CN102028944B - 含有低剂量hib偶联物的组合疫苗 - Google Patents
含有低剂量hib偶联物的组合疫苗 Download PDFInfo
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- CN102028944B CN102028944B CN2010105870900A CN201010587090A CN102028944B CN 102028944 B CN102028944 B CN 102028944B CN 2010105870900 A CN2010105870900 A CN 2010105870900A CN 201010587090 A CN201010587090 A CN 201010587090A CN 102028944 B CN102028944 B CN 102028944B
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/099—Bordetella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0405787.3A GB0405787D0 (en) | 2004-03-15 | 2004-03-15 | Low dose vaccines |
| GB0405787.3 | 2004-03-15 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2005800152906A Division CN1968711B (zh) | 2004-03-15 | 2005-03-14 | 含有低剂量hib偶联物的组合疫苗 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102028944A CN102028944A (zh) | 2011-04-27 |
| CN102028944B true CN102028944B (zh) | 2013-12-04 |
Family
ID=32117706
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010105870900A Expired - Fee Related CN102028944B (zh) | 2004-03-15 | 2005-03-14 | 含有低剂量hib偶联物的组合疫苗 |
| CN2005800152906A Expired - Fee Related CN1968711B (zh) | 2004-03-15 | 2005-03-14 | 含有低剂量hib偶联物的组合疫苗 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2005800152906A Expired - Fee Related CN1968711B (zh) | 2004-03-15 | 2005-03-14 | 含有低剂量hib偶联物的组合疫苗 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20090208526A1 (enExample) |
| EP (1) | EP1725258B1 (enExample) |
| JP (2) | JP4954056B2 (enExample) |
| CN (2) | CN102028944B (enExample) |
| AT (1) | ATE480257T1 (enExample) |
| BR (1) | BRPI0508813B8 (enExample) |
| CA (1) | CA2559996C (enExample) |
| DE (1) | DE602005023422D1 (enExample) |
| DK (1) | DK1725258T3 (enExample) |
| GB (1) | GB0405787D0 (enExample) |
| RU (1) | RU2435609C2 (enExample) |
| SG (1) | SG151253A1 (enExample) |
| WO (1) | WO2005089794A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100898845B1 (ko) * | 2000-06-29 | 2009-05-21 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 다가 백신 조성물 |
| GB0505518D0 (en) * | 2005-03-17 | 2005-04-27 | Chiron Srl | Combination vaccines with whole cell pertussis antigen |
| KR101359953B1 (ko) | 2005-06-27 | 2014-02-21 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 면역원성 조성물 |
| CN103585624A (zh) | 2006-09-07 | 2014-02-19 | 葛兰素史密丝克莱恩生物有限公司 | 疫苗 |
| GB0700135D0 (en) * | 2007-01-04 | 2007-02-14 | Glaxosmithkline Biolog Sa | Vaccine |
| WO2008149238A2 (en) * | 2007-06-04 | 2008-12-11 | Novartis Ag | Formulation of meningitis vaccines |
| CU23652A1 (es) * | 2007-06-29 | 2011-05-27 | Centro Inmunologia Molecular | Composición vacunal homogénea para el tratamiento del cáncer y su método de obtención |
| EP2457590B1 (en) * | 2008-05-01 | 2014-12-24 | Arecor Limited | Protein formulation |
| PE20100365A1 (es) | 2008-10-24 | 2010-05-21 | Panacea Biotec Ltd | Novedosas vacunas de combinacion con tos ferina de celulas enteras y metodo para su elaboracion |
| PE20100366A1 (es) | 2008-10-24 | 2010-05-21 | Panacea Biotec Ltd | Novedosas composiciones de vacuna con tos ferina acelular asi como el metodo para su elaboracion |
| GB0822633D0 (en) * | 2008-12-11 | 2009-01-21 | Novartis Ag | Formulation |
| NZ598654A (en) | 2009-09-02 | 2014-05-30 | Novartis Ag | Immunogenic compositions including tlr activity modulators |
| BR112012014689B1 (pt) * | 2009-12-16 | 2019-11-12 | Serum Institute Of India Private Limited | composição imunogênica |
| CN105999275A (zh) | 2010-09-01 | 2016-10-12 | 诺华有限公司 | 免疫增强剂吸附不溶性金属离子 |
| WO2012117377A1 (en) * | 2011-03-02 | 2012-09-07 | Novartis Ag | Combination vaccines with lower doses of antigen and/or adjuvant |
| AU2012245198B2 (en) * | 2011-04-21 | 2017-07-13 | Trustees Of Tufts College | Compositions and methods for stabilization of active agents |
| RU2014140521A (ru) | 2012-03-08 | 2016-04-27 | Новартис Аг | Адъювантные составы бустерных вакцин |
| PL2911676T3 (pl) * | 2012-10-29 | 2020-12-28 | The Board Of Trustees Of The University Of Arkansas | Nowe adiuwanty śluzówkowe oraz systemy dostarczania |
| RU2626532C2 (ru) * | 2015-01-16 | 2017-07-28 | Федеральное государственное унитарное предприятие "Научно-производственное объединение по медицинским иммунобиологическим препаратам "Микроген" Министерства здравоохранения Российской Федерации | Комбинированная вакцина для профилактики коклюша, дифтерии, столбняка, гепатита в и инфекции, вызываемой haemophilus influenzae тип в |
| US11027005B2 (en) * | 2016-10-20 | 2021-06-08 | Km Biologics Co., Ltd. | Method for producing Hib conjugate vaccine using PRP with lowered molecular weight |
| JP7404226B2 (ja) | 2017-07-18 | 2023-12-25 | セラム インスティテュート オブ インディア プライベート リミティド | 向上した安定性、高度の免疫原性、及び減少した反応源性を有する免疫原性組成物、並びにその調製プロセス |
| CN110251667A (zh) * | 2018-05-11 | 2019-09-20 | 武汉博沃生物科技有限公司 | 一种免疫组合制剂及其制备方法和应用 |
| JOP20190242A1 (ar) | 2018-10-12 | 2020-04-12 | Serum Institute Of India Pvt Ltd | تركيبة لقاح توليفي تشمل فيروس شلل الأطفال ذو جرعة مخفّضة خاملة التنشيط وطريقة لتحضيرها |
| WO2021176409A1 (en) | 2020-03-05 | 2021-09-10 | Sanofi Healthcare India Private Limited | Preservative combination for vaccine composition |
| CN118903397A (zh) * | 2024-10-12 | 2024-11-08 | 成都迈科康生物科技有限公司 | GloboH六糖、linker化合物、蛋白偶联物及免疫原性组合物在治疗或抑制上皮性肿瘤中的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2734484B1 (fr) * | 1995-05-24 | 1997-06-27 | Pasteur Merieux Serums Vacc | Composition vaccinale liquide et procede de fabrication |
| US20020054884A1 (en) * | 1995-06-23 | 2002-05-09 | Smithkline Beecham Biologicals, Sa | Vaccine composition comprising a polysaccharide conjugate antigen adsorbed onto aluminium phosphate |
| EP0833662B2 (en) * | 1995-06-23 | 2011-01-26 | SmithKline Beecham Biologicals S.A. | A vaccine composition comprsing a Haemophilus influenzae B polysaccharide conjugate antigen adsorbed onto aluminium phosphate |
| KR100898845B1 (ko) * | 2000-06-29 | 2009-05-21 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 다가 백신 조성물 |
-
2004
- 2004-03-15 GB GBGB0405787.3A patent/GB0405787D0/en not_active Ceased
-
2005
- 2005-03-14 BR BRPI0508813A patent/BRPI0508813B8/pt active IP Right Grant
- 2005-03-14 SG SG200901653-6A patent/SG151253A1/en unknown
- 2005-03-14 US US10/593,007 patent/US20090208526A1/en not_active Abandoned
- 2005-03-14 DE DE602005023422T patent/DE602005023422D1/de not_active Expired - Lifetime
- 2005-03-14 RU RU2006136212/15A patent/RU2435609C2/ru not_active IP Right Cessation
- 2005-03-14 AT AT05727218T patent/ATE480257T1/de not_active IP Right Cessation
- 2005-03-14 JP JP2007503444A patent/JP4954056B2/ja not_active Expired - Fee Related
- 2005-03-14 CA CA2559996A patent/CA2559996C/en not_active Expired - Fee Related
- 2005-03-14 EP EP05727218A patent/EP1725258B1/en not_active Expired - Lifetime
- 2005-03-14 CN CN2010105870900A patent/CN102028944B/zh not_active Expired - Fee Related
- 2005-03-14 CN CN2005800152906A patent/CN1968711B/zh not_active Expired - Fee Related
- 2005-03-14 WO PCT/IB2005/000927 patent/WO2005089794A2/en not_active Ceased
- 2005-03-14 DK DK05727218.9T patent/DK1725258T3/da active
-
2008
- 2008-03-06 JP JP2008056997A patent/JP2008150397A/ja active Pending
-
2011
- 2011-09-30 US US13/250,094 patent/US9259460B2/en active Active
Non-Patent Citations (3)
| Title |
|---|
| FERNANDEZ等.Randomized trial of the immunogenicity of fractional dose regimens of PRP-T Haemophilus influenze type b conjugate vaccine.《THE AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE》.2000,第62卷(第4期),第485－490. * |
| JACOB AMIR等.immunogenicity and safety of a liquid combination of DT-PRP-T vs lyophilized PRP-T reconstituted with DTP.《VACCINE》.1997,第15卷(第2期),第149-154页. * |
| NICOL M.HAEMOPHILUS INFLUENZAE YTPE B CONJUGATE VACCINE DILUTED TENFOLD IN DIPHTHERIA-TETANUS-WHOLE CELL PERTUSSIS VACCINE:A RANDOMIZED TRIAL.《PEDIATRIC INFECTIOUS DISEASE JOUTNAL》.2002,第21卷(第2期),第138－141页. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1968711B (zh) | 2011-01-05 |
| DK1725258T3 (da) | 2010-11-01 |
| EP1725258B1 (en) | 2010-09-08 |
| CA2559996C (en) | 2014-08-05 |
| CA2559996A1 (en) | 2005-09-29 |
| BRPI0508813B1 (pt) | 2019-05-21 |
| ATE480257T1 (de) | 2010-09-15 |
| US20120107346A1 (en) | 2012-05-03 |
| JP4954056B2 (ja) | 2012-06-13 |
| CN102028944A (zh) | 2011-04-27 |
| CN1968711A (zh) | 2007-05-23 |
| JP2007529503A (ja) | 2007-10-25 |
| BRPI0508813B8 (pt) | 2021-05-25 |
| SG151253A1 (en) | 2009-04-30 |
| US20090208526A1 (en) | 2009-08-20 |
| US9259460B2 (en) | 2016-02-16 |
| RU2006136212A (ru) | 2008-04-27 |
| DE602005023422D1 (de) | 2010-10-21 |
| JP2008150397A (ja) | 2008-07-03 |
| WO2005089794A2 (en) | 2005-09-29 |
| EP1725258A2 (en) | 2006-11-29 |
| BRPI0508813A (pt) | 2007-08-07 |
| RU2435609C2 (ru) | 2011-12-10 |
| WO2005089794A3 (en) | 2006-03-09 |
| GB0405787D0 (en) | 2004-04-21 |
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