CN102038001B - Azadirachtin and bacillus subtilis mixed water dispersible granule - Google Patents
Azadirachtin and bacillus subtilis mixed water dispersible granule Download PDFInfo
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- CN102038001B CN102038001B CN201010572445.9A CN201010572445A CN102038001B CN 102038001 B CN102038001 B CN 102038001B CN 201010572445 A CN201010572445 A CN 201010572445A CN 102038001 B CN102038001 B CN 102038001B
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Abstract
The invention discloses an azadirachtin and bacillus subtilis mixed water dispersible granule consisting the following substances in percentage by weight: 0.1-50% azadirachtin, 1-30% wetting agent, 5-30% binder, 0.1-30% disintegrant, 10-60% carriers. The invention belongs to the field of biopesticide, can prevent the drug resistance of pests, improve the application effect of the water dispersible granule, prevent various agriculture and forestry diseases, widen the application range of the water dispersible granule by utilizing the synergy relationship between the active component azadirachtin and the bacillus subtilis specifically; moreover, the water dispersible granule has no pollution or residue, high efficiency and low toxin; therefore, the water dispersible granule is beneficial to the ecological environment protection and the safety of people and animals.
Description
Technical field
The present invention relates to a kind of agriculture mixture water dispersible granules, specifically refer to a kind of nimbin and bacillus subtilis mixture water dispersible granules.
Background technology
At present, agriculturally use chemical pesticide medicament in a large number, due to its toxic and side effect, all bring harm greatly and many negative effects to the protection of the mankind, livestock and natural environment.As Long-Time Service can cause person poultry poisoning, manslaughters a large amount of useful natural enemy, destroy the series of problems such as ecotope.The chemical pesticide of a certain type of Long-Time Service, insect is easy to develop immunity to drugs, thus causes the amount of application of chemical pesticide sharply to increase, vicious circle like this, greatly increase on the one hand the financial burden of peasant, on the other hand severe contamination crop ecological environment.
Many developed countries and regions have started to forbid promoting the use of chemical agent, in order to reduce the usage ratio of chemical pesticide as far as possible, make great efforts development and apply the Main way that biopesticide has become Developing China green agriculture.
Summary of the invention
The object of the invention is to the deficiency overcoming traditional farming preparation, a kind of water dispersible granules is disclosed, after rational mixture is carried out to nimbin and bacillus subtilis, there is provided one can prevent and treat multiple agricultural disease, expanding prevention is composed, and reduces nimbin and the bacillus subtilis mixture water dispersible granules of pesticidal preparations consumption.
The present invention is achieved through the following technical solutions: a kind of nimbin and bacillus subtilis mixture water dispersible granules, this water dispersible granules contains the material of following percentage by weight: 0.1% ~ 50% nimbin, 0.1% ~ 50% bacillus subtilis, 1% ~ 30% wetting agent, 5 ~ 30% binding agents, 0.1% ~ 30% disintegrant, 10% ~ 60% carrier.
Preferred as one, this nimbin and bacillus subtilis mixture water dispersible granules contain the material of following percentage by weight: 0.1% ~ 20% nimbin, 0.1% ~ 20% bacillus subtilis, 1% ~ 30% wetting agent, 5% ~ 30% binding agent, 0.1% ~ 30% disintegrant, 10% ~ 60% carrier.
Preferred as one, this nimbin and bacillus subtilis mixture water dispersible granules contain the material of following percentage by weight: 0.3% ~ 10% nimbin, 1% ~ 10% bacillus subtilis, 5% ~ 20% wetting agent, 10% ~ 25% binding agent, 10% ~ 25% disintegrant, 30% ~ 60% carrier.
Preferred as one, this nimbin and bacillus subtilis mixture water dispersible granules contain the material of following percentage by weight: 0.3% nimbin, 0.8% bacillus subtilis, 10% wetting agent, 10% binding agent, 20% disintegrant, 58.9% carrier.
Described wetting agent is preferably castor oil polyoxyethylene ether, sucrose ester, tween, sodium alkylether sulphate, alkylbenzenesulfonate, pulls open any one or more compound in powder, multi-sorbitol ester, and when using multiple, total usage amount can not be greater than the maximum of deal.
Described binding agent is preferably any one or more compound in starch, methylcellulose, sodium carboxymethylcellulose, hydroxypropyl methylcellulose, polyvinylpyrrolidone, and when using multiple, total usage amount can not be greater than the maximum of deal.
Described disintegrant is preferably any one or more compound in crospolyvinylpyrrolidone, low substituted hydroxy-propyl methylcellulose, dried starch, sodium carboxymethyl starch, gas-producing disintegrant, and when using multiple, total usage amount can not be greater than the maximum of deal.
Described carrier be in sliding clay, vermiculite, fine particle calcium carbonate, white carbon, bentonite one or more, when using multiple, total usage amount can not be greater than the maximum of deal.
The present invention compared with prior art, has the following advantages and beneficial effect:
(1) nimbin and bacillus subtilis are collaborative plays a role, and has remarkable result especially, be also suitable for preventing from producing serious drug-fast multiclass disease simultaneously to root nodule germ, Pyricularia oryzae and crop powdery mildew, gray mold.
(2) nimbin and bacillus subtilis mixture water dispersible granules is adopted, determine the mixed ratio obtaining good bactericidal effect, reduce consumption and the persticide residue of nimbin, environmentally safe, noresidue, efficiently, low toxicity, pest resistance to insecticide can be delayed simultaneously and produce.
(3) alleviating the toxic and side effect to using crop, being conducive to protecting person poultry safety, preserving the ecological environment.
Embodiment
Below in conjunction with preferred embodiment, the present invention is described in further detail, and wetting agent, binding agent, disintegrant, carrier can refer to this area routine and use, and therefore invention are not defined in following embodiment.
Embodiment 1
Production concentration is nimbin and the bacillus subtilis mixture water dispersible granules of 1.1%, and each component proportion is:
(1) 0.3% (weight) nimbin is added;
(2) 0.8% (weight) bacillus subtilis is added;
(3) adding 10% (weight) tween is wetting agent;
(4) adding 10% (weight) hydroxypropyl methylcellulose is binding agent;
(5) adding 20% (weight) dried starch is disintegrant;
(6) adding 58.9% (weight) vermiculite is carrier;
Namely granulation after formulation material mixture is carried out ultra-fine grinding, drying, screening obtain product.
Embodiment 2
Production concentration is nimbin and the bacillus subtilis mixture water dispersible granules of 18%, and each component proportion is:
(1) 10% (weight) nimbin is added;
(2) 8% (weight) bacillus subtilis is added;
(3) adding 12% (weight) sucrose ester is wetting agent;
(4) adding 13% (weight) methylcellulose is binding agent;
(5) adding 15% (weight) sodium carboxymethyl starch is disintegrant;
(6) adding 42% (weight) white carbon is carrier;
Namely granulation after formulation material mixture is carried out ultra-fine grinding, drying, screening obtain product.
Embodiment 3
Production concentration is nimbin and the bacillus subtilis mixture water dispersible granules of 10.1%, and each component proportion is:
(1) 0.1% (weight) nimbin is added;
(2) 10% (weight) bacillus subtilis is added;
(3) adding 12% (weight) sodium alkylether sulphate is wetting agent;
(4) adding 18% (weight) starch is binding agent;
(5) adding 20% (weight) sodium carboxymethyl starch is disintegrant;
(6) adding 39.9% (weight) fine particle calcium carbonate is carrier;
Namely granulation after formulation material mixture is carried out ultra-fine grinding, drying, screening obtain product.
Embodiment 4
Production concentration is nimbin and the bacillus subtilis mixture water dispersible granules of 50.3%, and each component proportion is:
(1) 0.3% (weight) nimbin is added;
(2) 50% (weight) bacillus subtilis is added;
(3) adding 11% (weight) sodium alkylether sulphate is wetting agent;
(4) adding 10% (weight) starch is binding agent;
(5) adding 10% (weight) low substituted hydroxy-propyl Methyl cellulose is disintegrant;
(6) adding 18.7% (weight) bentonite is carrier;
Namely granulation after formulation material mixture is carried out ultra-fine grinding, drying, screening obtain product.
Embodiment 5
Production concentration is nimbin and the bacillus subtilis mixture water dispersible granules of 51%, and each component proportion is:
(1) 50% (weight) nimbin is added;
(2) 1% (weight) bacillus subtilis is added;
(3) adding 11% (weight) sodium alkylether sulphate is wetting agent;
(4) adding 13% (weight) starch is binding agent;
(5) adding 10% (weight) low substituted hydroxy-propyl Methyl cellulose is disintegrant;
(6) adding 15% (weight) bentonite is carrier;
Namely granulation after formulation material mixture is carried out ultra-fine grinding, drying, screening obtain product.
The test effect of nimbin and bacillus subtilis mixture water dispersible granules:
Test method 1: after the nimbin bacillus subtilis water dispersible granules of production 3% is diluted to 800 times, 1000 times, 1600 times, field gray mold of cucumber, powdery mildew of cucumber, Cruciferae club root are prevented and treated, the incidence of 5 point samplings to crop pest is adopted to make investigation, the result of getting 3 repeated tests is added up, and statistics is in table 1.
Table 1 nimbin and bacillus subtilis mixture water dispersible granules field sterilizing ability measure
As can be seen from Table 1, nimbin and bacillus subtilis mixture water dispersible granules are comparatively used alone nimbin emulsion or bacillus subtilis bacterial emulsion, obviously can reduce the incidence of field gray mold of cucumber, powdery mildew of cucumber, Cruciferae club root, the control for such crop germ has notable synergistic effect.
Test method 2: nimbin the present invention prepared and bacillus subtilis mixture water dispersible granules are mixed with the preparation that concentration is 95%, and be diluted to 1ppm Toxicity Determination is carried out to powdery mildew pathogenic bacteria, bacteriostasis rate reaches 94%; Being used alone the 1ppm liquor bacteriostasis rate that the former medicine of bacillus subtilis is mixed with is 83%; Being used alone the 1ppm liquor bacteriostasis rate that nimbin raw medicine is mixed with is 35%; The bacteriostasis rate of control group acetone is 12%.
As can be seen here, nimbin and bacillus subtilis mixture water dispersible granules are comparatively used alone nimbin raw medicine or the former medicine Be very effective of bacillus subtilis for the preventive and therapeutic effect of powdery mildew, possess good synergistic effect.
Claims (6)
1. a nimbin and bacillus subtilis mixture water dispersible granules, it is characterized in that, this water dispersible granules contains the material of following percentage by weight: 1% nimbin, 2% bacillus subtilis, 1% ~ 30% wetting agent, 5 ~ 30% binding agents, 0.1% ~ 30% disintegrant, 10% ~ 60% carrier.
2. a nimbin and bacillus subtilis mixture water dispersible granules, it is characterized in that, this water dispersible granules contains the material of following percentage by weight: 0.3% nimbin, 0.8% bacillus subtilis, 1% ~ 30% wetting agent, 5 ~ 30% binding agents, 0.1% ~ 30% disintegrant, 10% ~ 60% carrier.
3. a nimbin and bacillus subtilis mixture water dispersible granules, it is characterized in that, this water dispersible granules contains the material of following percentage by weight: 10% nimbin, 8% bacillus subtilis, 1% ~ 30% wetting agent, 5 ~ 30% binding agents, 0.1% ~ 30% disintegrant, 10% ~ 60% carrier.
4. a nimbin and bacillus subtilis mixture water dispersible granules, it is characterized in that, this water dispersible granules contains the material of following percentage by weight: 0.1% nimbin, 10% bacillus subtilis, 1% ~ 30% wetting agent, 5 ~ 30% binding agents, 0.1% ~ 30% disintegrant, 10% ~ 60% carrier.
5. a nimbin and bacillus subtilis mixture water dispersible granules, it is characterized in that, this water dispersible granules contains the material of following percentage by weight: 0.3% nimbin, 50% bacillus subtilis, 1% ~ 30% wetting agent, 5 ~ 30% binding agents, 0.1% ~ 30% disintegrant, 10% ~ 60% carrier.
6. a nimbin and bacillus subtilis mixture water dispersible granules, it is characterized in that, this water dispersible granules contains the material of following percentage by weight: 50% nimbin, 1% bacillus subtilis, 1% ~ 30% wetting agent, 5 ~ 30% binding agents, 0.1% ~ 30% disintegrant, 10% ~ 60% carrier.
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| CN201010572445.9A CN102038001B (en) | 2010-12-03 | 2010-12-03 | Azadirachtin and bacillus subtilis mixed water dispersible granule |
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| CN201010572445.9A CN102038001B (en) | 2010-12-03 | 2010-12-03 | Azadirachtin and bacillus subtilis mixed water dispersible granule |
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| CN102038001B true CN102038001B (en) | 2014-12-31 |
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Cited By (1)
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| EP3141242B1 (en) * | 2015-09-11 | 2024-04-10 | Symrise AG | Oral dosage form |
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| CN103563991A (en) * | 2012-07-31 | 2014-02-12 | 江苏丘陵地区镇江农业科学研究所 | Preparation method of brevibacillus brevis water dispersible granules |
| CN103990117A (en) * | 2014-04-25 | 2014-08-20 | 珠海市康益达生物科技有限公司 | Nuisance-free antibiotic insecticidal preparation for aquatic product culturing, and preparation method thereof |
| CN106719838A (en) * | 2016-11-22 | 2017-05-31 | 恒大园林集团有限公司 | A kind of complex ecological agricultural chemicals and preparation method thereof |
| CN106665259A (en) * | 2017-01-12 | 2017-05-17 | 恒大园林集团有限公司 | Real estate garden maintenance and management method |
| CN109329317A (en) * | 2018-11-24 | 2019-02-15 | 衡阳市富农科技有机农产品供销专业合作社 | A kind of plant insecticide of type water dispersable granules and preparation method thereof |
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| GB8805394D0 (en) * | 1988-03-07 | 1988-04-07 | Agricultural Genetics Co | Antibiotic |
| US5356628A (en) * | 1989-12-26 | 1994-10-18 | W. R. Grace & Co.-Conn. | Hydrophobic extracted neem oil-a novel fungicide |
| JP3554592B2 (en) * | 1994-12-20 | 2004-08-18 | 出光興産株式会社 | Bacillus spore fraction and plant disease control method using the spore fraction |
| CN1256878C (en) * | 2002-10-09 | 2006-05-24 | 华南农业大学 | Nimbin and antibiotic bacteriocide mixed pesticide preparation |
| CN1589631A (en) * | 2003-08-29 | 2005-03-09 | 郭伟光 | Compound insecticide of bacillus thuringiensis, muscardine and meliaceae and its preparation method |
| CN101513194B (en) * | 2009-03-10 | 2011-08-17 | 华南农业大学 | Compound desinsection primary agent and pesticide consisting of verticillium lecanii and nimbin |
| CN101773149B (en) * | 2010-02-10 | 2012-02-22 | 山东泰丰源生物科技有限公司 | Bacillus subtilis Bs-03 wettable powder preparation and water-dispersing granule preparation |
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| EP3141242B1 (en) * | 2015-09-11 | 2024-04-10 | Symrise AG | Oral dosage form |
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Application publication date: 20110504 Assignee: Chengdu Lujin Biological Science & Technology Co., Ltd. Assignor: Chengdu Greengold High-Tech Co., Ltd. Contract record no.: 2016510000034 Denomination of invention: Azadirachtin and bacillus subtilis mixed water dispersible granule Granted publication date: 20141231 License type: Exclusive License Record date: 20161213 |
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