CN102057935A - Bactericidal composition containing imidazole - Google Patents
Bactericidal composition containing imidazole Download PDFInfo
- Publication number
- CN102057935A CN102057935A CN2011100031557A CN201110003155A CN102057935A CN 102057935 A CN102057935 A CN 102057935A CN 2011100031557 A CN2011100031557 A CN 2011100031557A CN 201110003155 A CN201110003155 A CN 201110003155A CN 102057935 A CN102057935 A CN 102057935A
- Authority
- CN
- China
- Prior art keywords
- glyoxalin
- bactericidal composition
- prochloraz
- probenazole
- percentage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000005820 Prochloraz Substances 0.000 claims abstract description 46
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- TVLSRXXIMLFWEO-UHFFFAOYSA-N prochloraz Chemical compound C1=CN=CN1C(=O)N(CCC)CCOC1=C(Cl)C=C(Cl)C=C1Cl TVLSRXXIMLFWEO-UHFFFAOYSA-N 0.000 claims abstract description 46
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Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to a bactericidal composition containing imidazole, which comprises an active component A and an active component B, wherein the active component A is imidazole, the active component B is selected from one of the following bactericides: carbendazim, thiophanate methyl, probenazole, prochloraz, imazalil and triflumizole, and the weight percentage of the active component A to the active component B is (1-40%): (1-80%). Adjuvant and excipient are added to the active components to prepare wettable powder, water dispersible granules, suspending agents or suspending emulsion. The bactericidal composition can be used for preventing and treating scab, ring spot, alternaria leaf spot, anthracnose, spot anthracnose, shot hole and powdery mildew. The bactericidal composition can resist rain wash, and has obvious synergistic effect.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of bactericidal composition on crop pest that contains glyoxalin.
Technical background
Glyoxalin, English name: imibenconazole, molecular formula: C
17H
13C
L3N
4S, chemical name: 4-benzyl chloride base N-(2,4 dichloro benzene base)-2 (1H-1,2,4-triazol-1-yl) thioacetamide ester, structural formula:
Glyoxalin is the broad spectrum activity triazole bactericidal agent.The main mechanism of action is to destroy and stop the biosynthesis of the after birth important composition composition ergosterol of threading of germ, thereby destroys the formation of cell membrane, causes germ death.Glyoxalin has protection and therapeutic action, can rapid osmotic after being sprayed onto on the crop in plant corpus, resistance of rainwater washing against.
The agent of glyoxalin list is used for a long time, and disease is developed immunity to drugs, and causes the problem that dosage strengthens, preventive effect reduces, the lasting period shortens, and is unfavorable for environment sustainable development.And that the active ingredient of the different mechanisms of action is carried out is composite, is to delay the disease method commonly used that develops immunity to drugs, and according to the effect in the production application, judge this composite be synergistic effect or antagonism.Complex role is more significantly filled a prescription, and can obviously improve preventive effect, reduces the dosage of agricultural chemicals greatly, also can enlarge fungicidal spectrum, improves germicidal efficiency.Glyoxalin is different with the effective active composition B mechanism of action, mutually composite have good synergistic effect within the specific limits, and about glyoxalin and carbendazim, thiophanate-methyl, probenazole, Prochloraz, press down the relevant composite of mould azoles, fluorine bacterium azoles, do not see relevant report at present at home and abroad as yet.
Summary of the invention
The objective of the invention is to propose a kind of have synergistic function, use cost is low, preventive effect the is good bactericidal composition that contains glyoxalin and effective active composition B.
The present invention is achieved through the following technical solutions:
A kind of bactericidal composition that contains glyoxalin, it is characterized in that: the percentage by weight of A, two kinds of active components of B is 1～40%: 1～80%, described A component is a glyoxalin, and the B component is selected from carbendazim, thiophanate-methyl, probenazole, Prochloraz, presses down a kind of of mould azoles, fluorine bacterium azoles.
The described glyoxalin bactericidal composition that contains is characterized in that: wherein the percentage by weight of glyoxalin and effective active composition B is 1～35%: 5～70%.
The described bactericidal composition that contains glyoxalin and carbendazim is characterized in that: wherein the percentage by weight of glyoxalin and carbendazim is 5～30%: 10～60%.
The described bactericidal composition that contains glyoxalin and thiophanate-methyl is characterized in that: wherein the percentage by weight of glyoxalin and thiophanate-methyl is 5～30%: 10～60%.
The described bactericidal composition that contains glyoxalin and probenazole is characterized in that: wherein the percentage by weight of glyoxalin and probenazole is 5～30%: 10～50%.
The described bactericidal composition that contains glyoxalin and Prochloraz is characterized in that: wherein the percentage by weight of glyoxalin and Prochloraz is 5～30%: 10～50%.
Described glyoxalin and the bactericidal composition that presses down mould azoles of containing, it is characterized in that: wherein glyoxalin is 5～30%: 10～50% with the percentage by weight that presses down mould azoles.
The described bactericidal composition that contains glyoxalin and fluorine bacterium azoles is characterized in that: wherein the percentage by weight of glyoxalin and fluorine bacterium azoles is 5～30%: 5～40%.
The described bactericidal composition that contains glyoxalin, wherein the effective active component content accounts for 1～95% of gross weight, is preferably 20～80%.
The described bactericidal composition that contains glyoxalin is made wetting powder, water dispersible granules, suspending agent or suspension emulsion.
When making wetting powder, composition comprises following constituent content: glyoxalin 1～40%, effective active composition B 1～80%, dispersant 3～10%, wetting agent 2～10%, filler 8～93%.
Glyoxalin, effective active composition B, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, promptly can be made into the wetting powder product of the present composition.
When making water dispersible granules, composition comprises following constituent content: glyoxalin 1～40%, effective active composition B1～80%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, filler 8～93%.
Glyoxalin, effective active composition B, dispersant, wetting agent, disintegrant, filler etc. are obtained the particle diameter that needs through comminution by gas stream together, obtain the materials of granulating.It is interior through after granulation and the drying to expect that product are quantitatively sent the fluidized bed granulation dryer to, makes present composition water dispersible granules product.
Comprise following constituent content when composition is made suspending agent: glyoxalin 1～20%, active ingredient B 1～40%, dispersant 2～10%, wetting agent 2～10%, defoamer 0.1～1%, thickener 0.1～2%, antifreeze 0～8%, stabilizing agent 0%～3%, deionized water add to 100%.
Dispersant, wetting agent, defoamer, thickener, antifreeze in the above-mentioned formulation material are mixed through high speed shear, glyoxalin, adding active ingredient B, ball milling is 2～3 hours in ball mill, makes diameter of particle all below 5 μ m, makes present composition suspending agent product.
Comprise following constituent content when composition is made suspension emulsion: glyoxalin 1～20%, effective active composition B 1～40%, emulsifier 2～12%, dispersant 2～10%, defoamer 0.1～2%, thickener 0.1～2%, antifreeze 0.1～8%, stabilizing agent 0.05～3%, water add to 100%.
Dispersant, defoamer, thickener, antifreeze, stabilizing agent in the above-mentioned formulation material are mixed through high speed shear, add the former medicine of glyoxalin, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make the glyoxalin suspending agent, then with the former medicine of effective active composition B, emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, make present composition suspension emulsion product.
Described dispersant is selected from alkylnaphthalene sulfonate, two (alkyl) naphthalenesulfonate formaldehyde condensation compound, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, the naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy is phonetic, aliphatic amine polyoxyethylene is phonetic, polyoxyethylene carboxylate, during the ester polyoxyethylene is phonetic one or more.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, silkworm excrement, the soapberry powder.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, the aluminium chloride.
Described binding agent is selected from: one or more in gum Arabic, xanthans, sodium phosphate trimer, phenolic resins, sodium alginate, white dextrin, methylcellulose, PAA, polyvinylpyrrolidone, crospolyvinylpyrrolidone, polyethylene glycol, the polyvinyl alcohol.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, the polyethylene glycol.
Described defoamer is selected from: silicone, C
8～10Aliphatic alcohols, C
10～20In saturated fat acids (as capric acid) and acid amides, silicone oil, the silicone compound one or more.
Described emulsifier is selected from: agricultural newborn 500# (alkyl benzene calcium sulfonate), OP series phosphate (polyoxyethylene nonylphenol ether phosphate), 600# phosphate (phenyl phenol polyoxy ethyl ether phosphate), styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, farming newborn 400# (benzyl dimethyl phenol polyoxy ethyl ether), farming newborn 600# (phenyl phenol polyoxy ethyl ether), Nongru-700 # (alkylphenol-formaldehyde resin polyoxy ethyl ether), farming newborn 36# (phenethyl fluosite polyoxy ethyl ether), farming newborn 1600# (phenethyl phenol polyoxy ethyl polypropylene-base ether), ethylene oxide-propylene oxide block copolymer, OP series (polyoxyethylene nonylphenol ether), By series (castor oil polyoxyethylene ether), farming newborn 33# (alkylaryl polyoxyethylene polyoxypropylene ether), farming newborn 34# (alkylaryl polyoxyethylene poly-oxygen propylene aether), sapn series (sorbitan monostearate), tween series (sorbitan fatty acid ester APEO), in the AEO series (the pure APEO of fat) one or more.
Described stabilizing agent is selected from: one or more in BHT, triphenyl phosphite, epoxychloropropane, tributyl phosphate, triethanolamine, diethanol amine, the monoethanolamine.
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate.
Beneficial effect of the present invention: (1) present composition effective active composition glyoxalin and effective active composition B belong to the bactericide of two kinds of different mechanisms of action, and both are mixed mutually and can produce conflict; (2) present composition has good synergistic effect within the specific limits, and preventive effect is higher than single agent, and dosage is little; (3) the present invention not with an organic solvent is not difficult for producing poisoning, is convenient to transportation and storage; (4) present composition has enlarged fungicidal spectrum, and diseases such as crop scab, ring spot, spot defoliation, anthracnose, anthrachose of grape, shot hole, powdery mildew are all had special efficacy.
Embodiment
To further instruction of the present invention, the percentage among the embodiment all is weight percentage below in conjunction with embodiment, but the present invention is not limited thereto.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.
Application Example one
Example 1 66% glyoxalin carbendazol wettable powder
Glyoxalin 6%, carbendazim 60%, the phonetic formaldehyde condensation products sulphate 8% of alkylphenol-polyethenoxy, silkworm excrement 7%, bentonite add to 100%, and mixture carries out comminution by gas stream, makes 66% glyoxalin carbendazol wettable powder.
Example 2 80% glyoxalin carbendazol wettable powders
Glyoxalin 10%, carbendazim 70%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 7%, Nekal BX 5%, white carbon add to 100%, and mixture carries out comminution by gas stream, make 80% glyoxalin carbendazol wettable powder.
Example 3 50% glyoxalin carbendazim water dispersing granules
Glyoxalin 5%, carbendazim 45%, soapberry powder 4%, alkylphenol-polyethenoxy are phonetic 6%, urea 1.3%, diatomite add to 100%, mixed 50% glyoxalin carbendazim water dispersing granule.
Example 4 60% glyoxalin carbendazim water dispersing granules
Glyoxalin 5%, carbendazim 55%, neopelex 6%, polycarboxylate 8%, bentonite add to 100%, the mixed 60% glyoxalin carbendazim water dispersing granule that gets.
Example 5 12% glyoxalin carbendazim suspending agents
Glyoxalin 2%, carbendazim 10%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 7%, spaonin powder 6%, C
8～10Aliphatic alcohols 0.5%, polyvinylpyrrolidone 1.6%, propane diols 1.4%, deionized water add to 100%, the mixed 12% glyoxalin carbendazim suspending agent that gets.
Example 6 48% glyoxalin carbendazim suspending agents
Glyoxalin 3%, carbendazim 45%, aliphatic amine polyoxyethylene are phonetic 6%, wetting and penetrating agent F5%, silicone oil 0.4%, gum Arabic 1.5%, ethylene glycol 1.7%, deionized water add to 100%, mixed 48% glyoxalin carbendazim suspending agent.
Example 7 55% glyoxalin thiophanate-methyl wetting powders
Glyoxalin 5%, thiophanate-methyl 50%, naphthalene sulfonic acid-formaldehyde condensation product 6%, soapberry powder 5%, kaolin add to 100%, and mixture carries out comminution by gas stream, make 55% glyoxalin thiophanate-methyl wetting powder.
Example 8 81% glyoxalin thiophanate-methyl wetting powders
Glyoxalin 1%, thiophanate-methyl 80%, polyoxyethylene carboxylate 6%, Nekal BX 5%, white carbon add to 100%, and mixture carries out comminution by gas stream, make 81% glyoxalin thiophanate-methyl wetting powder.
Example 9 32% glyoxalin thiophanate-methyl water dispersible granules
Glyoxalin 2%, thiophanate-methyl 30%, octylphenol polyethylene oxyethylene group ether sulfate 7%, spaonin powder 5%, ammonium sulfate 1.2%, diatomite add to 100%, the mixed 32% glyoxalin thiophanate-methyl water dispersible granules that gets.
Example 10 63% glyoxalin thiophanate-methyl water dispersible granules
Glyoxalin 3%, thiophanate-methyl 60%, lignosulfonates 8%, wetting and penetrating agent F6%, bentonite add to 100%, the mixed 63% glyoxalin thiophanate-methyl water dispersible granules that gets.
Example 11 10% glyoxalin thiophanate-methyl suspending agents
Glyoxalin 5%, thiophanate-methyl 5%, polyoxyethylene carboxylate 7%, neopelex 5%, C
10～20Saturated fat acids 0.2%, polyvinylpyrrolidone 1.4%, polyethylene glycol 1.8%, deionized water add to 100%, the mixed 10% glyoxalin thiophanate-methyl suspending agent that gets.
Example 12 42% glyoxalin thiophanate-methyl suspending agents
Glyoxalin 7%, thiophanate-methyl 35%, aryl phenol polyoxyethylene succinate sulfonate 5%, Nekal BX 5%, silicone compound 0.5%, methylcellulose 1.2%, glycerine 1.4%, deionized water add to 100%, the mixed 42% glyoxalin thiophanate-methyl suspending agent that gets.
Example 13 50% glyoxalin probenazole wetting powders
Glyoxalin 10%, probenazole 40%, alkyl benzene sulfonate calcium salt 7%, wetting and penetrating agent F 5%, kaolin add to 100%, and mixture carries out comminution by gas stream, make 50% glyoxalin probenazole wetting powder.
Example 14 75% glyoxalin probenazole wetting powders
Glyoxalin 15%, probenazole 60%, lignosulfonates 7%, soapberry powder 5%, attapulgite add to 100%, and mixture carries out comminution by gas stream, make 75% glyoxalin probenazole wetting powder.
Example 15 56% glyoxalin probenazole water dispersible granules
Glyoxalin 6%, probenazole 50%, the phonetic formaldehyde condensation products sulphate 8% of alkylphenol-polyethenoxy, silkworm excrement 6%, bentonite add to 100%, the mixed 56% glyoxalin probenazole water dispersible granules that gets.
Example 16 72% glyoxalin probenazole water dispersible granules
Glyoxalin 8%, probenazole 64%, polycarboxylate 6%, neopelex 5%, aluminium chloride 1.1%, kaolin add to 100%, the mixed 72% glyoxalin probenazole water dispersible granules that gets.
Example 17 25% glyoxalin probenazole suspending agents
Glyoxalin 5%, probenazole 20%, alkyl benzene sulfonate calcium salt 7%, lauryl sodium sulfate 6%, C
10～20Saturated fat acids 0.2%, xanthans 1.8%, ethylene glycol 1.7%, deionized water add to 100%, the mixed 25% glyoxalin probenazole suspending agent that gets.
Example 18 36% glyoxalin probenazole suspending agents
Glyoxalin 4%, probenazole 32%, lignosulfonates 6%, wetting and penetrating agent F 5%, silicone oil 0.4%, sodium phosphate trimer 1.5%, glycerine 1.7%, deionized water add to 100%, the mixed 36% glyoxalin probenazole suspending agent that gets.
Example 19 10% glyoxalin probenazole suspension emulsions
Glyoxalin 5%, probenazole 5%, polyoxyethylene carboxylate 7%, soapberry powder 5%, polyvinylpyrrolidone 1.5%, agricultural newborn 400#7%, ethylene glycol 1.6%, silicone compound 0.3%, water add to 100%, through the mixed 10% glyoxalin probenazole suspension emulsion that gets.
Example 20 36% glyoxalin probenazole suspension emulsions
Glyoxalin 12%, probenazole 24%, lignosulfonates 7%, Nekal BX 4%, xanthans 1.4%, agricultural newborn 500#7%, polyethylene glycol 1.5%, C
8～10Aliphatic alcohols 0.5%, water add to 100%, through the mixed 36% glyoxalin probenazole suspension emulsion that gets.
Example 21 45% glyoxalin Prochloraz wetting powders
Glyoxalin 5%, Prochloraz 40%, aliphatic amine polyoxyethylene are phonetic 6%, wetting and penetrating agent F4%, kaolin add to 100%, and mixture carries out comminution by gas stream, makes 45% glyoxalin Prochloraz wetting powder.
Example 22 76% glyoxalin Prochloraz wetting powders
Glyoxalin 6%, Prochloraz 70%, two (alkyl) naphthalenesulfonate formaldehyde condensation compound 7%, silkworm excrement 6%, white carbon add to 100%, and mixture carries out comminution by gas stream, make 76% glyoxalin Prochloraz wetting powder.
Example 23 50% glyoxalin Prochloraz water dispersible granules
Glyoxalin 10%, Prochloraz 40%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 7%, lauryl sodium sulfate 6%, bentonite add to 100%, the mixed 50% glyoxalin Prochloraz water dispersible granules that gets.
Example 24 75% glyoxalin Prochloraz water dispersible granules
Glyoxalin 15%, Prochloraz 60%, polyoxyethylene carboxylate 6%, Nekal BX F4%, urea 1.5%, diatomite add to 100%, the mixed 75% glyoxalin Prochloraz water dispersible granules that gets.
Example 25 30% glyoxalin Prochloraz suspending agents
Glyoxalin 10%, Prochloraz 20%, alkyl benzene sulfonate calcium salt 8%, wetting and penetrating agent F 6%, C
8～10Aliphatic alcohols 0.5%, xanthans 1.7%, ethylene glycol 1.5%, deionized water add to 100%, the mixed 30% glyoxalin Prochloraz suspending agent that gets.
Example 26 35% glyoxalin Prochloraz suspending agents
Glyoxalin 7%, Prochloraz 28%, polyoxyethylene carboxylate 6%, spaonin powder 5%, silicone oil 0.4%, sodium phosphate trimer 1.2%, propane diols 1.6%, deionized water add to 100%, the mixed 35% glyoxalin Prochloraz suspending agent that gets.
Example 27 12% glyoxalin Prochloraz suspension emulsions
Glyoxalin 6%, Prochloraz 6%, lignosulfonates 5%, soapberry powder 4%, C
10～20Saturated fat acids 0.5%, methylcellulose 1.6%, agricultural newborn 600#6%, ethylene glycol 1.8%, water add to 100%, and the aforementioned formula material is mixed, and promptly make 12% glyoxalin Prochloraz suspension emulsion.
Example 28 36% glyoxalin Prochloraz suspension emulsions
Glyoxalin 4%, Prochloraz 32%, octylphenol polyethylene oxyethylene group ether sulfate 8%, lauryl sodium sulfate 6%, C
8～10Aliphatic alcohols 0.7%, xanthans 1.4%, agricultural newborn 34#7%, glycerine 1.7%, water add to 100%, and the aforementioned formula material is mixed, and promptly make 36% glyoxalin Prochloraz suspension emulsion.
Example 29 60% glyoxalins press down mould azoles wetting powder
Glyoxalin 12%, press down mould azoles 48%, naphthalene sulfonic acid-formaldehyde condensation product 5%, spaonin powder 4%, kaolin and add to 100%, mixture carries out comminution by gas stream, makes 60% glyoxalin and presses down mould azoles wetting powder.
Example 30 70% glyoxalins press down mould azoles wetting powder
Glyoxalin 20%, press down that mould azoles 50%, ester polyoxyethylene are phonetic 7%, soapberry powder 6%, attapulgite add to 100%, mixture carries out comminution by gas stream, makes 70% glyoxalin and presses down mould azoles wetting powder.
Example 31 50% glyoxalins press down mould azoles water dispersible granules
Glyoxalin 10%, press down mould azoles 40%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 8%, wetting and penetrating agent F 7%, bentonite and add to 100%, mixed that 50% glyoxalin press down mould azoles water dispersible granules.
Example 32 75% glyoxalins press down mould azoles water dispersible granules
Glyoxalin 5%, press down mould azoles 70%, alkyl benzene sulfonate calcium salt 6%, neopelex 4%, aluminium chloride 1.2%, kaolin and add to 100%, mixed that 75% glyoxalin press down mould azoles water dispersible granules.
Example 33 16% glyoxalins press down mould azole suspending agent
Glyoxalin 8%, press down mould azoles 8%, alkyl benzene sulfonate calcium salt 7%, spaonin powder 5%, C
10～20Saturated fat acids 0.6%, gum Arabic 1.2%, ethylene glycol 1.6%, deionized water add to 100%, and be mixed that 16% glyoxalin presses down mould azole suspending agent.
Example 34 35% glyoxalins press down mould azole suspending agent
Glyoxalin 10%, press down mould azoles 25%, octylphenol polyethylene oxyethylene group ether sulfate 8%, wetting and penetrating agent F 6%, silicone oil 0.4%, polyvinyl alcohol 1.5%, glycerine 1.4%, deionized water and add to 100%, mixed that 35% glyoxalin press down mould azole suspending agent.
Example 35 15% glyoxalins press down mould azoles suspension emulsion
Glyoxalin 5%, press down that mould azoles 10%, aliphatic amine polyoxyethylene are phonetic 6%, Nekal BX 5%, silicone compound 0.2%, sodium phosphate trimer 1.6%, tween series 5%, propane diols 1.7%, water add to 100%, the aforementioned formula material is mixed, promptly make 15% glyoxalin and press down mould azoles suspension emulsion.
Example 36 45% glyoxalins press down mould azoles suspension emulsion
Glyoxalin 5%, press down mould azoles 40%, lignosulfonates 5%, spaonin powder 4%, C
10～20Saturated fat acids 0.3%, polyvinylpyrrolidone 1.3%, OP series phosphate 6%, polyethylene glycol 1.6%, water add to 100%, and the aforementioned formula material is mixed, and promptly make 45% glyoxalin and press down mould azoles suspension emulsion.
Example 37 42% glyoxalin triflumizole wettable powders
Glyoxalin 20%, fluorine bacterium azoles 22%, the phonetic formaldehyde condensation products sulphate 8% of alkylphenol-polyethenoxy, silkworm excrement 6%, attapulgite add to 100%, and mixture carries out comminution by gas stream, makes 42% glyoxalin triflumizole wettable powder.
Example 38 45% glyoxalin triflumizole wettable powders
Glyoxalin 15%, fluorine bacterium azoles 30%, naphthalene sulfonic acid-formaldehyde condensation product 7%, wetting and penetrating agent F 5%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 45% glyoxalin triflumizole wettable powder.
Example 39 36% glyoxalin triflumizole water dispersants
Glyoxalin 16%, fluorine bacterium azoles 20%, polyoxyethylene carboxylate 8%, neopelex 7%, bentonite add to 100%, the mixed 36% glyoxalin triflumizole water dispersant that gets.
Example 40 40% glyoxalin triflumizole water dispersants
Glyoxalin 5%, fluorine bacterium azoles 35%, octylphenol polyethylene oxyethylene group ether sulfate 6%, soapberry powder 5%, bentonite add to 100%, the mixed 40% glyoxalin triflumizole water dispersant that gets.
Example 41 20% glyoxalin fluorine bacterium azole suspending agents
Glyoxalin 10%, fluorine bacterium azoles 10%, alkyl benzene sulfonate calcium salt 7%, lauryl sodium sulfate 5%, silicone compound 0.3%, gum Arabic 1.5%, glycerine 1.2%, deionized water adds to 100%, the mixed 20% glyoxalin fluorine bacterium azole suspending agent that gets.
Example 42 30% glyoxalin fluorine bacterium azole suspending agents
Glyoxalin 20%, fluorine bacterium azoles 10%, polycarboxylate 8%, wetting and penetrating agent F 6%, C
10～20Saturated fat acids 0.4%, polyethylene glycol 1.5%, deionized water adds to 100%, the mixed 30% glyoxalin fluorine bacterium azole suspending agent that gets.
Example 43 15% glyoxalin fluorine bacterium azoles suspension emulsions
Glyoxalin 10%, fluorine bacterium azoles 5%, two (alkyl) naphthalenesulfonate formaldehyde condensation compound 5%, silkworm excrement 4%, xanthans 1.5%, propane diols 1.4%, silicone oil 0.6%, agricultural newborn 1600#5%, water add to 100%, the mixed 15% glyoxalin fluorine bacterium azoles suspension emulsion that gets.
Example 44 40% glyoxalin fluorine bacterium azoles suspension emulsions
Glyoxalin 10%, fluorine bacterium azoles 30%, lignosulfonates 6%, Nekal BX 5%, PAA 1.2%, ethylene glycol 1.7%, C
8～10Aliphatic alcohols 0.5%, Nongru-700 #7%, water add to 100%, the mixed 40% glyoxalin fluorine bacterium azoles suspension emulsion that gets.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.Pass through Toxicity Determination earlier, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect, on this basis, carry out field trial again.
Glyoxalin and active component B (B is selected from carbendazim, thiophanate-methyl, probenazole, Prochloraz, presses down a kind of of mould azoles, fluorine bacterium azoles) are composite to the crop pest Toxicity Determination.
After the effective inhibition concentration scope of each medicament was determined in prerun, each medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament the crop germ.Measure colony diameter with the right-angled intersection method behind the 72h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active component glyoxalin and B (carbendazim, thiophanate-methyl, probenazole, Prochloraz, press down mould azoles, fluorine bacterium azoles) shared ratio in combination;
A is a glyoxalin;
B is carbendazim, thiophanate-methyl, probenazole, Prochloraz, press down a kind of in mould azoles, the fluorine bacterium azoles.
Application Example two:
Glyoxalin and carbendazim are composite to the pear scab Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining glyoxalin, carbendazim active compound and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 1 glyoxalin, carbendazim and composite toxicity test analysis of results table thereof to pear scab
As shown in Table 1, glyoxalin, carbendazim are to the EC of pear scab
50Be respectively 0.78mg/L and 9.57mg/L.Glyoxalin and carbendazim proportioning were at 40: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that glyoxalin and carbendazim were mixed in the scope at 40: 1 to 1: 80 all shows synergistic effect, especially when the two proportioning during at 1: 1 to 1: 20, synergistic effect is more obviously outstanding, synergy ratio SR maximum when glyoxalin and carbendazim percentage by weight are 1: 10 wherein, synergistic effect is the most obvious.
Application Example three
Glyoxalin and thiophanate-methyl are composite to the powdery mildew of cucumber Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining glyoxalin, the former medicine of thiophanate-methyl and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 2 glyoxalin, thiophanate-methyl and composite toxicity test analysis of results table thereof to powdery mildew of cucumber
As shown in Table 2, glyoxalin, thiophanate-methyl are to the EC of powdery mildew of cucumber
50Be respectively 0.65mg/L and 6.78mg/L.Glyoxalin and thiophanate-methyl proportioning were at 40: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that glyoxalin and thiophanate-methyl were mixed in the scope at 40: 1 to 1: 80 all shows synergistic effect, especially when the two proportioning during at 1: 1 to 1: 20, synergistic effect is more obviously outstanding, synergy ratio SR maximum when glyoxalin and thiophanate-methyl percentage by weight are 1: 10 wherein, synergistic effect is the most obvious.
Application Example four
Glyoxalin and probenazole are composite to the anthracnose of grape Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining glyoxalin, the former medicine of probenazole and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 3 glyoxalin, probenazole and composite toxicity test analysis of results table thereof to anthracnose of grape
As shown in Table 3, glyoxalin, probenazole are to the EC of anthracnose of grape
50Be respectively 0.56mg/L and 1.94mg/L.Glyoxalin and probenazole proportioning were at 40: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that glyoxalin and probenazole were mixed in the scope at 40: 1 to 1: 80 all shows synergistic effect, especially when the two proportioning during at 1: 1 to 1: 16, synergistic effect is more obviously outstanding, synergy ratio SR maximum when glyoxalin and probenazole percentage by weight are 1: 4 wherein, synergistic effect is the most obvious.
Application Example five:
Glyoxalin and Prochloraz are composite to the apple anthracnose Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining glyoxalin, the former medicine of Prochloraz and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 4 glyoxalin, Prochloraz and composite toxicity test analysis of results table thereof to apple anthracnose
As shown in Table 4, glyoxalin, Prochloraz are to the EC of apple anthracnose
50Be respectively 0.51mg/L and 1.86mg/L.Glyoxalin and Prochloraz proportioning were at 40: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that glyoxalin and Prochloraz were mixed in the scope at 40: 1 to 1: 80 all shows synergistic effect, synergy ratio SR maximum when glyoxalin and Prochloraz percentage by weight are 1: 4 wherein, synergistic effect is the most obvious.
Application Example six
Glyoxalin is with to press down mould azoles composite to the citrus scab Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: the process preliminary experiment is determined glyoxalin, is pressed down effective inhibition concentration scope of the former medicine of mould azoles and the two different proportioning mixture.
Toxicity test result
Table 5 glyoxalin, press down mould azoles and composite toxicity test analysis of results table thereof to citrus scab
As shown in Table 5, glyoxalin, press down the EC of mould azoles to citrus scab
50Be respectively 0.72mg/L and 2.83mg/L.Glyoxalin with press down mould azoles proportioning at 40: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, glyoxalin is described and presses down mould azoles and be mixed in the scope at 40: 1 to 1: 80 and all show synergistic effect, wherein when glyoxalin synergy ratio SR maximum when pressing down mould azoles percentage by weight and be 1: 4, synergistic effect is the most obvious.
Application Example seven
Glyoxalin and fluorine bacterium azoles are composite to the pear scab Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining glyoxalin, the former medicine of fluorine bacterium azoles and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 6 glyoxalin, fluorine bacterium azoles and composite toxicity test analysis of results table thereof to pear scab
As shown in Table 6, glyoxalin, fluorine bacterium azoles are to the EC of pear scab
50Be respectively 0.65mg/L and 0.74mg/L.Glyoxalin and fluorine bacterium azoles proportioning were at 40: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that glyoxalin and fluorine bacterium azoles were mixed in the scope at 40: 1 to 1: 80 all shows synergistic effect, especially when the two proportioning during at 10: 1 to 1: 10, synergistic effect is more obviously outstanding, synergy ratio SR maximum when glyoxalin and fluorine bacterium azoles percentage by weight are 1: 1 wherein, synergistic effect is the most obvious.
Application Example eight glyoxalins and carbendazim and the composite control pear scab test of pesticide effectiveness thereof
This experimental establishment is in Weinan City Pucheng County, Shaanxi Province, and test medicine is provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 5% glyoxalin wetting powder (commercial), 50% carbendazol wettable powder (commercial).
The investigation pear scab state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 7 days, 14 days after the dispenser for the second time.Experimental result is as follows:
Table 7 glyoxalin, carbendazim and the composite control pear scab test of pesticide effectiveness thereof
As can be seen from Table 7, can effectively prevent and treat pear scab after glyoxalin and carbendazim are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Application Example nine glyoxalins and thiophanate-methyl and the composite powdery mildew of cucumber test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is at Shaanxi Province's Weinan City Linwei District, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 5% glyoxalin wetting powder (commercial), 70% thiophanate-methyl wetting powder (commercial).
The preceding investigation of medicine powdery mildew of cucumber disease index, in the their early stage dispenser, dispenser for the second time after 10 days, dispenser is 2 times altogether, investigates disease indexs in 7 days, 14 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 8 glyoxalin, thiophanate-methyl and the composite powdery mildew of cucumber test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 8, can effectively prevent and treat powdery mildew of cucumber after glyoxalin and thiophanate-methyl are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Application Example ten glyoxalins and probenazole and the composite anthracnose of grape test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is at the Xian City, Shanxi Province Baqiao District, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 5% glyoxalin wetting powder (commercial), 42% probenazole suspending agent (commercial).
The investigation anthracnose of grape state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 7 days, 14 days after the dispenser for the second time.Experimental result is as follows:
Table 9 glyoxalin, probenazole and the composite anthracnose of grape test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 9, can effectively prevent and treat anthracnose of grape after glyoxalin and probenazole are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Application Example 11 glyoxalins and Prochloraz and the composite control apple anthracnose test of pesticide effectiveness thereof
This experimental establishment is at Shaanxi Province's Yan Luochuan County, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 5% glyoxalin wetting powder (commercial), 25% Prochloraz missible oil (commercial).
The preceding investigation of medicine apple anthracnose disease index, in the their early stage dispenser, dispenser for the second time after 10 days, dispenser is 2 times altogether, investigates disease indexs in 7 days, 14 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 10 glyoxalin, Prochloraz and the composite control apple anthracnose test of pesticide effectiveness thereof
As can be seen from Table 10, can effectively prevent and treat apple anthracnose after glyoxalin and Prochloraz are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Application Example ten diimine azoles and but the mould azoles and the composite citrus scab test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is in the Shimen County, Hunan Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, and contrast medicament 5% glyoxalin wetting powder (commercial), 50% presses down mould azoles missible oil (commercial).
The investigation citrus scab state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 7 days, 14 days after the dispenser for the second time.Experimental result is as follows:
Table 11 glyoxalin, press down the mould azoles and the composite citrus scab test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 11, glyoxalin with press down mould azoles and can effectively prevent and treat citrus scab after composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Application Example 13 glyoxalins and fluorine bacterium azoles and the composite control pear scab test of pesticide effectiveness thereof
This experimental establishment is in Weinan City Dengcheng County, Shaanxi Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 5% glyoxalin wetting powder (commercial), 30% triflumizole wettable powder (commercial).
The preceding investigation of medicine pear scab disease index, in the their early stage dispenser, dispenser for the second time after 10 days, dispenser is 2 times altogether, investigates disease indexs in 7 days, 14 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 12 glyoxalin, the composite control pear scab of the fluorine bacterium azoles test of pesticide effectiveness
As can be seen from Table 12, can effectively prevent and treat pear scab after glyoxalin and fluorine bacterium azoles are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Claims (10)
1. bactericidal composition that contains glyoxalin, it is characterized in that: the percentage by weight of A, two kinds of active components of B is 1～40%: 1～80%, described A component is a glyoxalin, and the B component is selected from carbendazim, thiophanate-methyl, probenazole, Prochloraz, presses down a kind of of mould azoles, fluorine bacterium azoles.
2. the bactericidal composition that contains glyoxalin according to claim 1 is characterized in that: wherein the percentage by weight of glyoxalin and effective active composition B is 1～35%: 5～70%.
3. the bactericidal composition that contains glyoxalin and carbendazim according to claim 2 is characterized in that: wherein the percentage by weight of glyoxalin and carbendazim is 5～30%: 10～60%.
4. the bactericidal composition that contains glyoxalin and thiophanate-methyl according to claim 2 is characterized in that: wherein the percentage by weight of glyoxalin and thiophanate-methyl is 5～30%: 10～60%.
5. the bactericidal composition that contains glyoxalin and probenazole according to claim 2 is characterized in that: wherein the percentage by weight of glyoxalin and probenazole is 5～30%: 10～50%.
6. the bactericidal composition that contains glyoxalin and Prochloraz according to claim 2 is characterized in that: wherein the percentage by weight of glyoxalin and Prochloraz is 5～30%: 10～50%.
7. glyoxalin and the bactericidal composition that presses down mould azoles of containing according to claim 2, it is characterized in that: wherein glyoxalin is 5～30%: 10～50% with the percentage by weight that presses down mould azoles.
8. the bactericidal composition that contains glyoxalin and fluorine bacterium azoles according to claim 2 is characterized in that: wherein the percentage by weight of glyoxalin and fluorine bacterium azoles is 5～30%: 5～40%.
9. the bactericidal composition that contains glyoxalin according to claim 1 is characterized in that: the formulation of microbicide compositions is selected from: wetting powder, water dispersible granules, suspending agent, suspension emulsion.
10. the bactericidal composition that contains glyoxalin according to claim 1 is used to prevent and treat crop scab, ring spot, spot defoliation, anthracnose, anthrachose of grape, shot hole, powdery mildew.
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| CN104886092A (en) * | 2012-09-11 | 2015-09-09 | 陕西美邦农药有限公司 | Pesticide composition containing penthiopyrad |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0306413A1 (en) * | 1987-09-03 | 1989-03-08 | Hokko Chemical Industry Co., Ltd | A synergistic fungicidal composition of agricultural and horticultural utilities, and methods for controlling fungal diseases on plants |
| CN1238126A (en) * | 1998-06-04 | 1999-12-15 | 许浩坤 | Wettable powder of triadimefon |
| HUP0104528A2 (en) * | 2001-10-26 | 2003-10-28 | VET-PHARMA Állatgyógyászati és Vegyipari Termékeket Gyártó és Forgalmazó Korlátolt Felelősségű Társaság | Biocidial benzimidazole or azole derivatives, preparation and use thereof |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0306413A1 (en) * | 1987-09-03 | 1989-03-08 | Hokko Chemical Industry Co., Ltd | A synergistic fungicidal composition of agricultural and horticultural utilities, and methods for controlling fungal diseases on plants |
| CN1238126A (en) * | 1998-06-04 | 1999-12-15 | 许浩坤 | Wettable powder of triadimefon |
| HUP0104528A2 (en) * | 2001-10-26 | 2003-10-28 | VET-PHARMA Állatgyógyászati és Vegyipari Termékeket Gyártó és Forgalmazó Korlátolt Felelősségű Társaság | Biocidial benzimidazole or azole derivatives, preparation and use thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104886092A (en) * | 2012-09-11 | 2015-09-09 | 陕西美邦农药有限公司 | Pesticide composition containing penthiopyrad |
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Effective date of registration: 20180116 Address after: 253411 West Cao village, Ningjin County, Dezhou City, Shandong Province, No. 87 Patentee after: Wang Jinhua Address before: 715500 Pucheng County of Shaanxi Province agricultural base industrial park Patentee before: Shaanxi Meibang Pesticide Co., Ltd. |
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