CN102099029A - 治疗眼部病症的霉酚酸钠的pH值特定溶液 - Google Patents

治疗眼部病症的霉酚酸钠的pH值特定溶液 Download PDF

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Publication number
CN102099029A
CN102099029A CN2009801265755A CN200980126575A CN102099029A CN 102099029 A CN102099029 A CN 102099029A CN 2009801265755 A CN2009801265755 A CN 2009801265755A CN 200980126575 A CN200980126575 A CN 200980126575A CN 102099029 A CN102099029 A CN 102099029A
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China
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eye
nampa
solution
ocular
day
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CN2009801265755A
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English (en)
Chinese (zh)
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爱德华·庄
克莱夫·伯奇
李·米泽恩
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Aspreva International Ltd
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Aspreva International Ltd
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Publication of CN102099029A publication Critical patent/CN102099029A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN2009801265755A 2008-07-09 2009-07-09 治疗眼部病症的霉酚酸钠的pH值特定溶液 Pending CN102099029A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7941308P 2008-07-09 2008-07-09
US61/079,413 2008-07-09
PCT/IB2009/006683 WO2010004435A2 (en) 2008-07-09 2009-07-09 Formulations for treating eye disorders

Publications (1)

Publication Number Publication Date
CN102099029A true CN102099029A (zh) 2011-06-15

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ID=41505728

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801265755A Pending CN102099029A (zh) 2008-07-09 2009-07-09 治疗眼部病症的霉酚酸钠的pH值特定溶液

Country Status (6)

Country Link
US (1) US20100010082A1 (https=)
EP (1) EP2310008A4 (https=)
JP (1) JP2011527339A (https=)
CN (1) CN102099029A (https=)
CA (1) CA2729834A1 (https=)
WO (1) WO2010004435A2 (https=)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210196837A1 (en) * 2017-12-08 2021-07-01 The Johns Hopkins University Hypotonic hydrogel formulations for enhanced transport of active agents at mucosal surfaces
CN113473970A (zh) * 2018-12-27 2021-10-01 瑟菲斯眼科股份有限公司 用以治疗眼表疾病的眼科药物组合物和方法
CN113519461A (zh) * 2021-07-06 2021-10-22 江西中洪博元生物技术有限公司 伴刀豆球蛋白a诱导的小鼠干眼症模型的构建方法及应用
CN114028334A (zh) * 2021-12-10 2022-02-11 卓和药业集团股份有限公司 一种肺部给药的免疫抑制剂的制备方法
CN116133639A (zh) * 2019-12-20 2023-05-16 维奥梅治疗公司 用于治疗炎性疾病的制剂和方法

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CA2746527A1 (en) 2008-09-22 2010-03-25 Rxi Pharmaceuticals Corporation Rna interference in skin indications
US9745574B2 (en) 2009-02-04 2017-08-29 Rxi Pharmaceuticals Corporation RNA duplexes with single stranded phosphorothioate nucleotide regions for additional functionality
US20100331430A1 (en) * 2009-06-30 2010-12-30 Allergan, Inc. Pharmaceutical compositions containing propionic preservative components
CN106074591B (zh) 2010-03-24 2020-01-14 菲奥医药公司 眼部症候中的rna干扰
TWI544922B (zh) 2011-05-19 2016-08-11 愛爾康研究有限公司 高濃度歐羅派特錠（ｏｌｏｐａｔａｄｉｎｅ）眼用組成物
US8829053B2 (en) * 2011-12-07 2014-09-09 Rochal Industries Llp Biocidal compositions and methods of using the same
PL2968650T3 (pl) * 2013-03-14 2019-05-31 Panoptica Inc Preparaty do oczu do dostarczania leku do tylnego fragmentu oka
US11279934B2 (en) 2014-04-28 2022-03-22 Phio Pharmaceuticals Corp. Methods for treating cancer using nucleic acids targeting MDM2 or MYCN
WO2015168605A1 (en) 2014-05-01 2015-11-05 Rxi Pharmaceuticals Corporation Methods for treatment of disorders in the front of the eye utilizing nucleic acid molecules
KR20170043655A (ko) * 2014-09-09 2017-04-21 아르투로 솔리스 헤레라 멜라닌 및 멜라닌 유사체, 전구체, 및 유도체로 안과 질병, 질환, 및 증상의 치료 및 예방을 위한 방법
US9789080B2 (en) * 2015-09-04 2017-10-17 Insite Vision Incorporated Ophthalmic formulations of mycophenolic acid
WO2019060696A1 (en) * 2017-09-25 2019-03-28 Surface Pharmaceuticals, Inc. OPTHALMIC PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF OCULAR SURFACE DISEASE
US20230158045A1 (en) * 2017-09-25 2023-05-25 Surface Ophthalmics, Inc. Pharmaceutical compositions of mycophenolic acid and/or betamethasone for the treatment of ocular disorders
US12310981B2 (en) 2021-05-10 2025-05-27 Surface Ophthalmics, Inc. Use of chondroitin sulfate for relieving ocular pain
US12440510B2 (en) 2021-05-10 2025-10-14 Surface Ophthalmics, Inc. Use of chondroitin sulfate for relieving ocular pain

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US3880995A (en) * 1973-05-14 1975-04-29 Lilly Co Eli Treatment of arthritis with mycophenolic acid and derivatives
US4686234A (en) * 1985-11-27 1987-08-11 Syntex (U.S.A) Inc. Mycophenolic acid derivatives in the treatment of inflammatory diseases, in particular rheumatoid arthritis
US4753935A (en) * 1987-01-30 1988-06-28 Syntex (U.S.A.) Inc. Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions
KR920003601B1 (ko) * 1987-09-03 1992-05-04 유니버시티 어브 죠지아 리서취 화운데이션 인코포레이티드 점안 싸이클로스포린(cyclosporin)의 조성물
US5283257A (en) * 1992-07-10 1994-02-01 The Board Of Trustees Of The Leland Stanford Junior University Method of treating hyperproliferative vascular disease
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CZ301771B6 (cs) * 1993-10-01 2010-06-16 Syntex (U.S.A.) Llc. Farmaceutický prostredek ve forme suchého granulátu obsahující mofetil mykofenolát nebo kyselinu mykofenolovou a zpusob jeho prípravy
JPH0930966A (ja) * 1995-07-24 1997-02-04 Gakuzo Tamura 眼科用新規製剤
ID18663A (id) * 1996-04-12 1998-04-30 Novartis Ag Komposisi farmasi berlapis enterik
US6670398B2 (en) * 1997-05-14 2003-12-30 Atherogenics, Inc. Compounds and methods for treating transplant rejection
US6239113B1 (en) * 1999-03-31 2001-05-29 Insite Vision, Incorporated Topical treatment or prevention of ocular infections
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US6482799B1 (en) * 1999-05-25 2002-11-19 The Regents Of The University Of California Self-preserving multipurpose ophthalmic solutions incorporating a polypeptide antimicrobial
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US8372814B2 (en) * 2004-06-07 2013-02-12 Ista Pharmaceuticals, Inc. Ophthalmic formulations and uses thereof
US20060069150A1 (en) * 2004-07-20 2006-03-30 Sandor Molnar Processes for preparation of crystalline mycophenolate sodium

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210196837A1 (en) * 2017-12-08 2021-07-01 The Johns Hopkins University Hypotonic hydrogel formulations for enhanced transport of active agents at mucosal surfaces
CN113473970A (zh) * 2018-12-27 2021-10-01 瑟菲斯眼科股份有限公司 用以治疗眼表疾病的眼科药物组合物和方法
CN116133639A (zh) * 2019-12-20 2023-05-16 维奥梅治疗公司 用于治疗炎性疾病的制剂和方法
CN113519461A (zh) * 2021-07-06 2021-10-22 江西中洪博元生物技术有限公司 伴刀豆球蛋白a诱导的小鼠干眼症模型的构建方法及应用
CN114028334A (zh) * 2021-12-10 2022-02-11 卓和药业集团股份有限公司 一种肺部给药的免疫抑制剂的制备方法
CN114028334B (zh) * 2021-12-10 2023-08-29 卓和药业集团股份有限公司 一种肺部给药的免疫抑制剂的制备方法

Also Published As

Publication number Publication date
US20100010082A1 (en) 2010-01-14
WO2010004435A3 (en) 2010-06-24
EP2310008A4 (en) 2014-03-05
CA2729834A1 (en) 2010-01-14
JP2011527339A (ja) 2011-10-27
WO2010004435A2 (en) 2010-01-14
EP2310008A2 (en) 2011-04-20
WO2010004435A9 (en) 2010-08-26

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Application publication date: 20110615