CN102038606B - 冻干粉用镀膜胶塞的制造方法 - Google Patents
冻干粉用镀膜胶塞的制造方法 Download PDFInfo
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- CN102038606B CN102038606B CN201010548097A CN201010548097A CN102038606B CN 102038606 B CN102038606 B CN 102038606B CN 201010548097 A CN201010548097 A CN 201010548097A CN 201010548097 A CN201010548097 A CN 201010548097A CN 102038606 B CN102038606 B CN 102038606B
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- Prior art keywords
- plug
- lyophilized powder
- rubber stopper
- rubber
- neck
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008176 lyophilized powder Substances 0.000 title claims abstract description 36
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 15
- 239000011248 coating agent Substances 0.000 title abstract description 5
- 238000000576 coating method Methods 0.000 title abstract description 5
- 239000010409 thin film Substances 0.000 claims abstract description 19
- 238000000034 method Methods 0.000 claims abstract description 10
- 239000004033 plastic Substances 0.000 claims abstract description 10
- 229920003023 plastic Polymers 0.000 claims abstract description 10
- 239000010408 film Substances 0.000 claims description 24
- 239000003292 glue Substances 0.000 claims description 12
- 238000005516 engineering process Methods 0.000 claims description 8
- 239000000853 adhesive Substances 0.000 claims description 7
- 230000001070 adhesive effect Effects 0.000 claims description 7
- 238000013459 approach Methods 0.000 claims description 7
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 claims description 4
- 238000012856 packing Methods 0.000 claims description 2
- 238000007781 pre-processing Methods 0.000 claims description 2
- 230000001954 sterilising effect Effects 0.000 abstract description 4
- 238000004140 cleaning Methods 0.000 abstract description 2
- 239000002245 particle Substances 0.000 abstract description 2
- 238000004080 punching Methods 0.000 abstract 2
- 238000005987 sulfurization reaction Methods 0.000 abstract 2
- 239000003814 drug Substances 0.000 description 9
- 239000000463 material Substances 0.000 description 5
- 239000003242 anti bacterial agent Substances 0.000 description 4
- 229940088710 antibiotic agent Drugs 0.000 description 4
- 239000012528 membrane Substances 0.000 description 4
- 239000004531 microgranule Substances 0.000 description 4
- 238000000465 moulding Methods 0.000 description 4
- 238000009966 trimming Methods 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- 230000009102 absorption Effects 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 230000008014 freezing Effects 0.000 description 2
- 238000007710 freezing Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000013508 migration Methods 0.000 description 2
- 230000005012 migration Effects 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 229920002799 BoPET Polymers 0.000 description 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003749 cleanliness Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 238000011086 high cleaning Methods 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000009512 pharmaceutical packaging Methods 0.000 description 1
- 229920000052 poly(p-xylylene) Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000012797 qualification Methods 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
Description
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201010548097A CN102038606B (zh) | 2010-11-17 | 2010-11-17 | 冻干粉用镀膜胶塞的制造方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201010548097A CN102038606B (zh) | 2010-11-17 | 2010-11-17 | 冻干粉用镀膜胶塞的制造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102038606A CN102038606A (zh) | 2011-05-04 |
CN102038606B true CN102038606B (zh) | 2012-10-24 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201010548097A Active CN102038606B (zh) | 2010-11-17 | 2010-11-17 | 冻干粉用镀膜胶塞的制造方法 |
Country Status (1)
Country | Link |
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CN (1) | CN102038606B (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104908187A (zh) * | 2015-06-30 | 2015-09-16 | 江苏博生医用新材料股份有限公司 | 一种新型复合结构药用瓶塞及其制造方法 |
CN114213774A (zh) * | 2021-12-14 | 2022-03-22 | 湖北华强科技股份有限公司 | 一种双叉结构冻干局部覆膜胶塞的制备方法 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4441621A (en) * | 1981-08-24 | 1984-04-10 | Takeda Chemical Industries, Ltd. | Pierceable closure member for vial |
CN1699044A (zh) * | 2005-06-13 | 2005-11-23 | 盛州橡塑胶(苏州)有限公司 | 镀膜胶塞的二次成型方法 |
CN201192883Y (zh) * | 2008-03-27 | 2009-02-11 | 江阴兰陵瓶塞有限公司 | 一种药用胶塞硫化装置 |
CN201299783Y (zh) * | 2008-10-30 | 2009-09-02 | 江苏润德医用材料有限公司 | 冻干粉胶塞 |
CN201542944U (zh) * | 2009-11-23 | 2010-08-11 | 湖北华强科技有限责任公司 | 医药用橡胶冻干隔膜瓶塞 |
CN101797789A (zh) * | 2009-09-22 | 2010-08-11 | 欧阳雷 | 一种形状自适应模内装饰的方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH1094581A (ja) * | 1996-07-31 | 1998-04-14 | Daikyo Seiko:Kk | 医薬品容器用ゴム栓 |
-
2010
- 2010-11-17 CN CN201010548097A patent/CN102038606B/zh active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4441621A (en) * | 1981-08-24 | 1984-04-10 | Takeda Chemical Industries, Ltd. | Pierceable closure member for vial |
CN1699044A (zh) * | 2005-06-13 | 2005-11-23 | 盛州橡塑胶(苏州)有限公司 | 镀膜胶塞的二次成型方法 |
CN201192883Y (zh) * | 2008-03-27 | 2009-02-11 | 江阴兰陵瓶塞有限公司 | 一种药用胶塞硫化装置 |
CN201299783Y (zh) * | 2008-10-30 | 2009-09-02 | 江苏润德医用材料有限公司 | 冻干粉胶塞 |
CN101797789A (zh) * | 2009-09-22 | 2010-08-11 | 欧阳雷 | 一种形状自适应模内装饰的方法 |
CN201542944U (zh) * | 2009-11-23 | 2010-08-11 | 湖北华强科技有限责任公司 | 医药用橡胶冻干隔膜瓶塞 |
Non-Patent Citations (1)
Title |
---|
JP特开平10-94581A 1998.04.14 |
Also Published As
Publication number | Publication date |
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CN102038606A (zh) | 2011-05-04 |
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PB01 | Publication | ||
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Manufacturing method of coated rubber plug for lyophilized powder Effective date of registration: 20220725 Granted publication date: 20121024 Pledgee: Lai An county Jinan financing Company limited by guarantee Pledgor: ANHUI HUAFENG PHARMACEUTICAL RUBBER Co.,Ltd. Registration number: Y2022980011140 |
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PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Granted publication date: 20121024 Pledgee: Lai An county Jinan financing Company limited by guarantee Pledgor: ANHUI HUAFENG PHARMACEUTICAL RUBBER Co.,Ltd. Registration number: Y2022980011140 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Manufacturing method of coating stopper for freeze-dried powder Granted publication date: 20121024 Pledgee: Anhui Laian Rural Commercial Bank Co.,Ltd. Pledgor: ANHUI HUAFENG PHARMACEUTICAL RUBBER Co.,Ltd. Registration number: Y2024980016919 |
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PE01 | Entry into force of the registration of the contract for pledge of patent right |