CN102083852A - 环孢菌素类似物及其在治疗hcv感染中的应用 - Google Patents

环孢菌素类似物及其在治疗hcv感染中的应用 Download PDF

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Publication number
CN102083852A
CN102083852A CN2009801261909A CN200980126190A CN102083852A CN 102083852 A CN102083852 A CN 102083852A CN 2009801261909 A CN2009801261909 A CN 2009801261909A CN 200980126190 A CN200980126190 A CN 200980126190A CN 102083852 A CN102083852 A CN 102083852A
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group
alkyl
amino
randomly
cyclosporin
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Chinese (zh)
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李科强
艾哈迈德·玛麦
迈克尔·罗伯特·佩尔
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Scynexis Inc
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Scynexis Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN2009801261909A 2008-06-06 2009-06-05 环孢菌素类似物及其在治疗hcv感染中的应用 Pending CN102083852A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5964908P 2008-06-06 2008-06-06
US61/059,649 2008-06-06
PCT/US2009/003411 WO2010002428A2 (en) 2008-06-06 2009-06-05 Novel macrocyclic peptides

Publications (1)

Publication Number Publication Date
CN102083852A true CN102083852A (zh) 2011-06-01

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801261909A Pending CN102083852A (zh) 2008-06-06 2009-06-05 环孢菌素类似物及其在治疗hcv感染中的应用

Country Status (6)

Country Link
US (1) US9090671B2 (enExample)
EP (1) EP2280989B1 (enExample)
JP (1) JP5820722B2 (enExample)
CN (1) CN102083852A (enExample)
CA (1) CA2724523A1 (enExample)
WO (1) WO2010002428A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109485771A (zh) * 2018-10-30 2019-03-19 焦作中维特品药业股份有限公司 一种交联聚维酮的制备方法
CN114230498A (zh) * 2021-12-30 2022-03-25 湖北华世通生物医药科技有限公司 β-(二甲氨基)乙基对甲苯磺酸巯酯盐酸盐的制备方法

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JP5322647B2 (ja) * 2005-09-30 2013-10-23 スシネキス インク ウイルス感染の治療及び予防のためのシクロスポリンａのアリールアルキル及びヘテロアリールアルキル誘導体
US8188052B2 (en) 2006-05-19 2012-05-29 Scynexis, Inc. Method for the treatment and prevention of ocular disorders
KR101089112B1 (ko) * 2006-06-02 2011-12-06 피씨 제스띠옹 에스.아.에스. 활성 전자 관리
US20090306033A1 (en) * 2008-06-06 2009-12-10 Keqiang Li Novel cyclic peptides
CA2724523A1 (en) 2008-06-06 2010-01-07 Scynexis, Inc. Novel macrocyclic peptides
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US20140050728A1 (en) 2011-01-28 2014-02-20 Board Of Regents Of The University Of Nebraska Methods and compositions for inhibiting cyclophilin d for the treatment and prevention of obesity and kidney indications
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JP7277222B2 (ja) 2019-03-29 2023-05-18 出光興産株式会社 潤滑油組成物
JP2022551161A (ja) * 2019-10-12 2022-12-07 ファーサイト メディカル テクノロジー （シャンハイ） カンパニー リミテッド ネフロトキシン誘発性腎障害の処置及び予防

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109485771A (zh) * 2018-10-30 2019-03-19 焦作中维特品药业股份有限公司 一种交联聚维酮的制备方法
CN114230498A (zh) * 2021-12-30 2022-03-25 湖北华世通生物医药科技有限公司 β-(二甲氨基)乙基对甲苯磺酸巯酯盐酸盐的制备方法
CN114230498B (zh) * 2021-12-30 2023-11-17 湖北华世通生物医药科技有限公司 β-(二甲氨基)乙基对甲苯磺酸巯酯盐酸盐的制备方法

Also Published As

Publication number Publication date
WO2010002428A2 (en) 2010-01-07
EP2280989B1 (en) 2016-02-10
CA2724523A1 (en) 2010-01-07
EP2280989A2 (en) 2011-02-09
JP2011523952A (ja) 2011-08-25
JP5820722B2 (ja) 2015-11-24
US9090671B2 (en) 2015-07-28
US20090312300A1 (en) 2009-12-17
WO2010002428A3 (en) 2010-03-11

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