI due to depression of the liver, deficiency of the liver and kindey, stagnation of QI-blood.Exopathogen is taken advantage of a weak point in opponent's defence and is attacked, and visitor enters flesh table, and meridians are obstructed, coagulation of QI-blood, and fur space between skin and muscles loses supports and the speckle that turns white, the how double congestion of course of disease elder.Lung governing qi, at body and skin, its Hua Mao, have Xuan Fawei gas, semen deposition is in physiological functions such as furs.Although the domestic and international medicine for therapy of vitiligo has a variety of at present, curative effect is all imprecise, take effect slow, the time is long, and have go back toxic side effect.
Summary of the invention
For the above-mentioned shortcoming existed in prior art, the invention provides one and treat leukodermic Chinese medicine pill, there is medication convenience, instant effect, short treating period, drug effect significantly, the advantage do not recur more, had no side effect;
Additionally provide the preparation method of above-mentioned Chinese medicine pill simultaneously.
Technical solution of the present invention is as follows:
One treats leukodermic Chinese medicine pill, comprises the crude drug of following weight portion: Flos Carthami 250-280, Rhizoma Chuanxiong 250-270, Radix Salviae Miltiorrhizae 250-270, Rhizoma Cyperi 250-270, Radix Angelicae Sinensis 250-270, Rhizoma Dioscoreae 250-280, Cortex Dictamni 250-280, Zaocys 255-265, HAICAN 120-130, Chinese forest frog 35-40, Radix Gentianae 255-265, SEMEN ASTRAGALI COMPLANATI 1000-1500, Fructus Tribuli 1000-1500, Fructus Psoraleae 255-265, Radix Astragali 250-270, Rhizoma Paridis 125-135, Radix Sophorae Flavescentis 255-265.
Preferably, the leukodermic Chinese medicine pill of above-mentioned treatment, comprises the crude drug of following weight portion:
Flos Carthami 260, Rhizoma Chuanxiong 260, Radix Salviae Miltiorrhizae 260, Rhizoma Cyperi 260, Radix Angelicae Sinensis 260, Rhizoma Dioscoreae 260, Cortex Dictamni 260, Zaocys 260, HAICAN 126, Chinese forest frog 38, Radix Gentianae 260, SEMEN ASTRAGALI COMPLANATI 1200, Fructus Tribuli 1200, Fructus Psoraleae 260, the Radix Astragali 260, Rhizoma Paridis 130, Radix Sophorae Flavescentis 130.
The present invention treats the preparation method of leukodermic Chinese medicine pill, and step is as follows:
1) take each crude drug by proportioning, fumigate 20-30min with the mixed solution of the white vinegar of mass ratio 2:3:1, Fructus Citri Limoniae juice and propolis respectively, then cross boiling water 3-5S, dry, for subsequent use;
2) Zaocys, HAICAN and Chinese forest frog are sprayed 95% alcohol dampening, Steam by water bath 2h, then dry pulverizing, cross 120 mesh sieves, then mix with remaining crude drug, micronizing, add lecithin, mix homogeneously, obtains medicated powder, for subsequent use;
3) to step 2) add the Mel of 1.0-1.2 times of quality in medicated powder, then add polyoxyethylene castor oil, refine as pill, leukodermic Chinese medicine pill must be treated.
Step 2) in, described accession capacity of Lecithin is the 0.2-0.5% of each crude drug gross mass.
In step 3), described polyoxyethylene castor oil addition is the 0.5-1% of each crude drug gross mass.
The heavy 6g of the every ball of the leukodermic Chinese medicine pill of described treatment.
Usage and dosage: 2 times on the one, sooner or later each 1 ball.
Beneficial effect of the present invention: with natural Chinese medicine for raw material, preparation method is simple, pretreatment is waited to remove pained and part harmful components by stifling, do not stimulate harmonization of the stomach blood vessel, alleviate Liver and kidney burden gastrointestinal tract generation pessimal stimulation increased the weight of because taking Chinese medicine, some untoward reaction that the toxic component simultaneously avoided because existing in raw material of Chinese medicine medicine causes after taking; The present invention utilizes the comprehensive function treatment vitiligo of each taste medicine, and to human non-toxic's side effect, have QI invigorating row stagnant, wind dispelling is antipruritic, the effect of speckle removing of invigorating blood circulation, instant effect, and treatment time is short, has excellent therapeutic effect to vitiligo.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated.
Embodiment 1
One treats leukodermic Chinese medicine pill, comprises the crude drug of following weight portion:
Flos Carthami 260, Rhizoma Chuanxiong 260, Radix Salviae Miltiorrhizae 260, Rhizoma Cyperi 260, Radix Angelicae Sinensis 260, Rhizoma Dioscoreae 260, Cortex Dictamni 260, Zaocys 260, HAICAN 126, Chinese forest frog 38, Radix Gentianae 260, SEMEN ASTRAGALI COMPLANATI 1200, Fructus Tribuli 1200, Fructus Psoraleae 260, the Radix Astragali 260, Rhizoma Paridis 130, Radix Sophorae Flavescentis 130.
Preparation method, step is as follows:
1) take each crude drug by proportioning, fumigate 20-30min with the mixed solution of the white vinegar of mass ratio 2:3:1, Fructus Citri Limoniae juice and propolis respectively, then cross boiling water 5S, dry, for subsequent use;
2) Zaocys, HAICAN and Chinese forest frog are sprayed 95% alcohol dampening, Steam by water bath 2h, then dry pulverizing, cross 120 mesh sieves, then mix with remaining crude drug, micronizing, add the lecithin of each crude drug gross mass 0.3%, mix homogeneously, obtains medicated powder, for subsequent use;
3) to step 2) add the Mel of 1.1 times of quality in medicated powder, then add the polyoxyethylene castor oil of each crude drug gross mass 0.8%, refine as pill, leukodermic Chinese medicine pill must be treated, the heavy 6g of every ball.
Embodiment 2
One treats leukodermic Chinese medicine pill, comprises the crude drug of following weight portion: Flos Carthami 250, Rhizoma Chuanxiong 250, Radix Salviae Miltiorrhizae 250, Rhizoma Cyperi 250, Radix Angelicae Sinensis 250, Rhizoma Dioscoreae 250, Cortex Dictamni 250, Zaocys 255, HAICAN 120, Chinese forest frog 35, Radix Gentianae 255, SEMEN ASTRAGALI COMPLANATI 1000, Fructus Tribuli 1000, Fructus Psoraleae 255, the Radix Astragali 250, Rhizoma Paridis 125, Radix Sophorae Flavescentis 255.
Preparation method, step is with embodiment 1.
Embodiment 3
One treats leukodermic Chinese medicine pill, comprises the crude drug of following weight portion: Flos Carthami 280, Rhizoma Chuanxiong 270, Radix Salviae Miltiorrhizae 270, Rhizoma Cyperi 270, Radix Angelicae Sinensis 270, Rhizoma Dioscoreae 280, Cortex Dictamni 280, Zaocys 265, HAICAN 130, Chinese forest frog 40, Radix Gentianae 265, SEMEN ASTRAGALI COMPLANATI 1500, Fructus Tribuli 1500, Fructus Psoraleae 265, the Radix Astragali 270, Rhizoma Paridis 135, Radix Sophorae Flavescentis 265.
Preparation method, step is with embodiment 1.
Clinical data
Test case standard: the patient meeting vitiligo clinical manifestation symptom.
Diagnostic criteria: according to tcm treatment according to syndrome differentiation principle, the strict standard diagnostics by this type of disease in the clinical drug demonstration plan for the treatment of vitiligo disease, according to the relevant Chinese medicine clinical research principle that Ministry of Public Health is developed and published, therapeutic effect is divided into recovery from illness, invalid and total effective rate judges.
The routine patient for the treatment of group 100,50 years old mean age, each patient takes embodiment of the present invention 1-3 Chinese medicine pill at random;
The routine patient of matched group 100, chooses the patient similar with its symptom according to treatment group patients with clinical manifestations symptom, and under identical treatment environment, the treatment vitiligo using pharmacy to sell has medicine;
To two groups of sufferer therapeutic effect, carry out clinical trail treatment, carry out record comparison to curative effect: medication one month, after three months, six months, two groups of patient outcomes are as shown in the table:
Above-mentioned data show, use the present invention to treat 100 routine patients of leukodermic Chinese medicine pill, and its curative effect comparatively uses the matched group patient of existing medicine at present good.
Choose model case to be below specifically described Chinese medicine pill of the present invention and effect.
Case 1:
Wang, man, 20 years old, white macula 2 × 1cm after bilateral ear, 5 years, took the embodiment of the present invention 1 Chinese medicine pill, 2 times on the one, sooner or later each 1 ball, and 65 days white maculas of taking medicine disappear, and follow up a case by regular visits to and have no recurrence after 1 year.
Case 2:
Korea Spro, man, 28 years old, right side Head And Face spread all over white macula, invalid through in many ways seeking medical advice, take the embodiment of the present invention 2 Chinese medicine pill, 2 times on the one, sooner or later each 1 ball, take this medicine after 4 months white macula substantially disappear, only lose right frontal eminence bean blotch and do not move back, follow up a case by regular visits to, within 4 years, do not recur increase.
Case 3:
Lee, female, 26 years old, patient's neck, face, shoulder, skin boundary knows the circular white macula distributing and differ in size, and develops gradually, within 2 years, seeks medical advice and has no effect, take the embodiment of the present invention 3 Chinese medicine pill, 2 times on the one, each 1 ball, takes medicine and fully recovers for 140 days, follow up a case by regular visits to and do not recur after 2 years sooner or later.

Claims (6)

1. treat a leukodermic Chinese medicine pill, it is characterized in that, comprise the crude drug of following weight portion: Flos Carthami 250-280, Rhizoma Chuanxiong 250-270, Radix Salviae Miltiorrhizae 250-270, Rhizoma Cyperi 250-270, Radix Angelicae Sinensis 250-270, Rhizoma Dioscoreae 250-280, Cortex Dictamni 250-280, Zaocys 255-265, HAICAN 120-130, Chinese forest frog 35-40, Radix Gentianae 255-265, SEMEN ASTRAGALI COMPLANATI 1000-1500, Fructus Tribuli 1000-1500, Fructus Psoraleae 255-265, Radix Astragali 250-270, Rhizoma Paridis 125-135, Radix Sophorae Flavescentis 255-265.
2. Chinese medicine pill according to claim 1, is characterized in that, comprises the crude drug of following weight portion:
Flos Carthami 260, Rhizoma Chuanxiong 260, Radix Salviae Miltiorrhizae 260, Rhizoma Cyperi 260, Radix Angelicae Sinensis 260, Rhizoma Dioscoreae 260, Cortex Dictamni 260, Zaocys 260, HAICAN 126, Chinese forest frog 38, Radix Gentianae 260, SEMEN ASTRAGALI COMPLANATI 1200, Fructus Tribuli 1200, Fructus Psoraleae 260, the Radix Astragali 260, Rhizoma Paridis 130, Radix Sophorae Flavescentis 130.
3. claim 1 or 2 treats a preparation method for leukodermic Chinese medicine pill, and it is characterized in that, step is as follows:
1) take each crude drug by proportioning, fumigate 20-30min with the mixed solution of the white vinegar of mass ratio 2:3:1, Fructus Citri Limoniae juice and propolis respectively, then cross boiling water 3-5S, dry, for subsequent use;
2) Zaocys, HAICAN and Chinese forest frog are sprayed 95% alcohol dampening, Steam by water bath 2h, then dry pulverizing, cross 120 mesh sieves, then mix with remaining crude drug, micronizing, add lecithin, mix homogeneously, obtains medicated powder, for subsequent use;
3) to step 2) add the Mel of 1.0-1.2 times of quality in medicated powder, then add polyoxyethylene castor oil, refine as pill, leukodermic Chinese medicine pill must be treated.
4. preparation method according to claim 3, is characterized in that: step 2) in, described accession capacity of Lecithin is the 0.2-0.5% of each crude drug gross mass.
5. preparation method according to claim 3, is characterized in that: in step 3), and described polyoxyethylene castor oil addition is the 0.5-1% of each crude drug gross mass.
6. preparation method according to claim 3, is characterized in that: the heavy 6g of the every ball of the leukodermic Chinese medicine pill of described treatment.
CN201510720091.0A 2015-10-30 2015-10-30 Traditional Chinese medicine pills for treating leucoderma and preparation method of traditional Chinese medicine pills Pending CN105194227A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105902722A (en) * 2016-05-05 2016-08-31 王保安 Traditional Chinese medicine composition for treating leucoderma and preparation method and application thereof
CN108783415A (en) * 2018-05-16 2018-11-13 林万君 Wood frog peptide zaocys dhumnade seabuckthorn fruit powder

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1368235A (en) * 2001-02-01 2002-09-11 杨孟君 Nano medicine for treating leukoderma and its preparing process
CN102362950A (en) * 2011-06-15 2012-02-29 王莲芬 Traditional Chinese medicine for treating leucoderma
CN104474195A (en) * 2014-12-24 2015-04-01 上海市徐汇区中心医院 Traditional Chinese medicine compound preparation for treating leucoderma and preparation method of traditional Chinese medicine compound preparation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1368235A (en) * 2001-02-01 2002-09-11 杨孟君 Nano medicine for treating leukoderma and its preparing process
CN102362950A (en) * 2011-06-15 2012-02-29 王莲芬 Traditional Chinese medicine for treating leucoderma
CN104474195A (en) * 2014-12-24 2015-04-01 上海市徐汇区中心医院 Traditional Chinese medicine compound preparation for treating leucoderma and preparation method of traditional Chinese medicine compound preparation

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105902722A (en) * 2016-05-05 2016-08-31 王保安 Traditional Chinese medicine composition for treating leucoderma and preparation method and application thereof
CN108783415A (en) * 2018-05-16 2018-11-13 林万君 Wood frog peptide zaocys dhumnade seabuckthorn fruit powder

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Application publication date: 20151230