CN102057273B - 用于检测化学或生物成分的方法以及用于此的电极布置 - Google Patents

用于检测化学或生物成分的方法以及用于此的电极布置 Download PDF

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Publication number
CN102057273B
CN102057273B CN200980121017.XA CN200980121017A CN102057273B CN 102057273 B CN102057273 B CN 102057273B CN 200980121017 A CN200980121017 A CN 200980121017A CN 102057273 B CN102057273 B CN 102057273B
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electrode
molecule
electrodes
molecules
redox
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CN102057273A (zh
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E·内柏林
J·阿伯斯
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Fraunhofer Gesellschaft zur Foerderung der Angewandten Forschung eV
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Fraunhofer Gesellschaft zur Foerderung der Angewandten Forschung eV
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3277—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a redox reaction, e.g. detection by cyclic voltammetry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/403—Cells and electrode assemblies
    • G01N27/404—Cells with anode, cathode and cell electrolyte on the same side of a permeable membrane which separates them from the sample fluid, e.g. Clark-type oxygen sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/48—Systems using polarography, i.e. measuring changes in current under a slowly-varying voltage
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/30—Electrochemically active labels

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Electrochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN200980121017.XA 2008-06-06 2009-05-29 用于检测化学或生物成分的方法以及用于此的电极布置 Active CN102057273B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102008027038.5 2008-06-06
DE102008027038A DE102008027038A1 (de) 2008-06-06 2008-06-06 Verfahren zum Detektieren von chemischen oder biologischen Species sowie Elektrodenanordnung hierfür
PCT/EP2009/056616 WO2009147093A1 (de) 2008-06-06 2009-05-29 Verfahren zum detektieren von chemischen oder biologischen species sowie elektrodenanordnung hierfür

Publications (2)

Publication Number Publication Date
CN102057273A CN102057273A (zh) 2011-05-11
CN102057273B true CN102057273B (zh) 2015-09-23

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Country Link
US (1) US8900440B2 (enExample)
EP (1) EP2286227B1 (enExample)
JP (1) JP5675594B2 (enExample)
CN (1) CN102057273B (enExample)
DE (1) DE102008027038A1 (enExample)
WO (1) WO2009147093A1 (enExample)

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JP2011179893A (ja) * 2010-02-26 2011-09-15 Jfe Steel Corp 金属内部への侵入水素量の測定方法および移動体の金属部位内部へ侵入する水素量のモニタリング方法
ES2410754T3 (es) * 2010-05-25 2013-07-03 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Procedimiento para la detección electroquímica de reacciones de unión
DE102010064251A1 (de) 2010-12-28 2012-06-28 Robert Bosch Gmbh Handmessgerät zum Nachweis von verdeckten Schimmelschäden in Innenräumen
JP5754566B2 (ja) * 2011-08-26 2015-07-29 Ｊｆｅスチール株式会社 金属内部への侵入水素量の測定装置
JP5700673B2 (ja) * 2011-08-26 2015-04-15 Ｊｆｅスチール株式会社 金属内部への侵入水素量の測定方法および移動体の金属部位内部へ侵入する水素量のモニタリング方法
JP5777098B2 (ja) * 2011-08-26 2015-09-09 Ｊｆｅスチール株式会社 金属内部への侵入水素量の測定方法および移動体の金属部位内部へ侵入する水素量のモニタリング方法
CN103175872A (zh) * 2011-12-23 2013-06-26 长沙中生众捷生物技术有限公司 便携式电化学检测试纸条及其制备方法
KR101364647B1 (ko) 2012-03-14 2014-02-21 한국수력원자력 주식회사 고농도 비수용액 전해질에 적용가능한 금속이온 또는 산소이온의 모니터링 방법
DE102012205171B3 (de) 2012-03-29 2013-09-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Integriertes Einweg-Chipkartuschensystem für mobile Multiparameteranalysen chemischer und/oder biologischer Substanzen
GB201207869D0 (en) * 2012-05-04 2012-06-20 Accunostics Ltd Pulsed signal testing of biological fluid
JP5781256B2 (ja) * 2012-06-28 2015-09-16 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドＳｉｅｍｅｎｓ Ｈｅａｌｔｈｃａｒｅ Ｄｉａｇｎｏｓｔｉｃｓ Ｉｎｃ． リーダー装置および信号増幅方法
DE102012018539A1 (de) 2012-09-19 2014-03-20 Seuffer Gmbh & Co.Kg Verfahren und Vorrichtung zur Erfassung von Eigenschaften fluider Medien
JP5979731B2 (ja) * 2014-01-08 2016-08-31 Ｊｆｅスチール株式会社 移動体の金属部位内部へ侵入する水素量のモニタリング方法
EP3498718B1 (en) 2014-04-23 2020-04-15 Terumo Kabushiki Kaisha Non-enzymatic electrochemical sensor for measuring analytes
JP6130447B2 (ja) * 2015-07-29 2017-05-17 Ｊｆｅスチール株式会社 移動体の金属部位内部へ侵入する水素量のモニタリング方法
US11119101B2 (en) 2017-01-13 2021-09-14 Taiwan Semiconductor Manufacturing Co., Ltd. Cartridge and analyzer for fluid analysis

Citations (2)

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JP2001512691A (ja) * 1997-08-12 2001-08-28 ユニバーシティ・オブ・サザン・カリフォルニア イムノアッセイ分析および分子生物学的な過程を調べるための電気化学的レポーターシステム
JP2003513274A (ja) * 1999-11-02 2003-04-08 アドバンスド センサー テクノロジーズ， インコーポレイテッド 電流滴定センサおよび電位差センサの微視的組み合わせ

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JPH04118554A (ja) 1989-12-28 1992-04-20 Tosoh Corp 電気化学的酵素測定方法およびバイオセンサ
DE4318519C2 (de) 1993-06-03 1996-11-28 Fraunhofer Ges Forschung Elektrochemischer Sensor
DE19610115C2 (de) 1996-03-14 2000-11-23 Fraunhofer Ges Forschung Detektion von Molekülen und Molekülkomplexen
DE19916867A1 (de) * 1999-04-14 2000-10-19 Fraunhofer Ges Forschung Anordnung und Verfahren zur Herstellung planarer Arrays mit immobilisierten Molekülen
US7455975B2 (en) * 2000-04-14 2008-11-25 Esa Biosciences, Inc. Electrochemical detection of nucleic acid sequences
WO2002082078A2 (en) 2001-04-09 2002-10-17 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. Activated enzyme-linked detection systems for detecting and quantifying nucleid acids, antigens antibodies and other analytes
EP1409728A2 (en) 2001-04-09 2004-04-21 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Non-enzymatic liposome-linked closely spaced array electrodes assay (nel-ela) for detecting and quantifying nucleic acids
WO2005073708A2 (de) 2004-01-29 2005-08-11 Siemens Aktiengesellschaft Verfahren zur messung der konzentration oder konzentrationsänderung einer redoxaktiven substanz und zugehörige vorrichtung
JP4007606B2 (ja) * 2004-02-03 2007-11-14 キヤノン株式会社 センサおよび検出方法
DE102005007539A1 (de) * 2005-02-17 2006-08-31 Universität Rostock Einrichtung zur Bestimmung redoxaktiver Stoffe
DE102005037436A1 (de) 2005-08-04 2007-02-15 Siemens Ag Verfahren und System zur Konzentrationsbestimmung eines Analyt-Enzym-Komplexes oder Analyt-Enzym-Konjugats, insbesondere zur elektrochemischen Detektion des Analyten, und zugehörige Messvorrichtung
DE202005020141U1 (de) * 2005-11-29 2007-01-11 Farco-Pharma Gmbh Detektionseinheit, insbesondere Biosensor
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Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
JP2001512691A (ja) * 1997-08-12 2001-08-28 ユニバーシティ・オブ・サザン・カリフォルニア イムノアッセイ分析および分子生物学的な過程を調べるための電気化学的レポーターシステム
JP2003513274A (ja) * 1999-11-02 2003-04-08 アドバンスド センサー テクノロジーズ， インコーポレイテッド 電流滴定センサおよび電位差センサの微視的組み合わせ

Also Published As

Publication number Publication date
EP2286227B1 (de) 2017-12-13
JP2011522266A (ja) 2011-07-28
WO2009147093A1 (de) 2009-12-10
DE102008027038A1 (de) 2009-12-17
US8900440B2 (en) 2014-12-02
CN102057273A (zh) 2011-05-11
EP2286227A1 (de) 2011-02-23
JP5675594B2 (ja) 2015-02-25
US20110156722A1 (en) 2011-06-30

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